Page last updated: 2024-08-24

adenosine and Ache

adenosine has been researched along with Ache in 145 studies

Research

Studies (145)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (8.28)	18.7374
1990's	48 (33.10)	18.2507
2000's	48 (33.10)	29.6817
2010's	29 (20.00)	24.3611
2020's	8 (5.52)	2.80

Authors

Authors	Studies
Chen, L; Cheng, L; Hu, Z; Li, J; Shi, Z; Xu, G; Zhang, S; Zheng, L	1
Ding, B; Gao, D; Hu, B; Xiao, L; Zhang, Y; Zhao, Q	1
Hao, JW; Hu, WP; Li, Q; Li, XM; Liu, TT; Qiao, WL; Qiu, CY; Wei, S	1
Jacobson, KA; Pradhan, B; Pramanik, A; Wen, Z	1
Al-Saraireh, YM; Alsalem, M; Cherchi, F; Haddad, M; Madae'en, S	1
Chen, S; Guo, Y; Song, Y; Wang, LK; Zhang, RY; Zhao, JG; Zhao, L; Zhu, BF	1
Adakudugu, EA; Ameyaw, EO; Anokwah, D; Biney, RP; Henneh, IT; Obese, E; Woode, E	1
Cao, JL; Hao, LY; Jin, T; Liu, X; Pan, Z; Shen, W; Sun, ML; Tao, Y; Xie, L; Xue, ZY; Yang, XX; Ye, XC; Zhang, M; Zhang, Q; Zhou, H	1
Bellieni, CV; Petraglia, F; Vannuccini, S	1
Hsieh, CL; Hsu, HC; Lin, YW; Yen, LT	1
Fischer, L; Morais, RN; Sardi, NF; Tobaldini, G	1
Hsieh, CL; Huang, CP; Liao, HY; Lin, YW	2
Ceruti, S; Magni, G	1
Arruda, BR; da Silva, AV; Lopes, SC; Morais, TC; Rao, VS; Rios, JB; Santos, FA; Trevisan, MT	1
Herrero, JF; Ramos-Zepeda, G	1
Herrero, JF; Herrero-Zorita, C; Ramos-Zepeda, GA	1
André, E; Asth, L; Calo', G; de P Soares-Rachetti, V; Gavioli, EC; Guerrini, R; Holanda, AD; Santos, AR	1
Huang, YG; Shen, L; Xu, L; Zhang, YG	1
Adamah-Biassi, EB; Almonte, AG; Blagovechtchenski, E; Bonin, KD; Budygin, EA; Grinevich, VP; Weiner, JL	1
Fedorova, OV; Shabano, PD; Zarubina, IV	1
Jun, IG; Park, JY	1
Benedek, G; Horvath, G; Kekesi, G; Nagy, E; Tuboly, G	1
Herrala, A; Sowa, NA; Taylor-Blake, B; Twomey, MA; Vihko, P; Voikar, V; Zylka, MJ	1
Connor, M	1
Antunes, C; Böhmer, AE; Elisabetsky, E; Lara, DR; Porciúncula, LO; Schallenberger, C; Schmidt, AP; Souza, DO	1
Baghdoyan, HA; Lydic, R; Wang, W	1
Ribeiro, JA; Sebastião, AM	1
Burnstock, G	1
Kelz, MB; Moore, JT	1
Baghdoyan, HA; Lydic, R; Watson, CJ; Watson, SL	1
Sowa, NA; Taylor-Blake, B; Zylka, MJ	1
Borghi, V; Kowalska, M; Nalepa, I; Pavone, F; Przewłocka, B; Roman, A; Vetulani, J	1
Bekar, L; Chen, JF; Chen, M; Fujita, T; Goldman, N; Han, X; Jensen, TK; Liu, W; Nedergaard, M; Pei, Y; Peng, W; Schnermann, J; Takano, T; Tieu, K; Wang, F; Xu, Q	1
Cressey, D	1
Fredholm, BB; Hao, JX; Li, L; Schulte, G; Wiesenfeld-Hallin, Z; Xu, XJ	1
Sereda, MJ	1
Kim, WM; Lee, HG; Park, CH; Yoon, MH	1
Street, SE; Zylka, MJ	1
Boison, D	2
Hahm, KD; Jeong, SM; Kim, YK; Lee, C; Leem, JG; Park, PH; Shin, JW; Song, JG	1
Guillot, TS; Sowa, NA; Street, SE; Taylor-Blake, B; Vihko, P; Walsh, PL; Wightman, RM; Zylka, MJ	1
Gao, ZG; Jacobson, KA	1
Crea, F; Di Franco, A; Di Monaco, A; Lamendola, P; Lanza, GA; Nerla, R; Sestito, A; Tarzia, P; Valeriani, M; Virdis, D; Vollono, C	1
Gmiro, VE; Serdiuk, SE	1
Guan, L; Mu, Y; Quaglia, LA; Shih, MC; Tang, Q; Wang, C; Yang, L	1
Bastia, E; Bertorelli, R; Monopoli, A; Varani, K	1
Curry, R; Eisenach, JC; Hood, DD	3
Borghi, V; Ilona, O; Labuz, D; Maj, M; Pavone, F; Przewlocka, B	1
Arendt-Nielsen, L; Graven-Nielsen, T; Jansson, Y; Kristensen, JD; Mense, S; Segerdahl, M; Sollevi, A	1
Clark, AJ; Lynch, ME; Sawynok, J	1
Liu, XJ; Sawynok, J	1
GOMAHR, H	1
MOULTON, R; SPECTOR, WG; WILLOUGHBY, DA	1
Abo-Salem, OM; Bilkei-Gorzo, A; Filipek, B; Hayallah, AM; Müller, CE; Zimmer, A	1
DeLander, GE; Fredholm, BB; Molander, C; Robertson, B; Schulte, G; Shortland, P	1
Berglund, M; Eriksson, BE; Sadigh-Lindell, B; Sylvén, C	1
Inoue, K; Koizumi, S; Tsuda, M	1
Fujita, T; Kawasaki, Y; Kumamoto, E; Lao, LJ; Yang, K	1
Bantel, C; Childers, SR; Conklin, D; Eisenach, JC; Li, X	1
Fujita, T; Kumamoto, E; Yang, K	1
Allen, G; Aumeerally, N; Sawynok, J	1
Andreotti, N; Carrega, L; Devaux, C; Guieu, R; Jouirou, B; Martin-Eauclaire, MF; Peragut, JC; Pham, T; Regaya, I; Rochat, H; Sabatier, JM; Sauze, N; Vacher, H	1
