adenosine has been researched along with Aging in 181 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (22.10) | 18.7374 |
| 1990's | 61 (33.70) | 18.2507 |
| 2000's | 47 (25.97) | 29.6817 |
| 2010's | 19 (10.50) | 24.3611 |
| 2020's | 14 (7.73) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, DY; Peng, F; Shen, Q; Xue, YP; Xue, YZ; Zhang, SJ; Zheng, YG | 1 |
| Bhatti, SA; Imran, I; Nasir, A; Rehman, MHU; Samad, N | 1 |
| Gokulnath, P; Guo, S; Hou, Z; Lehmann, HI; Lei, J; Li, G; Shang, H; Xing, Y; Yang, S; Yang, X; You, L; Zhang, G | 1 |
| Arcidiacono, OA; Bártová, E; Čegan, R; Fila, P; Krejčí, J; Pacherník, J; Pešl, M; Pirk, J; Radaszkiewicz, K | 1 |
| Conde, SV; Gonzalez, C; Martins, FO; Melo, BF; Monteiro, EC; Olea, E; Prieto-Lloret, J; Ribeiro, MJ; Sacramento, JF | 1 |
| Chao, YM; Hsu, WH; Huang, YJ; Lin, YL; Shiao, YJ | 1 |
| Morris, A | 1 |
| Albasanz, JL; Griñán-Ferré, C; Martín, M; Pallàs, M; Sánchez-Melgar, A | 1 |
| De Luca, G; Gioscia, R; Khedi, E; Marcolongo, M; Nardin, M; Negro, F; Suryapranata, H; Tonon, F; Verdoia, M | 1 |
| Albasanz, JL; Martín, M; Pallàs, M; Sánchez-Melgar, A | 1 |
| Arcidiacono, OA; Bártová, E; Krejčí, J | 1 |
| Allen, EG; Dai, Q; Duan, R; Guo, Z; He, C; Jin, P; Kang, Y; Li, Y; Pajdzik, K; Shafik, AM; Wu, H; Yao, B; Zhang, F | 1 |
| De Luca, G; Gioscia, R; Kedhi, E; Suryapranata, H; Verdoia, M | 1 |
| Fukumoto, T; Hao, X; Kossenkov, AV; Li, F; Lin, J; Liu, P; Nacarelli, T; Simon, MC; Zhang, R | 1 |
| Chu, K; Dai, ZH; Gu, JY; He, Y; Ji, YX; Jiang, ZX; Li, W; Li, ZY; Sun, NX; Wang, YN; Yang, F | 1 |
| Albasanz, JL; Martín, M; Pallàs, M; Palomera-Ávalos, V; Sánchez-Melgar, A | 1 |
| Kerr, MI; Richardson, MJ; Wall, MJ | 1 |
| Ito, MA; Kimura, J; Matsuoka, I; Murakawa, M; Takahashi-Sato, K | 1 |
| Belderbos, M; Bergelson, I; Bingham, T; Bont, L; Burl, S; Gelinas, L; Kampmann, B; Kollmann, T; Levy, O; Millán, JL; Pettengill, M; Robson, S; Tresenriter, M; Usheva, A | 1 |
| Dhillon, S | 1 |
| Asztély, AK; Berggren, A; Castellheim, A; Jeppsson, A; Nelander, K; Nylander, S; Romlin, BS; Söderlund, F | 1 |
| Basheer, R; Gvilia, I; Kalinchuk, A; Kostin, A; McGinty, D; Suntsova, N; Szymusiak, R | 1 |
| Hu, K; Kang, C; Osei, W; Qin, J | 1 |
| Oja, SS; Saransaari, P | 1 |
| Ribeiro, JA; Sebastião, AM | 1 |
| López, D; Mármol, F; Martínez, N; Mitjavila, MT; Peralta, C; Puig-Parellada, P; Roselló-Catafau, J; Sánchez, J; Xaus, C | 1 |
| Baghdoyan, HA; Lydic, R; Watson, CJ; Watson, SL | 1 |
| Marshall, JM; Omar, NM | 1 |
| de Magalhaes, JP; Khrapko, K; Kraytsberg, Y; Levanon, EY; Nicholas, A; Richfield, EK | 1 |
| Batuca, JR; González, C; Monteiro, EC; Monteiro, TC; Obeso, A | 1 |
| Crecelius, AR; Dinenno, FA; Kirby, BS; Voyles, WF | 1 |
| Costenla, AR; Diógenes, MJ; Fontinha, BM; Jerónimo-Santos, A; Lopes, LV; Ribeiro, JA; Sebastião, AM; Sousa, VC | 1 |
| Agostinho, PM; Canas, PM; Costenla, AR; Cunha, RA; de Mendonça, A; Diógenes, MJ; Maroco, J; Nogueira, C; Ribeiro, JA; Rodrigues, RJ | 1 |
| Correia, AM; Pousinha, PA; Ribeiro, JA; Sebastião, AM | 1 |
| Dobson, JG; Fenton, RA | 2 |
| Chiu, SY; Verbny, Y; Zhang, CL | 1 |
| Delp, MD; Muller-Delp, JM; Ramsey, MW; Spier, SA | 1 |
| Bringmann, A; Grosche, J; Reichenbach, A; Uckermann, O | 1 |
| Baumann, R; Dragon, S; Gotz, R | 1 |
| Headrick, JP; Hinschen, AK; Rose'Meyer, RB | 3 |
| Ashton, KJ; Headrick, JP; Holmgren, K; Matherne, GP; Peart, J; Willems, L | 1 |
| Cunha, RA; de Mendonca, A; Oliveira, CR; Rebola, N; Ribeiro, JA; Sebastião, AM | 1 |
| HARARY, I; SATO, E | 1 |
| Apstein, CS; Koh, SG; Saupe, KW; Sobol, SC | 1 |
| Garnham, B; Headrick, JP; Willems, L | 1 |
| Baker, DJ; Scaramuzzi, RJ | 1 |
| Blanco-Centurion, C; Gerashchenko, D; Murillo-Rodriguez, E; Salin-Pascual, RJ; Shiromani, PJ | 1 |
| Armour, JA; Chen, RP; Thompson, GW | 1 |
| Farkas, E; Keijser, JN; Luiten, PG; Meerlo, P; Nyakas, C; Roman, V | 1 |
| Quan, F; Quan, W; Ramirez, M; Taylor, C; Vinogradov, M; Walker, P | 1 |
| Ashton, KJ; Headrick, JP; Willems, L | 1 |
| Dinenno, FA; Joyner, MJ; Masuki, S | 1 |
| Przyklenk, K; Whittaker, P | 1 |
| Haxhiu, MA; Martin, RJ; Mayer, CA; Wilson, CG | 1 |
| Hashimoto, M; Hossain, S; Shido, O; Tanabe, Y | 1 |
| Jenner, TL; Rose'meyer, RB | 2 |
| Cater, J; Galante, RJ; Mackiewicz, M; Nikonova, EV; Pack, AI; Romer, MA; Zimmermann, JE | 1 |
| Hong, IK; Im, KC; Kang, DH; Moon, DH; Pai, M; Song, JK; Yang, YJ; Yun, SC | 1 |
| Huxley, VH; Wang, J | 1 |
| Blank, T; Nijholt, I; Spiess, J | 1 |
| Headrick, JP; Peart, JN | 1 |
| Assaife-Lopes, N; Diógenes, MJ; Pinto-Duarte, A; Ribeiro, JA; Sebastião, AM | 1 |
| Canas, PM; Cunha, RA; Lopes, LV; Oliveira, CR; Rodrigues, RJ | 1 |
| Amabile, N; Chen, Q; Heiss, C; Momma, TY; Natarajan, S; Sievers, RE; Springer, ML; Yeghiazarians, Y | 1 |
| Chang, H; Farahbakhsh, Z; Hoffman, BB; Reaven, G | 1 |
| Stone, TW | 1 |
| Bynum, JW | 1 |
| Frolkis, RA; Frolkis, VV; Gunina, LM; Pugach, BV; Rushkevich, YE | 1 |
| Baglajewski, T; Radulovacki, M; Virus, RM | 1 |
| Good, RA; Ikehara, S; Modak, MJ; Pahwa, RN | 1 |
| Frolkis, RA; Frolkis, VV; Golovchenko, SF; Medved, VI | 1 |
| Chabannes, B; Cronenberger, L; Gharib, A; Pacheco, H; Sarda, N | 1 |
| Janson, VE; Owens, LK; Sastry, BV | 1 |
| Braun, LD; Cornford, EM; Oldendorf, WH | 1 |
