Page last updated: 2024-09-05

sb 216763 and azd2858

sb 216763 has been researched along with azd2858 in 2 studies

Compound Research Comparison

Studies
(sb 216763)
Trials
(sb 216763)
Recent Studies (post-2010)
(sb 216763)
Studies
(azd2858)
Trials
(azd2858)
Recent Studies (post-2010) (azd2858)
3420225808

Protein Interaction Comparison

ProteinTaxonomysb 216763 (IC50)azd2858 (IC50)
Glycogen synthase kinase-3 betaHomo sapiens (human)0.005
Glycogen synthase kinase-3 betaMus musculus (house mouse)0.076

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Berg, S; Bergh, M; Bhat, R; Hellberg, S; Högdin, K; Jerning, E; Lo-Alfredsson, Y; Neelissen, J; Nilsson, Y; Ormö, M; Söderman, P; Tucker, J; von Berg, S; Weigelt, T; Xue, Y1
Feng, F; Jiang, X; Liu, X; Sun, H; Wang, Y; Xu, J; Xu, K; Zhou, J1

Other Studies

2 other study(ies) available for sb 216763 and azd2858

ArticleYear
Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
    Journal of medicinal chemistry, 2012, Nov-08, Volume: 55, Issue:21

    Topics: 3T3 Cells; Alzheimer Disease; Animals; Blood-Brain Barrier; Caco-2 Cells; Cattle; Crystallography, X-Ray; Drug Design; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Models, Molecular; Molecular Structure; Permeability; Phosphorylation; Pyrazines; Solubility; Sulfonamides; tau Proteins

2012
PROTACs suppression of GSK-3β, a crucial kinase in neurodegenerative diseases.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Enzyme Inhibitors; Glycogen Synthase Kinase 3 beta; HT29 Cells; Humans; Models, Molecular; Neurodegenerative Diseases; PC12 Cells; Proteolysis; Rats; Small Molecule Libraries

2021
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