alanine has been researched along with Acidosis in 64 studies
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As part of a study on the regulation of renal ammoniagenesis in the mouse kidney, we investigated the effect of chronic metabolic acidosis on glutamine synthesis by isolated mouse renal proximal tubules." | 7.72 | Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis. ( Baverel, G; Boghossian, M; Conjard, A; Delage, H; Ferrier, B; Komaty, O; Martin, M, 2003) |
| "In hepatocytes isolated from uremic and control rats, we investigated: (1) the influence of uremia on gluconeogenesis and ureagenesis during incubations with alanine; (2) the kinetics of alanine plasma-membrane transport; (3) the relationships between intracellular alanine concentrations and its metabolism." | 7.72 | Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells. ( Cano, N; El-Mir, MY; Leverve, XM; Meijer, AJ; Novaretti, R; Reynier, JP; Sturm, JM, 2004) |
| "The relationship between hindquarter glutamine release and renal glutamine extraction was studied in rats undergoing chronic metabolic acidosis." | 7.67 | Effect of metabolic acidosis on hindquarter glutamine and alanine release. ( Welbourne, TC, 1986) |
| "Acute metabolic acidosis (AMA) in the dog results in a 48% increase in arterial alanine concentration and an 11% fall in blood glucose." | 7.66 | Preliminary report: the effects of acute acidosis on alanine and glucose metabolism across the liver, gut, kidney, and muscle in the dog. ( Fine, A, 1983) |
| "We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of various causes." | 7.66 | Treatment of lactic acidosis with dichloroacetate. ( Baumgartner, TG; Curry, SH; Harman, EM; Misbin, RI; Stacpoole, PW, 1983) |
| "A shortage of alanine for gluconeogenesis is believed responsible for various forms of hypoglycemia and in particular ketotic hypoglycemia (KH)." | 7.66 | Hypoalaninemia and ketotic hypoglycemia: cause or consequence? ( Sadeghi-Nejad, A; Senior, B; Wolfsdorf, JI, 1982) |
| " This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine." | 7.65 | Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976) |
| "As part of a study on the regulation of renal ammoniagenesis in the mouse kidney, we investigated the effect of chronic metabolic acidosis on glutamine synthesis by isolated mouse renal proximal tubules." | 3.72 | Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis. ( Baverel, G; Boghossian, M; Conjard, A; Delage, H; Ferrier, B; Komaty, O; Martin, M, 2003) |
| "In hepatocytes isolated from uremic and control rats, we investigated: (1) the influence of uremia on gluconeogenesis and ureagenesis during incubations with alanine; (2) the kinetics of alanine plasma-membrane transport; (3) the relationships between intracellular alanine concentrations and its metabolism." | 3.72 | Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells. ( Cano, N; El-Mir, MY; Leverve, XM; Meijer, AJ; Novaretti, R; Reynier, JP; Sturm, JM, 2004) |
| "We investigated the effects of an intravenous load of alpha-ketoglutaric acid, ammonium (NH(4)(+)), and metabolic acidosis on plasma concentration and splanchnic and hindleg tissue exchange of glutamine, glutamate, alanine, and arginine in postabsorptive, anesthetized pigs." | 3.71 | Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig. ( Karlsson, T; Nordgren, A; Wiklund, L, 2002) |