| Bol, A; Camici, PG; de Bruyne, B; Impallomeni, M; Melin, JA; Olivotto, I; Radvan, J; Rosen, SD; Uren, NG; Wijns, W | 1 |
| Constantino, MC; Cunha, RA; Ribeiro, JA; Sebastião, AM | 1 |
| Corsi, C; Fratti, S; Pazzagli, M; Pedata, F; Pepeu, G | 1 |
| Bravo, M; Gallo, C; Lopez-Saez, JF; Navarrete, MH; Pincheira, J | 1 |
| Chiu, SY; Kriegler, S | 1 |
| Andros, E; Gerber, JG; Nies, AS; Suteparuk, S | 1 |
| Burmester, JG; Clemens, PC; Prankel, BH | 1 |
| Etzel, BA; Guillet, R | 1 |
| Gregerman, RI | 1 |
| Daval, JL; Koziel, V; Nicolas, F; Oillet, J | 1 |
| Hultgãrdh-Nilsson, A; Jonzon, B; Krondahl, U; Nilsson, J; Querol-Ferrer, V | 1 |
| Schiffmann, SN; Vanderhaeghen, JJ | 1 |
| Araki, T; Kanai, Y; Kato, H; Kogure, K | 1 |
| Hou, HX; Hyman, PE; Snape, WJ; Tomomasa, T; Willenbucher, R | 1 |
| Halfhide, EJ; Hourani, SM; Kitchen, I; Lee, BS; Nicholls, J | 1 |
| Dobson, JG; Romano, FD | 1 |
| Montamat, SC; Mudumbi, RV; Olson, RD; Vestal, RE | 1 |
| Akita, T; Joyner, RW; Kumar, R | 1 |
| Dobson, JG; Fenton, RA; Sawmiller, DR | 2 |
| Headrick, JP | 1 |
| Bjur, RA; Hashimoto, M; Hattori, K; Masumura, S; Shinozuka, K; Westfall, DP | 1 |
| Lesnefsky, EJ; Lust, WD; Ramani, K; Whittingham, TS | 1 |
| Berr, SS; Headrick, JP; Matherne, GP | 1 |
| Elnazir, B; Kumar, P; Marshall, JM | 1 |
| Noma, A; Takano, M | 1 |
| Fredholm, BB; Georgiev, V; Johansson, B | 1 |
| Gür, S | 1 |
| Sánchez-Prieto, J; Vázquez, E | 1 |
| Friedman, E; Horwitz, J; Pelleg, A; Roberts, J; Snyder, DL; Wang, W | 1 |
| Andros, EA; Gerber, JG | 1 |
| Jackson, EK; Kusaka, H; Li, P; Tofovic, SP | 1 |
| Betto, P; Ferré, S; Fuxe, K; Pézzola, A; Popoli, P; Reggio, R; Ricciarello, G; Rimondini, R | 1 |
| Avoli, M; Descombes, S; Psarropoulou, C | 1 |
| Gamoh, S; Hashimoto, M; Kunitomo, M; Kwon, YM; Masumura, S; Shahdat, HM; Shinozuka, K; Tanabe, Y; Tanaka, Y | 1 |
| Levitsky, S; McCully, JD; Parker, RA; Uematsu, M | 1 |
| Hourani, SM; Kitchen, I; Peachey, JA | 1 |
| Gamoh, S; Hara, T; Hashimoto, M; Hossain, MS; Kunitomo, M; Kwon, YM; Masumura, S; Shinozuka, K; Tanabe, Y | 1 |
| Dobson, JG; Duffy, AJ; Fenton, RA; Graybill, CA; Lorbar, M | 1 |
| Bianchi, L; Corsi, C; Melani, A; Pedata, F; Pepeu, G | 2 |
| Crisanti, KC; Fewell, JE | 1 |
| Cunha, RA; Lopes, LV; Ribeiro, JA | 2 |
| Friedman, E; Gao, E; Gao, F; Horwitz, J; Ma, XL; Pelleg, A; Snyder, DL; Xu, J | 1 |
| Angelatou, F; Ekonomou, A; Pagonopoulou, O | 1 |
| Cunha, RA; Pereira, MF; Ribeiro, JA | 1 |
| Jacks, SM; Kapicka, CL; Montamat, SC; Mudumbi, RV; Olson, RD; Vestal, RE | 1 |
| Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL | 1 |
| Bianchi, L; Corsi, C; Melani, A; Pedata, F | 1 |
| Cunha, RA | 1 |
| Cunha, RA; de Mendonça, A; Ribeiro, JA; Sebastião, AM | 1 |
| Almeida, T; Cunha, RA; Ribeiro, JA | 1 |
| Camici, PG; Chareonthaitawee, P; Kaufmann, PA; Rimoldi, O | 1 |
| Blackburn, MR; Chunn, JL; Fozard, JR; Volmer, JB; Zhong, H | 1 |
| Banjac, A; Horvat, A; Kanazir, D; Nedeljković, N; Nikezić, G | 1 |
| Latchman, DS; Schulman, D; Yellon, DM | 1 |
| Minabe, Y; Muneoka, KT; Shirayama, Y; Takigawa, M | 1 |
| Alzheimer, C; Sickmann, T | 1 |
| Corbin, JD; Sugden, PH | 1 |
| Berkowitz, BA; Blume, AS; Cohen, ML | 1 |
| Arendes, J; Müller, WE; Schröder, CH; Zahn, RK | 1 |
| Kim, HD | 1 |
| Hultgardh-Nilsson, A; Jonzon, B; Nilsson, J; Querol-Ferrer, V; Ringertz, NR | 1 |
| Jin, ZL; Lee, TF; Wang, LC | 1 |
| Chen, PC; Giannotta, SL; Jiang, HX; Sobin, SS | 1 |
| Bauman, LA; Gribkoff, VK | 1 |
| Gobran, LI; Griese, M; Rooney, SA | 1 |
| Cook, JJ; Mayrovitz, HN; Tuma, RF; Vasthare, US; Wailgum, TD | 1 |
| Brady, FO | 1 |
| Bowersox, S; Dement, W; Hawkins, M; Mignot, E; O'Connor, S; Radulovacki, M | 1 |
| Aranda, JV; Beharry, K; Farri, E; Laudignon, N | 1 |
| Dobson, JG; Fenton, RA; Romano, FD | 1 |
| Matsugi, T; Moritoki, H; Takase, H; Tanioka, A; Ueda, H | 1 |
| Furth, ED; Goldberg, AP; Rogus, EM; Rolband, GC; Staddon, JM | 1 |
| Berne, RM; Coleman, SD; Headrick, JP; Matherne, GP | 1 |
| Berne, RM; Headrick, JP; Matherne, GP | 1 |
| Barrera, CM; Dohanich, GP; Dunlap, WP; Hunter, RE | 1 |
| Böhm, M; Diet, F; Erdmann, E; Kemkes, B; Wankerl, M | 1 |
| Dobson, JG; Ethier, MF; Hickler, RB | 1 |
| Gharib, A; Reynaud, D; Sarda, N | 1 |
| Aranda, JV; Beharry, K; Laudignon, N; Sasyniuk, BI | 1 |
| Burnstock, G; Reilly, WM; Saville, VL | 1 |
| O'Brien, DR; Rall, TW | 1 |
| Lehne, RA; Rall, TW | 1 |
| Alyono, D; Bache, RJ; Dai, XZ; Sublett, E | 1 |
| Binder, B; Rall, TW; Shonk, RF | 1 |
| Marangos, PJ; Morgan, PF | 1 |
| Sparks, HV; Toma, BS; Wangler, RD | 1 |
| Giovannelli, L; Giovannini, MG; Pedata, F; Pepeu, G | 1 |
| Buckley, NM; Diamant, S; Frasier, ID; Owusu, K | 1 |
| Bush, P; Chagoya de Sánchez, V; Souness, JE | 1 |
| Bian, K; Inoue, S; Toda, N | 1 |
| Geiger, JD | 1 |
| Barbieri, MC; Ciboddo, GF; Crosti, F; Inversi, F; Navone, P; Pavoni, D; Quarenghi, S; Rugarli, C; Vezzoni, P | 1 |
| Miyazaki, M; Shimizu, I; Toda, N | 1 |
| Shimizu, I; Toda, N | 1 |
| Lee, TJ; Nickols, GA; Shirasaki, Y | 1 |
| DeWitt, DF; Sparks, HV; Toma, BS; Wangler, RD | 1 |
| Carnegie, PR; Jones, GM | 1 |
| Moore, MM; Perkins, JP | 1 |
| Rennert, OM; Sander, EG; Short, NA | 1 |
| Slaughter, JC | 1 |
12 review(s) available for adenosine and Aging
| Article | Year |
|---|---|
Biological synthesis of nicotinamide mononucleotide.
