Page last updated: 2024-08-18

pyrroles and proline

pyrroles has been researched along with proline in 184 studies

Research

Studies (184)

TimeframeStudies, this research(%)All Research%
pre-199081 (44.02)18.7374
1990's11 (5.98)18.2507
2000's22 (11.96)29.6817
2010's52 (28.26)24.3611
2020's18 (9.78)2.80

Authors

AuthorsStudies
Ertel, JC; Isseroff, H1
Downing, SJ; Phang, JM; Smith, RJ; Williams, JA; Yeh, GC1
Phang, JM; Reddi, AH; Smith, RJ1
Frank, L; Williams, I1
Kurelec, B1
Adams, E; Heacock, AM3
Seifter, S; Wu, GY2
Gottikh, BP; Grokhovsky, SL; Gursky, GV; Krylov, AS; Zasedatelev, AS; Zhuze, AL1
Applegarth, DA; Dooley, KC1
Similä, S2
Grokhovskiĭ, SL; Gurskiĭ, GV; Krylov, AS; Zasedatelev, AS; Zhuze, AL1
Phang, JM; Smith, RJ1
Herzfeld, A; Knox, WE; Mezl, VA1
Applegarth, DA; Goodman, SI; Phang, JM; Shih, VE; Valle, D1
Granger, AS; Kowaloff, EM; Phang, JM1
Arst, HN; MacDonald, DW1
Cushman, DW; Dzwonczyk, S; Fung, W; Grover, GJ; Sleph, PG; Tobias, D; Wang, P1
Cami, B; Chippaux, M; Fons, M1
Nemoto, N; Sakurai, J1
Purkiss, P; Wajner, M; Wannmacher, CM1
Phang, JM1
Jones, ME1
Fleming, GA; Granger, AS; Phang, JM; Steel, G; Valle, D1
Lee, TC; Yen, GC1
Hagedorn, CH; Phang, JM2
Hagedorn, CH1
Kador, PF; Kinoshita, JH; Shiono, T1
Fisher, HF; Srinivasan, R1
Franks, FM; Ison, RR; Soh, KS1
Harington, JS; Marasas, LW1
Budzikiewicz, H; Herrmann, EG; Schlunegger, UP; Wiegrebe, W1
Goodman, SI; Phang, JM; Valle, DL1
Barton, H; Drawert, F1
Bascur de Medina, L; Hearn, WR; Tanaka, WK1
Qadri, SM; Williams, RP1
Brill, WJ; Newell, SL1
Lundgren, DW; Ogur, M; Yuen, S1
Fang, VS1
Downing, SJ; Phang, JM; Valle, D2
Alworth, WL; Keenan, MV1
Brown, SB; Goodman, SI; Mace, JW; Miles, BS; Teng, CC1
Gott, CL; Qadri, SM; Williams, RP1
Austic, RE; Nesheim, MC1
Lukens, LN; Reed, DE1
Pfäffli, P; Tamm, C1
Kong, YL; Scannell, J1
Charlesworth, D; Hollán, SR; Lehmann, H; Lorkin, PA; Miltényi, M; Szelényi, JG1
Antener, I; Mollica, F; Pavone, L1
Bernlohr, RW; Laishley, EJ1
Corbella, A; Gariboldi, P; Jommi, G; Mauri, F1
Avioli, LV; Birge, SJ; Scharp, C1
Brosemer, RW; Veerabhadrappa, PS1
Gershon, H; Parmegiani, R; Scala, A1
Harris, ED; LeRoy, EC; Sjoerdsma, A1
Chambers, P; Hill, DL1
Smith, RJ1
Fleming, GA; Granger, AS; Hagedorn, CH; Phang, JM1
Hagedorn, CH; Phang, JM; Yeh, GC2
Downing, SJ; Hagedorn, CH; Phang, JM; Smith, RJ; Williams, JA; Yeh, GC1
Matsuzawa, T1
Arai, H; Ikeda, Y; Kobayashi, N; Nishioka, H; Niwa, S; Tanaka, Y; Torizuka, M; Yamanaka, T; Yoshinaga, K1
Kato, S; Kawai, H; Matsuoka, M; Mochizuki, J; Odagawa, A; Shindo, K1
Jayaswal, RK; Kaenjak, A; Townsend, DE; Wilkinson, BJ1
Kawamura, N; Naganawa, H; Sawa, R; Sawa, T; Takahashi, Y; Takeuchi, T1
Lu, Q; Peng, Z; Verma, DP1
Maloy, S; Surber, MW1
Bräuner-Osborne, H; Conti, P; De Amici, M; De Micheli, C; De Sarro, G; Madsen, U; Rizzo, M; Stensbøl, TB; Toma, L1
Demuth, H; Mrestani-Klaus, C; Neubert, K; Stiebitz, B; Stöckel-Maschek, A1
Alte Da Veiga, L; Matos Beja, A; Paixão, JA; Ramos Silva, M; Rocha Gonsalves, AM; Sobral, AJ1
Farrant, RD; Langley, GJ; Mellor, JM; Mills, GA; Walker, V2
