rwj-37947 and irosustat

rwj-37947 has been researched along with irosustat* in 1 studies

Other Studies

1 other study(ies) available for rwj-37947 and irosustat

Article	Year
Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II. Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5 We describe the docking of selected steroidal and non-steroidal estrone sulphatase inhibitors, including the Phase I clinical trial candidate 667COUMATE (6), into the active site of human carbonic anhydrase II (hCA II). The docking scores are compared with the inhibition of hCA II and show good correlation with biological activity. Topics: Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Coumarins; Estrone; Humans; Inhibitory Concentration 50; Models, Molecular; Steroids; Structure-Activity Relationship; Substrate Specificity; Sulfatases; Sulfonamides; Sulfonic Acids	2003

Article

Year

Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II.

Bioorganic & medicinal chemistry letters, 2003, Mar-10, Volume: 13, Issue:5

We describe the docking of selected steroidal and non-steroidal estrone sulphatase inhibitors, including the Phase I clinical trial candidate 667COUMATE (6), into the active site of human carbonic anhydrase II (hCA II). The docking scores are compared with the inhibition of hCA II and show good correlation with biological activity.

Topics: Binding Sites; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Coumarins; Estrone; Humans; Inhibitory Concentration 50; Models, Molecular; Steroids; Structure-Activity Relationship; Substrate Specificity; Sulfatases; Sulfonamides; Sulfonic Acids

2003