Topics: Adenosine; Adenosine Triphosphate; Aging; Cytokines; Humans; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nucleotides; Ribose; Xylose | 2021 |
RNA modifications in aging-associated cardiovascular diseases.
Topics: Adenosine; Aging; Cardiovascular Diseases; Humans; Ribose; RNA; RNA, Long Noncoding; RNA, Messenger | 2022 |
Ticagrelor: a review of its use in adults with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Administration, Oral; Aging; Combined Modality Therapy; Coronary Artery Bypass; Evidence-Based Medicine; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Risk; Thrombosis; Ticagrelor | 2015 |
Adenosine receptors and the central nervous system.
Topics: Adenosine; Aging; Animals; Brain; Brain-Derived Neurotrophic Factor; Humans; Neurotransmitter Agents; Pain; Receptors, Cannabinoid; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Sleep; Synaptic Transmission | 2009 |
Possible therapeutic benefits of adenosine-potentiating drugs in reducing age-related degenerative disease in dogs and cats.
Topics: Adenosine; Aging; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Neurodegenerative Diseases; Neuroprotective Agents | 2003 |
Adenosine-mediated cardioprotection in the aging myocardium.
Topics: Adenosine; Aged; Aging; Animals; Antioxidants; Humans; Myocardium; Phospholipases; Protein Kinase C; Receptors, Purinergic P1; Signal Transduction | 2005 |
Treatment strategies of age-related memory dysfunction by modulation of neuronal plasticity.
Topics: Acetylcholine; Adenosine; Aging; Animals; Calcium Channels, L-Type; Humans; Memory Disorders; Nerve Growth Factors; Neuronal Plasticity; Potassium Channels; Reactive Oxygen Species | 2007 |
Adenosinergic cardioprotection: multiple receptors, multiple pathways.
Topics: Adenosine; Aged; Aging; Animals; Humans; Ischemic Preconditioning, Myocardial; Myocardial Reperfusion Injury; Myocardium; Receptors, Purinergic P1; Signal Transduction | 2007 |
Physiological roles for adenosine and adenosine 5'-triphosphate in the nervous system.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Aging; Animals; Behavior; Biological Transport; Brain; Humans; Lesch-Nyhan Syndrome; Muscular Dystrophies; Nervous System; Nervous System Physiological Phenomena; Neurons; Neurotransmitter Agents; Phosphates | 1981 |
Aging and hormone-sensitive lipolysis: reconciling the literature.
Topics: Adenosine; Aging; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Rats; Rats, Inbred Strains | 1994 |
Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors.
Topics: Adenosine; Aging; Animals; Homeostasis; Nerve Endings; Nervous System Physiological Phenomena; Neuronal Plasticity; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, Purinergic P1 | 2001 |
Ontogeny of adenosine production and degradation and its implications in neonatal cerebral blood flow regulation.
Topics: Adenosine; Aging; Cerebrovascular Circulation; Child; Child, Preschool; Humans; Infant; Infant, Newborn | 1989 |
4 trial(s) available for adenosine and Aging
| Article | Year |
|---|---|
Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adult; Aging; Alkaline Phosphatase; Female; Gene Expression Regulation, Enzymologic; Humans; Infant, Newborn; Inosine; Male | 2013 |
Administration of high-dose continuous infusion interleukin-2 to patients age 70 or over.
Topics: Adenosine; Aged; Aged, 80 and over; Aging; Capillary Leak Syndrome; Famotidine; Hemodynamics; Humans; Immunotherapy; Infusions, Intravenous; Interleukin-2; Kidney Neoplasms; Killer Cells, Lymphokine-Activated; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Melanoma; Time Factors; Treatment Outcome | 2005 |
Impaired modulation of sympathetic alpha-adrenergic vasoconstriction in contracting forearm muscle of ageing men.
Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Aged; Aging; Clonidine; Forearm; Hand Strength; Humans; Male; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Sympatholytics; Tyramine; Vasoconstriction | 2005 |
The effect of adenosine on the reduced heart rate response to exercise in the elderly.
Topics: Adenosine; Aged; Aging; Anti-Arrhythmia Agents; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
165 other study(ies) available for adenosine and Aging
| Article | Year |
|---|---|
Adenosine protects D-galactose induced alterations in rat model of aging via attenuating neurochemical profile and redox status.
Topics: Acetylcholinesterase; Adenosine; Aging; Animals; Anti-Anxiety Agents; Antioxidants; Galactose; Malondialdehyde; Maze Learning; Memory Disorders; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Rats; Serotonin | 2022 |
Cell Differentiation and Aging Lead To Up-Regulation of FTO, While the ALKBH5 Protein Level Was Stable During Aging but Up-Regulated During in vitro-Induced Cardiomyogenesis.
Topics: Adenosine; Aging; AlkB Homolog 5, RNA Demethylase; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Cell Differentiation; Embryonic Development; Female; Male; Mice; RNA; Up-Regulation | 2023 |
Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing.
Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Antinematodal Agents; Carotid Body; Chemoreceptor Cells; Female; Gene Expression Regulation; Male; Rats; Rats, Wistar; Suramin; Triazines; Triazoles | 2019 |
T1-11, an adenosine derivative, ameliorates aging-related behavioral physiology and senescence markers in aging mice.
Topics: Adenosine; Aging; Animals; Cellular Senescence; Cognitive Dysfunction; Disease Models, Animal; Galactose; Gastrodia; Hippocampus; Humans; Male; Mice; Neurogenesis; Neurons; Oxidative Stress; Reactive Oxygen Species | 2020 |
Age-related muscle loss - novel target identified.
Topics: Adenosine; Aging; Humans; Obesity; Receptor, Adenosine A2B; Sarcopenia | 2020 |
Adenosine and Metabotropic Glutamate Receptors Are Present in Blood Serum and Exosomes from SAMP8 Mice: Modulation by Aging and Resveratrol.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Exosomes; Male; Mice; Receptor, Adenosine A1; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Resveratrol | 2020 |
Impact of Age on the Functional Evaluation of Intermediate Coronary Stenoses With Instantaneous Wave-Free Ratio and Fractional Flow Reserve.
Topics: Adenosine; Aged; Aging; Coronary Angiography; Coronary Stenosis; Female; Fractional Flow Reserve, Myocardial; Humans; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Vasodilator Agents | 2021 |
Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Cellular Senescence; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Inosine; Mice; Phosphorylation; Xanthine | 2020 |
The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes.
Topics: Adenosine; Aging; Animals; Cell Differentiation; Female; HEK293 Cells; HeLa Cells; Humans; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mouse Embryonic Stem Cells; Myocytes, Cardiac | 2020 |
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer's disease.
Topics: Adenosine; Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Drosophila; Drosophila Proteins; Humans; Methylation; Methyltransferases; Mice; Neurodegenerative Diseases; RNA Stability | 2021 |
Impact of aging on the effects of intracoronary adenosine, peak hyperemia and its duration during fractional flow reserve assessment.
Topics: Adenosine; Aged; Aging; Female; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Male; Middle Aged; Vasodilator Agents | 2021 |
m
Topics: Adenosine; Aging; Animals; Cellular Senescence; DNA Methylation; Genome; Methyltransferases; Mice; NF-kappa B; RNA, Messenger | 2021 |
The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging.
