uracil and allopurinol

uracil has been researched along with allopurinol in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199012 (41.38)18.7374
1990's6 (20.69)18.2507
2000's9 (31.03)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
de Bree, PK; Grift, J; Stoop, JW; van Gennip, AH; Wadman, SK; Zegers, BJ1
Kalow, W; Tang, BK1
Anada, E; Fujimura, T; Fujita, H; Haryo, S; Sawasaki, K; Shima, Y; Shiota, S1
Bronk, JR; Shaw, MI1
Cox, GB; Gibson, F1
Dewey, VC; Kidder, GW1
Schlee, D; Zurnieden, K1
Brown, GB; Lee, TC; Myles, A; Stöhrer, G; Teller, MN1
Bonk, U; Coutelle, C; Coutelle, R; Felicetti, D; Rath, FW; Traub, F1
Berlin, RD1
Simmonds, HA1
Thiry, L1
Kersley, GD1
Hashimoto, M; Matsunaga, Y; Miyazaki, H; Sunahara, N; Yokogawa, K1
Porter, DJ1
Almond, MR; Harrington, JA; Lowen, GT; Porter, DJ; Spector, T; Zimmerman, TP1
Fraisse, L; Rabion, A; Roche, B; Seris, JL; Verlhac, JB1
Fujimura, Y; Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsui, T; Tsutsumi, Z; Yamamoto, T1
Ikeda, K; Kawaguchi, Y; Masuda, H; Matsushima, E; Nagayama, S; Yoshisue, K1
Bechtel, PR; Bechtel, YC; Brientini, MP; Hrusovsky, S; Lelouët, H; Mantion, G; Miguet, JP; Paintaud, G1
Biollaz, J; Décosterd, LA; Kesselring, UW; Nyéki, A1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT1
Barshop, BA; Climent, C; Nyhan, WL; Rubio, V1
Gasic, JM; Isakovic, AJ; Markovic, ID; Rakic, LM; Rakic, MLj; Redzic, ZB; Segal, MB; Thomas, SA1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N1

Reviews

2 review(s) available for uracil and allopurinol

ArticleYear
The use of mutants of Escherichia coli K12 in studying electron transport and oxidative phosphorylation.
    Essays in biochemistry, 1973, Volume: 9

    Topics: Adenosine Triphosphatases; Aerobiosis; Anaerobiosis; Biological Transport, Active; Cell Division; Chromatography, Gel; Electron Transport; Escherichia coli; Fumarates; Glucose; Microscopy, Electron; Mitochondria; Models, Biological; Mutation; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Quinones; Ubiquinone; Uracil; Vitamin K; Xanthine Oxidase

1973
[Biochemistry and physiology of the flavinogenesis in microorganisms].
    Die Pharmazie, 1970, Volume: 25, Issue:11

    Topics: Adenine; Bacteria; Biotransformation; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Enzyme Activation; Enzyme Repression; Flavonoids; Folic Acid; Fungi; Glycosides; Guanine Nucleotides; Lactates; Phosphates; Pteridines; Purines; Pyrimidines; Riboflavin; Ribose; RNA; Saccharomyces; Uracil; Xanthine Oxidase; Xanthines

1970

Other Studies

27 other study(ies) available for uracil and allopurinol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleoside phosphorylase deficiency.
    Clinica chimica acta; international journal of clinical chemistry, 1979, May-02, Volume: 93, Issue:3

    Topics: Allopurinol; Child; Child, Preschool; Chromatography, High Pressure Liquid; Deoxycytidine; Humans; Infant; Ornithine Carbamoyltransferase Deficiency Disease; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; Respiratory Tract Infections; Uracil; Uridine

1979
Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:5 Pt 1

    Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Female; Humans; Longitudinal Studies; Male; Uracil; Xanthine Oxidase

1991
[Prophylactic effect of allopurinol mouthwash against stomatitis induced by the chemotherapy (PMUE regimen) for gastrointestinal malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:14

    Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Gastrointestinal Neoplasms; Humans; Male; Mitomycin; Mouthwashes; Stomatitis; Tegafur; Uracil

1991
The transport of uric acid across mouse small intestine in vitro.
    The Journal of physiology, 1986, Volume: 378

    Topics: Allopurinol; Animals; Biological Transport; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Mice; Mice, Inbred BALB C; Oxypurinol; Serous Membrane; Uracil; Uric Acid

1986
The sites of action of allopurinol in Crithidia fasciculata.
    The Journal of protozoology, 1973, Volume: 20, Issue:5

    Topics: Adenine; Allopurinol; Animals; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cytosine; Dose-Response Relationship, Drug; Eukaryota; Folic Acid; Guanine; Hypoxanthines; Orotic Acid; Pentosyltransferases; Pterins; Spectrophotometry; Uracil; Xanthines

1973
Synthesis and oncogenicity of 3-hydroxyuric acid.
    Biochemistry, 1971, Nov-23, Volume: 10, Issue:24

    Topics: Animals; Benzyl Compounds; Carbon Isotopes; Carcinogens; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Hypoxanthines; Milk; Neoplasms; Nitroso Compounds; Oxidation-Reduction; Rats; Rats, Inbred Strains; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

1971
[Comparative histological and electron microscopic, histochemical and biochemical studies on invasive tumor growth. IV. Behavior of certain transferases oxidoreductases and hydrolases].
    Acta biologica et medica Germanica, 1970, Volume: 24, Issue:1

    Topics: Acid Phosphatase; Animals; Brain; Brain Chemistry; Brain Neoplasms; Carcinoma, Ehrlich Tumor; Glucuronidase; Histocytochemistry; Hyaluronoglucosaminidase; L-Lactate Dehydrogenase; Mice; Microscopy, Electron; Neoplasm Transplantation; Nucleosides; Oxidoreductases; Phosphotransferases; Thymidine; Transferases; Uracil; Uridine; Xanthine Oxidase