Gilbertson, SR; Lan, P1
Burkart, MD; Thomas, MG; Walsh, CT1
Huong, NT; Inatomi, H; Yoshihashi, T1
Harada, T; Matsuda, T; Nagasawa, T; Nakamura, K; Ohashi, Y; Yanagihara, R1
VOGEL, HJ; YURA, T1
GREENBERG, DM; SMITH, ME1
BOUTHILLIER, LP; LETELLIER, G1
STRECKER, HJ2
MEISTER, A; RADHAKRISHNAN, AN1
ADAMS, E; GOLDSTONE, A3
SKURSKY, L1
ALTMAN, KI; GERBER, GB; TRAELNES, KR; WOOD, D1
HARRINGTON, WF; JOSSE, J1
EBERT, PS; PROCKOP, DJ; SHAPIRO, BM1
ALTMAN, KI; KONNO, K; TRAELNES, KR1
CLAMP, JR; HOUGH, L1
KARIYONE, K1
MACHOLAN, L1
PEISACH, J; STRECKER, HJ1
Christiaans, JA; Forsberg, MM; Gynther, J; Jarho, EM; Männistö, PT; Venäläinen, JI; Wallén, EA1
Jeannotte, G; Lubell, WD1
Al-Mourabit, A; Travert, N1
Brosnan, ME; Haslett, MR; Pink, D; Walters, B1
Koelsch, R; Neubert, K; Stiebitz, B; Stöckel-Maschek, A1
Brown, ZZ; Levins, CG; Schafmeister, CE1
Dorrestein, PC; Garneau-Tsodikova, S; Kelleher, NL; Walsh, CT1
Limbach, M1
Al-Mourabit, A; Appenzeller, J; Debitus, C; Martin, MT; Ratinaud, C; Vergne, C; Zaparucha, A1
Fang, ZF; Li, XP; Liu, QM; Qiu, SF; Shen, XQ; Zhang, M; Zhao, SP; Zhou, SH1
Mills, GA; Walker, V1
Brandi, A; Cordero, FM; de Meijere, A; Salvati, M; Vurchio, C1
Honig, A; Miller, G; Mittler, R; Stein, H; Suzuki, N; Zilberstein, A1
Ribeiro da Silva, MA; Santos, AF1
Cremonesi, G; Dalla Croce, P; Fontana, F; La Rosa, C1
Bazer, FW; Burghardt, RC; Johnson, GA; Kim, SW; Knabe, DA; Li, P; Li, X; McKnight, JR; Satterfield, MC; Spencer, TE; Wu, G1
Deutch, CE1
Baumer, A; Baumgartner, M; Bozorgmehr, B; Giunta, C; Häberle, J; Hausser, I; Kariminejad, A; Kariminejad, MH; Kretz, R; Rohrbach, M1
Gentilucci, L; Mosconi, E; Paradisi, E; Tolomelli, A; Viola, A1
Forseth, RR; Hale, KJ; Heemstra, JR; Jiang, W; Manaviazar, S; Neumann, CS; Schroeder, FC; Walsh, CT1
Csonka, LN; Eilenberg, H; Erster, O; Honig, A; Koncz, C; Miller, G; Stein, H; Szabados, L; Zilberstein, A1
Clark, BR; Fox, D; Leroy, J; Murphy, CD; O'Connor, S1
Al Mourabit, A; Cachet, N; Genta-Jouve, G; Holderith, S; Jeffree, R; Oberhänsli, F; Teyssié, JL; Thomas, OP1
Aryal, N; Bhattarai, S; Koju, D; Lamichhane, J; Maharjan, S; Sohng, JK1
Chikae, M; Takamura, Y; Truong, LT; Ukita, Y1
Kawakami, R; Ohshima, T; Sakuraba, H; Satomura, T1
Bao, H; Cheng, C; Cheng, G; Hu, Y; Liu, N; Wang, X1
Mysore, KS; Senthil-Kumar, M1
Baboo, V; Kumar, A; Rawat, P; Singh, RN; Verma, D1
Benecke, A; Boulkroun, S; Eilebrecht, S; Golib Dzib, JF; Hütt, MT; Lesne, A; Sonnenschein, N; Zennaro, MC1
Akram, NA; Ashraf, M; Jamil, A; Saadia, M1
Nasuno, R; Nishimura, A; Takagi, H1
Brandi, A; Cordero, FM; Lumini, M; Vurchio, C1
Borisov, AV; Gorobets, NY; Kovalenko, SM; Nechayev, MA; Tolmachev, AA1
Kim, GB; Nam, YW1
Filimonov, VO; Maslivets, AN; Silaichev, PS; Slepukhin, PA1
Jane, WN; Kumar, MN; Verslues, PE1
Butterton, JR; Feng, HP; Gupta, S; Hulskotte, EG; O'Mara, E; van Zutven, MG; Wagner, JA; Xuan, F1
Blank, I; Davidek, T; Dufossé, T; Festring, D; Novotny, O1
Kiefl, J; Pollner, G; Schieberle, P1
Bremer, E; Flórez, LA; Hoffmann, T; Stülke, J; Wünsche, G; Zaprasis, A1