Topics: 3' Untranslated Regions; Adenosine; Aging; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Case-Control Studies; Cell Line; Down-Regulation; Female; Gene Silencing; Granulosa Cells; Humans; Methylation; Models, Biological; Ovary; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; RNA Stability; RNA, Messenger; Up-Regulation | 2021 |
Resveratrol Modulates and Reverses the Age-Related Effect on Adenosine-Mediated Signalling in SAMP8 Mice.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Aging; Animals; Cell Membrane; Gene Expression Regulation; Male; Metabolome; Mice; Receptors, Purinergic P1; Resveratrol; Signal Transduction; Weight Gain | 2019 |
Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength.
Topics: Adenosine; Aging; Animals; In Vitro Techniques; Male; Models, Biological; Neocortex; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Adenosine A1; Somatosensory Cortex; Synapses; Synaptic Transmission | 2013 |
Loss of ectonucleotidases from the coronary vascular bed after ischemia-reperfusion in isolated rat heart.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Triphosphatases; Aging; Animals; Antigens, CD; Apyrase; Coronary Vessels; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Nucleotidases; Phosphoric Diester Hydrolases; Pyrophosphatases; Rats, Wistar; Reperfusion Injury | 2013 |
In vitro anti-platelet potency of ticagrelor in blood samples from infants and children.
Topics: Adenosine; Adult; Aging; Blood Platelets; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newborn; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ticagrelor; Treatment Outcome | 2015 |
The role of adenosine in the maturation of sleep homeostasis in rats.
Topics: Adenosine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Electroencephalography; Electromyography; Evoked Potentials; Homeostasis; Preoptic Area; Prosencephalon; Rats; Rats, Sprague-Dawley; Sleep; Sleep Deprivation; Wakefulness | 2017 |
Regulation of protein kinase C-epsilon and its age-dependence.
Topics: Adenosine; Aging; Animals; Caveolin 3; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Male; Mitochondria; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Myocardium; Phosphatidylinositol 3-Kinases; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering | 2017 |
Effects of inhibitory amino acids on adenosine release in the mouse hippocampus.
Topics: Adenosine; Aging; Animals; Animals, Newborn; beta-Alanine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Oxygen; Serine | 2008 |
Role of oxidative stress and adenosine nucleotides in the liver of aging rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Age Factors; Aging; Animals; Catalase; Dinoprostone; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances | 2010 |
Thermal nociception is decreased by hypocretin-1 and an adenosine A1 receptor agonist microinjected into the pontine reticular formation of Sprague Dawley rat.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Aging; Animals; Benzoxazoles; Hot Temperature; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Pain; Pain Measurement; Pons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reticular Formation; Time Factors; Urea | 2010 |
Age-related changes in carotid vascular responses to adenosine and nitric oxide in the rat: in vitro and in vivo studies.
Topics: Adenosine; Age Factors; Aging; Animals; Blood Pressure; Carotid Artery, Common; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Infusions, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Regional Blood Flow; Vasodilation; Vasodilator Agents | 2010 |
Age-related gene-specific changes of A-to-I mRNA editing in the human brain.
Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adult; Aged; Aged, 80 and over; Aging; Cerebral Cortex; Female; Humans; Inosine; Male; Middle Aged; Receptors, GABA-A; RNA Editing; Young Adult | 2010 |
Carotid body function in aged rats: responses to hypoxia, ischemia, dopamine, and adenosine.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Aging; Animals; Carotid Body; Cyclic AMP; Disease Models, Animal; Dopamine; Dopamine Antagonists; Hypoxia; Ischemia; Male; Pulmonary Ventilation; Rats; Rats, Wistar; Receptor, Adenosine A2A | 2011 |
Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Aged; Aging; Dexmedetomidine; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Ultrasonography, Doppler; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2011 |
Enhancement of LTP in aged rats is dependent on endogenous BDNF.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Aging; Animals; Animals, Newborn; Axons; Brain-Derived Neurotrophic Factor; Cognition; Electric Stimulation; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory; Memory Disorders; Organ Culture Techniques; Phosphorylation; Rats; Rats, Wistar | 2011 |
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Long-Term Potentiation; Male; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Triazoles; Xanthines | 2011 |
Neuromuscular transmission modulation by adenosine upon aging.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Miniature Postsynaptic Potentials; Neuromuscular Junction; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 2012 |
Reduced adenosine release from the aged mammalian heart.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adrenergic Antagonists; Aging; Animals; Heart; Hydrolases; Male; Myocardial Contraction; Perfusion; Rats; Rats, Inbred F344; S-Adenosylhomocysteine; Sodium Chloride; Tubercidin | 2012 |
Coupling of calcium homeostasis to axonal sodium in axons of mouse optic nerve.
Topics: 4-Aminopyridine; Action Potentials; Adenosine; Aging; Animals; Animals, Newborn; Axons; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Fluorescent Dyes; Homeostasis; Ionophores; Mice; Monensin; Optic Nerve; Ouabain; Potassium Channel Blockers; Sodium; Sodium-Calcium Exchanger; Veratridine | 2002 |
Aging impairs endothelium-dependent vasodilation in rat skeletal muscle arterioles.
Topics: Acetylcholine; Adenosine; Aging; Animals; Arterioles; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Inbred F344; Stress, Mechanical; Vasodilation; Vasodilator Agents | 2002 |
ATP-evoked calcium responses of radial glial (Müller) cells in the postnatal rabbit retina.
Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Benzofurans; Calcium; Calcium Signaling; Cell Count; Cell Differentiation; Cell Size; Fluorescent Dyes; Imidazoles; In Vitro Techniques; Magnesium; Neuroglia; Potassium; Pyridoxal Phosphate; Rabbits; Retina; Stem Cells | 2002 |
NTP pattern of avian embryonic red cells: role of RNA degradation and AMP deaminase/5'-nucleotidase activity.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Adrenergic beta-Antagonists; Aging; AMP Deaminase; Animals; Chick Embryo; Cytidine Triphosphate; Erythrocytes; Fetal Blood; Hyperoxia; Oxyhemoglobins; RNA; Time Factors; Uridine Triphosphate | 2003 |
Adenosine receptor subtypes mediating coronary vasodilation in rat hearts.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Coronary Vessels; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Vasodilation | 2003 |
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Aging; Alkaloids; Animals; Arrhythmias, Cardiac; Benzophenanthridines; Coronary Circulation; Decanoic Acids; Diazoxide; DNA Primers; Female; Gene Expression; Heart; Hydroxy Acids; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Organ Size; Phenanthridines; Receptor, Adenosine A1; Vasodilator Agents | 2003 |
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiology; Excitatory Postsynaptic Potentials; Hippocampus; Isoproterenol; Male; Neurons; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles; Xanthines | 2003 |
STUDIES IN VITRO ON SINGLE BEATING HEART CELLS. V. CHANGES IN ADENOSINE-TRIPHOSPHATE-INDUCED CONTRACTIONS OF EXTRACTED MODELS.
Topics: Adenosine; Adenosine Triphosphate; Aging; Cell Biology; Connective Tissue; Glycerol; Heart; In Vitro Techniques; Myocardium; Pharmacology; Polyphosphates; Rats; Research; Tissue Culture Techniques; Trypsin | 1964 |
Effects of AT1 receptor block begun late in life on normal cardiac aging in rats.
Topics: Adenosine; Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Coronary Vessels; Exercise Tolerance; Heart; Hypertrophy, Left Ventricular; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Tetrazoles; Tibia; Vascular Resistance; Vasodilation | 2003 |
Aging-related changes in myocardial purine metabolism and ischemic tolerance.
Topics: Adenosine; Aging; Animals; Female; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Purines | 2003 |
The diurnal rhythm of adenosine levels in the basal forebrain of young and old rats.
Topics: Adenosine; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Circadian Rhythm; Electroencephalography; Microdialysis; Prosencephalon; Rats; Receptors, Purinergic P1; Sleep | 2004 |
Patent ductus arteriosus remodels cardiac sensory neuronal chemotransduction.
Topics: Action Potentials; Adenosine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Chemoreceptor Cells; Disease Models, Animal; Ductus Arteriosus, Patent; Female; Heart Ventricles; Male; Mechanoreceptors; Neural Conduction; Nodose Ganglion; Physical Stimulation; Sensory Receptor Cells; Signal Transduction; Sodium Channel Blockers; Sus scrofa; Visceral Afferents | 2004 |
Ageing-related decline in adenosine A1 receptor binding in the rat brain: an autoradiographic study.
