sesamin and lignans
sesamin has been researched along with lignans in 396 studies
Research
Studies (396)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (0.76) | 18.7374 |
| 1990's | 32 (8.08) | 18.2507 |
| 2000's | 85 (21.46) | 29.6817 |
| 2010's | 199 (50.25) | 24.3611 |
| 2020's | 77 (19.44) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fujiyama-Fujiwara, Y; Igarashi, O; Umeda, R | 1 |
| Katayama, K; Namiki, M; Nohara, Y; Yamashita, K | 1 |
| Akimoto, K; Hirose, N; Inoue, T; Nishihara, K; Shimizu, S; Sugano, M; Yamada, H | 1 |
| Akimoto, K; Kawashima, H; Shimizu, S; Shinmen, Y; Sugano, M; Yamada, H | 1 |
| Chen, J; Chen, SF; Geng, GL; He, CH; Xi, FD; Ye, GH; Zheng, QT | 1 |
| Arima, Y; Hayakawa, R; Hosokawa, K; Matsunaga, K; Shin, CS; Suzuki, M; Yoshida, M | 1 |
| Fujiyama-Fujiwara, Y; Igarashi, O; Kuzuyama, M; Umeda-Sawada, R | 1 |
| Akimoto, K; Furuya, M; Kita, S; Matsumura, Y; Morimoto, S; Oka, N; Tanaka, T | 2 |
| Appelqvist, LA; Kamal-Eldin, A; Pettersson, D | 1 |
| Hirose, N; Makino, T; Ogawa, T; Sugano, M | 1 |
| Akamatsu, T; Akimoto, K; Hirose, N; Kitagawa, Y; Shimizu, S; Sugano, M; Yamada, H | 1 |
| Murakami, T; Ogawa, H; Sasagawa, S; Shimizu, S; Yamada, H; Yoshizumi, H | 1 |
| Akimoto, K; Kawashima, H; Shimizu, S; Shirasaka, N | 1 |
| Iizuka, Y; Imai, T; Namiki, M; Yamashita, K | 1 |
| Gu, JY; Lim, BO; Nonaka, M; Sugano, M; Tsujita, A; Wakizono, Y; Yamada, K | 1 |
| Igarashi, O; Takahashi, N; Umeda-Sawada, R | 1 |
| Fujita, K; Hirata, F; Hosoda, K; Ishikawa, T; Ishikura, Y; Nakamura, H | 1 |
| Akimoto, K; Asami, S; Hirose, N; Kitagawa, Y; Nakabayashi, A; Shimizu, S; Sugano, M; Suwa, Y; Yamada, H | 1 |
| Igarashi, O; Ogawa, M; Okada, Y; Umeda-Sawada, R | 1 |
| Murakami, T; Ogawa, H; Sasagawa, S; Yoshizumi, H | 1 |
| Iizuka, Y; Namiki, M; Nonaka, M; Sugano, M; Yamashita, K | 1 |
| Hamano, T; Konoshima, T; Takasaki, M; Tokuda, H; Yasuda, I | 1 |
| Chavali, SR; Forse, RA; Utsunomiya, T; Zhong, WW | 2 |
| Chavali, SR; Forse, RA; Zhong, WW | 1 |
| Akimoto, K; Kita, S; Matsumura, Y; Morimoto, S; Taguchi, Y; Tanaka, T; Tanida, Y | 1 |
| Igarashi, O; Ogawa, M; Umeda-Sawada, R | 2 |
| Dohi, A; Gu, JY; Nonaka, M; Sugano, M; Wakizono, Y; Yamada, K | 1 |
| Fukuda, N; Ide, T; Jayasooriya, AP; Miyagi, C; Sakono, M; Sugano, M; Yamamoto, K; Zhang, L | 1 |
| Kang, MH; Kawai, Y; Naito, M; Osawa, T | 1 |
| Aoyama, T; Ashakumary, L; Fukuda, N; Hashimoto, T; Ide, T; Mizugaki, M; Rouyer, I; Sugano, M; Takahashi, Y | 1 |
| Fukuda, N; Ide, T; Kodama, M; Sakono, M; Sugano, M; Yamamoto, K; Zhang, L | 1 |
| Higuti, N; Kagaya, M; Kiso, Y; Yamashita, K | 1 |
| Hibasami, H; Imai, K; Ishi, Y; Katsuzaki, H; Komiya, T; Miyahara, Y; Nakagawa, M | 1 |
| Basu, S; Frank, J; Kamal-Eldin, A; Razdan, A; Tengblad, S; Vessby, B | 1 |
| Kita, S; Matsumura, Y; Ohgushi, R; Okui, T | 1 |
| Parker, RS; Sontag, TJ; Swanson, JE | 1 |
| Ahsan, M; Hasan, CM; Islam, SK; Ito, C; Zaman, TA | 1 |
| Chatrattanakunchai, S; Fraser, T; Stobart, K | 1 |
| Gupta, MM; Kumar, S; Prajapati, V; Srivastava, S; Tripathi, AK | 1 |
| Ide, T; Katsuta, M; Okuyama, Y; Sirato-Yasumoto, S; Takahashi, Y | 1 |
| Igarashi, O; Nakamura, M; Ogawa, M; Umeda-Sawada, R | 1 |
| Azambuja, P; Cabral, MM; Garcia, ES; Gottlieb, OR | 1 |
| Lewis, NG; Marchand, PA; Zajicek, J | 1 |
| Bataille, CJ; Brown, RC; Bruton, G; Hinks, JD; Swain, NA | 1 |
| Cooney, RV; Custer, LJ; Franke, AA; Okinaka, L | 1 |
| Ashakumary, L; Fukuda, N; Ide, T; Kushiro, M; Sugano, M; Takahashi, Y | 1 |
| Hara, H; Ikeda, K; Kakuta, H; Nara, Y; Noguchi, T; Sasaki, Y; Seki, J; Yamagata, K; Yamamoto, J; Yamori, Y | 1 |
| Akahoshi, A; Goto, Y; Koba, K; Matsuyama, H; Miyazaki, T; Murao, K; Nonaka, M; Okumura, T; Sugano, M; Tanaka, K; Yamada, K; Yamasaki, M | 1 |
| Guin, C; Rana, KK; Roy, SC | 1 |
| Itoh, C; Kiso, Y; Matsumura, Y; Nakano, D; Takaoka, M; Tanaka, T | 1 |
| Wang, Y; Zhang, SY; Zhou, BJ | 1 |
| Ni, X; Qiao, L; Yan, Y; Ye, M | 1 |
| Akimoto, K; Harada, M; Kiso, Y; Miki, W; Nakahara, K; Nakai, M; Shibata, H | 1 |
| Fujita, M; Fukuda, N; Iwata, T; Kasai, M; Miyanaga, F; Sakono, M; Sugano, M; Tamaru, S; Tsutsumi, K; Yuji, K | 1 |
| Fushiki, T; Ikeda, T; Kiso, Y; Moritani, T; Nishijima, Y; Ohnuki, K; Shibata, H | 1 |
| Hou, RC; Huang, HM; Jeng, KC; Tzen, JT | 1 |
| LINGNER, K; VON BRUCHHAUSEN, F | 1 |
| Frank, J; Kamal-Eldin, A; Lundh, T; Parker, RS; Swanson, JE; Vessby, B | 1 |
| Higuchi, N; Ikeda, S; Kagaya, M; Kiso, Y; Kobayashi, K; Tohyama, T; Yamashita, K | 1 |
| Ishii, F; Itoh, C; Kawanishi, H; Kiso, Y; Matsumura, Y; Nakano, D; Takaoka, M; Tanaka, T; Tsuruoka, N | 1 |
| Igarashi, O; Mizukuchi, A; Umeda-Sawada, R | 1 |
| Arumughan, C; Jayalekshmy, A; Suja, KP | 1 |
| Abe, H; Fujiwara, Y; Seyama, Y; Umeda-Sawada, R | 1 |
| Ide, T; Kushiro, M; Takahashi, Y | 1 |
| Bortoli, SA; Lopes, LM; Murata, AT; Nascimento, IR | 1 |
| Hong, DD; Ide, T; Kushiro, M; Ranasinghe, P; Sugano, M; Takahashi, Y | 1 |
| Azambuja, P; Garcia, ES | 1 |
| Hou, RC; Jeng, KC; Wu, CC; Yang, CH | 1 |
| Hemalatha, S; Raghunath, M | 1 |
| Chen, PR; Chen, WW; Lee, CC; Lin, S; Shyu, KG; Tsai, CE; Tsai, SC; Wang, BW | 1 |
| Hou, RC; Jeng, KC; Ping, LI; Wang, JC | 1 |
| Kiso, Y | 1 |
| Fukumoto, S; Miyake, Y; Nakamura, Y; Okada, M; Osawa, T; Sakaida, K | 1 |
| Fujikawa, T; Hayashi, I; Kanada, N; Nakashima, K; Ogata, M; Shimada, A; Suzuki, I | 1 |
| Ikeda, K; Noguchi, T; Sasaki, Y; Yamamoto, J; Yamori, Y | 1 |
| Abe, K; Kidokoro, A; Kiso, Y; Matsumoto, I; Tsuruoka, N | 2 |
| Frank, J; Kamal-Eldin, A; Traber, MG | 1 |
| Hsieh, TJ; Lu, LH; Su, CC | 1 |
| Adlercreutz, H; Aura, AM; Heinonen, SM; Peñalvo, JL | 1 |
| Chow, TJ; Li, CY; Wu, TS | 1 |
| Lee, CP; Yen, GC | 1 |
| Arachchige, PG; Ide, T; Takahashi, Y | 1 |
| Liu, Z; Saarinen, NM; Thompson, LU | 1 |
| Fujii, K; Ikemura, K; Kiso, Y; Kwak, CJ; Matsumura, Y; Nakai, M; Nakano, D; Ohkita, M; Ono, Y; Satake, A; Takaoka, M; Tomimori, N | 1 |
| Kageyama, N; Miki, W; Nakahara, K; Nakai, M | 1 |
| Guan, ZZ; Lu, SF; Nie, HG; Yang, BF; Zhang, LL; Zhang, S | 1 |
| Fukuchi-Mizutani, M; Fukui, Y; Katsuta, M; Nakai, M; Ono, E; Saito, M; Satake, H; Tanaka, T; Tanaka, Y; Tomimori, N; Umezawa, T | 1 |
| Adlercreutz, H; Hopia, A; Peñalvo, JL | 1 |
| Adachi, Y; Ide, T; Lim, JS; Takahashi, Y | 1 |
| Argyropoulos, DS; Coletta, M; Crestini, C; Fiani, C; Marini, S; Saladino, R | 1 |
| Andersson, RE; Kamal-Eldin, A; Moazzami, AA | 1 |
| Baker, JL; Bayman, P; Campbell, BC; Choi, WS; Lee, SE; Park, BS | 1 |
| Enoki-Konishi, M; Hitomi, T; Kawanaka, M; Koyama, M; Matsuzaki, Y; Nishikawa, A; Nishino, H; Okuyama, Y; Osawa, T; Sakai, T; Takayasu, J; Yokota, T | 1 |
| Ge, T; Li, Q; Tan, H; Yan, G | 1 |
| Kiso, Y; Kurumazuka, D; Matsumura, Y; Nagai, Y; Nakano, D; Nishiyama, A | 1 |
| Bae, H; Han, AR; Hong, M; Kim, HJ; Kim, YS; Shin, M | 1 |
| Grougnet, R; Lazarou, D; Magiatis, P; Papadakis, EN; Papadopoulos, AI; Papadopoulou-Mourkidou, E; Skaltsounis, AL | 1 |
| Arimboor, R; Arumughan, C; Sukumar, D | 1 |
| Ishikawa, T; Kiso, Y; Obayashi, M; Ono, Y; Yamada, Y; Yamashita, K | 1 |
| Brännäs, E; Gjøen, T; Kamal-Eldin, A; Larsson, P; Moazzami, A; Pickova, J; Ruyter, B; Trattner, S; Zlabek, V | 1 |
| Gjøen, T; Kamal-Eldin, A; Pickova, J; Ruyter, B; Trattner, S; Zlabek, V; Østbye, TK | 1 |
| Chang, CY; Chen, JR; Chen, YL; Huang, CC; Huang, GC; Li, JS; Tsi, D; Yang, SC | 1 |
| Kiso, Y; Matsumura, Y; Nishioka, Y; Ono, Y; Tobashi, T; Tomimori, N; Urata, H; Wada, S | 1 |
| Chen, JF; Chen, JJ; Chung, CY; Hwang, TL | 1 |
| Anagnostis, A; Papadopoulos, AI | 1 |
| Chen, X; Lu, F; Nie, J; Wang, K; Xiao, M; Yang, D | 1 |
| Aono, H; Kiso, Y; Maeda, H; Miyawaki, T; Moriyama, K; Toyoda-Ono, Y | 1 |
| Fujita, Y; Hamada, N; Ito, M; Kiso, Y; Kitagawa, Y; Naoi, M; Nozawa, Y; Ono, Y; Tanaka, A; Tomimori, N | 1 |
| Li, M; Peng, Y; Rustum, AM; Wang, X | 1 |
| Guo, LQ; Huang, K; Kong, X; Wu, XQ; Xiong, Y; Yang, JR; Zhou, Y | 1 |
| Liu, X; Osawa, T; Yamada, N | 2 |
| Barden, AE; Clarke, MW; Croft, KD; Hodgson, JM; Indrawan, AP; Puddey, IB; Wu, JH | 1 |
| Ahmad, A; Ahmad, S; Hoda, MN; Ishrat, T; Islam, F; Khan, MB; Khan, MM; Khuwaja, G; Raza, SS; Srivastava, P | 1 |
| Kim, HJ; Kobayashi, A; Morimoto, K; Okazawa, A; Ono, E; Satake, H; Yamagaki, T | 1 |
| Choe, J; Chung, BH; Ha, KS; Jeoung, D; Kim, JD; Kim, YM; Kwon, YG; Lee, H; Lee, JJ | 1 |
| Lee, IT; Lee, SD; Lee, WJ; Lin, LY; Lin, SY; Ou, HC; Sheu, WH; Tsai, KL; Wu, CM | 1 |
| Yang, B; Yu, B; Zhang, G; Zhang, L | 1 |
| Chen, J; Cui, Y; Hou, X; Le, Y; Xie, L; Yang, L | 1 |
| Deng, B; Ge, YH; Hao, XJ; Jiang, CY; Mu, SZ; Zhang, JX | 1 |
| Croft, KD; Hime, N; Hodgson, JM; Loke, WM; Magat, M; McKinley, AJ; Proudfoot, JM; Stocker, R | 1 |
| Ibe, M; Okura, T; Shinozuka, K; Umegaki, K; Yamada, S | 1 |
| Chen, YL; Chien, HF; Huang, CJ; Kao, CH; Kao, YS; Kuan, II; Liang, CJ; Wang, SH; Wu, PJ; Wu, WH | 1 |
| Aggarwal, BB; Guha, S; Harikumar, KB; Joy, B; Krishnan, S; Pandey, MK; Sung, B; Tharakan, ST | 1 |
| Chang, HC; Chen, CY; Cheng, KC; Hsueh, MC; Lee, AY; Wang, HM | 1 |
| Chang, CC; Huang, TS; Lee, CC; Lin, SJ; Liu, KJ; Wu, YC | 1 |
| Groundwater, P; He, CY; Li, PY; Liu, JP; Lu, D; Yan, ZW | 1 |
| Ikushiro, S; Kamakura, M; Ohta, M; Sakaki, T; Yasuda, K | 1 |
| Fujii, W; Hori, H; Kamada, Y; Kitagawa, Y; Nagao, M; Ono, Y; Sakakibara, Y; Shibata, H; Shimoyoshi, S; Takayanagi, T | 1 |
| Brännäs, E; Gjoen, T; Kamal-Eldin, A; Moazzami, A; Ostbye, TK; Pan, J; Pickova, J; Ruyter, B; Trattner, S; Zlabek, V | 1 |
| Chang, HW; Cheng, KC; Chiu, CC; Fang, WC; Hsu, CH; Hsu, SW; Hsu, TF; Lee, AY; Lin, CJ; Wang, HM | 1 |
| Akao, Y; Fujita, Y; Hamada, N; Ito, M; Itoh, T; Kiso, Y; Kitagawa, Y; Nozawa, Y; Ono, Y; Tanaka, A; Tomimori, N | 1 |
| Kiso, Y; Ono, Y; Rogi, T; Tomimori, N | 1 |
| Kobayashi, D; Kuribayashi, K; Tanabe, H; Tanaka, M; Tsuji, N; Watanabe, N | 1 |
| Hyodo, K; Katsuta, M; Kinugasa, C; Naemura, A; Nakai, Y; Yamamoto, J | 1 |
| Chang, MH; Chao, YY; Hou, CW; Hsieh, PF; Jeng, KC; Lin, CH; Peng, YF; Shen, ML; Wu, SP; Yao, PW | 1 |
| Ikushiro, S; Kamakura, M; Munetsuna, E; Ohta, M; Sakaki, T; Yasuda, K | 1 |
| Deng, P; He, G; Huang, J; Jiang, Z; Li, S; Liu, Y | 1 |
| Erben, U; Freise, C; Kim, KY; Ruehl, M; Seehofer, D; Somasundaram, R; Trowitzsch-Kienast, W; Zeitz, M | 2 |
| Sakaki, T; Yasuda, K | 1 |
| Mráz, J; Pickova, J; Ruyter, B; Schiller Vestergren, AL; Trattner, S | 1 |
| Chen, JM; Thompson, LU; Truan, JS | 1 |
| Choi, HS; Lee, HJ; Lee, MK; Lim, SC; Park, HJ; Park, KH; Zhang, M | 1 |
| Pickova, J; Vestergren, AS; Zamaratskaia, G; Zlabek, V | 1 |
| Haber, WA; Moriarity, DM; Setzer, WN; Vogler, B; Walker, TM | 1 |
| Huang, K; Kong, X; Li, XL; Wu, XQ; Yang, JR; Zhou, Y | 1 |
| Ide, T; Kawashima, H; Kiso, Y; Ono, Y | 1 |
| Wu, XQ; Yang, JR | 1 |
| Bournival, J; Francoeur, MA; Martinoli, MG; Renaud, J | 1 |
| Chen, TY; Chiu, HF; Tzeng, YT; Wang, CK | 1 |
| Boonmaleerat, K; Kongtawelert, P; Pothacharoen, P; Reutrakul, V; Wanachewin, O | 1 |
| Kiso, Y; Kitagawa, Y; Nakai, M; Ono, Y; Shibata, H; Tomimori, N | 1 |
| Caterson, B; Kongtawelert, P; Phitak, T; Poompimol, W; Pothacharoen, P; Settakorn, J | 1 |
| Ikushiro, S; Itoh, T; Kamakura, M; Munetsuna, E; Ohta, M; Sakaki, T; Wakayama, S; Yamamoto, K; Yasuda, K | 1 |
| Azechi, A; Ide, T; Kitade, S; Kunimatsu, Y; Nakajima, C; Suzuki, N | 1 |
| Kamal-Eldin, A; Pickova, J; Rosenlund, G; Schiller Vestergren, A; Trattner, S; Wagner, L | 1 |
| Baxter, LL; Incao, A; Marugan, JJ; McKew, JC; Pavan, WJ; Xiao, J; Zheng, W | 1 |
| Bournival, J; Martinoli, MG; Plouffe, M; Provencher, C; Renaud, J | 1 |
| Akl, MR; Ayoub, NM; Sylvester, PW | 1 |
| Baluchnejadmojarad, T; Dariani, S; Jalali Nadoushan, MR; Kalalian-Moghaddam, H; Raoufi, S; Roghani, M; Roghani-Dehkordi, F; Vaez Mahdavi, MR | 1 |
| Trattner, S; Wagner, L; Zamaratskaia, G; Zlabek, V | 1 |
| Inoue, A; Kitamura, C; Matsuoka, Y; Monda, A; Ohashi, K; Ohnishi, M; Shibuya, H; Takemoto, R | 1 |
| Kong, X; Li, WX; Yang, JR; Zhang, JX | 1 |
| Hong, L; Juncheng, H; Liangliang, C; Qin, W; Xiaoxiang, Z; Yi, W | 1 |
| Abuasal, BS; Akl, MR; Ayoub, NM; Kaddoumi, A; Sylvester, PW | 1 |
| Jones, PG; Kumar, A; Matsunami, K; Negi, DS; Negi, N; Schulz, S | 1 |
| Chan, HY; Chen, ZY; Huang, Y; Liang, Y; Ma, KY; Peng, C; Zuo, Y | 1 |
| Harada, M; Kiso, Y; Nakai, M; Ogata, T; Ono, Y; Shibata, H; Tada, M | 1 |
| Chao, C; Liu, CM; Ming, QL; Sun, JM; Zheng, GH | 1 |
| Bae, JS; Kim, JA; Ku, SK; Lee, T; Lee, W | 1 |
| Alhazzaa, R; Bridle, AR; Carter, CG; Nichols, PD | 1 |
| Guo, S; Han, J; Lei, H; Sun, H; Wang, Q; Zhang, X | 1 |
| Chen, GX; Kong, X; Li, WX; Tang, LJ; Yang, H; Yang, JR; Zhang, JX | 1 |
| Borralho, PM; Ferreira, MJ; Luo, X; Mansoor, TA; Mulhovo, S; Rodrigues, CM | 1 |
| Bai, G; Cao, XL; Liu, Y; Tang, YL; Xiang, JF; Xu, J; Zhang, H | 1 |
| Hanzawa, F; Ikeda, S; Nomura, S; Sakuma, E; Uchida, T | 1 |
| Bae, JS; Han, CK; Ku, SK; Lee, W; Yoo, H | 1 |
| Han, Y; Ma, Y; Wang, S; Xu, K | 1 |
| Fujii, W; Kitagawa, Y; Sakakibara, Y; Shibata, H; Tanaka, Y; Tomimori, N | 1 |
| Chen, L; Chen, M; Deng, P; Du, Y; He, G; Wang, C; Yan, X; Yang, G | 1 |
| Liu, J; Wu, W; Xie, Y; Yang, Y | 1 |
| Gómez-Requeni, P; Moazzami, AA; Pickova, J; Trattner, S; Wagner, L | 1 |
| Guo, H; Li, J; Li, Q; Liu, Y; Niu, Y; Su, S; Wang, Y; Xiong, C; Zhang, R; Zhao, L | 1 |
| Bae, JS; Han, CK; Kim, JA; Ku, SK | 1 |
| Ding, J; Liu, CM; Ma, JQ; Zhang, L | 1 |
| Kongtawelert, P; Mizumoto, S; Najarus, S; Pothacharoen, P; Settakorn, J; Sugahara, K | 1 |
| Frank, J; Graeve, L; Grebenstein, N; Schumacher, M | 1 |
| Górnaś, P; Pugajeva, I; Segliņa, D; Siger, A | 1 |
| Chen, YL; Chuang, SH; Hou, CW; Jeng, KC; Wang, JS | 1 |
| Kage-Nakadai, E; Kashima, N; Komura, T; Nishikawa, Y; Saeki, S; Tamura, M; Terao, K; Yaguchi, Y | 1 |
| Efferth, T; Khalid, H; Saeed, M; Sugimoto, Y | 1 |
| Bastos, M; Batista, D; Custódio, L; Martins, A; Mignon, R; Neng, NR; Nogueira, JM; Rauter, AP; Varela, J; Vizetto-Duarte, C | 1 |
| Bussey, RO; Carter, FS; Cech, NB; Falkinham, JO; Figueroa, M; Oberlies, NH; Sy-Cordero, AA | 1 |
| Huang, YS | 1 |
| Chang, H; Chen, YS; Chiang, HM; Hou, CW; Jeng, KC; Wang, JS; Yao, PW | 1 |
| Kao, ST; Lee, CC; Lin, CH; Shen, ML; Wu, DC; Zhou, N | 1 |
| Araújo, AL; Chibli, LA; de Araújo, Ada L; de Sousa, OV; Del-Vechio-Vieira, G; do Amaral, Mda P; Monteiro, EM; Pereira, MC; Pinto, MA; Rodarte, MP; Silvério, MS; Vilela, FM; Yamamoto, CH | 1 |
| Guo, P; Liu, N; Sun, L; Wu, C; Zheng, J | 1 |
| Liu, M; Liu, Q; Liu, YQ; Pan, WW; Pei, G; Peng, CY; Yang, SH | 1 |
| Kao, ST; Lin, CH; Shen, ML; Wu, DC | 1 |
| Gong, W; Guo, LQ; Kong, X; Ma, MZ; Quan, ZW; Su, Q; Wang, GD; Weng, MZ; Yang, JR; Zhang, JX; Zhang, Y | 1 |
| Chang, SY; Hou, CW; Jeng, KC | 1 |
| Chen, LY; Kang, GJ; Yang, SJ; Yang, ZM; Zhou, HY | 1 |
