uracil and folic acid

uracil has been researched along with folic acid in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (32.84)	18.7374
1990's	6 (8.96)	18.2507
2000's	16 (23.88)	29.6817
2010's	17 (25.37)	24.3611
2020's	6 (8.96)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Clements, GB	1
Arai, K; Awane, Y; Kitamura, M; Miyashita, K	1
Basappa, SC; Murthy, VS; Vishwanath, P	1
Reidy, JA	1
Arakawa, T; Chiba, R; Chida, N; Hayashi, T; Kakizaki, R; Konno, T; Wada, Y	1
Delk, AS; Rabinowitz, JC	1
Brewer, CF; Santi, DV	1
Dewey, VC; Kidder, GW	1
Viñuela, E	1
Schlee, D; Zurnieden, K	1
Tamhane, DV; Vora, MR	1
Deĭneko, NF; Ikhnenko, RI; Shevela, VV; Shustval', NF; Zviagintseva, TD	1
Howard-Peebles, PN; Krumdieck, CL	1
Okabe, H; Takeda, S; Toko, T; Unemi, N; Yuasa, C	1
Ames, BN; Blount, BC	1
Adachi, I; Hashimoto, T; Ishida, F; Kawakami, K; Matsu, T; Omura, K; Watanabe, Y	1
Fida, S; Wickramasinghe, SN	1
Ames, BN; Blount, BC; Brown, ZA; Hard, R; Horne, DW; Koury, MJ; Koury, ST; Pietenpol, JA	1
Duthie, SJ; Grant, G; Narayanan, S	1
Gaté, L; Machover, D; Tapiero, H; Tew, KD	1
Fenech, M; Wang, X	1
PARREIRA, F	2
CARONIA, F; PAGLIARO, L; PICCARDO, MG	1
BISHOP, FS; ROGOSA, M	1
BAKER, H; FRANK, O; LEEVY, CM; TEN-HOVE, W	1
CAVANAGH, D; FERGUSON, JH; MARTIN, DS	1
LAMBE, RF; WILLIAMS, DC	1
ELION, GB; FALCO, EA; HITCHINGS, GH	1
Bagley, PJ; Choi, SW; Friso, S; Ghandour, H; Mason, JB; Selhub, J	1
Ames, BN; Courtemanche, C; Crott, J; Elson-Schwab, I; Fenech, M; Lee, BL; Mashiyama, ST; Ong, CN	1
Abdalla, H; Cabelof, DC; Heydari, AR; Kapoor, D; Nakamura, J; Raffoul, JJ	1
Basten, G; Duthie, SJ; Little, J; McConnell, J; Narayanan, S; Piyathilake, CJ; Powers, H; Sharp, L	1
HAWKINS, V; HORRIGAN, D; JARROLD, T; MUELLER, JF; SEAMAN, A; VILTER, CF; VILTER, RW	1
Catane, R; Elkayam, R; Koller, M; Kundel, Y; Pfeffer, MR; Symon, Z; Zehavi, M; Zmora, O	1
Kalemba, M; Kapiszewska, M; Milewicz, T; Wojciech, U	1
Basten, GP; Duthie, SJ; Hill, MH; Pirie, L; Powers, HJ; Vaughan, N	1
Brochier-Armanet, C; Grosjean, H; Myllykallio, H; Skouloubris, S; Urbonavicius, J	1
Crott, JW; de Boer, SY; Friederich, P; Kampman, E; Keijer, J; Kok, FJ; Mason, JB; Nagengast, FM; Pellis, L; van Bergeijk, JD; van den Donk, M; van Engeland, M	1
Chanson, A; Ciappio, ED; Crott, JW; DeVos, L; Liu, Z; Mason, JB; Parnell, LD; Tucker, KL	1
Allen, RH; Gao, D; Girnary, HH; MacFarlane, AJ; Perry, CA; Shane, B; Stabler, SP; Stover, PJ	1
Austin, RC; Campan, M; Chiang, EP; Cho, RC; Choi, SW; Dickhout, J; Jang, H; Kim, YI; Laird, PW; Lucock, M; Sohn, KJ; Wang, YC; Weisenberger, DJ; Yates, Z	1
Amano, S; Kano, H; Kawasaki, A; Kuboi, Y; Mimatsu, K; Oida, T	1
Baron, JA; Chao, WH; Hazra, A; Hunter, DJ; Selhub, J; Ueland, PM	1
Jacobson, MK; Williams, JD	1
Fenech, M	1
FROMMEYER, WB; SPIES, TD	1
Chanson, A; Choi, SW; Friso, S; Jang, H; Kim, KC; Liu, Z; Sauer, J; Smith, DE; Zimmerly, EM	1
Chanson, A; Freudenheim, JL; Goerlitz, DS; Marian, C; Mason, JB; Nie, J; Shields, PG; Tao, M	1
Chang, CK; Downes, CS; Hoey, L; McGlynn, AP; McKerr, G; McNulty, H; Molloy, AM; O'Reilly, SL; Scott, JM; Strain, JJ; Ward, M; Wasson, GR; Weir, DG	1
Kamijo, A; Nagase, H; Okada, K; Sadahiro, S; Suzuki, T; Tanaka, A; Uchida, J	1
Chen, YM; Chiang, EP; Lin, WL; Lin, YJ; Tang, FY; Wang, YC	1
Au, AY; Bull, CF; Fenech, MF; Hande, MP; Low, GK; Mayrhofer, G; O'Callaghan, NJ; Pickett, HA; Zeegers, D	1
MacFarlane, AJ; McEntee, MF; Stover, PJ	1
Agunloye, OC; Brosnan, JT; Brosnan, ME; Field, MS; Kamynina, E; Lamarre, SG; Liebenthal, RP; Stover, PJ	1
Field, MS; Finkelstein, JL; Martiniova, L; Perry, CA; Stover, PJ	1
Chiang, EP; Ko, HA; Lin, YJ; Tang, FY; Wang, YC; Wu, MT	1
Downes, CS; McGlynn, AP; McKerr, G; McNulty, H; Molloy, AM; O'Reilly, SL; Reynolds, J; Scott, JM; Strain, JJ; Ward, M; Wasson, GR; Weir, DG	1