Topics: Adenosine; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Binding Sites; Brain; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Tissue Distribution; Tritium | 2004 |
In vitro platelet responsiveness to adenosine-mediated "preconditioning" is age-dependent.
Topics: Adenosine; Aging; Animals; Antihypertensive Agents; Models, Animal; Phenethylamines; Platelet Aggregation; Rabbits; Rats; Signal Transduction | 2005 |
Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Aging; Animals; Bicuculline; Biological Clocks; Brain; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, GABA-A; Respiratory Mechanics | 2006 |
Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Aging; Animals; Arteries; Cell Membrane; Cells, Cultured; Cholesterol; Chromatography, High Pressure Liquid; Docosahexaenoic Acids; Endothelium, Vascular; Fatty Acids; Fatty Acids, Unsaturated; Membrane Fluidity; Rats; Rats, Wistar | 2005 |
Adenosine A(3) receptor mediated coronary vasodilation in the rat heart: changes that occur with maturation.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Aging; Animals; Coronary Circulation; Coronary Vessels; Dihydropyridines; Heart; Male; Perfusion; Rats; Rats, Wistar; Receptor, Adenosine A3; Vasodilation | 2006 |
Age-related changes in adenosine metabolic enzymes in sleep/wake regulatory areas of the brain.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adenosine Kinase; Aging; Animals; Brain; Male; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sleep; Wakefulness | 2006 |
Factors affecting accuracy of ventricular volume and ejection fraction measured by gated tl-201 myocardial perfusion single photon emission computed tomography.
Topics: Adenosine; Age Distribution; Age Factors; Aging; Coronary Circulation; Echocardiography; Evaluation Studies as Topic; Exercise Test; Female; Heart Ventricles; Humans; Image Interpretation, Computer-Assisted; Linear Models; Male; Middle Aged; Prospective Studies; Reference Values; Reproducibility of Results; Research Design; Sex Characteristics; Sex Distribution; Sex Factors; Software; Thallium Radioisotopes; Time Factors; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents; Ventricular Function, Left | 2006 |
Adenosine A2A receptor modulation of juvenile female rat skeletal muscle microvessel permeability.
Topics: Adenine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aging; Animals; Arterioles; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation; Muscle, Skeletal; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A2B; RNA, Messenger; Serum Albumin; Triazines; Triazoles; Vasodilator Agents; Venules | 2006 |
Loss of vascular adenosine A1 receptors with age in the rat heart.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Age Factors; Aging; Animals; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Down-Regulation; Heart; Heart Rate; In Vitro Techniques; Male; Pertussis Toxin; Rats; Rats, Wistar; Receptor, Adenosine A1; Vasoconstriction; Vasodilation; Vasodilator Agents; Ventricular Function, Left; Xanthines | 2006 |
Influence of age on BDNF modulation of hippocampal synaptic transmission: interplay with adenosine A2A receptors.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Aging; Animals; Binding, Competitive; Brain-Derived Neurotrophic Factor; Down-Regulation; Excitatory Postsynaptic Potentials; Hippocampus; Male; Neural Pathways; Organ Culture Techniques; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, trkB; Synaptic Transmission; Up-Regulation | 2007 |
Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats.
Topics: Acetylcholine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Hippocampus; Male; Memory; Memory Disorders; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Synaptic Transmission; Vesicular Acetylcholine Transport Proteins | 2008 |
In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound.
Topics: Adenosine; Aging; Animals; Dose-Response Relationship, Drug; Echocardiography; Femoral Artery; Hindlimb; Hyperemia; Ischemia; Male; Nitric Oxide Synthase; Nitroglycerin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reproducibility of Results; Stress, Mechanical; Vasodilation; Vasodilator Agents | 2008 |
Inhibition of lipolysis by adenosine is potentiated with age.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Isoproterenol; Lipid Mobilization; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Differential adenosine sensitivity in fibroblasts from different age donors.
Topics: Adenosine; Adenosine Deaminase; Adult; Aged; Aging; Cell Division; Cells, Cultured; Child; Child, Preschool; Fetus; Fibroblasts; Growth Inhibitors; Humans; Male; RNA | 1980 |
Kallikrein-kinin system and adenosine metabolism system of blood and heart and their changes at hypothalamic-hypophyseal stimulation in rabbits of different age.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Arginine Vasopressin; Hypothalamo-Hypophyseal System; Kallikreins; Kininogens; Kinins; Myocardium; Nucleotidases; Rabbits | 1980 |
[3H]N6-(L-Phenylisopropyl) adenosine binding in brains from young and old rats.
Topics: Adenosine; Aging; Animals; Brain; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Adenosine 5'-triphosphate (ATP)-mediated stimulation and suppression of DNA synthesis in lymphoid cells. II. Suppressive effect of ATP on murine T-cell functions.
Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; DNA; Hemolytic Plaque Technique; Immunosuppressive Agents; In Vitro Techniques; Lymphoid Tissue; Mice; Mice, Inbred Strains; Mitogens; Spleen; T-Lymphocytes | 1983 |
Vasopressin and cardiovascular system in aging.
Topics: Adenosine; Adult; Aged; Aging; Animals; Cardiac Output; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Energy Metabolism; Heart Rate; Hemodynamics; Humans; Kallikreins; Kinins; Middle Aged; Myocardium; Rabbits; Rats; Vasoconstriction; Vasopressins | 1982 |
The regional concentrations of S-adenosyl-L-methionine, S-adenosyl-L-homocysteine, and adenosine in rat brain.
Topics: Adenosine; Aging; Animals; Brain; Brain Chemistry; Homocysteine; Male; Pineal Gland; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tissue Distribution | 1982 |
Enhancement of the responsiveness of the rat diaphragm by L-methionine and phospholipid methylation and their relationships to aging.
Topics: Adenosine; Aging; Animals; Diaphragm; Electric Stimulation; Methionine; Methyltransferases; Muscle, Smooth; Phospholipids; Phrenic Nerve; Rats; Rats, Inbred F344 | 1982 |
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.
Topics: Adenine; Adenosine; Aging; Amino Acids; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Carbohydrate Metabolism; Cerebrovascular Circulation; Choline; Rabbits | 1980 |
Effect of aging on myocardial perfusion reserve.
Topics: Adenosine; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Coronary Circulation; Coronary Vessels; Dipyridamole; Female; Heart; Hemodynamics; Humans; Male; Middle Aged; Oxygen Radioisotopes; Sex Factors; Tomography, Emission-Computed; Vasodilator Agents; Water | 1995 |
Modification of A1 and A2a adenosine receptor binding in aged striatum, hippocampus and cortex of the rat.
Topics: Adenosine; Aging; Animals; Cerebral Cortex; Corpus Striatum; Hippocampus; In Vitro Techniques; Male; Membranes; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Xanthines | 1995 |
Regulation of extracellular adenosine levels in the striatum of aging rats.
Topics: 2-Amino-5-phosphonovalerate; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Aging; Amino Acids; Animals; Corpus Striatum; Enzyme Inhibitors; Extracellular Space; Male; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tubercidin | 1995 |
G2 repair and aging: influence of donor age on chromosomal aberrations in human lymphocytes.
Topics: Adenosine; Adult; Aged; Aging; Caffeine; Cell Cycle; Child, Preschool; Chromosome Aberrations; DNA Repair; Female; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Niacinamide | 1993 |
Calcium signaling of glial cells along mammalian axons.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aniline Compounds; Animals; Animals, Newborn; Axons; Calcium; Electric Stimulation; Fluorescent Dyes; Glutamates; Glutamic Acid; Kinetics; Microscopy, Fluorescence; Models, Neurological; Neuroglia; Neurons; Optic Nerve; Signal Transduction; Tetrodotoxin; Xanthenes | 1993 |
The role of adenosine in promoting cardiac beta-adrenergic subsensitivity in aging humans.
Topics: Adenosine; Adult; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Norepinephrine; Posture; Purinergic P1 Receptor Antagonists; Renin; Theophylline | 1995 |
Urinary excretion of nucleosides varies with age and protein metabolism.
Topics: Adenosine; Adolescent; Aging; Child; Child, Preschool; Humans; Nucleosides; Phenylketonurias; Proteins; Pseudouridine | 1995 |
Effects of neonatal exposure to caffeine on adenosine A1 receptor ontogeny using autoradiography.
