pyrroles has been researched along with su 5402 in 178 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (1.69) | 18.2507 |
| 2000's | 96 (53.93) | 29.6817 |
| 2010's | 75 (42.13) | 24.3611 |
| 2020's | 4 (2.25) | 2.80 |
| Authors | Studies |
|---|---|
| Hirth, P; Hubbard, SR; McMahon, G; Mohammadi, M; Schlessinger, J; Sun, L; Tang, C; Yeh, BK | 1 |
| Elbaum, D; Lydon, NB; Toledo, LM | 1 |
| Gunther, EC; McCabe, KL; Reh, TA | 1 |
| Keating, MT; McMahon, G; Nechiporuk, A; Poss, KD; Shen, J; Thisse, B; Thisse, C | 1 |
| Carter, E; Longley, BJ; Ma, Y; McMahon, G | 1 |
| Doherty, P; Facci, L; Kee, WJ; Macdonald, G; Skaper, SD; Walsh, FS | 1 |
| Bowden, GT; Klein, RD; Maliner, MS; Nagle, RB; Udayakumar, TS | 1 |
| Hayashi, H; Imamura, T; Ishisaki, A; Suzuki, M | 1 |
| Davies, PD; Del Rio-Tsonis, K; Duncan, G; Marcantonio, JM; McMahon, G; Tamiya, S; Wormstone, IM | 1 |
| Edlund, T; Jessell, TM; Nusse, R; Rydström, A; Trimborn, T; Willert, K; Wilson, SI | 1 |
| Makabe, KW; Minokawa, T; Nishida, H; Yagi, K | 1 |
| Kim, GJ; Nishida, H | 1 |
| Koshida, S; Kuroiwa, A; Sawada, A; Shinya, M; Takeda, H | 1 |
| Allen, SL; Bentley, M; Brody, JP; Carnicero, F; Cross, NC; Demiroglu, A; Doody, ML; Goldman, JM; Hawson, G; Heath, C; Koduru, P; Melo, JV; Reiter, A; Rodwell, R; Steer, EJ; Taylor, K | 1 |
| Mandler, M; Neubüser, A | 1 |
| Jacques, BE; Kelley, MW; Mueller, KL | 1 |
| Ho, S; Hoffman, MP; Kidder, BL; Kleinman, HK; Lakhani, S; Larsen, M; Steinberg, ZL | 1 |
| Beebe, DC; Feldmeier, M; Huang, JX; Shui, YB | 1 |
| Heryanto, B; Lipson, KE; Rogers, PA | 1 |
| Itoh, N; Konishi, M; Mikami, T; Miyake, A; Ohmachi, S | 1 |
| Edlund, T; Gunhaga, L; Hsieh, JC; Jessell, TM; Marklund, M; Sjödal, M | 1 |
| Dickinson, RJ; Eblaghie, MC; Farrell, ER; Keyse, SM; Lunn, JS; Mathers, J; Münsterberg, AE; Sanz-Ezquerro, JJ; Storey, K; Tickle, C | 1 |
| Coco, L; Dell'Era, P; Metra, M; Nicoli, S; Presta, M; Ronca, R | 1 |
| Bair, EL; Bowden, GT; Nagle, RB; Udayakumar, TS | 1 |
| Griffin, KJ; Kimelman, D | 1 |
| Roy, NM; Sagerström, CG | 1 |
| Chang, H; Li, Z; Masih-Khan, E; Paterson, JL; Pollett, JB; Stewart, AK; Trudel, S; Wen, XY | 1 |
| Kintner, C; Moreno, TA | 1 |
| Cha, SW; Chae, JP; Daar, I; Hwang, YS; Kim, J; Lee, HS; Lee, SY; Park, MJ | 1 |
| Chase, AJ; Cross, NC; Grand, EK; Heath, C; Rahemtulla, A | 1 |
| Berezin, V; Bock, E; Cambon, K; Hansen, SM; Herrero, AI; Sandi, C; Skibo, G; Venero, C | 1 |
| Gill, JC; Moenter, SM; Tsai, PS | 1 |
| Akita, K; Eblaghie, MC; Jung, HS; Kim, JY; Song, SJ; Tickle, C | 1 |
| Brigande, JV; Chang, W; Fekete, DM; Wu, DK | 1 |
| Chandrasekhar, A; Concha, ML; Dong, W; Higashi, K; Hiraga, T; Holder, N; Regan, J; Russell, C; Take-Uchi, M; Teraoka, H; Wilson, SW; Yokoyama, R | 1 |
| Chung, HA; Hyodo-Miura, J; Kitayama, A; Nagamune, T; Terasaka, C; Ueno, N | 1 |
| Daemen, MJ; Dassen, WR; De Windt, LJ; Doevendans, PA; Heeneman, S; Palmen, M; Van Bilsen, M; Willems, J; Zimmermann, R | 1 |
| Draper, BW; Jackman, WR; Stock, DW | 1 |
| Delaune, E; Kodjabachian, L; Lemaire, P | 1 |
| Araki, M; Ikegami, Y; Mitsuda, S; Yoshii, C | 1 |
| Ishimaru, Y; Kasahara, M; Morohashi, K; Noce, T; Sugiyama, N; Tsunekawa, N; Yoshioka, H | 1 |
| Aoyama, T; Ishibe, T; Katagiri, T; Nagayama, S; Nakamura, T; Nakamura, Y; Nakayama, T; Nishijo, K; Okamoto, T; Shibata, KR; Shima, Y; Toguchida, J | 1 |
| Chung, HA; Hyodo-Miura, J; Nagamune, T; Ueno, N | 1 |
| Dvorak, P; Dvorakova, D; Hampl, A; Koskova, S; Krekac, D; Najvirtova, M; Vodinska, M | 1 |
| Kwan, W; Liu, S; Lubieniecka, JM; Nielsen, TO; Terry, J | 1 |
| Birnbaum, D; Chevrier, V; Daviet, L; Delaval, B; Dubreuil, P; Lelièvre, H; Létard, S | 1 |
| Beer, N; Dodt, J; Etscheid, M | 1 |
| Abe, K; Akasaka, Y; Inoue, H; Sato, T | 1 |
| Berezin, VA; Bock, E; Dmitrieva, O; Klementiev, B; Lushnikova, IV; Novikova, T; Skibo, GG; Vaudano, E; Voronin, KY | 1 |
| Molyneaux, K; Runyan, C; Schaible, K; Takeuchi, Y; Wylie, C | 1 |
| Bernard-Pierrot, I; Brams, A; Caillault, A; Cappellen, D; Chopin, D; Diez de Medina, SG; Dunois-Lardé, C; Graff, G; Radvanyi, F; Ricol, D; Thiery, JP | 1 |
| Groves, AK; Martin, K | 1 |
| Hirasawa, N; Kuramasu, A; Miyoshi, I; Numata, Y; Ohtsu, H; Okuyama, R; Sugiura, Y; Tagami, H; Terui, T; Watanabe, T | 1 |
| Acampora, D; Bally-Cuif, L; Foucher, I; Houart, C; Mione, M; Simeone, A | 1 |
| Ang, SL; Bian, W; Chen, YG; Jing, N; Lin, W; Liu, L; Wang, C; Xia, C | 1 |
| Agrotis, A; Bobik, A; Jennings, G; Kanellakis, P; Pomilio, G; Raj, T | 1 |
| Berezin, V; Billestrup, N; Bock, E; Heding, P; Li, S; Mandrup-Poulsen, T; Petersen, LG; Saldeen, J; Størling, J | 1 |
| Altmann, CR; Raible, DW; Ungos, JM; Urban, AE; Vize, PD; Zhou, X | 1 |
| Courty, J; Hatziapostolou, M; Katsoris, P; Papadimitriou, E; Polytarchou, C | 1 |
| Doi, K; Hibi, M; Kikuchi, Y; Nikaido, M; Shimizu, T; Yamasu, K | 1 |
| Belluardo, N; Fuxe, K; Mauro, A; Mudò, G | 1 |
| Abe, G; Ide, H; Tamura, K | 1 |
| Metzger, DE; Shannon, JM; Xu, Y | 1 |
| Asai, K; Ito, J; Kheirollah, A; Lu, R; Miura, Y; Nagayasu, Y; Nakaya, S; Nishida, T; Okumura-Noji, K; Yokoyama, S | 1 |
| Diaz, FJ; Eppig, JJ; Matzuk, MM; O'Brien, MJ; Pangas, SA; Sharma, S; Shimasaki, S; Su, YQ; Sugiura, K; Wigglesworth, K | 1 |
| Deng, CX; Kageyama, R; Liu, T; Masamizu, Y; Nakayama, R; Niwa, Y | 1 |
| Allen, S; Dhoot, GK; Zhao, W | 1 |
| Dai, Y; Fukuoka, T; Kobayashi, K; Noguchi, K; Obata, K; Yamanaka, H | 1 |
| Cleaver, D; Patient, R; Walmsley, M | 1 |
| Agasse, F; Benzakour, O; Coronas, V; Jaber, M; Nicoleau, C; Petit, J; Roger, M | 1 |
| Bolitho, C; Xu, W; Zoellner, H | 1 |
| Liedtke, D; Winkler, C | 1 |
| Berezin, V; Bock, E; Christensen, C; Kiselyov, VV; Køhler, LB; Li, S | 2 |
| Ikeda, K; Matsui, H; Nakajima, Y; Sakabe, M; Sakata, H; Yamagishi, T; Yanagawa, N | 1 |
| Cole, GJ; Kim, MJ; Liu, IH; Zhang, C | 1 |
| Fletcher, RB; Harland, RM | 1 |
| Fu, KK; Geetha-Loganathan, P; Nimmagadda, S; Richman, JM; Szabo-Rogers, HL | 1 |
| Bermingham-McDonogh, O; Hayashi, T; Ray, CA | 1 |
| Ferrer-Vaquer, A; Firnberg, N; Leibbrandt, A; Maurey, P; Neubüser, A; Werzowa, J | 1 |
| Nechiporuk, A; Raible, DW | 1 |
| Lee, Y; Marques, SR; Poss, KD; Yelon, D | 1 |
| Fischer, AJ; Scott, MA; Tuten, W | 1 |
| Bally-Cuif, L; Becker, TS; Kapsimali, M; Komisarczuk, AZ; Stigloher, C; Topp, S | 1 |
| Bachmann, AW; Hutley, LJ; Newell, FS; Prins, JB; Ramnoruth, SN; Spelta, MC; Whitehead, JP; Widberg, CH | 1 |
| Bae, YC; Cha, SW; Chae, JP; Cho, HJ; Hwang, YS; Kim, DS; Lee, JW; Park, KM; Park, MJ | 1 |
| Iyengar, L; Lovicu, FJ; McAvoy, JW; Patkunanathan, B | 1 |
| Agudo, M; Connor, S; Corcoran, JP; Goncalves, MB; Maden, M; McMahon, S; Minger, SL | 1 |
| Firth, JD; Li, M; Putnins, EE | 1 |
| Bibonne, A; Leclerc, C; Lee, KW; Moreau, M; Néant, I | 1 |
| Ameri, J; Johannesson, M; Norrman, K; Sand, FW; Semb, H; Ståhlberg, A | 1 |
| Mizushima, S; Murakami, F; Takashima, S; Tamada, A; Yamamoto, N; Yamauchi, K | 1 |
| Bayha, E; Grapin-Botton, A; Jørgensen, MC; Serup, P | 1 |
| Hammond, AJ; Hunter, M; Hunter, MG; Mann, GE; Robinson, RS; Woad, KJ | 1 |
| Biffi, A; Buono, M; Capotondo, A; Cosma, MP; Naldini, L; Plati, T; Visigalli, I | 1 |
| Nichols, J; Roode, M; Silva, J; Smith, A | 1 |
| Goda, T; Takagi, C; Ueno, N | 1 |
| Andreasen, EA; Franzosa, JA; La Du, J; Mathew, LK; Perry, J; Sengupta, S; Tanguay, RL | 1 |
