spermine and acrolein

spermine has been researched along with acrolein in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19906 (19.35)18.7374
1990's5 (16.13)18.2507
2000's6 (19.35)29.6817
2010's9 (29.03)24.3611
2020's5 (16.13)2.80

Authors

AuthorsStudies
Dewey, DL; Gaugas, JM1
Conant, J; Ishaque, A; Jones, K; Kimsto, L; Lau, C; Wang, E; Wong, B1
Allen, JC; Hussain, JI; Smith, CJ2
Ferrante, A1
Chaproniere-Rickenberg, D; Webber, MM1
Bock, K; Houen, G; Jensen, AL1
Agostinelli, E; Averill-Bates, DA; Przybytkowski, E1
Cluff, CW; Goff, WL; Johnson, WC; Wyatt, CR1
Lee, Y; Sayre, LM1
Igarashi, K; Iwasaki, S; Kashiwagi, K; Sakata, K; Sharmin, S; Shirahata, A; Ueda, S1
Igarashi, K; Kashiwagi, K; Sakata, K; Sharmin, S; Ueda, S1
Igarashi, K; Irie, Y; Kashiwagi, K; Murotani, N; Sakata, K; Sharmin, S; Ueda, S1
Casero, RA; Kensler, TW; Kwak, MK1
ALARCON, RA2
Igarashi, K; Kashiwagi, K; Ueda, S; Yoshida, K1
Igarashi, K; Ishii, I; Kashiwagi, K; Nishimura, K; Okuyama, S; Omura, T; Saiki, R1
Igarashi, K; Ikeguchi, Y; Ishii, I; Kashiwagi, K; Kojima, S; Nishimura, K; Park, H; Pegg, AE; Saiki, R; Tatsukawa, H; Toida, T; Yoshida, M1
Igarashi, K; Kashiwagi, K2
Carroll, J; Howe, K; Jagoe, WN; O'Brien, SC1
Fujii, N; Hanashima, S; Imamaki, R; Kaneda, M; Kitazume, S; Kurbangalieva, A; Oishi, S; Tanaka, K; Taniguchi, N; Tsutsui, A; Yamaguchi, Y1
Sindhu, KK1
Ando, R; Dong, Y; Dong, Z; Ishida, S; Kanda, A; Kawasaki, A; Mori, S; Murata, M; Noda, K; Saito, M; Saito, W; Yoshida, S1
Igarashi, K; Kashiwagi, K; Uemura, T1
Bing, T; Liu, X; Liu, Y; Qi, C; Shangguan, D; Shen, L; Wang, J; Wang, L; Zhang, N1
Abdullah, BM; Amin, M; Shalamanova, L; Tang, S; Taylor, RL; Whitehead, KA; Wylie, S1
Kawabe, H; Kunitomi, R; Lobsiger, N; Pradipta, AR; Tanaka, K; Zako, T1
Alford, AS; Burger, P; Casero, RA; Furbish, AB; Murray-Stewart, T; Peterson, YK; Woster, PM1
Rašková, M; Šebela, M1

Reviews

6 review(s) available for spermine and acrolein

ArticleYear
Polyamines in renal failure.
    Amino acids, 2006, Volume: 31, Issue:4

    Topics: Acrolein; Animals; Humans; Kidney Failure, Chronic; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Putrescine; Spermidine; Spermine

2006
Anticancer system created by acrolein and hydroxyl radical generated in enzymatic oxidation of spermine and other biochemical reactions.
    Medical hypotheses, 2012, Volume: 79, Issue:4

    Topics: Acrolein; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Humans; Hydroxyl Radical; Models, Biological; Neoplasms; Oxidation-Reduction; Oxidative Stress; Phosphoramide Mustards; Spermine

2012
Uremic toxins: some thoughts on acrolein and spermine.
    Renal failure, 2016, Volume: 38, Issue:10

    Topics: Acrolein; Cardiovascular Diseases; Comorbidity; Humans; Kidney Failure, Chronic; Oxidation-Reduction; Risk Factors; Spermine; Toxins, Biological; Uremia

2016
Polyamine biomarkers as indicators of human disease.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2021, Volume: 26, Issue:2

    Topics: Acrolein; Alzheimer Disease; Apoptosis; Biomarkers; Biotransformation; Cadaverine; Cell Movement; Humans; Leukocytes; Neoplasms; Periodontitis; Putrescine; Renal Insufficiency, Chronic; Spermidine; Spermine

2021
Molecular Characteristics of Toxicity of Acrolein Produced from Spermine.
    Biomolecules, 2023, 02-04, Volume: 13, Issue:2

    Topics: Acrolein; Aged; Aldehydes; Humans; Hydrogen Peroxide; Proteins; Spermine

2023
Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications.
    Molecules (Basel, Switzerland), 2023, Nov-04, Volume: 28, Issue:21

