rs 127445 has been researched along with mdl 100907 in 10 studies
| Studies (rs 127445) | Trials (rs 127445) | Recent Studies (post-2010) (rs 127445) | Studies (mdl 100907) | Trials (mdl 100907) | Recent Studies (post-2010) (mdl 100907) |
|---|---|---|---|---|---|
| 29 | 1 | 18 | 1,241 | 65 | 539 |
| Protein | Taxonomy | rs 127445 (IC50) | mdl 100907 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0048 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Chen, Z; Collier, T; Fu, H; Liang, SH; Rong, J; Zhou, J | 1 |
| Bassil, AK; Bolton, VJ; Brown, JD; Bruton, G; Cutler, L; Gray, KM; Lee, K; Sanger, GJ; Summerfield, SG; Taylor, CM; Winchester, WJ | 1 |
| Furness, JB; Gale, JD; Himaki, D; Kawai, M; Kurebayashi, Y; Nagao, K; Ohashi-Doi, K | 1 |
| Bongiovanni, C; Bulmer, DC; Coelho, AM; Cryan, JF; Dinan, TG; Fitzgerald, P; Lee, K; O'Mahony, SM; Winchester, W | 1 |
| Diaz, SL; Maroteaux, L | 1 |
| Barragán-Iglesias, P; Bravo-Hernández, M; Cervantes-Durán, C; Granados-Soto, V; Murbartián, J; Pineda-Farias, JB; Vidal-Cantú, GC | 1 |
| Caraci, F; Cathala, A; Devroye, C; Di Marco, B; Drago, F; Piazza, PV; Spampinato, U | 1 |
| Cathala, A; Devroye, C; Drago, F; Haddjeri, N; Piazza, PV; Rovera, R; Spampinato, U; Vallée, M | 1 |
| Chen, L; Dong, J; Li, Y; Shen, Y; Wan, C; Wang, H; Wen, F; Wu, Y; Yang, T; Zeng, Z | 1 |
1 review(s) available for rs 127445 and mdl 100907
| Article | Year |
|---|---|
Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors.
Topics: Brain; Humans; Ligands; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Serotonin | 2022 |
9 other study(ies) available for rs 127445 and mdl 100907
| Article | Year |
|---|---|
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology.
Topics: Animals; Cell Line; Colon; Defecation; Gastrointestinal Motility; Humans; In Vitro Techniques; Intestine, Large; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists | 2009 |
A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats.
Topics: Analysis of Variance; Animals; Colon; Dose-Response Relationship, Drug; Hypersensitivity; Indoles; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Pain Measurement; Pain Threshold; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Restraint, Physical; Serotonin 5-HT2 Receptor Antagonists; Statistics, Nonparametric; Stress, Physiological; Trinitrobenzenesulfonic Acid; Urea | 2010 |
5-HT(2B) receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Hyperalgesia; Intestine, Large; Irritable Bowel Syndrome; Pain; Pain Measurement; Pain Threshold; Pyrimidines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2010 |
Implication of 5-HT(2B) receptors in the serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Mice; Mice, 129 Strain; Mice, Transgenic; Motor Activity; Pyrimidines; Random Allocation; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Serotonin Syndrome | 2011 |
Role of peripheral and spinal 5-HT2B receptors in formalin-induced nociception.
Topics: Amphetamines; Animals; Behavior, Animal; Female; Injections, Spinal; Pain; Pain Measurement; Peripheral Nerves; Pyrimidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists; Spinal Cord | 2012 |
Central serotonin(2B) receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Motor Activity; Pyrimidines; Quinpirole; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Differential control of dopamine ascending pathways by serotonin2B receptor antagonists: New opportunities for the treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Prefrontal Cortex; Pyrimidines; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists | 2016 |
Serotonin receptors 5-HTR2A and 5-HTR2B are involved in cigarette smoke-induced airway inflammation, mucus hypersecretion and airway remodeling in mice.
Topics: Airway Remodeling; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Injections, Intraperitoneal; Ketanserin; Lung; Male; Mice; Mucus; Nicotiana; Pulmonary Disease, Chronic Obstructive; Pyrimidines; Quercetin; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Respiratory Mucosa; Serotonin 5-HT2 Receptor Antagonists; Smoke; Specific Pathogen-Free Organisms | 2020 |