| Akaike, A; Kihara, T; Niidome, T; Nonaka, H; Sugimoto, H | 1 |
| Atkinson-Leadbeater, K; Bertolesi, GE; Cechmanek, PB; Hehr, CL; McFarlane, S; Webber, CA | 1 |
| Amann, T; Bataille, F; Bosserhoff, AK; Dettmer, K; Hellerbrand, C; Kiefer, P; Liedtke, C; Mühlbauer, M; Oefner, PJ; Spruss, T; Trautwein, C; Wild, P | 1 |
| Abe, S; Aizawa, S; Kaneko, M; Kiyonari, H | 1 |
| Conlon, FL; Doherty, JT; Mack, CP; Taylor, JM | 1 |
| Bergamasco, R; Biffi, A; Buono, M; Cosma, MP; Visigalli, I | 1 |
| Cheung, LW; Leung, KW; Wong, AS; Wong, CK; Wong, RN | 1 |
| De Castro, F; Esteban, PF; García-González, D; Murcia-Belmonte, V | 1 |
| Aman, A; Nguyen, M; Piotrowski, T | 1 |
| Matsuzaki, T; Misawa, M; Muramatsu, T; Sakurai, T; Sato, M; Watanabe, S | 1 |
| Chester, JD; Cooper, PA; Knowles, MA; Lamont, FR; Shnyder, SD; Tomlinson, DC | 1 |
| Ealy, AD; Fields, SD; Hansen, PJ | 1 |
| Dale, JK; Hyttel, P; Serup, P; Winzi, MK | 1 |
| Cheng, YB; Dai, G; Geng, MY; Li, J; Qi, X | 1 |
| Decker, JR; Hutson, MR; Kirby, ML; Kuhn, EB; Kuhn, EN; Pegram, K; Sato, A; Scholl, AM; Stadt, HA | 1 |
| Lazic, S; Scott, IC | 1 |
| Nakajima, Y; Sakabe, M; Sakata, H; Yamagishi, T; Yanagawa, N | 1 |
| Fujita-Hamabe, W; Nakamoto, K; Tokuyama, S | 1 |
| Beule, A; Hosemann, W; Kaftan, H; Miehe, B; Reuther, L | 1 |
| Ros, MA; Roselló-Díez, A; Torres, M | 1 |
| Hammond, KL; Whitfield, TT | 1 |
| Filipek-Gorniok, B; Fischer, S; Ledin, J | 1 |
| Huang, CT; Lavaute, TM; Yoo, YD; Zhang, SC; Zhang, X | 1 |
| Hammond, AJ; Hunter, MG; Laird, M; Mann, GE; Robinson, RS; Woad, KJ | 1 |
| Arenzana, FJ; Clemente, D; de Castro, F; Ortega, MC | 1 |
| Chauhan, MS; George, A; Kamble, NM; Manik, RS; Palta, P; Sharma, R; Singh, KP; Singla, SK | 1 |
| Funae, Y; Hikita, Y; Iwao, H; Izumi, Y; Kawamoto, Y; Kusakabe, H; Miura, K; Nakao, T; Shiota, M; Tanaka, M | 1 |
| García-Castro, MI; Stuhlmiller, TJ | 1 |
| Asakawa, A; Asakawa, T; Chosa, N; Hasegawa, T; Ishisaki, A; Mitome, M; Tanaka, M; Yoshimura, Y | 1 |
| Ealy, AD; Zhang, K | 1 |
| Han, C; Liao, S; Wang, S; Wang, X; Wu, Y; Zhang, Y | 1 |
| Hu, D; Marcucio, RS | 1 |
| Asakawa, T; Chosa, N; Fujihara, Y; Hasegawa, T; Ishisaki, A; Kitamura, T; Mitome, M; Tanaka, M; Yoshimura, Y | 1 |
| Banasr, M; Duman, RS; Duric, V; Elsayed, M; Fournier, NM; Licznerski, P | 1 |
| Dabdoub, A; Jacques, BE; Kelley, MW | 1 |
| Currie, PD; Goldshmit, Y; Hall, TE; Jusuf, PR; Nguyen-Chi, M; Sztal, TE | 1 |
| Al-awar, R; Fladd, C; Jiang, C; Nguyen, L; Prakesch, M; Rotin, D; Trzcinska-Daneluti, AM; Uehling, D | 1 |
| Adjaye, J; Bhushan, R; Fauler, B; Lehrach, H; Sudheer, S | 1 |
| Bilsland, J; Cao, L; Chambers, SM; Lee, G; Mica, Y; Niu, L; Qi, Y; Shi, SH; Stevens, E; Studer, L; Whiting, P; Zhang, XJ | 1 |
| Esliger, A; Hurley, MM; Xiao, L | 1 |
| Akil, H; Turner, CA; Watson, SJ | 1 |
| Chen, L; Fukuda, T; Hirohata, S; Jin, G; Kasai, T; Kudoh, T; Mizutani, A; Murakami, H; Nakanishi, K; Salomon, DS; Seno, M; Yan, T | 1 |
| Kwon, HJ | 1 |
| Holland, MK; Khodadadi, K; Pashaiasl, M; Richings, NM; Verma, PJ | 1 |
| Arcaro, A; Bodmer, N; Cwiek, P; Djonov, V; Ghosal, A; Gross, N; Höland, K; Largey, F; Lucia Buccarello, A; Salm, F; Schäfer, SC; Styp-Rekowska, B; Westermann, F; Wotzkow, C; Zlobec, I | 1 |
| Kim, J; Ma, T | 1 |
| Akagawa, Y; Gong, P; Morita, K; Shiba, T; Sun, N; Yang, L; Yuan, Q; Zou, H | 1 |
| Hunter, MG; Laird, M; Mann, GE; Robinson, RS; Woad, KJ | 1 |
| Jiang, YJ; Lin, BF; Liu, DW; Tsai, SM; Wang, WP | 1 |
| Hashiguchi, M; Mullins, MC | 1 |
| Buchholz, DE; Clegg, DO; Coffey, PJ; Croze, RH; Hinman, CR; Pennington, BO | 1 |
| Chang, KW; Huang, BM; Huang, YL; Ju, TK; Su, PH; Wong, ZR; Yang, HY | 1 |
| Chien, CB; Dorsky, RI; Eriksson, I; Kjellén, L; Kojima, A; Koketsu, M; Kuberan, B; Loganathan, D; Nguyen, TK; Sorna, V; Tran, VM | 1 |
| Cattell, MV; Cerny, R; Hawkins, MB; Jandzik, D; Medeiros, DM; Square, TA | 1 |
| Christin Eder, M; Hasse, C; Hassel, M; Hobmayer, B; Holz, O; Lange, E; Pisowodzki, L; Rebscher, N | 1 |
| Kawakami, M; Kirita, T; Morita, S; Nochioka, K; Okuda, H; Shimomura, T; Tatsumi, K; Wanaka, A | 1 |
| Akiyama, N; Ikeda, T; Kohno, M; Koji, T; Shibata, Y; Takahashi, H; Yamamoto-Fukuda, T | 1 |
| Augustin, HG; Hecker, M; Heiss, M; Hellström, M; Kalén, M; Korff, T; May, T; Weber, H | 1 |
| Chapman, SC; Ray, P | 1 |
| Kanai, Y; Matsukawa, S; Michiue, T; Watanabe, T | 1 |
| Kalajzic, I; Maye, P; Mina, M; Sagomonyants, K | 2 |
| Balek, L; Buchtova, M; Dosedelova, H; Gudernova, I; Jelinkova, I; Kozubik, A; Krejci, P; Kunova, M; Pivnicka, J; Roubalova, L; Vesela, I | 1 |
| Cooper, HJ; Creese, AJ; Cunningham, DL; Heath, JK; Zhao, H | 1 |
| Ago, T; Arimura, K; Kamouchi, M; Kitazono, T; Kuroda, J; Makihara, N; Nakamura, K; Nishimura, A; Ooboshi, H; Tachibana, M; Wakisaka, Y; Yoshikawa, Y | 1 |
| Jaroonwitchawan, T; Muangchan, P; Noisa, P | 1 |
| Fukui, M; Itoyama, T; Kawaguchi, M; Kawara, M; Kitamura, SI; Kurokawa, D; Murakami, Y; Nakayama, K; Sugahara, Y | 1 |
| Chae, SW; Cho, GJ; Go, YY; Kim, SE; Song, JJ | 1 |
| Anderton, H; Brameld, JM; Mohammed, RH; Sweetman, D | 1 |
| Ghosh, P; Maurer, JM; Sagerström, CG | 1 |
| Cattini, PA; Dolinsky, VW; Kardami, E; Wang, J; Xiang, B | 1 |
| Bouloux, PM; Butts, T; Graham, A; Hu, Y; Poopalasundaram, S | 1 |
| Chen, M; Cheng, J; Geng, D; Li, CF; Liu, Q; Yi, LT; Zhang, QP; Zhu, JX | 1 |
| Ghaskadbi, S; Turwankar, A | 1 |
| Frederiksen, H; Harpelunde Poulsen, K; Juul Hare, K; Juul, A; Jørgensen, A; Langhoff Thuesen, L; Lundvall, L; Melau, C; Mitchell, RT; Nielsen, JE; Perlman, S; Rajpert-De Meyts, E | 1 |
| Akaike, T; Kuga, K; Kusakari, Y; Minamisawa, S; Semba, K; Uesugi, K; Urashima, T | 1 |
| Chen, P; Huang, X; Wu, M; Yang, S; Zhang, L; Zhang, Y | 1 |
| Andrikou, C; Hejnol, A | 1 |
| Carballo, L; Czarkwiani, A; Dylus, DV; Oliveri, P | 1 |
2 review(s) available for pyrroles and su 5402
| Article | Year |
|---|---|
The structure-based design of ATP-site directed protein kinase inhibitors.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Anthraquinones; Binding Sites; Catalytic Domain; Cyclin-Dependent Kinases; Drug Design; Enzyme Inhibitors; Humans; Kinetin; Piperazines; Protein-Tyrosine Kinases; Purines; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Receptors, Growth Factor; Roscovitine; Staurosporine; Structure-Activity Relationship | 1999 |
New approaches to therapy for mastocytosis. A case for treatment with kit kinase inhibitors.
Topics: Amino Acid Substitution; Combined Modality Therapy; Drug Design; Enzyme Activation; Enzyme Inhibitors; Feasibility Studies; Humans; Indoles; Ligands; Mast Cells; Mastocytosis; Piperazines; Point Mutation; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Pyrroles; Stem Cell Factor | 2000 |
176 other study(ies) available for pyrroles and su 5402
| Article | Year |
|---|---|
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
Topics: 3T3 Cells; Adenosine Triphosphate; Amino Acid Sequence; Animals; Crystallography, X-Ray; Enzyme Inhibitors; ErbB Receptors; Hydrogen Bonding; Mice; Models, Molecular; Phosphorylation; Phosphotyrosine; Piperazines; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Insulin; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor | 1997 |
The development of the pattern of retinal ganglion cells in the chick retina: mechanisms that control differentiation.