Bae, HB; Choi, JI; Jeong, CY; Jeong, SW; Park, HC; Yoon, MH	1
Bouman, EA; Dagnelie, PC; Skrabanja, AT	1
Fukuda, K; Fukunaga, A; Hayashida, M	1
An, TH; Bae, HB; Choi, JI; Chung, SS; Chung, ST; Jeong, CY; Jeong, SW; Kim, CM; Kim, SJ; Yoo, KY; Yoon, MH	1
Fukuda, K; Fukunaga, A; Hanaoka, K; Hayashida, M; Ichinohe, T; Kaneko, Y; Mamiya, H; Sakurai, S	1
Sawynok, J	2
Buechler, NL; Eisenach, JC; Kim, SA; Martin, TJ; Porreca, F	1
Irnich, D; Lang, PM	1
Cappellacci, L; de Novellis, V; Franchetti, P; Grifantini, M; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Rossi, F; Stella, L; Vita, D	1
Benedek, G; Horvath, G; Kekesi, G; Tuboly, G	1
Diamond, I; Ferré, S; Goldberg, SR; Hourani, SM; Huang, ZL; Kitchen, I; Urade, Y; Yao, L	1
Azdad, K; d'Exaerde, Ade K; Dumont, H; Gall, D; Guntz, E; Pastijn, E; Schiffmann, SN; Sosnowski, M	1
Post, C	1
Chiariello, L; Crea, F; Crossman, DC; Gaspardone, A; Gioffrè, PA; Iamele, M; Pappagallo, M; Tomai, F; Versaci, F	1
Charest, J; Li, J; Marchand, S	1
Foster, AC; Miller, LP; Wiesner, JB	1
Arai, Y; Kisara, K; Nagaoka, H; Nakagawa, Y; Sakurada, S; Sakurada, T; Takeda, S	1
Chiariello, L; Crea, F; Gaspardone, A; Gioffrè, G; Gioffrè, PA; Iamele, M; Tomai, F; Versaci, F	1
Ekblom, A; Segerdahl, M; Sollevi, A	1
Chen, JY; Dafny, N; Qiao, JT; Xie, YF; Yang, SW; Zhang, ZH	1
Sylvén, C	1
Crea, F; Gaspardone, A; Gioffré, PA; Iamele, M; Pappagallo, M; Tomai, F	1
Ahlgren, SC; Levine, JD	1
Guieu, R	1
Belardinelli, L; Bertolet, BD; Franco, EA; Hill, JA; Kerensky, RA; Nichols, WW	1
Lee, YW; Yaksh, TL	1
Burnstock, G; Wood, JN	1
DeLander, GE; Keil, GJ	1
Acciavatti, A; Capecchi, PL; Cati, G; Ceccatelli, L; Colafati, M; de Lalla, A; Di Perri, T; Pasini, FL; Petri, S	1
Sollevi, A	1
Snyder, SH	1
Costentin, J; El Yacoubi, M; Heath, JK; Ledent, C; Parmentier, M; Pedrazzini, T; Schiffmann, SN; Vanderhaeghen, JJ; Vassart, G; Vaugeois, JM	1
Guieu, R; Guy, B; Pouget, J; Rochat, H; Sampiéri, F	1
Kemmotsu, O; Nakamura, I; Ohta, Y	1
Dickenson, AH; Kerr, NC; Reeve, AJ	1
Akimoto, T; Mashimoto, S; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M	1
Hao, JX; Sjölund, KF; Sollevi, A; von Heijne, M; Wiesenfeld-Hallin, Z; Xu, XJ	1
Cui, JG; Linderoth, B; Meyerson, BA; O'Connor, WT; Segerdahl, M; Sollevi, A; Stiller, CO; Yakhnitsa, V	1
Khandwala, H; Loomis, CW; Zhang, Z	1
Hao, JX; Sollevi, A; von Heijne, M; Wiesenfeld-Hallin, Z; Xu, XJ; Yu, W	1
Arnér, S	1
Bhagwat, SS; Jarvis, MF; Kowaluk, EA	1
Eisenach, JC; Lavand'homme, PM	1
Esser, MJ; Reid, AR; Sawynok, J	1
Arnér, S; Belfrage, M; Segerdahl, M; Sollevi, A	1
Dryden, C; Kinsella, J; Mansfield, MD; Rae, CP	1
Dafny, N; Kang, YM; Qiao, JT; Zhang, C; Zhao, Y	1
Eisenach, JC; Gomes, JA; Li, X; Pan, HL	1
Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ	1
Gebhart, GF; Su, X; Wachtel, RE	1
Aley, KO; Levine, JD; Messing, RO; Mochly-Rosen, D	1
Hazato, T; Inoue, M; Matsunaga, S; Ueda, H; Yamamoto, Y	1
Cook, SP; McCleskey, EW; Sutherland, SP	1
Eisenach, JC; Leung, E; Pan, HL; Xu, Z	1
Gyllenhammar, E; Nordfors, LO	1
Rosen, SD	1
Bantel, C; Chen, SR; Childers, SR; Eisenach, JC; Li, X; Tobin, JR	1
Han, BF; Qi, JS; Qiao, JT; Zhang, C	1
Bourgoin, S; Cesselin, F; Hamon, M; Mauborgne, A; Poliénor, H	1
Canković-Darracott, S; Chayen, J; Jenkins, BS; Malcolm, AD; Webb-Peploe, MM	1
Bleehen, T; Keele, CA	1
Heller, PH; Levine, JD; Taiwo, YO	1
Hayaishi, O; Horiguchi, S; Hyodo, M; Ito, S; Minami, T; Uda, R	1
De Koninck, Y; Henry, JL	1
Arndt, JO; Klement, W	1
Beermann, B; Jonzon, B; Kaijser, L; Sylvén, C	1
Belvedere, DA; Coyne, EP; Evans, RB; Spaccavento, LJ; Vande Streek, PR; Weiland, FL	1
Isbrucker, R; Reid, A; Sawynok, J	1
Aran, S; Proudfit, HK	2
Boyce, TM; Hixson, JB; Mahmarian, JJ; Staudacher, RA; Verani, MS	1
DeLander, GE; Wahl, JJ	1
Sawynok, J; Sweeney, MI	1
Sosnowski, M; Stevens, CW; Yaksh, TL	1
Sawynok, J; Sweeney, MI; White, TD	1
Horne, JJ; Lewis, DJ; Smith, PM; Watt, AH	1
Fredholm, BB; Jonzon, B; Kaijser, L; Sylvén, C	1
Juan, H; Lembeck, F	1

