stilbenes and furan
stilbenes has been researched along with furan* in 2 studies
Other Studies
2 other study(ies) available for stilbenes and furan
| Article | Year |
|---|---|
Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents.
We have synthesized rigid analogues of combretastatin bearing a furan ring in place of the olefinic bridge. These compounds are cytotoxic at nanomolar concentrations in neuroblastoma cells, display a similar structure-activity relationship compared to combretastatin A4, and inhibit tubulin polymerization. We also show that the furan ring can be further functionalized. Thus, it is possible that combretafurans could act as scaffolds for the development of dual-action antitumoral agents. Topics: Anisoles; Antineoplastic Agents; Bibenzyls; Cell Death; Cell Line, Tumor; Drug Screening Assays, Antitumor; Furans; Humans; Molecular Structure; Neuroblastoma; Stilbenes; Structure-Activity Relationship; Tubulin | 2006 |
[The biological properties of ketones in the series of the thiophene isosteres of stilbene and of triphenylethylene].
Topics: Furans; Ketones; Stilbenes; Thiophenes | 1954 |