Topics: 3T3 Cells; Animals; Cell Differentiation; Chick Embryo; Enzyme Inhibitors; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Mice; Mitosis; Neurofilament Proteins; Pyrroles; Receptors, Fibroblast Growth Factor; Retina; Retinal Ganglion Cells; Stem Cells; Time Factors; Tubulin | 1999 |
Roles for Fgf signaling during zebrafish fin regeneration.
Topics: Amputation, Surgical; Animals; Enzyme Inhibitors; Epidermis; Extremities; Fibroblast Growth Factors; Mesoderm; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Regeneration; Signal Transduction; Zebrafish | 2000 |
The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Chick Embryo; Ciliary Neurotrophic Factor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glial Cell Line-Derived Neurotrophic Factor; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Sensitivity and Specificity | 2000 |
Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors.
Topics: Dimerization; Enzyme Precursors; Epithelial Cells; Fibroblast Growth Factors; Humans; Male; Metalloendopeptidases; Prostate; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Transfection; Tumor Cells, Cultured | 2001 |
BMP-2 augments FGF-induced differentiation of PC12 cells through upregulation of FGF receptor-1 expression.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurites; PC12 Cells; Peptides; Pyrroles; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; RNA, Messenger; Signal Transduction; Smad7 Protein; Trans-Activators; Transforming Growth Factor beta; Up-Regulation | 2001 |
FGF: an autocrine regulator of human lens cell growth independent of added stimuli.
Topics: Autocrine Communication; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblast Growth Factor 2; Fluorescent Antibody Technique, Indirect; Humans; Lens Capsule, Crystalline; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
The status of Wnt signalling regulates neural and epidermal fates in the chick embryo.
Topics: Animals; Biomarkers; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Carrier Proteins; Cell Differentiation; Cell Lineage; Cells, Cultured; Chick Embryo; Ectoderm; Embryonic Induction; Epidermal Cells; Epidermis; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Immunohistochemistry; Models, Biological; Neurons; Proteins; Proto-Oncogene Proteins; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; RNA, Messenger; Signal Transduction; Transcription Factors; Wnt Proteins; Xenopus Proteins; Zebrafish Proteins | 2001 |
Binary specification of nerve cord and notochord cell fates in ascidian embryos.
Topics: Animals; Blastomeres; Butadienes; Cell Differentiation; Central Nervous System; Fibroblast Growth Factor 2; Mitogen-Activated Protein Kinases; Nitriles; Notochord; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Urochordata | 2001 |
Role of the FGF and MEK signaling pathway in the ascidian embryo.
Topics: Animals; Blotting, Western; Butadienes; Ectoderm; Endoderm; Enzyme Inhibitors; Fibroblast Growth Factors; Growth Substances; Mesoderm; Mitogen-Activated Protein Kinases; Nitriles; Notochord; Protein Serine-Threonine Kinases; Pyrroles; Signal Transduction; Time Factors; Tissue Distribution; Urochordata | 2001 |
Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon in zebrafish embryos.
Topics: Animals; Body Patterning; Central Nervous System; DNA, Antisense; Embryo, Nonmammalian; Enzyme Inhibitors; Female; Fibroblast Growth Factor 3; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Genes, Dominant; Genes, ras; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mutation; Proto-Oncogene Proteins; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Telencephalon; Zebrafish; Zebrafish Proteins | 2001 |
The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins.
Topics: Aged; Amino Acid Sequence; Base Sequence; Cell Division; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 8; Enzyme Inhibitors; Female; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Molecular Sequence Data; Oncogene Proteins; Oncogene Proteins, Fusion; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transfection; Translocation, Genetic | 2001 |
FGF signaling is necessary for the specification of the odontogenic mesenchyme.
Topics: Animals; Body Patterning; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Cell Cycle Proteins; Culture Techniques; Cytokines; DNA-Binding Proteins; Ectoderm; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hedgehog Proteins; Homeobox Protein PITX2; Homeodomain Proteins; In Situ Hybridization; Incisor; LIM-Homeodomain Proteins; Mesoderm; Mice; Molar; Nerve Tissue Proteins; Nuclear Proteins; Odontogenesis; PAX9 Transcription Factor; Proteins; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Trans-Activators; Transcription Factors | 2001 |
Fibroblast growth factor signaling regulates pillar cell development in the organ of corti.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fibroblast Growth Factors; Hair Cells, Auditory, Inner; Mice; Mice, Inbred ICR; Morphogenesis; Organ of Corti; Protein-Tyrosine Kinases; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Receptor, Nerve Growth Factor; Receptors, Fibroblast Growth Factor; Receptors, Nerve Growth Factor; Signal Transduction; Stem Cells | 2002 |
Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.
Topics: Animals; Apoptosis; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Division; Dose-Response Relationship, Drug; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Mesoderm; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Organ Culture Techniques; Protein Isoforms; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Submandibular Gland; Time Factors; Transforming Growth Factor beta | 2002 |
Evaluation of fibroblast growth factor signaling during lens fiber cell differentiation.
Topics: Animals; Blotting, Western; Cattle; Cell Differentiation; Cell Division; Chick Embryo; Defective Viruses; Enzyme Inhibitors; Epithelial Cells; Fibroblast Growth Factor 1; Fibroblast Growth Factors; Genetic Vectors; Lens, Crystalline; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Vitreous Body | 2003 |
Effect of angiogenesis inhibitors on oestrogen-mediated endometrial endothelial cell proliferation in the ovariectomized mouse.
Topics: Angiogenesis Inhibitors; Animals; Cell Division; Endometrium; Endothelial Growth Factors; Endothelium, Vascular; Estrogens; Female; Fibroblast Growth Factors; Immune Sera; Indoles; Intercellular Signaling Peptides and Proteins; Lymphokines; Mice; Mice, Inbred Strains; Ovariectomy; Platelet-Derived Growth Factor; Progesterone; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2003 |
Preferential neurotrophic activity of fibroblast growth factor-20 for dopaminergic neurons through fibroblast growth factor receptor-1c.
Topics: Animals; Cell Survival; Cells, Cultured; Dopamine; Enzyme Inhibitors; Fibroblast Growth Factors; Flavonoids; In Situ Hybridization; Mesencephalon; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; RNA, Messenger; Signal Transduction | 2003 |
Specification of dorsal telencephalic character by sequential Wnt and FGF signaling.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Bone Morphogenetic Proteins; Cell Differentiation; Chick Embryo; Ectoderm; Embryonic Induction; Epithelium; Eye Proteins; Fibroblast Growth Factors; Frizzled Receptors; Gene Expression Regulation, Developmental; Homeodomain Proteins; Immunohistochemistry; In Situ Hybridization; Mice; Nerve Tissue Proteins; Organ Culture Techniques; Paired Box Transcription Factors; PAX6 Transcription Factor; Proteins; Proto-Oncogene Proteins; Pyrroles; Receptors, Fibroblast Growth Factor; Repressor Proteins; Signal Transduction; Stem Cells; Telencephalon; Transcription Factors; Wnt Proteins; Zebrafish Proteins | 2003 |
Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
Topics: Animals; Blotting, Western; Chick Embryo; DNA Primers; Dual Specificity Phosphatase 6; Electroporation; Feedback, Physiological; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Heparin; Immunohistochemistry; In Situ Hybridization; Limb Buds; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Protein Tyrosine Phosphatases; Pyrroles; Signal Transduction | 2003 |
Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development.
Topics: Animals; Butadienes; Cell Differentiation; Cell Size; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Mesoderm; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Myosin Heavy Chains; Nitriles; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Xenopus Proteins | 2003 |
Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression.
Topics: Animals; Carcinoma; Enzyme Precursors; Humans; Male; Metalloendopeptidases; Mice; Mice, Nude; Neoplasm Transplantation; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrroles; Receptors, Fibroblast Growth Factor; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development.
Topics: Animals; Fetal Proteins; Fibroblast Growth Factor 8; Fibroblast Growth Factors; GPI-Linked Proteins; Homeodomain Proteins; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mesoderm; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; T-Box Domain Proteins; Transcription Factors; Xenopus Proteins; Zebrafish; Zebrafish Proteins | 2003 |
An early Fgf signal required for gene expression in the zebrafish hindbrain primordium.
Topics: Animals; Body Patterning; Cells, Cultured; Cycloheximide; DNA-Binding Proteins; Embryo, Nonmammalian; Fibroblast Growth Factors; Gastrula; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; Mesoderm; Microinjections; Mitogen-Activated Protein Kinases; Neurons; Oligonucleotides, Antisense; Organizers, Embryonic; Protein Synthesis Inhibitors; Pyrroles; Receptors, Fibroblast Growth Factor; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Rhombencephalon; RNA, Messenger; Signal Transduction; Spinal Cord; Time Factors; Tretinoin; Zebrafish; Zebrafish Proteins | 2004 |
Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Cycle; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multiple Myeloma; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Repressor Proteins; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators | 2004 |
Regulation of segmental patterning by retinoic acid signaling during Xenopus somitogenesis.
Topics: Animals; Animals, Genetically Modified; Antibodies; Body Patterning; Cells, Cultured; Cycloheximide; Drug Interactions; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Immunohistochemistry; Membrane Proteins; Models, Biological; Muscles; Naphthalenes; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Receptors, Notch; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Signal Transduction; Somites; Thy-1 Antigens; Time Factors; Transfection; Tretinoin; Xenopus; Xenopus laevis; Xenopus Proteins | 2004 |
Inhibition of FGF signaling causes expansion of the endoderm in Xenopus.
Topics: Abdomen; Animals; Body Patterning; Endoderm; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Mesoderm; Phenotype; Pyrroles; Receptors, Fibroblast Growth Factor; RNA; Signal Transduction; Xenopus laevis | 2004 |
Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.
Topics: Cell Line, Tumor; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 4; Humans; Multiple Myeloma; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Translocation, Genetic | 2004 |
A synthetic neural cell adhesion molecule mimetic peptide promotes synaptogenesis, enhances presynaptic function, and facilitates memory consolidation.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Conditioning, Classical; Emotions; Injections, Intraventricular; Male; Maze Learning; Memory; Molecular Mimicry; Molecular Sequence Data; Motor Activity; Neural Cell Adhesion Molecules; Neurons; Peptides; Presynaptic Terminals; Pyrroles; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Synapses; Synaptic Transmission | 2004 |
Developmental regulation of gonadotropin-releasing hormone neurons by fibroblast growth factor signaling.
Topics: Animals; Cells, Cultured; Female; Fibroblast Growth Factor 2; Fibroblast Growth Factors; Gonadotropin-Releasing Hormone; Mice; Mice, Inbred Strains; Neurites; Neurons; Pyrroles; Receptors, Fibroblast Growth Factor; Reproduction; Signal Transduction | 2004 |
Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos.
Topics: Animals; DNA-Binding Proteins; Dual Specificity Phosphatase 6; Female; Fibroblast Growth Factor 4; Fibroblast Growth Factor 8; Fibroblast Growth Factor 9; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; In Situ Hybridization; Lymphoid Enhancer-Binding Factor 1; Male; Mammary Glands, Animal; Mice; Mice, Inbred Strains; Organ Culture Techniques; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; T-Box Domain Proteins; Transcription Factors; Wnt Proteins | 2004 |
The development of semicircular canals in the inner ear: role of FGFs in sensory cristae.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Carrier Proteins; Cell Lineage; Chick Embryo; Ear, Inner; Fibroblast Growth Factor 10; Fibroblast Growth Factor 2; Fibroblast Growth Factor 3; Fibroblast Growth Factors; In Situ Hybridization; Models, Biological; Mutation; Phenotype; Protein Structure, Tertiary; Proteins; Pyrroles; Retroviridae; Time Factors; Transforming Growth Factor beta; Zebrafish Proteins | 2004 |
Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos.
