Page last updated: 2024-08-24

sertindole and olanzapine

sertindole has been researched along with olanzapine in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	24 (34.29)	18.2507
2000's	30 (42.86)	29.6817
2010's	14 (20.00)	24.3611
2020's	2 (2.86)	2.80

Authors

Authors	Studies
De Loore, K; Gommeren, W; Janssen, PF; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van Gompel, P	1
Arnt, J; Skarsfeldt, T	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Grinde, E; Herrick-Davis, K; Teitler, M	1
Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
Keserü, GM	1
Wermuth, CG	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Jia, L; Sun, H	1
Giordanetto, F; Leach, AG; Zachariae, U	1
Jensen, AA; Kehler, J; Krogsgaard-Larsen, N	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Sen, S; Sinha, N	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A	1
Cools, AR; Ellenbroek, BA; Prinssen, EP	1
Borison, RL	1
Lahti, AC; Tamminga, CA	1
Casey, DE	1
Tamminga, CA	1
Davidson, M; Levy, A; Weizer, M	1
Schooler, NR	1
Daniel, DG; Whitcomb, SR	1
Pollock, BG; Sweet, RA	1
Altshuler, LL; Corá-Locatelli, G; Denicoff, K; Dunn, RT; Frye, MA; Ketter, TA; Kimbrell, TA; Post, RM	1
Gao, XM; Sakai, K; Tamminga, CA	1
Depoortere, R; Perrault, G; Sanger, DJ	1
Sams-Dodd, F	1
Abraham, D; Kissling, W; Leucht, S; Pitschel-Walz, G	1
Kane, JM	1
Berisford, MA; Goldstein, D; Kysar, L; Marder, SR; Mintz, J; Pashdag, J; Wirshing, DA; Wirshing, WC	1
Baker, GB; Chue, PS; Prior, TI; Tibbo, P	1
Bayle, FJ; Ghaoui, S; Olie, JP	1
Azorin, JM; Hale, A; Kasper, S; Möller, HJ	1
Kulkarni, SK; Ninan, I	1
Philibin, SD; Porter, JH; Vann, RE; Varvel, SA; Wise, LE	2
Möller, HJ	1
McAskill, R; Taylor, DM	1
Marcus, MM; Nomikos, GG; Svensson, TH	1
Acton, PD; Bigliani, V; Ell, PJ; Gacinovic, S; Kerwin, RW; Mulligan, RS; Ohlsen, RI; Pike, VW; Pilowsky, LS	1
Bebbington, P; Freemantle, N; Geddes, J; Harrison, P	1
Kapur, S; Remington, G	1
Gao, XM; Hashimoto, T; Sakai, K; Tamminga, CA	1
Agelink, MW; Klieser, E; Linka, T; Lukas, K; Majewski, T; Ullrich, H; Wurthmann, C	1
Hilger, E; Kasper, S	1
Heeley, EL; Pickering, RM; Shakir, SA; Wilton, LV	1
Revicki, DA	1
Andersen, MP; Pouzet, B	1
Danileviciūte, V	1
Hedges, D; Jeppson, K; Whitehead, P	1
Bryois, Ch; Sahli, Ch	1
Beasley, CM; Carlson, C; Crumb, WJ; Ekins, S; Sarazan, RD; Wikel, JH; Wrighton, SA	1
Arnt, J; Didriksen, M; Kreilgaard, M	1
Brennum, LT; Kreilgaard, M; Olsen, CK	1
Bate, A; Hägg, S; Spigset, O; Stahl, M	1
Davis, JM; Hunger, H; Kissling, W; Komossa, K; Leucht, S; Lobos, CA; Rummel-Kluge, C; Schmid, F; Schwarz, S	1
Hunger, H; Kissling, W; Komossa, K; Leucht, S; Rummel-Kluge, C; Schmid, F; Schwarz, S	1
Akar, FY; Celikyurt, IK; Erden, F; Mutlu, O; Ulak, G	1
Friis, S; Haahr, U; Johannessen, JO; Larsen, TK; McGlashan, TH; Melle, I; Opjordsmoen, S; Rund, BR; Simonsen, E; Vaglum, P	1
Akar, FY; Celikyurt, IK; Erden, F; Mutlu, O; Tanyeri, P; Ulak, G	1
Eberhard, J; Fors, BM; Hansen, K; Lindström, E; Sapin, C	1
Grabski, B; Siwek, M; Woroń, J	1
Cai, ZJ; Hwang, JY; Kwon, JS; Mittoux, A; Ong, A; Su, TP	1
Blagojević, D; Lečić-Toševski, D; Miljević, Č; Niketić, V; Nikolić, M; Nikolić-Kokić, A; Spasić, MB	1
Davis, JM; Leucht, S; Smith, RC	1
Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S	1
Cvijetić, I; Gligorijević, N; Kokić, AN; Mijatović, A; Miljević, Č; Minić, S; Nikolić, M; Platanić Arizanović, L; Ristivojević, MK	1