| "Pyruvate transport and carboxylation have been determined in mitochondria from liver and kidney cortex isolated from Wistar rats with acidosis produced by three different treatments: fasting, exercise and ingestion of ammonium chloride." | 3.69 | Mitochondrial pyruvate metabolism in liver and kidney during acidosis. ( Oliver, FJ; Salto, R; Sola, MM; Vargas, AM, 1994) |
| " Because both PGF2 alpha- and TPA-induced inhibition of ammoniagenic response to acute acidosis was prevented by amiloride, the underlying mechanism may involve protein kinase C-mediated changes in intracellular pH." | 3.68 | Signal transduction events whereby PGF2 alpha inhibits the ammoniagenic response to acute acidosis. ( Sahai, A; Sandler, RS; Shayman, JA; Tannen, RL; Xu, G, 1992) |
| " In isolated rat hepatocytes the fall in ureogenesis due to acidosis is associated with decrease in the mitochondrial and cytosolic concentration of citrulline." | 3.67 | The mechanism of inhibition of ureogenesis by acidosis. ( Carter, ND; Cohen, RD; Faus-Dader, M; Heath, R; Henderson, RM; Iles, RA; Metcalfe, H; Monson, JP; Smith, JA, 1984) |
| "The relationship between hindquarter glutamine release and renal glutamine extraction was studied in rats undergoing chronic metabolic acidosis." | 3.67 | Effect of metabolic acidosis on hindquarter glutamine and alanine release. ( Welbourne, TC, 1986) |
| "Acute metabolic acidosis (AMA) in the dog results in a 48% increase in arterial alanine concentration and an 11% fall in blood glucose." | 3.66 | Preliminary report: the effects of acute acidosis on alanine and glucose metabolism across the liver, gut, kidney, and muscle in the dog. ( Fine, A, 1983) |
| "We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of various causes." | 3.66 | Treatment of lactic acidosis with dichloroacetate. ( Baumgartner, TG; Curry, SH; Harman, EM; Misbin, RI; Stacpoole, PW, 1983) |
| "A shortage of alanine for gluconeogenesis is believed responsible for various forms of hypoglycemia and in particular ketotic hypoglycemia (KH)." | 3.66 | Hypoalaninemia and ketotic hypoglycemia: cause or consequence? ( Sadeghi-Nejad, A; Senior, B; Wolfsdorf, JI, 1982) |
| "To determine if activity of the renal glutamate dehydrogenase (GD) pathway changes during chronic acidosis in intact dogs, we assessed the deamination of glutamate formed within renal cells during glutamine and alanine infusions." | 3.66 | Evidence of activation of the renal glutamate dehydrogenase pathway in intact acidotic dogs. ( Lombardo, JV; McCarthy, M; Preuss, HG; Risquez, A, 1981) |
| " Permanent metabolic acidosis due to lactic acidemia as well as hyperpyruvic acidemia and hyperalaninemia were present." | 3.66 | [Pyruvate-dehydrogenase deficiency. Lethal course of the disease during infancy (author's transl)]. ( Becker, K; Berger, R; Bremer, HJ; Przyrembel, H; Walther, B; Wendel, U, 1978) |
| "4 children with ketotic hypoglycemia (KH) showed during a fasting period over 24 hours significant higher decreases of serum alanine levels than normal controls." | 3.66 | [Pathogenesis of ketotic hypoglycemia (author's transl)]. ( Ploier, R; Sommer, R; Tulzer, W, 1979) |
| " They had chronic metabolic acidosis associated with elevated blood levels of lactate, pyruvate, and alanine." | 3.65 | Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes. ( Blass, JP; Hansen, S; Haworth, JC; Perry, TL; Urquhart, N, 1976) |
| " This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine." | 3.65 | Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976) |
