sb 216763 and rotenone
sb 216763 has been researched along with rotenone in 4 studies
Compound Research Comparison
| Studies (sb 216763) | Trials (sb 216763) | Recent Studies (post-2010) (sb 216763) | Studies (rotenone) | Trials (rotenone) | Recent Studies (post-2010) (rotenone) |
|---|---|---|---|---|---|
| 342 | 0 | 225 | 4,407 | 6 | 1,648 |
Protein Interaction Comparison
| Protein | Taxonomy | sb 216763 (IC50) | rotenone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8 | |
| NADH-ubiquinone oxidoreductase chain 1 | Bos taurus (cattle) | 0.015 | |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Bos taurus (cattle) | 0.0051 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3.6486 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.87 | |
| Acyl carrier protein, mitochondrial | Bos taurus (cattle) | 0.0051 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Akaike, A; Hongo, H; Izumi, Y; Kihara, T; Kume, T; Niidome, T; Sugimoto, H | 1 |
| Cen, L; Feng, J; Li, S; Luo, Q; Mo, M; Qu, S; Sun, C; Wei, L; Xiao, Y; Xu, P; Yang, X; Zhang, L | 1 |
Other Studies
4 other study(ies) available for sb 216763 and rotenone
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization.
Topics: Cell Line, Tumor; Electron Transport Complex I; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Maleimides; Microtubules; Paclitaxel; Parkinson Disease, Secondary; Phosphorylation; Reactive Oxygen Species; Rotenone; tau Proteins; Tubulin Modulators | 2012 |
Enhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction.
Topics: Animals; Apoptosis; beta Catenin; Caspase 3; Cell Survival; Dopaminergic Neurons; Gene Expression Regulation; Gene Silencing; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lithium Chloride; Maleimides; Nuclear Receptor Subfamily 4, Group A, Member 2; PC12 Cells; Protein Binding; Rats; RNA Interference; RNA, Small Interfering; Rotenone; Uncoupling Agents; Wnt Signaling Pathway | 2016 |