Reviews

23 review(s) available for adenosine and Ache

Article	Year
New paradigms in purinergic receptor ligand discovery. Neuropharmacology, 2023, 06-01, Volume: 230 Topics: Adenosine; Humans; Inflammation; Ligands; Pain; Purinergic P1 Receptor Antagonists; Receptors, Purinergic	2023
Adenosine Receptors as Potential Therapeutic Analgesic Targets. International journal of molecular sciences, 2023, Aug-24, Volume: 24, Issue:17 Topics: Adenosine; Analgesics; Humans; Ligands; Pain; Receptors, Purinergic P1	2023
Is fetal analgesia necessary during prenatal surgery? The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018, Volume: 31, Issue:9 Topics: Adenosine; Analgesia; Anesthesia; Arousal; Female; Fetal Blood; Fetus; Gestational Age; Humans; MEDLINE; Nervous System; Pain; Pain Management; Pregnancy; Pregnanolone; Prostaglandin D2	2018
The role of adenosine and P2Y receptors expressed by multiple cell types in pain transmission. Brain research bulletin, 2019, Volume: 151 Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Central Nervous System; Humans; Neuroglia; Neurons; Pain; Receptors, Purinergic; Receptors, Purinergic P2Y; Signal Transduction	2019
Regulatory effect of caffeine on the acute and the chronic pain and its possible mechanisms. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2014, Volume: 36, Issue:6 Topics: Adenosine; Caffeine; Central Nervous System Stimulants; Chronic Pain; Humans; Pain	2014
Adenosine receptors and the central nervous system. Handbook of experimental pharmacology, 2009, Issue:193 Topics: Adenosine; Aging; Animals; Brain; Brain-Derived Neurotrophic Factor; Humans; Neurotransmitter Agents; Pain; Receptors, Cannabinoid; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Sleep; Synaptic Transmission	2009
Purines and sensory nerves. Handbook of experimental pharmacology, 2009, Issue:194 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Central Nervous System; Ganglia, Sensory; Humans; Mechanotransduction, Cellular; Neural Pathways; Pain; Purines; Receptors, Purinergic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sensation Disorders; Sensory Receptor Cells; Viscera	2009
Modulators of nucleoside metabolism in the therapy of brain diseases. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:8 Topics: Adenosine; Adenosine Kinase; Analgesics; Animals; Anticonvulsants; Brain; Brain Diseases; Epilepsy; Gene Expression; Humans; Metabolic Networks and Pathways; Mice; Mice, Knockout; Neuroprotective Agents; Pain; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Schizophrenia; Signal Transduction; Sleep Wake Disorders	2011
Adenosine in the spinal cord and periphery: release and regulation of pain. Progress in neurobiology, 2003, Volume: 69, Issue:5 Topics: Adenosine; Afferent Pathways; Animals; Humans; Pain; Peripheral Nerves; Spinal Cord	2003
ATP- and adenosine-mediated signaling in the central nervous system: chronic pain and microglia: involvement of the ATP receptor P2X4. Journal of pharmacological sciences, 2004, Volume: 94, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Central Nervous System; Chronic Disease; Humans; Microglia; Pain; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Signal Transduction	2004
Potential value of adenosine 5'-triphosphate (ATP) and adenosine in anaesthesia and intensive care medicine. British journal of anaesthesia, 2005, Volume: 94, Issue:5 Topics: Adenosine; Adenosine Triphosphate; Anesthesia; Critical Care; Hemodynamics; Humans; Pain; Shock, Septic	2005
Clinical application of adenosine and ATP for pain control. Journal of anesthesia, 2005, Volume: 19, Issue:3 Topics: Acute Disease; Adenosine; Adenosine Triphosphate; Animals; Chronic Disease; Humans; Injections, Intravenous; Injections, Spinal; Pain; Pain, Postoperative	2005
Adenosine and ATP receptors. Handbook of experimental pharmacology, 2007, Issue:177 Topics: Adenosine; Analgesics; Animals; Humans; Pain; Receptors, Purinergic P1; Receptors, Purinergic P2	2007
Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain. Progress in neurobiology, 2007, Volume: 83, Issue:5 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Basal Ganglia; Humans; Hypothalamus; Neural Pathways; Pain; Receptor, Adenosine A1; Receptor, Adenosine A2A; Sleep Wake Disorders; Substance-Related Disorders	2007
Adenosine as a neuromodulator in neurological diseases. Current opinion in pharmacology, 2008, Volume: 8, Issue:1 Topics: Adenosine; Adenosine Kinase; Alzheimer Disease; Animals; Brain Diseases; Brain Ischemia; Epilepsy; Humans; Huntington Disease; Pain; Parkinson Disease; Schizophrenia; Synaptic Transmission	2008
Regulation of endogenous adenosine levels in the CNS: potential for therapy in stroke, epilepsy and pain. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Adenosine; Animals; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Epilepsy; Homeostasis; Humans; Pain; Receptors, Purinergic P1	1994
Mechanisms of pain in angina pectoris--a critical review of the adenosine hypothesis. Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:5 Topics: Adenosine; Angina Pectoris; Humans; Pain	1993
Purinergic receptors: their role in nociception and primary afferent neurotransmission. Current opinion in neurobiology, 1996, Volume: 6, Issue:4 Topics: Adenosine; Adenosine Triphosphate; Afferent Pathways; Animals; Humans; Neurons, Afferent; Nociceptors; Pain; Receptors, Purinergic; Synaptic Transmission	1996
Adenosine for pain control. Acta anaesthesiologica Scandinavica. Supplementum, 1997, Volume: 110 Topics: Acute Disease; Adenosine; Analgesics; Analgesics, Opioid; Animals; Central Nervous System; Chronic Disease; Disease Models, Animal; Hot Temperature; Humans; Infusions, Intravenous; Injections, Intravenous; Injections, Spinal; Neurons, Afferent; Nociceptors; Pain; Peripheral Nerves; Pressure; Receptors, Cell Surface; Rodentia; Spinal Cord; Touch	1997
Adenosine receptor activation and nociception. European journal of pharmacology, 1998, Apr-17, Volume: 347, Issue:1 Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Humans; Nociceptors; Pain; Receptors, Purinergic P1	1998
Adenosine kinase inhibitors. Current pharmaceutical design, 1998, Volume: 4, Issue:5 Topics: Adenosine; Adenosine Kinase; Animals; Chemistry, Pharmaceutical; Enzyme Inhibitors; Humans; In Vitro Techniques; Inflammation; Pain; Wounds and Injuries	1998
Chemical mediators of pain due to tissue damage and ischemia. Progress in brain research, 2000, Volume: 129 Topics: Acetylcholine; Acid Sensing Ion Channels; Adenosine; Adenosine Triphosphate; Afferent Pathways; Animals; Bradykinin; Glutamic Acid; Heart; Humans; Lactic Acid; Membrane Proteins; Myocardial Ischemia; Nerve Tissue Proteins; Neurons, Afferent; Nociceptors; Pain; Potassium; Proton Pumps; Receptors, Purinergic P2; Signal Transduction; Sodium Channels	2000
The role of purines in nociception. Neuroscience, 1989, Volume: 32, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Central Nervous System; Pain; Second Messenger Systems	1989

Trials

14 trial(s) available for adenosine and Ache

Article	Year
Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology, 2002, Volume: 97, Issue:4 Topics: Adenosine; Administration, Topical; Adult; Aminophylline; Analgesics, Non-Narcotic; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hot Temperature; Humans; Hyperalgesia; Hypersensitivity; Infusions, Intravenous; Injections, Spinal; Male; Middle Aged; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists	2002
Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design. Pain, 2003, Volume: 103, Issue:1-2 Topics: Adenosine; Adult; Analgesics; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Infusions, Intravenous; Middle Aged; Neuralgia; Pain; Pain Measurement; Pain Threshold; Placebos; Sensation; Sensory Thresholds; Time; Time Factors; Treatment Outcome	2003
Role of adenosine and opioid-receptor mechanisms for pain in patients with silent myocardial ischemia or angina pectoris: a double-blind, placebo-controlled study. Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:6 Topics: Adenosine; Angina Pectoris; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Time Factors	2003
Substance P potentiates the algogenic effects of intraarterial infusion of adenosine. Journal of the American College of Cardiology, 1994, Volume: 24, Issue:2 Topics: Adenosine; Adult; Aged; Chest Pain; Coronary Vessels; Drug Synergism; Female; Humans; Iliac Artery; Infusions, Intra-Arterial; Male; Middle Aged; Pain; Pain Threshold; Substance P	1994
Effects of caffeine on analgesia from transcutaneous electrical nerve stimulation. The New England journal of medicine, 1995, Aug-03, Volume: 333, Issue:5 Topics: Adenosine; Adult; Caffeine; Double-Blind Method; Female; Humans; Male; Pain; Pain Measurement; Transcutaneous Electric Nerve Stimulation	1995
Muscular and cardiac adenosine-induced pain is mediated by A1 receptors. Journal of the American College of Cardiology, 1995, Volume: 25, Issue:1 Topics: Adenosine; Adult; Aged; Analgesics; Angina Pectoris; Dose-Response Relationship, Drug; Female; Humans; Iliac Artery; Infusions, Intra-Arterial; Male; Middle Aged; Muscular Diseases; Pain; Pain Measurement; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline	1995
The influence of adenosine, ketamine, and morphine on experimentally induced ischemic pain in healthy volunteers. Anesthesia and analgesia, 1994, Volume: 79, Issue:4 Topics: Adenosine; Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ischemia; Ketamine; Male; Morphine; Muscles; Pain; Single-Blind Method	1994
Analgesic effect of bamiphylline on pain induced by intradermal injection of adenosine. Pain, 1993, Volume: 53, Issue:2 Topics: Adenosine; Adult; Analgesics; Female; Humans; Injections, Intradermal; Male; Pain; Receptors, Purinergic; Sodium Chloride; Theophylline	1993
The safety and efficacy of intrathecal adenosine in patients with chronic neuropathic pain. Anesthesia and analgesia, 1999, Volume: 89, Issue:1 Topics: Adenosine; Adult; Chronic Disease; Female; Humans; Injections, Spinal; Male; Middle Aged; Pain	1999
Analgesic effect of adenosine on ischaemic pain in human volunteers. British journal of anaesthesia, 1999, Volume: 82, Issue:3 Topics: Adenosine; Analgesics; Arm; Cross-Over Studies; Double-Blind Method; Humans; Ischemia; Male; Pain; Tourniquets	1999
Phase I safety assessment of intrathecal injection of an American formulation of adenosine in humans. Anesthesiology, 2002, Volume: 96, Issue:1 Topics: Adenosine; Adult; Analgesics; Back Pain; Double-Blind Method; Female; Humans; Injections, Spinal; Leg; Male; Pain	2002
Preliminary efficacy assessment of intrathecal injection of an American formulation of adenosine in humans. Anesthesiology, 2002, Volume: 96, Issue:1 Topics: Adenosine; Adult; Analgesics; Capsaicin; Double-Blind Method; Female; Humans; Hyperalgesia; Injections, Spinal; Male; Middle Aged; Pain; Pain Threshold	2002
Reproduction of epigastric pain of duodenal ulceration by adenosine. British medical journal (Clinical research ed.), 1987, Jan-03, Volume: 294, Issue:6563 Topics: Adenosine; Adult; Aminophylline; Duodenal Ulcer; Humans; Male; Middle Aged; Pain; Pain Measurement	1987
Adenosine injection into the brachial artery produces ischaemia like pain or discomfort in the forearm. Cardiovascular research, 1988, Volume: 22, Issue:9 Topics: Adenosine; Adult; Brachial Artery; Forearm; Humans; Injections, Intra-Arterial; Ischemia; Male; Nitroglycerin; Pain; Regional Blood Flow; Vasodilation	1988