| "Acquired Fanconi syndrome has been associated with the long-term ingestion of several nucleoside analogs used to treat chronic hepatitis B virus infection." | 1.51 | A case of entecavir-induced Fanconi syndrome. ( Fujii, T; Kawasoe, K; Nitta, K; Ohta, A, 2019) |
| "Troglitazone was studied in pH-sensitive LLC-PK1-F+ cells to determine the effect on pHi and glutamine metabolism as well as the role of peroxisome proliferator-activated receptor (PPARgamma)-dependent and PPARgamma-independent signaling pathways." | 1.32 | Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism. ( Fowler, R; Friday, E; Nissim, I; Turturro, F; Welbourne, T, 2004) |
| "Diazoxide treatment could be stopped at the age of 1 month." | 1.27 | Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA). ( Aynsley-Green, A; Jenkins, PA; Soltész, G; Weindling, AM, 1983) |
| "3." | 1.27 | The effects of post-exercise glucose and alanine ingestion on plasma carnitine and ketosis in humans. ( Carlin, JI; Olson, EB; Peters, HA; Reddan, WG, 1987) |
| "This study examined ketosis in response to 90 min of running before and after the ingestion of 50 g glucose or 50 g L-alanine in thirty-three athletes." | 1.27 | Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans. ( Koeslag, JH; Levinrad, LI; Lochner, JD; Sive, AA, 1985) |
| "[15N]Glycine was infused into fed, fasted or acidotic humans." | 1.26 | [15N]Glycine metabolism in normal man: the metabolic alpha-amino-nitrogen pool. ( Golden, MH; Jackson, AA, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (82.81) | 18.7374 |
| 1990's | 6 (9.38) | 18.2507 |
| 2000's | 4 (6.25) | 29.6817 |
| 2010's | 1 (1.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, T | 1 |
| Kawasoe, K | 1 |
| Ohta, A | 1 |
| Nitta, K | 1 |
| Conjard, A | 1 |
| Komaty, O | 1 |
| Delage, H | 1 |
| Boghossian, M | 1 |
| Martin, M | 1 |
| Ferrier, B | 1 |
| Baverel, G | 2 |
| PILKINGTON, LA | 1 |
| WELCH, J | 1 |
| PITTS, RF | 2 |
| Welbourne, T | 1 |
| Friday, E | 1 |
| Fowler, R | 1 |
| Turturro, F | 1 |
| Nissim, I | 3 |
| Cano, N | 1 |
| Sturm, JM | 1 |
| Meijer, AJ | 1 |
| El-Mir, MY | 1 |
| Novaretti, R | 1 |
| Reynier, JP | 1 |
| Leverve, XM | 1 |
| Haymond, MW | 1 |
| Pagliara, AS | 1 |
| Monson, JP | 1 |
| Henderson, RM | 1 |
| Smith, JA | 1 |
| Iles, RA | 2 |
| Faus-Dader, M | 1 |
| Carter, ND | 1 |
| Heath, R | 1 |
| Metcalfe, H | 1 |
| Cohen, RD | 2 |
| Fine, A | 1 |
| Aynsley-Green, A | 1 |
| Weindling, AM | 1 |
| Soltész, G | 1 |
| Jenkins, PA | 1 |
| Jeevanandam, M | 1 |
| Long, CL | 1 |
| Birkhahn, RH | 1 |
| Blakemore, WS | 1 |
| Radcliffe, AG | 1 |
| Wolfe, RR | 1 |
| Colpoys, MF | 1 |
| Muhlbacher, F | 1 |
| Wilmore, DW | 1 |
| Stacpoole, PW | 2 |
| Harman, EM | 1 |
| Curry, SH | 1 |
| Baumgartner, TG | 1 |
| Misbin, RI | 1 |
| Wathen, RL | 1 |
| Ward, RA | 1 |
| Harding, GB | 1 |
| Meyer, LC | 1 |
| Wolfsdorf, JI | 1 |
| Sadeghi-Nejad, A | 1 |
| Senior, B | 1 |
| Sestoft, L | 1 |
| Bartels, PD | 1 |
| Folke, M | 1 |
| Lombardo, JV | 1 |
| Risquez, A | 1 |
| McCarthy, M | 1 |
| Preuss, HG | 1 |
| Lemieux, G | 3 |
| Watford, M | 1 |
| Vinay, P | 3 |
| Gougoux, A | 3 |
| Papanastasiou, D | 1 |
| Lehnert, W | 1 |
| Schuchmann, L | 1 |
| Hommes, FA | 1 |
| Jackson, AA | 1 |
| Golden, MH | 1 |
| Crie, JS | 1 |
| Wildenthal, K | 1 |
| Oliver, FJ | 1 |
| Salto, R | 1 |
| Sola, MM | 1 |
| Vargas, AM | 1 |
| Gstraunthaler, GJ | 1 |
| Bhujwalla, ZM | 1 |
| Shungu, DC | 1 |
| Chatham, JC | 1 |
| Wehrle, JP | 1 |
| Glickson, JD | 1 |
| Cattano, C | 1 |
