roxifiban and fibrinogen
roxifiban has been researched along with fibrinogen in 4 studies
Compound Research Comparison
| Studies (roxifiban) | Trials (roxifiban) | Recent Studies (post-2010) (roxifiban) | Studies (fibrinogen) | Trials (fibrinogen) | Recent Studies (post-2010) (fibrinogen) |
|---|---|---|---|---|---|
| 40 | 7 | 1 | 34,477 | 1,707 | 7,083 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bozarth, JM; Forsythe, MS; Mousa, SA; Slee, A | 1 |
| Bozarth, JM; Mousa, SA; Naik, UP; Slee, A | 1 |
| Bradley, JD; Cain, VA; Feuerstein, GZ; Hua, TA; Kornhauser, DM; Martin, DE; Munzer, DA; Seiffert, D; Stern, AM; Tchinnes, MA; Thomas, BE | 1 |
| Connor, JH; Connor, RF; Hantgan, RR; Mousa, SA; Stahle, MC | 1 |
Trials
1 trial(s) available for roxifiban and fibrinogen
| Article | Year |
|---|---|
Effects of the glycoprotein IIb/IIIa antagonist Roxifiban on P-selectin expression, fibrinogen binding, and microaggregate formation in a phase I dose-finding study: no evidence for platelet activation during treatment with a glycoprotein IIb/IIIa antagon
Topics: Adenosine Diphosphate; Adult; Amidines; Biomarkers; Dose-Response Relationship, Drug; Female; Fibrinogen; Humans; Isoxazoles; Male; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Receptors, Thrombin | 2003 |
Other Studies
3 other study(ies) available for roxifiban and fibrinogen
| Article | Year |
|---|---|
Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels.
Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Blood Platelets; Calcium; Citric Acid; Eptifibatide; Fibrinogen; Heparin; Humans; Immunoglobulin Fab Fragments; Iodine Radioisotopes; Isoxazoles; Peptides; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Pyrrolidines; Tirofiban; Tyrosine | 2000 |
Platelet GPIIb/IIIa binding characteristics of small molecule RGD mimetic: distinct binding profile for Roxifiban.
Topics: Amidines; Binding, Competitive; Blood Platelets; Collagen; Fibrinogen; Fibrinolytic Agents; Humans; Inhibitory Concentration 50; Isoxazoles; Kinetics; Ligands; Microscopy, Confocal; Molecular Mimicry; Oligopeptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Structure-Activity Relationship; Thermodynamics | 2001 |
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists.
Topics: Administration, Oral; Alanine; Amidines; Binding, Competitive; Blood Platelets; Dimerization; Dose-Response Relationship, Drug; Eptifibatide; Female; Fibrinogen; Humans; In Vitro Techniques; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Isoxazoles; Kinetics; Male; Models, Molecular; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Protein Conformation; Pyrrolidines; Reference Values; Structure-Activity Relationship; Tirofiban; Tyrosine | 2007 |