Cvikrová, M; Gemperlová, L; Martincová, O; Vanková, R1
Khamarui, S; Maiti, DK; Samanta, S; Sengupta, T1
Alvarez, ME; Cecchini, NM; Hajirezaei, MR; Monteoliva, MI; Rizzi, YS1
Císařová, I; Jahn, U; Kapras, V; Pohl, R1
Batchu, VR; Boto, A; Miguélez, J; Romero-Estudillo, I1
Huang, SY; Jhang, WF; Manjappa, KB; Yang, DY1
Imbri, D; Jung, P; Kammer, LM; Kretzschmann, A; Kucukdisli, M; Netz, N; Opatz, T1
Dubey, G; Mohan Prasad, S; Pratap Singh, V; Singh, M1
Barrett, MP; Bütikofer, P; de Macêdo, JP; Mäser, P; Niemann, M; Roditi, I; Schneider, A; Schumann Burkard, G; Vial, H1
AbdElgawad, H; Asard, H; Beemster, GT; De Vos, D; Domagalska, MA; Zinta, G1
Kad, TD; Kaikavoosi, K; Nadaf, AB; Zanan, RL1
Sharma, V; Singh, V; Tripathi, BN1
Baraket, A; Elaissari, A; Errachid, A; Fessi, H; Kabbaj, D; Kunita, MH; Tenório-Neto, ET; Zine, N1
Ashraf, U; Duan, M; Huang, J; Mo, Z; Pan, S; Tang, X; Tian, H; Xiao, D; Xiao, L; Zhong, K1
Anjum, SA; Ashraf, U; Duan, M; Li, M; Mo, Z; Pan, S; Tang, X; Tian, H1
Arentson, BW; Becker, DF; Hayes, EL; Singh, H; Tanner, JJ; Zhu, W1
Brimble, MA; Furkert, DP; Wood, JM1
Aleksza, D; Horváth, GV; Sándor, G; Szabados, L1
Monza, J; Signorelli, S1
Renata, H; Zwick, CR1
Dadshani, S; Léon, J; Muzammil, S; Naz, AA; Pillen, K; Shrestha, A; Siddique, S1
Blume, C; Laxa, M; Mühlenbruch, M; Ost, J; Peterhänsel, C1
Chennaiah, A; Dubbu, S; Vankar, YD; Verma, AK1
Du, B; Du, P; He, J; Hu, L; Luo, H; Mao, T1
Burkart, MD; Corpuz, JC; Davis, TD; Jaremko, MJ1
Du, B; He, L; Luo, H; Pan, S; Tang, X; Zheng, A1
Anton, DB; Coelho, APD; Dillenburg, LR; Duarte, GL; Guzman, FL; Krause, FA; Kulcheski, FR; Margis, R; Turchetto-Zolet, AC; Vetö, NM1
Bashiri, G; Gazak, R; Janata, J; Kadlcik, S; Kamenik, Z; Kuzma, M; Man, P; Pavlikova, M; Steiningerova, L1
Ashraf, U; Huang, Z; Kong, L; Li, W; Li, Y; Liu, X; Mo, Z; Tang, X; Wang, S; Wu, L; Xie, W1
Avila, CC; Damasceno, FS; Elias, MC; Mantilla, BS; Marchese, L; Olavarria, K; Silber, AM; Souza, ROO1
Ferrario, E; Ferraris, DM; Miggiano, R; Rizzi, M1
Alazmi, M; Ann, NU; Chotana, GA; Emwas, AH; Fatima, S; Gao, X; Ibrar, M; Kanwal, S; Saleem, RSZ1
Boitrel, B; Le Gac, S1
He, L; Lai, R; Liu, J; Luo, H; Tang, X; Xing, P; Zhang, T; Zheng, A1
Ali, KH; Duan, M; Hussain, S; Imran, M; Pan, S; Potcho, MP; Rana, MS; Rasul, F; Saleem, MH; Tang, X1
Chen, Y; He, L; Luo, H; Tang, X1
Chalecka, M; Kazberuk, A; Palka, J; Surazynski, A1
Becker, DF; Patel, SM; Seravalli, J; Stiers, KM; Tanner, JJ1
Acharya, A; Agarwal, V; Gumbart, JC; Pavlova, A; Yi, D1
Ansari, Z; Barvkar, VT; Nadaf, AB; Renuka, N; Wang, C; Zhang, Y; Zhao, C1
Duan, M; Luo, H; Tang, X; Xie, H; Xing, P1
Blin, K; Charusanti, P; Genilloud, O; Gotfredsen, CH; Gren, T; Jørgensen, TS; Klitgaard, AK; Larsen, TO; Mohite, OS; Mourched, AS; Nielsen, JB; Oves-Costales, D; Tanner, D; Weber, T1
Boltje, TJ; Coene, KLM; Engelke, UFH; Hendriks, V; Huigen, MCDG; Körver-Keularts, IMLW; Martens, J; Mecinović, J; Merx, J; Oomens, J; Rutjes, FPJT; van Outersterp, RE; Waterval, HWAH; Wevers, RA1