| Lin, Z | 1 |
| Nordgren, A | 1 |
| Karlsson, T | 1 |
| Wiklund, L | 1 |
| Israels, S | 1 |
| Haworth, JC | 2 |
| Dunn, HG | 1 |
| Applegarth, DA | 1 |
| Perry, TL | 1 |
| Blass, JP | 1 |
| Hansen, S | 1 |
| Urquhart, N | 1 |
| Tada, K | 2 |
| Takada, G | 1 |
| Omura, K | 1 |
| Itokawa, Y | 1 |
| Lloyd, MH | 1 |
| Walton, B | 1 |
| Hamilton, CA | 1 |
| Wendel, U | 1 |
| Przyrembel, H | 1 |
| Becker, K | 1 |
| Walther, B | 1 |
| Berger, R | 1 |
| Bremer, HJ | 1 |
| Ploier, R | 1 |
| Tulzer, W | 1 |
| Sommer, R | 1 |
| Brière, R | 1 |
| Moore, GW | 1 |
| Kornhauser, DM | 1 |
| Weik, H | 1 |
| Zander, HD | 1 |
| Maesaka, H | 1 |
| Komiya, K | 1 |
| Misugi, K | 1 |
| Saudubray, JM | 1 |
| Marsac, C | 1 |
| Cathelineau, CL | 1 |
| Besson Leaud, M | 1 |
| Leroux, JP | 1 |
| Wilensky, JT | 1 |
| Goldberg, MF | 1 |
| Ziyai, F | 1 |
| Wong, PW | 1 |
| Sahai, A | 2 |
| Sandler, RS | 1 |
| Xu, G | 1 |
| Shayman, JA | 1 |
| Tannen, RL | 2 |
| Laughrey, E | 1 |
| Welbourne, TC | 1 |
| Klim, RA | 1 |
| Albajar, M | 1 |
| Hems, R | 1 |
| Williamson, DH | 1 |
| Carlin, JI | 1 |
| Olson, EB | 1 |
| Peters, HA | 1 |
| Reddan, WG | 1 |
| Halperin, M | 1 |
| Cersosimo, E | 1 |
| Williams, PE | 1 |
| O'Donovan, D | 1 |
| Lacy, DB | 1 |
| Abumrad, NN | 1 |
| Koeslag, JH | 1 |
| Levinrad, LI | 1 |
| Lochner, JD | 1 |
| Sive, AA | 1 |
| Greene, HL | 1 |
| Stifel, FB | 1 |
| Herman, RH | 1 |
| Brunette, MG | 1 |
| Delvin, E | 1 |
| Hazel, B | 1 |
| Scriver, CR | 1 |
| Heitzman, RJ | 1 |
| Walker, MS | 1 |
| Chaussain, JL | 1 |
| Georges, P | 1 |
| Olive, G | 1 |
| Job, JC | 1 |
| Frimpter, GW | 1 |
| Terlow, MJ | 1 |
| Lake, BD | 1 |
| Lloyd, JK | 1 |
| Hackett, TN | 1 |
| Bray, PF | 1 |
| Ziter, FA | 1 |
| Nyhan, WL | 1 |
| Creer, KM | 1 |
| Corbeel, L | 1 |
| Beckels, R | 1 |
| Müller, J | 1 |
| Schäfer, M | 1 |
| Bergman, EN | 1 |
| Kaufman, CF | 1 |
| Wolff, JE | 1 |
| Williams, HH | 1 |
| Donnelly, PE | 1 |
| Turtle, JR | 1 |
| Marliss, EB | 1 |
| Aoki, TT | 1 |
| Toews, CJ | 1 |
| Felig, P | 1 |
| Connon, JJ | 1 |
| Kyner, J | 1 |
| Huckabee, WE | 1 |
| Cahill, GF | 1 |
| Brown, RE | 1 |
| Madge, GE | 1 |
| Mamunes, P | 1 |
| Kekomäki, M | 1 |
| Louhimo, I | 1 |
| Tanaka, K | 1 |
| Miller, EM | 1 |
| Isselbacher, KJ | 1 |
| Christophe, J | 1 |
| Winand, J | 1 |
| Kutzner, R | 1 |
| Hebbelinck, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for alanine and Acidosis
| Article | Year |
|---|---|
Ketotic hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adrenocorticotropic Hormone; Adult; Alan | 1983 |
Lactic acidosis in childhood.
Topics: Acidosis; Alanine; Autopsy; Brain; Brain Diseases; Central Nervous System Diseases; Child; Child, Pr | 1976 |
Regulation of glutamine metabolism in dog kidney in vivo.
Topics: Acid-Base Equilibrium; Acidosis; Adenosine Triphosphate; Alanine; Ammonia; Animals; Aspartic Acid; B | 1986 |
Thiamine-responsive lactic acidosis.
Topics: Acidosis; Alanine; Biotin; Carbohydrate Metabolism, Inborn Errors; Dietary Carbohydrates; Female; Hu | 1974 |
Aminoacidurias due to inherited disorders of metabolism. 2.
Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Arginase; Arginine; Carbamates; Citrulline; | 1973 |
Starvation in pregnancy: metabolic changes.
Topics: Abortion, Therapeutic; Acidosis; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Blood; Blood G | 1973 |
58 other studies available for alanine and Acidosis
| Article | Year |
|---|---|
A case of entecavir-induced Fanconi syndrome.
