ym 022 has been researched along with pentagastrin in 5 studies
| Studies (ym 022) | Trials (ym 022) | Recent Studies (post-2010) (ym 022) | Studies (pentagastrin) | Trials (pentagastrin) | Recent Studies (post-2010) (pentagastrin) |
|---|---|---|---|---|---|
| 65 | 1 | 8 | 3,639 | 207 | 51 |
| Protein | Taxonomy | ym 022 (IC50) | pentagastrin (IC50) |
|---|---|---|---|
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.8875 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akuzawa, S; Ito, H; Kamato, T; Katuyama, Y; Kobayashi, A; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H | 1 |
| Akuzawa, S; Batt, AR; Kendrick, DA; Miyata, K; Nishida, A; Ohta, M; Rooker, DP; Ryder, H; Satoh, M; Semple, G; Szelke, M | 1 |
| Akuzawa, S; Ito, H; Miyake, A; Miyata, K; Nishida, A; Takemoto, Y; Takinami, Y; Yuki, H | 1 |
| Black, JW; Harper, EA; Shankley, NP | 1 |
| Horie, S; Maruyama, T; Ochi, Y; Watanabe, K; Yano, S | 1 |
5 other study(ies) available for ym 022 and pentagastrin
| Article | Year |
|---|---|
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1994 |
(3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist.
Topics: Administration, Oral; Animals; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Brain; Devazepide; Dogs; Gastric Acid; Hormone Antagonists; Molecular Structure; Pancreas; Pentagastrin; Phenylurea Compounds; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship | 1997 |
YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs.
Topics: Animals; Atropine; Benzodiazepines; Benzodiazepinones; Devazepide; Dogs; Dose-Response Relationship, Drug; Eating; Famotidine; Gastric Acid; Histamine; Histamine H2 Antagonists; Hormone Antagonists; Male; Methacholine Chloride; Muscarinic Antagonists; Pentagastrin; Peptones; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Stomach | 1997 |
Characterization of the binding of a novel radioligand to CCKB/gastrin receptors in membranes from rat cerebral cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Bridged-Ring Compounds; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Hormone Antagonists; Indoles; Kinetics; Male; Meglumine; Membranes; Nootropic Agents; Pentagastrin; Phenylurea Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Tritium | 1999 |
Necessity of intracellular cyclic AMP in inducing gastric acid secretion via muscarinic M3 and cholecystokinin2 receptors on parietal cells in isolated mouse stomach.
Topics: Analysis of Variance; Animals; Benzodiazepines; Bethanechol; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Histamine H2 Antagonists; Male; Mice; Parietal Cells, Gastric; Pentagastrin; Receptor, Cholecystokinin B; Receptor, Muscarinic M3 | 2005 |