pyrroles has been researched along with tws 119 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (86.36) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, T; Cui, J; Dong, H; Liu, L; Zeng, FY | 1 |
| Ikeda, Y; Matsubara, Y; Murata, M; Ono, M; Shibano, T | 1 |
| Bollard, C; Chakraborty, R; Dotti, G; Hanley, PJ; Liu, E; Muralidharan, S; Rodgers, J; Rooney, C; Savoldo, B; Shpall, E | 1 |
| Arbour, N; Forget, MA; Grange, C; Huon, Y; Lapointe, R; Liberman, M; Martin, J; Mes-Masson, AM; Reuben, A | 1 |
| Li, L; Smyth, K; Sun, Z; Xiao, Z | 1 |
| Ito, K; Koide, N; Komatsu, T; Naiki, Y; Odkhuu, E; Tsolmongyn, B; Yokochi, T; Yoshida, T | 1 |
| Chen, F; Chen, Y; Liu, J; Lv, X; Sun, L; Zhang, J; Zhang, S; Zheng, L; Zhou, Z | 1 |
| Gui, Y; Li, L; Shi, Z; Singh, P; Walsh, MP; Yin, H; Yu, YN; Zheng, XL; Zhou, YX | 1 |
| Chen, Q; Deng, G; Li, M; Li, Q; Wan, J; Wang, J; Wang, W; Wang, Y; Yang, Q | 1 |
| Delorenzi, M; Dormond, O; Fajas, L; Grandclément, C; Held, W; Jandus, C; Lopez-Mejia, IC; Romero, P; Scholz, G; Soneson, C; Zhang, L | 1 |
| Cho, H; Choi, KS; Jeong, DS; Jeong, MH; Kang, JS; Kim, HJ; Lee, DI; O'Rourke, B; Pyun, JH; Solhjoo, S; Tomaselli, GF | 1 |
| Chen, Q; Guan, F; Li, M; Wang, J; Wang, W; Wang, Y; Wang, Z; Zhang, W | 1 |
| Aldarouish, M; Chen, FX; Chen, YQ; Liu, JQ; Pan, N; Wang, LX; Zheng, L; Zhou, ZH | 1 |
| Gu, Y; Hong, H; Lei, YY; Lu, CG; Sheng, SY; Tang, YY; Zhang, YQ; Zou, JY | 1 |
| Chen, X; Deng, H; Huang, H; Ji, S; Jin, W; Shen, J; Shen, Q; Tang, H; Yan, P; Zhang, J; Zhao, X | 1 |
| Chang, JT; Davies, P; Den Hollander, P; Gao, R; Joseph, R; Mani, SA; Miura, N; Pietila, M; Ramirez-Pena, E; Rosen, JM; Sarkar, TR; Shariati, M; Sobieski, M; Soundararajan, R; Sphyris, N; Stephan, CC; Taube, JH; Toneff, MJ; Vijay, GV; Werden, SJ; Zhao, N | 1 |
| Furukawa, S; Ishikawa, T; Kikuchi, H; Ooka, A; Saito, SY; Yamaguchi, M | 1 |
| Jin, A; Li, B; Li, W; Xiao, D | 1 |
| Chen, J; Lan, X; Liu, X; Song, D; Xue, J; Zhang, L; Zhang, X | 1 |
| Edemir, B; Kaiser, M | 1 |
| Rolev, KD; Shu, XS; Ying, Y | 1 |
| Cui, H; Gao, L; Yang, L | 1 |
1 review(s) available for pyrroles and tws 119
| Article | Year |
|---|---|
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Astrocytes; beta Catenin; Diabetic Retinopathy; Ependymoglial Cells; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Inflammation; Microglia; Mitochondria; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroglia; Neuroprotective Agents; Oxidative Stress; Pyrimidines; Pyrroles; Retinal Ganglion Cells; RNAi Therapeutics; tau Proteins | 2021 |
21 other study(ies) available for pyrroles and tws 119
| Article | Year |
|---|---|
Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells.
Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Forkhead Box Protein O1; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Humans; Paired Box Transcription Factors; PAX3 Transcription Factor; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rhabdomyosarcoma, Alveolar | 2010 |
GSK-3β negatively regulates megakaryocyte differentiation and platelet production from primary human bone marrow cells in vitro.
Topics: Blood Platelets; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Down-Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; MAP Kinase Signaling System; Megakaryocytes; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Pyrroles; Thrombopoietin | 2011 |
Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes.
Topics: Cell Differentiation; Cell Proliferation; Cells, Cultured; Fetal Blood; Glycogen Synthase Kinase 3; Humans; Lymphocyte Activation; Pyrimidines; Pyrroles; Signal Transduction; T-Lymphocyte Subsets; Wnt Proteins | 2011 |
Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.
Topics: Adoptive Transfer; Apoptosis; Caspase 3; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell Survival; Cells, Cultured; Cytokines; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Lymphocyte Activation; Phenotype; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrroles; Stem Cells; Wnt Signaling Pathway | 2012 |
Wnt signaling inhibits CTL memory programming.
Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Female; Flow Cytometry; Glycogen Synthase Kinase 3; Immunologic Memory; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; L-Selectin; Lymphocyte Activation; Male; Mice; Mice, Congenic; Mice, Transgenic; Pyrimidines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Sirolimus; T-Box Domain Proteins; T-Lymphocytes, Cytotoxic; TOR Serine-Threonine Kinases; Wnt Signaling Pathway | 2013 |
Involvement of oncogenic protein β-catenin in LPS-induced cytotoxicity in mouse mononuclear leukemia RAW 264.7 cells.