Topics: Acidosis; Acute Kidney Injury; Adenine; Aged; Alanine; Antiviral Agents; Fanconi Syndrome; Guanine; | 2019 |
Inhibition of glutamine synthetase in the mouse kidney: a novel mechanism of adaptation to metabolic acidosis.
Topics: Acidosis; Actins; Alanine; Ammonia; Animals; Carbon; Female; Gluconeogenesis; Glutamate Dehydrogenas | 2003 |
RELATIONSHIP OF PNH3 OF TUBULAR CELLS TO RENAL PRODUCTION OF AMMONIA.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Body Fluids; Dog | 1965 |
Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.
Topics: Acid-Base Equilibrium; Acidosis; Alanine; Alkaloids; Animals; Antineoplastic Agents; Benzhydryl Comp | 2004 |
Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells.
Topics: Acidosis; Alanine; Animals; Cells, Cultured; Gluconeogenesis; Hepatocytes; Kidney Failure, Chronic; | 2004 |
The mechanism of inhibition of ureogenesis by acidosis.
Topics: Acidosis; Alanine; Animals; Citrulline; Cytosol; Gluconeogenesis; Hydrogen-Ion Concentration; Lactat | 1984 |
Preliminary report: the effects of acute acidosis on alanine and glucose metabolism across the liver, gut, kidney, and muscle in the dog.
Topics: Acidosis; Acute Disease; Alanine; Animals; Blood Glucose; Digestive System; Dogs; Glucose; Kidney; L | 1983 |
Transient lactic acidosis and hyperalaninaemia associated with neonatal hyperinsulinaemic hypoglycaemia: the effects of dichloroacetate (DCA).
Topics: Acetates; Acidosis; Alanine; Diazoxide; Dichloroacetic Acid; Humans; Hypoglycemia; Infant; Infant, N | 1983 |
Evaluation of whole body nitrogen kinetics in acute metabolic acidosis.
Topics: Acidosis; Alanine; Ammonia; Animals; Blood Urea Nitrogen; Dogs; Kinetics; Male; Mathematics; Models, | 1983 |
Ketone-glucose interaction in fed, fasted, and fasted-infected sheep.
Topics: Acidosis; Alanine; Animals; Blood Glucose; Body Temperature; Communicable Diseases; Fasting; Fatty A | 1983 |
Treatment of lactic acidosis with dichloroacetate.
Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Adolescent; Adult; Aged; Alanine; Bicarbonates; Blood Pre | 1983 |
Acid-base and metabolic responses to anion infusion in the anesthetized dog.
Topics: Acetates; Acid-Base Equilibrium; Acidosis; Alanine; Anesthesia; Animals; Anions; Bicarbonates; Blood | 1982 |
Hypoalaninemia and ketotic hypoglycemia: cause or consequence?
Topics: Acidosis; Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Fasting; Female; Human | 1982 |
Pathophysiology of metabolic acidosis: effect of low pH on the hepatic uptake of lactate, pyruvate and alanine.
Topics: Acidosis; Alanine; Animals; Blood Glucose; Female; Hydrogen-Ion Concentration; Lactates; Lactic Acid | 1982 |
Evidence of activation of the renal glutamate dehydrogenase pathway in intact acidotic dogs.
Topics: Acidosis; Alanine; Alkalosis; Ammonia; Animals; Deamination; Dogs; Enzyme Activation; Female; Glutam | 1981 |
Metabolic changes in skeletal muscle during chronic metabolic acidosis.
Topics: Acidosis; Alanine; Amino Acids; Animals; Chronic Disease; Diaphragm; Glutamates; Glutamine; Kinetics | 1980 |
[Chronic infantile lactate acidosis].
Topics: Acidosis; Alanine; Amino Acids; Anorexia; Hepatomegaly; Humans; Infant; Lactates; Male; Muscle Tonus | 1980 |
[15N]Glycine metabolism in normal man: the metabolic alpha-amino-nitrogen pool.
Topics: Acidosis; Adult; Alanine; Ammonia; Deamination; Fasting; Glutamates; Glycine; Humans; Male; Nitrogen | 1980 |
Influence of acidosis and lactate on protein degradation in adult and fetal hearts.
Topics: Acidosis; Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Female; Heart; Lactates; Male; | 1980 |
Mitochondrial pyruvate metabolism in liver and kidney during acidosis.
Topics: Acidosis; Alanine; Ammonium Chloride; Animals; Fasting; Gluconeogenesis; Kidney Cortex; L-Lactate De | 1994 |
Ammoniagenesis in renal cell culture. A comparative study on ammonia metabolism of renal epithelial cell lines.