Reviews

6 review(s) available for pyrroles and proline

ArticleYear
The regulatory functions of proline and pyrroline-5-carboxylic acid.
    Current topics in cellular regulation, 1985, Volume: 25

    Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship

1985
5-(pyrrolidin-2-yl)-1H-tetrazole and 5-[(pyrrolidin-2-yl)methyl]-1H-tetrazole: proline surrogates with increased potential in asymmetric catalysis.
    Chemistry & biodiversity, 2006, Volume: 3, Issue:2

    Topics: Catalysis; Proline; Pyrroles; Pyrrolidines; Stereoisomerism; Tetrazoles

2006
Proline and hydroxyproline metabolism: implications for animal and human nutrition.
    Amino acids, 2011, Volume: 40, Issue:4

    Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Birds; Chickens; Collagen; Diet; Dietary Supplements; Fishes; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Infant; Infant, Newborn; Milk; Nutritional Requirements; Proline; Pyrroles; Swine

2011
L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application.
    Applied microbiology and biotechnology, 2012, Volume: 93, Issue:1

    Topics: Amino Acid Sequence; Archaea; Coenzymes; Models, Molecular; Molecular Sequence Data; Proline; Proline Oxidase; Protein Multimerization; Protein Subunits; Pyrroles

2012
Type II non-ribosomal peptide synthetase proteins: structure, mechanism, and protein-protein interactions.
    Natural product reports, 2020, 03-25, Volume: 37, Issue:3

    Topics: Amino Acids; Benzoic Acid; Cyclopropanes; Hydroxylation; Lactams; Macrolides; Netropsin; Peptide Synthases; Proline; Protein Interaction Maps; Pyrroles; Thiazoles; Thiones

2020
P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis.
    International journal of molecular sciences, 2021, Oct-29, Volume: 22, Issue:21

    Topics: Amino Acids; Animals; Apoptosis; Cell Survival; Humans; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles

2021

Other Studies

178 other study(ies) available for pyrroles and proline

ArticleYear
Proline in fascioliasis: III. Activities of pyrroline-5-carboxylic acid reductase and pyrroline-5-carboxylic acid dehydrogenase in Fasciola.
    International journal for parasitology, 1976, Volume: 6, Issue:2

    Topics: Animals; Carboxylic Acids; Fasciola hepatica; Hydrogen-Ion Concentration; Liver; NAD; NADP; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Rabbits; Rats

1976
Stimulation of the hexose-monophosphate pentose pathway by delta 1-pyrroline-5-carboxylic acid in human fibroblasts.
    Biochemical and biophysical research communications, 1979, Mar-30, Volume: 87, Issue:2

    Topics: Cells, Cultured; Fibroblasts; Glucose; Hexosephosphates; Humans; NADP; Oxidation-Reduction; Pentoses; Proline; Pyrroles; Pyrroline Carboxylate Reductases

1979
Changes in proline synthetic and degradative enzymes during matrix-induced cartilage and bone formation.
    Calcified tissue international, 1979, Jul-03, Volume: 27, Issue:3

    Topics: Animals; Arginase; Bone and Bones; Bone Development; Bone Matrix; Cartilage; Male; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats

1979
Improved chemical synthesis and enzymatic assay of delta-1-pyrroline-5-carboxylic acid.
    Analytical biochemistry, 1975, Volume: 64, Issue:1

    Topics: Amines; Benzaldehydes; Carboxylic Acids; Colorimetry; Escherichia coli; Hydroxylysine; Oxidoreductases Acting on CH-NH Group Donors; Periodic Acid; Proline; Pyrroles; Stereoisomerism

1975
Catabolic path of arginine and NAD regeneration in the parasite Fasciola hepatica.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1975, Jun-15, Volume: 51, Issue:2

    Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Radioisotopes; Carboxylic Acids; Cytosol; Dogs; Fasciola hepatica; Glutamates; Ketoglutaric Acids; Mitochondria; NAD; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroles; Pyruvates; Urea

1975
Formation and excretion of pyrrole-2-carboxylic acid. Whole animal and enzyme studies in the rat.
    The Journal of biological chemistry, 1975, Apr-10, Volume: 250, Issue:7

    Topics: Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Animals; Carboxylic Acids; Catalase; Cattle; Chromatography, Ion Exchange; D-Amino-Acid Oxidase; Guinea Pigs; Humans; Hydroxyproline; Kidney; Kinetics; Leucine; Liver; Proline; Pyrroles; Rats; Swine

1975
A new method for the preparation of delta 1-pyrroline 5-carboxylic acid and proline.
    Analytical biochemistry, 1975, Volume: 67, Issue:2

    Topics: Amino Acids; Carboxylic Acids; Chemical Phenomena; Chemistry; Cyclization; Glutarates; Hydrogen-Ion Concentration; Hydroxylysine; Proline; Pyrroles

1975
Quantitative estimation of the contribution of pyrrolcarboxamide groups of the antibiotic distamycin A into specificity of its binding to DNA AT pairs.
    Nucleic acids research, 1979, Volume: 6, Issue:1

    Topics: Adenine; Chemical Phenomena; Chemistry; Circular Dichroism; Dansyl Compounds; Distamycins; DNA; Ligands; Nucleic Acid Conformation; Polydeoxyribonucleotides; Proline; Pyrroles; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thermodynamics; Thymine

1979
Hyperprolinemia type II: evidence of the excretion of 3-hydroxy delta 1-pyrroline 5-carboxylic acid.
    Clinical biochemistry, 1979, Volume: 12, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography, Ion Exchange; Chromatography, Paper; Humans; Proline; Pyrroles

1979
Hydroxyproline metabolism in type II hyperprolinaemia.
    Annals of clinical biochemistry, 1979, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Female; Glycine; Humans; Hydroxyproline; Male; Metabolic Clearance Rate; Ornithine; Proline; Pyrroles

1979
[Quantitative assessment of the contribution of the pyrrolcarboxamide groups in distamycin A antibiotic in achieving its binding specificity with DNA AT-pairs].
    Doklady Akademii nauk SSSR, 1978, Volume: 239, Issue:3

    Topics: Adenine; Adsorption; Dansyl Compounds; Distamycins; DNA; Proline; Protein Binding; Pyrroles; Spectrometry, Fluorescence; Structure-Activity Relationship; Thymine

1978
Proline metabolism in cartilage: the importance of proline biosynthesis.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:6

    Topics: Cartilage; Culture Techniques; Glutamates; Kidney; Liver; Models, Biological; Ornithine; Proline; Pyrroles; Xiphoid Bone

1978
Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues.
    The Biochemical journal, 1977, Jul-15, Volume: 166, Issue:1

    Topics: Animals; Fetus; Neoplasms, Experimental; Oxidoreductases; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Stereoisomerism; Temperature