Alonzo, JR; Field, MS; Stover, PJ; Venkataraman, C	1
Bestwick, CS; Catala, GN; Duthie, SJ; Giovannelli, L; Lendoiro, E; Moyer, MP; Russell, WR; Tortora, K	1
Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T	1
Field, MS; Lachenauer, ER; Stabler, SP; Stover, PJ	1
Béven, L; Blanchard, A; Brégeon, D; Crécy-Lagard, V; Douthwaite, S; Goyenvalle, C; Grosjean, H; Hamdane, D; Rose, S; Sirand-Pugnet, P	1
Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D	1
Blum, JE; Brosnan, JT; Brosnan, ME; Fiddler, JL; Field, MS; Lamarre, SG; Phinney, WN; Stabler, SP; Thalacker-Mercer, AE; Xiu, Y	1
Huang, G; Li, W; Li, Z; Sun, Y; Yan, J; Zhou, D	1

Reviews

6 review(s) available for uracil and folic acid

Article	Year
Selection of biochemically variant, in some cases mutant, mammalian cells in culture. Advances in cancer research, 1975, Volume: 21 Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Base Sequence; Carbohydrates; Cell Fusion; Cell Separation; Cells, Cultured; Cricetinae; Dactinomycin; Deoxycytidine; Drug Resistance; Epitopes; Folic Acid; Genes; Genes, Regulator; Guinea Pigs; Hot Temperature; Humans; Immunoglobulins; Mice; Mutation; Nucleosides; Phenotype; Purines; Puromycin; Rabbits; Rats; Temperature; Thymidine; Time Factors; Uracil; Uridine	1975
[Biochemistry and physiology of the flavinogenesis in microorganisms]. Die Pharmazie, 1970, Volume: 25, Issue:11 Topics: Adenine; Bacteria; Biotransformation; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Enzyme Activation; Enzyme Repression; Flavonoids; Folic Acid; Fungi; Glycosides; Guanine Nucleotides; Lactates; Phosphates; Pteridines; Purines; Pyrimidines; Riboflavin; Ribose; RNA; Saccharomyces; Uracil; Xanthine Oxidase; Xanthines	1970
Prevention of pathologies associated with oxidative stress and dietary intake deficiencies: folate deficiency and requirements. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2001, Volume: 55, Issue:7 Topics: Animals; Diet; DNA; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Lipid Peroxidation; Neoplasms; Nutritional Status; Oxidative Stress; Tetrahydrofolate Dehydrogenase; Uracil	2001
In vitro detection of the enzymatic activity of folate-dependent tRNA (Uracil-54,-C5)-methyltransferase: evolutionary implications. Methods in enzymology, 2007, Volume: 425 Topics: Bacillus subtilis; Evolution, Molecular; Folic Acid; tRNA Methyltransferases; Uracil	2007
Folate, DNA damage and the aging brain. Mechanisms of ageing and development, 2010, Volume: 131, Issue:4 Topics: Aging; Animals; Brain; Cell Nucleus; Cytosine; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Methylation; Neurodegenerative Diseases; Rats; Reactive Oxygen Species; Risk Factors; S-Adenosylmethionine; Uracil	2010
Folate, genomic stability and colon cancer: The use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring. Mutation research. Genetic toxicology and environmental mutagenesis, 2019, Volume: 843 Topics: Biological Monitoring; Cell Line; Colonic Neoplasms; Comet Assay; DNA Breaks; DNA Methylation; DNA Repair; DNA Replication; Folic Acid; Folic Acid Deficiency; Genomic Instability; Genotype; Homocystinuria; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Muscle Spasticity; Psychotic Disorders; Risk; Single-Cell Analysis; Uracil	2019

Trials

5 trial(s) available for uracil and folic acid

Article	Year
A phase I study of oral UFT given concomitantly with standard preoperative radiotherapy for rectal cancer. The Israel Medical Association journal : IMAJ, 2004, Volume: 6, Issue:10 Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colectomy; Combined Modality Therapy; Female; Folic Acid; Humans; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Radiotherapy; Rectal Neoplasms; Tegafur; Treatment Outcome; Ultrasonography; Uracil	2004
Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers. British journal of cancer, 2006, Jun-19, Volume: 94, Issue:12 Topics: Adult; Biomarkers; Dietary Supplements; DNA; DNA Methylation; DNA Repair; Female; Folic Acid; Humans; Lymphocytes; Male; Middle Aged; Sensitivity and Specificity; Uracil; Vitamin B Complex	2006
Folic acid and vitamin B-12 supplementation does not favorably influence uracil incorporation and promoter methylation in rectal mucosa DNA of subjects with previous colorectal adenomas. The Journal of nutrition, 2007, Volume: 137, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; DNA Methylation; Erythrocytes; Female; Folic Acid; Genotype; Homocysteine; Humans; Intestinal Mucosa; Male; Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Promoter Regions, Genetic; Uracil; Vitamin B 12	2007
Reduction in γ-glutamyl hydrolase expression is associated with response to uracil and tegafur/leucovorin chemotherapy in patients with colorectal cancer. Anticancer research, 2013, Volume: 33, Issue:8 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Folic Acid; gamma-Glutamyl Hydrolase; Gene Expression Regulation, Neoplastic; Humans; Leucovorin; Male; Middle Aged; Tegafur; Treatment Outcome; Uracil	2013
Folic Acid Supplementation in Postpolypectomy Patients in a Randomized Controlled Trial Increases Tissue Folate Concentrations and Reduces Aberrant DNA Biomarkers in Colonic Tissues Adjacent to the Former Polyp Site. The Journal of nutrition, 2016, Volume: 146, Issue:5 Topics: Adenomatous Polyps; Aged; Biomarkers; Body Mass Index; Colon; Colonic Neoplasms; Colonoscopy; Comet Assay; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Mucosa; Male; Middle Aged; Obesity; Polyps; Uracil; Vitamin B Complex	2016

Other Studies

56 other study(ies) available for uracil and folic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
[Macrocytic anemia as a possible adverse effect of fluoropyrimidines]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 1 Topics: Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Erythrocyte Indices; Female; Fluorouracil; Folic Acid; Humans; Male; Retrospective Studies; Stomach Neoplasms; Tegafur; Uracil; Vitamin B 12	1990
Mechanism of counteraction of aflatoxin toxicity by thymine and folic acid in Bacillus megaterium. Folia microbiologica, 1986, Volume: 31, Issue:4 Topics: Aflatoxin B1; Aflatoxins; Aminopterin; Aspartic Acid; Bacillus megaterium; DNA, Bacterial; Drug Synergism; Folic Acid; Orotic Acid; Thymine; Uracil; Uridine Monophosphate	1986
Folate- and deoxyuridine-sensitive chromatid breakage may result from DNA repair during G2. Mutation research, 1987, Volume: 192, Issue:3 Topics: Aphidicolin; Chromosome Aberrations; Chromosome Fragility; Cytarabine; Deoxyuridine; Diterpenes; DNA Repair; Folic Acid; Humans; In Vitro Techniques; Interphase; Lymphocytes; Uracil	1987
Uracil-uric refractory anemia with peroxidase negative neutrophils. The Tohoku journal of experimental medicine, 1965, Oct-25, Volume: 87, Issue:1 Topics: Anemia, Hypochromic; Anemia, Macrocytic; Blood Cell Count; Bone Marrow; Child; Chromatography; Chromosomes; Female; Folic Acid; Humans; Leukemia; Neutrophils; Peroxidases; Porphyrins; Staining and Labeling; Succinate Dehydrogenase; Uracil; Uracil Nucleotides; Urine; Vitamin B 12	1965
Partial nucleotide sequence of a prokaryote initiator tRNA that functions in its non-formylated form. Nature, 1974, Nov-08, Volume: 252, Issue:5479 Topics: Autoradiography; Bacterial Proteins; Base Sequence; Electrophoresis; Enterococcus faecalis; Folic Acid; Methionine; Nucleotides; Peptide Chain Initiation, Translational; Polynucleotides; RNA, Transfer; Uracil	1974
