Compounds > pyrroles
Page last updated: 2024-08-18

pyrroles and u 74006f

pyrroles has been researched along with u 74006f in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hinds, TR; Rohn, TT; Vincenzi, FF1
Althaus, JS; Fici, GJ; VonVoigtlander, PF1
Mizsak, SA; Pearson, PG; Sanders, PE; Streeper, RT; Vrbanac, JJ; Wienkers, LC; Zhao, Z1
Hall, ED; Smith, SL1
Burmester, GR; Buttgereit, F; Fici, G; Schmid, D; Tripmacher, R; von Voigtlander, P1

Other Studies

5 other study(ies) available for pyrroles and u 74006f

ArticleYear
Inhibition of Ca2+-pump ATPase and the Na+/K+-pump ATPase by iron-generated free radicals. Protection by 6,7-dimethyl-2,4-DI-1- pyrrolidinyl-7H-pyrrolo[2,3-d] pyrimidine sulfate (U-89843D), a potent, novel, antioxidant/free radical scavenger.
    Biochemical pharmacology, 1996, Feb-23, Volume: 51, Issue:4

    Topics: Antioxidants; Blotting, Western; Calcium-Transporting ATPases; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Ferrous Compounds; Free Radical Scavengers; Free Radicals; Humans; Kinetics; Membrane Proteins; Pregnatrienes; Pyrimidines; Pyrroles; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances

1996
Effects of lazaroids and a peroxynitrite scavenger in a cell model of peroxynitrite toxicity.
    Free radical biology & medicine, 1997, Volume: 22, Issue:1-2

    Topics: Animals; Antioxidants; Cells, Cultured; Cerebellum; Free Radical Scavengers; Models, Biological; Neuroprotective Agents; Nitrates; Pregnatrienes; Pyrimidines; Pyrroles; Pyrrolidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley

1997
In vitro metabolic transformations of 2,4-dipyrrolidinylpyrimidine: a chemical probe for P450-mediated oxidation of tirilazad mesylate.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:11

    Topics: Animals; Antioxidants; Biotransformation; Chromatography, Liquid; Cyanides; Cytochrome P-450 Enzyme System; Deuterium; Free Radical Scavengers; Hydroxylation; Male; Mass Spectrometry; Oxidation-Reduction; Pregnatrienes; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley

1997
Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome.
    Journal of neurotrauma, 1998, Volume: 15, Issue:9

    Topics: Age Factors; Animals; Battered Child Syndrome; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Glutamic Acid; Head Injuries, Closed; Humans; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Pregnatrienes; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors

1998
Short-term effects of the 21-aminosteroid lazaroid tirilazad mesylate (PNU-74006F) and the pyrrolopyrimidine lazaroid PNU-101033E on energy metabolism of human peripheral blood mononuclear cells.
    Bioscience reports, 2001, Volume: 21, Issue:1

    Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Brain Injuries; Calcium-Transporting ATPases; Cell Membrane; Cell Respiration; Concanavalin A; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Protein Biosynthesis; Proteins; Pyrimidines; Pyrroles; Sodium-Potassium-Exchanging ATPase; Time Factors

2001