Reviews

31 review(s) available for sertindole and olanzapine

Article	Year
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 18, Issue:2 Topics: Animals; Antipsychotic Agents; Humans	1998
Selective optimization of side activities: another way for drug discovery. Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6 Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship	2004
Clinical efficacy of serotonin-dopamine antagonists relative to classic neuroleptics. Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:1 Suppl 1 Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Dopamine Antagonists; Humans; Imidazoles; Indoles; Isoxazoles; Olanzapine; Piperidines; Pirenzepine; Risperidone; Schizophrenia; Serotonin Antagonists	1995
The new generation of antipsychotic drugs. International clinical psychopharmacology, 1996, Volume: 11 Suppl 2 Topics: Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Schizophrenia; Thiazoles	1996
Side effect profiles of new antipsychotic agents. The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 11 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neuroleptic Malignant Syndrome; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone; Schizophrenia; Seizures; Sleep; Weight Gain	1996
The promise of new drugs for schizophrenia treatment. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1997, Volume: 42, Issue:3 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	1997
[New antipsychotic drugs]. Harefuah, 1997, Volume: 133, Issue:1-2 Topics: Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Clinical Trials as Topic; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Pramipexole; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Thiazoles	1997
New antipsychotic medications: strategies for evaluation and selected findings. Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3 Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Administration Schedule; Drug Approval; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Placebos; Psychotic Disorders; Recurrence; Research Design; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; United States; United States Food and Drug Administration	1997
Treatment of the refractory schizophrenic patient. The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 1 Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Diagnosis, Differential; Humans; Imidazoles; Indoles; Olanzapine; Patient Compliance; Pirenzepine; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Terminology as Topic; Treatment Failure	1998
Olanzapine, sertindole and schizophrenia. Drug and therapeutics bulletin, 1997, Volume: 35, Issue:11 Topics: Antipsychotic Agents; Benzodiazepines; Drug Administration Schedule; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Schizophrenia	1997
New atypical antipsychotics. Experience and utility in the elderly. Drugs & aging, 1998, Volume: 12, Issue:2 Topics: Aged; Aging; Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Risperidone; Treatment Outcome	1998
Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics. Journal of affective disorders, 1998, Volume: 48, Issue:2-3 Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Risperidone; Trimipramine	1998
Efficacy and extrapyramidal side-effects of the new antipsychotics olanzapine, quetiapine, risperidone, and sertindole compared to conventional antipsychotics and placebo. A meta-analysis of randomized controlled trials. Schizophrenia research, 1999, Jan-04, Volume: 35, Issue:1 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Dibenzothiazepines; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	1999
Tardive dyskinesia in affective disorders. The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5 Topics: Adult; Affective Disorders, Psychotic; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Imidazoles; Indoles; Male; Olanzapine; Piperazines; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risk Assessment; Risk Factors; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome	1999
Drug metabolism and atypical antipsychotics. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:4 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cytochrome P-450 Enzyme System; Dibenzothiazepines; Drug Interactions; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia	1999
[New antipsychotic agents]. L'Encephale, 1999, Volume: 25 Spec No 3 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles	1999
Benefit-risk evaluation of olanzapine, risperidone and sertindole in the treatment of schizophrenia. European archives of psychiatry and clinical neuroscience, 1999, Volume: 249 Suppl 2 Topics: Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Risk Assessment; Risperidone; Schizophrenia	1999
[New i.e. atypical neuroleptic agents for negative symptoms of schizophrenia: results and methodological problems of evaluation]. Der Nervenarzt, 2000, Volume: 71, Issue:5 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Double-Blind Method; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neurotransmitter Agents; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulpiride; Thiazoles	2000
Atypical antipsychotics and weight gain--a systematic review. Acta psychiatrica Scandinavica, 2000, Volume: 101, Issue:6 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles; Weight Gain	2000
Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. BMJ (Clinical research ed.), 2000, Dec-02, Volume: 321, Issue:7273 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Costs; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Regression Analysis; Risperidone; Schizophrenia; Sulpiride	2000
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia. Annual review of medicine, 2001, Volume: 52 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Dopamine Antagonists; Drug Monitoring; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Sulpiride; Thiazoles; Treatment Outcome	2001
[Atypical neuroleptics: new approaches to drug therapy of schizophrenic disorders]. Wiener klinische Wochenschrift, 2000, Dec-22, Volume: 112, Issue:24 Topics: Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Dibenzothiepins; Haloperidol; Humans; Imidazoles; Indoles; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Placebos; Quetiapine Fumarate; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Thiazoles	2000
Cost effectiveness of the newer atypical antipsychotics: a review of the pharmacoeconomic research evidence. Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:1 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Dibenzothiazepines; Health Care Costs; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone	2001
[Schizoaffective disorder: clinical symptoms and present-day approach to treatment]. Medicina (Kaunas, Lithuania), 2002, Volume: 38, Issue:11 Topics: Adolescent; Amisulpride; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Child; Diagnosis, Differential; Dibenzothiazepines; Dogs; Female; Humans; Imidazoles; Indoles; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Olanzapine; Piperazines; Pirenzepine; Placebos; Prognosis; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Sulpiride; Thiazoles; Time Factors	2002
Antipsychotic medication and seizures: a review. Drugs of today (Barcelona, Spain : 1998), 2003, Volume: 39, Issue:7 Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles	2003
[Psychotropics and weight gain]. Praxis, 2004, Aug-25, Volume: 93, Issue:35 Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain	2004
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophrenia research, 2010, Volume: 123, Issue:2-3 Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Cholesterol; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Weight Gain	2010
Risperidone versus other atypical antipsychotics for schizophrenia. The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1 Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles	2011
[Pharmacoepidemiological and toxicological aspects of atypical neuroleptics usage]. Przeglad lekarski, 2011, Volume: 68, Issue:8 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Interactions; Humans; Imidazoles; Indoles; Olanzapine	2011
Maximizing response to first-line antipsychotics in schizophrenia: a review focused on finding from meta-analysis. Psychopharmacology, 2019, Volume: 236, Issue:2 Topics: Amisulpride; Antidepressive Agents; Antipsychotic Agents; Clozapine; Depression; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2019
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia. The American journal of psychiatry, 2020, 04-01, Volume: 177, Issue:4 Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes	2020

