zileuton and mk 0591
zileuton has been researched along with mk 0591 in 8 studies
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Brideau, C; Chan, CC; Dubé, D; Ducharme, Y; Falgueyret, JP; Gillard, JW; Guay, J; Hutchinson, JH; McFarlane, CS; Riendeau, D | 1 |
| Brideau, C; Chan, C; Falgueyret, JP; Guay, J; Hutchinson, JH; Jones, TR; Lépine, C; Macdonald, D; McFarlane, CS; Riendeau, D | 1 |
| Brideau, C; Chan, CC; Chauret, N; Delorme, D; Desmarais, S; Dubé, D; Ducharme, Y; Falgueyret, JP; Fortin, R; Girard, Y; Guay, J; Hamel, P; Jones, TR; Lépine, C; Li, C; McAuliffe, M; McFarlane, CS; Nicoll-Griffith, DA; Riendeau, D; Yergey, JA | 1 |
| Brideau, C; Chan, CC; Delorme, D; Desmarais, S; Dubé, D; Ducharme, Y; Ethier, D; Falgueyret, JP; Girard, Y; Grimm, E; Guay, J; Hamel, P; Jones, TR; Kwong, E; McAuliffe, M; McFarlane, CS; Piechuta, H; Riendeau, D; Roumi, M; Tagari, P; Young, RN | 1 |
| Singh, P | 1 |
| Prasher, P; Singh, P | 1 |
| Bhatti, R; Dhillon, P; Prasher, P; Singh, P | 1 |
| Black, C; Brideau, C; Chan, C; Ford-Hutchinson, A; Frenette, R; Tagari, P | 1 |
Other Studies
8 other study(ies) available for zileuton and mk 0591
| Article | Year |
|---|---|
Naphthalenic lignan lactones as selective, nonredox 5-lipoxygenase inhibitors. Synthesis and biological activity of (methoxyalkyl)thiazole and methoxytetrahydropyran hybrids.
Topics: Animals; Benzofurans; Humans; Lactones; Lipoxygenase; Lipoxygenase Inhibitors; Male; Naphthalenes; Neutrophils; Pyrans; Rats; Rats, Sprague-Dawley; Saimiri; Structure-Activity Relationship; Thiazoles | 1994 |
Thiopyrano[2,3,4-cd]indoles as 5-lipoxygenase inhibitors: synthesis, biological profile, and resolution of 2-[2-[1-(4-chlorobenzyl)-4-methyl-6-[(5-phenylpyridin-2-yl)methoxy]-4,5 -dihydro-1H-thiopyrano[2,3,4-cd]indol-2-yl]ethoxy]butanoic acid.
Topics: Animals; Bronchoconstriction; Calcimycin; Chromatography, High Pressure Liquid; Humans; Indoles; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Molecular Structure; Pyridines; Rats; Rats, Sprague-Dawley; Saimiri; Sheep; Stereoisomerism; Structure-Activity Relationship; Swine | 1994 |
Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Benzofurans; Bronchoconstriction; Drug Stability; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Microsomes, Liver; Molecular Structure; Naphthalenes; Neutrophils; Nitriles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Saimiri; Structure-Activity Relationship | 1996 |
Substituted (pyridylmethoxy)naphthalenes as potent and orally active 5-lipoxygenase inhibitors; synthesis, biological profile, and pharmacokinetics of L-739,010.
Topics: Animals; Ascaris; Biological Availability; Bronchodilator Agents; Dogs; Dyspnea; Humans; Inflammation; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Molecular Conformation; Molecular Structure; Naphthalenes; Nematode Infections; Pyridines; Rats; Recombinant Proteins; Saimiri; Sheep; Spodoptera; Transfection | 1997 |
N-1, C-3 substituted indoles as 5-LOX inhibitors--in vitro enzyme immunoaasay, mass spectral and molecular docking investigations.
Topics: Immunoenzyme Techniques; Indoles; Lipoxygenase Inhibitors; Mass Spectrometry; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2013 |
Lead modification: amino acid appended indoles as highly effective 5-LOX inhibitors.
Topics: Amino Acids; Indoles; Lipoxygenase Inhibitors; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2014 |
Indole based peptidomimetics as anti-inflammatory and anti-hyperalgesic agents: Dual inhibition of 5-LOX and COX-2 enzymes.
Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 2 Inhibitors; Hyperalgesia; Indoles; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Molecular Structure; Peptidomimetics | 2015 |
Assessment of the in vivo biochemical efficacy of orally active leukotriene biosynthesis inhibitors.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Male; Quinolines | 1993 |