Model studies of thymidylate synthetase. Intramolecular catalysis of 5-hydrogen exchange and 5-hydroxymethylation of 1-substituted uracils. Biochemistry, 1973, Jun-19, Volume: 12, Issue:13 Topics: Acetals; Carbon Isotopes; Catalysis; Chromatography, Paper; Chromatography, Thin Layer; Deoxyuridine; Deuterium; Ethers, Cyclic; Folic Acid; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Chemical; Protons; Pyrimidinones; Ribonucleosides; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thymidylate Synthase; Tritium; Uracil; Uridine	1973
The sites of action of allopurinol in Crithidia fasciculata. The Journal of protozoology, 1973, Volume: 20, Issue:5 Topics: Adenine; Allopurinol; Animals; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cytosine; Dose-Response Relationship, Drug; Eukaryota; Folic Acid; Guanine; Hypoxanthines; Orotic Acid; Pentosyltransferases; Pterins; Spectrophotometry; Uracil; Xanthines	1973
Virus-specific proteins in Escherichia coli infected with the RNA bacteriophage MS2. Bulletin de la Societe de chimie biologique, 1968, Volume: 50, Issue:12 Topics: Bacterial Proteins; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Dactinomycin; Detergents; Electrophoresis; Escherichia coli; Eukaryota; Folic Acid; Genetic Code; Histidine; Kinetics; Leucine; Methionine; Molecular Weight; Peptides; Protoplasts; RNA, Viral; Tritium; Uracil; Viral Proteins; Virus Replication	1968
Metabolic studies with Neurospora: action of 5-Bromo- and 5-nitrouracils. Archiv fur Mikrobiologie, 1966, Sep-08, Volume: 54, Issue:3 Topics: Chromatography, Paper; DNA; Folic Acid; Leucovorin; Neurospora; RNA; Uracil	1966
[Therapeutic action of nucleic acid-synthesis stimulants in peptic ulcer]. Vrachebnoe delo, 1980, Issue:10 Topics: Adult; DNA; Drug Evaluation; Folic Acid; Humans; Middle Aged; Pentoxyl; Peptic Ulcer; RNA; Stimulation, Chemical; Uracil; Vitamin B 12	1980
On the nature of folic-acid-sensitive fragile sites in human chromosomes: an hypothesis. American journal of medical genetics, 1983, Volume: 16, Issue:1 Topics: Base Composition; Chromatin; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human; DNA; Folic Acid; Humans; Methylation; Models, Biological; Nucleoproteins; Thymine; Uracil	1983
[Augmentation of chemotherapeutic efficaciousness of UFT by oral l-leucovorin--l-leucovorin factors enhancing cytotoxic activity of 5-fluorouracil]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:13 Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fluorouracil; Folic Acid; Humans; Leucovorin; Tegafur; Tumor Cells, Cultured; Uracil	1995
Development of a sensitive assay for detection of uracil in DNA. Advances in experimental medicine and biology, 1993, Volume: 338 Topics: Animals; DNA; Folic Acid; Folic Acid Deficiency; Indicators and Reagents; Liver; Mass Spectrometry; Methotrexate; Microchemistry; Rats; Rats, Inbred F344; Uracil	1993
[Changes of the number of FdUMP binding sites of thymidylate synthase and folate pools in human colorectal carcinomas following the administration of tegafur and uracil: preliminary report]. Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Colorectal Neoplasms; Fluorodeoxyuridylate; Folic Acid; Humans; Tegafur; Thymidylate Synthase; Uracil	1993
Misincorporation of uracil into the DNA of folate- and B12-deficient HL60 cells. European journal of haematology, 1993, Volume: 50, Issue:3 Topics: Chromatography, Ion Exchange; DNA, Neoplasm; Folic Acid; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Tritium; Tumor Cells, Cultured; Uracil; Vitamin B 12	1993