Trials

3 trial(s) available for sertindole and olanzapine

Article	Year
Novel antipsychotics: comparison of weight gain liabilities. The Journal of clinical psychiatry, 1999, Volume: 60, Issue:6 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Pirenzepine; Placebos; Retrospective Studies; Risperidone; Schizophrenia; Weight Gain	1999
Effects of newer atypical antipsychotics on autonomic neurocardiac function: a comparison between amisulpride, olanzapine, sertindole, and clozapine. Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:1 Topics: Adult; Amisulpride; Antipsychotic Agents; Autonomic Nervous System; Benzodiazepines; Clozapine; Electrocardiography; Female; Heart; Heart Rate; Humans; Imidazoles; Indoles; Male; Middle Aged; Olanzapine; Pirenzepine; Prospective Studies; Sulpiride	2001
The efficacy and safety of 12 weeks of treatment with sertindole or olanzapine in patients with chronic schizophrenia who did not respond successfully to their previous treatments: a randomized, double-blind, parallel-group, flexible-dose study. International clinical psychopharmacology, 2012, Volume: 27, Issue:6 Topics: Adolescent; Adult; Aged; Benzodiazepines; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imidazoles; Indoles; Male; Middle Aged; Olanzapine; Schizophrenia; Time Factors; Treatment Failure; Treatment Outcome; Young Adult	2012

