roxifiban has been researched along with tirofiban in 6 studies
| Studies (roxifiban) | Trials (roxifiban) | Recent Studies (post-2010) (roxifiban) | Studies (tirofiban) | Trials (tirofiban) | Recent Studies (post-2010) (tirofiban) |
|---|---|---|---|---|---|
| 40 | 7 | 1 | 1,210 | 309 | 427 |
| Protein | Taxonomy | roxifiban (IC50) | tirofiban (IC50) |
|---|---|---|---|
| Integrin subunit alpha 2b | Rattus norvegicus (Norway rat) | 0.13 | |
| Integrin beta-3 | Homo sapiens (human) | 0.1184 | |
| Integrin alpha-V | Homo sapiens (human) | 0.011 | |
| Integrin alpha-IIb | Homo sapiens (human) | 0.1225 | |
| Integrin beta-3 | Rattus norvegicus (Norway rat) | 0.13 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gretler, DD; Scarborough, RM | 1 |
| Bozarth, JM; Forsythe, MS; Mousa, SA; Slee, A | 1 |
| Caron, A; Merhi, Y; Mousa, SA; Théorêt, JF | 1 |
| Barbera, FA; Dorsam, RT; Feuerstein, GZ; Friedman, SM; Gibbs, S; Lauver, A; Savion, N; Varon, D; Wang, H; Wang, X | 1 |
| Connor, JH; Connor, RF; Hantgan, RR; Mousa, SA; Stahle, MC | 1 |
| Hantgan, RR; Stahle, MC | 1 |
1 review(s) available for roxifiban and tirofiban
| Article | Year |
|---|---|
Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.
Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Drug Design; Fibrinolytic Agents; Humans; Injections; Integrins; Molecular Mimicry; Peptides; Platelet Glycoprotein GPIIb-IIIa Complex; Snake Venoms | 2000 |
5 other study(ies) available for roxifiban and tirofiban
| Article | Year |
|---|---|
Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels.
Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Calcium; Citric Acid; Eptifibatide; Fibrinogen; Heparin; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Isoxazoles; Peptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Tirofiban; Tyrosine | 2000 |
Anti-platelet effects of GPIIb/IIIa and P-selectin antagonism, platelet activation, and binding to neutrophils.
Topics: Abciximab; Amidines; Analysis of Variance; Antibodies, Monoclonal; Cells, Cultured; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Neutrophils; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Tirofiban; Tyrosine | 2002 |
Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.
Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cell Aggregation; Dose-Response Relationship, Drug; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Peptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Rheology; Shear Strength; Temperature; Tirofiban; Tyrosine | 2002 |
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists.
Topics: Administration, Oral; Alanine; Amidines; Binding, Competitive; Blood Platelets; Dimerization; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Humans; In Vitro Techniques; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Isoxazoles; Kinetics; Male; Models, Molecular; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrrolidines; Reference Values; Structure-Activity Relationship; Tirofiban; Tyrosine | 2007 |
Integrin priming dynamics: mechanisms of integrin antagonist-promoted alphaIIbbeta3:PAC-1 molecular recognition.
Topics: Amidines; Dual Specificity Phosphatase 2; Eptifibatide; Integrins; Intercellular Signaling Peptides and Proteins; Isoxazoles; Models, Molecular; Peptides; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Thermodynamics; Tirofiban; Tyrosine | 2009 |