Topics: Animals; Animals, Genetically Modified; Base Sequence; Cloning, Molecular; Embryo, Nonmammalian; Enzyme Inhibitors; Fertilization; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hedgehog Proteins; Homeodomain Proteins; In Situ Hybridization; LIM-Homeodomain Proteins; Luminescent Proteins; Nerve Tissue Proteins; Neurons; Pyrroles; Raphe Nuclei; Rod Opsins; Sequence Alignment; Serotonin; Signal Transduction; Time Factors; Trans-Activators; Transcription Factors; Tryptophan Hydroxylase; Veratrum Alkaloids; Zebrafish; Zebrafish Proteins | 2004 |
Screening of FGF target genes in Xenopus by microarray: temporal dissection of the signalling pathway using a chemical inhibitor.
Topics: Animals; Embryo, Nonmammalian; Fetal Proteins; Fibroblast Growth Factors; Gastrula; Gene Expression Profiling; In Situ Hybridization; Muscles; Oligonucleotide Array Sequence Analysis; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; T-Box Domain Proteins; Xenopus; Xenopus Proteins | 2004 |
Fibroblast growth factor-1 improves cardiac functional recovery and enhances cell survival after ischemia and reperfusion: a fibroblast growth factor receptor, protein kinase C, and tyrosine kinase-dependent mechanism.
Topics: Animals; Blotting, Western; Cell Survival; Fibroblast Growth Factor 1; Heart Ventricles; Hemodynamics; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardial Reperfusion; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Receptors, Fibroblast Growth Factor; Recovery of Function; Signal Transduction | 2004 |
Fgf signaling is required for zebrafish tooth development.
Topics: Animals; Base Sequence; Cluster Analysis; DNA, Complementary; Epithelium; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Histological Techniques; Homeodomain Proteins; In Situ Hybridization; Ligands; LIM-Homeodomain Proteins; Molecular Sequence Data; Morphogenesis; Nerve Tissue Proteins; Oligonucleotides, Antisense; Pyrroles; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Signal Transduction; Tooth; Transcription Factors; Zebrafish | 2004 |
Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition.
Topics: Animals; Bone Morphogenetic Proteins; Carrier Proteins; Ectoderm; Embryo, Nonmammalian; Epidermis; Fibroblast Growth Factors; Gastrula; In Situ Hybridization; Mesoderm; Models, Biological; Neurons; Proteins; Pyrroles; Signal Transduction; Time Factors; Tissue Distribution; Xenopus | 2005 |
Tissue interaction between the retinal pigment epithelium and the choroid triggers retinal regeneration of the newt Cynops pyrrhogaster.
Topics: Animals; Cell Differentiation; Cell Proliferation; Choroid; Female; Fibroblast Growth Factor 2; Insulin-Like Growth Factor I; Pigment Epithelium of Eye; Protein-Tyrosine Kinases; Pyrroles; Regeneration; Salamandridae; Signal Transduction; Tissue Culture Techniques; Transplants | 2005 |
Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos.
Topics: Animals; Biomarkers; Cell Proliferation; Chick Embryo; DNA-Binding Proteins; Fibroblast Growth Factor 9; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Gonads; Homeodomain Proteins; In Situ Hybridization; Mesonephros; Mice; Protein-Tyrosine Kinases; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Cytoplasmic and Nuclear; Receptors, Fibroblast Growth Factor; Sex Differentiation; Signal Transduction; Steroidogenic Factor 1; Transcription Factors | 2005 |
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Isoforms; Pyrimidines; Pyrroles; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma, Synovial; Signal Transduction; Urea; Xenograft Model Antitumor Assays | 2005 |
FGF signal regulates gastrulation cell movements and morphology through its target NRH.
Topics: Animals; Blotting, Western; Cell Movement; Cell Polarity; Fibroblast Growth Factors; Gastrula; In Situ Hybridization; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Protein Structure, Tertiary; Pseudopodia; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Receptors, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Xenopus | 2005 |
Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells.
Topics: Cell Differentiation; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblast Growth Factor 2; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Isoforms; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Fibroblast Growth Factor; Signal Transduction; Stem Cells | 2005 |
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Benzamides; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; ErbB Receptors; Flow Cytometry; Gefitinib; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Immunoblotting; Immunohistochemistry; In Situ Hybridization, Fluorescence; In Vitro Techniques; Inhibitory Concentration 50; Lactams, Macrocyclic; Piperazines; Prognosis; Pyrimidines; Pyrroles; Quinazolines; Rifabutin; Sarcoma, Synovial; Trastuzumab | 2005 |
Oncogenic tyrosine kinase of malignant hemopathy targets the centrosome.
Topics: Animals; Cell Cycle; Cell Growth Processes; Centrosome; G1 Phase; Hematopoietic Stem Cells; Mice; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Phosphorylation; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; S Phase | 2005 |
The hyaluronan-binding protease upregulates ERK1/2 and PI3K/Akt signalling pathways in fibroblasts and stimulates cell proliferation and migration.
Topics: Androstadienes; Butadienes; Cell Line; Cell Movement; Cell Proliferation; Culture Media, Conditioned; Fibroblasts; Humans; Lung; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrroles; Serine Endopeptidases; Skin; Time Factors; Up-Regulation; Wortmannin | 2005 |
Regulation of neurokinin-1 receptor messenger RNA expression in synovial fibroblasts of patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Fibroblast Growth Factors; Fibroblasts; Humans; Interleukin-1; Protein Isoforms; Pyrroles; Receptors, Neurokinin-1; Receptors, Neurokinin-2; RNA, Messenger; Synovial Membrane; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2005 |
A synthetic NCAM-derived peptide, FGL, protects hippocampal neurons from ischemic insult both in vitro and in vivo.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cells, Cultured; Drug Interactions; Glucose; Hippocampus; Hypoxia; Neural Cell Adhesion Molecules; Neurons; Neuroprotective Agents; Organ Culture Techniques; Phosphorylation; Propidium; Pyridinium Compounds; Pyrroles; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Synapses; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
The roles of FGF signaling in germ cell migration in the mouse.
Topics: Alternative Splicing; Animals; Cell Count; Cell Movement; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblast Growth Factor 2; Fibroblast Growth Factor 7; Germ Cells; In Vitro Techniques; Male; Mice; Mice, Transgenic; Mutation; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction | 2005 |
Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b.
Topics: Animals; Cell Transformation, Neoplastic; DNA Mutational Analysis; Epithelial Cells; Female; Fibroblasts; Humans; Mice; Mice, Nude; Protein Isoforms; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection; Transplantation, Heterologous; Urinary Bladder Neoplasms | 2006 |
Competence of cranial ectoderm to respond to Fgf signaling suggests a two-step model of otic placode induction.
Topics: Animals; Biomarkers; Chickens; Ear, Inner; Ectoderm; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Models, Biological; Pyrroles; Quail; Signal Transduction; Skull; Up-Regulation | 2006 |
The accelerating effect of histamine on the cutaneous wound-healing process through the action of basic fibroblast growth factor.
Topics: Angiogenesis Inhibitors; Animals; Fibroblast Growth Factor 2; Histamine; Histidine Decarboxylase; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Neovascularization, Physiologic; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Skin; Vascular Endothelial Growth Factor A; Wound Healing | 2006 |
Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cerebellum; Embryo, Nonmammalian; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Mesencephalon; Microinjections; Mutation; Oligonucleotides, Antisense; Otx Transcription Factors; Pyrroles; Rhombencephalon; Signal Transduction; Zebrafish; Zebrafish Proteins | 2006 |
Cell aggregation-induced FGF8 elevation is essential for P19 cell neural differentiation.
Topics: Animals; Bone Morphogenetic Proteins; Carcinoma, Embryonal; Cell Aggregation; Cell Differentiation; Cell Line, Tumor; Fibroblast Growth Factor 8; Mice; Neurons; Pluripotent Stem Cells; Protein Kinase Inhibitors; Pyrroles; RNA Interference; RNA, Small Interfering; Signal Transduction; Smad6 Protein; Up-Regulation | 2006 |
Inhibition of fibroblast growth factor receptor signaling attenuates atherosclerosis in apolipoprotein E-deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Chemokines; Dietary Fats; Enzyme Inhibitors; Fibroblast Growth Factors; Glucuronosyltransferase; Hyaluronan Synthases; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Myocytes, Smooth Muscle; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Receptors, Fibroblast Growth Factor; Sinus of Valsalva; Tunica Intima; Vascular Cell Adhesion Molecule-1 | 2006 |
IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.
Topics: Animals; Cell Line; Complement C3d; Hippocampus; Insulin-Secreting Cells; Insulinoma; Interleukin-1; Neural Cell Adhesion Molecules; Neurons; Pancreatic Neoplasms; Phosphorylation; Pyrroles; Rats; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Signal Transduction; Tumor Cells, Cultured | 2006 |
FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development.
Topics: Animals; Body Patterning; Embryo, Nonmammalian; Embryonic Induction; Epithelial Cells; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hedgehog Proteins; Kidney; Mesoderm; Nephrons; Oligonucleotide Array Sequence Analysis; Pyrroles; Signal Transduction; Trans-Activators; Xenopus laevis; Xenopus Proteins | 2006 |
Heparin affin regulatory peptide/pleiotrophin mediates fibroblast growth factor 2 stimulatory effects on human prostate cancer cells.
Topics: Carrier Proteins; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Cell Movement; Cytokines; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hydrogen Peroxide; Immunologic Factors; Kinetics; Luciferases; Male; Models, Biological; Oxidants; Promoter Regions, Genetic; Prostatic Neoplasms; Pyrroles; Recombinant Proteins; RNA, Messenger | 2006 |
Initial specification of the epibranchial placode in zebrafish embryos depends on the fibroblast growth factor signal.
Topics: Animals; Body Patterning; Cell Differentiation; DNA-Binding Proteins; Ectoderm; Fibroblast Growth Factor 8; Ganglia, Sensory; High Mobility Group Proteins; In Situ Hybridization; Pyrroles; Signal Transduction; SOXB1 Transcription Factors; Transcription Factors; Zebrafish | 2007 |
Acute intermittent nicotine treatment induces fibroblast growth factor-2 in the subventricular zone of the adult rat brain and enhances neuronal precursor cell proliferation.
Topics: Animals; Cell Differentiation; Cell Proliferation; Fibroblast Growth Factor 2; Hippocampus; Lateral Ventricles; Male; Nerve Regeneration; Neuronal Plasticity; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyrroles; Rats; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Nicotinic; RNA, Messenger; Stem Cells; Up-Regulation | 2007 |
Function of FGF signaling in the developmental process of the median fin fold in zebrafish.
Topics: Animal Structures; Animals; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Homeodomain Proteins; In Situ Hybridization; Microspheres; Morphogenesis; Pyrroles; Signal Transduction; Transcription Factors; Zebrafish; Zebrafish Proteins | 2007 |
Elf5 is an epithelium-specific, fibroblast growth factor-sensitive transcription factor in the embryonic lung.