| Chao, D; Chen, YS; Hsieh, CC; Hung, CH; Kuo, CH; Kuo, HF; Lee, MS; Wang, SL | 1 |
| Jan, KC; Liu, TC; Yang, BB | 1 |
| Guo, H; Liu, Y; Niu, Y; Tian, J; Wang, L; Zhang, H; Zhang, R; Zhao, L | 1 |
| Egusa, K; Fukunaga, M; Inoue, A; Kawakami, T; Motomura, M; Ohnishi, M; Shiratsuchi, A; Takahashi, M; Urasaki, T | 1 |
| Freise, C; Querfeld, U | 1 |
| Ahmad, S; Ali, M; Bhatia, K; Elsherbiny, NM; Haque, R; Ishrat, T; Jamal, A; Katare, DP; Khan, MB; Khan, MM; Liou, GI; Shah, ZA | 1 |
| Chen, F; Chen, X; Fu, G; Li, H; Wan, Y; Xie, M | 1 |
| Ren, Y; Wu, Y; Yang, J; Zhao, M; Zheng, S | 1 |
| Pickova, J; Trattner, S; Vestergren, AS; Wagner, L; Zamaratskaia, G; Zlabek, V | 1 |
| Chen, J; Chen, ZY; Huang, Y; Jiao, R; Lei, L; Liang, YT; Liu, Y; Ma, KY; Peng, C; Wang, X; Zuo, Y | 1 |
| Azechi, A; Ide, T; Kitade, S; Kunimatsu, Y; Nakajima, C; Ogata, N; Suzuki, N | 1 |
| Bhaduri, A; Bhat, KV; Pathak, N; Rai, AK | 1 |
| Bai, X; Chen, Y; Gu, J; Li, X; Lili, Z; Wang, X; Wang, Z; Zhang, D; Zhang, G; Zhang, L | 1 |
| Kong, X; Li, W; Ren, Y; Wu, Y; Xuan, J; Yang, J; Zhao, M; Zheng, S | 1 |
| Guo, HL; Li, XB; Liu, SB; Tian, Z; Wang, DS; Wang, XS; Xiao, Y; Zhang, ZW; Zhao, MG | 1 |
| Mendyk, E; Smolarz, HD; Załuski, D | 1 |
| Majdalawieh, AF; Ro, HS | 1 |
| Cai, F; Guo, L; Liu, X; Xu, P | 1 |
| Chen, R; Gong, X; Jiang, R; Kuang, G; Ma, L; Wan, J | 1 |
| Schwertner, HA; Stankus, JJ | 1 |
| Ichikawa, H; Nishiwaki, H; Shuto, Y; Yamauchi, S | 1 |
| Hou, CW; Jeng, KC; Kao, YH; Siao, AC | 1 |
| Chen, XP; Guo, LQ; Kong, X; Li, W; Liu, WY; Yang, JR; Zhang, JX | 1 |
| Deng, RY; Guo, LQ; Kong, X; Ma, MZ; Su, Q; Wang, GD; Yang, JR; Zhang, JX | 1 |
| Hasegawa, K; Hieda, K; Katanasaka, Y; Morimoto, T; Sunagawa, Y | 1 |
| Liu, L; Lv, D; Zhu, CQ | 1 |
| Han, JH; Jung, SH; Kim, YH; Lee, JJ; Lee, SG; Myung, CS; Park, HS | 1 |
| Gao, YX; Li, S; Li, XW; Yang, JR | 1 |
| Kim, JH; Lee, JK | 1 |
| Fukushima, A; Furihata, T; Kinugawa, S; Matsushima, S; Mizushima, W; Okita, K; Ono, Y; Shibata, H; Takada, S; Takemoto, D; Tsutsui, H; Yokota, T | 1 |
| Cao, J; Chen, J; Feng, C; Song, J; Wang, J; Xie, L | 1 |
| Ahn, S; Chun, HS; Jin, G; Kim, BH; Kim, J; Lee, Y | 1 |
| Monzote, L; Piñón, A; Pulivarthi, D; Setzer, WN; Steinberg, KM | 1 |
| Fanhchaksai, K; Kodchakorn, K; Kongtawelert, P; Pothacharoen, P | 1 |
| Chen, L; Chen, X; Ying, X; Zhang, W; Zhang, Y | 1 |
| Jian-An, W; Libing, J; Qiang, L; Shouyin, J; Yuan, J; Yulin, L | 1 |
| Li, G; Li, LC; Lin, ZH; Piao, HM; Yan, GH; Zheng, MY | 1 |
| Arakawa, H; Kanagawa, M; Ogihara, T; Otsuka, K; Tomono, T; Yano, K | 1 |
| Kong, X; Ren, YN; Tao, SJ; Yang, JR; Zhao, MQ; Zheng, SG | 1 |
| Cho, IJ; Jeon, JS; Kim, CY; Kim, YM; Park, CL; Syed, AS | 1 |
| Jiang, XM; Liao, DF; Wang, W; Wang, YQ; Wang, Z; Yan, JY | 1 |
| Li, K; Li, Y; Mao, L; Xu, B; Zhao, J | 1 |
| Cheng, Y; Deng, J; Han, B; Luo, X; Yang, H; Yu, Y; Zhang, C; Zhang, J; Zhang, R | 1 |
| Ahmad, S; AlQahtani, MH; Alzahrani, FA; Bhatia, K; ElSherbiny, NM; Haque, R; Jamal, MS; Khan, R; Liou, GI; Zaidi, SK | 1 |
| Khongchai, P; Phuwapraisirisan, P; Surachaitanawat, N; Worawalai, W | 1 |
| Boonmaleerat, K; Khansai, M; Kongtawelert, P; Phitak, T; Pothacharoen, P | 1 |
| Fujiki, E; Hashimoto, Y; Kobayashi, M; Kumano, T | 1 |
| Akiyama, H; Inoue, K; Nakagawa, K; Nishizaki, Y; Sato, K; Sugimoto, N; Takahashi, M; Takeuchi, H | 1 |
| Cheng, Y; Han, B; Hu, S; Luo, X; Yang, H; Yu, Y; Zhang, J; Zhang, R | 1 |
| Maruyama, W; Naoi, M; Osawa, T; Shamoto-Nagai, M; Wu, Y | 1 |
| Bai, Y; Chen, X; Dai, X; Ding, J; Ding, X; Li, P; Wu, L; Yu, L; Zhou, H | 1 |
| Eitsuka, T; Miyazawa, T; Nakagawa, K; Nishida, H; Tatewaki, N | 1 |
| Bhatt, V; Kumar, N; Sharma, S; Sharma, U; Singh, B | 1 |
| Cho, YJ; Kim, KS; Lee, KE; Lee, MK; Park, HJ; Shin, KS; Zhao, TT | 1 |
| Kim, HJ; Kim, KS; Lee, KE; Lee, MK; Park, HJ; Shin, KS; Zhao, TT | 1 |
| Bao, HX; Ferns, K; Kou, JJ; Li, D; Li, QH; Li, T; Liu, H; Liu, SL; Wang, X; Yan, ZQ; Yin, L; Yin, SY; Zeng, Z; Zhao, ZY; Zhou, YJ | 1 |
| Chen, G; Ji, Y; Jiang, A; Kong, P; Song, C; Wang, G; Wang, Y; Xi, C; Yan, J; Zhuang, J | 1 |
| Rogi, T; Shibata, H; Tomimori, N | 1 |
| Lee, KE; Lee, MK; Park, HJ; Shin, KS; Yi, BR; Zhao, TT | 1 |
| Amano, S; Ide, T; Iwase, H; Sunahara, S; Tachihara, A; Watanabe, T; Yagi, M | 1 |
| Ramaprasad, TR; Sadashivaiah, B; Singh, SA; Yashaswini, PS | 1 |
| Kawaguchi, K; Kiyama, R; Zhu, Y | 1 |
| Baluchnejadmojarad, T; Ghalami, J; Mansouri, M; Mokhtari, Z; Roghani, M | 1 |
| Kage-Nakadai, E; Komura, T; Nakadai, M; Nakatani, Y; Nishikawa, Y; Terao, K; Yaguchi, Y | 1 |
| Do, YY; Huang, PL; Lin, YC; Phan, NN; Thuy, TD; Wang, CY; Wang, SY; Yu, HG | 1 |
| Lee, KE; Lee, KS; Lee, MK; Park, HJ; Zhao, TT | 1 |
| Aungsuchawan, S; Boonma, N; Keawdee, J; Laowanitwattana, T; Markmee, R; Narakornsak, S; Peerapapong, L; Poovachiranon, N; Pothacharoen, P; Tancharoen, W; Tasuya, W; Thaojamnong, C | 1 |
| Halsne, R; Pilipenko, N; Ropstad, E; Zamaratskaia, G | 1 |
| Kongtawelert, P; Pothacharoen, P; Pruksakorn, D; Srisuthtayanont, W | 1 |
| Fan, D; Jin, YG; Tang, QZ; Wu, QQ; Xu, M; Yang, Z; Yuan, Y | 1 |
| Chen, H; Ding, J; Liu, YL; Tian, HL; Xu, ZM; Yang, DX; Yang, GY; Yuan, F | 1 |
| Chen, H; Ding, J; Liu, Y; Tian, H; Xu, Z; Yang, D; Yuan, F | 1 |
| Hori, H; Kitagawa, Y; Ono, Y; Shibata, H; Tomimori, N | 1 |
| Kongtawelert, P; Phitak, T; Pothacharoen, P; Wanachewin, O | 1 |
| Chen, DN; Chen, YJ; Gao, YJ; Jiang, L; Li, J; Liu, WJ; Wu, YP; Zhong, WJ | 1 |
| Majdalawieh, AF; Massri, M; Nasrallah, GK | 1 |
| Fanhchaksai, K; Khansai, M; Klangjorhor, J; Kongtawelert, P; Phitak, T; Pothacharoen, P; Udomrak, S | 1 |
| Deng, W; Fan, D; Jin, YG; Liao, HH; Liu, FY; Ni, J; Tang, QZ; Wu, QQ; Xu, M; Yang, Z; Yuan, Y; Zhang, N | 1 |
| Azuma, T; Horikawa, M; Mizutani, M; Mori, S; Murata, J; Nagano, AJ; Nakayasu, M; Ono, E; Shiraishi, A; Tera, M; Toyonaga, H; Wakasugi, T; Yamamoto, MP; Yoroizuka, S | 1 |
| Doran, O; Pilipenko, N; Rasmussen, MK; Zamaratskaia, G | 1 |
| Arumugam, N; Bhandare, VV; Cavuturu, BM; Ramaswamy, A | 1 |
| Imai, A; Ito, N; Miyazawa, T; Nakagawa, K; Oda, Y; Seki, S; Ueda, F | 1 |
| Ikushiro, S; Nishikawa, M; Sakaki, T; Yasuda, K | 1 |
| Dou, H; Hu, Y; Li, X; Liu, L; Xu, D; Yang, S | 1 |
| Asada, T; Ito, N; Saito, H; Seki, S; Ueda, F | 1 |
| Abu Farkh, B; Abu-Lafi, S; Barriah, W; Makhamra, S; Nasser, A; Rayan, A; Rayan, I | 1 |
| D'Auria, M; Mecca, M; Todaro, L | 2 |
| Bunargin, W; Keowkase, R; Shoomarom, N; Sitthithaworn, W; Weerapreeyakul, N | 1 |
| Ren, YN; Tao, SJ; Tu, PC; Zhao, MQ; Zheng, SG | 1 |
| Fang, Q; Gao, G; Song, M; Wang, Q; Zhou, Z; Zhu, Y | 1 |
| Cetera, P; D'Auria, M; Mecca, M; Todaro, L | 1 |
| Chu, C; Fu, S; Jia, M; Liu, X; Liu, Z; Pan, J; Wang, Q; Zhao, Y | 1 |
| Baluchnejadmojarad, T; Khajevand-Khazaei, MR; Mirahmadi, SM; Nourabadi, D; Roghani, M; Rousta, AM; Shahmohammadi, A | 1 |
| Liu, F; Liu, J; Liu, Z; Ma, D; Xu, C; Zhang, H | 1 |
| Hamatani, Y; Hoshino, K; Kugo, H; Matsumura, S; Miyamoto, C; Moriyama, T; Sawaragi, A; Yoshioka, Y; Zaima, N | 1 |
| Di, B; Gu, XF; Li, K; Yang, DS | 1 |
| Cheng, ZY; Huang, XX; Song, SJ; Wang, J; Wang, YX; Yan, ZY; Zhou, L | 1 |
| Hirai, J; Inoue, YH; Le, TD; Nakahara, Y; Nakai, M; Okumura, K; Ono, Y; Sato, Y; Shibata, H; Takemoto, D; Tomimori, N; Ueda, M | 1 |
| Argyropoulou, A; Halabalaki, M; Mikropoulou, EV; Mitakou, S; Petrakis, EA; Skaltsounis, LA | 1 |
| Abe-Kanoh, N; Kawai, Y; Kunimoto, Y; Ohnishi, K; Ono, Y; Shibata, H; Takemoto, D | 1 |
| Ghotbzadeh Kermani, S; Gianinetti, A; Sabzalian, MR; Saeidi, G | 1 |
| Iwamoto, K; Makino, S; Matsumura, S; Moriyama, T; Yamamoto, A; Yoshioka, Y; Zaima, N | 1 |
| Dai, Q; Li, J; Li, Y; Wang, M | 1 |
| Farbood, Y; Ghaderi, S; Khorsandi, L; Khoshnam, SE; Rashno, M; Sarkaki, A | 1 |
| Azuma, T; Furukawa, A; Hori, K; Horikawa, M; Kabe, Y; Koyama, T; Mori, S; Murata, J; Okazawa, A; Ono, E; Satake, H; Suematsu, M; Tera, M; Watanabe, T | 1 |
| Haghighian, HK; Helli, B; Jalali, MT; Mowla, K; Shahi, MM | 1 |
| Ma, ZP; Yang, Y; Yang, YF; Zhang, ZF | 1 |
| Li, K; Lv, C | 1 |
| Bai, X; Cai, P; Cao, L; Gou, X; Huang, M; Jin, J; Xu, C; Zhao, Z | 1 |
| Chang, QX; Chiang, HM; Chien, TY; Hou, CW; Lin, CY; Lin, TY; Wen, KC; Wu, PY | 1 |
| Chen, Y; Ding, Y; Jiang, X; Kang, P; Li, T; Tian, J; Yi, Y; Zhang, L; Zhang, T; Zhang, Y | 1 |
| Horikawa, M; Kato, M; Murata, J; Nakayama, T; Ogata, N; Oikawa, D; Ono, E; Shiraishi, A; Takahashi, S; Toyonaga, H; Waki, T; Yamaguchi, MA | 1 |
| Dai, X; Hui, Y; Jia, M; Liu, X; Liu, Z; Pan, J; Wang, Q; Yan, S; Yu, H; Zhao, Y | 1 |
| Liu, Y; Xia, Z; Yi, T | 1 |
| Chen, Y; Huang, H; Li, H; Liu, B; Lu, C; Qi, W; Yang, Z; Zhang, L; Zhang, W | 1 |
| Akazawa, S; Funaki, A; Kominami, M; Morita, S; Okumura, H; Rogi, T; Shibata, H; Shibata, S; Tateishi, N; Tomimori, N; Yamazaki, I | 1 |
| Al Salam, S; Al Suleimani, Y; Al Tobi, M; Al Za'abi, M; Ali, BH; Ashique, M; Manoj, P; Nemmar, A; Sudhadevi, M | 1 |
| Chen, X; Deng, Y; Wang, W; Ye, S | 1 |
| Dongya, C; Hong, L; Jing, W; Mengxi, W; Mo, L; Renjie, Z | 1 |
| Che, D; Gao, J; He, H; Hou, Y; Hu, T; Wang, C; Wang, X; Wei, D | 1 |
| El Gaafary, M; Jin, L; Schmiech, M; Simmet, T; Syrovets, T; Zhang, X | 1 |
| Han, EH; Jeong, HG; Jin, SW; Kim, JY; Lee, GH; Park, JS; Pham, TH; Thai, TN | 1 |
| Dai, W; Sun, Y; Zhong, G | 1 |
| Chen, J; Chen, Y; Lin, H; Lin, M; Zheng, Y | 1 |
| Choung, SY; Hong, BN; Jeong, SY; Kang, TH; Kim, EY; Kim, YH; Nam, YH; Rodriguez, I | 1 |
| Aikawa, K; Kamijo, S; Ohmori, S; Watanabe, H; Yamaori, S | 1 |
| Gong, Z; Li, Y; Liu, Y; Wu, Q; Wu, Y; Xia, Z | 1 |
| Chu, IH; Hung, WC; Lee, WJ; Su, NW; Tsai, HY | 1 |
| Chen, JM; Chen, PY; Hsieh, MC; Lin, CC; Lin, JT | 1 |
| Amano, A; Ishigami, A; Kishimoto, Y; Ono, Y; Rogi, T; Sato, A; Shibata, H; Shimoyoshi, S; Takemoto, D | 1 |
| Feng, L; Li, S; Liu, Q; Qiao, Y; Sui, Y; Zhao, Y | 1 |
| Dai, HH; Li, XD; Wang, DY; Wang, XD; Wei, AC | 1 |
| Fujii, M; Sakaki, T; Yasuda, K | 1 |
| Kao, ZH; Kuo, PC; Lee, SW; Wu, SN | 1 |
| Kongtawelert, P; Phitak, T; Pothacharoen, P; Shwe, TH; Wudtiwai, B | 1 |
| Dalibalta, S; Majdalawieh, AF; Yousef, SM | 1 |
| Cao, J; Chen, J; Feng, C; Guo, W; He, X; Li, L; Luo, Y; Meng, R; Wang, G; Wang, T; Wu, Y; Xie, L; Yun, S | 1 |
| Kodchakorn, K; Kongtawelert, P; Poovorawan, Y; Suwannakarn, K | 1 |
| Bi, K; Li, H; Li, Q; Lin, S; Liu, R; Liu, Z; Wang, T; Xu, H | 1 |
| Gao, M; Li, ZL; Liu, JJ; Xiao, XF; Yang, BC; Yang, MS | 1 |
| Harada, E; Hideshima, K; Horikawa, M; Murata, J; Ono, E; Shiraishi, A; Toyonaga, H; Yamamoto, MP | 1 |
| Cho, HY; Jang, JH; Jeong, SH; Lee, YB | 1 |
| Bai, J; Han, Q; Li, J; Li, L; Sun, L; Wang, Y; Wu, L; Yang, Z; Ye, H | 1 |
| Chang, WT; Wu, SN | 1 |
| Bai, G; Chen, C; Li, S; Li, W; Shi, X; Zhou, T | 1 |
| Farbood, Y; Ghaderi, S; Khorsandi, L; Khoshnam, SE; Nesari, A; Rashidi, K; Rashno, M; Sarkaki, A | 1 |
| An, Q; Chen, S; Fu, BD; Li, JH; Shen, HQ; Yi, PF; Yu, JL; Zhang, CL; Zhou, XF | 1 |
| Huang, Y; Qiao, J; Wang, X; Zhao, Y; Zou, C | 1 |
| Abu-Yousef, IA; Majdalawieh, AF; Nasrallah, GK; Yousef, SM | 1 |
| Kong, L; Lei, H; Liu, P; Wang, M; Xu, N | 1 |
| Andargie, M; Karlovsky, P; Möller, E; Rathgeb, A; Vinas, M | 1 |
| Chen, M; Dong, ZY; Lan, XZ; Liao, ZH; Lu, HQ; Meng, FC; Wang, GW; Wei, L; Zeng, QH | 1 |
| Chen, R; Huang, C; Liu, N; Sun, W; Xu, RA | 1 |
| Hla Shwe, T; Kongtawelert, P; Phimphilai, M; Phitak, T; Pothacharoen, P; Udomruk, S; Wudtiwai, B | 1 |
| Abbaszadeh, H; Mottaghi, S | 1 |
| Ampasala, DR; Anju, VT; Busi, S; Dyavaiah, M; Kumar, S; Kumavath, R; Ranganathan, S; Suchiang, K | 1 |
| Cai, B; Gu, L; Mao, W; Wen, L; Xu, L | 1 |
| He, H; Li, F; Ling, X; Yang, T; Zhang, L | 1 |
| Jia, Z; Liu, H; Meng, Z; Sui, Y; Wang, Z; Zhang, J; Zhang, L; Zheng, Z | 1 |
| AbouZid, SF; Ahmed, OM; Ali, TM; Almoiliqy, M; An, S; Anggraeni, AT; Bailón-García, E; Bueno-López, A; Buyze, J; Chen, DQ; Chen, X; Davó-Quiñonero, A; De Weggheleire, A; Ding, Z; El-Kalaawy, AM; Elesawy, BH; Francque, S; Gao, F; Guo, Y; Juan-Juan, J; Li, S; Li, Y; Lin, Y; Liu, X; Liu, Z; Lozano-Castelló, D; Lu, X; Lynen, L; Meng, Q; Peng, J; Ran, Y; Razali, MH; Rodríguez, SL; Shen, MJ; Soedarsono, S; Soeprijanto, B; Su, W; Sun, P; Tang, AL; Thai, S; Tian, G; Topîrceanu, A; van Griensven, J; Wang, H; Wang, Y; Wen, J; Xi, J; Xiong, MC; Yang, S; Yang, X; Yassin, NYS; Ye, L; Yusoff, M; Zhang, GQ; Zhang, Y | 1 |
| Hayes, AW; Karimi, G; Tabrizi, FB; Yarmohammadi, F | 1 |
| Chen, FG; Deng, JL; Guo, ZH; Li, RQ; Li, X; Ma, YX; Pei, HT; Ren, JY; Sun, YT; Yin, BW; Zhang, F; Zhang, ZA; Zhu, SQ | 1 |
| Srisongkram, T; Weerapreeyakul, N | 1 |
| Feng, L; Li, G; Li, Y; Lin, S; Lo, JHT; Lu, X; Tortorella, MD; Wang, H; Wang, Y; Yang, Z; Zhang, X | 1 |
| Abe, T; Katayama, T; Kikuchi, K; Nakayama, T; Oikawa, D; Takahashi, S; Waki, T; Yamashita, S | 1 |
| Li, L; Xiu, F; Zhang, J | 1 |
| Hong, TW; Okuda, M; Sasaki, T; Sato, R; Shimizu, M; Takahashi, Y; Watanabe, Y; Yamauchi, Y | 1 |
| An, J; Guo, Z; Ma, Y; Ren, J; Sun, Y; Yin, B; Zhang, Z; Zhu, S | 1 |
| Chang, M; Karrar, E; Liu, R; Shi, L; Wang, X | 1 |
| Bai, Q; Jiang, J; Li, L; Liu, H; Piao, H; Piao, Q; Piao, Y; Song, Y; Wang, Z; Yan, G; Zhou, X | 1 |
| Ghaderi, S; Khoshnam, SE; Rashno, M; Sarkaki, A | 1 |
| Beirak Olia, MD; Emami, SA; Ghaderi, MA; Javadi, B | 1 |
| Abbasi, MM; Mahmoodi, MR | 1 |
| Bai, S; Feng, L; Li, G; Li, Y; Lin, S; Lu, X; Tortorella, MD; Wang, H; Wang, M; Wang, Y; Yang, Z; Zhang, X | 1 |
| Iinuma, KM; Jinno, S; Maeda, S; Nishida, H; Soya, M; Yamada, J | 1 |
| Kaewmool, C; Kongtawelert, P; Phimphilai, M; Phitak, T; Pothacharoen, P; Shwe, TH | 1 |
| Cui, Q; Guo, Z; Li, X; Ma, Y; Pei, H; Ren, J; Song, J; Yin, B; Zhu, S | 1 |
| Chen, Y; Huang, Y; Jiang, M; Li, J; Li, L; Liu, Z; Tang, Y; Zhou, L | 1 |
| Ahmed, RA; Alam, MF; Ali Thubab, HM; Ali Zaeri, AM; Alshahrani, S; Anwer, T; Jali, AM; Moni, SS; Nomier, Y; Qadri, M | 1 |
| Huo, J; Yan, Y; Yang, Y; Yu, J | 1 |
| Araki, C; Hara, E; Izumo, T; Kawamoto, S; Kitagawa, Y; Nakai, M; Rogi, T; Shibata, H; Takemoto, D; Tateishi, N | 1 |
| Chanchao, C; Kim, WK; Kitipaspallop, W; Phuwapraisirisan, P; Pimtong, W | 1 |
| Lu, X; Tan, H; Wang, D; Wang, J; Wei, Q; Zhang, Y | 1 |
| Choi, CY; Han, EH; Jeong, GS; Jeong, HG; Jin, SW; Ki Lee, S; Kim, HS; Kim, ND; Lee, GH; Lee, SY; Pham, TH | 1 |
| He, B; Huang, L; Huang, WJ; Huang, XT; Liu, L; Liu, W; Luo, YY; Luo, ZQ; Sang, XX; Tang, SY; Tian, YM; Wu, B; Zeng, Q; Zhang, XH; Zhou, TT | 1 |
| Izumo, T; Kaneda, Y; Morita, S; Nakai, M; Rogi, T; Sasaki, H | 1 |
| Chuang, CH; Hsieh, CY; Huang, SK; Huang, SM; Rejano, CJF; Tayo, LL; Tsai, PW | 1 |
Reviews
16 review(s) available for sesamin and lignans
| Article | Year |
|---|---|
Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions.
