Page last updated: 2024-09-05

vx-745 and hki 272

vx-745 has been researched along with hki 272 in 3 studies

Compound Research Comparison

Studies
(vx-745)
Trials
(vx-745)
Recent Studies (post-2010)
(vx-745)
Studies
(hki 272)
Trials
(hki 272)
Recent Studies (post-2010) (hki 272)
5813528342248

Protein Interaction Comparison

ProteinTaxonomyvx-745 (IC50)hki 272 (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.0416
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0298
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.8582
Serine/threonine-protein kinase Nek2Homo sapiens (human)0.274

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for vx-745 and hki 272

ArticleYear
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019