Topics: Animals; Base Sequence; DNA Primers; DNA-Binding Proteins; Epithelium; Female; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Gene Expression Regulation, Developmental; Lung; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Pyrroles; Recombinant Proteins; Signal Transduction; Tissue Culture Techniques; Transcription Factors | 2007 |
Mechanism for FGF-1 to regulate biogenesis of apoE-HDL in astrocytes.
Topics: Animals; Apolipoproteins E; Astrocytes; Butadienes; Chromones; Fibroblast Growth Factor 1; Lipids; Lipoproteins, HDL; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Pyrroles; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Signal Transduction | 2007 |
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells.
Topics: Animals; Bone Morphogenetic Protein 15; Cells, Cultured; Female; Fibroblast Growth Factor 8; Glycolysis; Granulosa Cells; Growth Differentiation Factor 9; Intercellular Signaling Peptides and Proteins; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Mice; Mice, Mutant Strains; Oocytes; Phosphofructokinase-1, Type C; Protein Isoforms; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; RNA, Messenger | 2007 |
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Biological Clocks; Cleavage Stage, Ovum; Fibroblast Growth Factors; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Mice; Mice, Knockout; Models, Biological; Mutation; Pyrroles; Receptors, Notch; Signal Transduction; Somites; Triglycerides | 2007 |
FGF mediated Sulf1 regulation.
Topics: Animals; Avian Proteins; Cells, Cultured; Fibroblast Growth Factor 4; Hindlimb; Limb Buds; Mesoderm; Pyrroles; Quail; RNA, Messenger; Sulfotransferases; Toe Phalanges; Toes; Up-Regulation | 2007 |
Activation of fibroblast growth factor receptor by axotomy, through downstream p38 in dorsal root ganglion, contributes to neuropathic pain.
Topics: Animals; Axotomy; Behavior, Animal; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Male; Nerve Tissue Proteins; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; Sciatica; Time Factors | 2007 |
Fibroblast growth factor controls the timing of Scl, Lmo2, and Runx1 expression during embryonic blood development.
Topics: Animals; Biomimetic Materials; Blood Cells; Bone Morphogenetic Proteins; Cell Differentiation; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Fibroblast Growth Factors; Gastrointestinal Tract; Gene Expression Regulation, Developmental; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Metalloproteins; Proto-Oncogene Proteins; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Transcription Factors; Xenopus laevis; Xenopus Proteins | 2008 |
Evidence for a major role of endogenous fibroblast growth factor-2 in apoptotic cortex-induced subventricular zone cell proliferation.
Topics: Adult Stem Cells; Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor 2; In Vitro Techniques; Lateral Ventricles; Male; Neurons; Pyrroles; Rats; Rats, Wistar | 2007 |
Negative feedback for endothelial apoptosis: a potential physiological role for fibroblast growth factor.
Topics: Apoptosis; Cells, Cultured; Culture Media, Serum-Free; Endothelial Cells; Feedback, Physiological; Fibroblast Growth Factor 2; Humans; Protein-Tyrosine Kinases; Pyrroles; Time Factors | 2008 |
Midkine-b regulates cell specification at the neural plate border in zebrafish.
Topics: Animals; Cytokines; Gene Expression Regulation, Developmental; In Situ Hybridization; Lithium Chloride; Midkine; Neural Crest; Neurons, Afferent; p-Aminoazobenzene; Pyrroles; Retinoids; Zebrafish; Zebrafish Proteins | 2008 |
Fibroblast growth factor-derived peptides: functional agonists of the fibroblast growth factor receptor.
Topics: Amino Acid Motifs; Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Binding Sites; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Fibroblast Growth Factors; Humans; Molecular Sequence Data; Neurites; Neurons; Peptide Fragments; Protein Binding; Pyrroles; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Transfection | 2008 |
Induction of initial heart alpha-actin, smooth muscle alpha-actin, in chick pregastrula epiblast: the role of hypoblast and fibroblast growth factor-8.
Topics: Actins; Animals; Biomarkers; Chick Embryo; Fetal Proteins; Fibroblast Growth Factor 8; Gene Expression Regulation, Developmental; Germ Layers; Glycoproteins; Heart; Intercellular Signaling Peptides and Proteins; Mesoderm; Nodal Protein; Organ Culture Techniques; Protein Kinase Inhibitors; Pyrroles; Smad2 Protein; T-Box Domain Proteins; Transforming Growth Factor beta; Troponin T | 2008 |
Retina development in zebrafish requires the heparan sulfate proteoglycan agrin.
Topics: Acridine Orange; Agrin; Animals; Animals, Genetically Modified; Cell Death; ELAV Proteins; ELAV-Like Protein 3; Embryo, Nonmammalian; Enzyme Inhibitors; Fibroblast Growth Factor 3; GAP-43 Protein; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Heparan Sulfate Proteoglycans; Oligonucleotides, Antisense; Pyrroles; Retina; Sphingosine; Superior Colliculi; Transcription Factor Brn-3C; Zebrafish; Zebrafish Proteins | 2008 |
The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus.
Topics: Animals; Biomarkers; Body Patterning; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; In Situ Hybridization; Mesoderm; Organizers, Embryonic; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; T-Box Domain Proteins; Xenopus laevis; Xenopus Proteins | 2008 |
FGF signals from the nasal pit are necessary for normal facial morphogenesis.
Topics: Animals; Beak; Chick Embryo; Chickens; Ducks; Face; Fibroblast Growth Factors; Intercellular Signaling Peptides and Proteins; Morphogenesis; Pyrroles; Receptors, Fibroblast Growth Factor; Species Specificity | 2008 |
Fgf20 is required for sensory epithelial specification in the developing cochlea.
Topics: Animals; Cell Differentiation; Cochlea; Epithelial Cells; Fibroblast Growth Factors; Hair Cells, Auditory; Mice; Neurons, Afferent; Organ Culture Techniques; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction | 2008 |
Expression and regulation of HTRA1 during chick and early mouse development.
Topics: Animals; Chick Embryo; Fibroblast Growth Factor 8; Gastrulation; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; High-Temperature Requirement A Serine Peptidase 1; In Situ Hybridization; Mesoderm; Mice; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Serine Endopeptidases; Signal Transduction | 2008 |
FGF-dependent mechanosensory organ patterning in zebrafish.
Topics: Animals; Animals, Genetically Modified; Body Patterning; Cell Differentiation; Cell Polarity; Embryo, Nonmammalian; Embryonic Development; Fibroblast Growth Factor 10; Fibroblast Growth Factor 3; Gene Expression Regulation, Developmental; Lateral Line System; Mechanoreceptors; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Zebrafish; Zebrafish Proteins | 2008 |
Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart.
Topics: Animals; Cell Differentiation; Fibroblast Growth Factors; Fluorescent Antibody Technique; Heart; In Situ Hybridization; Myocytes, Cardiac; Organ Size; Pyrroles; Signal Transduction; Transcription Factors; Zebrafish | 2008 |
Mitogen-activated protein kinase-signaling stimulates Müller glia to proliferate in acutely damaged chicken retina.
Topics: Animals; Butadienes; Cell Differentiation; Cell Proliferation; Chickens; Cyclic AMP Response Element-Binding Protein; Early Growth Response Protein 1; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Nerve Regeneration; Neurogenesis; Neuroglia; Nitriles; Proto-Oncogene Proteins c-fos; Pyrroles; Receptors, Fibroblast Growth Factor; Retina; Retinal Diseases; Stem Cells | 2009 |
Enhancer detection and developmental expression of zebrafish sprouty1, a member of the fgf8 synexpression group.
Topics: Amino Acid Sequence; Animals; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; In Situ Hybridization; Molecular Sequence Data; Nervous System; Phylogeny; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Zebrafish; Zebrafish Proteins | 2008 |
Fibroblast growth factor receptor 1 is a key regulator of early adipogenic events in human preadipocytes.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adult; Aged; Becaplermin; Cell Growth Processes; Female; Fibroblast Growth Factor 1; Humans; Male; Middle Aged; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2009 |
Spatiotemporal regulation of fibroblast growth factor signal blocking for endoderm formation in Xenopus laevis.
Topics: Animals; Endoderm; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; In Situ Hybridization; Pyrroles; Receptors, Fibroblast Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Xenopus laevis; Xenopus Proteins | 2008 |
Growth factors involved in aqueous humour-induced lens cell proliferation.
Topics: Animals; Aqueous Humor; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; Fibroblast Growth Factors; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Lens, Crystalline; Platelet-Derived Growth Factor; Pyrroles; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins | 2009 |
Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways.
Topics: Animals; Cell Differentiation; Cells, Cultured; Doublecortin Domain Proteins; Doublecortin Protein; Enzyme Inhibitors; Fibroblast Growth Factors; Hedgehog Proteins; Imidazoles; Microtubule-Associated Proteins; Neurons; Neuropeptides; Prosencephalon; Pyrroles; Rats; Rats, Wistar; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Signal Transduction; Stem Cells; Tretinoin | 2009 |
An in vitro analysis of mechanical wounding-induced ligand-independent KGFR activation.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Flavonoids; Humans; Hydrogen Peroxide; Keratinocytes; Ligands; Membrane Proteins; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Reactive Oxygen Species; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction; src-Family Kinases; Wound Healing | 2009 |
FGF-activated calcium channels control neural gene expression in Xenopus.
Topics: Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carrier Proteins; Embryo, Nonmammalian; Embryonic Induction; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Pyrroles; Signal Transduction; Xenopus laevis | 2009 |
FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.
Topics: Activins; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Embryonic Stem Cells; Endoderm; Fibroblast Growth Factor 4; Gene Expression Regulation; Homeodomain Proteins; Humans; Pancreas; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Retinoic Acid; RNA, Messenger; Signal Transduction; Time Factors; Trans-Activators; Tretinoin; Up-Regulation; Wnt Proteins; Wnt3 Protein; Wnt3A Protein | 2009 |
FGF8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3F.
Topics: Age Factors; Animals; Animals, Newborn; Axons; Body Patterning; Brain; Chlorocebus aethiops; Coculture Techniques; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electroporation; Embryo, Mammalian; Enzyme Inhibitors; Fibroblast Growth Factor 8; Gene Expression Regulation, Developmental; Mesencephalon; Mice; Mice, Knockout; Neurons; Neuropilin-2; Organ Culture Techniques; Otx Transcription Factors; Pyrroles; Rats; Rats, Wistar; Semaphorins; Signal Transduction; Tyrosine 3-Monooxygenase | 2009 |
Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis.
Topics: Animals; Chick Embryo; Electroporation; Endoderm; Fibroblast Growth Factor 4; Gene Expression Regulation; Gene Expression Regulation, Developmental; In Situ Hybridization; Mesoderm; Models, Biological; Pancreas; Pyrroles; Signal Transduction; Thyroid Gland; Tretinoin | 2009 |
FGF2 is crucial for the development of bovine luteal endothelial networks in vitro.
Topics: Animals; Cattle; Cells, Cultured; Cinnamates; Endometrium; Endothelial Cells; Female; Fibroblast Growth Factor 2; Luteal Cells; Luteal Phase; Microvessels; Neovascularization, Physiologic; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyrroles; Tyrphostins; Vascular Endothelial Growth Factor A | 2009 |
Agonists of fibroblast growth factor receptor induce neurite outgrowth and survival of cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Binding Sites; Cell Survival; Cells, Cultured; Cerebellum; Fibroblast Growth Factors; Image Processing, Computer-Assisted; Immunohistochemistry; Neural Cell Adhesion Molecules; Neurogenesis; Neurons; Phytic Acid; Pyrroles; Rats; Rats, Wistar; Receptors, Fibroblast Growth Factor; Video Recording | 2009 |
Development and maturation of invariant NKT cells in the presence of lysosomal engulfment.