Topics: Animals; Benzofurans; Dioxoles; Feeding Behavior; Furans; Host-Parasite Interactions; Insecta; Larva; Lignans; Malpighian Tubules; Masoprocol; Molting; Podophyllotoxin; Rhodnius; Trypanosoma cruzi | 2004 |
How is sesamin metabolised in the human liver to show its biological effects?
Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronosyltransferase; Humans; Lignans; Liver; Oxidation-Reduction; Sesamum; Tissue Distribution | 2012 |
The relationship of antioxidant components and antioxidant activity of sesame seed oil.
Topics: Antioxidants; Benzodioxoles; Diet; Dioxoles; gamma-Tocopherol; Humans; Lignans; Phenols; Seeds; Sesame Oil; Sesamum | 2015 |
Pharmacological effect of functional foods with a hypotensive action.
Topics: Acetic Acid; Animals; Antihypertensive Agents; Catechin; Dioxoles; Diterpenes, Kaurane; Docosahexaenoic Acids; Eicosapentaenoic Acid; Functional Food; gamma-Aminobutyric Acid; Garlic; Glucosides; Humans; Hypertension; Lignans; Onions | 2015 |
Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review.
Topics: Antineoplastic Agents; Catechin; Coumaric Acids; Dietary Supplements; Dioxoles; Drug Synergism; Drug Therapy, Combination; Humans; Lignans; Neoplasms; Resveratrol; Stilbenes; Tocotrienols | 2016 |
Acanthopanax senticosus: Photochemistry and Anticancer Potential.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Coumarins; Dioxoles; Dose-Response Relationship, Drug; Eleutherococcus; Glucosides; Humans; Immunologic Factors; Lignans; Medicine, Chinese Traditional; Mice; Phenylpropionates; Phytotherapy; Rats | 2016 |
A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
Topics: Animals; Antineoplastic Agents; Dioxoles; Humans; Lignans; Neoplasms; Seeds; Sesamum | 2017 |
Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: A comprehensive review.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Dioxoles; Fatty Acids; Humans; Lignans; Lipid Metabolism; Macrophages | 2020 |
Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions.
Topics: Anti-Inflammatory Agents; Dioxoles; Humans; Immunity; Inflammation; Lignans; Sesamum | 2022 |
Lignans of Sesame (
Topics: Benzodioxoles; Dioxoles; Furans; Lignans; Oxidation-Reduction; Phenols; Seeds; Sesamum | 2021 |
A comprehensive mechanistic insight into the dietary and estrogenic lignans, arctigenin and sesamin as potential anticarcinogenic and anticancer agents. Current status, challenges, and future perspectives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Dioxoles; Furans; Humans; Lignans; Neoplasms | 2022 |
Sesamin and sesamolin rescues Caenorhabditis elegans from Pseudomonas aeruginosa infection through the attenuation of quorum sensing regulated virulence factors.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Caenorhabditis elegans; Dioxoles; Humans; Lignans; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Virulence Factors | 2021 |
The modulation of SIRT1 and SIRT3 by natural compounds as a therapeutic target in doxorubicin-induced cardiotoxicity: A review.
Topics: Animals; Berberine; Cardiotoxicity; Dioxoles; Doxorubicin; Heart Diseases; Humans; Lignans; Myocardium; Sirtuin 1; Sirtuin 3 | 2022 |
The Effects of Sesamin Supplementation on Obesity, Blood Pressure, and Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Blood Pressure; Cholesterol, LDL; Dietary Supplements; Dioxoles; Humans; Lignans; Lipids; Obesity; Randomized Controlled Trials as Topic | 2022 |
The Role of Sesamin in Targeting Neurodegenerative Disorders: A Systematic Review.
Topics: Alzheimer Disease; Dioxoles; Humans; Lignans; Parkinson Disease | 2023 |
Therapeutic Effectiveness of Sesame Preparations and its Bioactive Ingredients in Management of Cardiometabolic Syndrome in Diabetes Mellitus: A Systematic Review.
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Lignans; Metabolic Syndrome; Seeds; Sesame Oil; Sesamum | 2023 |
Trials
8 trial(s) available for sesamin and lignans
| Article | Year |
|---|---|
Hypocholesterolemic effect of sesame lignan in humans.
Topics: Anticholesteremic Agents; Cholesterol; Dioxoles; Humans; Lignans; Lipids; Male | 1996 |
Antihypertensive effects of sesamin in humans.
Topics: Antihypertensive Agents; Blood Pressure; Dioxoles; Double-Blind Method; Female; Humans; Hypertension; Lignans; Male; Middle Aged; Phytotherapy; Plant Extracts; Seeds; Sesamum | 2009 |
Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studies.
Topics: Antihypertensive Agents; Dietary Supplements; Dioxoles; Female; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Lignans; Male; Microsomes, Liver; Middle Aged; Plant Extracts; Probability; Reference Values; Treatment Outcome | 2009 |
Improvement of liver function in humans using a mixture of schisandra fruit extract and sesamin.
Topics: Adult; Aged; Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Bilirubin; Dioxoles; Female; Fruit; Glutathione Peroxidase; Glutathione Reductase; Humans; Lignans; Liver; Liver Function Tests; Male; Middle Aged; Oxidative Stress; Plant Extracts; Schisandra; Superoxides; Thiobarbituric Acid Reactive Substances; Young Adult | 2013 |
Pharmacokinetics and safety of the sesame lignans, sesamin and episesamin, in healthy subjects.
Topics: Adult; Dioxoles; Female; Humans; Lignans; Male; Middle Aged; Sesamum; Young Adult | 2013 |
Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study.
Topics: Adult; Antioxidants; Biomarkers; Cross-Over Studies; Dietary Supplements; Dioxoles; Double-Blind Method; Female; Health Status; Humans; Japan; Lignans; Lipid Peroxidation; Male; Mental Fatigue; Mental Health; Middle Aged; Neuropsychological Tests; Oxidative Stress; Phosphatidylcholines; Recovery of Function; Surveys and Questionnaires; Time Factors; Treatment Outcome; Xanthophylls | 2018 |
Effects of Composite Supplement Containing Astaxanthin and Sesamin on Cognitive Functions in People with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Aged; Cognitive Dysfunction; Dietary Supplements; Dioxoles; Double-Blind Method; Female; Humans; Lignans; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Treatment Outcome; Xanthophylls | 2018 |
A randomized, triple-blind, placebo-controlled clinical trial, evaluating the sesamin supplement effects on proteolytic enzymes, inflammatory markers, and clinical indices in women with rheumatoid arthritis.
Topics: Antioxidants; Arthritis, Rheumatoid; Biomarkers; Dietary Supplements; Dioxoles; Double-Blind Method; Female; Humans; Inflammation; Lignans; Middle Aged; Peptide Hydrolases | 2019 |
Other Studies
372 other study(ies) available for sesamin and lignans
| Article | Year |
|---|---|
Effects of sesamin and curcumin on delta 5-desaturation and chain elongation of polyunsaturated fatty acid metabolism in primary cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Curcumin; Dioxoles; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Lignans; Liver; Male; Rats; Rats, Wistar | 1992 |
Sesame seed lignans and gamma-tocopherol act synergistically to produce vitamin E activity in rats.
Topics: Animals; Diet; Dioxoles; Drug Synergism; Furans; Hemolysis; Lignans; Liver; Male; Peroxides; Pyruvate Kinase; Rats; Rats, Wistar; Vitamin E | 1992 |
Inhibition of cholesterol absorption and synthesis in rats by sesamin.
Topics: Absorption; Alanine Transaminase; Animals; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Dioxoles; Feces; Lignans; Lymph; Male; Microsomes, Liver; Organ Size; Rats; Rats, Inbred Strains; Sesame Oil; Taurocholic Acid | 1991 |
Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis.
Topics: Animals; Delta-5 Fatty Acid Desaturase; Dioxoles; Fatty Acid Desaturases; Fatty Acids, Unsaturated; In Vitro Techniques; Kinetics; Lignans; Male; Microsomes, Liver; Mucorales; Rats; Rats, Inbred Strains; Sesame Oil | 1991 |
[Studies on the chemical constituents of Zanthoxylum planispinum Sieb. et Zucc].
Topics: Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Dioxoles; Drugs, Chinese Herbal; Lignans; Oleanolic Acid; Triterpenes | 1988 |
Is sesamol present in sesame oil?
Topics: Adult; Benzodioxoles; Cheilitis; Chromatography, High Pressure Liquid; Dermatitis, Contact; Dioxoles; Female; Humans; Lignans; Patch Tests; Phenols; Plant Oils; Sesame Oil | 1987 |
Effects of sesamin on the fatty acid composition of the liver of rats fed N-6 and N-3 fatty acid-rich diet.
Topics: alpha-Linolenic Acid; Animals; Diet; Dioxoles; Fatty Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Lignans; Liver; Male; Rats; Rats, Wistar; Sesame Oil | 1995 |
Antihypertensive effect of sesamin. I. Protection against deoxycorticosterone acetate-salt-induced hypertension and cardiovascular hypertrophy.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Desoxycorticosterone; Diet; Dioxoles; Hypertension; Hypertrophy; Lignans; Male; Nephrectomy; Rats; Rats, Sprague-Dawley | 1995 |
Sesamin (a compound from sesame oil) increases tocopherol levels in rats fed ad libitum.
Topics: Animals; Diet; Dioxoles; Lignans; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Regression Analysis; Sesame Oil; Vitamin E | 1995 |
Lack of influence of low blood cholesterol levels on pancreatic carcinogenesis after initiation with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Topics: Animals; Carcinogens; Cholesterol; Cholestyramine Resin; Cricetinae; Dioxoles; Female; Lignans; Lipid Peroxides; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms | 1994 |
Protective effects of sesamin against liver damage caused by alcohol or carbon tetrachloride in rodents.
Topics: Administration, Inhalation; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dioxoles; Ethanol; Fatty Acid Desaturases; Fatty Acids; Lignans; Lipid Metabolism; Liver Diseases; Male; Mice; Microsomes, Liver; Rats; Rats, Wistar | 1993 |
Effects of sesamin on serum lipoprotein metabolism in normocholesterolemic and hypercholesterolemic stroke-prone SHR.
Topics: Animals; Dioxoles; Hypercholesterolemia; Lignans; Lipase; Lipoprotein Lipase; Lipoproteins; Male; Rats; Rats, Inbred SHR | 1993 |
Inhibitory effects of alkyl gallate and its derivatives on fatty acid desaturation.
Topics: Animals; Antioxidants; Delta-5 Fatty Acid Desaturase; Dioxoles; Enzyme Inhibitors; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Fungi; Kinetics; Lignans; Male; Microsomes, Liver; Propyl Gallate; Rats; Rats, Wistar; Sesame Oil | 1996 |
Sesame seed and its lignans produce marked enhancement of vitamin E activity in rats fed a low alpha-tocopherol diet.
Topics: Animals; Antioxidants; Diet; Dioxoles; Furans; Kidney; Lignans; Liver; Male; Rats; Rats, Wistar; Vitamin E | 1995 |
Effects of sesamin and alpha-tocopherol, individually or in combination, on the polyunsaturated fatty acid metabolism, chemical mediator production, and immunoglobulin levels in Sprague-Dawley rats.
Topics: Animals; Anticholesteremic Agents; Body Weight; Dioxoles; Drug Interactions; Eicosanoids; Fatty Acids, Unsaturated; Histamine; Immunoglobulins; Lignans; Lipid Metabolism; Liver; Lymph Nodes; Lymphocytes; Male; Mesentery; Organ Size; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Spleen; Vitamin E | 1995 |
Interaction of sesamin and eicosapentaenoic acid against delta 5 desaturation and n-6/n-3 ratio of essential fatty acids in rat.
Topics: Animals; Anticholesteremic Agents; Body Weight; Brain; Dioxoles; Drug Interactions; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Lignans; Lipids; Liver; Male; Organ Size; Phosphatidylcholines; Rats; Rats, Wistar; Tissue Distribution | 1995 |
alpha-Tocopherol enhances the hypocholesterolemic action of sesamin in rats.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Dioxoles; Drug Interactions; Lignans; Liver; Male; Organ Size; Rats; Rats, Wistar; Vitamin E; Weight Gain | 1995 |
Antihypertensive effect of sesamin. II. Protection against two-kidney, one-clip renal hypertension and cardiovascular hypertrophy.
Topics: Animals; Antihypertensive Agents; Cardiomegaly; Dioxoles; Hypertension, Renovascular; Lignans; Male; Rats; Rats, Sprague-Dawley; Sesame Oil | 1995 |
Effect of sesamin on the composition of eicosapentaenoic acid in liver and on its lymphatic absorption in rats.
Topics: Animals; Anticholesteremic Agents; Dioxoles; Eicosapentaenoic Acid; Fatty Acids; Lignans; Liver; Lymphatic System; Male; Rats; Rats, Wistar | 1996 |
Sesame lignans modulate cholesterol metabolism in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins; Blood Pressure; Cerebrovascular Disorders; Cholesterol; Dioxoles; Hypercholesterolemia; Lignans; Lipid Metabolism; Lipids; Male; Rats; Rats, Inbred SHR; Sterol O-Acyltransferase | 1995 |
Effects of dietary sesaminol and sesamin on eicosanoid production and immunoglobulin level in rats given ethanol.
Topics: Analysis of Variance; Animals; Diet; Dinoprostone; Dioxoles; Ethanol; Furans; Immunoglobulins; Leukotriene B4; Lignans; Male; Rats; Rats, Wistar; Sesame Oil; Spleen | 1997 |
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Dioxoles; Female; Furans; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Phenols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented
Topics: Animals; Dietary Supplements; Dinoprostone; Dioxoles; Eicosanoids; Fatty Acids; Female; Interleukins; Lignans; Liver; Membranes; Mice; Mice, Inbred BALB C; Quillaja Saponins; Saponins; Sesame Oil; Shock, Septic; Survival Analysis; Thromboxane B2 | 1997 |
Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice.
Topics: alpha-Linolenic Acid; Animals; Anticholesteremic Agents; Delta-5 Fatty Acid Desaturase; Dietary Fats, Unsaturated; Dinoprostone; Dioxoles; Dose-Response Relationship, Drug; Fatty Acid Desaturases; Fatty Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Interleukin-10; Interleukin-6; Lignans; Lipopolysaccharides; Membrane Lipids; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 1998 |
Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Cerebrovascular Disorders; Diet; Dioxoles; Heart Rate; Hypertension; Kidney; Kidney Diseases; Lignans; Male; Myocardium; Rats; Rats, Inbred SHR | 1998 |
The metabolism and n-6/n-3 ratio of essential fatty acids in rats: effect of dietary arachidonic acid and a mixture of sesame lignans (sesamin and episesamin).
Topics: Animals; Arachidonic Acid; Dietary Fats, Unsaturated; Dioxoles; Fatty Acids, Essential; Fatty Acids, Unsaturated; Ketone Bodies; Lignans; Liver; Male; Rats; Rats, Wistar; Sesame Oil; Triglycerides | 1998 |
Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats.
Topics: alpha-Linolenic Acid; Animals; Anticholesteremic Agents; Dietary Fats; Dioxoles; gamma-Linolenic Acid; Immunoglobulins; Lignans; Linoleic Acid; Lipids; Male; Plant Oils; Rats; Rats, Sprague-Dawley; Safflower Oil | 1998 |
Reciprocal effects of dietary sesamin on ketogenesis and triacylglycerol secretion by the rat liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Antioxidants; Cholesterol; Diet; Dioxoles; Ketone Bodies; Kinetics; Lignans; Liver; Male; Oleic Acid; Organ Size; Rats; Rats, Wistar; Triglycerides | 1998 |
The metabolism and distribution of sesame lignans (sesamin and episesamin) in rats.