Apoptosis of late-stage erythroblasts in megaloblastic anemia: association with DNA damage and macrocyte production. Blood, 1997, Jun-15, Volume: 89, Issue:12 Topics: Anemia, Megaloblastic; Animals; Apoptosis; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA Replication; Erythroblasts; Erythrocytes, Abnormal; Erythropoiesis; Female; Folic Acid; Folic Acid Deficiency; Humans; Mice; Thymidine; Thymidylate Synthase; Tumor Suppressor Protein p53; Uracil	1997
Increased uracil misincorporation in lymphocytes from folate-deficient rats. British journal of cancer, 2000, Volume: 83, Issue:11 Topics: Animals; Choline Deficiency; Comet Assay; DNA; DNA Damage; Erythrocytes; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; Rats; Uracil; Vitamin B 12	2000
A comparison of folic acid and 5-methyltetrahydrofolate for prevention of DNA damage and cell death in human lymphocytes in vitro. Mutagenesis, 2003, Volume: 18, Issue:1 Topics: Adult; Biological Availability; Carrier Proteins; Cell Division; Cells, Cultured; Choline; Chromosome Breakage; Chromosomes, Human; Deoxyuracil Nucleotides; DNA; DNA Damage; DNA Methylation; DNA Replication; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lymphocyte Activation; Lymphocytes; Membrane Transport Proteins; Methionine; Micronucleus Tests; Middle Aged; Oxidation-Reduction; Phytohemagglutinins; Prodrugs; Receptors, Cell Surface; Reduced Folate Carrier Protein; Tetrahydrofolates; Uracil	2003
[In vitro effect of vitamin B 12, folic acid and uracil on bone marrow in two cases of megaloblastic anemia; preliminary note]. Jornal do medico, 1953, Sep-05, Volume: 22, Issue:554 Topics: Anemia; Anemia, Megaloblastic; Bone Marrow; Folic Acid; Humans; In Vitro Techniques; Uracil; Vitamin B 12; Vitamin B Complex	1953
[In vitro effect of vitamin B12, folic acid and uracil on bone marrow in two cases of megaloblastic anemia]. Gazeta medica portuguesa, 1953, Volume: 6, Issue:3 Topics: Anemia; Anemia, Megaloblastic; Bone Marrow; Folic Acid; Humans; In Vitro Techniques; Uracil; Vitamin B 12; Vitamin B Complex	1953
[Correlation of biochemical data, clinical aspects and therapeutic reaction in megaloblastosis]. La Riforma medica, 1956, Oct-06, Volume: 70, Issue:40 Topics: Anemia; beta-Thalassemia; Corrinoids; Erythroblasts; Folic Acid; Hematinics; Humans; Uracil; Vitamin B 12	1956
THE GENUS VEILLONELLA . II. NUTRITIONAL STUDIES. Journal of bacteriology, 1964, Volume: 87 Topics: 4-Aminobenzoic Acid; Animals; Biotin; Cadaverine; Calcium; Culture Media; Folic Acid; Hypoxanthines; Niacin; Nicotinic Acids; Pantothenic Acid; Putrescine; Pyridoxine; Rats; Research; Riboflavin; Thiamine; United States; Uracil; Veillonella	1964
FOLIC ACID DEFICIENCY AND HEPATIC DNA SYNTHESIS. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 117 Topics: Avitaminosis; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; Folic Acid; Folic Acid Deficiency; Hepatitis; Liver Diseases; Liver Regeneration; Metabolism; Necrosis; Pharmacology; Rats; Research; Thymidine; Uracil; Vitamin B 12	1964
CLOSED PELVIC PERFUSION IN ADVANCED GYNECOLOGIC CANCER. Southern medical journal, 1965, Volume: 58 Topics: Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Folic Acid; Genital Neoplasms, Female; Geriatrics; Humans; Lymphography; Neoplasms; Nitrogen Mustard Compounds; Palliative Care; Pelvis; Postoperative Care; Prognosis; Toxicology; Uracil; Uracil Mustard; Urography; Uterine Cervical Neoplasms; Vulvar Neoplasms	1965
THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS. The Biochemical journal, 1965, Volume: 95 Topics: Aminopterin; Antimetabolites; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Folic Acid; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Mercaptopurine; Methotrexate; NAD; Oxidoreductases; Research; Steroids; Testosterone; Uracil	1965
