zm 230487 has been researched along with carbostyril in 14 studies
| Studies (zm 230487) | Trials (zm 230487) | Recent Studies (post-2010) (zm 230487) | Studies (carbostyril) | Trials (carbostyril) | Recent Studies (post-2010) (carbostyril) |
|---|---|---|---|---|---|
| 17 | 0 | 0 | 12,855 | 1,323 | 5,611 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buckner, CK; Dea, DM; DeHaas, CJ; Krell, RD; Kusner, EJ; Marks, RL | 1 |
| Nourshargh, S; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Beno, DW; Davis, BH; Mullen, J | 1 |
| Hellewell, PG; Teixeira, MM | 1 |
| Hellewell, PG; Macari, DM; Teixeira, MM | 1 |
| Ammon, HP; Brungs, M; Safayhi, H; Sailer, ER; Schneider, N; Steinhilber, D; Werz, O | 1 |
| Bode, H; Fromm, M; Riecken, EO; Schmitz, H; Scholz, P; Schulzke, JD | 1 |
| Henseler, M; Steinhilber, D; Szellas, D; Werz, O | 1 |
| Al-Rashed, S; Bennett, G; Brain, DS; Hoult, SJR | 1 |
| Giembycz, MA; Hellewell, PG; Lindsay, MA; Teixeira, MM | 1 |
| Anderson, GI; Chen, YF; Gilbert, R; Langman, M; MacQuarrie, R; Osinga, C | 1 |
| Alcaraz, MJ; Guillén, MI; Vicente, AM | 1 |
| Fischer, L; Rådmark, O; Steinhilber, D; Szellas, D; Werz, O | 1 |
| Ji, X; Kurahashi, K; Murakami, S; Nishihashi, T; Trandafir, CC; Wang, A | 1 |
14 other study(ies) available for zm 230487 and carbostyril
| Article | Year |
|---|---|
The 5-lipoxygenase inhibitors ZD2138 and ZM230487 are potent and selective inhibitors of several antigen-induced guinea-pig pulmonary responses.
Topics: Airway Resistance; Animals; Antigens; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine Release; Indoles; Leukotrienes; Lipoxygenase Inhibitors; Lung; Male; Phospholipases A; Phospholipases A2; Pyrans; Quinolones; Thromboxane B2; Thromboxane-A Synthase | 1994 |
Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators.
Topics: Animals; Antibodies, Monoclonal; Biphenyl Compounds; Chlorpheniramine; Dihydropyridines; Dose-Response Relationship, Drug; Edema; Female; Guinea Pigs; Imidazoles; Indoles; Inflammation; Isoindoles; Neurokinin-1 Receptor Antagonists; Pyrans; Quinolones; Skin; Substance P; Time Factors | 1995 |
Lipoxygenase inhibitors block PDGF-induced mitogenesis: a MAPK-independent mechanism that blocks fos and egr.
Topics: Animals; Arachidonate 5-Lipoxygenase; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; DNA; Gene Expression; Genes, fos; Lipoxygenase Inhibitors; Liver; Male; Masoprocol; Platelet-Derived Growth Factor; Pyrans; Quinolones; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Effect of a 5-lipoxygenase inhibitor, ZM 230487, on cutaneous allergic inflammation in the guinea-pig.
Topics: Animals; Arachidonic Acid; Edema; Eosinophils; Guinea Pigs; Leukotriene B4; Lipoxygenase Inhibitors; Male; Passive Cutaneous Anaphylaxis; Pyrans; Quinolones | 1994 |
Priming of eosinophil recruitment in vivo by LPS pretreatment.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Azepines; CD18 Antigens; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Complement C5a, des-Arginine; Cycloheximide; Drug Synergism; Edema; Eosinophilia; Eosinophils; Female; Guinea Pigs; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Neutrophils; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Protein Synthesis Inhibitors; Pyrans; Quinolones; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Sialoglycoproteins; Skin; Triazoles; Zymosan | 1996 |
A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6.