Topics: Animals; Brain; Dioxoles; Kidney; Lignans; Liver; Lung; Lymph; Male; Myocardium; Rats; Rats, Wistar; Tissue Distribution | 1999 |
Dietary defatted sesame flour decreases susceptibility to oxidative stress in hypercholesterolemic rabbits.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Antioxidants; Body Weight; Cholesterol, Dietary; Cholesterol, LDL; Chromatography, High Pressure Liquid; Dietary Fats; Dioxoles; Flour; Furans; Hypercholesterolemia; Lignans; Lipid Peroxidation; Liver; Male; Organ Size; Oxidative Stress; Rabbits; Vitamin E | 1999 |
Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Cholesterol; Dioxoles; DNA Primers; DNA Probes; Fatty Acids, Nonesterified; Gene Expression Regulation, Enzymologic; Lignans; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Palmitoyl Coenzyme A; Peroxisomes; Phospholipids; Rats; Rats, Sprague-Dawley; Triglycerides | 1999 |
Effect of dietary sesamin on metabolic fate of an exogenous linolelaidic acid in perfused rat liver.
Topics: Animals; Diet; Dioxoles; Fatty Acids; Hypolipidemic Agents; Ketone Bodies; Lignans; Linoleic Acid; Lipid Metabolism; Liver; Male; Rats; Rats, Wistar; Triglycerides | 1999 |
Sesamin and alpha-tocopherol synergistically suppress lipid-peroxide in rats fed a high docosahexaenoic acid diet.
Topics: Animals; Antioxidants; Dietary Fats, Unsaturated; Dioxoles; Docosahexaenoic Acids; Drug Synergism; Hemolysis; Lignans; Lipid Peroxidation; Lipid Peroxides; Liver; Rats; Triglycerides; Vitamin E | 2000 |
Sesamin and episesamin induce apoptosis in human lymphoid leukemia Molt 4B cells.
Topics: Antineoplastic Agents; Apoptosis; Dioxoles; DNA Fragmentation; Humans; Leukemia, Lymphoid; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microscopy, Fluorescence; Sesame Oil; Tumor Cells, Cultured | 2000 |
Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats.
Topics: Animals; Butylated Hydroxytoluene; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Coumaric Acids; Curcumin; Diet; Dioxoles; Fatty Acids; Lignans; Liver; Lung; Male; Phenols; Rats; Rats, Sprague-Dawley; Vitamin E | 2000 |
Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor alpha in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Body Weight; Dietary Fats; Dietary Supplements; Dinoprostone; Dioxoles; Emulsions; Fatty Acids; Lignans; Lipopolysaccharides; Liver; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2000 |
Effects of sesamin on altered vascular reactivity in aortic rings of deoxycorticosterone acetate-salt-induced hypertensive rat.
Topics: Animals; Antihypertensive Agents; Aorta; Body Weight; Desoxycorticosterone; Diet; Dioxoles; Hypertension; In Vitro Techniques; Lignans; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sodium Chloride; Vasoconstriction | 2000 |
Cytochrome P4503A-dependent metabolism of tocopherols and inhibition by sesamin.
Topics: Antioxidants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Inhibitors; Humans; Isoenzymes; Ketoconazole; Lignans; Liver; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Tumor Cells, Cultured; Vitamin E | 2000 |
Constituents and cytotoxicity of Zanthoxylum rhesta stem bark.
Topics: Animals; Artemia; Coumarins; Dioxoles; Humans; Lignans; Plant Extracts; Plant Stems; Plants, Medicinal; Pyrans; Quinolones | 2000 |
Sesamin inhibits lysophosphatidylcholine acyltransferase in Mortierella alpina.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Antioxidants; Dioxoles; Intracellular Membranes; Kinetics; Lignans; Microsomes; Mucorales; Sesame Oil | 2000 |
Sesamin a potent antifeedant principle from Piper mullesua.
Topics: Animals; Dioxoles; Growth Inhibitors; Insecticides; Larva; Lepidoptera; Lignans | 2001 |
Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver.
Topics: Animals; Antioxidants; Dioxoles; Fatty Acids; Lignans; Lipids; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; Seeds | 2001 |
Effect of sesamin on mitochondrial and peroxisomal beta-oxidation of arachidonic and eicosapentaenoic acids in rat liver.
Topics: Animals; Arachidonic Acid; Body Weight; Chromatography, Thin Layer; Dioxoles; Eicosapentaenoic Acid; Feeding Behavior; Lignans; Liver; Male; Mitochondria, Liver; Organ Size; Oxidation-Reduction; Peroxisomes; Rats; Rats, Wistar | 2001 |
Effects of some lignans and neolignans on the development and excretion of Rhodnius prolixus.
Topics: Animals; Benzofurans; Dioxoles; Feeding Behavior; Furans; Larva; Lauraceae; Lignans; Masoprocol; Plants, Medicinal; Podophyllotoxin; Rhodnius | 2000 |
Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues.
Topics: Dioxoles; Furans; Lignans; Magnoliopsida; Oxygen; Seeds; Sesame Oil; Stereoisomerism | 1997 |
C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin.
Topics: Anti-Allergic Agents; Anticholesteremic Agents; Antihypertensive Agents; Antineoplastic Agents; Antioxidants; Dioxoles; Drugs, Chinese Herbal; Furans; Lignans; Lignin; Platelet Aggregation Inhibitors | 2001 |
Effects of dietary sesame seeds on plasma tocopherol levels.
Topics: Adult; Aging; Antioxidants; Bread; Chromatography, High Pressure Liquid; Dioxoles; Female; Food Analysis; gamma-Tocopherol; Humans; Lignans; Male; Middle Aged; Nuts; Seeds; Sesame Oil; Soybean Oil; Tocopherols | 2001 |
Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1.
Topics: Acetyl-CoA Carboxylase; Animals; ATP Citrate (pro-S)-Lyase; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cholesterol; Dioxoles; DNA-Binding Proteins; Down-Regulation; Fatty Acid Synthases; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucosephosphate Dehydrogenase; Lignans; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, LDL; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 2001 |
Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Pressure; Blood Vessels; Body Weight; Cerebrovascular Circulation; Cerebrovascular Disorders; Deoxyguanosine; Dioxoles; Disease Susceptibility; Drug Combinations; Genetic Predisposition to Disease; Hypertension; Lignans; Male; Microcirculation; Rats; Rats, Inbred SHR; Stroke; Thrombosis; Vasomotor System; Vitamin E | 2001 |
Dietary manipulations of body fat-reducing potential of conjugated linoleic acid in rats.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Diet, Reducing; Dietary Fats, Unsaturated; Dietary Proteins; Dioxoles; Leptin; Lignans; Linoleic Acids; Lipids; Male; Organ Size; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2001 |
Short and stereoselective total synthesis of furano lignans (+/-)-dihydrosesamin, (+/-)-lariciresinol dimethyl ether, (+/-)-acuminatin methyl ether, (+/-)-sanshodiol methyl ether, (+/-)-lariciresinol, (+/-)-acuminatin, and (+/-)-lariciresinol monomethyl e
Topics: Alkylation; Catalysis; Chemistry, Organic; Cyclization; Dioxoles; Epoxy Compounds; Ethers, Cyclic; Flavonoids; Furans; Glycosides; Lignans; Lignin; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism | 2002 |
Antihypertensive effect of sesamin. IV. Inhibition of vascular superoxide production by sesamin.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Dioxoles; Hypertension; Lignans; Male; Rats; Rats, Sprague-Dawley; Superoxides | 2002 |
Determination of L-sesamin and L-asarinin in Zanthoxylum(Roxb.) DC. by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Dioxoles; Drugs, Chinese Herbal; Lignans; Plants, Medicinal; Zanthoxylum | 2002 |
[Studies on the chemical constituents of the herba of Cuscuta chinensis].
Topics: Chemical Fractionation; Cuscuta; Dioxoles; Drugs, Chinese Herbal; Furans; Lignans; Sitosterols; Spectrum Analysis | 2001 |
Novel antioxidative metabolites in rat liver with ingested sesamin.
Topics: Animals; Antioxidants; Bile; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dioxoles; Free Radical Scavengers; Hydroxyl Radical; Lignans; Lipid Peroxidation; Liver; Magnetic Resonance Spectroscopy; Male; Picrates; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2003 |
Combined effects of dietary conjugated linoleic acid and sesamin triacylglycerol and ketone body production in rat liver.
Topics: Animals; Anticholesteremic Agents; Body Composition; Diet; Dioxoles; Ketone Bodies; Lignans; Linoleic Acid; Lipid Metabolism; Liver; Male; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides; Weight Gain | 2002 |
Protective effect of sesamin administration on exercise-induced lipid peroxidation.
Topics: Animals; Antioxidants; Dioxoles; Enzyme Activation; Glutathione Peroxidase; Humans; Lignans; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Physical Conditioning, Animal | 2003 |
Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells.
Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cytoprotection; Dioxoles; Dose-Response Relationship, Drug; Lignans; Neurons; PC12 Cells; Rats; Rats, Sprague-Dawley | 2003 |
[Synthesis of DL-asarinin and DL-sesamin].
Topics: Dioxoles; Heterocyclic Compounds; Lignans | 1957 |
Dietary (+)-catechin and BHT markedly increase alpha-tocopherol concentrations in rats by a tocopherol-omega-hydroxylase-independent mechanism.
Topics: alpha-Tocopherol; Animals; Antioxidants; Body Weight; Butylated Hydroxytoluene; Catechin; Cells, Cultured; Cholesterol; Diet; Dioxoles; Enzyme Inhibitors; gamma-Tocopherol; Hepatocytes; Lignans; Lipids; Liver; Lung; Male; Mixed Function Oxygenases; Organ Size; Rats; Rats, Sprague-Dawley | 2003 |
Dietary sesame lignans decrease lipid peroxidation in rats fed docosahexaenoic acid.
Topics: alpha-Tocopherol; Animals; Antioxidants; Brain; Dioxoles; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Furans; Hemolysis; Lignans; Lipid Peroxidation; Liver; Male; Random Allocation; Rats; Rats, Wistar; Sesamum; Thiobarbituric Acid Reactive Substances | 2003 |
Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cyclic N-Oxides; Desoxycorticosterone; Dioxoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Endothelium, Vascular; Hypertension; Hypertension, Renovascular; Lignans; Male; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasodilation | 2003 |
Effect of dietary fat level and sesamin on the polyunsaturated fatty acid metabolism in rats.
Topics: 8,11,14-Eicosatrienoic Acid; Acyl-CoA Dehydrogenase; alpha-Linolenic Acid; Animals; Arachidonic Acid; Carnitine Acyltransferases; Dietary Fats; Dioxoles; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Lignans; Linoleic Acid; Liver; Male; Mitochondria, Liver; Plant Oils; Rapeseed Oil; Rats; Rats, Wistar; Soybean Oil | 2003 |
Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system.
Topics: Antioxidants; Benzodioxoles; Biphenyl Compounds; Dioxoles; Free Radical Scavengers; Free Radicals; Furans; Kinetics; Lignans; Phenols; Picrates; Plant Extracts; Sesamum | 2004 |
Effects of sesamin and capsaicin on the mRNA expressions of delta6 and delta5 desaturases in rat primary cultured hepatocytes.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Capsaicin; Cells, Cultured; Delta-5 Fatty Acid Desaturase; Dioxoles; Fatty Acid Desaturases; Gene Expression; Hepatocytes; Lignans; Linoleic Acid; Linoleoyl-CoA Desaturase; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism.
Topics: Animals; Antioxidants; Blotting, Northern; Cricetinae; Dioxoles; Fatty Acids; Insulin; Lignans; Lipids; Liver; Male; Mesocricetus; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Species Specificity | 2004 |
Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae.
Topics: Animals; Aristolochia; Aristolochic Acids; Biological Assay; Dioxoles; Diterpenes; Furans; Insecticides; Larva; Lepidoptera; Lignans; Plant Extracts | 2004 |
Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats.
Topics: Animals; Dietary Fats, Unsaturated; Dioxoles; Enzymes; Fatty Acids; Fish Oils; Lignans; Liver; Male; Oxidation-Reduction; Palm Oil; Plant Oils; Rats; RNA, Messenger; Safflower Oil | 2004 |
Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia.
Topics: Animals; Antioxidants; Blotting, Western; Caspase 3; Caspases; Catalase; Cell Hypoxia; Cell Line; Cell Survival; Dioxoles; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Lignans; Mice; Microglia; Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected].
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Diet; Dioxoles; Glutathione Peroxidase; Iron; Lignans; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Sesame Oil; Superoxide Dismutase; Tocopherols | 2004 |
Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs: possible implications for its antihypertensive effect.
Topics: Antihypertensive Agents; Aspartic Acid Endopeptidases; Cells, Cultured; Culture Media; Cyclic GMP; Dioxoles; Endothelial Cells; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Induction; Humans; Lignans; Metalloendopeptidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osmolar Concentration; RNA, Messenger; Signal Transduction | 2004 |
Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB.
Topics: Animals; Antioxidants; Cytokines; Dioxoles; Interleukin-6; Lignans; Lipopolysaccharides; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; RNA, Messenger | 2005 |
Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study.
Topics: Administration, Oral; Alcohol Drinking; Animals; Antioxidants; Body Temperature; Dioxoles; Ethanol; Exercise; Glucuronides; Humans; Lignans; Lipid Metabolism; Lipid Peroxidation; Liver; Oligonucleotide Array Sequence Analysis; Phytotherapy; Rats; Seeds; Sesamum; Tissue Distribution | 2004 |
Antioxidative catechol lignans converted from sesamin and sesaminol triglucoside by culturing with Aspergillus.
Topics: Antioxidants; Aspergillus; Catechols; Dioxoles; Furans; Glucosides; Lignans | 2005 |
Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats.
Topics: Animals; Depressive Disorder; Dioxoles; Eleutherococcus; Lignans; Male; Parkinsonian Disorders; Plant Bark; Plant Extracts; Rats; Rats, Inbred Lew; Rotenone | 2005 |
Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Deoxyguanosine; Dioxoles; Fibrinolytic Agents; Hypertension; Intracranial Thrombosis; Lignans; Rats; Rats, Inbred SHR; Stroke; Vitamin E | 2004 |
Modulating effect of sesamin, a functional lignan in sesame seeds, on the transcription levels of lipid- and alcohol-metabolizing enzymes in rat liver: a DNA microarray study.
Topics: Alcohols; Animals; Dioxoles; Down-Regulation; Gene Expression Regulation, Enzymologic; Lignans; Lipid Metabolism; Liver; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Seeds; Sesamum; Transcription, Genetic; Up-Regulation | 2005 |
Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans.
Topics: alpha-Tocopherol; Chromans; Deuterium; Diet; Dioxoles; Food; gamma-Tocopherol; Humans; Kinetics; Lignans; Sesame Oil | 2004 |
NMR spectroscopic, mass spectroscopic, X-ray crystallographic, and theoretical studies of molecular mechanics of natural products: farformolide B and sesamin.
Topics: Biological Products; Crystallography, X-Ray; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Plants; Sesquiterpenes; Stereoisomerism; Thermodynamics | 2005 |
Dietary sesamin is converted to enterolactone in humans.
Topics: 4-Butyrolactone; Adult; Biotransformation; Diet; Dioxoles; Female; Humans; Intestinal Absorption; Kinetics; Lignans; Male; Middle Aged | 2005 |
The epimerization of sesamin and asarinin.
Topics: Crystallography, X-Ray; Dioxoles; Drugs, Chinese Herbal; Lignans; Models, Molecular; Molecular Conformation; Molecular Structure; Plants, Medicinal; Stereoisomerism | 2005 |
Sesamin ingestion regulates the transcription levels of hepatic metabolizing enzymes for alcohol and lipids in rats.
Topics: Aldehyde Dehydrogenase; Animals; Dioxoles; Ethanol; Gene Expression Regulation, Enzymologic; Lignans; Lipid Metabolism; Liver; Male; Oligonucleotide Array Sequence Analysis; Peroxisomes; Rats; Rats, Wistar; Transcription, Genetic | 2005 |
Antioxidant activity and bioactive compounds of tea seed (Camellia oleifera Abel.) oil.
Topics: Antioxidants; Camellia; Dioxoles; Hemolysis; Humans; Lignans; Lipid Peroxidation; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Plant Oils; Reactive Oxygen Species; Seeds | 2006 |
Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in rats.
Topics: Animals; Dioxoles; Docosahexaenoic Acids; Drug Synergism; Eicosapentaenoic Acid; Enzymes; Fatty Acids; Fatty Acids, Omega-3; Gene Expression Regulation, Enzymologic; Lignans; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2006 |
Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats.
Topics: Animals; Butylene Glycols; Dioxoles; Feces; Female; Fermentation; Flax; Gas Chromatography-Mass Spectrometry; Glucosides; Humans; Lignans; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Seeds; Sesamum | 2006 |
Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin.
Topics: Animals; Antihypertensive Agents; Antioxidants; Dioxoles; Hypertension; Lignans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Binding; Rats; Rats, Sprague-Dawley; Vasodilation | 2006 |
Decomposition reaction of sesamin in supercritical water.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Dioxoles; Free Radical Scavengers; Hot Temperature; Lignans; Water | 2006 |
[Effect of asarinin on the acute heart transplantation rejection and the expression of adhesion molecule].
Topics: Animals; Asarum; Dioxoles; Graft Rejection; Graft Survival; Heart Transplantation; Intercellular Adhesion Molecule-1; Lignans; Male; Myocardium; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Vascular Cell Adhesion Molecule-1 | 2006 |
Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin.
Topics: Amino Acid Sequence; Catalysis; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Gene Expression; Gene Expression Profiling; Lignans; Molecular Sequence Data; Plant Proteins; Sesamum | 2006 |
Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Diet, Atherogenic; Dioxoles; Female; Lignans; Mice; Mice, Inbred Strains; Random Allocation; Receptors, LDL; Specific Pathogen-Free Organisms; Triglycerides; Weight Gain | 2006 |
Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats.
Topics: Animals; Base Sequence; Diacylglycerol O-Acyltransferase; Dietary Fats, Unsaturated; Dioxoles; DNA Primers; Dose-Response Relationship, Drug; Fatty Acid Synthases; Fatty Acids; Glycerol-3-Phosphate O-Acyltransferase; Lignans; Lipid Metabolism; Liver; Male; Molecular Sequence Data; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2007 |
An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H(2)O(2) and UHP systems.
Topics: Animals; Antineoplastic Agents; Dioxoles; Drug Screening Assays, Antitumor; Humans; Lignans; Mice; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Rhenium; Stereoisomerism; Zanthoxylum | 2007 |
Quantitative NMR analysis of a sesamin catechol metabolite in human urine.
Topics: Adult; Catechols; Chromatography, High Pressure Liquid; Dioxoles; Dose-Response Relationship, Drug; Female; Humans; Lignans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Octanes; Pilot Projects; Sesame Oil; Time Factors | 2007 |
Suppression of ochratoxin biosynthesis by naturally occurring alkaloids.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Antioxidants; Aspergillus; Benzodioxoles; Carcinogens; Citrinin; Culture Media; Curcuma; Curcumin; Dioxolanes; Dioxoles; Food Contamination; Lignans; Mycelium; Mycotoxins; Ochratoxins; Piper; Piperidines; Polyunsaturated Alkamides; Sesame Oil | 2007 |
Sesamin, a lignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells.
Topics: Breast Neoplasms; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cyclin D; Cyclins; Dioxoles; Down-Regulation; G1 Phase; Growth Inhibitors; Humans; Lignans; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Mas; Retinoblastoma Protein; Sesame Oil | 2007 |
Electrospray ionization ion-trap time-of-flight tandem mass spectrometry of two furofurans: sesamin and gmelinol.
Topics: Antihypertensive Agents; Bridged Bicyclo Compounds; Dioxoles; Lignans; Molecular Structure; Reproducibility of Results; Sesame Oil; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Dietary sesamin suppresses aortic NADPH oxidase in DOCA salt hypertensive rats.
Topics: Animals; Aorta; Cyclic N-Oxides; Desoxycorticosterone; Dietary Supplements; Dioxoles; Hypertension; Lignans; Male; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Spin Labels | 2008 |
Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells.
Topics: Animals; Aristolochiaceae; Cell Line; Dioxoles; Dose-Response Relationship, Drug; Lignans; Lipopolysaccharides; Mice; Microglia; Molecular Structure; Nitric Oxide; Plant Roots; Polyunsaturated Alkamides; Propiophenones; Stereoisomerism; Structure-Activity Relationship; Toluene | 2008 |
Effect of the form of the sesame-based diet on the absorption of lignans.
Topics: 4-Butyrolactone; Animal Nutritional Physiological Phenomena; Animals; Diet; Dioxoles; Food Analysis; Lignans; Male; Rats; Rats, Wistar; Seeds; Sesamum | 2008 |
HPTLC fingerprinting and quantification of lignans as markers in sesame oil and its polyherbal formulations.
Topics: Biomarkers; Calibration; Chromatography, Thin Layer; Dioxoles; Lignans; Medicine, Ayurvedic; Methanol; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Oils; Reference Standards; Reproducibility of Results; Seeds; Sensitivity and Specificity; Sesame Oil; Sesamum; Solvents; Spectrophotometry, Ultraviolet; Time Factors | 2008 |
Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Dioxoles; Drug Synergism; Female; Food, Formulated; Lignans; Liver; Mice; Mice, Hairless; Palm Oil; Papilloma; Plant Oils; Skin; Skin Neoplasms; Sunburn; Thiobarbituric Acid Reactive Substances; Tocotrienols; Ultraviolet Rays; Vitamin E | 2008 |
Sesamin supplementation increases white muscle docosahexaenoic acid (DHA) levels in rainbow trout (Oncorhynchus mykiss) fed high alpha-linolenic acid (ALA) containing vegetable oil: metabolic actions.