Topics: Acidosis; Alanine; Ammonia; Animals; Cells, Cultured; Dogs; Epithelium; Hydrogen-Ion Concentration; | 1994 |
Glucose metabolism in RIF-1 tumors after reduction in blood flow: an in vivo 13C and 31P NMR study.
Topics: Acidosis; Alanine; Animals; Autoradiography; Blood Glucose; Carbon Isotopes; Energy Metabolism; Fema | 1994 |
Acid-base regulation of hepatic glutamine metabolism and ureagenesis: study with 15N.
Topics: Acid-Base Equilibrium; Acidosis; Alanine; Alkalosis; Ammonia; Animals; Aspartic Acid; Glutamine; In | 1993 |
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig.
Topics: Acidosis; Alanine; Amino Acids; Animals; Blood Gas Analysis; Disease Models, Animal; Dose-Response R | 2002 |
Lactic acidosis in three sibs due to defects in both pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase complexes.
Topics: Acidosis; Alanine; Carbohydrate Metabolism, Inborn Errors; Electron Transport Complex IV; Female; Gl | 1976 |
Congenital lactic acidosis due to pyruvate carboxylase deficiency: absence of an inhibitor of TPP-ATP phosphoryl transferase.
Topics: Acidosis; Alanine; Brain Stem; Child, Preschool; Encephalomalacia; Female; Humans; Infant; Intellect | 1978 |
Effect of phenformin on gluconeogenesis from lactate and intracellular pH in the isolated perfused guinea pig liver.
Topics: Acidosis; Alanine; Animals; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose; Guinea Pigs; Hydro | 1975 |
[Pyruvate-dehydrogenase deficiency. Lethal course of the disease during infancy (author's transl)].
Topics: Acidosis; Alanine; Carbohydrate Metabolism, Inborn Errors; Female; Humans; Infant; Infant, Newborn; | 1978 |
[Pathogenesis of ketotic hypoglycemia (author's transl)].
Topics: Acidosis; Alanine; Child; Child, Preschool; Deoxyglucose; Diazoxide; Epinephrine; Fasting; Female; H | 1979 |
Relationship between lactate and glutamine metabolism in vitro by the kidney: differences between dog and rat and importance of alanine synthesis in the dog.
Topics: Acidosis; Alanine; Aminooxyacetic Acid; Animals; Dichloroacetic Acid; Dogs; Fluoroacetates; Gluconeo | 1979 |
Metabolic effects of dichloroacetate in patients with diabetes mellitus and hyperlipoproteinemia.
Topics: Acetates; Acidosis; Adult; Aged; Alanine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus; Di | 1978 |
[Effect of alanine on acetonemia in cows and on phlorhizin-induced acetonemia in sheep].
Topics: Acidosis; Alanine; Animals; Cattle; Cattle Diseases; Female; Phlorhizin; Sheep | 1975 |
Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid.
Topics: Acidosis; Alanine; Female; Glucose; Humans; Infant; Intellectual Disability; Lactates; Liver; Metabo | 1976 |
Neonatal congenital lactic acidosis with pyruvate carboxylase deficiency in two siblings.
Topics: Acetoacetates; Acidosis; Alanine; Female; Humans; Hydroxybutyrates; Infant, Newborn; Infant, Newborn | 1976 |
Infantile cataracts, Coats' disease, and ketotic hypoglycemia.
Topics: Acidosis; Alanine; Blood Glucose; Cataract; Cataract Extraction; Fasting; Female; Glaucoma; Humans; | 1976 |
Signal transduction events whereby PGF2 alpha inhibits the ammoniagenic response to acute acidosis.
Topics: Acidosis; Acute Disease; Alanine; Amiloride; Ammonia; Animals; Calcium Channel Blockers; Cell Line; | 1992 |
Relationship between intracellular pH and ammonia metabolism in LLC-PK1 cells.
Topics: Acidosis; Acidosis, Respiratory; Alanine; Alkalosis; Alkalosis, Respiratory; Ammonia; Cell Line; Cyt | 1990 |
Effect of metabolic acidosis on hindquarter glutamine and alanine release.
