Page last updated: 2024-08-18

pyrroles and y 27632

pyrroles has been researched along with y 27632 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (66.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishizaki, T; Keel, J; Maekawa, M; Narumiya, S; Nonomura, K; Tamechika, I; Uehata, M1
Lan, C; Vollrath, B; Wickman, G1
Abe, K; Misawa, M1
Fyhrquist, F; Nyman, T; Saijonmaa, O; Stewen, P1
Hatta, T; Irie, H; Kameyama, H; Kusaba, T; Kuwahara, N; Matsubara, H; Narumiya, H; Sasaki, S; Takeda, K; Tamagaki, K1
Goez, P; Hagelgans, A; Hempel, U; Heyne, B; Jaross, W; Menschikowski, M; Neumeister, V; Siegert, G1
Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M1
Ichihara, K; Itagaki, M; Satoh, K; Takaguri, A; Tokumitsu, Y1
Motley, ED; Watts, VL1
Akaike, A; Ito, R; Izumi, Y; Katsuki, H; Kume, T; Niidome, T; Sugimoto, H; Taguchi, R; Takada-Takatori, Y1
Amobi, NI; Guillebaud, J; Smith, IC1
Du, J; Gao, G; Jin, Y; Li, H; Li, Y; Liu, H; Liu, T; Pei, G; Wei, B; Wei, L; Yue, R1
Gui, Y; Jiang, J; Li, D; Li, H; Li, J; Tian, R; Walsh, MP; Wang, L; Wang, Y; Wang, Z; Yin, H; Zheng, XL1
Hou, T; Lee, SM; Li, C; Li, D; Li, Y; Pan, P; Shen, M; Sun, H; Tian, S; Zhou, H1
Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A1

Other Studies

15 other study(ies) available for pyrroles and y 27632

ArticleYear
Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: 3T3 Cells; Amides; Animals; Biological Transport; Cell Division; Cell Size; Enzyme Inhibitors; HeLa Cells; Humans; Interphase; Intracellular Signaling Peptides and Proteins; Mice; Mitosis; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; rho-Associated Kinases; S Phase

2000
Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm.
    Circulation research, 2003, Apr-18, Volume: 92, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Basilar Artery; Benzamides; Biological Transport; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Muscle, Smooth, Vascular; Oxyhemoglobins; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rabbits; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstriction

2003
Astrocyte stellation induced by Rho kinase inhibitors in culture.
    Brain research. Developmental brain research, 2003, Jun-12, Volume: 143, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Astrocytes; Carbazoles; Cell Size; Cells, Cultured; Cerebral Cortex; Colchicine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gout Suppressants; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Phalloidine; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; rho-Associated Kinases

2003
Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:6

    Topics: Amides; Atorvastatin; Cell Division; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Mevalonic Acid; Peptidyl-Dipeptidase A; Phosphorylation; Polyisoprenyl Phosphates; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; rho-Associated Kinases; RNA, Messenger; Sesquiterpenes; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A

2004
HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
    Cardiovascular research, 2004, Nov-01, Volume: 64, Issue:2

    Topics: Amides; Analysis of Variance; Angiotensin II; Atorvastatin; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucuronidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules; Klotho Proteins; Membrane Proteins; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; RNA, Messenger

2004
Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Amides; Aorta; Atorvastatin; Bacterial Proteins; Bacterial Toxins; Butadienes; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Drug Synergism; Flavonoids; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Janus Kinase 2; Lovastatin; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Pyrroles; RNA Stability; Up-Regulation

2005
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea

2007
Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:1

    Topics: 3T3-L1 Cells; Adaptor Proteins, Signal Transducing; Adipocytes; ADP Ribose Transferases; Amides; Animals; Atorvastatin; Botulinum Toxins; Dose-Response Relationship, Drug; Glucose; Glucose Transporter Type 4; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Mice; Phosphorylation; Polyisoprenyl Phosphates; Pravastatin; Protein Kinase Inhibitors; Protein Prenylation; Protein Transport; Proto-Oncogene Proteins c-akt; Pyridines; Pyrroles; rab4 GTP-Binding Proteins; Receptor, Insulin; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction

2008
Role of protease-activated receptor-1 in endothelial nitric oxide synthase-Thr495 phosphorylation.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:2

    Topics: ADP Ribose Transferases; Amides; Botulinum Toxins; Cells, Cultured; Endothelial Cells; Genes, Dominant; Humans; Models, Biological; Nitric Oxide Synthase Type III; Nitrites; Oligopeptides; Phosphorylation; Phosphothreonine; Pyridines; Pyrroles; Quinazolines; Receptor, PAR-1; Receptor, PAR-2; rho-Associated Kinases; rhoA GTP-Binding Protein; Thrombin; Umbilical Veins

2009
Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:1

    Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors

2009
Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility.
    Experimental physiology, 2012, Volume: 97, Issue:5

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Amides; Apamin; Calcium Channel Agonists; Calcium Channels, L-Type; Humans; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Contraction; Norepinephrine; Peptides; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Purinergic P2X Receptor Agonists; Pyridines; Pyrophosphatases; Pyrroles; Receptors, Purinergic P2X; rho-Associated Kinases; Suramin; Vas Deferens

2012
Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition.
    Developmental cell, 2012, May-15, Volume: 22, Issue:5

    Topics: Amides; Animals; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Endothelial Cells; Flow Cytometry; Hematopoiesis; Hematopoietic Stem Cells; Mice; Pyridines; Pyrroles; Quinazolines; Receptors, Thrombin; rho-Associated Kinases; rhoA GTP-Binding Protein; Zebrafish

2012
Atorvastatin inhibits myocardin expression in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:1

    Topics: Actins; Amides; Animals; Aorta; Atorvastatin; Blotting, Western; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Polyisoprenyl Phosphates; Potassium Chloride; Pyridines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Trans-Activators; Vasoconstriction

2012
Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays.
    Scientific reports, 2015, Nov-16, Volume: 5

    Topics: Actin Depolymerizing Factors; Amides; Animals; Atorvastatin; Binding Sites; Cerebral Hemorrhage; Databases, Chemical; Databases, Protein; Disease Models, Animal; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridines; Pyrroles; rho-Associated Kinases; Signal Transduction; Structure-Activity Relationship; Zebrafish

2015
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
    Nature communications, 2016, Feb-08, Volume: 7

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles

2016