Topics: alpha-Linolenic Acid; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Cytochrome P-450 CYP1A1; Dioxoles; Docosahexaenoic Acids; Lignans; Liver; Muscle Fibers, Fast-Twitch; Oncorhynchus mykiss; Plant Oils | 2008 |
Sesamin increases alpha-linolenic acid conversion to docosahexaenoic acid in atlantic salmon (Salmo salar L.) hepatocytes: role of altered gene expression.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Dioxoles; Docosahexaenoic Acids; Gene Expression Regulation; Hepatocytes; Lignans; Models, Biological; PPAR alpha; Salmo salar; Stearoyl-CoA Desaturase | 2008 |
Effect of schisandrin B and sesamin mixture on CCl(4)-induced hepatic oxidative stress in rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooctanes; Dioxoles; Drug Combinations; Drugs, Chinese Herbal; Glutathione; Glutathione Peroxidase; Lignans; Liver; Liver Diseases; Male; Oxidative Stress; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Silymarin; Superoxide Dismutase | 2009 |
First chemical synthesis of antioxidative metabolites of sesamin.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dioxoles; Hydrolysis; Indicators and Reagents; Lignans; Magnetic Resonance Spectroscopy; Organometallic Compounds; Spectrometry, Mass, Electrospray Ionization | 2008 |
Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils.
Topics: 4-Butyrolactone; Amides; Benzamides; Benzene Derivatives; Benzodioxoles; Coumarins; Dioxoles; Humans; Inhibitory Concentration 50; Lignans; Molecular Structure; Neutrophils; Pancreatic Elastase; Plant Bark; Plants, Medicinal; Superoxides; Taiwan; Zanthoxylum | 2009 |
Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus.
Topics: Animals; Benzodioxoles; Diet; Dioxoles; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Lignans; Male; Phenols; Phytoestrogens; Prostate; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesamum; Uterus | 2009 |
Sesamin as a co-initiator for unfilled dental restorations.
Topics: Animals; Cell Line; Cell Survival; Dental Implants; Dioxoles; Fibroblasts; Light-Curing of Dental Adhesives; Lignans; Materials Testing; Mice; Resins, Synthetic | 2009 |
Metabolites of sesamin, a major lignan in sesame seeds, induce neuronal differentiation in PC12 cells through activation of ERK1/2 signaling pathway.
Topics: Animals; Antioxidants; Cell Differentiation; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Lignans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Nerve Growth Factor; Neural Pathways; Neurogenesis; Neurons; PC12 Cells; Phosphorylation; Rats; Receptor, trkA; Synapses; Synaptophysin | 2009 |
Use of high resolution LC-MSn analysis in conjunction with mechanism-based stress studies: identification of asarinin, an impurity from sesame oil in an animal health product.
Topics: Animals; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dioxoles; Drug Contamination; Drug Stability; Ions; Lignans; Pharmaceutical Preparations; Sesame Oil; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Veterinary Drugs | 2009 |
Sesamin improves endothelial dysfunction in renovascular hypertensive rats fed with a high-fat, high-sucrose diet.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Dietary Carbohydrates; Dietary Fats; Dioxoles; Endothelium, Vascular; Gene Expression Regulation; Hypertension, Renovascular; Lignans; Lipids; Male; Malondialdehyde; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Sucrose; Tyrosine | 2009 |
Assessing the neuroprotective effect of antioxidative food factors by application of lipid-derived dopamine modification adducts.
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Curcumin; Dioxoles; Dopamine; Food; Humans; Lignans; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Tandem Mass Spectrometry; Tocopherols; Tocotrienols; Xanthophylls | 2009 |
Sesamin attenuates behavioral, biochemical and histological alterations induced by reversible middle cerebral artery occlusion in the rats.
Topics: Animals; Antioxidants; Behavior, Animal; Dioxoles; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Infarction, Middle Cerebral Artery; Lignans; Male; Motor Activity; Neuroprotective Agents; Protein Carbonylation; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2010 |
Metabolic engineering of lignan biosynthesis in Forsythia cell culture.
Topics: Cell Culture Techniques; Cells, Cultured; Dioxoles; Forsythia; Furans; Gene Expression Regulation, Plant; Genetic Engineering; Lignans; Molecular Structure; Plant Leaves; Plants, Genetically Modified; RNA Interference; Transformation, Genetic | 2009 |
Angiogenic activity of sesamin through the activation of multiple signal pathways.
Topics: Androstadienes; Animals; Antioxidants; Cell Adhesion Molecules; Cells, Cultured; Dioxoles; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Focal Adhesion Kinase 1; Humans; Lignans; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Vascular Endothelial Growth Factor A; Wortmannin | 2010 |
Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein.
Topics: Apoptosis; Cells, Cultured; Dioxoles; E-Selectin; Endothelial Cells; Female; Gene Expression; Humans; Lignans; Lipoproteins, LDL; Oxidative Stress; Pregnancy; Reactive Oxygen Species | 2009 |
Antirejection effect of Herba Asari extract in rats after cardiac allograft implantation.
Topics: Animals; Antioxidants; Cyclosporine; Dioxoles; Drugs, Chinese Herbal; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lignans; Models, Molecular; Plant Extracts; Rats; Rats, Sprague-Dawley; Transplantation, Homologous | 2009 |
Sesamin inhibits bacterial formylpeptide-induced inflammatory responses in a murine air-pouch model and in THP-1 human monocytes.
Topics: Animals; Anti-Inflammatory Agents; Bacteria; Basophils; Bucladesine; Calcium; Cell Line; Cell Line, Tumor; Chemotaxis, Leukocyte; Dioxoles; Dose-Response Relationship, Drug; Humans; Inflammation; Leukemia; Leukemic Infiltration; Lignans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Models, Animal; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NF-kappa B; Phosphorylation; Phytotherapy; Plant Extracts; Rats; Receptors, Formyl Peptide; Sesamum; Signal Transduction | 2010 |
[Studies on the chemical constituents from Euphorbia chrysocoma].
Topics: Dioxoles; Diterpenes; Euphorbia; Lignans; Molecular Structure; Oleanolic Acid; Plant Components, Aerial; Plants, Medicinal; Sitosterols | 2009 |
Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts.
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Curcumin; Dioxoles; Dopamine; Humans; Lignans; Neuroblastoma; Parkinson Disease; Tandem Mass Spectrometry; Tocopherols; Tocotrienols; Xanthophylls | 2010 |
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Biflavonoids; Biomarkers; Catechin; Chlorogenic Acid; Cholesterol; Diet; Dioxoles; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; F2-Isoprostanes; Fatty Acids; Flavonoids; Heme Oxygenase-1; Inflammation; Leukotriene B4; Lignans; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; P-Selectin; Phenols; Polyphenols; Quercetin; Superoxides | 2010 |
Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Capsaicin; Cell Line, Tumor; Curcumin; Diet; Dioxoles; Gene Expression Regulation, Neoplastic; Genistein; Humans; Intestinal Mucosa; Isoflavones; Lignans | 2010 |
Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Surface; Antioxidants; Aorta; Apolipoproteins E; Atherosclerosis; Benzodioxoles; Cell Line; Cells, Cultured; Dioxoles; ELAV Proteins; ELAV-Like Protein 1; Endothelium, Vascular; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Lignans; Mice; Mice, Knockout; Monocytes; Phenols; Random Allocation; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha | 2010 |
Sesamin manifests chemopreventive effects through the suppression of NF-kappa B-regulated cell survival, proliferation, invasion, and angiogenic gene products.
Topics: Angiogenic Proteins; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dioxoles; Growth Inhibitors; Humans; Lignans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; NF-kappa B; Sesame Oil; Signal Transduction | 2010 |
Antioxidants from the leaves of Cinnamomum kotoense.
Topics: Antioxidants; Biphenyl Compounds; Cinnamomum; Dioxoles; Lignans; Molecular Structure; Oxidation-Reduction; Picrates; Plant Leaves | 2010 |
Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Culture Media, Conditioned; Dioxoles; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-6; Interleukin-8; Lignans; Macrophages; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neovascularization, Pathologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
A new 3,4-seco-lupane-type triterpenoid from the pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms.
Topics: Cyclooctanes; Dioxoles; Eleutherococcus; Furans; Lignans; Molecular Structure; Plants, Medicinal; Polycyclic Compounds; Triterpenes | 2010 |
Metabolism of sesamin by cytochrome P450 in human liver microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dioxoles; Humans; Isoenzymes; Lignans; Microsomes, Liver | 2010 |
Genotoxicity evaluation of sesamin and episesamin.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Comet Assay; Cricetinae; Cricetulus; Dioxoles; DNA Damage; Dose-Response Relationship, Drug; Erythrocytes; Lignans; Liver Extracts; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; Microsomes, Liver; Molecular Structure; Mutagenicity Tests; Mutation; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Sesame Oil | 2011 |
Influence of dietary sesamin, a bioactive compound on fatty acids and expression of some lipid regulating genes in Baltic Atlantic salmon (Salmo salar L.) juveniles.
Topics: Animals; Cytochrome P-450 CYP1A1; Dioxoles; Fatty Acids; Lignans; Lipid Metabolism; Liver; Salmo salar; Tocopherols | 2011 |
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Separation; Comet Assay; Dioxoles; DNA Damage; Flow Cytometry; Humans; Lignans; Lung Neoplasms; Mitochondria; Molecular Sequence Data; Protease La; Protein Structure, Quaternary; Signal Transduction | 2010 |
Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.
Topics: Animals; Apoptosis; Dioxoles; Heme Oxygenase-1; Hydrogen Peroxide; Lignans; NF-E2-Related Factor 2; PC12 Cells; Rats; Seedlings; Sesamum | 2011 |
The mechanism underlying the synergetic hypocholesterolemic effect of sesamin and α-tocopherol in rats fed a high-cholesterol diet.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antioxidants; Apolipoproteins A; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Diet, Atherogenic; Dioxoles; Drug Synergism; Gene Expression; Gene Expression Profiling; Lignans; Lipoproteins; Liver; Male; Rats; Rats, Sprague-Dawley | 2011 |
Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2.
Topics: Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dioxoles; Gene Silencing; HT29 Cells; Humans; Lignans; Phosphorylation; Receptor, EphA1; Receptor, EphB2; Tyrosine | 2011 |
Experimental antithrombotic effects of sesame seed whole grains and extracts.
Topics: Administration, Oral; Animals; Benzodioxoles; Diet, High-Fat; Dioxoles; Disease Models, Animal; Edible Grain; Fibrinolytic Agents; Humans; Infusions, Intra-Arterial; Lasers; Lignans; Male; Mice; Mice, Inbred C57BL; Phenols; Plant Extracts; Sesamum; Thrombosis | 2011 |
Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation.
Topics: Animals; Antioxidants; Behavior, Animal; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dioxoles; Enzyme Activation; Kainic Acid; Lignans; Lipid Peroxidation; Male; Mice; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rhoA GTP-Binding Protein; Status Epilepticus | 2011 |
Sequential metabolism of sesamin by cytochrome P450 and UDP-glucuronosyltransferase in human liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronides; Glucuronosyltransferase; Humans; Intestine, Small; Isoenzymes; Lignans; Liver; Male; Methylation; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2011 |
Sesamin induces melanogenesis by microphthalmia-associated transcription factor and tyrosinase up-regulation via cAMP signaling pathway.
Topics: Animals; Antioxidants; Cyclic AMP; Dioxoles; Lignans; Melanoma; Melanosomes; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Signal Transduction; Up-Regulation | 2011 |
(+)-Episesamin exerts anti-neoplastic effects in human hepatocellular carcinoma cell lines via suppression of nuclear factor-kappa B and inhibition of MMP-9.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Proliferation; Dioxoles; Humans; Interleukin-6; Lignans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Invasiveness; NF-kappa B; Vascular Endothelial Growth Factor A | 2012 |
Fatty acids and gene expression responses to bioactive compounds in Atlantic salmon (Salmo salar L.) hepatocytes.
Topics: Animals; Cell Separation; Cell Survival; Culture Media; Dioxoles; DNA, Complementary; Fatty Acids; Gene Expression; Genistein; Hepatocytes; In Vitro Techniques; Indicators and Reagents; Lignans; Lipid Metabolism; Peroxisome Proliferator-Activated Receptors; Real-Time Polymerase Chain Reaction; Salmo salar; Thioctic Acid | 2011 |
Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice.
Topics: Animals; Apoptosis; Body Weight; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Dioxoles; Eating; Estrogens; Female; Flax; Glucosides; Humans; Lignans; Mice; Mice, Nude; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Seeds; Sesamum; Signal Transduction; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2012 |
Modulatory effects of sesamin on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.
Topics: Animals; Cell Survival; Cytotoxins; Dioxoles; Dopamine; Dose-Response Relationship, Drug; Levodopa; Lignans; PC12 Cells; Rats; Reactive Oxygen Species; Seeds; Sesamum | 2012 |
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diclofenac; Dioxoles; Ellipticines; Fish Proteins; Fluconazole; Hydroxylation; Ketoconazole; Kinetics; Lignans; Microsomes, Liver; Oxazines; Salmo salar; Sulfaphenazole; Tolbutamide | 2012 |
A phytochemical investigation of Zanthoxylum setulosum.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Costa Rica; Dioxoles; Humans; Lignans; Magnetic Resonance Spectroscopy; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Zanthoxylum | 2011 |
Sesamin exerts renoprotective effects by enhancing NO bioactivity in renovascular hypertensive rats fed with high-fat-sucrose diet.
Topics: Animals; Antihypertensive Agents; Antioxidants; Diet, High-Fat; Dietary Sucrose; Dioxoles; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Hypertension, Renovascular; Hypolipidemic Agents; Kidney; Kidney Cortex; Lignans; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Sprague-Dawley; Tyrosine; Up-Regulation | 2012 |
Interrelated effects of dihomo-γ-linolenic and arachidonic acids, and sesamin on hepatic fatty acid synthesis and oxidation in rats.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Cell Extracts; Corn Oil; Dioxoles; Fatty Acids; Fungi; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Lignans; Lipids; Lipogenesis; Lipolysis; Liver; Male; Oxidation-Reduction; Peroxisomes; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
[Anti-lipotoxic action of sesamin on renovascular hypertensive rats fed with a high-fat, high-sucrose diet].
Topics: Adipocytes; Animals; Anticholesteremic Agents; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Diet, High-Fat; Dioxoles; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hypertension, Renovascular; Insulin; Insulin Resistance; Interleukin-6; Islets of Langerhans; Lignans; Liver; Male; Pancreas; Rats; Rats, Sprague-Dawley; Sucrose; Triglycerides; Tumor Necrosis Factor-alpha | 2012 |
Quercetin and sesamin protect neuronal PC12 cells from high-glucose-induced oxidation, nitrosative stress, and apoptosis.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cytoprotection; Dioxoles; Enzyme Activation; Fluorescent Antibody Technique; Free Radicals; Glucose; Lignans; Neurons; Nitrosation; Oxidation-Reduction; PC12 Cells; Poly(ADP-ribose) Polymerases; Protective Agents; Quercetin; Rats; Stress, Physiological; Superoxide Dismutase | 2012 |
Sesamin stimulates osteoblast differentiation through p38 and ERK1/2 MAPK signaling pathways.
Topics: Cell Differentiation; Dioxoles; Female; Gene Expression; Humans; Lignans; MAP Kinase Signaling System; Osteoblasts; Osteoporosis; p38 Mitogen-Activated Protein Kinases; Sesamum; Up-Regulation | 2012 |
Identification of the metabolites of episesamin in rat bile and human liver microsomes.
Topics: Animals; Bile; Biological Availability; Cytochrome P-450 Enzyme System; Dioxoles; Humans; Isomerism; Lignans; Microsomes, Liver; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Sesame Oil; Sesamum | 2012 |
Chondroprotective and anti-inflammatory effects of sesamin.
Topics: Animals; Anti-Inflammatory Agents; Cartilage; Chondrocytes; Collagen Type II; Dioxoles; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glycosaminoglycans; Humans; Hydroxyproline; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lignans; MAP Kinase Signaling System; Matrix Metalloproteinases; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Papain; Phosphorylation; Proteoglycans; Rats; Swine | 2012 |
Comparison of metabolism of sesamin and episesamin by drug-metabolizing enzymes in human liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Dioxoles; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Kinetics; Lignans; Liver; Male; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Protein Conformation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substrate Specificity | 2012 |
Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats.
Topics: Animals; Appetite Depressants; Carnitine; Dietary Supplements; Dioxoles; Fatty Acids; Gene Expression Regulation, Enzymologic; Hypolipidemic Agents; Lignans; Lipid Metabolism; Lipogenesis; Lipolysis; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thioctic Acid; Triglycerides; Weight Gain | 2013 |
Sesamin modulates gene expression without corresponding effects on fatty acids in Atlantic salmon (Salmo salar L.).
Topics: Animals; Diet; Dietary Supplements; Dioxoles; Fatty Acids; Gene Expression Regulation; Lignans; Salmon | 2012 |
(+)-Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 (pre)adipocytes by sustained Wnt signaling, down-regulation of PPARγ and induction of iNOS.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Inflammatory Agents; beta Catenin; Caspase 3; Caspase 7; Cell Differentiation; Dioxoles; Down-Regulation; Glucose Transporter Type 4; Inflammation; Interleukin-6; Lignans; Lindera; Lipid Metabolism; Liver; Mice; Nitric Oxide Synthase Type II; Obesity; Phosphorylation; Plant Extracts; PPAR gamma; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Wnt Signaling Pathway | 2013 |
Plasma and tissue concentrations of α-tocopherol and δ-tocopherol following high dose dietary supplementation in mice.
Topics: Adipose Tissue; alpha-Tocopherol; Animals; Antioxidants; Brain Chemistry; Dietary Supplements; Dioxoles; Lignans; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Tocopherols; Vitamin E; Vitamin E Deficiency; Vitamins | 2012 |
Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Coculture Techniques; Cytokines; Cytoprotection; Dioxoles; Dopaminergic Neurons; Gene Expression Regulation; Inflammation; Kinetics; Lignans; Mice; Microglia; Mitochondria; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidative Stress; PC12 Cells; Quercetin; Rats; RNA, Messenger; Superoxides | 2012 |
Mechanisms mediating the synergistic anticancer effects of combined γ-tocotrienol and sesamin treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Count; Cell Line, Tumor; Cell Survival; Chromans; Dioxoles; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lignans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-raf; Receptor, ErbB-3; STAT1 Transcription Factor; Vitamin E | 2012 |
The sesame lignan sesamin attenuates vascular dysfunction in streptozotocin diabetic rats: involvement of nitric oxide and oxidative stress.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Dioxoles; Dose-Response Relationship, Drug; In Vitro Techniques; Lignans; Male; Nitric Oxide; Oxidative Stress; Prostaglandins; Rats; Rats, Wistar; Sesamum; Vasoconstriction | 2013 |
In vitro inhibition of 7-ethoxyresorufin-O-deethylase (EROD) and p-nitrophenol hydroxylase (PNPH) activities by sesamin in hepatic microsomes from two fish species.
Topics: Animals; Antioxidants; Carps; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2E1 Inhibitors; Dioxoles; Inhibitory Concentration 50; Kinetics; Lignans; Microsomes, Liver; Salmon | 2013 |
Sesamin suppresses activation of microglia and p44/42 MAPK pathway, which confers neuroprotection in rat intracerebral hemorrhage.
Topics: Animals; Antioxidants; Brain; Cell Death; Cell Proliferation; Cells, Cultured; Cerebral Hemorrhage; Dioxoles; Disease Models, Animal; Lignans; Male; MAP Kinase Signaling System; Microglia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Rats, Wistar | 2013 |
Long-term intake of sesamin improves left ventricular remodelling in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Collagen Type I; Dioxoles; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hypertension; Hypertrophy, Left Ventricular; Lignans; Male; Malondialdehyde; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine; Ventricular Remodeling | 2013 |
Hypoglycaemic and hypolipidaemic activities of sesamin from sesame meal and its ability to ameliorate insulin resistance in KK-Ay mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dioxoles; Female; Glutathione; Glutathione Peroxidase; Hypoglycemic Agents; Insulin Resistance; Lignans; Lipids; Mice; Mice, Inbred C57BL; Sesamum; Superoxide Dismutase | 2013 |
Sesamin synergistically potentiates the anticancer effects of γ-tocotrienol in mammary cancer cell lines.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chromans; Cyclin-Dependent Kinase Inhibitor Proteins; Cyclins; Dioxoles; Drug Synergism; Drug Therapy, Combination; E2F1 Transcription Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; Mice; Molecular Structure; Retinoblastoma Protein; Vitamin E | 2013 |
(±)-Asarinin.
Topics: Crystallography, X-Ray; Dioxoles; Drugs, Chinese Herbal; Hydrogen Bonding; Lignans; Molecular Structure; Stereoisomerism; Zanthoxylum | 2013 |
Sesamin extends the mean lifespan of fruit flies.
Topics: Animals; Antioxidants; Catalase; Dietary Supplements; Dioxoles; Drosophila; Drosophila Proteins; Endopeptidases; Gene Expression Regulation; Herbicides; Lignans; Longevity; Male; Models, Animal; Paraquat; Superoxide Dismutase | 2013 |
Evaluation of antioxidative effects of sesamin on the in vivo hepatic reducing abilities by a radiofrequency ESR method.
Topics: Administration, Oral; Animals; Antioxidants; Cyclic N-Oxides; Dioxoles; Electron Spin Resonance Spectroscopy; Half-Life; Lignans; Liver; Male; Molecular Structure; Oxidation-Reduction; Rats; Rats, Wistar; Spin Labels | 2013 |
Sesamin protects mouse liver against nickel-induced oxidative DNA damage and apoptosis by the PI3K-Akt pathway.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Blotting, Western; Caspase 3; Deoxyguanosine; Dioxoles; DNA Damage; Glutathione; In Situ Nick-End Labeling; Lignans; Lipid Peroxidation; Liver; Male; Mice; Nickel; Oncogene Protein v-akt; Oxidative Stress; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Signal Transduction; Thiobarbituric Acid Reactive Substances | 2013 |
Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo.
Topics: Animals; Capillary Permeability; Cell Adhesion; Cell Survival; Dioxoles; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Male; Mice; Mice, Inbred C57BL; Sesame Oil; Vasculitis | 2013 |
Sesamin modulation of lipid class and fatty acid profile in early juvenile teleost, Lates calcarifer, fed different dietary oils.