Topics: Acidosis; Alanine; Ammonia; Animals; Chronic Disease; Glutamates; Glutamic Acid; Glutamine; Hindlimb | 1986 |
Effects of chronic uraemia on the formation of glucose and urea plus ammonia from L-alanine, L-glutamine and L-serine in isolated rat hepatocytes.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Gluconeogenesis; Glutaminase; Glutamine; In Vitro | 1986 |
The effects of post-exercise glucose and alanine ingestion on plasma carnitine and ketosis in humans.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Alanine; Carnitine; Fasting; Fatty Acids, Nonesterified; Glu | 1987 |
Role of acidosis in regulating hepatic nitrogen metabolism during fasting in conscious dog.
Topics: Acidosis; Alanine; Ammonia; Animals; Bicarbonates; Blood Glucose; Catecholamines; Dogs; Fasting; Fem | 1987 |
Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans.
Topics: 3-Hydroxybutyric Acid; Acidosis; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Gluco | 1985 |
"Ketotic hypoglycemia" due to hepatic fructose-1,6-diphosphatase deficiency: treatment with folic acid.
Topics: Acidosis; Alanine; Aldehyde-Lyases; Child, Preschool; Fasting; Female; Folic Acid; Fructose; Fructos | 1972 |
Thiamine-responsive lactice acidosis in a patient with deficient low-KM pyruvate carboxylase activity in liver.
Topics: Acidosis; Adrenocorticotropic Hormone; Alanine; Amino Acids; Diet Therapy; Female; Gluconeogenesis; | 1972 |
The antiketogenic action of an anabolic steroid administered to ketotic cows.
Topics: Acetoacetates; Acidosis; Alanine; Amino Acids; Anabolic Agents; Androstenes; Animal Feed; Animals; A | 1973 |
Glycemic response to 24-hour fast in normal children and children with ketotic hypoglycemia: II. Hormonal and metabolic changes.
Topics: Acidosis; Alanine; Amino Acids; Autoanalysis; Blood Glucose; Child; Child, Preschool; Fasting; Fatty | 1974 |
Chronic lactic acidosis in association with myopathy.
Topics: Acidosis; Alanine; Child; Chronic Disease; Female; Genes, Dominant; Humans; Lactates; Metabolic Dise | 1973 |
A metabolic myopathy associated with chronic lactic acidemia, growth failure, and nerve deafness.
Topics: Acidosis; Alanine; Child; Chromatography, Paper; Deafness; Electromyography; Female; Growth Disorder | 1973 |
Recurrent attacks of ketoacidosis with hyperlacticacidaemia, hyperpyruvicacidaemia and hyperalaninaemia.
Topics: Acidosis; Alanine; Biopsy; Child; Female; Glucose Tolerance Test; Humans; Ketoglutaric Acids; Lactat | 1973 |
[Free amino acids in the blood plasma of cows with subclinical ketosis].
Topics: Acidosis; Adrenal Glands; Alanine; Amino Acids; Animals; Cattle; Cattle Diseases; Chromatography, Pa | 1973 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli | 1974 |
Ketotic hypoglycaemia due to hypoalaninaemia.
Topics: Acidosis; Alanine; Child; Gluconeogenesis; Humans; Hypoglycemia; Male; Metabolic Diseases; Syndrome | 1974 |
Amino acid metabolism in lactic acidosis.
Topics: Acidosis; Adult; Aged; Alanine; Amino Acids; Carbon Dioxide; Carbon Isotopes; Chromatography, Ion Ex | 1972 |
Chronic lactic acidosis in infancy.
Topics: Acidosis; Alanine; Autopsy; Child, Preschool; Female; Humans; Infant; Lactates; Lipid Metabolism; Me | 1972 |
Observations on plasma amino acid concentrations during haemorrhagic shock in the rabbit.
Topics: Acidosis; Acidosis, Respiratory; Alanine; Amino Acids; Animals; Blood; Blood Urea Nitrogen; Chromato | 1971 |
Hypoglycin A: a specific inhibitor of isovaleryl CoA dehydrogenase.
Topics: Acidosis; Alanine; Amino Acid Metabolism, Inborn Errors; Animals; Butyrates; Caproates; Carbon Dioxi | 1971 |
Metabolism of amino acids by the perfused rat kidney.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Glucose; Glutamates; Glutamine; Gly | 1971 |
Amino acid levels in plasma, liver, muscle, and kidney during and after exercise in fasted and fed rats.
Topics: Acidosis; Alanine; Amino Acids; Animals; Aspartic Acid; Fasting; Gluconeogenesis; Glutamates; Glutam | 1971 |