Antagonists of nucleic acid derivatives. II. Reversal studies with substances structurally related to thymine. The Journal of biological chemistry, 1950, Volume: 185, Issue:2 Topics: Folic Acid; Lacticaseibacillus casei; Nucleic Acids; Thymine; Uracil	1950
Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium. The Journal of nutrition, 2004, Volume: 134, Issue:4 Topics: Animals; Body Weight; Colon; Colorectal Neoplasms; DNA; DNA Methylation; Epithelium; Folic Acid; Gas Chromatography-Mass Spectrometry; Intestinal Mucosa; Male; Rats; Rats, Sprague-Dawley; Uracil; Vitamin B 12; Vitamin B 12 Deficiency	2004
Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes. Analytical biochemistry, 2004, Jul-01, Volume: 330, Issue:1 Topics: Cells, Cultured; DNA; DNA Damage; Folic Acid; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Humans; Lymphocytes; Nucleosides; Sensitivity and Specificity; Uracil	2004
Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency. The Journal of biological chemistry, 2004, Aug-27, Volume: 279, Issue:35 Topics: Animal Feed; Animals; Blotting, Western; Cell Nucleus; Dietary Supplements; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; Folic Acid; Folic Acid Deficiency; Heterozygote; Liver; Male; Mice; Mice, Inbred C57BL; Models, Chemical; Oxygen; Tumor Suppressor Protein p53; Up-Regulation; Uracil; Uracil-DNA Glycosidase	2004
Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colorectal Neoplasms; DNA Damage; DNA Methylation; Erythrocytes; Female; Folic Acid; Genetic Carrier Screening; Genetic Variation; Genotype; Homocysteine; Homozygote; Humans; Isoenzymes; Lymphocytes; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Genetic; Risk; Scotland; Tetrahydrofolates; Uracil; Vitamin B 12	2004
Studies on the relationships of vitamin B12, folic acid, thymine, uracil and methyl group donors in persons with pernicious anemia and related megaloblastic anemias. Blood, 1950, Volume: 5, Issue:8 Topics: Anemia; Anemia, Megaloblastic; Anemia, Pernicious; Folic Acid; Hematinics; Thymine; Tissue Donors; Uracil; Vitamin B 12	1950
Uracil misincorporation into DNA of leukocytes of young women with positive folate balance depends on plasma vitamin B12 concentrations and methylenetetrahydrofolate reductase polymorphisms. A pilot study. The Journal of nutritional biochemistry, 2005, Volume: 16, Issue:8 Topics: Adult; DNA; DNA Damage; DNA Glycosylases; Female; Folic Acid; Genotype; Humans; Leukocytes; Methylenetetrahydrofolate Reductase (NADPH2); Pilot Projects; Polymorphism, Genetic; Uracil; Uracil-DNA Glycosidase; Vitamin B 12	2005
Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. The American journal of clinical nutrition, 2008, Volume: 88, Issue:4 Topics: Aged; Chromosome Aberrations; Cohort Studies; DNA Damage; DNA Methylation; Female; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Male; Membrane Transport Proteins; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Uracil	2008
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. The Journal of biological chemistry, 2009, Jan-16, Volume: 284, Issue:3 Topics: Animals; Animals, Genetically Modified; Biomarkers; DNA; Folic Acid; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Homocysteine; Methylation; Mice; Thymidine Monophosphate; Uracil	2009
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification. International journal of cancer, 2009, May-01, Volume: 124, Issue:9 Topics: Blotting, Western; Breast Neoplasms; Colonic Neoplasms; CpG Islands; DNA Damage; DNA Methylation; Folic Acid; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Humans; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Polymorphism, Genetic; Risk Factors; Tumor Cells, Cultured; Uracil	2009
