quinone has been researched along with etoposide in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| de Vries, J; Lafleur, MV; Lankelma, J; Mans, DR; Retèl, J; Van Maanen, JM; Van Schaik, MA; Vermeulen, NP | 1 |
| Day, BW; Fan, Y; Giorgianni, A; Schreiber, EM; Yalowich, JC | 1 |
| Bender, RP; Osheroff, N | 1 |
| Alegria, AE; Garcia, C; Gonzalez, FA; Gordaliza, M; Kumar, A; Orellano, A; Sanchez-Cruz, P; Zayas, B | 1 |
| Deweese, JE; Jacob, DA; Mercer, SL; Osheroff, N | 1 |
| Ashley, RE; Deweese, JE; Lindsey, RH; Mercer, SL; Osheroff, N; Pendleton, M | 1 |
7 other study(ies) available for quinone and etoposide
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effects of oxygen radical scavengers on the inactivation of SS phi X174 DNA by the semi-quinone free radical of the antitumor agent etoposide.
Topics: Bacteriophage phi X 174; Benzoquinones; Butanols; Catalase; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Dimethyl Sulfoxide; DNA, Single-Stranded; DNA, Viral; Edetic Acid; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Hydrogen-Ion Concentration; Quinones; Superoxide Dismutase; Superoxides; tert-Butyl Alcohol | 1990 |
Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells.
Topics: Benzoquinones; Catalysis; Chromatography, Liquid; DNA Adducts; Etoposide; Glutathione; HL-60 Cells; Humans; Mass Spectrometry; Peroxidase | 2006 |
Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate.
Topics: Alanine; Amino Acid Substitution; Antigens, Neoplasm; Benzoquinones; Cysteine; DNA Cleavage; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Superhelical; Etoposide; Humans; Kinetics; Mass Spectrometry; Models, Molecular; Mutant Proteins; Mutation; Protein Structure, Tertiary; Quinones; Recombinant Proteins; Temperature | 2007 |
Thiols oxidation and covalent binding of BSA by cyclolignanic quinones are enhanced by the magnesium cation.
Topics: Antineoplastic Agents; Benzoquinones; Cations, Divalent; Chelating Agents; DNA Topoisomerases, Type II; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Etoposide; Glutathione; Magnesium Chloride; Models, Molecular; Molecular Structure; Oxidation-Reduction; Podophyllotoxin; Protein Binding; Quinones; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Topoisomerase II Inhibitors | 2008 |
Etoposide quinone is a redox-dependent topoisomerase II poison.
Topics: Antigens, Neoplasm; Benzoquinones; Catechols; Dithiothreitol; DNA Adducts; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Stability; Etoposide; Humans; Leukemia, Myeloid, Acute; Oxidation-Reduction; Reducing Agents | 2011 |
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism.
Topics: Antigens, Neoplasm; Benzoquinones; Binding Sites; Biocatalysis; Catalytic Domain; DNA Cleavage; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Circular; DNA, Superhelical; Etoposide; Humans; Kinetics; Models, Molecular; Molecular Conformation; Peptide Fragments; Protein Interaction Domains and Motifs; Recombinant Fusion Proteins; Stereoisomerism; Substrate Specificity; Topoisomerase II Inhibitors | 2014 |