Page last updated: 2024-09-04

tipifarnib and tae226

tipifarnib has been researched along with tae226 in 3 studies

Compound Research Comparison

Studies
(tipifarnib)
Trials
(tipifarnib)
Recent Studies (post-2010)
(tipifarnib)
Studies
(tae226)
Trials
(tae226)
Recent Studies (post-2010) (tae226)
309929465049

Protein Interaction Comparison

ProteinTaxonomytipifarnib (IC50)tae226 (IC50)
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Aurora kinase AHomo sapiens (human)0.004
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.86
Epidermal growth factor receptorHomo sapiens (human)0.55
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.71
Insulin receptorHomo sapiens (human)0.036
Insulin-like growth factor 1 receptorHomo sapiens (human)0.1205
Platelet-derived growth factor receptor betaHomo sapiens (human)2.6
Fibroblast growth factor receptor 1Homo sapiens (human)0.75
Focal adhesion kinase 1Homo sapiens (human)0.3135
ALK tyrosine kinase receptorHomo sapiens (human)0.0275

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for tipifarnib and tae226

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020