1977
Type II hyperprolinemia. Delta1-pyrroline-5-carboxylic acid dehydrogenase deficiency in cultured skin fibroblasts and circulating lymphocytes.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Carboxylic Acids; Cells, Cultured; Female; Fibroblasts; Humans; In Vitro Techniques; Leukocytes; Lymphocytes; Male; Oxidoreductases; Pedigree; Proline; Pyrroles; Skin

1976
Alterations in proline metabolic enzymes with mammalian development.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:10

    Topics: Aging; Animals; Carboxylic Acids; Female; Kidney; Kinetics; Leucine; Liver; Mitochondria, Liver; Organ Specificity; Oxidoreductases; Oxygenases; Pregnancy; Proline; Pyrroles; Rats; Stereoisomerism; Valine

1976
A gene cluster in Aspergillus nidulans with an internally located cis-acting regulatory region.
    Nature, 1975, Mar-06, Volume: 254, Issue:5495

    Topics: Amino Acid Oxidoreductases; Aspergillus nidulans; Carbon; Carboxylic Acids; Chromosome Mapping; Crosses, Genetic; Enzyme Repression; Genes; Genes, Regulator; Genetic Linkage; Genotype; Mutation; Operon; Ornithine; Oxidoreductases; Proline; Pyrroles

1975
Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Coronary Disease; Drug Stability; Enalaprilat; Fosinopril; Heart; In Vitro Techniques; Male; Myocardium; Organophosphorus Compounds; Prodrugs; Proline; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1991
Possible involvement of a L-delta 1-pyrroline-5-carboxylate (P5C) reductase in the synthesis of proline in Desulfovibrio desulfuricans Norway.
    Biochemical and biophysical research communications, 1991, Sep-16, Volume: 179, Issue:2

    Topics: Desulfovibrio; DNA, Bacterial; Enzyme Stability; Escherichia coli; Gene Expression; Genotype; Hot Temperature; Plasmids; Proline; Pyrroles

1991
Proline is required for transcriptional control of the aromatic hydrocarbon-inducible P(1)450 gene in C57BL/6 mouse monolayer-cultured hepatocytes.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Mice; Mice, Inbred C57BL; Ornithine; Polycyclic Compounds; Proline; Pyrroles; RNA, Messenger; Transcription, Genetic

1991
High urinary excretion of N-(pyrrole-2-carboxyl) glycine in type II hyperprolinemia.
    Clinical genetics, 1990, Volume: 37, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Consanguinity; Electroencephalography; Glycine; Growth Disorders; Humans; Infant; Male; Proline; Pyrroles; Recurrence; Seizures

1990
Conversion of glutamate to ornithine and proline: pyrroline-5-carboxylate, a possible modulator of arginine requirements.
    The Journal of nutrition, 1985, Volume: 115, Issue:4

    Topics: Amino Acids; Animals; Arginine; Biotransformation; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Kidney; Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Retinal Degeneration; Spleen

1985
Periodate oxidation products of hydroxylysine in the synthesis of 5-substituted prolines.
    Analytical biochemistry, 1985, May-15, Volume: 147, Issue:1

    Topics: Hydrogen-Ion Concentration; Hydroxylysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Proline; Pyrroles; Spectrophotometry, Infrared; Temperature

1985
The aqueous humor of rabbit contains high concentrations of pyrroline-5-carboxylate.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:10

    Topics: Animals; Aqueous Humor; Guinea Pigs; Haplorhini; Male; Models, Chemical; Pigmentation; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits; Species Specificity; Tissue Distribution

1986
Mutagen formation in the reaction of Maillard browning products, 2-acetylpyrrole and its analogues, with nitrite.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1986, Volume: 24, Issue:12

    Topics: Animals; Chromatography, Thin Layer; Hydrogen-Ion Concentration; Mutagenicity Tests; Nitrites; Proline; Pyrroles; Rats; Salmonella typhimurium; Temperature

1986
Catalytic transfer of hydride ions from NADPH to oxygen by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
    Archives of biochemistry and biophysics, 1986, Volume: 248, Issue:1

    Topics: Adenosine Triphosphate; Animals; Humans; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxygen; Proline; Pyrroles; Rats

1986
Demonstration of a NADPH-linked delta 1-pyrroline-5-carboxylate-proline shuttle in a cell-free rat liver system.
    Biochimica et biophysica acta, 1986, Oct-29, Volume: 884, Issue:1

    Topics: Animals; Cell-Free System; Cold Temperature; Mitochondria, Liver; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Solubility

1986
Stimulation of the hexose monophosphate pathway by pyrroline-5-carboxylate reductase in the lens.
    Experimental eye research, 1985, Volume: 41, Issue:6

    Topics: Aging; Animals; Female; Glucose; Glutamine; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains

1985
Reversible reduction of an alpha-imino acid to an alpha-amino acid catalyzed by glutamate dehydrogenase: effect of ionizable functional groups.
    Biochemistry, 1985, Jan-29, Volume: 24, Issue:3

    Topics: Animals; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Mathematics; NADP; Oxidation-Reduction; Proline; Pyrroles

1985
Source of pyrrole-2-carboxylate in mammalian urine.
    Biochemical and biophysical research communications, 1973, Jan-23, Volume: 50, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Carboxylic Acids; Chick Embryo; Colorimetry; D-Amino-Acid Oxidase; Hydroxyproline; Intestines; Isomerism; Ketamine; Kidney; Male; Oxidation-Reduction; Oxidoreductases; Proline; Pyrroles; Rats; Tritium