Other Studies

108 other study(ies) available for adenosine and Ache

Article	Year
In silico identification of A1 agonists and A2a inhibitors in pain based on molecular docking strategies and dynamics simulations. Purinergic signalling, 2023, Volume: 19, Issue:1 Topics: Adenosine; Humans; Molecular Docking Simulation; Pain; Receptor, Adenosine A1; Receptor, Adenosine A2A	2023
N6-Methyladenosine-induced miR-143-3p promotes intervertebral disc degeneration by regulating SOX5. Bone, 2022, Volume: 163 Topics: Adenosine; Apoptosis; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Methyltransferases; MicroRNAs; Pain; SOXD Transcription Factors; Tumor Necrosis Factor-alpha	2022
A1 Adenosine Receptor Activation Inhibits P2X3 Receptor-Mediated ATP Currents in Rat Dorsal Root Ganglion Neurons. Molecular neurobiology, 2022, Volume: 59, Issue:11 Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Analgesics; Animals; Colforsin; Ganglia, Spinal; Neurons; Pain; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2X3	2022
Electroacupuncture alleviates inflammatory pain via adenosine suppression and its mediated substance P expression. Arquivos de neuro-psiquiatria, 2020, Volume: 78, Issue:10 Topics: Adenosine; Animals; Electroacupuncture; Pain; Rats; Rats, Sprague-Dawley; Substance P	2020
Antinociceptive effect of the hydroethanolic leaf extract of Calotropis procera (Ait) R. Br. (Apocynaceae): Possible involvement of glutamatergic, cytokines, opioidergic and adenosinergic pathways. Journal of ethnopharmacology, 2021, Oct-05, Volume: 278 Topics: Adenosine; Analgesics; Analgesics, Opioid; Animals; Calotropis; Dose-Response Relationship, Drug; Ghana; Glutamic Acid; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Pain Threshold; Plant Extracts; Plant Leaves	2021
Methyltransferase-like 3 contributes to inflammatory pain by targeting TET1 in YTHDF2-dependent manner. Pain, 2021, 07-01, Volume: 162, Issue:7 Topics: Adenosine; Animals; Methyltransferases; Pain; RNA; RNA, Messenger	2021
Targeting ASIC3 for Relieving Mice Fibromyalgia Pain: Roles of Electroacupuncture, Opioid, and Adenosine. Scientific reports, 2017, 04-25, Volume: 7 Topics: Acid Sensing Ion Channels; Adenosine; Analgesics, Opioid; Animals; Electroacupuncture; Fibromyalgia; Ganglia, Spinal; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pain; Pain Management; Signal Transduction	2017
Nucleus accumbens mediates the pronociceptive effect of sleep deprivation: the role of adenosine A2A and dopamine D2 receptors. Pain, 2018, Volume: 159, Issue:1 Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Male; Motor Activity; Nociception; Nucleus Accumbens; Pain; Phenethylamines; Piribedil; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Dopamine D2; Sleep Deprivation; Sleep, REM; Triazoles	2018
Electroacupuncture Attenuates Induction of Inflammatory Pain by Regulating Opioid and Adenosine Pathways in Mice. Scientific reports, 2017, Nov-15, Volume: 7, Issue:1 Topics: Adenosine; Analgesics, Opioid; Animals; Astrocytes; Cyclooxygenase 2; Disease Models, Animal; Electroacupuncture; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Inflammation; Mice; NF-kappa B; Pain; Pain Management; Protein Kinase C-epsilon; Rats; Receptor for Advanced Glycation End Products; S100 Calcium Binding Protein beta Subunit; Signal Transduction; Spinal Cord Dorsal Horn	2017
Peripheral antinociceptive action of mangiferin in mouse models of experimental pain: role of endogenous opioids, K(ATP)-channels and adenosine. Pharmacology, biochemistry, and behavior, 2013, Volume: 110 Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Disease Models, Animal; Mice; Opioid Peptides; Pain; Potassium Channels; Xanthones	2013
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) and opioid receptors in spinal cord nociceptive reflexes. Life sciences, 2013, Aug-14, Volume: 93, Issue:5-6 Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Opioid; Reflex; Spinal Cord	2013
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes. Behavioural pharmacology, 2014, Volume: 25, Issue:8 Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord	2014
Central adenosine A1 and A2A receptors mediate the antinociceptive effects of neuropeptide S in the mouse formalin test. Life sciences, 2015, Jan-01, Volume: 120 Topics: Adenosine; Animals; Formaldehyde; Male; Mice; Neuropeptides; Nociception; Pain; Pain Measurement; Receptor, Adenosine A1; Receptor, Adenosine A2A	2015
Real time adenosine fluctuations detected with fast-scan cyclic voltammetry in the rat striatum and motor cortex. Journal of neuroscience methods, 2015, Dec-30, Volume: 256 Topics: Adenosine; Animals; Carbon; Carbon Fiber; Corpus Striatum; Electrochemical Techniques; Electrodes, Implanted; Male; Motor Cortex; Pain; Physical Stimulation; Rats, Long-Evans; Tail; Time	2015
[ANALGESIC EFFECT OF TROPALGIN ON THERMAL PAIN IN RATS WITH DIFFERENT PAIN THRESHOLDS]. Eksperimental'naia i klinicheskaia farmakologiia, 2015, Volume: 78, Issue:8 Topics: Adenosine; Analgesics; Animals; Burns; Dipyrone; Male; Pain; Rats; Rats, Wistar	2015
Electroacupuncture Attenuates CFA-induced Inflammatory Pain by suppressing Nav1.8 through S100B, TRPV1, Opioid, and Adenosine Pathways in Mice. Scientific reports, 2017, 02-13, Volume: 7 Topics: Acupuncture Analgesia; Adenosine; Analgesics, Opioid; Animals; Behavior, Animal; Biomarkers; Chromones; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Gene Deletion; Gene Expression; Gene Knockout Techniques; Glial Fibrillary Acidic Protein; Male; Mice; Morpholines; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Pain; Pain Management; Proto-Oncogene Proteins c-akt; S100 Calcium Binding Protein beta Subunit; Signal Transduction; Spinal Cord Dorsal Horn; TOR Serine-Threonine Kinases; TRPV Cation Channels; Xanthines	2017
The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation. Journal of Korean medical science, 2008, Volume: 23, Issue:4 Topics: Adenosine; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Pain; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Nerves; Xanthines	2008
The antinociceptive interaction of anandamide and adenosine at the spinal level. Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3 Topics: Adenosine; Analgesics; Animals; Arachidonic Acids; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Hot Temperature; Inflammation; Injections, Spinal; Male; Pain; Pain Measurement; Polyunsaturated Alkamides; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reaction Time	2009
Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. Neuron, 2008, Oct-09, Volume: 60, Issue:1 Topics: 5'-Nucleotidase; Acid Phosphatase; Adenosine; Animals; Ganglia, Spinal; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain; Pain Measurement; Protein Tyrosine Phosphatases; Receptor, Adenosine A1	2008
Allopurinol for pain relief: more than just crystal clearance? British journal of pharmacology, 2009, Volume: 156, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Allopurinol; Analgesics; Animals; Gout; Mice; Pain; Reactive Oxygen Species; Xanthine Oxidase	2009
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors. British journal of pharmacology, 2009, Volume: 156, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Allopurinol; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Glutamic Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrimidines; Triazoles; Uric Acid; Xanthine Oxidase; Xanthines	2009
Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice. The journal of pain, 2009, Volume: 10, Issue:8 Topics: Acetylcholine; Adenosine; Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Hot Temperature; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Neostigmine; Nicotine; Obesity; Pain; Pain Measurement; Pons; Time Factors	2009