    Topics: Acrolein; Aldehydes; Polyamines; Spermidine; Spermine

2023

Other Studies

25 other study(ies) available for spermine and acrolein

ArticleYear
Evidence for serum binding of oxidized spermine and its potent G1-phase inhibition of cell proliferation.
    British journal of cancer, 1979, Volume: 39, Issue:5

    Topics: Acrolein; Animals; Blood; Cell Cycle; Cell Division; Cells, Cultured; Cricetinae; Fibroblasts; Interphase; Lymphocyte Activation; Oxidation-Reduction; Polyamines; Rats; Spermine

1979
Spermine dialdehyde, a novel ex vivo purging agent for both allogenic and autologous bone marrow transplantations.
    International journal of immunopharmacology, 1992, Volume: 14, Issue:6

    Topics: Acrolein; Animals; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Chromatography, High Pressure Liquid; Drug Stability; Leukemia, Experimental; Mice; Spermine; T-Lymphocytes; Transplantation, Autologous; Transplantation, Homologous; Tumor Cells, Cultured

1992
Inhibition of cell proliferation by polyamines does not depend on the cytotoxicity of acrolein.
    Biochemical Society transactions, 1985, Volume: 13, Issue:2

    Topics: Acrolein; Aldehydes; Animals; Cell Division; Cells, Cultured; Kinetics; Polyamines; Rats; Spermine; T-Lymphocytes

1985
Inhibition of human neutrophil locomotion by the polyamine oxidase-polyamine system.
    Immunology, 1985, Volume: 54, Issue:4

    Topics: Acrolein; Ammonia; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Humans; Hydrogen Peroxide; Neutrophils; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine

1985
Polyamine-mediated inhibition of in-vitro cell proliferation is not due to acrolein.
    Cell and tissue kinetics, 1983, Volume: 16, Issue:6

    Topics: Acrolein; Aldehydes; Animals; Cell Division; Cell Survival; Cells, Cultured; Phytohemagglutinins; Protein Biosynthesis; Rats; RNA; Spermine; T-Lymphocytes

1983
Spermine oxidation products are selectively toxic to fibroblasts in cultures of normal human prostatic epithelium.
    Cell biology international reports, 1980, Volume: 4, Issue:2

    Topics: Acrolein; Adolescent; Cells, Cultured; Epithelial Cells; Fibroblasts; Humans; Lung; Male; Middle Aged; Oxidation-Reduction; Prostate; Spermine

1980
HPLC and NMR investigation of the serum amine oxidase catalyzed oxidation of polyamines.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994, Volume: 48, Issue:1

    Topics: Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Borohydrides; Catalysis; Cattle; Chromatography, High Pressure Liquid; Fetal Blood; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Propylamines; Putrescine; Spectrometry, Mass, Fast Atom Bombardment; Spermidine; Spermine

1994
Glucose, glutathione, and cellular response to spermine oxidation products.
    Free radical biology & medicine, 1996, Volume: 20, Issue:5

    Topics: Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Buthionine Sulfoximine; Catalase; Cattle; Cell Survival; CHO Cells; Cricetinae; Glucose; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Spermine

1996
Reactive oxygen and nitrogen intermediates and products from polyamine degradation are Babesiacidal in vitro.
    Annals of the New York Academy of Sciences, 1996, Jul-23, Volume: 791

    Topics: Acrolein; Animals; Antiprotozoal Agents; Babesia bovis; Catalase; Hydrogen Peroxide; Hydroxides; Nitrites; Nitroprusside; Oxidants; Penicillamine; Polyamines; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Spermidine; Spermine; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1996
Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini.
    The Journal of biological chemistry, 1998, Jul-31, Volume: 273, Issue:31

    Topics: Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Amines; Ammonia; Animals; Blood Proteins; Cattle; Magnetic Resonance Spectroscopy; Metalloproteins; Molecular Structure; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Propylamines; Spermidine; Spermine

1998
Polyamine cytotoxicity in the presence of bovine serum amine oxidase.
    Biochemical and biophysical research communications, 2001, Mar-23, Volume: 282, Issue:1

    Topics: 3T3 Cells; Acrolein; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Cattle; Hydrogen Peroxide; Mice; Spermidine; Spermine

2001
Acrolein produced from polyamines as one of the uraemic toxins.
    Biochemical Society transactions, 2003, Volume: 31, Issue:2

    Topics: Acrolein; Biogenic Polyamines; Case-Control Studies; Cell Line; Cell Survival; Humans; Kidney Failure, Chronic; Nephritis; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Spermidine; Spermine; Uremia

2003
Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients.
    Biochemical and biophysical research communications, 2003, May-23, Volume: 305, Issue:1

    Topics: 3T3 Cells; Acrolein; Adult; Amine Oxidase (Copper-Containing); Animals; Cell Division; Enzyme Inhibitors; Female; Humans; Kidney Failure, Chronic; Male; Mice; Putrescine; Spermine