Topics: Animals; Cell Count; Cell Differentiation; Disease Models, Animal; Enzyme Inhibitors; Female; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Liver; Lymphocytes; Lysosomal Storage Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Mucopolysaccharidosis I; Multiple Sulfatase Deficiency Disease; Natural Killer T-Cells; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Sandhoff Disease; Spleen; Thymus Gland | 2009 |
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.
Topics: Animals; Benzamides; Blastocyst Inner Cell Mass; Cell Differentiation; Embryo Culture Techniques; Embryonic Development; Embryonic Stem Cells; Extracellular Signal-Regulated MAP Kinases; Female; Germ Layers; Leukemia Inhibitory Factor; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pluripotent Stem Cells; Pregnancy; Protein Kinase Inhibitors; Pyrroles; Rats | 2009 |
Xenopus Rnd1 and Rnd3 GTP-binding proteins are expressed under the control of segmentation clock and required for somite formation.
Topics: Animals; Cell Differentiation; Embryo, Nonmammalian; Fibroblast Growth Factors; GTP-Binding Proteins; Oligonucleotides, Antisense; Pyrroles; Receptors, Notch; rho GTP-Binding Proteins; Somites; Xenopus laevis; Xenopus Proteins | 2009 |
Comparative expression profiling reveals an essential role for raldh2 in epimorphic regeneration.
Topics: Animals; Butadienes; Cluster Analysis; Embryo, Nonmammalian; Extremities; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; In Situ Hybridization; Larva; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Oligonucleotide Array Sequence Analysis; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Regeneration; Retinal Dehydrogenase; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Wnt Proteins; Wound Healing; Zebrafish; Zebrafish Proteins | 2009 |
Basic fibroblast growth factor promotes the generation of microtubule-associated protein 2-positive cells from microglia.
Topics: Animals; Cells, Cultured; Fibroblast Growth Factor 2; Microglia; Microtubule-Associated Proteins; Pyrroles; Rats; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Up-Regulation | 2009 |
Dynamic expression of axon guidance cues required for optic tract development is controlled by fibroblast growth factor signaling.
Topics: Animals; Axons; Diencephalon; Embryo, Nonmammalian; Enzyme Inhibitors; Female; Fibroblast Growth Factors; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Mice; Nerve Tissue Proteins; Peptide Fragments; Pyrroles; Receptors, Fibroblast Growth Factor; Retinal Ganglion Cells; Semaphorin-3A; Signal Transduction; Time Factors; Visual Pathways; Xenopus | 2010 |
Reduced expression of fibroblast growth factor receptor 2IIIb in hepatocellular carcinoma induces a more aggressive growth.
Topics: Aged; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Down-Regulation; Female; Fibroblast Growth Factor 7; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Mice; Middle Aged; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2 | 2010 |
Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability.
Topics: Animals; Benzamides; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Embryo, Mammalian; Embryonic Stem Cells; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Gene Expression Profiling; Germ Cells; Glycogen Synthase Kinase 3; Immunohistochemistry; Karyotyping; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyridines; Pyrimidines; Pyrroles; Receptors, Fibroblast Growth Factor; Recombination, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Focal adhesion kinase is essential for cardiac looping and multichamber heart formation.
Topics: Animals; Blotting, Western; Caspase 3; Cell Proliferation; Cells, Cultured; Embryo, Nonmammalian; Fibroblast Growth Factor 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Heart; Immunohistochemistry; In Situ Hybridization; Microinjections; Microscopy, Confocal; Morphogenesis; Myocardium; Myocytes, Cardiac; Oligonucleotides, Antisense; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Tropomyosin; Xenopus laevis | 2010 |
Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.
Topics: Animal Structures; Animals; Antigens, CD; beta Catenin; Bone Marrow Cells; Butadienes; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Colony-Forming Units Assay; Erythropoiesis; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factors; GATA1 Transcription Factor; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Lymphopoiesis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myelopoiesis; Nitriles; Oxidoreductases Acting on Sulfur Group Donors; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Notch1; Signal Transduction; Stem Cells; Sulfatases; Sulfotransferases; Wnt Proteins | 2010 |
Highlighted article: "Focal adhesion kinase is essential for cardiac looping and multi-chamber heart formation" by Doherty, Conlon, Mack, and Taylor.
Topics: Animals; Cell Proliferation; Cells, Cultured; Embryo, Nonmammalian; Fibroblast Growth Factor 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Heart; Microinjections; Morphogenesis; Myocardium; Myocytes, Cardiac; Oligonucleotides, Antisense; Pyrroles; Xenopus laevis | 2010 |
Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1.
Topics: Angiogenesis Inducing Agents; Cells, Cultured; Endothelial Cells; Enzyme Activation; Ginsenosides; Hormone Antagonists; Humans; Mifepristone; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Receptor Cross-Talk; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Glucocorticoid; RNA Interference | 2011 |
Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.
Topics: Animals; Animals, Newborn; Cerebral Ventriculitis; Chemotaxis; CHO Cells; Cricetinae; Cricetulus; Culture Media, Conditioned; Cysteine; Enzyme Inhibitors; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Humans; Immunoprecipitation; Laminin; Mutation; Nerve Tissue Proteins; Neural Stem Cells; Protein Structure, Tertiary; Pyrroles; Rats; Receptor, Fibroblast Growth Factor, Type 1; Transfection | 2010 |
Wnt/β-catenin dependent cell proliferation underlies segmented lateral line morphogenesis.
Topics: Animals; Aphidicolin; beta Catenin; Bromodeoxyuridine; Cell Proliferation; DNA Primers; Embryo, Nonmammalian; Fibroblast Growth Factors; Gene Knockout Techniques; Hydroxyurea; In Situ Hybridization; In Situ Nick-End Labeling; Lateral Line System; Morphogenesis; Pyrroles; Signal Transduction; Time-Lapse Imaging; Transcription Factors; Wnt Proteins; Zebrafish | 2011 |
A novel glycosylation signal regulates transforming growth factor beta receptors as evidenced by endo-beta-galactosidase C expression in rodent cells.
Topics: Animals; Benzamides; Cell Proliferation; Dioxoles; Disaccharides; Glycoside Hydrolases; Glycosylation; Immunoprecipitation; Mice; Models, Molecular; NIH 3T3 Cells; Phosphorylation; Protein Processing, Post-Translational; Pyrroles; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Signal Transduction; Smad2 Protein | 2011 |
Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.
Topics: Animals; Apoptosis; Benzimidazoles; Blotting, Western; Carcinoma, Transitional Cell; Cell Cycle; Cell Proliferation; Cells, Cultured; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Quinolones; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 3; Urinary Bladder Neoplasms; Urothelium; Xenograft Model Antitumor Assays | 2011 |
Fibroblast growth factor requirements for in vitro development of bovine embryos.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Embryonic Development; Fertilization in Vitro; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hot Temperature; Interferon Type I; Pregnancy Proteins; Protein-Tyrosine Kinases; Pyrroles; Receptors, Fibroblast Growth Factor; RNA, Messenger | 2011 |
Isolation and characterization of node/notochord-like cells from mouse embryonic stem cells.
Topics: Animals; Antigens, Differentiation; Benzamides; Cell Differentiation; Cell Line; Cell Proliferation; Chick Embryo; Dioxoles; Embryonic Stem Cells; Green Fluorescent Proteins; Hepatocyte Nuclear Factor 3-beta; Homeodomain Proteins; Intercellular Signaling Peptides and Proteins; Mice; Notochord; Organizers, Embryonic; Peptide Hormones; Pyrroles; Receptors, Growth Factor; Recombinant Fusion Proteins; Signal Transduction; Tissue Culture Techniques; Transplantation, Heterologous | 2011 |
Polysialylation promotes neural cell adhesion molecule-mediated cell migration in a fibroblast growth factor receptor-dependent manner, but independent of adhesion capability.
Topics: Animals; Cell Adhesion; Cell Movement; Mice; Neural Cell Adhesion Molecules; NIH 3T3 Cells; Pyrroles; Receptors, Fibroblast Growth Factor; Sialic Acids; Structure-Activity Relationship | 2011 |
FGF8 signaling is chemotactic for cardiac neural crest cells.
Topics: Animals; Apoptosis; Butadienes; Cell Movement; Cell Proliferation; Chemotaxis; Chick Embryo; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 8; Green Fluorescent Proteins; Heart; Immunohistochemistry; In Situ Hybridization; Mesoderm; Mitogen-Activated Protein Kinases; Myocardium; Neural Crest; Nitriles; Pharynx; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction | 2011 |
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish.
Topics: Animals; Animals, Genetically Modified; Embryo, Nonmammalian; ErbB Receptors; Gene Expression Regulation, Developmental; Heart; Homeobox Protein Nkx-2.5; In Situ Hybridization; Mice; Muscle Proteins; Myocardium; Pyrroles; Signal Transduction; Stem Cells; Time Factors; Transcription Factors; Zebrafish; Zebrafish Proteins | 2011 |
Nodal signal is required for morphogenetic movements of epiblast layer in the pre-streak chick blastoderm.
Topics: Animals; Blastoderm; Cell Movement; Chick Embryo; Chickens; Epithelium; Fetal Proteins; Left-Right Determination Factors; Morphogenesis; Nodal Protein; Pyrroles; Signal Transduction; T-Box Domain Proteins | 2011 |
Involvement of NCAM and FGF receptor signaling in the development of analgesic tolerance to morphine.
Topics: Analgesics; Animals; Base Sequence; Chronic Pain; Drug Tolerance; Enzyme Activation; Gene Expression Regulation, Enzymologic; Male; Mice; Morphine; Neural Cell Adhesion Molecules; Oligonucleotides, Antisense; Protein Kinase C-alpha; Protein Kinase Inhibitors; Pyrroles; Receptors, Fibroblast Growth Factor; Receptors, Opioid, kappa; Signal Transduction; Time Factors | 2011 |
Inhibition of fibroblast growth factor receptor 1: influence on tympanic membrane wound healing in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Male; Protein-Tyrosine Kinases; Pyrroles; Rats; Rats, Inbred Lew; Receptor, Fibroblast Growth Factor, Type 1; Tympanic Membrane; Tympanic Membrane Perforation; Wound Healing | 2012 |
Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivision.
Topics: Animals; Body Patterning; Chick Embryo; Diffusion; Extremities; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Homeodomain Proteins; Limb Buds; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Pyrroles; Signal Transduction; Somites; Tretinoin; Wings, Animal | 2011 |
Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle.
Topics: Animals; Animals, Genetically Modified; Body Patterning; Ear; Ear, Inner; Embryo, Nonmammalian; Embryonic Induction; Enzyme Inhibitors; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hedgehog Proteins; Pyrroles; Signal Transduction; Zebrafish; Zebrafish Proteins | 2011 |
Zebrafish Ext2 is necessary for Fgf and Wnt signaling, but not for Hh signaling.
Topics: Animals; Cell Differentiation; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Hedgehog Proteins; Heparitin Sulfate; Morpholinos; N-Acetylglucosaminyltransferases; Pyrroles; Receptors, Fibroblast Growth Factor; Receptors, Wnt; Retina; Tail; Veratrum Alkaloids; Wnt Signaling Pathway; Zebrafish; Zebrafish Proteins | 2011 |
Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway.