Topics: Animal Feed; Animals; Dietary Fats, Unsaturated; Dioxoles; Fatty Acids; Lignans; Lipid Metabolism; Lipids; Perciformes | 2012 |
Effects of sesamin on streptozotocin (STZ)-induced NIT-1 pancreatic β-cell damage.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Cell Line; Cell Survival; Dioxoles; Glutathione; Glutathione Peroxidase; Insulin-Secreting Cells; Lignans; Mice; Streptozocin; Superoxide Dismutase | 2012 |
Sesamin ameliorates arterial dysfunction in spontaneously hypertensive rats via downregulation of NADPH oxidase subunits and upregulation of eNOS expression.
Topics: Animals; Aorta, Thoracic; Dioxoles; Down-Regulation; Hypertension; Lignans; Male; NADPH Oxidases; Nitric Oxide Synthase Type III; Organ Culture Techniques; Protein Subunits; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation | 2013 |
Apoptosis inducing activity of benzophenanthridine-type alkaloids and 2-arylbenzofuran neolignans in HCT116 colon carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzophenanthridines; Dioxoles; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Indole Alkaloids; Lignans; Plants, Medicinal; Quinazolines; Quinolines; Zanthoxylum | 2013 |
Isolation of anti-tumor compounds from the stem bark of Zanthoxylum ailanthoides Sieb. & Zucc. by silica gel column and counter-current chromatography.
Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Line, Tumor; Cell Survival; Coumarins; Countercurrent Distribution; Dioxoles; Humans; Lignans; Plant Bark; Silica Gel; Zanthoxylum | 2013 |
Dietary sesame seed and its lignan, sesamin, increase tocopherol and phylloquinone concentrations in male rats.
Topics: Animals; Brain; Diet; Dioxoles; gamma-Tocopherol; Heart; Kidney; Lignans; Liver; Lung; Male; Rats; Rats, Wistar; Seeds; Sesamum; Testis; Vitamin K 1; Vitamin K 2 | 2013 |
Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Cells, Cultured; Dioxoles; Endothelial Protein C Receptor; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-1beta; Lignans; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Receptors, Cell Surface; Sepsis; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
Simultaneous determination of two epimeric furofuran lignans (sesamin and asarinin) of Asarum heterotropoides extract in rat plasma by LC/MS/MS: application to pharmacokinetic study.
Topics: Animals; Asarum; Chromatography, Liquid; Dioxoles; Lignans; Male; Plant Extracts; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Sesamin induces cell cycle arrest and apoptosis through the inhibition of signal transducer and activator of transcription 3 signalling in human hepatocellular carcinoma cell line HepG2.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Checkpoints; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dioxoles; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Interleukin-6; Lignans; Liver Neoplasms; Phytotherapy; Plant Extracts; Seeds; Sesamum; Signal Transduction; STAT3 Transcription Factor; Tumor Suppressor Protein p53 | 2013 |
[Isolation and identification of impurities in the natural vitamin E].
Topics: Chromatography, High Pressure Liquid; Dioxoles; Gas Chromatography-Mass Spectrometry; Lignans; Vitamin E | 2013 |
¹H NMR-based metabolomics studies on the effect of sesamin in Atlantic salmon (Salmo salar).
Topics: Animals; Dioxoles; Lignans; Liver; Magnetic Resonance Spectroscopy; Metabolomics; Muscles; Salmo salar | 2014 |
Sesamin ameliorates doxorubicin-induced cardiotoxicity: involvement of Sirt1 and Mn-SOD pathway.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Dioxoles; Doxorubicin; Heart; Lignans; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sirtuin 1; Superoxide Dismutase | 2014 |
Antithrombotic activities of epi-sesamin in vitro and in vivo.
Topics: Animals; Asarum; Bleeding Time; Blood Coagulation; Blood Coagulation Tests; Cysteine Endopeptidases; Dioxoles; Female; Fibrin; Fibrinolysis; Fibrinolytic Agents; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Mice; Mice, Inbred ICR; Neoplasm Proteins; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Polymerization; Structure-Activity Relationship; Thrombin; Tissue Plasminogen Activator | 2013 |
Hepatoprotective properties of sesamin against CCl4 induced oxidative stress-mediated apoptosis in mice via JNK pathway.
Topics: Animals; Apoptosis; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Dioxoles; Enzyme Activation; Lignans; Liver; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred ICR; Oxidative Stress; Phosphorylation; Reactive Oxygen Species | 2014 |
Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture.
Topics: Adolescent; Adult; Aggrecans; Cartilage, Articular; Cells, Cultured; Chondrocytes; Chondroitin Sulfate Proteoglycans; Dioxoles; Gene Expression Regulation; Glucuronosyltransferase; Glycosaminoglycans; Humans; Lignans; Middle Aged; Multifunctional Enzymes; N-Acetylgalactosaminyltransferases; Pentosyltransferases; UDP Xylose-Protein Xylosyltransferase; Young Adult | 2014 |
α-Tocopherol transfer protein is not required for the discrimination against γ-tocopherol in vivo but protects it from side-chain degradation in vitro.
Topics: alpha-Tocopherol; Animals; Carrier Proteins; Chromans; Dioxoles; Female; gamma-Tocopherol; Hep G2 Cells; Humans; Lignans; Liver; Mice; Mice, Knockout; Mixed Function Oxygenases; Oxidation-Reduction; Propionates | 2014 |
Sesamin and sesamolin as unexpected contaminants in various cold-pressed plant oils: NP-HPLC/FLD/DAD and RP-UPLC-ESI/MS(n) study.
Topics: Chromatography, Liquid; Dioxoles; Lignans; Plant Oils; Spectrometry, Mass, Electrospray Ionization | 2014 |
Protective effect of a sesamin derivative, 3-bis (3-methoxybenzyl) butane-1, 4-diol on ischemic and hypoxic neuronal injury.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood-Brain Barrier; Brain Ischemia; Butylene Glycols; Cell Hypoxia; Dioxoles; Humans; Lignans; Lipid Peroxidation; Mice; Microglia; Neurons; Neuroprotective Agents; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2014 |
Influence of oral supplementation with sesamin on longevity of Caenorhabditis elegans and the host defense.
Topics: Administration, Oral; Animals; Antioxidants; Caenorhabditis elegans; Dioxoles; Escherichia coli; gamma-Cyclodextrins; Insulin-Like Growth Factor I; Legionella pneumophila; Lignans; Longevity; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Carbonylation; Salmonella enterica; Signal Transduction | 2014 |
The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cluster Analysis; Dioxoles; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Profiling; HEK293 Cells; Humans; Lignans; Neoplasms; Phytotherapy; Plant Extracts | 2014 |
In vitro antitumoral activity of compounds isolated from Artemisia gorgonum Webb.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Cell Line; Cell Line, Tumor; Dioxoles; Flavonoids; Humans; Lignans; Mice; Plant Components, Aerial; Plant Extracts; Sesquiterpenes, Guaiane | 2014 |
Antimycobacterial furofuran lignans from the roots of Anemopsis californica.
Topics: Anti-Bacterial Agents; Bacteria; Dioxoles; Lignans; Microbial Sensitivity Tests; Plant Extracts; Plant Roots; Saururaceae | 2014 |
Open, sesame! The gateway to mitigate hepatic injury using sesamin.
Topics: Chemical and Drug Induced Liver Injury; Dioxoles; Humans; Lignans | 2014 |
Sesamin reduces acute hepatic injury induced by lead coupled with lipopolysaccharide.
Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Dioxoles; Lignans; Lipopolysaccharides; Male; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2014 |
Protective effects of the polyphenol sesamin on allergen-induced T(H)2 responses and airway inflammation in mice.
Topics: Active Transport, Cell Nucleus; Allergens; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dioxoles; Eosinophils; Immunoglobulin E; Lignans; Lung; Male; Mice, Inbred BALB C; Mucus; NF-kappa B; Th2 Cells | 2014 |
Antinociceptive and anti-inflammatory activities of the sesame oil and sesamin.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dioxoles; Edema; Formaldehyde; Inflammation; Lignans; Male; Mice; Nociception; Pain; Pleurisy; Rats; Rats, Wistar; Sesame Oil; Toxicity Tests, Acute | 2014 |
Sesamin enhances cholesterol efflux in RAW264.7 macrophages.
Topics: Animals; Biological Transport; Cell Line; Cholesterol; Dioxoles; Lignans; Macrophages; Mice | 2014 |
[Study on chemical constituents of Zanthoxyli cortex's ethyl acetate extract].
Topics: Acetates; Benzodioxoles; Dioxoles; Furans; Lignans; Magnetic Resonance Spectroscopy; Plant Bark; Plant Extracts; Rutaceae; Triterpenes | 2013 |
The effect of sesamin on airway fibrosis in vitro and in vivo.
Topics: Actins; Animals; Basement Membrane; Cell Line; Cell Proliferation; Collagen Type I; Dioxoles; Down-Regulation; Epithelial-Mesenchymal Transition; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Humans; Lignans; Lung Diseases; Mice; Mice, Inbred C57BL; Respiratory Mucosa; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2014 |
Differentiation therapy: sesamin as an effective agent in targeting cancer stem-like side population cells of human gallbladder carcinoma.
Topics: Analysis of Variance; Animals; Cadherins; Carcinoma; Cell Differentiation; Cell Line, Tumor; Dioxoles; Female; Gallbladder Neoplasms; Humans; Interleukin-6; Lignans; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Side-Population Cells; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Protective effect of a sesamin derivative, 3-bis (3-methoxybenzyl) butane-1, 4-diol on Aβ-stressed PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Butylene Glycols; Cell Survival; Dioxoles; Lignans; MAP Kinase Signaling System; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Rats | 2015 |
[Chemical constituents of pattra medicine Euodia lepta].
Topics: China; Coumaric Acids; Dioxoles; Evodia; Furocoumarins; Lignans; Plant Leaves; Plant Stems; Sitosterols | 2014 |
Sesamin suppresses macrophage-derived chemokine expression in human monocytes via epigenetic regulation.
Topics: Anti-Inflammatory Agents; Asthma; Cell Line, Tumor; Chemokine CCL22; Chemokine CXCL1; Chemokine CXCL10; Dioxoles; Epigenesis, Genetic; Histones; Humans; Lignans; Lipopolysaccharides; Monocytes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR alpha; Promoter Regions, Genetic; Receptors, Estrogen; Seeds; Sesamum; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Gene expression profiling of sesaminol triglucoside and its tetrahydrofuranoid metabolites in primary rat hepatocytes.
Topics: 4-Butyrolactone; Animals; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Gene Expression; Gene Expression Profiling; Glucosides; Hepatocytes; Inactivation, Metabolic; Lignans; Liver; Mammals; Plant Extracts; Rats, Sprague-Dawley; Seeds; Sesamum | 2014 |
[Protective effect of sesamin against myocardial injury induced by cadmium chloride in rats].
Topics: Animals; Cadmium Chloride; Creatine Kinase, MB Form; Dioxoles; Heart; Lignans; Male; Malondialdehyde; Myocardium; Rats; Rats, Wistar | 2014 |
Sesamin increases heme oxygenase-1 protein in RAW 264.7 macrophages through inhibiting its ubiquitination process.
Topics: Animals; Cell Line; Dioxoles; HEK293 Cells; Heme Oxygenase-1; Humans; Lignans; Macrophages; Membrane Proteins; Mice; Sesame Oil; Ubiquitination; Up-Regulation | 2014 |
The lignan (+)-episesamin interferes with TNF-α-induced activation of VSMC via diminished activation of NF-ĸB, ERK1/2 and AKT and decreased activity of gelatinases.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Movement; Cell Proliferation; Dioxoles; Dose-Response Relationship, Drug; Enzyme Activation; Gelatinases; Humans; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke.
Topics: Animals; Brain Ischemia; Dioxoles; Disease Models, Animal; Encephalitis; Infarction, Middle Cerebral Artery; Lignans; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Oxidative Stress; Signal Transduction; Stroke | 2014 |
Sesamin suppresses STZ induced INS-1 cell apoptosis through inhibition of NF-κB activation and regulation of Bcl-2 family protein expression.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cell Survival; Dioxoles; Gene Expression Regulation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Intracellular Space; Lignans; Malondialdehyde; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Signal Transduction; Streptozocin | 2015 |
Stimulatory effect of sesamin on hepatic cytochrome P450 activities in Atlantic salmon (Salmo salar L.) is not directly associated with expression of genes related to xenobiotic metabolism.
Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Fish Oils; Gene Expression Regulation; Lignans; Liver; Plant Oils; Salmo salar; Xenobiotics | 2015 |
Cholesterol-lowering activity of sesamin is associated with down-regulation on genes of sterol transporters involved in cholesterol absorption.
Topics: Animals; Anticholesteremic Agents; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cricetinae; Dioxoles; Down-Regulation; Humans; Hypercholesterolemia; Intestinal Mucosa; Intestines; Lignans; Liver X Receptors; Male; Mesocricetus; Orphan Nuclear Receptors; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2 | 2015 |
Comparative effects of sesame seeds differing in lignan contents and composition on fatty acid oxidation in rat liver.
Topics: Animals; Dioxoles; Fatty Acids; Lignans; Lipogenesis; Liver; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Seeds; Sesamum; Solubility; Triglycerides | 2015 |
Tracking sesamin synthase gene expression through seed maturity in wild and cultivated sesame species--a domestication footprint.
Topics: Base Sequence; Biosynthetic Pathways; Dioxoles; Gene Expression; Genotype; Lignans; Molecular Sequence Data; Phylogeny; Seeds; Sequence Analysis, DNA; Sesamum; Species Specificity | 2015 |
The effect of Asarinin on Toll-like pathway in rats after cardiac allograft implantation.
Topics: Allografts; Animals; Antioxidants; Cyclosporine; Dioxoles; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Interleukin-12; Lignans; Male; Models, Animal; Myocardium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, CXCR3; Toll-Like Receptor 4; Transplantation, Homologous | 2015 |
Suppression of TGF-β1/Smad signaling pathway by sesamin contributes to the attenuation of myocardial fibrosis in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Collagen Type I; Collagen Type III; Dioxoles; Fibroblasts; Fibrosis; Heart Ventricles; Lignans; Male; Malondialdehyde; Myocardium; NADPH Oxidases; Organ Size; Phosphorylation; Rats, Inbred SHR; Signal Transduction; Smad3 Protein; Smad7 Protein; Superoxide Dismutase; Systole; Transforming Growth Factor beta1 | 2015 |
Anxiolytic effects of sesamin in mice with chronic inflammatory pain.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Chronic Pain; Dietary Supplements; Dioxoles; Disease Models, Animal; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Lignans; Male; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuralgia; Neuritis; Neurons; Neuroprotective Agents; Phosphorylation; Pressure; Protein Processing, Post-Translational | 2016 |
Identification of MMP-1 and MMP-9 inhibitors from the roots of Eleutherococcus divaricatus, and the PAMPA test.
Topics: Dioxoles; Eleutherococcus; Gas Chromatography-Mass Spectrometry; Lignans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Plant Roots; Solubility; Theophylline; Triterpenes; Ursolic Acid; Verapamil | 2016 |
The anti-atherogenic properties of sesamin are mediated via improved macrophage cholesterol efflux through PPARγ1-LXRα and MAPK signaling.
Topics: Animals; Anticholesteremic Agents; Cells, Cultured; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Dioxoles; Lignans; Liver X Receptors; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Orphan Nuclear Receptors; PPAR gamma; Signal Transduction; Transfection; Up-Regulation | 2014 |
Sesamin inhibits lipopolysaccharide-induced proliferation and invasion through the p38-MAPK and NF-κB signaling pathways in prostate cancer cells.
Topics: Cell Line, Tumor; Cell Proliferation; Cytokines; Dioxoles; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lignans; Lipopolysaccharides; Male; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostatic Neoplasms; Pyridines; Signal Transduction | 2015 |
Sesamin ameliorates lipopolysaccharide/d-galactosamine-induced fulminant hepatic failure by suppression of Toll-like receptor 4 signaling in mice.
Topics: Animals; Antioxidants; Cell Line; Dioxoles; Galactosamine; Lignans; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Protective Agents; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Characterization of the Fluorescent Spectra and Intensities of Various Lignans: Application to HPLC Analysis with Fluorescent Detection†.
Topics: Benzodioxoles; Chromatography, High Pressure Liquid; Dioxoles; Lignans; Phenols; Sensitivity and Specificity; Spectrometry, Fluorescence | 2015 |
Evaluation of plant growth regulatory activity of furofuran lignan bearing a 7,9':7',9-diepoxy structure using optically pure (+)- and (-)-enantiomers.
Topics: Dioxoles; Lactuca; Lignans; Lolium; Molecular Structure; Plant Growth Regulators; Plant Roots; Plant Shoots; Stereoisomerism | 2015 |
Effect of sesamin on apoptosis and cell cycle arrest in human breast cancer mcf-7 cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Checkpoint Kinase 2; Dioxoles; Female; Humans; Lignans; Tumor Cells, Cultured | 2015 |
Sesamin enhances nitric oxide bioactivity in aortas of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Blotting, Western; Dioxoles; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Hypertension; Lignans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase; Up-Regulation | 2015 |
Sesamin Ameliorates Advanced Glycation End Products-Induced Pancreatic β-Cell Dysfunction and Apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Dioxoles; Glycation End Products, Advanced; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lignans; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species | 2015 |
Sesamin ameliorates oxidative liver injury induced by carbon tetrachloride in rat.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dioxoles; Disease Models, Animal; Lignans; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar | 2015 |
Sesamin Inhibits PDGF-Mediated Proliferation of Vascular Smooth Muscle Cells by Upregulating p21 and p27.
Topics: Animals; Aorta; Cell Cycle; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dioxoles; Lignans; Myocytes, Smooth Muscle; Phosphorylation; Platelet-Derived Growth Factor; Rats; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2015 |
[Effect of sesamin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary hypertension].
Topics: Animals; Dioxoles; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Hypertension, Pulmonary; Lignans; Lung; Male; Membrane Glycoproteins; Monocrotaline; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2015 |
Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt's lymphoma cells.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cell Line, Tumor; Cytotoxicity, Immunologic; Dioxoles; Humans; Killer Cells, Natural; Lignans; MAP Kinase Signaling System; Molecular Targeted Therapy; NK Cell Lectin-Like Receptor Subfamily K; Seeds; Sesamum; Up-Regulation | 2015 |
Sesamin prevents decline in exercise capacity and impairment of skeletal muscle mitochondrial function in mice with high-fat diet-induced diabetes.
Topics: Animals; Body Weight; Cell Line; Diabetes Mellitus, Experimental; Diet, High-Fat; Dioxoles; Exercise Tolerance; Lignans; Male; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; NADPH Oxidases; Oxidative Stress; Physical Conditioning, Animal; Superoxides | 2015 |
Protective properties of sesamin against fluoride-induced oxidative stress and apoptosis in kidney of carp (Cyprinus carpio) via JNK signaling pathway.
Topics: Animals; Apoptosis; Carps; Caspase 3; Dioxoles; Fluorides; Glutathione; Kidney; Lignans; Lipid Peroxidation; MAP Kinase Signaling System; Mitochondria; Oxidative Stress; Phosphates; Reactive Oxygen Species; Signal Transduction; Water Pollutants, Chemical | 2015 |
Combined Analysis of Stable Isotope, (1)H NMR, and Fatty Acid To Verify Sesame Oil Authenticity.
Topics: Carbon Isotopes; Dioxoles; Fatty Acids; Lignans; Magnetic Resonance Spectroscopy; Sesame Oil | 2015 |
Antileishmanial Activity of Compounds Isolated from Sassafras albidum.
Topics: Dioxoles; Fatty Alcohols; Leishmania; Lignans; Microbial Sensitivity Tests; Plant Extracts; Sassafras; Sitosterols; Trypanocidal Agents | 2015 |
Effect of sesamin against cytokine production from influenza type A H1N1-induced peripheral blood mononuclear cells: computational and experimental studies.
Topics: Animals; Crystallography, X-Ray; Dioxoles; Humans; Inflammation; Influenza A Virus, H1N1 Subtype; Influenza, Human; Interleukin-1beta; Interleukin-2; Leukocytes, Mononuclear; Lignans; Models, Molecular; Molecular Dynamics Simulation; Orthomyxoviridae Infections; Signal Transduction; Swine; Swine Diseases; Tumor Necrosis Factor-alpha | 2016 |
Protective effects of sesamin on liver fibrosis through antioxidative and anti-inflammatory activities in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carbon Tetrachloride Poisoning; Dioxoles; Lignans; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley | 2015 |
Sesamin Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibition of TLR4 Signaling Pathways.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Dioxoles; Edema; Enzyme Activation; Interleukin-1beta; Interleukin-6; Lignans; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Sesamin attenuates mast cell-mediated allergic responses by suppressing the activation of p38 and nuclear factor-κB.
Topics: 2,4-Dinitrophenol; Animals; Calcium; Cell Line; Cell Survival; Cytokines; Dioxoles; Enzyme Activation; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; Inflammation Mediators; Lignans; Male; Mast Cells; Mice, Inbred ICR; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Peritoneum; Rats, Sprague-Dawley | 2016 |
Recommended Daily Dose of Sesame Lignans Has No Influence on Oral Absorption of P-Glycoprotein Substrates in Rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Dioxoles; Drug Interactions; Food-Drug Interactions; Humans; Intestinal Absorption; Lignans; Male; Plant Extracts; Rats, Wistar; Rhodamine 123; Seeds; Sesamum; Terfenadine | 2015 |
[Effect of Serum Containing Sesamin on Angiotensin II-Induced Apoptosis in Rat Cardiomyocytes].
Topics: Angiotensin II; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cell Survival; Dioxoles; Lignans; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2015 |
Preparative separation of sesamin and sesamolin from defatted sesame meal via centrifugal partition chromatography with consecutive sample injection.
Topics: Centrifugation; Chromatography, Liquid; Dioxoles; Hep G2 Cells; Humans; Lignans; Plant Extracts; Sesamum | 2016 |
[Analytical Methods with Qualitative HPLC Fingerprint and Quantitative Measurement of Effective Components of Processed Asari Radix et Rhizoma].