Other Studies

36 other study(ies) available for sertindole and olanzapine

Article	Year
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Animals; Antipsychotic Agents; Brain; Cells, Cultured; Clozapine; Haloperidol; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone	1996
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists	2000
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. European journal of pharmacology, 2002, Aug-16, Volume: 450, Issue:1 Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG	2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation	2009
Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands. Bioorganic & medicinal chemistry letters, 2010, Sep-15, Volume: 20, Issue:18 Topics: Cell Line; HeLa Cells; Humans; Indoles; Ligands; Protein Binding; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Structure-Activity Relationship	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia. Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11 Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides	2014
The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine. Psychopharmacology, 1995, Volume: 119, Issue:4 Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Dibenzocycloheptenes; Dibenzoxepins; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Imidazoles; Indoles; Locomotion; Male; Olanzapine; Olfactory Pathways; Pirenzepine; Rats; Rats, Wistar; Risperidone; Thiazines; Time Factors	1995
Chronic olanzapine or sertindole treatment results in reduced oral chewing movements in rats compared to haloperidol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1998, Volume: 19, Issue:5 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dyskinesia, Drug-Induced; Haloperidol; Imidazoles; Indoles; Male; Mastication; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley	1998
Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Clozapine; Haloperidol; Imidazoles; Indoles; Injections, Intraperitoneal; Male; Neural Inhibition; Olanzapine; Pirenzepine; Prazosin; Rats; Rats, Wistar; Reflex, Startle; Remoxipride; Risperidone; Ritanserin; Serotonin Antagonists	1997
Effect of novel antipsychotic drugs on phencyclidine-induced stereotyped behaviour and social isolation in the rat social interaction test. Behavioural pharmacology, 1997, Volume: 8, Issue:2-3 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Dibenzothiazepines; Dose-Response Relationship, Drug; Hallucinogens; Imidazoles; Indoles; Interpersonal Relations; Male; Olanzapine; Phencyclidine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Wistar; Remoxipride; Social Isolation; Stereotypic Movement Disorder	1997
Quinpirole, 8-OH-DPAT and ketanserin modulate catalepsy induced by high doses of atypical antipsychotics. Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Benzodiazepines; Catalepsy; Clozapine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Indoles; Ketanserin; Male; Mice; Mice, Inbred BALB C; Olanzapine; Pirenzepine; Quinpirole; Random Allocation; Rats; Rats, Wistar; Risperidone; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity	1999
Clozapine discrimination with a low training dose distinguishes atypical from typical antipsychotic drugs in rats. Psychopharmacology, 2000, Volume: 149, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Discrimination Learning; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone	2000
Effects of atypical antipsychotic drugs on dopamine output in the shell and core of the nucleus accumbens: role of 5-HT(2A) and alpha(1)-adrenoceptor antagonism. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:4 Topics: Adrenergic Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Dopamine; Fluorobenzenes; Imidazoles; Indoles; Male; Nucleus Accumbens; Olanzapine; Piperidines; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Serotonin Antagonists	2000
Striatal and temporal cortical D2/D3 receptor occupancy by olanzapine and sertindole in vivo: a [123I]epidepride single photon emission tomography (SPET) study. Psychopharmacology, 2000, Volume: 150, Issue:2 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzamides; Benzodiazepines; Corpus Striatum; Female; Humans; Imidazoles; Indoles; Iodine Radioisotopes; Male; Middle Aged; Olanzapine; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Temporal Lobe; Tomography, Emission-Computed	2000
Traditional and new antipsychotic drugs differentially alter neurotransmission markers in basal ganglia-thalamocortical neural pathways. Synapse (New York, N.Y.), 2001, Volume: 39, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Corpus Striatum; Down-Regulation; Haloperidol; Imidazoles; Indoles; Male; Neurotransmitter Agents; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Thalamus; Up-Regulation	2001