1970
Purines: active transport by isolated choroid plexus.
    Science (New York, N.Y.), 1969, Mar-14, Volume: 163, Issue:3872

    Topics: Adenine; Allopurinol; Animals; Biological Transport, Active; Blood-Brain Barrier; Choroid Plexus; Female; Guanine; Hypoxanthines; In Vitro Techniques; Kinetics; Purines; Rabbits; Uracil; Uric Acid; Xanthines

1969
The excretion of urinary pseudouridine in patients treated with allopurinol and oxipurinol.
    The Biochemical journal, 1969, Volume: 111, Issue:3

    Topics: Allopurinol; Amino Acids; Chromatography, Ion Exchange; Chromatography, Thin Layer; Electrophoresis; Humans; Hydrogen-Ion Concentration; Nucleosides; Pyrimidines; Uracil

1969
Viruses grown in the presence of base analogs: specific alteration of susceptibility to inactivation by radiations, mutagens, and protodyes.
    Virology, 1966, Volume: 28, Issue:4

    Topics: Arboviruses; Coloring Agents; Fluorouracil; Guanine; Hydroxylamines; In Vitro Techniques; Light; Methylene Blue; Newcastle disease virus; Nitrites; Nucleic Acids; Nucleosides; Photosensitivity Disorders; Purines; Sulfates; Thiouracil; Ultraviolet Rays; Uracil; Uridine; Virus Cultivation; Xanthine Oxidase

1966
Treatment of gout by reduction of uric acid production.
    Annals of the rheumatic diseases, 1966, Volume: 25, Issue:4

    Topics: Catalase; Drug Synergism; Enzyme Therapy; Gout; Humans; Kidney Calculi; Sulfinpyrazone; Uracil; Uric Acid; Uricosuric Agents; Xanthine Oxidase

1966
A simple method to determine inhibitory activity of xanthine oxidase in vivo.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:2

    Topics: Adenine; Allopurinol; Animals; Kidney; Male; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Uracil; Xanthine Oxidase

1982
Reaction of 5-ethynyluracil with rat liver xanthine oxidase.
    The Journal of biological chemistry, 1994, Nov-11, Volume: 269, Issue:45

    Topics: Allopurinol; Animals; Binding, Competitive; Carbon Radioisotopes; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyanides; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Theoretical; Protein Binding; Rats; Spectrophotometry, Ultraviolet; Uracil; Xanthine Oxidase

1994
5-ethynyl-2(1H)-pyrimidinone: aldehyde oxidase-activation to 5-ethynyluracil, a mechanism-based inactivator of dihydropyrimidine dehydrogenase.
    Biochemical pharmacology, 1994, Mar-29, Volume: 47, Issue:7

    Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Biotransformation; Dihydrouracil Dehydrogenase (NADP); Intestines; Liver; Lung; Oxidation-Reduction; Oxidoreductases; Prodrugs; Pyrimidinones; Rabbits; Rats; Uracil; Xanthine Oxidase

1994
Inhibition of the iron-catalysed formation of hydroxyl radicals by nitrosouracil derivatives: protection of mitochondrial membranes against lipid peroxidation.
    Free radical research communications, 1993, Volume: 19, Issue:6

    Topics: Animals; Catalase; Cattle; Deoxyribose; Hydrogen Peroxide; Hydroxyl Radical; Intracellular Membranes; Iron; Lipid Peroxidation; Mitochondria, Heart; Nitroso Compounds; Oxygen; Thiobarbituric Acid Reactive Substances; Uracil; Xanthine; Xanthine Oxidase; Xanthines

1993
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
    Pharmacology, 2000, Volume: 60, Issue:1

    Topics: Allopurinol; Biological Transport; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Febuxostat; Humans; Hypoxanthine; Inosine; Lung Neoplasms; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Pentosyltransferases; Purines; Pyrimidine Phosphorylases; Thiazoles; Tumor Cells, Cultured; Uracil; Uridine; Xanthine; Xanthine Oxidase

2000
Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10

    Topics: Administration, Oral; Allopurinol; Animals; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Carbon Radioisotopes; Chlorpromazine; Drug Combinations; Drugs, Chinese Herbal; Fluorouracil; Glycyrrhiza; Intestine, Small; Male; Microsomes, Liver; Oxonic Acid; Paeonia; Pyridines; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Tegafur; Tissue Distribution; Triazines; Uracil; Xanthine Oxidase

2000
Caffeine metabolism before and after liver transplantation.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:2

    Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Azathioprine; Caffeine; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Uracil; Xanthine Oxidase

2001
Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, May-05, Volume: 755, Issue:1-2

    Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Models, Chemical; Reproducibility of Results; Uracil; Xanthine Oxidase

2001
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

1997
Pitfalls in the detection of heterozygosity by allopurinol in a variant form of ornithine carbamoyltransferase deficiency.
    Journal of inherited metabolic disease, 2001, Volume: 24, Issue:4

    Topics: Allopurinol; Child; False Negative Reactions; Female; Genetic Carrier Screening; Humans; Mutation; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Uracil

2001
The kinetics of hypoxanthine transport across the perfused choroid plexus of the sheep.
    Brain research, 2002, Jan-25, Volume: 925, Issue:2

    Topics: Adenine; Allopurinol; Animals; Binding, Competitive; Biological Transport; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Hypoxanthine; In Vitro Techniques; Mannitol; Perfusion; Sheep; Sodium; Thioinosine; Thymine; Tritium; Uracil; Xanthine Oxidase

2002
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:4

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2009
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:10

    Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2012
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