Compounds > sch 37370
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sch 37370 and piperidines

sch 37370 has been researched along with piperidines in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Affrime, MB; Billah, MM; Brannan, MD; Christopher, JD; Eckel, SP; Gilchrest, HG; Granzow, CA; Lawton, PJ; Radwanski, E; Richards, W1
Billah, MM; Chapman, RW; Egan, RW; Kreutner, W; Siegel, MI; Watnick, AS1
Billah, MM; Egan, RW; Ganguly, AK; Green, MJ; Kreutner, W; Piwinski, JJ; Siegel, MI; Villani, FJ; Wong, JK1
Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE1
Centemeri, C; Ciceri, P; Colli, S; Nicosia, S; Tosarello, D1
Billah, MM; Carruthers, NI; Chan, TM; Kaminski, JJ; McPhail, AT; Tozzi, S; Wong, SC1

Trials

1 trial(s) available for sch 37370 and piperidines

ArticleYear
Differential plasma duration of antiplatelet-activating factor and antihistamine activities of oral Sch 37370 in humans.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:2

    Topics: Administration, Oral; Adult; Double-Blind Method; Electrocardiography; Histamine Antagonists; Humans; Loratadine; Male; Piperidines; Platelet Activating Factor

1992

Other Studies

5 other study(ies) available for sch 37370 and piperidines

ArticleYear
Sch 37370: a new drug combining antagonism of platelet-activating factor (PAF) with antagonism of histamine.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Animals; Antigens; Bronchial Spasm; Guinea Pigs; Histamine Antagonists; Humans; Hyperventilation; Loratadine; Male; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Lew

1991
Discovery and preliminary pharmacology of Sch 37370, a dual antagonist of PAF and histamine.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Histamine Antagonists; Humans; Kinetics; Loratadine; Male; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship

1991
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats

1990
Heterogeneous platelet-activating factor (PAF) receptors and calcium increase in platelets and macrophages.
    Biochemical pharmacology, 1999, Feb-01, Volume: 57, Issue:3

    Topics: Animals; Azepines; Blood Platelets; Calcium; Cytosol; Humans; Loratadine; Macrophages; Male; Piperidines; Platelet Membrane Glycoproteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles

1999
Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:7

    Topics: Animals; Anti-Allergic Agents; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Histamine Antagonists; Humans; Inhibitory Concentration 50; Isoquinolines; Loratadine; Mice; Models, Molecular; Molecular Conformation; Molecular Mimicry; Piperazines; Piperidines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rats; Receptors, Histamine H1; Stereoisomerism; Structure-Activity Relationship

1999