Opiates, sleep, and pain: the adenosinergic link. Anesthesiology, 2009, Volume: 111, Issue:6 Topics: Adenosine; Analgesics, Opioid; Animals; Arousal; Brain Chemistry; Humans; Pain; Sleep	2009
Thermal nociception is decreased by hypocretin-1 and an adenosine A1 receptor agonist microinjected into the pontine reticular formation of Sprague Dawley rat. The journal of pain, 2010, Volume: 11, Issue:6 Topics: Adenosine; Adenosine A1 Receptor Agonists; Aging; Animals; Benzoxazoles; Hot Temperature; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Pain; Pain Measurement; Pons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reticular Formation; Time Factors; Urea	2010
Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-10, Volume: 30, Issue:6 Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; Cell Membrane; Ganglia, Spinal; Hydrolysis; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Nerve Endings; Nociceptors; Pain; Presynaptic Terminals; Receptor, Adenosine A1; Sciatic Nerve; Skin	2010
Changes induced by formalin pain in central alpha1-adrenoceptor density are modulated by adenosine receptor agonists. Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:5 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Autoradiography; Central Nervous System; Disease Models, Animal; Inflammation; Male; Mice; Nociceptors; Pain; Pain Measurement; Phenethylamines; Prazosin; Receptor, Adenosine A2A; Receptors, Adrenergic, alpha-1	2010
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nature neuroscience, 2010, Volume: 13, Issue:7 Topics: Acupuncture Analgesia; Adenosine; Afferent Pathways; Analysis of Variance; Animals; Disease Models, Animal; Mice; Nucleotidases; Pain; Pain Management; Peripheral Nervous System Diseases; Receptors, Purinergic P1; Sciatica; Statistics, Nonparametric	2010
Acupuncture for mice. Nature, 2010, Jun-03, Volume: 465, Issue:7298 Topics: Acupuncture Therapy; Adenosine; Animals; Caffeine; Humans; Mice; Models, Animal; Pain; Pain Management; Pentostatin; Placebo Effect; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2010
Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice. Neuroscience, 2010, Oct-27, Volume: 170, Issue:3 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Carrageenan; Female; Ganglia, Spinal; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Knockout; Pain; Pain Threshold; Phenethylamines; Receptor, Adenosine A2A; Sex Characteristics; Triazines; Triazoles	2010
Purines 2010: Adenine Nucleosides and Nucleotides in Biomedicine. IDrugs : the investigational drugs journal, 2010, Volume: 13, Issue:8 Topics: Adenine Nucleotides; Adenosine; Anemia, Sickle Cell; Bone and Bones; Cystic Fibrosis; Drug Design; Drugs, Investigational; Humans; Neoplasms; Neurodegenerative Diseases; Pain; Pulmonary Fibrosis; Receptors, Purinergic; Signal Transduction	2010
Roles of adenosine and serotonin receptors on the antinociception of sildenafil in the spinal cord of rats. Yonsei medical journal, 2010, Volume: 51, Issue:6 Topics: Adenosine; Analgesics; Animals; Cyclic GMP; Dihydroergocristine; Injections, Spinal; Male; Pain; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Serotonin; Sildenafil Citrate; Spinal Cord; Sulfones; Vasodilator Agents	2010
Emerging roles for ectonucleotidases in pain-sensing neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:1 Topics: 5'-Nucleotidase; Acid Phosphatase; Adenosine; Adenosine A1 Receptor Agonists; Animals; Ganglia, Spinal; GPI-Linked Proteins; Humans; Nociceptors; Nucleotidases; Pain; Protein Tyrosine Phosphatases; Receptor, Adenosine A1	2011
Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats. Anesthesia and analgesia, 2011, Volume: 112, Issue:6 Topics: 4-Aminopyridine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Humans; Hyperalgesia; Injections, Spinal; Male; Neurons; Pain; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Spinal Nerves	2011
PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine. Molecular pain, 2011, Oct-19, Volume: 7 Topics: 5'-Nucleotidase; Acid Phosphatase; Adenosine; Adenosine Monophosphate; Animals; Dipyridamole; Ganglia, Spinal; Male; Mice; Mice, Knockout; Nociception; Nucleotides; Pain; Protein Tyrosine Phosphatases; Receptor, Adenosine A1; Synaptic Transmission; Tubercidin	2011
Emerging adenosine receptor agonists: an update. Expert opinion on emerging drugs, 2011, Volume: 16, Issue:4 Topics: Adenosine; Arrhythmias, Cardiac; Clinical Trials as Topic; Diabetes Mellitus; Drugs, Investigational; Humans; Inflammation; Molecular Structure; Pain; Purinergic P1 Receptor Agonists; Treatment Outcome	2011
Coronary microvascular function and cortical pain processing in patients with silent positive exercise testing and normal coronary arteries. The American journal of cardiology, 2012, Jun-15, Volume: 109, Issue:12 Topics: Adenosine; Aged; Blood Flow Velocity; Case-Control Studies; Cold Temperature; Coronary Angiography; Coronary Circulation; Coronary Vessels; Echocardiography; Echocardiography, Doppler; Evoked Potentials, Somatosensory; Exercise Test; False Positive Reactions; Female; Humans; Male; Microcirculation; Microvascular Angina; Middle Aged; Pain; Vasodilator Agents	2012
[Peripheral acting mediators pain and analgesia potentiate the central analgesic action of fentanyl and dipyrone]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Analgesia; Analgesics; Animals; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Fentanyl; Glutamic Acid; Male; Pain; Phenylephrine; Rats; Rats, Wistar	2012
Effectiveness of myocardial contrast echocardiography quantitative analysis during adenosine stress versus visual analysis before percutaneous therapy in acute coronary pain: a coronary artery TIMI grading comparing study. Journal of biomedicine & biotechnology, 2012, Volume: 2012 Topics: Acute Coronary Syndrome; Adenosine; Adult; Aged; Analysis of Variance; Coronary Angiography; Echocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Pain; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index	2012
Effects of A(1) and A(2A) adenosine receptor ligands in mouse acute models of pain. Neuroscience letters, 2002, Aug-16, Volume: 328, Issue:3 Topics: Acute Disease; Adenosine; Animals; Behavior, Animal; Ligands; Mice; Nociceptors; Pain; Pain Measurement; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazoles	2002
Formalin-induced pain and mu-opioid receptor density in brain and spinal cord are modulated by A1 and A2a adenosine agonists in mice. Brain research, 2002, Nov-29, Volume: 956, Issue:2 Topics: Adenosine; Animals; Autoradiography; Central Nervous System; Fixatives; Formaldehyde; Male; Mice; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Periaqueductal Gray; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Opioid, mu; Receptors, Purinergic P1; Spinal Cord; Thalamus	2002
Experimental pain by ischaemic contractions compared with pain by intramuscular infusions of adenosine and hypertonic saline. European journal of pain (London, England), 2003, Volume: 7, Issue:1 Topics: Adenosine; Adult; Exercise; Female; Humans; Injections, Intramuscular; Ischemia; Male; Muscle Contraction; Muscle, Skeletal; Nociceptors; Pain; Pain Measurement; Pain Threshold; Pressure; Saline Solution, Hypertonic; Vasodilator Agents	2003
[Influence of adenosine on the action of dimethylaminophenyldimethylpyrazolon]. Arzneimittel-Forschung, 1956, Volume: 6, Issue:11 Topics: Adenosine; Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Pain	1956
