spermine and sulindac

spermine has been researched along with sulindac in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hughes, A; Smith, NI; Wallace, HM	1
Besselsen, DG; Blohm-Mangone, KA; Gerner, EW; Guillen-R, JM; Ignatenko, NA; Padilla-Torres, JL; Roy, UK; Stringer, DE	1
Chen, WP; Gerner, EW; LaFleur, BJ; McLaren, CE; Meyskens, FL; Thompson, PA; Wertheim, BC; Zell, JA	1

Trials

1 trial(s) available for spermine and sulindac

Article	Year
Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma. Gastroenterology, 2010, Volume: 139, Issue:3 Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome	2010

Article

Year

Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.

Gastroenterology, 2010, Volume: 139, Issue:3

Topics: Adenoma; Aged; Anticarcinogenic Agents; Biomarkers, Pharmacological; Biopsy; Colonoscopy; Colorectal Neoplasms; Dinoprostone; Double-Blind Method; Drug Therapy, Combination; Eflornithine; Enzyme Inhibitors; Female; Humans; Intestinal Mucosa; Likelihood Functions; Logistic Models; Male; Middle Aged; Neoplasms, Second Primary; Polyamines; Putrescine; Rectum; Spermidine; Spermine; Sulindac; Time Factors; Treatment Outcome

2010

Other Studies

2 other study(ies) available for spermine and sulindac

Article	Year
Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells. The Biochemical journal, 2003, Sep-01, Volume: 374, Issue:Pt 2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cell Membrane; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Indoles; Intercalating Agents; Naproxen; Polyamines; Putrescine; Salicylates; Spermidine; Spermine; Sulindac; Tumor Cells, Cultured	2003
Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis. Nutrition and cancer, 2006, Volume: 56, Issue:2 Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Random Allocation; RNA, Messenger; Spermidine; Spermine; Sulindac	2006

Article

Year

Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells.

The Biochemical journal, 2003, Sep-01, Volume: 374, Issue:Pt 2

Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Cell Membrane; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Indoles; Intercalating Agents; Naproxen; Polyamines; Putrescine; Salicylates; Spermidine; Spermine; Sulindac; Tumor Cells, Cultured

2003

Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.

Nutrition and cancer, 2006, Volume: 56, Issue:2

Topics: Adenomatous Polyposis Coli; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Random Allocation; RNA, Messenger; Spermidine; Spermine; Sulindac

2006