pyrroles has been researched along with s 8932 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 16 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez, JC; Annane, D; Etting, I; Larabi, IA; Moine, P | 1 |
| Bunel, V; Descamps, D; Jaquet, P; Le Hingrat, Q; Lê, MP; Mal, H; Massias, L; Messika, J; Peytavin, G; Timsit, JF; Visseaux, B; Wicky, PH | 1 |
| Bunel, V; Descamps, D; Jaquet, P; Le Beller, C; Le Hingrat, Q; Lê, MP; Mal, H; Massias, L; Messika, J; Peytavin, G; Timsit, JF; Visseaux, B; Wicky, PH | 1 |
| Muller, FL; Yan, VC | 1 |
| Cies, JJ; Davis, MR; Pham, CU | 1 |
| Arnold, L; Chernobrovkin, A; Friman, T; Martinez Molina, D | 1 |
| Chen, YS; Chu, J; German, P; Humeniuk, R; John Ling, KH; Mathias, A; Tarnowski, T; van Ingen, E; Xiao, D | 1 |
| Brügel, M; Habler, K; Liebchen, U; Paal, M; Scharf, C; Schönermarck, U; Teupser, D; Vogeser, M | 1 |
| Bojkova, D; Buyck, C; Ciesek, S; Cinatl, J; De Jonghe, S; De Meyer, S; Jochmans, D; Leyssen, P; Neyts, J; Van Damme, E; Van Loock, M | 1 |
| Babusis, D; Cao, H; German, P; Humeniuk, R; Kirby, BJ; Ling, J; Lutz, JD; Mathias, A; Osinusi, A; Porter, D; Reddy, YS; Wei, X | 1 |
| Gandhi, M; Gerona, R; Metcalfe, J; Ong, CM; Reckers, A; Wu, AHB | 1 |
| Abe, T; Maekawa, M; Mano, N; Sato, T; Yamaguchi, H | 1 |
| Deb, S; Reeves, AA | 1 |
| Fenyvesi, É; Hirka, G; Puskás, I; Renkecz, T; Sirok, D; Sohajda, T; Stáhl, J; Szente, L | 1 |
| Agrati, C; Ascoli Bartoli, T; Benvenuto, D; Marchioni, L; Nicastri, E; Stazi, GV; Tempestilli, M | 1 |
| Castillo, D; Cosaro, E; Murphy, BG; Pires, J; Reagan, KL | 1 |
1 review(s) available for pyrroles and s 8932
| Article | Year |
|---|---|
Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor.
Topics: Adenosine; Adenosine Monophosphate; Adult; Alanine; Animals; Antiviral Agents; Area Under Curve; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Interactions; Furans; Half-Life; Humans; Metabolic Clearance Rate; Pyrroles; SARS-CoV-2; Triazines | 2021 |
1 trial(s) available for pyrroles and s 8932
| Article | Year |
|---|---|
Efficacy of Oral Remdesivir Compared to GS-441524 for Treatment of Cats with Naturally Occurring Effusive Feline Infectious Peritonitis: A Blinded, Non-Inferiority Study.
Topics: Adenosine; Animals; Antiviral Agents; Cats; Double-Blind Method; Equivalence Trials as Topic; Feline Infectious Peritonitis; Furans; Pyrroles; Triazines | 2023 |
14 other study(ies) available for pyrroles and s 8932
| Article | Year |
|---|---|
Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; Betacoronavirus; Chromatography, Liquid; Coronavirus Infections; COVID-19; Drug Monitoring; Drug Stability; Female; Furans; Humans; Limit of Detection; Male; Middle Aged; Pandemics; Pneumonia, Viral; Pyrroles; Reproducibility of Results; SARS-CoV-2; Tandem Mass Spectrometry; Triazines | 2020 |
Removal of Remdesivir's Metabolite GS-441524 by Hemodialysis in a Double Lung Transplant Recipient with COVID-19.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; beta-Cyclodextrins; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Interactions; Furans; Humans; Intensive Care Units; Lung Transplantation; Multiple Organ Failure; Pandemics; Pneumonia, Viral; Pyrroles; Renal Dialysis; SARS-CoV-2; Transplant Recipients; Triazines | 2020 |
Reply to Yan and Muller, "Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir's Nephrotoxicity".