2003
Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.
    Biochemical and biophysical research communications, 2003, Jun-06, Volume: 305, Issue:3

    Topics: Acrolein; Amine Oxidase (Copper-Containing); Animals; Antioxidants; Cell Line; Culture Media; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; Enzymes; Guanidines; Keratinocytes; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidation-Reduction; Response Elements; RNA, Messenger; Signal Transduction; Spermidine; Spermine; Trans-Activators; Transcriptional Activation

2003
ISOLATION OF ACROLEIN FROM INCUBATED MIXTURES OF SPERMINE WITH CALF SERUM AND ITS EFFECTS ON MAMMALIAN CELLS.
    Archives of biochemistry and biophysics, 1964, Jul-20, Volume: 106

    Topics: Acrolein; Aldehydes; Amines; Animals; Blood; Cattle; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180; Spermine; Tissue Culture Techniques

1964
Intense correlation between brain infarction and protein-conjugated acrolein.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Acetylcysteine; Acrolein; Animals; Brain; Carrier Proteins; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Photochemistry; Rose Bengal; Spermidine; Spermine; Time Factors; Up-Regulation

2009
Brain infarction correlates more closely with acrolein than with reactive oxygen species.
    Biochemical and biophysical research communications, 2011, Jan-28, Volume: 404, Issue:4

    Topics: Acrolein; Animals; Brain Infarction; Cell Line, Tumor; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Phospholipids; Reactive Oxygen Species; RNA; Spermine

2011
Use of polyamine metabolites as markers for stroke and renal failure.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 720

    Topics: Acrolein; Aged; Animals; Biomarkers; C-Reactive Protein; Cell Line, Tumor; Cell Proliferation; Diagnostic Imaging; Disease Models, Animal; Enzyme Assays; Female; Humans; Hydrogen Peroxide; Interleukin-6; Light; Male; Mice; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Renal Insufficiency; Spermine; Stroke; Thrombosis

2011
Identification of a role for a mouse sperm surface aldo-keto reductase (AKR1B7) and its human analogue in the detoxification of the reactive aldehyde, acrolein.
    Andrologia, 2013, Volume: 45, Issue:5

    Topics: Acrolein; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Humans; Inactivation, Metabolic; Male; Mice; Spermine

2013
Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress.
    Organic & biomolecular chemistry, 2014, Jul-28, Volume: 12, Issue:28

    Topics: Acrolein; Amine Oxidase (Copper-Containing); Azocines; Cell Line, Tumor; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Guanidines; HeLa Cells; Heme Oxygenase-1; Humans; Hydrogels; Oxidative Stress; Polymerization; Spermidine; Spermine

2014
Soluble Vascular Adhesion Protein-1 Mediates Spermine Oxidation as Semicarbazide-Sensitive Amine Oxidase: Possible Role in Proliferative Diabetic Retinopathy.
    Current eye research, 2017, Volume: 42, Issue:12

    Topics: Acrolein; Aged; Amine Oxidase (Copper-Containing); Blotting, Western; Cell Adhesion Molecules; Cell Survival; Cells, Cultured; Diabetic Retinopathy; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique, Indirect; Glutathione; Humans; Hydrogen Peroxide; Lysine; Male; Middle Aged; Oxidation-Reduction; Retinal Vessels; Spermine; Vitreous Body

2017
Acrolein: An Effective Biomarker for Tissue Damage Produced from Polyamines.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1694

    Topics: Acrolein; Animals; Biomarkers; Calcium; Cell Line; Disease Models, Animal; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Hydrogen Peroxide; Male; Mice; Polyamines; Reactive Oxygen Species; Spermine; Stroke; Thrombosis

2018
Oxidative degradation of polyamines by serum supplement causes cytotoxicity on cultured cells.
    Scientific reports, 2018, 07-10, Volume: 8, Issue:1

    Topics: Acrolein; Animals; Cell Culture Techniques; Cell Line, Tumor; Cells, Cultured; Drug Resistance; Humans; Hydrogen Peroxide; Oxidation-Reduction; Polyamines; Serum; Spermidine; Spermine

2018
Inhibition of amyloid formation of amyloid β (1-42), amylin and insulin by 1,5-diazacyclooctanes, a spermine-acrolein conjugate.
    Bioorganic & medicinal chemistry, 2021, 09-15, Volume: 46

    Topics: Acrolein; Amyloid beta-Peptides; Aza Compounds; Cyclooctanes; Dose-Response Relationship, Drug; Humans; Insulin; Islet Amyloid Polypeptide; Molecular Structure; Peptide Fragments; Protein Aggregates; Spermine; Structure-Activity Relationship

2021
Identification and Characterization of Novel Small-Molecule SMOX Inhibitors.
    Medical sciences (Basel, Switzerland), 2022, 08-30, Volume: 10, Issue:3

    Topics: Acrolein; Flavins; Hydrogen Peroxide; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Spermidine; Spermine

2022