Topics: Asarum; Chromatography, High Pressure Liquid; Dioxoles; Drugs, Chinese Herbal; Eugenol; Lignans; Plant Roots; Quality Control; Rhizome | 2015 |
Sesamin inhibits lipopolysaccharide-induced inflammation and extracellular matrix catabolism in rat intervertebral disc.
Topics: Animals; Cell Movement; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dioxoles; Enzyme Activation; Extracellular Matrix; Inflammation; Interleukin-1beta; Intervertebral Disc; Intervertebral Disc Degeneration; JNK Mitogen-Activated Protein Kinases; Lignans; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nucleus Pulposus; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Sesamin Ameliorates High-Fat Diet-Induced Dyslipidemia and Kidney Injury by Reducing Oxidative Stress.
Topics: Actins; Animals; Collagen Type IV; Diet, High-Fat; Dietary Fats; Dioxoles; Dose-Response Relationship, Drug; Dyslipidemias; Gene Expression Regulation; Kidney Diseases; Lignans; Molecular Structure; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Blood Glucose; Body Weight; Calcium-Binding Proteins; Diabetic Retinopathy; Dioxoles; Disease Models, Animal; Intercellular Adhesion Molecule-1; Lignans; Mice; Microfilament Proteins; Microglia; Nitric Oxide Synthase Type II; Retina; RNA, Messenger; Streptozocin; Tumor Necrosis Factor-alpha; Up-Regulation | 2016 |
Synthesis of furofuran lignans as antidiabetic agents simultaneously achieved by inhibiting α-glucosidase and free radical.
Topics: alpha-Glucosidases; Animals; Dioxoles; Free Radicals; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lignans; Rats | 2016 |
Ex vivo model exhibits protective effects of sesamin against destruction of cartilage induced with a combination of tumor necrosis factor-alpha and oncostatin M.
Topics: Animals; Arthritis, Rheumatoid; Cartilage; Dioxoles; Immunohistochemistry; Lignans; Models, Biological; Oncostatin M; Protective Agents; Swine; Tumor Necrosis Factor-alpha | 2016 |
Discovery of a sesamin-metabolizing microorganism and a new enzyme.
Topics: Dioxoles; Kinetics; Lignans; Micrococcaceae; Mutation; Soil Microbiology; Substrate Specificity | 2016 |
Determination and purification of sesamin and sesamolin in sesame seed oil unsaponified matter using reversed-phase liquid chromatography coupled with photodiode array and tandem mass spectrometry and high-speed countercurrent chromatography.
Topics: Chromatography, Reverse-Phase; Countercurrent Distribution; Dioxoles; Lignans; Sesame Oil; Sesamum; Tandem Mass Spectrometry | 2016 |
Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytochrome P-450 CYP2E1; Diet, High-Fat; Dioxoles; Dyslipidemias; Hypolipidemic Agents; Inflammation; Interleukin-6; Lignans; Lipid Metabolism; Lipids; Lipogenesis; Liver; Liver X Receptors; Male; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phytotherapy; Plant Extracts; PPAR alpha; Rats, Sprague-Dawley; Sesamum; Tumor Necrosis Factor-alpha | 2016 |
Phytochemicals prevent mitochondrial membrane permeabilization and protect SH-SY5Y cells against apoptosis induced by PK11195, a ligand for outer membrane translocator protein.
Topics: Apoptosis; Calcium; Cations, Divalent; Cell Line, Tumor; Cell Survival; Coumaric Acids; Dioxoles; Humans; Hydrophobic and Hydrophilic Interactions; Isoquinolines; Lignans; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Neuroprotective Agents; Oxygen; Permeability; Phytochemicals; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Xanthophylls | 2017 |
Magnetic solid-phase extraction based on graphene oxide for the determination of lignans in sesame oil.
Topics: Benzodioxoles; Chromatography, High Pressure Liquid; Dioxoles; Graphite; Lignans; Magnetic Phenomena; Phenols; Sesame Oil; Solid Phase Extraction | 2017 |
Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS.
Topics: Amides; Apigenin; Benzodioxoles; Catechin; Chromatography, High Pressure Liquid; Coumarins; Dioxoles; Flavonoids; Furans; Hesperidin; Hydroxybenzoates; Lignans; Limit of Detection; Plant Leaves; Powders; Reproducibility of Results; Seasons; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zanthoxylum | 2017 |
Effects of (-)-sesamin on chronic stress-induced memory deficits in mice.
Topics: Animals; Avoidance Learning; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dioxoles; Dopamine; Electroshock; Hippocampus; Lignans; Male; Maze Learning; Memory Disorders; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spatial Memory; Stereoisomerism; Stress, Physiological | 2016 |
Effects of (-)-sesamin on motor and memory deficits in an MPTP-lesioned mouse model of Parkinson's disease treated with l-DOPA.
Topics: Animals; Antiparkinson Agents; Avoidance Learning; Corpus Striatum; Dioxoles; Dopamine; Dose-Response Relationship, Drug; Levodopa; Lignans; Male; Memory; Memory Disorders; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Parkinsonian Disorders; RNA, Messenger; Substantia Nigra | 2016 |
Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway.
Topics: Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Chondrocytes; Dinoprostone; Dioxoles; Dose-Response Relationship, Drug; Heme Oxygenase-1; Humans; Interleukin-1beta; Lignans; Matrix Metalloproteinases, Secreted; Middle Aged; NF-E2-Related Factor 2; NF-KappaB Inhibitor alpha; Nitric Oxide; Osteoarthritis, Knee; Phosphorylation; RNA Interference; Signal Transduction; Transcription Factor RelA; Transfection | 2016 |
Absorption, distribution, metabolism, and excretion of [
Topics: Administration, Intravenous; Administration, Oral; Animals; Bile; Carbon Radioisotopes; Dioxoles; Feces; Lignans; Male; Rats, Sprague-Dawley; Tissue Distribution | 2017 |
Effects of (-)-Sesamin on Chronic Stress-Induced Anxiety Disorders in Mice.
Topics: Animals; Anti-Anxiety Agents; Antioxidants; Anxiety Disorders; Biogenic Monoamines; Brain; Chronic Disease; Corticosterone; Dioxoles; Lignans; Male; Mice; Mice, Inbred ICR; Stress, Psychological; Treatment Outcome | 2017 |
Physiological effects of γ-linolenic acid and sesamin on hepatic fatty acid synthesis and oxidation.
Topics: Acyl-CoA Oxidase; Animals; Dietary Fats, Unsaturated; Dietary Sucrose; Dietary Supplements; Dioxoles; Enoyl-CoA Hydratase; Fatty Acids; gamma-Linolenic Acid; Gene Expression Regulation, Enzymologic; Hyperlipidemias; Hypolipidemic Agents; Lignans; Linoleic Acids; Lipids; Liver; Male; Oenothera biennis; Oxidation-Reduction; Palm Oil; Peroxisomes; Plant Oils; Rats, Sprague-Dawley; Safflower Oil; Thiolester Hydrolases | 2017 |
In vivo modulation of LPS induced leukotrienes generation and oxidative stress by sesame lignans.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arachidonate 5-Lipoxygenase; Benzodioxoles; Biomarkers; Dietary Supplements; Dioxoles; Glutathione Transferase; Hepatitis; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lignans; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Oxidative Stress; Phenols; Phospholipases A2, Cytosolic; Rats, Wistar; Receptors, Leukotriene B4; Sesame Oil | 2017 |
Differential and directional estrogenic signaling pathways induced by enterolignans and their precursors.
Topics: 4-Butyrolactone; Cell Cycle; Dioxoles; Estrogens; Furans; Gene Expression Profiling; Humans; Lignans; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Signal Transduction | 2017 |
Sesamin imparts neuroprotection against intrastriatal 6-hydroxydopamine toxicity by inhibition of astroglial activation, apoptosis, and oxidative stress.
Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; Caspase 3; Dioxoles; Gliosis; Lignans; Male; Malondialdehyde; Neostriatum; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; Postural Balance; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Dietary Supplements; Dioxoles; Food Additives; gamma-Cyclodextrins; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Intrinsically Disordered Proteins; Lignans; Mutation; Oligonucleotide Array Sequence Analysis; RNA Interference; Sirtuins; Survival Analysis; TOR Serine-Threonine Kinases | 2018 |
Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction.
Topics: Administration, Oral; Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiomegaly; Diabetes Mellitus, Experimental; Dioxoles; Electrocardiography; Heart; Heart Rate; Lignans; Male; Myocardium; Rats; Rats, Sprague-Dawley; Streptozocin | 2017 |
Effects of asarinin on dopamine biosynthesis and 6-hydroxydopamine-induced cytotoxicity in PC12 cells.
Topics: Animals; Asarum; Cell Survival; Cells, Cultured; Dioxoles; Dopamine; Dose-Response Relationship, Drug; Lignans; Molecular Structure; Oxidopamine; PC12 Cells; Rats; Structure-Activity Relationship | 2017 |
Sesamin encouraging effects on chondrogenic differentiation of human amniotic fluid-derived mesenchymal stem cells.
Topics: Amniotic Fluid; Antioxidants; Cell Differentiation; Cell Survival; Chondrogenesis; Dioxoles; Flow Cytometry; Gene Expression Regulation, Developmental; Humans; Lignans; Mesenchymal Stem Cells | 2017 |
Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants.
Topics: Air Pollutants; Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 1; Dioxoles; Female; Flavanones; Lignans; Maternal Exposure; Mice; Microsomes, Liver; Pregnancy; Prenatal Exposure Delayed Effects; Quercetin | 2017 |
Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin-1beta in human chondrocytes.
Topics: Adult; Aggrecans; Cells, Cultured; Chondrocytes; Chondroitin Sulfate Proteoglycans; Dioxoles; Female; Glucuronosyltransferase; Humans; Interleukin-1beta; Lignans; Male; Middle Aged; Multifunctional Enzymes; N-Acetylgalactosaminyltransferases; Young Adult | 2017 |
Sesamin prevents apoptosis and inflammation after experimental myocardial infarction by JNK and NF-κB pathways.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Dioxoles; Disease Models, Animal; Humans; Lignans; Male; MAP Kinase Kinase 4; Mice; Myocardial Infarction; NF-kappa B; Plant Extracts; Sesamum; Signal Transduction | 2017 |
Sesamin alleviates blood-brain barrier disruption in mice with experimental traumatic brain injury.
Topics: Animals; Apoptosis; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Brain Injuries, Traumatic; Capillary Permeability; Caspase 3; Cell Line; Dioxoles; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Lignans; Male; Mice, Inbred C57BL; Neuroprotective Agents; Occludin; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Time Factors; Zonula Occludens-1 Protein | 2017 |
Sesamin protects SH-SY5Y cells against mechanical stretch injury and promoting cell survival.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Survival; Dioxoles; DNA Fragmentation; Humans; Lignans; MAP Kinase Kinase 4; Matrix Metalloproteinase 9; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2017 |
Mechanisms of chromosomal aberrations induced by sesamin metabolites in Chinese hamster lung cells.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Chromosome Aberrations; Cricetinae; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Glutathione; Hep G2 Cells; Humans; Lignans; Liver; Liver Extracts; Lung | 2017 |
Inhibitory effects of sesamin on human osteoclastogenesis.
Topics: Bone Marrow Cells; Bone Resorption; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dioxoles; Gene Expression; Healthy Volunteers; Humans; Lignans; Macrophage Colony-Stimulating Factor; Osteoclasts; Osteogenesis; RANK Ligand | 2017 |
A new pair of enantiomeric lignans from the fruits of Morinda citrifolia and their absolute configuration.
Topics: Animals; Cell Line; Circular Dichroism; Dioxoles; Fruit; Inhibitory Concentration 50; Lignans; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Morinda; Nitric Oxide; Stereoisomerism | 2018 |
Effects of sesamin on primary human synovial fibroblasts and SW982 cell line induced by tumor necrosis factor-alpha as a synovitis-like model.
Topics: Arthritis, Rheumatoid; Cell Line; Cytokines; Dioxoles; Fibroblasts; Humans; Lignans; Models, Biological; Signal Transduction; Synovial Membrane; Synovitis; Tumor Necrosis Factor-alpha | 2017 |
Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway.
Topics: Animals; Antioxidants; Cardiomegaly; Dioxoles; Fibrosis; Heart; Inflammation; Lignans; Male; MAP Kinase Signaling System; Mice; Myocardium; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Sirtuin 3 | 2017 |
Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame.
Topics: Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Humans; Lignans; Molecular Structure; Mutation; Oxidation-Reduction; Oxidative Stress; Phylogeny; Plant Proteins; Sesamum | 2017 |
7-Hydroxylation of warfarin is strongly inhibited by sesamin, but not by episesamin, caffeic and ferulic acids in human hepatic microsomes.
Topics: Anticoagulants; Caffeic Acids; Coumaric Acids; Dietary Supplements; Dioxoles; Female; Food; Humans; Hydroxylation; Inhibitory Concentration 50; Kinetics; Lignans; Male; Microsomes, Liver; Warfarin | 2018 |
Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker β-catenin: an in silico study.
Topics: beta Catenin; Binding Sites; Colonic Neoplasms; Computer Simulation; Dioxoles; Humans; Lignans; Models, Molecular; Molecular Docking Simulation; Protein Binding; Protein Conformation; Transcription Factor 4 | 2019 |
[Metabolism of Sesamin and Drug-Sesamin Interaction].
Topics: Animals; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Diclofenac; Dioxoles; Drug Interactions; Humans; Lignans; Rats | 2018 |
Sesamin induces ER stress-mediated apoptosis and activates autophagy in cervical cancer cells.
Topics: Apoptosis; Autophagy; Cell Movement; Cell Proliferation; Dioxoles; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Lignans; Neoplasm Proteins; Uterine Cervical Neoplasms | 2018 |
Sesamin from Cuscuta palaestina natural plant extracts: Directions for new prospective applications.
Topics: Calibration; Cuscuta; Dioxoles; Gas Chromatography-Mass Spectrometry; Lignans | 2018 |
The Use of a Molybdenum Polyoxometalated Compound to Increase the Amount of Extractives from Wood Wastes.
Topics: Dioxoles; Gas Chromatography-Mass Spectrometry; Industrial Waste; Larix; Lignans; Molybdenum; Phenols; Phosphoric Acids; Plant Extracts; Quercus; Wood | 2018 |
Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans.
Topics: Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Benzodioxoles; Caenorhabditis elegans; Chemotaxis; Dioxoles; Lignans; Longevity; Neurons; Paralysis; Phenols; Protein Multimerization; Transgenes | 2018 |
[Sesamin Preconditioning Attenuates Myocardial Ischemia Reperfusion Injury in Rats Through Activation of Akt/eNOS Signaling Pathway].
Topics: Animals; Apoptosis; Dioxoles; Heart; L-Lactate Dehydrogenase; Lignans; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Suppression of cyclooxygenase 2 increases chemosensitivity to sesamin through the Akt‑PI3K signaling pathway in lung cancer cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dioxoles; Down-Regulation; Humans; Lignans; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2019 |
Gallic acid as main product in the water extractives of
Topics: Chloroform; Dioxoles; Gallic Acid; Lignans; Mannose; Plant Extracts; Quercus; Ribose; Solubility; Water; Wood | 2019 |
(+)-Sesamin attenuates chronic unpredictable mild stress-induced depressive-like behaviors and memory deficits via suppression of neuroinflammation.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Cytokines; Depression; Dietary Supplements; Dioxoles; Disease Models, Animal; Inflammation; Lignans; Male; Maze Learning; Memory Disorders; Mice, Inbred Strains; Nerve Tissue Proteins; Norepinephrine; Serotonin | 2019 |
Protective effect of sesamin in lipopolysaccharide-induced mouse model of acute kidney injury via attenuation of oxidative stress, inflammation, and apoptosis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cytokines; Dioxoles; Disease Models, Animal; Inflammation; Kidney Function Tests; Lignans; Lipopolysaccharides; Male; Mice, Inbred C57BL; Oxidative Stress | 2018 |
Comparative Transcriptomics Analysis for Gene Mining and Identification of a Cinnamyl Alcohol Dehydrogenase Involved in Methyleugenol Biosynthesis from
Topics: Alcohol Oxidoreductases; Asarum; Cloning, Molecular; Dioxoles; Eugenol; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Lignans; Metabolic Networks and Pathways; Phylogeny; Plant Leaves; Plant Proteins; Plant Roots; Recombinant Proteins; Rhizome | 2018 |
Sesame Extract Attenuates the Degradation of Collagen and Elastin Fibers in the Vascular Walls of Nicotine-administered Mice.
Topics: Animals; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Body Weight; Collagen; Dioxoles; Eating; Elastin; Lignans; Male; Matrix Metalloproteinase 12; Mice, Inbred C57BL; Nicotine; Oxidative Stress; Plant Extracts; Sesamum | 2019 |
High temperature treatment allows the detection of episesamin in paulownia wood extractives.
Topics: Chemical Fractionation; Chloroform; Chromatography, High Pressure Liquid; Color; Dioxoles; Gas Chromatography-Mass Spectrometry; Lamiales; Lignans; Lignin; Plant Extracts; Temperature; Wood | 2020 |
Absolute configuration determination of asarinin by synchrotron radiation with crystalline sponge method.
Topics: Asarum; Biological Products; China; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Phytochemicals; Synchrotrons | 2019 |
Chiral resolution and bioactivity of enantiomeric furofuran lignans from
Topics: Amyloid beta-Peptides; Dioxoles; Furans; Juglans; Lignans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Optical Rotation; Peptide Fragments; Stereoisomerism | 2020 |
Sesamin suppresses aging phenotypes in adult muscular and nervous systems and intestines in a Drosophila senescence-accelerated model.
Topics: Aging; Animals; Antioxidants; Cells, Cultured; Chromatography, Liquid; Dioxoles; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Intestines; Lignans; Longevity; Muscles; Nervous System; Phenotype; Superoxide Dismutase; Tandem Mass Spectrometry | 2019 |
Quantification of bioactive lignans in sesame seeds using HPTLC densitometry: Comparative evaluation by HPLC-PDA.
Topics: Chromatography, High Pressure Liquid; Densitometry; Dioxoles; Lignans; Seeds; Sesamum | 2019 |
Sesamin Catechol Glucuronides Exert Anti-inflammatory Effects by Suppressing Interferon β and Inducible Nitric Oxide Synthase Expression through Deconjugation in Macrophage-like J774.1 Cells.
Topics: Animals; Anti-Inflammatory Agents; Catechol O-Methyltransferase; Catechols; Cell Line; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronidase; Glucuronides; Interferon-beta; Lignans; Macrophages; Mice; Molecular Structure; Nitric Oxide Synthase Type II | 2019 |
Drought stress influenced sesamin and sesamolin content and polyphenolic components in sesame (Sesamum indicum L.) populations with contrasting seed coat colors.
Topics: Antioxidants; Dioxoles; Droughts; Flavonoids; Free Radical Scavengers; Genotype; Lignans; Phenols; Pigments, Biological; Polyphenols; Seeds; Sesamum | 2019 |
Using Turmeric Oil as a Solvent Improves the Distribution of Sesamin-Sesamolin in the Serum and Brain of Mice.
Topics: Administration, Oral; Animals; Biological Availability; Brain; Dioxoles; Lignans; Male; Mice; Molecular Conformation; Oils, Volatile; Solubility; Solvents | 2019 |
Amelioration of CIA by Asarinin Is Associated to a Downregulation of TLR9/NF-κB and Regulation of Th1/Th2/Treg Expression.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cytokines; Dioxoles; Down-Regulation; Knee Joint; Lignans; Male; Mice, Inbred DBA; NF-kappa B; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells; Toll-Like Receptor 9 | 2019 |
Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats.
Topics: Animals; Antioxidants; Apoptosis; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus, Experimental; Dioxoles; Glutathione Peroxidase; Hippocampus; Insulin; Lignans; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
Identification of a binding protein for sesamin and characterization of its roles in plant growth.
Topics: Arabidopsis; Carrier Proteins; Dioxoles; Germination; Lignans; Plant Development; Plant Proteins; Plants, Genetically Modified; Proton Magnetic Resonance Spectroscopy; Seeds | 2019 |
Sesamin Promotes Osteoblastic Differentiation and Protects Rats from Osteoporosis.
Topics: Alkaline Phosphatase; Animals; beta Catenin; Bone and Bones; Cell Differentiation; Cell Proliferation; China; Collagen Type I; Dioxoles; Female; Lignans; Mesenchymal Stem Cells; Osteoblasts; Osteocalcin; Osteogenesis; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway | 2019 |
Intradiscal injection of sesamin protects from lesion-induced degeneration.
Topics: Animals; Dioxoles; Disease Models, Animal; DNA; Extracellular Matrix; Gene Expression Regulation; Intervertebral Disc; Intervertebral Disc Degeneration; Lignans; Magnetic Resonance Imaging; Nucleus Pulposus; Proteoglycans; Rats, Sprague-Dawley; RNA, Messenger | 2020 |
Sesamin Enhances Nrf2-Mediated Protective Defense against Oxidative Stress and Inflammation in Colitis via AKT and ERK Activation.
Topics: Animals; Antioxidants; Caco-2 Cells; Colitis; Dioxoles; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Lignans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Transcriptional Activation | 2019 |
Protective Effects of Sesamin against UVB-Induced Skin Inflammation and Photodamage In Vitro and In Vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Dermatitis; Dioxoles; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Humans; Hyperplasia; Lignans; Matrix Metalloproteinases; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Skin; Skin Aging; Tissue Inhibitor of Metalloproteinase-1; Ultraviolet Rays | 2019 |
Quantitative Analysis of Twelve Active Components Combined With Chromatographic Fingerprint for Comprehensive Evaluation of Qinma Prescription by Ultra-Performance Liquid Chromatography Coupled With Diode Array Detection.
Topics: Catechols; Chemical Fractionation; Chromatography, High Pressure Liquid; Dioxoles; Drugs, Chinese Herbal; Fatty Alcohols; Flavonoids; Gallic Acid; Lignans; Limit of Detection; Linear Models; Reproducibility of Results | 2019 |
Glycoside-specific glycosyltransferases catalyze regio-selective sequential glucosylations for a sesame lignan, sesaminol triglucoside.