[Drug-induced liver injury associated with uracil/tegafur + folinate therapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:11 Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Female; Folic Acid; Humans; Tegafur; Uracil	2009
Uracil misincorporation into DNA and folic acid supplementation. The American journal of clinical nutrition, 2010, Volume: 91, Issue:1 Topics: Adenoma; Aged; Alcohol Drinking; Aspirin; Colonoscopy; Colorectal Neoplasms; Dietary Supplements; DNA; Female; Folic Acid; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Recurrence, Local; Placebos; Randomized Controlled Trials as Topic; Risk Factors; Uracil	2010
Photobiological implications of folate depletion and repletion in cultured human keratinocytes. Journal of photochemistry and photobiology. B, Biology, 2010, Apr-02, Volume: 99, Issue:1 Topics: Cell Line; Comet Assay; DNA Damage; Folic Acid; Folic Acid Deficiency; Genomic Instability; Humans; Keratinocytes; S Phase; Tetrahydrofolates; Ultraviolet Rays; Uracil	2010
Relative clinical and hematologic effects of concentrated liver extract, synthetic folic acid and synthetic 5-methyl uracil in the treatment of macrocytic anemias in relapse. The American journal of the medical sciences, 1947, Volume: 213, Issue:2 Topics: Anemia; Anemia, Macrocytic; Folic Acid; Liver; Liver Extracts; Recurrence; Uracil; Vitamin B Complex; Vitamins	1947
Folate supplementation differently affects uracil content in DNA in the mouse colon and liver. The British journal of nutrition, 2011, Volume: 105, Issue:5 Topics: Age Factors; Animals; Colon; Dietary Supplements; DNA; Folic Acid; Gas Chromatography-Mass Spectrometry; Lacticaseibacillus casei; Liver; Male; Mice; Mice, Inbred C57BL; Mutation; Thymidine; Thymidine Monophosphate; Uracil; Vitamin B Complex	2011
Single nucleotide polymorphisms in uracil-processing genes, intake of one-carbon nutrients and breast cancer risk. European journal of clinical nutrition, 2011, Volume: 65, Issue:6 Topics: Adult; Aged; Breast Neoplasms; Carbon; Case-Control Studies; DNA; Female; Folic Acid; Genotype; Heterozygote; Humans; Middle Aged; Mutation; Odds Ratio; Polymorphism, Single Nucleotide; Postmenopause; Risk Factors; Uracil; Uracil-DNA Glycosidase	2011
Low colonocyte folate is associated with uracil misincorporation and global DNA hypomethylation in human colorectum. The Journal of nutrition, 2013, Volume: 143, Issue:1 Topics: Adenomatous Polyps; Adult; Aged; Base Pair Mismatch; Biomarkers; Case-Control Studies; Colon; Colonic Polyps; DNA; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Humans; Hyperplasia; Intestinal Mucosa; Male; Middle Aged; Organ Specificity; Rectum; Uracil	2013
A novel role of the tumor suppressor GNMT in cellular defense against DNA damage. International journal of cancer, 2014, Feb-15, Volume: 134, Issue:4 Topics: Adenosine; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Dietary Supplements; DNA Damage; DNA Methylation; Female; Fluorescent Antibody Technique, Indirect; Folic Acid; Glycine N-Methyltransferase; Hepatocytes; Homocysteine; Humans; Liver; Liver Neoplasms; Male; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Knockout; Minor Histocompatibility Antigens; Protein Transport; Purines; Pyrimidines; S-Adenosylhomocysteine; S-Adenosylmethionine; Tetrahydrofolates; Uracil	2014
Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells. Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:1 Topics: Azacitidine; Biomarkers; Chromosomal Instability; Cytokinesis; Decitabine; Diet; DNA Damage; DNA Methylation; Folic Acid; Folic Acid Deficiency; Humans; Telomerase; Telomere; Uracil	2014
