xiamycin and carvone

xiamycin has been researched along with carvone* in 1 studies

Other Studies

1 other study(ies) available for xiamycin and carvone

ArticleYear
Total Syntheses of Xiamycins A, C, F, H and Oridamycin A and Preliminary Evaluation of their Anti-Fungal Properties.
    Angewandte Chemie (International ed. in English), 2019, 10-21, Volume: 58, Issue:43

    Divergent and enantiospecific total syntheses of the indolosesquiterpenoids xiamycins A, C, F, H and oridamycin A have been accomplished. The syntheses, which commence from (R)-carvone, employ a key photoinduced benzannulation sequence to forge the carbazole moiety characteristic of these natural products. Late-stage diversification from a common intermediate enabled the first syntheses of xiamycins C and F, and an unexpected one-pot oxidative decarboxylation, which may prove general, led to xiamycin H. All synthetic intermediates and the natural products were tested for anti-fungal activity. Xiamycin H emerged as an inhibitor of three agriculturally relevant fungal pathogens.

    Topics: Antifungal Agents; Cyclization; Cyclohexane Monoterpenes; Decarboxylation; Light; Mitosporic Fungi; Oxidation-Reduction; Sesquiterpenes; Stereoisomerism; Ustilago

2019