Topics: Butadienes; Cell Differentiation; Cells, Cultured; Culture Media; Embryonic Stem Cells; Enzyme Activation; Eye Proteins; Fibroblast Growth Factors; Gene Expression Regulation; Homeodomain Proteins; Humans; MAP Kinase Signaling System; Neural Plate; Nitriles; Paired Box Transcription Factors; PAX6 Transcription Factor; Phenanthrenes; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pyrroles; Repressor Proteins | 2011 |
Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis.
Topics: Animals; Cattle; Cells, Cultured; Cinnamates; Corpus Luteum; Endothelial Cells; Female; Fibroblast Growth Factor 2; Luteal Cells; Neovascularization, Physiologic; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
FGF-2 and Anosmin-1 are selectively expressed in different types of multiple sclerosis lesions.
Topics: Adult; Adult Stem Cells; Aged; Aged, 80 and over; Animals; Antigens; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cerebral Cortex; Cricetinae; Cricetulus; Enzyme Inhibitors; Extracellular Matrix Proteins; Female; Fibroblast Growth Factor 2; Gangliosides; Glial Fibrillary Acidic Protein; HLA-DR Antigens; Humans; Male; Membrane Proteins; Mice; Middle Aged; Multiple Sclerosis; Nerve Tissue Proteins; Oligodendroglia; Phosphoproteins; Postmortem Changes; Proteoglycans; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor alpha; Transfection; Up-Regulation; Zonula Occludens-1 Protein | 2011 |
Optimization of culture conditions to support long-term self-renewal of buffalo (Bubalus bubalis) embryonic stem cell-like cells.
Topics: Animals; Antigens, Differentiation; Buffaloes; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Embryonic Stem Cells; Feeder Cells; Female; Protein Kinase Inhibitors; Pyrroles; Signal Transduction | 2011 |
Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2.
Topics: Angiogenesis Inducing Agents; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblast Growth Factor 2; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Receptors, Fibroblast Growth Factor | 2012 |
FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction.
Topics: Animals; Bone Morphogenetic Proteins; Chick Embryo; Ectoderm; Electroporation; Fibroblast Growth Factors; Fluorescent Antibody Technique; Gastrula; Germ Layers; Image Processing, Computer-Assisted; In Situ Hybridization; Mesoderm; Microscopy; Mitogen-Activated Protein Kinases; Models, Biological; Neural Crest; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Smad Proteins | 2012 |
Fibroblast growth factor 2 inhibits the expression of stromal cell-derived factor 1α in periodontal ligament cells derived from human permanent teeth in vitro.
Topics: Cells, Cultured; Chemokine CXCL12; Fibroblast Growth Factor 2; Humans; Periodontal Ligament; Pyrroles; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 1; Regeneration; RNA, Messenger; Stem Cells; Tooth | 2012 |
Disruption of fibroblast growth factor receptor signaling in bovine cumulus-oocyte complexes during in vitro maturation reduces subsequent embryonic development.
Topics: Animals; Cattle; Cumulus Cells; Embryonic Development; Female; Fertilization in Vitro; Oocytes; Pregnancy; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; Receptors, Fibroblast Growth Factor; RNA; Signal Transduction | 2012 |
Endogenously produced FGF2 is essential for the survival and proliferation of cultured mouse spermatogonial stem cells.
Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Feeder Cells; Fibroblast Growth Factor 2; Gene Expression Regulation; Gene Knockdown Techniques; Male; MAP Kinase Signaling System; Mice; Protein Isoforms; Pyrroles; Spermatogenesis; Spermatogonia; Stem Cells | 2012 |
Neural crest cells pattern the surface cephalic ectoderm during FEZ formation.
Topics: Animals; Chick Embryo; Ectoderm; Face; Fibroblast Growth Factors; Hedgehog Proteins; Mesoderm; Neural Crest; Protein-Tyrosine Kinases; Pyrroles; Quail; Signal Transduction | 2012 |
Differential effects of TGF-β1 and FGF-2 on SDF-1α expression in human periodontal ligament cells derived from deciduous teeth in vitro.
Topics: Bone Marrow Cells; Cell Line; Cell Movement; Chemokine CXCL12; Fibroblast Growth Factor 2; Humans; Mesenchymal Stem Cells; Periodontal Ligament; Phosphorylation; Pyrroles; Receptors, Fibroblast Growth Factor; RNA Interference; RNA, Messenger; RNA, Small Interfering; Smad2 Protein; Smad3 Protein; Smad7 Protein; Tooth, Deciduous; Transforming Growth Factor beta1 | 2012 |
Antidepressant effects of fibroblast growth factor-2 in behavioral and cellular models of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Bromodeoxyuridine; Depressive Disorder; Disease Models, Animal; Fibroblast Growth Factor 2; Fluoxetine; Imipramine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroglia; Prefrontal Cortex; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; Stress, Psychological | 2012 |
Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla.
Topics: Animals; Cell Proliferation; Cell Transdifferentiation; Chick Embryo; Fibroblast Growth Factors; Hair Cells, Auditory; Labyrinth Supporting Cells; Organ Culture Techniques; Organ of Corti; Phenotype; Protein Kinase Inhibitors; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; SOXB1 Transcription Factors | 2012 |
Fgf-dependent glial cell bridges facilitate spinal cord regeneration in zebrafish.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cell Proliferation; Dextrans; Disease Models, Animal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fibroblast Growth Factor 3; Fibroblast Growth Factor 8; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; Intermediate Filament Proteins; Ki-67 Antigen; Mitogen-Activated Protein Kinase Kinases; Motor Activity; Nerve Regeneration; Nerve Tissue Proteins; Nestin; Neuroglia; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Recovery of Function; Rhodamines; RNA, Messenger; Signal Transduction; Spinal Cord Injuries; Time Factors; Zebrafish; Zebrafish Proteins | 2012 |
Use of kinase inhibitors to correct ΔF508-CFTR function.
Topics: Animals; Benzazepines; Cell Line; Cricetinae; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Indoles; Ion Transport; Membrane Proteins; Oxindoles; Propionates; Protein Kinase Inhibitors; Protein Transport; Protein-Tyrosine Kinases; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA Interference; RNA, Small Interfering; Sequence Deletion; Signal Transduction; Zearalenone | 2012 |
FGF inhibition directs BMP4-mediated differentiation of human embryonic stem cells to syncytiotrophoblast.
Topics: Activins; Animals; Autocrine Communication; Benzamides; Bone Morphogenetic Protein 4; CDX2 Transcription Factor; Cell Differentiation; Cell Fusion; Cell Line; Chorionic Gonadotropin, beta Subunit, Human; Dioxoles; Embryonic Stem Cells; Endoderm; Female; Fibroblast Growth Factors; Gene Expression Regulation; Homeodomain Proteins; Humans; Mesoderm; Mice; Models, Biological; Nodal Protein; Placenta; Pregnancy; Pyrroles; Signal Transduction; Trophoblasts; Wnt Proteins | 2012 |
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.
Topics: Acetanilides; Caffeic Acids; Cell Culture Techniques; Cell Differentiation; Cell Line; Gene Expression Regulation, Developmental; Humans; Molecular Sequence Data; NAV1.8 Voltage-Gated Sodium Channel; Nociceptors; Pain; Pluripotent Stem Cells; Pyridines; Pyrimidines; Pyrroles; Signal Transduction; Small Molecule Libraries; Tetrodotoxin | 2012 |
Nuclear fibroblast growth factor 2 (FGF2) isoforms inhibit bone marrow stromal cell mineralization through FGF23/FGFR/MAPK in vitro.
Topics: Animals; Calcification, Physiologic; Cell Nucleus; Culture Media, Conditioned; Fibroblast Growth Factor 2; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Flavonoids; Gene Expression Regulation; Genetic Vectors; Humans; Male; Mesenchymal Stem Cells; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Weight; Neutralization Tests; Osteocalcin; Osteogenesis; Phosphorylation; Protein Isoforms; Pyrroles; Receptors, Fibroblast Growth Factor; RNA, Messenger; Time Factors | 2013 |
Fibroblast growth factor-2: an endogenous antidepressant and anxiolytic molecule?
Topics: Animals; Antidepressive Agents; Fibroblast Growth Factor 2; Male; Neuroglia; Prefrontal Cortex; Pyrroles; Receptors, Fibroblast Growth Factor; Stress, Psychological | 2012 |
Eosinophil cationic protein enhances cardiomyocyte differentiation of P19CL6 embryonal carcinoma cells by stimulating the FGF receptor signaling pathway.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; Embryonal Carcinoma Stem Cells; Eosinophil Cationic Protein; Extracellular Signal-Regulated MAP Kinases; Fetal Proteins; GATA4 Transcription Factor; Mice; Myocytes, Cardiac; Myosin Heavy Chains; Phosphorylation; Protein-Tyrosine Kinases; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; T-Box Domain Proteins | 2012 |
ATP oscillations mediate inductive action of FGF and Shh signalling on prechondrogenic condensation.
Topics: Adenosine Triphosphate; Animals; Cell Line; Chondrocytes; Chondrogenesis; Cinnamates; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Genes, Reporter; Hedgehog Proteins; Insulin; Luminescent Measurements; Mice; Pyrroles; Signal Transduction; Transfection; Veratrum Alkaloids | 2013 |
Cryopreservation and long-term maintenance of bovine embryo-derived cell lines.
Topics: Animals; Benzamides; Cattle; Cell Culture Techniques; Cell Differentiation; Cryopreservation; DNA Primers; Embryo, Mammalian; Embryonic Stem Cells; Fluorescent Antibody Technique; Karyotyping; Pyridines; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; Vitrification | 2013 |
RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Biphenyl Compounds; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Enzyme Activation; Fibroblast Growth Factor 2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Nitrophenols; Oligonucleotide Array Sequence Analysis; Piperazines; Protein Kinase C-delta; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sulfonamides | 2013 |
Autocrine fibroblast growth factor 2-mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tension.
Topics: Adipogenesis; Cell Differentiation; Cell Hypoxia; Cell Proliferation; Cell Survival; Enzyme Activation; Extracellular Matrix; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Humans; Mesenchymal Stem Cells; Osteogenesis; Pyrroles; Reactive Oxygen Species; tert-Butylhydroperoxide | 2013 |
Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway.
Topics: Adaptor Proteins, Signal Transducing; Bone Regeneration; Cell Differentiation; Cell Line, Tumor; Coculture Techniques; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Humans; MAP Kinase Signaling System; Membrane Proteins; Osteoblasts; Osteocytes; Phosphorylation; Polyphosphates; Protein-Tyrosine Kinases; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction | 2012 |
Fibroblast growth factor 2 induces the precocious development of endothelial cell networks in bovine luteinising follicular cells.
Topics: Analysis of Variance; Animals; Cattle; Cell Culture Techniques; Cinnamates; Corpus Luteum; Endothelial Cells; Female; Fibroblast Growth Factor 2; Image Processing, Computer-Assisted; Luteinizing Hormone; Microscopy; Neovascularization, Physiologic; Progesterone; Pyrroles; Receptors, Vascular Endothelial Growth Factor | 2013 |
Fibroblast growth factor receptor 2c signaling is required for intestinal cell differentiation in zebrafish.
Topics: Animals; Animals, Genetically Modified; Bromodeoxyuridine; Cell Differentiation; DNA Primers; Enteroendocrine Cells; Fluorescent Antibody Technique; Goblet Cells; In Situ Hybridization; In Situ Nick-End Labeling; Intestines; Microinjections; Morpholinos; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Zebrafish | 2013 |
Anteroposterior and dorsoventral patterning are coordinated by an identical patterning clock.