Topics: Animals; beta Catenin; Cell Line; Cell Line, Tumor; Chalcones; Drug Interactions; Endoplasmic Reticulum Stress; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Leukemia; Lipopolysaccharides; Mice; Monocytes; Phosphorylation; Pyrimidines; Pyrroles; RNA, Small Interfering; Toll-Like Receptor 4; Transfection | 2013 |
[Activation of Wnt/β-catenin pathway in NK cells by glycogen synthase kinase-3β inhibitor TWS119 promotes the expression of CD62L].
Topics: beta Catenin; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Killer Cells, Natural; L-Selectin; Pyrimidines; Pyrroles; Wnt Signaling Pathway | 2015 |
Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.
Topics: Actins; Calcium-Binding Proteins; Calponins; Cell Differentiation; Cell Line; Gene Expression Regulation; Gene Knockout Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Membrane Proteins; Microfilament Proteins; Muscle Proteins; Myocytes, Smooth Muscle; Nuclear Proteins; Phosphoproteins; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Recombinant Proteins; RNA, Small Interfering; Serine; Thiazoles; Threonine; Trans-Activators; Urea | 2016 |
GSK-3β inhibitor TWS119 attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Claudin-3; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Permeability; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Stroke; Tissue Plasminogen Activator; Wnt Signaling Pathway; Zonula Occludens-1 Protein | 2016 |
Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T Cells.
Topics: Animals; CD4-Positive T-Lymphocytes; Cells, Cultured; Female; Humans; Immunologic Memory; Lymphopoiesis; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Precursor Cells, T-Lymphoid; Pyrimidines; Pyrroles; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling.
Topics: Animals; beta Catenin; Cell Adhesion Molecules; Connexin 43; Connexins; Fibrosis; Gap Junctions; Heart; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Up-Regulation; Ventricular Remodeling; Wnt Signaling Pathway | 2017 |
GSK-3β as a target for protection against transient cerebral ischemia.
Topics: Animals; beta Catenin; Blood-Brain Barrier; Brain; Disease Models, Animal; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Humans; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Pyrimidines; Pyrroles; Rats; Stroke; Wnt Signaling Pathway; Zonula Occludens-1 Protein | 2017 |
Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer.
Topics: Animals; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Cytotoxicity, Immunologic; Female; HCT116 Cells; Humans; Immunotherapy, Adoptive; Intraepithelial Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Pyrimidines; Pyrroles; Up-Regulation; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2018 |
Effects of Glycogen Synthase Kinase-3β Inhibitor TWS119 on Proliferation and Cytokine Production of TILs From Human Lung Cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; CD8-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Cytokines; Female; Glycogen Synthase Kinase 3 beta; Humans; Immunologic Memory; Immunotherapy, Adoptive; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Pyrimidines; Pyrroles; Wnt Signaling Pathway | 2018 |
Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation.
Topics: Animals; beta Catenin; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Glucose; Glycogen Synthase Kinase 3 beta; Humans; Matrix Metalloproteinase 9; Mice; Peritoneal Dialysis; Peritoneal Fibrosis; Peritoneum; Phosphorylation; Pyrimidines; Pyrroles; Snail Family Transcription Factors; Tamoxifen | 2018 |
GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.
Topics: Cell Line, Tumor; Cell Movement; Datasets as Topic; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Female; Glycogen Synthase Kinase 3 beta; Humans; Inhibitory Concentration 50; Lithium Chloride; Neoplastic Stem Cells; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Survival Analysis; Triple Negative Breast Neoplasms; Wnt Signaling Pathway | 2019 |
Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation.
Topics: Active Transport, Cell Nucleus; Adenine; Animals; Antineoplastic Agents; beta Catenin; Cell Differentiation; Cell Transdifferentiation; Dictyostelium; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta; Hepatic Stellate Cells; Hexanones; Liver Cirrhosis; Mice; Oxadiazoles; Phosphorylation; Pyrimidines; Pyrroles; Quinoxalines; Signal Transduction | 2019 |
PHLPP2 downregulation protects cardiomyocytes against hypoxia-induced injury through reinforcing Nrf2/ARE antioxidant signaling.
Topics: Animals; Antioxidant Response Elements; Apoptosis; Cell Hypoxia; Cell Survival; Down-Regulation; Glycogen Synthase Kinase 3 beta; Mice; Myocytes, Cardiac; NF-E2-Related Factor 2; Phosphoprotein Phosphatases; Phosphorylation; Pyrimidines; Pyrroles; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction | 2019 |
Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Microglia; Pyrimidines; Pyrroles; Recovery of Function; Stroke; Wnt Signaling Pathway | 2019 |
Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms.
Topics: Animals; Aquaporin 2; Aquaporin 3; Aquaporin 4; Cells, Cultured; Chloroquine; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Female; Glycogen Synthase Kinase 3; Indoles; Kidney Tubules, Collecting; Leupeptins; Lithium Chloride; Macrolides; Maleimides; Protein Kinase Inhibitors; Proteolysis; Pyrimidines; Pyrroles; Rats, Wistar; RNA, Messenger | 2020 |
GSK-3β inhibitor TWS119 alleviates hypoxic-ischemic brain damage via a crosstalk with Wnt and Notch signaling pathways in neonatal rats.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Female; Glycogen Synthase Kinase 3 beta; Hypoxia-Ischemia, Brain; Male; Models, Animal; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Wnt Signaling Pathway | 2021 |