Topics: Biosynthetic Pathways; Catalysis; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Glucosides; Glucosyltransferases; Glycosyltransferases; Lignans; Phylogeny; Plant Proteins; Seeds; Sesamum | 2020 |
Supplementation of Sesamin Alleviates Stress-Induced Behavioral and Psychological Disorders via Reshaping the Gut Microbiota Structure.
Topics: Animals; Bacteria; Behavior; Depression; Dietary Supplements; Dioxoles; Gastrointestinal Microbiome; Humans; Lignans; Male; Mice; Oxidative Stress; Plant Extracts; Seeds; Sesamum; Stress, Psychological | 2019 |
Rapid and nondestructive determination of sesamin and sesamolin in Chinese sesames by near-infrared spectroscopy coupling with chemometric method.
Topics: China; Dioxoles; Lignans; Sesamum; Spectroscopy, Near-Infrared | 2020 |
Sesamin suppresses NSCLC cell proliferation and induces apoptosis via Akt/p53 pathway.
Topics: Animals; Apoptosis; Benzothiazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chromones; Dioxoles; Female; G1 Phase Cell Cycle Checkpoints; Humans; Lignans; Lung Neoplasms; Mice; Morpholines; Proto-Oncogene Proteins c-akt; Signal Transduction; Toluene; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2020 |
Administration timing and duration-dependent effects of sesamin isomers on lipid metabolism in rats.
Topics: Animals; Circadian Rhythm; Dioxoles; Lignans; Lipid Metabolism; Liver; Rats; Rats, Sprague-Dawley | 2020 |
Ameliorative effect of sesamin in cisplatin-induced nephrotoxicity in rats by suppressing inflammation, oxidative/nitrosative stress, and cellular damage.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Dioxoles; Drug Evaluation, Preclinical; Kidney; Kidney Diseases; Lignans; Male; Phytotherapy; Plant Extracts; Rats, Wistar; Sesamum | 2020 |
Sesamin promotes angiogenesis and accelerates wound healing in rats via alleviates TBHP-induced apoptosis in human umbilical vein endothelial cells.
Topics: Angiogenesis Inducing Agents; Animals; Apoptosis; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Dioxoles; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Signal Transduction; tert-Butylhydroperoxide; Wound Healing | 2020 |
Ameliorating effect of sesamin on insulin resistance of hepatic L02 cells induced by high glucose/high insulin.
Topics: Antigens, CD; Cell Line; Chromatography, High Pressure Liquid; Dioxoles; Glucose; Glucose Transporter Type 4; Glycogen; Hepatocytes; Humans; Immunoblotting; Insulin Receptor Substrate Proteins; Insulin Resistance; Lignans; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction | 2019 |
(-)-Asarinin inhibits mast cells activation as a Src family kinase inhibitor.
Topics: Animals; Dioxoles; Humans; Lignans; Mast Cells; Mice; src-Family Kinases | 2020 |
A comparative study on root and bark extracts of Eleutherococcus senticosus and their effects on human macrophages.
Topics: Anti-Inflammatory Agents; Cell Polarity; Coumarins; Dioxoles; Eleutherococcus; Glucosides; Humans; Lignans; Macrophages; NF-kappa B; Phenylpropionates; Plant Bark; Plant Extracts; Plant Roots; Plants, Medicinal | 2020 |
Sesamin Induces Endothelial Nitric Oxide Synthase Activation via Transient Receptor Potential Vanilloid Type 1.
Topics: AMP-Activated Protein Kinases; Dioxoles; Endothelial Cells; Lignans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt | 2020 |
A Network Pharmacology Approach to Estimate the Active Ingredients and Potential Targets of Cuscutae semen in the Treatment of Osteoporosis.
Topics: Catalytic Domain; Cyclins; Dioxoles; Drugs, Chinese Herbal; ErbB Receptors; Gene Ontology; Humans; Interleukin-6; Lignans; Mitogen-Activated Protein Kinase 8; Molecular Docking Simulation; Molecular Targeted Therapy; Osteoporosis; Protein Interaction Maps; Thermodynamics; Vascular Endothelial Growth Factor A | 2020 |
Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame.
Topics: Anticarcinogenic Agents; Antioxidants; Benzodioxoles; Coumaric Acids; Digestion; Dioxoles; Flavonoids; Gallic Acid; Hydroxybenzoates; Lignans; Parabens; Phenol; Phenols; Plant Extracts; Principal Component Analysis; Propionates; Quercetin; Seeds; Sesamum | 2020 |
Topics: Animals; Cell Line; Dioxoles; Gene Expression; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Larva; Lignans; Mice; Sesame Oil; Zebrafish | 2020 |
In Vitro Inhibitory Effects of Sesamin on CYP4F2 Activity.
Topics: Animals; Baculoviridae; Cytochrome P450 Family 4; Dioxoles; Insecta; Lignans; Microsomes; NADP; Recombinant Proteins | 2020 |
Simultaneous and rapid determination of sesamin and sesamolin in sesame oils using excitation-emission matrix fluorescence coupled with self-weighted alternating trilinear decomposition.
Topics: Dioxoles; Fluorescence; Lignans; Sesame Oil; Sesamum; Spectrometry, Fluorescence | 2020 |
Formation of Samin Diastereomers by Acid-Catalyzed Transformation of Sesamolin with Hydrogen Peroxide.
Topics: Acids; Catalysis; Dioxoles; Hydrogen Peroxide; Lignans; Molecular Structure; Seeds; Sesamum; Stereoisomerism | 2020 |
Antimetastatic Effects of Sesamin on Human Head and Neck Squamous Cell Carcinoma through Regulation of Matrix Metalloproteinase-2.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Dioxoles; Head and Neck Neoplasms; Humans; Lignans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Squamous Cell Carcinoma of Head and Neck; Zanthoxylum | 2020 |
Sesame lignans suppress age-related disorders of the kidney in mice.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Diet; Dioxoles; Kidney Diseases; Lignans; Male; Mice; Mice, Inbred C57BL; Sesamum | 2020 |
Identification of a natural compound, sesamin, as a novel TRPM8 antagonist with inhibitory effects on prostate adenocarcinoma.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Dioxoles; HEK293 Cells; Humans; Lignans; Male; Molecular Docking Simulation; Molecular Structure; Prostatic Neoplasms; TRPM Cation Channels | 2020 |
Characterization and Oxidative Stability of Cold-pressed Sesame Oil Microcapsules Prepared by Complex Coacervation.
Topics: Capsules; Chemical Phenomena; Dioxoles; Drug Compounding; Fatty Acids; Food Storage; Food Technology; Gelatin; Gum Arabic; Lignans; Molecular Imaging; Oxidation-Reduction; Particle Size; Sesame Oil; Static Electricity; Vitamin E | 2020 |
Inhibitory effects of sesamin on CYP2C9-dependent 7-hydroxylation of S-warfarin.
Topics: Cytochrome P-450 CYP2C9; Dioxoles; Enzyme Inhibitors; Humans; Hydroxylation; Kinetics; Lignans; Microsomes, Liver; Molecular Structure; Warfarin | 2020 |
Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na
Topics: Adenoma; Animals; Antioxidants; Dioxoles; Ion Channel Gating; Lignans; Pituitary Neoplasms; Potassium Channels, Voltage-Gated; Rats; Sesame Oil; Tumor Cells, Cultured; Voltage-Gated Sodium Channels | 2020 |
Inhibition of programmed death ligand 1 (PD-L1) expression in breast cancer cells by sesamin.
Topics: Adenocarcinoma; B7-H1 Antigen; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Dioxoles; Female; Humans; Janus Kinases; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MCF-7 Cells; NF-kappa B; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT Transcription Factors; Triple Negative Breast Neoplasms; Up-Regulation | 2020 |
Sesamin attenuates histological alterations, oxidative stress and expressions of immune-related genes in liver of zebrafish (Danio rerio) exposed to fluoride.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytokines; Dioxoles; Fluorides; Gene Expression Regulation; Lignans; Liver; Male; Oxidative Stress; Protective Agents; Water Pollutants, Chemical; Zebrafish | 2020 |
Molecular modelling investigation for drugs and nutraceuticals against protease of SARS-CoV-2.
Topics: Antiviral Agents; Binding Sites; Coronavirus 3C Proteases; Cysteine Endopeptidases; Dietary Supplements; Dioxoles; Diterpenes; Hydrogen Bonding; Lignans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protease Inhibitors; Protein Conformation; Viral Nonstructural Proteins | 2020 |
A stepwise integrated multi-system to screen quality markers of Chinese classic prescription Qingzao Jiufei decoction on the treatment of acute lung injury by combining 'network pharmacology-metabolomics-PK/PD modeling'.
Topics: Acute Lung Injury; Administration, Oral; Amygdalin; Animals; Biological Availability; Biomarkers, Pharmacological; Chalcone; Chlorogenic Acid; Dioxoles; Drugs, Chinese Herbal; Flavanones; Glucosides; Lignans; Male; Metabolomics; Rats, Wistar; Triterpenes; Ursolic Acid | 2020 |
Sesamin attenuates intestinal injury in sepsis via the HMGB1/TLR4/IL-33 signalling pathway.
Topics: Animals; Bacteria; Cell Line; Cytokines; Dioxoles; Disease Models, Animal; Epithelial Cells; HMGB1 Protein; Humans; Inflammation; Interleukin-33; Intestinal Mucosa; Lignans; Male; Mice; Mice, Inbred BALB C; Occludin; Sepsis; Signal Transduction; Toll-Like Receptor 4; Zonula Occludens-1 Protein | 2020 |
(+)-Sesamin-oxidising CYP92B14 shapes specialised lignan metabolism in sesame.
Topics: Amino Acid Sequence; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Glucosides; Lignans; Models, Molecular; Oxidation-Reduction; Phylogeny; Plant Proteins; Seeds; Sequence Alignment; Sesamum | 2020 |
Simultaneous determination of asarinin, β-eudesmol, and wogonin in rats using ultraperformance liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies following administration of standards and Gumiganghwal-tang.
Topics: Animals; Chromatography, High Pressure Liquid; Dioxoles; Flavanones; Lignans; Linear Models; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes, Eudesmane; Tandem Mass Spectrometry | 2021 |
Sesamin attenuates carrageenan-induced lung inflammation through upregulation of A20 and TAX1BP1 in rats.
Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; Biomarkers; Carrageenan; Dioxoles; Gene Expression Regulation; Inflammation; Lignans; Lung Diseases; Neoplasm Proteins; Neutrophils; NF-kappa B; Pleural Effusion; Rats; Tumor Necrosis Factor alpha-Induced Protein 3; Up-Regulation | 2020 |
Inhibitory Effectiveness of Gomisin A, a Dibenzocyclooctadiene Lignan Isolated from
Topics: Animals; Cell Line; Cyclooctanes; Dioxoles; Ion Transport; Kinetics; Lignans; Potassium Channels, Voltage-Gated; Rats; Schisandra; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2020 |
Full-length transcriptome analysis and identification of genes involved in asarinin and aristolochic acid biosynthesis in medicinal plant
Topics: Alternative Splicing; Anticholesteremic Agents; Antihypertensive Agents; Antioxidants; Aristolochic Acids; Asarum; Biosynthetic Pathways; Dioxoles; Gene Expression Profiling; Gene Expression Regulation, Plant; Lignans; Microsatellite Repeats; Plant Breeding; Plant Leaves; Plant Roots; Plants, Medicinal; RNA, Long Noncoding; Transcriptome | 2021 |
Sesamin alleviates diabetes-associated behavioral deficits in rats: The role of inflammatory and neurotrophic factors.
Topics: Animals; Antioxidants; Anxiety; Cerebral Cortex; Depression; Diabetes Mellitus, Experimental; Dioxoles; Disease Models, Animal; Hippocampus; Inflammation; Lignans; Male; Maze Learning; Memory Disorders; Nerve Growth Factors; Neuroprotective Agents; Rats | 2021 |
Sesamin protects against DSS-induced colitis in mice by inhibiting NF-κB and MAPK signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Dextran Sulfate; Dioxoles; Lignans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Protective Agents | 2021 |
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclin D1; Dioxoles; Dose-Response Relationship, Drug; Humans; JNK Mitogen-Activated Protein Kinases; Lignans; Mice; Mice, Inbred BALB C; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Time Factors; Up-Regulation | 2021 |
Promotive effects of sesamin on proliferation and adhesion of intestinal probiotics and its mechanism of action.
Topics: Animals; Bacterial Adhesion; Bacterial Proteins; Bifidobacterium bifidum; Cell Line; Dioxoles; Dose-Response Relationship, Drug; Epithelial Cells; Feces; Gastrointestinal Microbiome; Gene Expression Regulation, Bacterial; Humans; Intestinal Mucosa; Lactobacillus acidophilus; Lignans; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2021 |
Ptehoosines A and B: Two new sesamin-type sesquilignans with antiangiogenic activity from Pterocephalus hookeri (C.B. Clarke) Höeck.
Topics: Angiogenesis Inhibitors; Animals; Caprifoliaceae; Cell Cycle Checkpoints; Dioxoles; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Medicine, Tibetan Traditional; Molecular Structure; Phytochemicals; Tibet; Zebrafish | 2021 |
Inhibitory effect of sesamin on ivabradine metabolism in rats.
Topics: Administration, Oral; Animals; Area Under Curve; Cardiovascular Agents; Chromatography, High Pressure Liquid; Dioxoles; Ivabradine; Lignans; Male; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2020 |
Sesamin suppresses advanced glycation end products induced microglial reactivity using BV2 microglial cell line as a model.
Topics: Animals; Antioxidants; Cell Line; Dioxoles; Glycation End Products, Advanced; Lignans; Mice; Microglia; Neuroprotective Agents; NF-kappa B; Phosphorylation; Signal Transduction | 2021 |
Sesamin exerts anti-tumor activity in esophageal squamous cell carcinoma via inhibition of TRIM44 and NF-κB signaling.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dioxoles; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Intracellular Signaling Peptides and Proteins; Lignans; Mice; Mice, Nude; NF-kappa B; Signal Transduction; Transplantation, Heterologous; Tripartite Motif Proteins | 2022 |
A novel study on the immunomodulatory effect of umbilical cord derived mesenchymal stem cells pretreated with traditional Chinese medicine Asarinin.
Topics: Animals; Cells, Cultured; Cytokines; Dioxoles; Disease Models, Animal; Drugs, Chinese Herbal; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Lignans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Primary Cell Culture; Transplantation, Homologous; Umbilical Cord | 2021 |
Sesamin promotes apoptosis and pyroptosis via autophagy to enhance antitumour effects on murine T-cell lymphoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Dioxoles; Disease Models, Animal; Female; Lignans; Lymphoma, T-Cell; Mice, Inbred BALB C; Phytotherapy; Pyroptosis; Stimulation, Chemical | 2021 |
Topics: Acute Lung Injury; Adherens Junctions; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; beta Catenin; Brain Ischemia; Cadherins; Carcinogenesis; Catalysis; Cell Line; Cells, Cultured; Curcuma; Curcumin; Dioxoles; Disease Models, Animal; Endothelial Cells; Epithelial Cells; Heme Oxygenase (Decyclizing); Humans; Inflammasomes; Intestinal Diseases; Intestinal Mucosa; Ischemic Stroke; Kidney Neoplasms; Lignans; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NAD(P)H Dehydrogenase (Quinone); Nanostructures; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; Pneumonia; PPAR gamma; Proto-Oncogene Proteins c-akt; Pyroptosis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Sepsis; Sesamum; Signal Transduction; Silybin; Silybum marianum; Silymarin; Sirtuin 3; Titanium; Transfection; Treatment Outcome; White Matter | 2021 |
Sesamin attenuates PM
Topics: Animals; Antioxidants; Cardiovascular Diseases; Dioxoles; Disease Models, Animal; Ferroptosis; Lignans; Particulate Matter; Rats; Rats, Sprague-Dawley | 2021 |
Route of intracellular uptake and cytotoxicity of sesamol, sesamin, and sesamolin in human melanoma SK-MEL-2 cells.
Topics: Benzodioxoles; Dioxoles; Humans; Lignans; Melanoma; Phenols | 2022 |
DANCR Mediates the Rescuing Effects of Sesamin on Postmenopausal Osteoporosis Treatment via Orchestrating Osteogenesis and Osteoclastogenesis.
Topics: Animals; beta Catenin; Bone Resorption; Cell Differentiation; Dioxoles; Female; HEK293 Cells; Humans; Lignans; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis, Postmenopausal; RANK Ligand; RAW 264.7 Cells; RNA, Long Noncoding; Wnt Signaling Pathway | 2021 |
(+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis.
Topics: Benzodioxoles; Dioxoles; Enzyme Inhibitors; Gastrointestinal Microbiome; Kinetics; Lignans; Molecular Docking Simulation; Phenols; Renal Insufficiency, Chronic; Sesamum; Tryptophanase | 2022 |
Sesamin suppresses high glucose-induced microglial inflammation in the retina in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dioxoles; Inflammation; Lignans; Male; Mice; Microglia | 2022 |
Sesamin and Hepatic Metabolites Derived from Sesamin and Episesamin Antagonize Farnesoid X Receptor and Reduce the Expression of Gluconeogenesis-Related Genes.
Topics: Animals; Dioxoles; Gluconeogenesis; Lignans; Liver; Mice | 2022 |
Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells.
Topics: Benzodioxoles; Cholesterol; Dioxoles; Hep G2 Cells; Humans; Lignans; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phenols; Sesame Oil; Sesamum | 2022 |
Sesamin Alleviates Asthma Airway Inflammation by Regulating Mitophagy and Mitochondrial Apoptosis.
Topics: Animals; Apoptosis; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dioxoles; Humans; Inflammation; Interleukin-4; Lignans; Lung; Mice; Mitochondria; Mitophagy; Protein Kinases; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 2022 |
Sesamin: Insights into its protective effects against lead-induced learning and memory deficits in rats.
Topics: Animals; Dioxoles; Gamma Rhythm; Hippocampus; Lead; Lignans; Maze Learning; Memory Disorders; Rats | 2022 |
Sesamin Promotes Osteoporotic Fracture Healing by Activating Chondrogenesis and Angiogenesis Pathways.
Topics: Animals; Chondrogenesis; Dioxoles; Female; Fracture Healing; Humans; Lignans; Mice; Osteoporotic Fractures; Rats; Rats, Sprague-Dawley | 2022 |
Alleviation of cognitive deficits via upregulation of chondroitin sulfate biosynthesis by lignan sesamin in a mouse model of neuroinflammation.
Topics: Animals; Chondroitin Sulfate Proteoglycans; Chondroitin Sulfates; Cognition; Dioxoles; Disease Models, Animal; Hippocampus; Lignans; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Up-Regulation | 2022 |
Sesamin protects against neurotoxicity via inhibition of microglial activation under high glucose circumstances through modulating p38 and JNK signaling pathways.
Topics: Animals; Culture Media, Conditioned; Dioxoles; Glucose; Lignans; MAP Kinase Signaling System; Mice; Microglia; Neurotoxicity Syndromes; Rats | 2022 |
Sesamin Ameliorates Fine Particulate Matter (PM
Topics: Animals; Apoptosis; Autophagy; Dioxoles; Inflammation; Lignans; Lung; Lung Injury; Oxidative Stress; Particulate Matter; Rats; Rats, Sprague-Dawley | 2022 |
Sesamin inhibits hypoxia-stimulated angiogenesis
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Dioxoles; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lignans; Mice; Mice, Nude; Neovascularization, Pathologic; NF-kappa B; Signal Transduction; Vascular Endothelial Growth Factor A | 2022 |
The Protective Effects of Sesamin against Cyclophosphamide-Induced Nephrotoxicity through Modulation of Oxidative Stress, Inflammatory-Cytokines and Apoptosis in Rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Caspase 3; Creatinine; Cyclophosphamide; Cytokines; Dioxoles; Kidney; Lignans; Malondialdehyde; Oxidative Stress; Rats; Renal Insufficiency; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Uric Acid | 2022 |
Sesamin Attenuates Obesity-Associated Nonalcoholic Steatohepatitis in High-Fat and High-Fructose Diet-Fed Mice.
Topics: Animals; Diet; Diet, High-Fat; Dioxoles; Fructose; Lignans; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Protein Serine-Threonine Kinases | 2023 |
Sesamin Metabolites Suppress the Induction of Cellular Senescence.
Topics: Cellular Senescence; Humans; Lignans; Liver; Reactive Oxygen Species | 2023 |
Sesamin lacks zebrafish embryotoxicity but exhibits evidence of anti-angiogenesis, anti-oxidant and anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Embryo, Nonmammalian; Inflammation; Lignans; Oxidative Stress; Reactive Oxygen Species; Zebrafish | 2023 |
Evaluation of Steaming and Drying of Black Sesame Seeds for Nine Cycles Using Grey-Correlation Analysis Based on Variation-Coefficient Weight.
Topics: Lignans; Melanins; Seeds; Sesamum; Steam | 2023 |
Sesamin ameliorates lipotoxicity and lipid accumulation through the activation of the estrogen receptor alpha signaling pathway.
Topics: AMP-Activated Protein Kinases; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Estrogen Receptor alpha; Hep G2 Cells; Humans; Lignans; Lipid Metabolism; Liver; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Palmitates; Signal Transduction; Sterol Regulatory Element Binding Protein 1 | 2023 |
Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.
Topics: Animals; Bleomycin; Idiopathic Pulmonary Fibrosis; Lignans; Mice; PPAR gamma | 2023 |
Effects of Combining Docosahexaenoic Acid and Eicosapentaenoic Acid with Sesame Lignan on Vascular Endothelial Function.
Topics: Docosahexaenoic Acids; Eicosapentaenoic Acid; Human Umbilical Vein Endothelial Cells; Humans; Lignans; Sesamum | 2023 |
Sesamin: A Promising Therapeutic Agent for Ameliorating Symptoms of Diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Dioxoles; Glycated Hemoglobin; Insulin; Lignans; Plant Extracts; Rats; Rats, Wistar | 2023 |