Histamine release and pain production by xanthosine and related compounds. British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:3 Topics: Adenosine; Animals; Cats; Female; Guanosine; Guinea Pigs; Histamine; Histamine Release; Humans; Ileum; Injections, Intradermal; Inosine; Male; Nucleosides; Nucleotides; Pain; Ribonucleosides; Xanthine; Xanthines	1957
Antinociceptive effects of novel A2B adenosine receptor antagonists. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Analgesia; Animals; Caffeine; Drug Synergism; Male; Mice; Morphine; Pain	2004
Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations. Neuroscience, 2003, Volume: 121, Issue:4 Topics: Adenosine; Afferent Pathways; Biomarkers; Glycoproteins; Lectins; Ligation; Nerve Fibers, Unmyelinated; Nerve Tissue Proteins; Nociceptors; Pain; Posterior Horn Cells; Receptor, Adenosine A1; Receptors, AMPA; Rhizotomy; Spinal Nerve Roots; Synaptic Transmission	2003
Modulation by adenosine of Adelta and C primary-afferent glutamatergic transmission in adult rat substantia gelatinosa neurons. Neuroscience, 2004, Volume: 125, Issue:1 Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Glutamine; Male; Neurons, Afferent; Organ Culture Techniques; Pain; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Substantia Gelatinosa; Synaptic Transmission	2004
Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain. Anesthesiology, 2004, Volume: 100, Issue:4 Topics: Adenosine; Administration, Oral; Allosteric Regulation; Animals; Drug Tolerance; Male; Pain; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Nerves; Thiophenes; Xanthines	2004
Adenosine inhibits GABAergic and glycinergic transmission in adult rat substantia gelatinosa neurons. Journal of neurophysiology, 2004, Volume: 92, Issue:5 Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Colforsin; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons; Pain; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Potassium Channels; Rats; Substantia Gelatinosa; Synaptic Transmission	2004
Glutamate-evoked release of adenosine and regulation of peripheral nociception. Neuroscience, 2004, Volume: 127, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Citrates; Conditioning, Psychological; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Gliosis; Glutamic Acid; Male; Microglia; Neural Inhibition; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Theophylline	2004
Small conductance calcium-activated K+ channels, SkCa, but not voltage-gated K+ (Kv) channels, are implicated in the antinociception induced by CGS21680, a A2A adenosine receptor agonist. Life sciences, 2004, Dec-10, Volume: 76, Issue:4 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Apamin; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Pain Threshold; Phenethylamines; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Scorpion Venoms	2004
Analysis of interactions between serotonin and gabapentin or adenosine in the spinal cord of rats. Pharmacology, 2005, Volume: 74, Issue:1 Topics: Adenosine; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord	2005
Evaluation of interaction between intrathecal adenosine and MK801 or NBQX in a rat formalin pain model. Pharmacology, 2005, Volume: 75, Issue:3 Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Formaldehyde; Injections, Spinal; Male; N-Methylaspartate; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley	2005
The characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil. Anesthesia and analgesia, 2006, Volume: 103, Issue:4 Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Heart Rate; Infusions, Intravenous; Isoflurane; Male; Nociceptors; Pain; Pain Measurement; Piperidines; Rabbits; Remifentanil; Respiration	2006
Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics. Anesthesiology, 2007, Volume: 106, Issue:2 Topics: Adenosine; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Fentanyl; Heroin; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Male; Methadone; Morphine; Neuralgia; Pain; Rats; Rats, Inbred F344; Self Administration	2007
[Adenosine for treatment of ischemic pain in thromboangiitis obliterans. A case report]. Schmerz (Berlin, Germany), 2007, Volume: 21, Issue:3 Topics: Adenosine; Adult; Analgesics; Female; Humans; Ischemia; Pain; Pain Measurement; Thromboangiitis Obliterans; Treatment Outcome	2007
The antinociceptive effect of 2-chloro-2'-C-methyl-N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat. Pain, 2007, Volume: 131, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Agonists; Analgesics; Animals; Dose-Response Relationship, Drug; Hyperalgesia; Male; Pain; Pain Threshold; Rats; Rats, Wistar	2007
Antinociceptive interactions of triple and quadruple combinations of endogenous ligands at the spinal level. Brain research, 2007, Jun-25, Volume: 1155 Topics: Adenosine; Agmatine; Analgesics; Animals; Area Under Curve; Disease Models, Animal; Drug Combinations; Injections, Spinal; Kynurenic Acid; Ligands; Male; Motor Activity; Oligopeptides; Pain; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Spinal Cord	2007
Expression of adenosine A 2A receptors in the rat lumbar spinal cord and implications in the modulation of N-methyl-d-aspartate receptor currents. Anesthesia and analgesia, 2008, Volume: 106, Issue:6 Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Blotting, Western; Glycine; Lumbosacral Region; Membrane Potentials; N-Methylaspartate; Pain; Patch-Clamp Techniques; Phenethylamines; Posterior Horn Cells; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Substantia Gelatinosa	2008
Antinociceptive effects in mice after intrathecal injection of 5'-N-ethylcarboxamide adenosine. Neuroscience letters, 1984, Oct-26, Volume: 51, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Injections, Spinal; Male; Mice; Pain; Reaction Time; Receptors, Cell Surface; Receptors, Purinergic; Spinal Cord	1984
Theophylline-induced nociceptive behavioral response in mice: possible indirect interaction with spinal N-methyl-D-aspartate receptors. Neurochemistry international, 1993, Volume: 22, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Male; Mice; Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Spinal Cord; Substance P; Theophylline	1993
Morphine and norepinephrine-induced antinociception at the spinal level is mediated by adenosine. Neuroreport, 1994, Jul-21, Volume: 5, Issue:12 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminophylline; Animals; Female; Male; Morphine; Naloxone; Norepinephrine; Pain; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Serotonin; Spinal Cord; Time Factors	1994
Mechanical hyperalgesia in streptozotocin-diabetic rats. Neuroscience, 1993, Volume: 52, Issue:4 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylate Cyclase Toxin; Animals; Diabetes Mellitus, Experimental; Dideoxyadenosine; Dinoprostone; GTP-Binding Proteins; Guanosine Diphosphate; Hyperalgesia; Indomethacin; Male; Mechanoreceptors; Pain; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Thionucleotides; Virulence Factors, Bordetella	1993
[Painful legs and involuntary movements of the toes. Indirect therapeutic role of adenosine]. Presse medicale (Paris, France : 1983), 1993, Feb-06, Volume: 22, Issue:4 Topics: Adenosine; Aged; Electric Stimulation Therapy; Female; Humans; Leg; Movement Disorders; Pain; Pain Management; Toes	1993
Selective attenuation by N-0861 (N6-endonorboran-2-yl-9-methyladenine) of cardiac A1 adenosine receptor-mediated effects in humans. Circulation, 1996, May-15, Volume: 93, Issue:10 Topics: Adenine; Adenosine; Aged; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Humans; Male; Middle Aged; Norbornanes; Pain; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	1996
Pharmacology of the spinal adenosine receptor which mediates the antiallodynic action of intrathecal adenosine agonists. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3 Topics: Adenosine; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Male; Pain; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Spinal Cord	1996