Topics: Adenosine; Administration, Oral; Aging; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Cerebellum; Female; Hippocampus; Humans; Infant, Newborn; Infant, Premature; Male; Neurons; Organ Specificity; Pyramidal Cells; Rats; Receptors, Purinergic P1; Thalamus; Tritium | 1994 |
Characterization of adenosine receptors in a model of cultured neurons from rat forebrain.
Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Antihypertensive Agents; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Female; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenethylamines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Tritium | 1994 |
Cyclic AMP, early response gene expression, and DNA synthesis in rat smooth muscle cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta; Cell Division; Culture Media, Serum-Free; Cyclic AMP; DNA; Gene Expression Regulation; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley | 1994 |
Adenosine inhibition of beta-adrenergic induced responses in aged hearts.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Adrenergic beta-Antagonists; Aging; Animals; Coronary Vessels; Cyclic AMP; Extracellular Space; Heart; In Vitro Techniques; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphorylases; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1993 |
Age-related loss of mRNA encoding adenosine A2 receptor in the rat striatum.
Topics: Adenosine; Aging; Animals; Autoradiography; Biomarkers; Corpus Striatum; Enkephalins; Histocytochemistry; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Oligonucleotide Probes; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger | 1993 |
Selective changes of neurotransmitter receptors in middle-aged gerbil brain.
Topics: Adenosine; Aging; Animals; Autoradiography; Benzazepines; Brain; Dizocilpine Maleate; Gerbillinae; Isradipine; Male; Muscimol; Naloxone; Quinuclidinyl Benzilate; Receptors, Neurotransmitter; Tissue Distribution | 1993 |
Postnatal changes in receptor-mediated rabbit gastric smooth muscle relaxation.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Rabbits; Receptors, Adrenergic; Stomach; Vasoactive Intestinal Peptide; Weaning | 1993 |
Characterization and ontogeny of P1-purinoceptors on rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Animals, Newborn; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Muscle, Smooth; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic; Tetrodotoxin; Vas Deferens; Vasodilator Agents; Xanthines | 1993 |
Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Drug Interactions; Heart; Isoproterenol; Male; Membranes; Myocardium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Purinergic P1; Stimulation, Chemical; Tritium; Xanthines | 1996 |
Age-related characterization of atrial adenosine A1 receptor activation: direct effects on chronotropic and inotropic function in the Fischer 344 rat.
Topics: Adenosine; Aging; Animals; Atrial Function; Atrial Function, Left; Atrial Function, Right; Binding Sites; Heart Rate; Male; Myocardial Contraction; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sinoatrial Node; Tritium; Xanthines | 1996 |
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colforsin; Cyclic AMP; Heart Ventricles; Isoproterenol; Male; Molecular Sequence Data; Rabbits; Stimulation, Chemical; Therapeutic Equivalency | 1996 |
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
Topics: Adenosine; Aging; Animals; Coronary Vessels; Drug Synergism; Heart; Isoproterenol; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Triazoles; Veins; Xanthines | 1996 |
Impact of aging on adenosine levels, A1/A2 responses, arrhythmogenesis, and energy metabolism in rat heart.
Topics: Adenosine; Aging; Animals; Cardiovascular Agents; Energy Metabolism; Heart; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1996 |
The effects of age on the release of adenine nucleosides and nucleotides from rat caudal artery.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Aging; Animals; Arteries; Blood Pressure; Body Weight; Cricetinae; Endothelium, Vascular; Female; Methoxamine; Purine Nucleosides; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Tail | 1995 |
ATP catabolism and adenosine generation during ischemia in the aging heart.
Topics: Adenosine; Adenosine Triphosphate; Aging; Animals; Cardiovascular Agents; Glycogen; Male; Myocardial Ischemia; Rats; Rats, Inbred F344 | 1996 |
Integration of vascular, contractile and metabolic responses to hypoxia: effects of maturation and adenosine.
Topics: Adenosine; Aging; Animals; Coronary Circulation; Coronary Vessels; Energy Metabolism; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Myocardial Contraction; Myocardium; Rabbits; Theophylline | 1996 |
Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine.
Topics: 2-Chloroadenosine; Adenosine; Aging; Animals; Animals, Newborn; Cardiovascular System; Hypoxia; Respiration; Swine; Theophylline | 1996 |
Development of muscarinic potassium current in fetal and neonatal rat heart.
Topics: Acetylcholine; Adenosine; Aging; Animals; Animals, Newborn; Cells, Cultured; Embryonic and Fetal Development; Female; Fetal Heart; Heart; Membrane Potentials; Potassium Channels; Pregnancy; Rats | 1997 |
Distribution and postnatal ontogeny of adenosine A2A receptors in rat brain: comparison with dopamine receptors.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Autoradiography; Benzazepines; Brain; Gene Expression Regulation, Developmental; Organ Specificity; Phenethylamines; Raclopride; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Salicylamides; Tritium | 1997 |
Effects of adenosine and isoprenaline in left atria from both neonatal and middle-aged noninsulin-dependent diabetic rat models.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heart Atria; In Vitro Techniques; Insulin; Isoproterenol; Male; Myocardial Contraction; Rats; Streptozocin; Triglycerides | 1997 |
Presynaptic modulation of glutamate release targets different calcium channels in rat cerebrocortical nerve terminals.
Topics: Adenosine; Aging; Aminobutyrates; Animals; Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Egtazic Acid; Exocytosis; Glutamic Acid; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Phorbol Esters; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Spider Venoms; Synaptosomes | 1997 |
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation.
Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1998 |
Effect of aging on A1-adenosine receptor-mediated inhibition of norepinephrine release in the rat heart.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Heart; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Synaptosomes; Theophylline | 1998 |
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Xanthines | 1998 |
Age-related alteration of the adenosine/dopamine balance in the rat striatum.
Topics: Adenosine; Aging; Animals; Antihypertensive Agents; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Antagonists; Male; Phenethylamines; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Salicylamides; Tritium | 1998 |
A comparison of the adenosine-mediated synaptic inhibition in the CA3 area of immature and adult rat hippocampus.
Topics: Adenosine; Aging; Animals; Bicuculline; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Xanthines | 1998 |
Long-term supplementation with a high cholesterol diet decreases the release of ATP from the caudal artery in aged rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Arteries; Blood Pressure; Body Weight; Cholesterol; Cholesterol, Dietary; Fatty Acids, Unsaturated; Female; In Vitro Techniques; Norepinephrine; Rats; Rats, Wistar; Tail; Triglycerides | 1998 |
Adenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart.
Topics: Adenosine; Aging; Animals; Cardioplegic Solutions; Heart Arrest, Induced; Ischemic Preconditioning, Myocardial; Magnesium; Myocardial Reperfusion Injury; Potassium; Rabbits; Vasodilator Agents | 1998 |
Ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat distal colon.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Autoradiography; Binding Sites; Binding, Competitive; Colon; Male; Muscle Contraction; Muscle Development; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P1; Subcellular Fractions; Vasodilator Agents; Xanthines | 1999 |
Hypotension induced by exercise is associated with enhanced release of adenyl purines from aged rat artery.
Topics: Adenine Nucleotides; Adenosine; Aging; Animals; Arteries; Blood Pressure; Cholesterol; Fatty Acids; Female; Hypotension; Myocardium; Nitrates; Nitrites; Nucleosides; Physical Conditioning, Animal; Purines; Rats; Rats, Wistar | 1999 |
Effect of aging on myocardial adenosine production, adenosine uptake and adenosine kinase activity in rats.
Topics: Adenosine; Adenosine Kinase; Aging; Animals; Carbon Radioisotopes; Heart; Inosine; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Thioinosine | 1999 |
Striatal A2A adenosine receptors differentially regulate spontaneous and K+-evoked glutamate release in vivo in young and aged rats.
Topics: Adenosine; Aging; Animals; Aspartic Acid; Extracellular Space; Glutamic Acid; Male; Microdialysis; Neostriatum; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1 | 1999 |
Aminophylline alters the core temperature response to acute hypoxemia in newborn and older guinea pigs.