1973
The binding of conformationally restricted antihistamines to histamine receptors.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:11

    Topics: Aminobutyrates; Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Molecular Conformation; Muscle Contraction; Muscle, Smooth; Proline; Pyrroles; Receptors, Drug; Spectrum Analysis; Stereoisomerism; Structure-Activity Relationship

1973
The in vitro hydroxylation of proline by silica powder.
    Environmental research, 1970, Volume: 3, Issue:3

    Topics: Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Hydroxyproline; Proline; Pyrroles; Silicon Dioxide; Surface Properties

1970
[Rearrangement of prolinol derivatives. 2. N-alkoxycarbonyl-prolinyl esters].
    Helvetica chimica acta, 1974, Volume: 57, Issue:2

    Topics: Esters; Mass Spectrometry; Mesylates; Oxazoles; Proline; Pyrroles

1974
Type 2 hyperprolinemia: absence of delta1-pyrroline-5-carboxylic acid dehydrogenase activity.
    Science (New York, N.Y.), 1974, Sep-20, Volume: 185, Issue:4156

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Carbon Radioisotopes; Carboxylic Acids; Child, Preschool; Female; Fibroblasts; Glutamates; Humans; Male; NAD; Ornithine; Oxidoreductases; Proline; Pyrroles

1974
Formation and excretion of pyrrole-2-carboxylate in man.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Animals; Carbon Radioisotopes; Carboxylic Acids; Chromatography, Ion Exchange; Female; Humans; Hydroxyproline; Male; Middle Aged; Proline; Pyrroles; Rats; Tritium

1974
[On the enzymatic analysis of hydroxyproline, I. Thin-layer chromatographic separation of L- and D-allo-hydroxyproline and several metabolic products of hydroxyproline (author's transl)].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1974, Volume: 355, Issue:7

    Topics: Chromatography, Thin Layer; Hydroxyproline; Indicators and Reagents; Ketoglutaric Acids; Proline; Pyrroles; Solvents; Stereoisomerism

1974
Labeling patterns in prodigiosin biosynthesis.
    Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; Genetics, Microbial; Glycine; Maleimides; Methionine; Mutation; Oxidation-Reduction; Pigments, Biological; Prodigiosin; Proline; Pyrroles; Serratia marcescens

1972
Induction of prodigiosin biosynthesis after shift-down in temperature of nonproliferating cells of Serratia marcescens.
    Applied microbiology, 1972, Volume: 23, Issue:4

    Topics: Amino Acids; Anti-Bacterial Agents; Bacteriological Techniques; Culture Media; Methionine; Pigments, Biological; Prodigiosin; Proline; Pyrroles; Serratia marcescens; Spectrophotometry; Stereoisomerism; Temperature

1972
Mutants of Salmonella typhimurium that are insensitive to catabolite repression of proline degradation.
    Journal of bacteriology, 1972, Volume: 111, Issue:2

    Topics: Ammonia; Carboxylic Acids; Crosses, Genetic; Culture Media; Enzyme Repression; Glucose; Glucosyltransferases; Histidine; Lyases; Maltose; Mutation; Oxidoreductases; Proline; Pyrroles; Salmonella typhimurium; Transduction, Genetic

1972
The isolation and characterization of a Saccharomyces mutant deficient in 1 -pyrroline- 5 -carboxylate dehydrogenase activity.
    Biochimica et biophysica acta, 1972, Dec-29, Volume: 286, Issue:2

    Topics: Amino Acid Oxidoreductases; Carbon Isotopes; Culture Media; Glutamates; Models, Biological; Mutation; Proline; Pyrroles; Saccharomyces

1972
Studies on the hypocalcemic action of 2-pyrrolecarboxylic acid.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 202, Issue:1

    Topics: Administration, Oral; Animals; Calcitonin; Calcium; Carboxylic Acids; Diet; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Male; Nephrectomy; Parathyroid Hormone; Phosphates; Proline; Pyrroles; Rats; Thiophenes

1973
A radioisotopic assay for delta1-pyrroline-5-carboxylate reductase.
    Analytical biochemistry, 1973, Volume: 55, Issue:1

    Topics: Carbon Radioisotopes; Carboxylic Acids; Chromatography, Ion Exchange; Evaluation Studies as Topic; Kinetics; Methods; Ornithine; Oxidoreductases; Proline; Pyrroles; Transaminases

1973
Proline inhibition of pyrroline-5-carboxylate reductase: differences in enzymes obtained from animal and tissue culture sources.
    Biochemical and biophysical research communications, 1973, Oct-15, Volume: 54, Issue:4

    Topics: Animals; Carbon Radioisotopes; Cattle; Cell Line; Cricetinae; Culture Techniques; Dialysis; Female; Fibroblasts; Humans; Kinetics; Liver; Lung; Ovary; Oxidoreductases; Proline; Proteins; Pyrroles

1973
The inhibition of proline racemase by a transition state analogue: delta-1-pyrroline-2-carboxylate.
    Biochemical and biophysical research communications, 1974, Mar-25, Volume: 57, Issue:2

    Topics: Amino Acid Isomerases; Binding Sites; Carboxylic Acids; Clostridium; Deuterium; Dithiothreitol; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Optical Rotation; Proline; Protein Binding; Protein Conformation; Pyrroles

1974
Defective hydroxyproline metabolism in type II hyperprolinemia.
    Biochemical medicine, 1974, Volume: 10, Issue:4

    Topics: Amines; Amino Acid Metabolism, Inborn Errors; Amino Acids; Benzaldehydes; Carboxylic Acids; Child; Chromatography, Ion Exchange; Female; Glycine; Humans; Hydroxyproline; Imino Acids; Proline; Pyrroles