Azoxymethane-induced colon carcinogenesis in mice occurs independently of de novo thymidylate synthesis capacity. The Journal of nutrition, 2014, Volume: 144, Issue:4 Topics: Animals; Azoxymethane; Carcinogenesis; Choline Deficiency; Colon; Colonic Neoplasms; Crosses, Genetic; Disease Models, Animal; DNA; Extracellular Matrix Proteins; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Proteins; Protein-Lysine 6-Oxidase; Random Allocation; Thymidine Monophosphate; Tumor Burden; Uracil	2014
Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency. The Journal of biological chemistry, 2014, Oct-24, Volume: 289, Issue:43 Topics: Animals; Cell Cycle Checkpoints; Cell Line; Cell Nucleus; Coenzymes; Diet; DNA; Female; Folic Acid; Folic Acid Deficiency; Formates; Gene Knockdown Techniques; Glycine Hydroxymethyltransferase; Humans; Liver; Male; Methionine; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Inbred C57BL; Protein Transport; Purines; S Phase; Thymidine Monophosphate; Uracil	2014
Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects. The American journal of clinical nutrition, 2015, Volume: 101, Issue:4 Topics: Animals; Deoxyuridine; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; HeLa Cells; Humans; Maternal Nutritional Physiological Phenomena; Mice; Neural Tube; Neural Tube Defects; Pregnancy; Thymidine; Uracil; Uridine	2015
Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR). Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl Topics: Animals; Carbon; DNA Damage; DNA Methylation; Folic Acid; Genotype; Glycine N-Methyltransferase; Hep G2 Cells; Homocysteine; Humans; Liver; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Neoplasms; Nucleotides; Nutritional Status; Purines; S-Adenosylmethionine; Uracil	2015
The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA. The Journal of biological chemistry, 2018, 12-28, Volume: 293, Issue:52 Topics: Biological Transport, Active; DNA, Mitochondrial; Folic Acid; Gene Expression Regulation; HeLa Cells; Humans; Membrane Proteins; Mitochondrial Diseases; Mitochondrial Proteins; Thymidine Monophosphate; Uracil	2018
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio. Nucleic acids research, 2020, 01-10, Volume: 48, Issue:1 Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil	2020
p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice. The Journal of nutrition, 2020, 07-01, Volume: 150, Issue:7 Topics: Animals; DNA; Embryo, Mammalian; Folic Acid; Gene Expression Regulation, Developmental; Mice; Mice, Knockout; Neural Tube Defects; Tumor Suppressor Protein p53; Uracil; Vitamin B Complex	2020
Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes. Biomolecules, 2020, 04-10, Volume: 10, Issue:4 Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Conserved Sequence; Dinitrocresols; Evolution, Molecular; Folic Acid; Methylation; Methyltransferases; Models, Molecular; Nucleic Acids; RNA, Ribosomal, 23S; RNA, Transfer; Tenericutes; Uracil	2020
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism. The Journal of nutritional biochemistry, 2021, Volume: 97 Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil	2021
Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA. The Journal of nutrition, 2021, 10-01, Volume: 151, Issue:10 Topics: Animals; DNA, Mitochondrial; Fibroblasts; Folic Acid; Folic Acid Deficiency; Mice; Mitochondria; Respiration; Uracil	2021
Early Life Stage Folic Acid Deficiency Delays the Neurobehavioral Development and Cognitive Function of Rat Offspring by Hindering De Novo Telomere Synthesis. International journal of molecular sciences, 2022, Jun-22, Volume: 23, Issue:13 Topics: Animals; Cognition; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Rats; Telomere; Uracil	2022

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