Topics: Arachidonate 5-Lipoxygenase; Benzeneacetamides; Cell Differentiation; Chromatography, High Pressure Liquid; Enzyme Induction; HL-60 Cells; Humans; Hydroxamic Acids; In Vitro Techniques; Indoles; Leukemia, Myeloid; Leukotriene Antagonists; Leukotrienes; Pyrans; Quinolones; Triterpenes; Tumor Cells, Cultured; Up-Regulation | 1997 |
IL-1beta and TNF-alpha, but not IFN-alpha, IFN-gamma, IL-6 or IL-8, are secretory mediators in human distal colon.
Topics: Chlorides; Colon; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enteric Nervous System; Humans; In Vitro Techniques; Indomethacin; Interferon-alpha; Interferon-gamma; Interleukin-1; Interleukin-6; Interleukin-8; Intestinal Mucosa; Ion Transport; Lipoxygenase Inhibitors; Pyrans; Quinolones; Radioimmunoassay; Sodium; Tetrodotoxin; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Nonredox 5-lipoxygenase inhibitors require glutathione peroxidase for efficient inhibition of 5-lipoxygenase activity.
Topics: Arachidonate 5-Lipoxygenase; Bridged Bicyclo Compounds; Cells, Cultured; Enzyme Activation; Escherichia coli; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Lipoxygenase Inhibitors; Oxidation-Reduction; Oxidative Stress; Peroxidase; Pyrans; Quinolines; Quinolones; Selenium; Sulfhydryl Compounds | 1998 |
Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils.
Topics: Animals; Antibodies; Hindlimb; Histamine H1 Antagonists; Hyperalgesia; Leukotrienes; Lipoxygenase Inhibitors; Male; Mast Cells; Methysergide; Nerve Growth Factors; Neutrophils; Nociceptors; Pain Threshold; Peroxidase; Pyrans; Pyrilamine; Quinolones; Rats; Rats, Wistar; Serotonin Agents; Skin | 1998 |
Role of arachidonic acid in leukotriene B(4)-induced guinea-pig eosinophil homotypic aggregation.
Topics: Animals; Arachidonic Acid; Calcium; Cell Aggregation; Dose-Response Relationship, Drug; Eosinophils; Female; Guinea Pigs; Leukotriene Antagonists; Leukotriene B4; Lipoxygenase Inhibitors; Male; Phospholipases A; Pyrans; Quinacrine; Quinolones; Tetradecanoylphorbol Acetate; Tetrazoles | 1999 |
Inhibition of leukotriene function can modulate particulate-induced changes in bone cell differentiation and activity.
Topics: Animals; Bone Resorption; Cell Differentiation; Leukotrienes; Mice; Osteoclasts; Pyrans; Quinolones; Rabbits | 2001 |
Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienes in zymosan-activated macrophages.
Topics: Amidines; Animals; Benzylamines; Cell Line; Chick Embryo; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxyurea; Indomethacin; Isoenzymes; Leukotriene B4; Leukotriene C4; Leukotrienes; Macrophage Activation; Macrophages; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrans; Quinolones; Sulfonamides; Time Factors; Transcription Factor AP-1; Zymosan | 2001 |
Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors.
Topics: Arachidonate 5-Lipoxygenase; Arsenites; Benzeneacetamides; Bridged Bicyclo Compounds; Calcimycin; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Hydroxamic Acids; Lipoxygenase Inhibitors; Mitogen-Activated Protein Kinases; Mutation, Missense; Neutrophils; Peroxides; Phloroglucinol; Phosphorylation; Pyrans; Quinolines; Quinolones; Sodium Chloride; Sodium Compounds; Terpenes | 2003 |
Participation of vasopressin in the development of cerebral vasospasm in a rat model of subarachnoid haemorrhage.
Topics: Animals; Arginine Vasopressin; Basilar Artery; Disease Models, Animal; Female; Indoles; Pyrans; Pyrrolidines; Quinolones; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2004 |