Topics: Adenosine; Adenosine Monophosphate; Alanine; beta-Cyclodextrins; COVID-19; Furans; Humans; Lung Transplantation; Neuroglia; Pandemics; Pyrroles; Renal Dialysis; SARS-CoV-2; Transplant Recipients; Triazines | 2020 |
Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir's Nephrotoxicity.
Topics: Adenosine; Adenosine Monophosphate; Alanine; beta-Cyclodextrins; COVID-19; Furans; Humans; Lung; Pandemics; Pyrroles; Renal Dialysis; SARS-CoV-2; Transplant Recipients; Triazines | 2020 |
Remdesivir and GS-441524 plasma concentrations in patients with end-stage renal disease on haemodialysis.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Furans; Humans; Kidney Failure, Chronic; Pyrroles; Renal Dialysis; Triazines | 2021 |
CETSA MS Profiling for a Comparative Assessment of FDA-Approved Antivirals Repurposed for COVID-19 Therapy Identifies TRIP13 as a Remdesivir Off-Target.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; ATPases Associated with Diverse Cellular Activities; Cell Cycle Proteins; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; Furans; Hep G2 Cells; Humans; Mass Spectrometry; Proteomics; Pyrroles; Triazines; United States; United States Food and Drug Administration | 2021 |
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; Chromatography, High Pressure Liquid; COVID-19 Drug Treatment; Drug Monitoring; Furans; Humans; Limit of Detection; Pyrroles; Tandem Mass Spectrometry; Triazines | 2021 |
Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum
Topics: Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Azithromycin; Chloroquine; Chromatography, Liquid; COVID-19; COVID-19 Drug Treatment; Furans; Humans; Hydroxychloroquine; Isotopes; Lopinavir; Pandemics; Pyrazines; Pyrroles; Ritonavir; SARS-CoV-2; Tandem Mass Spectrometry; Triazines | 2021 |
In vitro activity of itraconazole against SARS-CoV-2.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Caco-2 Cells; Cell Line, Tumor; Chlorocebus aethiops; COVID-19 Drug Treatment; Drug Repositioning; Furans; Humans; Itraconazole; Pyrroles; SARS-CoV-2; Triazines; Vero Cells; Virus Replication | 2021 |
A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; Chromatography, Liquid; COVID-19 Drug Treatment; Dexamethasone; Furans; Humans; Pyrroles; SARS-CoV-2; Tandem Mass Spectrometry; Triazines | 2021 |
Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-19.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Animals; Antiviral Agents; Cell Line; COVID-19; COVID-19 Drug Treatment; Dogs; Dose-Response Relationship, Drug; Drug Approval; Furans; Humans; Kidney; Kidney Tubules, Proximal; Madin Darby Canine Kidney Cells; Organic Anion Transporters; Pyrroles; Triazines | 2021 |
Simulation of Remdesivir Pharmacokinetics and Its Drug Interactions.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; Computer Simulation; COVID-19; COVID-19 Drug Treatment; Databases, Chemical; Drug Interactions; Furans; Humans; Prodrugs; Pyrroles; Risk Assessment; Risk Factors; SARS-CoV-2; Triazines | 2021 |
Comparative bioavailability study following a single dose intravenous and buccal administration of remdesivir in rabbits.
Topics: Adenosine Monophosphate; Administration, Buccal; Administration, Intravenous; Alanine; Animals; Antiviral Agents; Biological Availability; COVID-19 Drug Treatment; Furans; Humans; Pyrroles; Rabbits; SARS-CoV-2; Triazines | 2022 |
Interpatient variability in the pharmacokinetics of remdesivir and its main metabolite GS-441524 in treated COVID-19 subjects.
Topics: Adenosine; Adenosine Monophosphate; Alanine; Antiviral Agents; COVID-19 Drug Treatment; Humans; Pyrroles; SARS-CoV-2; Tandem Mass Spectrometry; Transaminases; Triazines | 2022 |