1974
Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids.
    Journal of bacteriology, 1971, Volume: 106, Issue:2

    Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacteriological Techniques; Caseins; Culture Media; Filtration; Glutamates; Ornithine; Pigments, Biological; Prodigiosin; Proline; Protein Hydrolysates; Pyrroles; Serine; Serratia marcescens; Stereoisomerism; Temperature

1971
Arginine, ornithine and proline metabolism of chicks: influence of diet and heredity.
    The Journal of nutrition, 1971, Volume: 101, Issue:10

    Topics: Amino Acid Oxidoreductases; Amino Acids; Aminoisobutyric Acids; Animals; Arginase; Arginine; Chickens; Depression, Chemical; Diet; Glutamates; Histidine; Kidney; Liver; Lysine; Organ Specificity; Ornithine; Oxidoreductases; Proline; Pyrroles; Selection, Genetic; Species Specificity; Stimulation, Chemical; Threonine; Transaminases; Tyrosine

1971
Observations on the conversion of N-acetylglutamate to proline in extracts of Escherichia coli.
    The Journal of biological chemistry, 1966, Jan-25, Volume: 241, Issue:2

    Topics: Arginine; Escherichia coli; Glutamates; In Vitro Techniques; Molecular Biology; Mutation; Ornithine; Proline; Pyrroles

1966
[Biosynthesis of the antibiotic verrucarin E. Verrucarine and roridine. 19.1].
    Helvetica chimica acta, 1969, Volume: 52, Issue:7

    Topics: Anti-Bacterial Agents; Carbon Isotopes; Glutamates; Levulinic Acids; Mitosporic Fungi; Proline; Pyrroles

1969
Biosynthesis of coumermycin A1: incorporation of L-proline into the pyrrole groups.
    Antimicrobial agents and chemotherapy, 1969, Volume: 9

    Topics: Anti-Bacterial Agents; Coumarins; Proline; Pyrroles; Streptomyces

1969
Intravenous proline tolerance in a patient with hyperprolinaemia type II and his relatives.
    Helvetica paediatrica acta, 1970, Volume: 25, Issue:3

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Carboxylic Acids; Child; Female; Genetics, Medical; Heterozygote; Homozygote; Humans; Injections, Intravenous; Male; Proline; Pyrroles; Statistics as Topic

1970
Unstable haemoglobin disease caused by Hb Santa Ana- 88 (F4) Leu leads to Pro.
    Haematologia, 1970, Volume: 4, Issue:2

    Topics: Acetylcholinesterase; Adenosine Triphosphate; Amino Acid Sequence; Anemia, Hemolytic; Blood Group Antigens; Blood Protein Electrophoresis; Cell Membrane Permeability; Cell Survival; Chemistry Techniques, Analytical; Child; Chromium Isotopes; Electrophoresis, Disc; Electrophoresis, Paper; Erythrocytes, Abnormal; Erythropoiesis; Glucosephosphate Dehydrogenase; Glutathione; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Hungary; Immunogenetics; Iron Isotopes; Leucine; Lipids; Male; Mutation; Proline; Pyrroles

1970
Pure familial hyperprolinemia: isolated inborn error of aminoacid metabolism without other anomalies in a Sicilian family.
    Pediatrics, 1971, Volume: 48, Issue:2

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Glycine; Heterozygote; Humans; Infant; Male; Pedigree; Proline; Pyrroles

1971
Regulation of arginine and proline catabolism in Bacillus licheniformis.
    Journal of bacteriology, 1968, Volume: 96, Issue:2

    Topics: Acetates; Arginase; Arginine; Bacillus; Enzyme Induction; Enzyme Repression; Glucose; Glutamates; Glycerol; Oxidoreductases; Proline; Pyrroles; Pyruvates; Transaminases

1968
Synthesis of 3,4-dehydroproline.
    Chemistry & industry, 1969, May-03, Volume: 18

    Topics: Amino Acids; Chemical Phenomena; Chemistry; Proline; Pyrroles; Pyrrolidines

1969
Catabolism of free hydroxyproline in chronic uremia.
    The American journal of physiology, 1969, Volume: 217, Issue:2

    Topics: Adult; Animals; Humans; Hydroxyproline; Middle Aged; Proline; Pyrroles; Rats; Spectrum Analysis; Uremia

1969
Pathway of proline oxidation in insect flight muscle.
    Biochimica et biophysica acta, 1965, Oct-25, Volume: 110, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Dialysis; Enzymes; Glutamates; In Vitro Techniques; Insecta; Magnesium; Muscles; Oxidoreductases; Proline; Pyrroles; Subcellular Fractions

1965
Amino acid analogs. I. Analogs of the glutamic acid-proline interconversion. 3. Substituted 2-acetamido-4-benzoylbutyric acids and 5-phenylprolines.
    Journal of medicinal chemistry, 1965, Volume: 8, Issue:6

    Topics: Amino Acids; Amino Sugars; Animals; Biological Assay; Butyrates; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Glutamates; Leuconostoc; Leukemia L1210; Proline; Pyrroles; Sarcoma 180

1965
A modified procedure for radioactive hydroxyproline assay in urine and tissues after labeled proline administration.
    Analytical biochemistry, 1966, Volume: 17, Issue:3