Comparative study of mortality rates and cardiac dysrhythmias in post-marketing surveillance studies of sertindole and two other atypical antipsychotic drugs, risperidone and olanzapine. Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Cohort Studies; Death, Sudden; Electrocardiography; European Union; Female; Humans; Imidazoles; Indoles; Long QT Syndrome; Male; Middle Aged; Olanzapine; Pirenzepine; Product Surveillance, Postmarketing; Risperidone; Sex Factors	2001
Effects of acute versus chronic treatment with typical or atypical antipsychotics on d-amphetamine-induced sensorimotor gating deficits in rats. Psychopharmacology, 2001, Volume: 156, Issue:2-3 Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Central Nervous System Stimulants; Dextroamphetamine; Haloperidol; Hyperkinesis; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Time Factors	2001
Effects of antipsychotic drugs on operant responding after acute and repeated administration. Psychopharmacology, 2002, Volume: 160, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Operant; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Thioridazine; Time Factors	2002
Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis. Pharmaceutical research, 2006, Volume: 23, Issue:6 Topics: Action Potentials; Aged; Antipsychotic Agents; Benzodiazepines; Cell Line; Electrocardiography; Ether-A-Go-Go Potassium Channels; Humans; Imidazoles; In Vitro Techniques; Indoles; Ion Channels; Middle Aged; Molecular Structure; Myocytes, Cardiac; Neural Networks, Computer; Olanzapine; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Sodium Channels; Structure-Activity Relationship; Thioridazine; Transfection	2006
Sertindole, in contrast to clozapine and olanzapine, does not disrupt water maze performance after acute or chronic treatment. European journal of pharmacology, 2006, Aug-07, Volume: 542, Issue:1-3 Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Imidazoles; Indoles; Male; Maze Learning; Olanzapine; Psychomotor Performance; Rats; Rats, Wistar; Time Factors	2006
Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics. European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3 Topics: Administration, Oral; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Benzodiazepines; Binding, Competitive; Clozapine; Conditioning, Psychological; Dopamine Antagonists; Haloperidol; Imidazoles; Indoles; Injections, Subcutaneous; Male; Models, Biological; Olanzapine; Protein Binding; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Reproducibility of Results; Risperidone	2008
Associations between venous thromboembolism and antipsychotics. A study of the WHO database of adverse drug reactions. Drug safety, 2008, Volume: 31, Issue:8 Topics: Adult; Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Clopenthixol; Databases, Factual; Female; Humans; Imidazoles; Indoles; Male; Middle Aged; Olanzapine; Time Factors; Venous Thromboembolism; World Health Organization; Young Adult	2008
Effects of olanzapine, sertindole and clozapine on learning and memory in the Morris water maze test in naive and MK-801-treated mice. Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:3 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Imidazoles; Indoles; Learning; Male; Maze Learning; Memory; Mice; Mice, Inbred BALB C; Olanzapine	2011
Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics. Early intervention in psychiatry, 2009, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Clopenthixol; Clozapine; Female; Humans; Imidazoles; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Olanzapine; Perphenazine; Psychotic Disorders; Risperidone; Statistics, Nonparametric; Time Factors; Young Adult	2009
Effects of olanzapine, sertindole and clozapine on MK-801 induced visual memory deficits in mice. Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Imidazoles; Indoles; Learning; Male; Memory Disorders; Mice; Mice, Inbred BALB C; Motor Activity; Olanzapine; Recognition, Psychology; Visual Perception	2011
A pharmacoeconomic analysis of sertindole in the treatment of schizophrenia in Sweden. Nordic journal of psychiatry, 2011, Volume: 65, Issue:6 Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cost-Benefit Analysis; Economics, Pharmaceutical; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Models, Economic; National Health Programs; Olanzapine; Piperazines; Quinolones; Risperidone; Schizophrenia; Sweden	2011
Effect of atypical antipsychotics on antioxidant enzyme activities in human erythrocytes (in vitro study). Human psychopharmacology, 2013, Volume: 28, Issue:1 Topics: Adult; Amisulpride; Antioxidants; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Catalase; Clozapine; Dibenzothiazepines; Enzyme Activation; Erythrocytes; Glutathione Peroxidase; Glutathione Reductase; Humans; Imidazoles; Indoles; Male; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Sulpiride; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles; Treatment Outcome; Young Adult	2013
Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes? International journal of molecular sciences, 2023, May-17, Volume: 24, Issue:10 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Molecular Docking Simulation; Olanzapine	2023