Topics: Animals; Binding Sites; Biological Clocks; Blotting, Western; Body Patterning; Bone Morphogenetic Proteins; Embryo, Nonmammalian; Fibroblast Growth Factors; Gastrulation; Gene Expression Regulation, Developmental; Glycogen Synthase Kinase 3; Humans; Models, Animal; Morpholinos; Phosphorylation; Proteolysis; Pyrroles; RNA, Messenger; Smad1 Protein; Smad5 Protein; Transgenes; Tretinoin; Wnt Signaling Pathway; Zebrafish; Zebrafish Proteins | 2013 |
Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.
Topics: Activins; Cell Differentiation; Cell Line; Cell Lineage; Cell Proliferation; Cells, Cultured; Gene Expression Regulation; Humans; Niacinamide; Pluripotent Stem Cells; Pyrroles; Retinal Pigment Epithelium; RNA, Messenger; Time Factors; Vasoactive Intestinal Peptide; Visual Fields | 2013 |
Fibroblast growth factor-2 up-regulates the expression of nestin through the Ras-Raf-ERK-Sp1 signaling axis in C6 glioma cells.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Glioma; Intermediate Filament Proteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Tissue Proteins; Nestin; Pyrroles; raf Kinases; ras Proteins; Rats; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 3; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sp1 Transcription Factor; Up-Regulation | 2013 |
Dimerized glycosaminoglycan chains increase FGF signaling during zebrafish development.
Topics: Animals; Animals, Genetically Modified; Base Sequence; Dimerization; Embryo, Nonmammalian; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Glycosaminoglycans; Glycosides; In Situ Hybridization; Molecular Sequence Data; Protein Kinase Inhibitors; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Syndecan-1; Zebrafish; Zebrafish Proteins | 2013 |
Roles for FGF in lamprey pharyngeal pouch formation and skeletogenesis highlight ancestral functions in the vertebrate head.
Topics: Animals; Biological Evolution; Bone and Bones; Cartilage; Embryo, Nonmammalian; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Head; Lampreys; Larva; Models, Biological; Neural Crest; Osteogenesis; Pharynx; Pyrroles; Receptors, Fibroblast Growth Factor; Sequence Homology, Amino Acid; Signal Transduction; Tretinoin; Xenopus laevis | 2014 |
FGFR-ERK signaling is an essential component of tissue separation.
Topics: Animals; Animals, Genetically Modified; Blotting, Western; Butadienes; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hydra; In Situ Hybridization; Microscopy, Confocal; Microscopy, Fluorescence; Morphogenesis; Nitriles; Phosphorylation; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; Time Factors | 2014 |
Retinoic acid regulates Lhx8 expression via FGF-8b to the upper jaw development of chick embryo.
Topics: Acyclic Monoterpenes; Animals; Cell Differentiation; Chick Embryo; Down-Regulation; Fibroblast Growth Factor 8; Homeodomain Proteins; Jaw; LIM-Homeodomain Proteins; Mesoderm; Monoterpenes; Morphogenesis; MSX1 Transcription Factor; Pyrroles; Signal Transduction; Transcription Factors; Tretinoin | 2015 |
KGFR as a possible therapeutic target in middle ear cholesteatoma.
Topics: Animals; Benzamides; Cholesteatoma, Middle Ear; Diphenylamine; Drug Evaluation, Preclinical; Ear Canal; Extracellular Signal-Regulated MAP Kinases; Genetic Vectors; Male; Pyrroles; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 2; Transfection | 2014 |
Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Cells, Cultured; Drug Evaluation, Preclinical; Endothelial Cells; Fibroblast Growth Factor 2; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Indoles; Microscopy, Video; Neovascularization, Physiologic; Pyrroles; Recombinant Proteins; Spheroids, Cellular; Vascular Endothelial Growth Factor A | 2015 |
Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling.
Topics: Actins; Animals; Bone Morphogenetic Proteins; Cell Shape; Cells, Cultured; Chick Embryo; Chondrocytes; Chondrogenesis; Cytochalasin D; Cytoskeleton; Fibroblast Growth Factors; Heterocyclic Compounds, 4 or More Rings; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; Transforming Growth Factor beta | 2015 |
Specific induction of cranial placode cells from Xenopus ectoderm by modulating the levels of BMP, Wnt, and FGF signaling.
Topics: Animals; Body Patterning; Bone Morphogenetic Proteins; Ectoderm; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Glycoproteins; Head; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Microinjections; Neural Crest; Neural Plate; Plasmids; Pyrazoles; Pyrimidines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skull; Wnt Proteins; Xenopus laevis; Xenopus Proteins | 2015 |
Enhanced Dentinogenesis of Pulp Progenitors by Early Exposure to FGF2.
Topics: Animals; Butadienes; Cell Cycle; Dental Pulp; Dentinogenesis; Fibroblast Growth Factor 2; Mice; Mice, Transgenic; Nitriles; Pyrroles; Signal Transduction; Stem Cells | 2015 |
Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.
Topics: Achondroplasia; Animals; Benzamides; Cartilage; Catalysis; Cells, Cultured; Chick Embryo; Chondrocytes; Humans; Mice; Phenylurea Compounds; Piperazines; Pyrazoles; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Signal Transduction; Syndrome | 2016 |
FAIMS and Phosphoproteomics of Fibroblast Growth Factor Signaling: Enhanced Identification of Multiply Phosphorylated Peptides.
Topics: Amino Acid Sequence; Chromatography, Liquid; Dasatinib; Fibroblast Growth Factors; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteomics; Pyrroles; Receptors, Fibroblast Growth Factor; Signal Transduction; src-Family Kinases; Tandem Mass Spectrometry | 2015 |
Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Hydrogen-Ion Concentration; Infarction, Middle Cerebral Artery; Male; Mice, 129 Strain; Mice, Inbred C57BL; Pericytes; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Receptors, Fibroblast Growth Factor; Stroke; Up-Regulation | 2016 |
Inhibition of FGF signaling accelerates neural crest cell differentiation of human pluripotent stem cells.
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Fibroblast Growth Factors; Humans; Neural Crest; Pluripotent Stem Cells; Pyrroles; Signal Transduction | 2016 |
FGF Signaling Prevents the Terminal Differentiation of Odontoblasts.
Topics: Animals; Bone Morphogenetic Proteins; Butadienes; Carrier Proteins; Cell Differentiation; Cells, Cultured; Dental Pulp; Dentinogenesis; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Immunohistochemistry; Mice; Nitriles; Odontoblasts; Phosphoproteins; Pyrroles; Real-Time Polymerase Chain Reaction; Sialoglycoproteins; Signal Transduction | 2017 |
Nervous system disruption and swimming abnormality in early-hatched pufferfish (Takifugu niphobles) larvae caused by pyrene is independent of aryl hydrocarbon receptors.
Topics: Animals; beta-Naphthoflavone; Central Nervous System; Fibroblast Growth Factors; Heart Rate; Nervous System; Petroleum Pollution; Polycyclic Aromatic Hydrocarbons; Pyrenes; Pyrroles; Receptors, Aryl Hydrocarbon; Swimming; Takifugu | 2017 |
Differential effects of amnion and chorion membrane extracts on osteoblast-like cells due to the different growth factor composition of the extracts.
Topics: Amnion; Benzodioxoles; Cell Line; Cell Proliferation; Cell Shape; Chorion; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Osteoblasts; Osteogenesis; Pyridines; Pyrroles; Tissue Extracts | 2017 |
Effects of insulin like growth factors on early embryonic chick limb myogenesis.
Topics: Animals; Butadienes; Chick Embryo; Chromones; Enzyme Inhibitors; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Hindlimb; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Morpholines; Muscle Development; Muscle, Skeletal; MyoD Protein; Myogenin; Nitriles; PAX3 Transcription Factor; Phosphoinositide-3 Kinase Inhibitors; Podophyllotoxin; Pyrroles; Receptor, IGF Type 1; Receptors, Vascular Endothelial Growth Factor | 2017 |
Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish.
Topics: Animals; Animals, Genetically Modified; Clustered Regularly Interspaced Short Palindromic Repeats; Embryo, Nonmammalian; Enzyme Inhibitors; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Homeodomain Proteins; Intercellular Signaling Peptides and Proteins; Morphogenesis; Mutation; Nerve Tissue Proteins; Oligodendrocyte Transcription Factor 2; Pyrroles; Rhombencephalon; RNA, Messenger; Zebrafish; Zebrafish Proteins | 2018 |
Cardiac Fgf-16 Expression Supports Cardiomyocyte Survival and Increases Resistance to Doxorubicin Cytotoxicity.
Topics: Adenoviridae; Animals; Animals, Newborn; Apoptosis; Atrial Natriuretic Factor; Biological Transport; Cardiomyopathies; Cell Survival; Cytotoxins; Doxorubicin; Echocardiography; Fibroblast Growth Factors; Gene Expression Regulation; Genetic Vectors; Heart Function Tests; Injections, Intraperitoneal; Myocardium; Myocytes, Cardiac; Primary Cell Culture; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; RNA, Small Interfering; Signal Transduction | 2018 |
Extracellular matrix protein anosmin-1 modulates olfactory ensheathing cell maturation in chick olfactory bulb development.
Topics: Animals; Cell Proliferation; Chick Embryo; Fatty Acid-Binding Protein 7; Fibroblast Growth Factor 2; Nerve Tissue Proteins; Neuroglia; Olfactory Bulb; Pyrroles; RNA, Small Interfering | 2019 |
FGF-2 signaling activation in the hippocampus contributes to the behavioral and cellular responses to puerarin.
Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Fibroblast Growth Factor 2; Food Preferences; Hippocampus; Isoflavones; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Stress, Psychological | 2019 |
VEGF and FGF signaling during head regeneration in hydra.
Topics: Animals; Computer Simulation; Fibroblast Growth Factor 1; Fibroblast Growth Factors; Gene Expression Regulation; Head; Humans; Hydra; Indoles; Protein Domains; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Regeneration; Signal Transduction; Structural Homology, Protein; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes.
Topics: Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Survival; Female; Fibroblast Growth Factor 9; Gene Expression Regulation, Developmental; Germ Cells; Humans; Leydig Cells; Male; Ovary; Pregnancy; Pregnancy Trimester, First; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Sertoli Cells; Signal Transduction; Testis; Wnt4 Protein | 2019 |
Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1.
Topics: Actins; Animals; Cells, Cultured; Disease Models, Animal; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibrosis; Heart Diseases; Male; Myocytes, Cardiac; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 1; Transforming Growth Factor beta1; Up-Regulation | 2020 |
Topics: Animals; Cell Differentiation; Cell Movement; Embryo, Nonmammalian; Endoderm; Female; Fibroblast Growth Factors; Gastrulation; Gene Expression Regulation, Developmental; Mesoderm; Microinjections; Pyrroles; Receptors, Notch; Transcription Factors; Xenopus; Xenopus Proteins | 2020 |
FGF signaling acts on different levels of mesoderm development within Spiralia.
Topics: Animals; Body Patterning; Fibroblast Growth Factors; Gastrulation; Mesoderm; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Transcription Factors; Urochordata | 2021 |
FGF signalling plays similar roles in development and regeneration of the skeleton in the brittle star Amphiura filiformis.
Topics: Animals; Bone and Bones; Bone Development; Bone Regeneration; Ectoderm; Embryonic Development; Extremities; Fibroblast Growth Factors; Mesoderm; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Starfish; Vascular Endothelial Growth Factor A | 2021 |