Altered sensory behaviors in mice following manipulation of endogenous spinal adenosine neurotransmission. European journal of pharmacology, 1996, Sep-19, Volume: 312, Issue:1 Topics: Adenosine; Animals; Deoxyadenosines; Grooming; Male; Mice; Neurotransmitter Agents; Pain; Spinal Cord; Substance P; Theophylline	1996
Experimental model of short-time exercise-induced preconditioning in POAD patients. Angiology, 1997, Volume: 48, Issue:6 Topics: Adenosine; Adenosine Triphosphate; Aged; Blood Viscosity; Calcium; Exercise Therapy; Exercise Tolerance; Female; Hemorheology; Humans; Intermittent Claudication; Ischemic Preconditioning, Myocardial; Leg; Male; Middle Aged; Neutrophil Activation; Neutrophils; Pain; Peripheral Vascular Diseases; Physical Fitness; Walking	1997
Adenosine receptors. Knockouts anxious for new therapy. Nature, 1997, Aug-14, Volume: 388, Issue:6643 Topics: Adenosine; Animals; Caffeine; Drug Therapy; Mice; Mice, Knockout; Pain; Receptors, Purinergic P1	1997
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature, 1997, Aug-14, Volume: 388, Issue:6643 Topics: Adenosine; Aggression; Animals; Blood Pressure; Brain; Caffeine; Cloning, Molecular; Heart Rate; Humans; Hypertension; Male; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Phenethylamines; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Restriction Mapping; Sequence Homology, Amino Acid	1997
Adenosine in painful legs and moving toes syndrome. Clinical neuropharmacology, 1994, Volume: 17, Issue:5 Topics: Adenosine; Adult; Aged; Female; Humans; Leg; Male; Middle Aged; Neuromuscular Diseases; Nociceptors; Pain; Pain Management; Pain Threshold; Peripheral Nervous System Diseases; Reflex; Restless Legs Syndrome; Syndrome; Toes	1994
Characterization of adenosine receptors mediating spinal sensory transmission related to nociceptive information in the rat. Anesthesiology, 1997, Volume: 87, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Dose-Response Relationship, Drug; Female; Male; Pain; Rats; Rats, Wistar; Receptors, Purinergic P1; Reflex, Monosynaptic; Spinal Cord; Theophylline	1997
Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist. Journal of neurophysiology, 1998, Volume: 79, Issue:3 Topics: Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Kynurenic Acid; Male; Morphine; Naloxone; Nerve Fibers; Neurons; Pain; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch	1998
Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats. Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1 Topics: Adenosine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Caffeine; Carbamazepine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Pain; Physical Stimulation; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors	1998
Intrathecal administration of the adenosine A1 receptor agonist R-phenylisopropyl adenosine reduces presumed pain behaviour in a rat model of central pain. Neuroscience letters, 1998, Feb-27, Volume: 243, Issue:1-3 Topics: Adenosine; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Spinal; Nociceptors; Pain; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Vasodilator Agents	1998
Modulation of spinal pain mechanisms by spinal cord stimulation and the potential role of adjuvant pharmacotherapy. Stereotactic and functional neurosurgery, 1997, Volume: 68, Issue:1-4 Pt 1 Topics: Adenosine; Animals; Baclofen; Behavior, Animal; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Models, Animal; Electric Stimulation Therapy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Pain; Pain Management; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Purinergic P1; Spinal Cord; Touch; Treatment Outcome	1997
Inhibition of strychnine-allodynia is mediated by spinal adenosine A1- but not A2-receptors in the rat. Brain research, 1998, Oct-12, Volume: 808, Issue:1 Topics: Adenosine; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Spinal; Male; Pain; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Strychnine; Xanthines	1998
Reduced anti-allodynic effect of the adenosine A1-receptor agonist R-phenylisopropyladenosine on repeated intrathecal administration and lack of cross-tolerance with morphine in a rat model of central pain. Anesthesia and analgesia, 1998, Volume: 87, Issue:6 Topics: Adenosine; Analgesics; Analgesics, Opioid; Animals; Chronic Disease; Drug Tolerance; Female; Injections, Spinal; Morphine; Pain; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries	1998
Pain analysis in prediction of treatment outcome. Acta anaesthesiologica Scandinavica. Supplementum, 1998, Volume: 113 Topics: Adenosine; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dose-Response Relationship, Drug; Drug Administration Schedule; Forecasting; Humans; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Phentolamine; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympatholytics; Treatment Outcome	1998
Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. Pain, 1999, Volume: 80, Issue:1-2 Topics: Adenosine; Analgesics, Opioid; Animals; Deoxyadenosines; Dipyridamole; Drug Synergism; Injections, Spinal; Ligation; Male; Morphine; Neuritis; Pain; Pain Measurement; Physical Stimulation; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Spinal Nerves	1999
Peripheral antinociceptive action of amitriptyline in the rat formalin test: involvement of adenosine. Pain, 1999, Volume: 80, Issue:1-2 Topics: Adenosine; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Caffeine; Dose-Response Relationship, Drug; Male; Pain; Pain Measurement; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Glutamate; Receptors, Histamine; Receptors, Opioid	1999
Endogenous adenosine involved in the mediation of spinal antinociception produced by stimulating locus coeruleus. Life sciences, 1999, Volume: 65, Issue:5 Topics: Adenosine; Aminophylline; Animals; Electric Stimulation; Female; Locus Coeruleus; Male; Pain; Phentolamine; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Spinal Cord; Sympatholytics	1999
Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats. Anesthesiology, 1999, Volume: 91, Issue:4 Topics: Adenosine; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Ligation; Male; Nociceptors; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Spinal Nerve Roots	1999
Intrathecal adenosine does not relieve allodynia-like behavior in spinally injured rats. Neuroreport, 1999, Oct-19, Volume: 10, Issue:15 Topics: Adenosine; Animals; Behavior, Animal; Female; Injections, Spinal; Motor Activity; Neuroprotective Agents; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries	1999
Capsaicin sensitivity and voltage-gated sodium currents in colon sensory neurons from rat dorsal root ganglia. The American journal of physiology, 1999, Volume: 277, Issue:6 Topics: Action Potentials; Adenosine; Analgesics; Animals; Bradykinin; Capsaicin; Carbocyanines; Colon; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Fluorescent Dyes; Ganglia, Spinal; Histamine; Ion Channel Gating; Male; Neurons, Afferent; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Sodium; Sodium Channels; Tetrodotoxin	1999
Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jun-15, Volume: 20, Issue:12 Topics: Adenosine; Animals; Carrageenan; Dinoprostone; Enzyme Inhibitors; Hindlimb; Hyperalgesia; Inflammation; Isoenzymes; Male; Nociceptors; Pain; Phenethylamines; Protein Kinase C; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors	2000
Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine. Peptides, 2000, Volume: 21, Issue:8 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Analgesics, Opioid; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Morphine; Neurons, Afferent; Neuroprotective Agents; Oligopeptides; Pain; Pertussis Toxin; Piperidines; Protease Inhibitors; Purinergic Agonists; Thionucleosides; Time Factors; Virulence Factors, Bordetella	2000
Allosteric adenosine modulation to reduce allodynia. Anesthesiology, 2001, Volume: 95, Issue:2 Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Spinal; Male; Pain; Pain Measurement; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Nerves; Xanthines	2001
Systemic adenosine infusions alleviated neuropathic pain. Pain, 2001, Volume: 94, Issue:1 Topics: Adenosine; Adolescent; Analgesics; Humans; Infusions, Intravenous; Male; Metabolic Diseases; Pain	2001
The pathophysiology of cardiac syndrome X--a tale of paradigm shifts. Cardiovascular research, 2001, Volume: 52, Issue:2 Topics: 3-Iodobenzylguanidine; Adenosine; Coronary Disease; Dipyridamole; Heart Rate; Humans; Microvascular Angina; Pain; Pain Threshold; Sympathetic Nervous System	2001
Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding. Anesthesiology, 2002, Volume: 96, Issue:1 Topics: Adenosine; Analgesics; Animals; Injections, Spinal; Ligation; Male; Microdialysis; Pain; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Nerves; Xanthines	2002
ATP-sensitive potassium channels and endogenous adenosine are involved in spinal antinociception produced by locus coeruleus stimulation. Sheng li xue bao : [Acta physiologica Sinica], 2002, Apr-25, Volume: 54, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Electric Stimulation; Female; Injections, Spinal; Locus Coeruleus; Male; Pain; Potassium Channels; Rats; Rats, Wistar	2002
Adenosine receptor-mediated control of in vitro release of pain-related neuropeptides from the rat spinal cord. European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcitonin Gene-Related Peptide; Cholecystokinin; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Neuropeptides; Pain; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Substance P; Xanthines	2002
Biopsy evidence of left ventricular myocardial abnormality in patients with mitral-leaflet prolapse and chest pain. Lancet (London, England), 1979, May-19, Volume: 1, Issue:8125 Topics: Adenosine; Adenosine Triphosphatases; Adult; Female; Heart Ventricles; Histocytochemistry; Humans; Male; Middle Aged; Mitral Valve Prolapse; Monoamine Oxidase; Myocardium; Pain; Succinate Dehydrogenase; Succinates; Thorax	1979
Observations on the algogenic actions of adenosine compounds on the human blister base preparation. Pain, 1977, Volume: 3, Issue:4 Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blister; Calcium; Cyclic AMP; Humans; Jejunum; Muscle Tonus; Nerve Endings; Pain; Potassium; Rabbits; Skin	1977
Mediation of serotonin hyperalgesia by the cAMP second messenger system. Neuroscience, 1992, Volume: 48, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Analgesics; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Isomerism; Male; Nociceptors; Pain; Protein Kinase Inhibitors; Pyrrolidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Rolipram; Second Messenger Systems; Serotonin; Tetrahydronaphthalenes	1992
Allodynia evoked by intrathecal administration of prostaglandin F2 alpha to conscious mice. Pain, 1992, Volume: 50, Issue:2 Topics: Adenosine; Animals; Behavior, Animal; Dinoprost; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Pain; Reaction Time; Sympathomimetics	1992
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord. Neuroscience, 1992, Volume: 50, Issue:2 Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration	1992
Adenosine does not evoke pain from venous and paravascular nociceptors in the human. Cardiovascular research, 1992, Volume: 26, Issue:2 Topics: Adenosine; Blood Vessels; Electric Stimulation; Hand; Humans; Injections; Male; Nociceptors; Pain; Perfusion	1992
Nicotine enhances angina pectoris-like chest pain and atrioventricular blockade provoked by intravenous bolus of adenosine in healthy volunteers. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:6 Topics: Adenosine; Adult; Angina Pectoris; Drug Synergism; Electrocardiography; Female; Heart Block; Heart Rate; Humans; Male; Middle Aged; Nicotine; Pain	1990
Thallium-201 scintigraphy after intravenous infusion of adenosine compared with exercise thallium testing in the diagnosis of coronary artery disease. Journal of the American College of Cardiology, 1991, Volume: 17, Issue:6 Topics: Adenosine; Adult; Coronary Disease; Electrocardiography; Exercise Test; Female; Heart Conduction System; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Pain; Thallium Radioisotopes; Thorax; Tomography, Emission-Computed, Single-Photon	1991
Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord. Brain research, 1990, Aug-06, Volume: 524, Issue:2 Topics: 5,7-Dihydroxytryptamine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Synergism; Hot Temperature; Hydroxydopamines; Male; Methysergide; Norepinephrine; Oxidopamine; Pain; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Serotonin; Spinal Cord; Theophylline	1990
Antinociception produced by interactions between intrathecally administered adenosine agonists and norepinephrine. Brain research, 1990, Apr-16, Volume: 513, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Male; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Receptors, Purinergic; Spinal Cord	1990
Diagnosis of coronary artery disease by controlled coronary vasodilation with adenosine and thallium-201 scintigraphy in patients unable to exercise. Circulation, 1990, Volume: 82, Issue:1 Topics: Adenosine; Adult; Aged; Aged, 80 and over; Angiography; Coronary Angiography; Coronary Disease; Coronary Vessels; Electrocardiography; Exercise; Female; Hemodynamics; Humans; Jaw; Male; Middle Aged; Pain; Pharynx; Radionuclide Imaging; Thallium Radioisotopes; Thorax; Vasodilation	1990
Antinociceptive interactions between intrathecally administered alpha noradrenergic agonists and 5'-N-ethylcarboxamide adenosine. Brain research, 1990, Jun-11, Volume: 519, Issue:1-2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Injections, Spinal; Male; Norepinephrine; Pain; Phenylephrine; Rats; Rats, Inbred Strains; Spinal Cord; Vasodilator Agents	1990
Behavior induced by putative nociceptive neurotransmitters is inhibited by adenosine or adenosine analogs coadministered intrathecally. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2 Topics: Adenosine; Animals; Aspartic Acid; Behavior, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Spinal; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Pain; Substance P	1988
Assessment of the role of A1/A2 adenosine receptors mediating the purine antinociception, motor and autonomic function in the rat spinal cord. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous System; Blood Pressure; Caffeine; Male; Movement; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Spinal Cord; Urinary Bladder	1989
Classification of adenosine receptors mediating antinociception in the rat spinal cord. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Male; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Spinal Cord; Theophylline	1986
Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 283, Issue:2 Topics: Acetylcholine; Action Potentials; Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Blood Pressure; Drug Synergism; Ear; Eledoisin; Epinephrine; Female; Histamine; In Vitro Techniques; Male; Oxytocin; Pain; Peptides; Potassium Chloride; Prostaglandins; Rabbits; Respiration; Sensory Receptor Cells; Serotonin; Substance P; Time Factors; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins; Venous Pressure	1974