Topics: Adenosine; Aging; Aminophylline; Animals; Animals, Newborn; Body Temperature; Guinea Pigs; Hypoxia; Injections, Intraperitoneal; Phosphodiesterase Inhibitors | 1999 |
Increase in the number, G protein coupling, and efficiency of facilitatory adenosine A2A receptors in the limbic cortex, but not striatum, of aged rats.
Topics: Adenosine; Aging; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Dentate Gyrus; GTP-Binding Proteins; Kinetics; Limbic System; Male; Organ Specificity; Phenethylamines; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Tritium | 1999 |
Effect of aging on the negative chronotropic and anti-beta-adrenergic actions of adenosine in the rat heart.
Topics: Adenosine; Adrenergic beta-Antagonists; Aging; Animals; Cardiovascular Agents; Colforsin; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male; Myocardium; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1 | 1999 |
Cross talk between A(1) and A(2A) adenosine receptors in the hippocampus and cortex of young adult and old rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aging; Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Hippocampus; In Vitro Techniques; Male; Phenethylamines; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptic Membranes; Triazines; Triazoles; Xanthines | 1999 |
Age-related changes in A(1)-adenosine receptor-mediated bradycardia.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Bradycardia; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Receptors, Purinergic P1; Tritium | 2000 |
Effect of adenosine A2A receptor stimulation on GABA release from the striatum of young and aged rats in vivo.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Corpus Striatum; gamma-Aminobutyric Acid; Male; Microdialysis; Phenethylamines; Protein Isoforms; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1 | 1999 |
Age-dependent changes in adenosine A1 receptor and uptake site binding in the mouse brain: an autoradiographic study.
Topics: Adenosine; Aging; Animals; Autoradiography; Binding Sites; Brain; Mice; Mice, Inbred C57BL; Radioligand Assay; Receptors, Purinergic P1; Thioinosine | 2000 |
Tonic adenosine neuromodulation is preserved in motor nerve endings of aged rats.
Topics: Acetylcholine; Adenosine; Aging; Animals; Electric Stimulation; Male; Motor Neurons; Nerve Endings; Neurotransmitter Agents; Phrenic Nerve; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 2000 |
Effects of cyclopentyladenosine on isoproterenol response in adult and senescent cardiac tissue from Fischer 344 rats.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Cardiotonic Agents; Electric Stimulation; Heart; Heart Atria; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta; Xanthines | 2000 |
Mechanism of decreased adenosine protection in reperfusion injury of aging rats.
Topics: Adenosine; Aging; Animals; Cardiotonic Agents; Coronary Circulation; Heart; Heart Rate; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Ornithine; Penicillamine; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; S-Nitroso-N-Acetylpenicillamine; Time Factors; Ventricular Function, Left | 2000 |
Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats.
Topics: Adenosine; Age Factors; Aging; Animals; Aspartic Acid; Glutamic Acid; Male; Neostriatum; Neurons; Neuroprotective Agents; Potassium; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Time Factors; Triazoles | 2000 |
Modification of adenosine modulation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia; In Vitro Techniques; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 2000 |
Parallel modification of adenosine extracellular metabolism and modulatory action in the hippocampus of aged rats.
Topics: 5'-Nucleotidase; Acetylcholine; Adenosine; Adenosine Triphosphate; Aging; Animals; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Synaptosomes | 2001 |
Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans.
Topics: Adenosine; Adult; Aged; Aged, 80 and over; Aging; Coronary Circulation; Dipyridamole; Female; Heart; Humans; Hyperemia; Male; Middle Aged; Reference Values; Sex Characteristics; Tomography, Emission-Computed; Vasodilation | 2001 |
Age-related changes in adenosine-mediated relaxation of coronary and aortic smooth muscle.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Potassium Chloride; Rats; Rats, Wistar; Receptors, Purinergic P1; Signal Transduction; Vasodilation; Vasodilator Agents | 2001 |
Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Cell Count; Cell Degranulation; Cromolyn Sodium; Immunohistochemistry; Lung; Mast Cells; Mice; Mice, Transgenic; Receptors, Purinergic P1; Tolonium Chloride | 2001 |
Ontogenetic profile of ecto-ATPase activity in rat hippocampal and caudate nucleus synaptic plasma membrane fractions.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Aging; Animals; Caudate Nucleus; Cell Fractionation; Cell Membrane; Extracellular Space; Hippocampus; Male; Purines; Rats; Rats, Wistar | 2001 |
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury.
Topics: Adenosine; Aging; Animals; Diazoxide; Diglycerides; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors; Vasodilator Agents | 2001 |
Adenosine A2A, 5-HT1A and 5-HT7 receptor in neonatally pregnenolone-treated rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Aging; Animals; Animals, Newborn; Antihypertensive Agents; Binding, Competitive; Cerebral Cortex; Disease Models, Animal; Dopamine; Female; Male; Mental Disorders; Phenethylamines; Pregnancy; Pregnenolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sex Characteristics; Synaptic Transmission | 2001 |
Agonist-specific maturation of GIRK current responses in acutely isolated pyramidal neurons of rat neocortex.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Baclofen; Cellular Senescence; Electric Conductivity; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; Neocortex; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Serotonin | 2002 |
Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues.
Topics: Adenine; Adenine Nucleotides; Adenosine; Aging; Animals; Binding, Competitive; Carrier Proteins; Cattle; Chromatography, Agarose; Chromatography, DEAE-Cellulose; Cyclic AMP; Histones; Hydrogen-Ion Concentration; Liver; Molecular Weight; Protein Kinases; Rats; Trypsin | 1976 |
Vascular adenylate cyclase: role of age and guanine nucleotide activation.
Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Aorta; Cyclic AMP; Guanine Nucleotides; Guanosine Triphosphate; Isoproterenol; Male; Mesenteric Arteries; Prostaglandins E; Rats | 1977 |
Age-dependent enzymatic poly (A) metabolism in quail oviduct.
Topics: Adenosine; Aging; Animals; Avidin; Coturnix; Dactinomycin; Female; Oviducts; Poly A; Polynucleotide Adenylyltransferase; Progesterone; Ribonucleases; RNA, Messenger; Uridine | 1979 |
Cow red blood cells. III. Postnatal adaptation of energy metabolism in the calf red blood cells.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Glucose; Cattle; Dihydroxyacetone; Energy Metabolism; Erythrocytes; Female; Glyceraldehyde; Glycolysis; Inosine; Lactates; Ribose | 1979 |
Adenosine receptors, cyclic AMP accumulation, and DNA-synthesis in aortic smooth muscle cell cultures of adult and neonatal rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic | 1992 |
Decrease in cold tolerance of aged rats caused by the enhanced endogenous adenosine activity.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Body Temperature Regulation; Cold Temperature; Lysine; Male; Neck Muscles; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1992 |
Age related alterations in the response of the pial arterioles to adenosine in the rat.
Topics: Adenosine; Aging; Animals; Arterioles; Barium; Barium Compounds; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Male; Pia Mater; Rats; Rats, Inbred F344; Regional Blood Flow | 1992 |
Endogenous adenosine contributes to hypoxic synaptic depression in hippocampus from young and aged rats.
Topics: Adenosine; Aging; Animals; Cell Hypoxia; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Nitrogen; Rats; Rats, Inbred F344; Synapses; Theophylline | 1992 |
Ontogeny of surfactant secretion in type II pneumocytes from fetal, newborn, and adult rats.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Animals, Newborn; Female; In Vitro Techniques; Ionomycin; Kinetics; Lung; Male; Phospholipids; Pregnancy; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Terbutaline; Tetradecanoylphorbol Acetate | 1992 |
Age-related alterations in the arterial microvasculature of skeletal muscle.
Topics: Adenosine; Aging; Animals; Arterioles; Male; Muscles; Norepinephrine; Rats; Rats, Inbred F344; Vasoconstriction; Vasodilation | 1992 |
Induction of metallothionein in rats.
Topics: Adenosine; Aging; Animals; Catecholamines; Glucocorticoids; Hormones; Liver; Metallothionein; Metals; Peptides; Rats; Tetradecanoylphorbol Acetate; Xanthines | 1991 |
Radioligand binding to adenosine receptors and adenosine uptake sites in different brain regions of normal and narcoleptic dogs.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Cataplexy; Dogs; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Membranes; Narcolepsy; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic; Thioinosine; Xanthines | 1991 |
Rapid effects of hypoxia on the cerebrospinal fluid levels of adenosine and related metabolites in newborn and one-month-old piglets.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Gas Analysis; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Swine | 1991 |
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.
