Page last updated: 2024-09-03

rg 12525 and wy 48252

rg 12525 has been researched along with wy 48252 in 4 studies

Compound Research Comparison

Studies
(rg 12525)
Trials
(rg 12525)
Recent Studies (post-2010)
(rg 12525)
Studies
(wy 48252)
Trials
(wy 48252)
Recent Studies (post-2010) (wy 48252)
14301500

Protein Interaction Comparison

ProteinTaxonomyrg 12525 (IC50)wy 48252 (IC50)
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)3.3
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)6.2
Platelet-activating factor acetylhydrolaseHomo sapiens (human)2
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)6.2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreft, AF; Musser, JH1
Krell, RD; Shaw, A1
Campbell, HF; Carnathan, GW; Galemmo, RA; Huang, FC; Johnson, WH; Mencel, JJ; Morrissette, MM; Nuss, GW; Poli, GB; Warus, JD1
Brooks, CD; Summers, JB1

Reviews

3 review(s) available for rg 12525 and wy 48252

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines

1992
Peptide leukotrienes: current status of research.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Acetophenones; Humans; Leukotriene Antagonists; Leukotrienes; Molecular Structure; Peptides; Receptors, Immunologic; Receptors, Leukotriene; Tetrazoles

1991
Modulators of leukotriene biosynthesis and receptor activation.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene

1996

Other Studies

1 other study(ies) available for rg 12525 and wy 48252

ArticleYear
Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: Animals; Azoles; Bronchodilator Agents; Chemical Phenomena; Chemistry; Guinea Pigs; Leukotriene Antagonists; Lung; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene B4; SRS-A; Structure-Activity Relationship; Tetrazoles

1990