simvastatin and nb 598
simvastatin has been researched along with nb 598 in 7 studies
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Okumura, H; Sawada, M; Washizuka, Ki | 1 |
| Eda, T; Hidaka, Y; Kamei, T; Yonemoto, M | 1 |
| Hidaka, Y; Horie, M; Hotta, H; Iwasawa, Y; Kamei, T; Nagata, Y | 1 |
| Fukuzumi, H; Horie, M; Iizuka, Y; Kamei, T; Sawasaki, Y; Tsuchiya, Y; Watanabe, K | 1 |
| Horie, M; Iwasawa, Y; Kamei, T; Nagata, Y; Satoh, T; Shimizu, A | 1 |
| Hayashi, M; Horie, M; Hotta, H; Ishida, F; Kamei, T; Nagata, Y; Satoh, T | 1 |
| Gohda, M; Hanasaki, Y; Ishida, N; Itoh, H; Katsuura, K; Matzno, S; Nakamura, N; Tokunaga, T; Yamauchi, T | 1 |
Other Studies
7 other study(ies) available for simvastatin and nb 598
| Article | Year |
|---|---|
Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738.
Topics: Animals; Benzylamines; Cholesterol; Dogs; Enzyme Inhibitors; Humans; In Vitro Techniques; Microsomes, Liver; Oxygenases; Rats; Squalene Monooxygenase; Structure-Activity Relationship; Triglycerides; Tumor Cells, Cultured | 2004 |
Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733).
Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Benzylamines; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Fibrinogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Nifedipine; Platelet-Derived Growth Factor; Pravastatin; Simvastatin; Sterols; Swine; Thiophenes | 1992 |
Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes | 1991 |
Hypolipidemic effects of NB-598 in dogs.
Topics: Animals; Anticholesteremic Agents; Benzylamines; Bile; Bile Acids and Salts; Cholesterol; Dogs; Feces; Lipids; Lipoproteins; Lovastatin; Male; Oxygenases; Phospholipids; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides | 1991 |
Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells.
Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Benzylamines; Cell Line; Cell Membrane; Cholesterol; Cholesterol Esters; Enzyme Activation; Humans; Linoleic Acids; Lipids; Lovastatin; Microsomes; Oleic Acid; Oleic Acids; Oxygenases; Polyunsaturated Alkamides; Simvastatin; Squalene Monooxygenase; Sterol O-Acyltransferase; Thiophenes; Tritium; Tumor Cells, Cultured | 1993 |
An inhibitor of squalene epoxidase, NB-598, suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells.
Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Benzylamines; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Oxygenases; Simvastatin; Squalene; Squalene Monooxygenase; Thiophenes; Triglycerides; Tumor Cells, Cultured | 1993 |
Inhibition of cholesterol biosynthesis by squalene epoxidase inhibitor avoids apoptotic cell death in L6 myoblasts.
Topics: Actins; Animals; Apoptosis; Benzylamines; Cell Differentiation; Cell Line; Cholesterol; DNA Fragmentation; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Fibers, Skeletal; Oxygenases; Rats; Simvastatin; Squalene Monooxygenase; Thiophenes | 1997 |