Topics: Adenosine; Aging; Animals; Calcium; Coronary Vessels; Guinea Pigs; Inosine; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Veins | 1990 |
Evidence for the involvement of cyclic GMP in adenosine-induced, age-dependent vasodilatation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Receptors, Purinergic; Vasodilation | 1990 |
Effects of age and adenosine in the modulation of insulin action on rat adipocyte metabolism.
Topics: Adenosine; Adipose Tissue; Aging; Animals; Dose-Response Relationship, Drug; Insulin; Isoproterenol; Lipid Metabolism; Lipolysis; Male; Rats; Rats, Inbred Strains | 1990 |
Interstitial transudate purines in normoxic and hypoxic immature and mature rabbit hearts.
Topics: Adenosine; Aging; Animals; Exudates and Transudates; Hemodynamics; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Myocardium; Oxygen Consumption; Rabbits | 1990 |
Ontogeny of adenosine response in guinea pig heart and aorta.
Topics: Adenosine; Aging; Animals; Aorta; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Osmolar Concentration; Perfusion | 1990 |
Effects of uric acid and caffeine on A1 adenosine receptor binding in developing rat brain.
Topics: Adenosine; Aging; Animals; Binding, Competitive; Brain; Caffeine; Male; Oxonic Acid; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Uric Acid | 1990 |
Inotropic response to DPI 201-106 in the failing human heart.
Topics: Adenosine; Adult; Aged; Aging; Calcium; Carbachol; Electric Stimulation; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Contraction; Papillary Muscles; Piperazines; Receptors, Adrenergic, beta | 1989 |
Aging increases adenosine and inosine release by human fibroblast cultures.
Topics: Adenosine; Aging; Cells, Cultured; Fibroblasts; Humans; Inosine | 1989 |
S-adenosylmethionine, S-adenosylhomocysteine and adenosine system. Age-dependent availability in rat brain.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Brain; Homocysteine; In Vitro Techniques; Kinetics; Male; Membranes; Methyltransferases; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine | 1989 |
Vessel reactivity and prejunctional modulatory changes in the portal vein of mature spontaneously hypertensive rats.
Topics: 2-Chloroadenosine; Adenosine; Aging; Animals; Blood Vessels; Electric Stimulation; Hypertension; In Vitro Techniques; Norepinephrine; Portal Vein; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic; Sympathetic Nervous System | 1989 |
Accumulation of adenosine 3',5'-monophosphate in slices of rat cerebral cortex induced by alpha-adrenergic agonists. I. Responses to methoxamine and norepinephrine in adult and neonatal tissue.
Topics: Adenosine; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Cerebral Cortex; Cyclic AMP; Drug Interactions; In Vitro Techniques; Isoproterenol; Methoxamine; Norepinephrine; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1987 |
Ontogeny of adenosine 3',5'-monophosphate metabolism in guinea pig cerebral cortex. II. Development of responses to L-glutamate in the presence of adenosine or histamine.
Topics: Adenosine; Aging; Animals; beta-Alanine; Calcium; Cerebral Cortex; Cyclic AMP; Gestational Age; Glutamates; Glutamic Acid; Guinea Pigs; Histamine; Potassium Chloride | 1987 |
Myocardial blood flow in left ventricular hypertrophy developing in young and adult dogs.
Topics: Adenosine; Aging; Animals; Aorta; Cardiomegaly; Coronary Circulation; Dogs; Hemodynamics; Ligation | 1986 |
Ontogeny of adenosine 3',5'-monophosphate metabolism in rabbit cerebral cortex. Development of responses to histamine, norepinephrine, adenosine, and glutamate.
Topics: Adenosine; Aging; Animals; Cerebral Cortex; Cyclic AMP; Drug Synergism; Glutamates; Histamine; Norepinephrine; Rabbits | 1987 |
Ontogenetic appearance of the adenosine receptor precedes N-protein coupling in rat forebrain.
Topics: Adenosine; Aging; Animals; Binding Sites; Binding, Competitive; Frontal Lobe; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1987 |
Metabolic hyperemia is reduced in adult vs. immature guinea pig hearts.
Topics: Adenosine; Aging; Animals; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Norepinephrine; Oxygen; Oxygen Consumption; Phentolamine; Reference Values | 1988 |
Purinergic modulation of cortical acetylcholine release is decreased in aging rats.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Caffeine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Parietal Lobe; Rats; Rats, Inbred Strains | 1988 |
Vasoactive compound effects on autoregulating versus nonautoregulating intestinal and renal circulations in young swine.
Topics: Adenosine; Aging; Animals; Heart Rate; Histamine; Homeostasis; In Vitro Techniques; Jejunum; Kidney; Norepinephrine; Perfusion; Regional Blood Flow; Renal Circulation; Swine; Vasodilator Agents | 1988 |
Effect of age and day time on the adenosine modulation of basal and insulin-stimulated glucose transport in rat adipocytes.
Topics: Adenosine; Aging; Animals; Biological Transport, Active; Circadian Rhythm; Glucose; In Vitro Techniques; Insulin; Male; Rats; Rats, Inbred Strains | 1988 |
Age-related changes in the response to vasoconstrictor and dilator agents in isolated beagle coronary arteries.
Topics: Acetylcholine; Adenosine; Aging; Angiotensin II; Animals; Coronary Vessels; Dogs; Epoprostenol; Female; Histamine; In Vitro Techniques; Male; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 1987 |
Adenosine uptake and [3H]nitrobenzylthioinosine binding in developing rat brain.
Topics: Adenosine; Aging; Animals; Binding Sites; Brain; Cerebellum; Cerebral Cortex; Hypothalamus; Inosine; Male; Rats; Rats, Inbred Strains; Superior Colliculi; Thioinosine | 1987 |
Evidence for adenosine adenosinedeaminase lymphocyte system impairment in ageing.
Topics: Adenosine; Adenosine Deaminase; Aged; Aging; Concanavalin A; Humans; Lymphocyte Activation; Lymphocytes; Middle Aged; Nucleoside Deaminases | 1987 |
Responsiveness to vasoconstrictor and dilator agents of senescent beagle cerebral arteries.
Topics: Adenosine; Aging; Animals; Basilar Artery; Cerebral Arteries; Dogs; Epoprostenol; Female; Histamine; In Vitro Techniques; Isoproterenol; Male; Nicotine; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 1986 |
Alterations with age of the response to vasodilator agents in isolated mesenteric arteries of the beagle.
Topics: Acetylcholine; Adenosine; Aging; Animals; Dogs; Endothelium; Epoprostenol; Female; Histamine; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Potassium; Vasodilator Agents | 1986 |
Altered endothelial modulation of vascular tone in aging and hypertension.
Topics: Adenosine; Aging; Animals; Blood Vessels; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelium; Hypertension; Isoproterenol; Muscle Tonus; Nitro Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride; Vasodilation | 1987 |
Effect of development on coronary vasodilator reserve in the isolated guinea pig heart.
Topics: Adenosine; Aging; Animals; Body Weight; Capillaries; Coronary Circulation; Coronary Vessels; Guinea Pigs; Heart; Homeostasis; Hyperemia; Nitroprusside; Organ Size; Perfusion; Pressure; Vasodilation | 1985 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Carbon Radioisotopes; Catecholamines; Cerebral Cortex; Cyclic AMP; Drug Synergism; Female; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phentolamine; Pregnancy; Propranolol; Rats; Receptors, Adrenergic | 1973 |
Isoprenylation of transfer ribonucleic acid.
Topics: Adenosine; Aging; Alkenes; Animals; Carbon Isotopes; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gas; Chromatography, Ion Exchange; Female; Kinetics; Liver; Pregnancy; RNA, Transfer; Serine; Spectrophotometry, Ultraviolet | 1973 |
Inhibition of 3-phosphoglycerate dehydrogenase from Pisum sativum by purine nucleotides.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Alcohol Oxidoreductases; Binding Sites; Glyceric Acids; Guanosine Triphosphate; Magnesium; Organophosphorus Compounds; Plants; Purine Nucleotides; Serine | 1973 |