    Topics: Animals; Arteries; Carbon Isotopes; Colorimetry; Hydroxyproline; Indicators and Reagents; Liver; Myocardium; Proline; Pyrroles; Rabbits; Rats; Semicarbazides; Skin; Solvents; Tendons; Toluene; Tritium

1966
The biosynthesis of proline by Tetrahymena pyriformis.
    Biochimica et biophysica acta, 1967, Nov-28, Volume: 148, Issue:2

    Topics: Acids; Alanine; Arginine; Carbon Isotopes; Citrulline; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydrolases; Ketoglutaric Acids; Kinetics; Metals; Ornithine; Oxidoreductases; Proline; Protein Denaturation; Pyrroles; Tetrahymena; Transaminases; Ureohydrolases; Valine

1967
A radioisotopic assay for delta 1-pyrroline-5-carboxylate synthase activity.
    Enzyme, 1984, Volume: 31, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cell Line; Cricetinae; Glutamates; Glutamic Acid; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Transaminases

1984
Transfer of reducing equivalents into mitochondria by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
    Archives of biochemistry and biophysics, 1983, Volume: 225, Issue:1

    Topics: Animals; Catalysis; Cell-Free System; Cytosol; Glucose; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Male; Mitochondria, Liver; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains

1983
Pyrroline-5-carboxylate in human plasma.
    Metabolism: clinical and experimental, 1984, Volume: 33, Issue:8

    Topics: Chromatography, Ion Exchange; Female; Humans; Male; Methods; Proline; Pyrroles; Saliva

1984
The intercellular proline cycle.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Animals; Erythrocytes; Humans; Liver; Mice; Mitochondria, Liver; NADP; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases

1981
Stimulation of the hexosemonophosphate-pentose pathway by pyrroline-5-carboxylate in cultured cells.
    Journal of cellular physiology, 1982, Volume: 110, Issue:3

    Topics: Animals; Cell Line; Cells, Cultured; Citric Acid Cycle; Cricetinae; Female; Fibroblasts; Glucose; Hexosephosphates; Humans; Kidney; NADP; Ovary; Oxidation-Reduction; Pentoses; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits

1982
Transfer of 1-pyrroline-5-carboxylate as oxidizing potential from hepatocytes to erythrocytes.
    The Biochemical journal, 1982, Jan-15, Volume: 202, Issue:1

    Topics: Animals; Erythrocytes; Humans; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Pentosephosphates; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Inbred Strains; Stimulation, Chemical

1982
Disease of the ornithine-proline pathway: delta 1-pyrroline-5-carboxylate reductase deficiency in the retina of retinal degeneration mice.
    Metabolic, pediatric, and systemic ophthalmology, 1982, Volume: 6, Issue:2

    Topics: Animals; Cattle; Eye; Liver; Mice; Mice, Inbred Strains; Ornithine; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Retinal Degeneration; Weaning

1982
New potent prolyl endopeptidase inhibitors: synthesis and structure-activity relationships of indan and tetralin derivatives and their analogues.
    Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13

    Topics: Animals; Brain; Dogs; In Vitro Techniques; Indans; Magnetic Resonance Spectroscopy; Proline; Prolyl Oligopeptidases; Pyrroles; Serine Endopeptidases; Serine Proteinase Inhibitors; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrahydronaphthalenes

1994
Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties.
    The Journal of antibiotics, 1993, Volume: 46, Issue:6

    Topics: Animals; Brain; Fermentation; Hypoxia; Lipid Peroxidation; Male; Mice; Proline; Pyrroles; Rats; Rats, Wistar; Streptomyces

1993
Proline is biosynthesized from arginine in Staphylococcus aureus.
    Microbiology (Reading, England), 1996, Volume: 142 ( Pt 6)

    Topics: Arginine; Bacterial Proteins; Carbon; DNA Transposable Elements; Glutamic Acid; Ornithine; Proline; Pyrroles; Staphylococcus aureus

1996
Pyralomicins, novel antibiotics from Microtetraspora spiralis. III. Biosynthesis of pyralomicin 1a.
    The Journal of antibiotics, 1996, Volume: 49, Issue:7

    Topics: Acetates; Actinomycetales; Anti-Bacterial Agents; Benzopyrans; Carbon; Chromones; Glucose; Magnetic Resonance Spectroscopy; Proline; Pyrroles

1996
Reciprocal regulation of delta 1-pyrroline-5-carboxylate synthetase and proline dehydrogenase genes controls proline levels during and after osmotic stress in plants.
    Molecular & general genetics : MGG, 1996, Dec-13, Volume: 253, Issue:3

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Sequence; Animals; Arabidopsis; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Molecular Sequence Data; Osmotic Pressure; Oxidoreductases Acting on CH-NH Group Donors; Proline; Proline Oxidase; Pyrroles; RNA, Messenger; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Transcription, Genetic; Water

1996
The PutA protein of Salmonella typhimurium catalyzes the two steps of proline degradation via a leaky channel.
    Archives of biochemistry and biophysics, 1998, Jun-15, Volume: 354, Issue:2

    Topics: Bacterial Proteins; Binding, Competitive; Catalysis; Kinetics; Membrane Proteins; NAD; Proline; Proline Oxidase; Pyrroles; Salmonella typhimurium; Substrate Specificity

1998
Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Animals; Cerebral Cortex; Convulsants; Excitatory Amino Acid Agonists; In Vitro Techniques; Isoxazoles; Male; Mice; Mice, Inbred DBA; Models, Molecular; Molecular Conformation; Proline; Pyrroles; Radioligand Assay; Rats; Receptors, AMPA; Receptors, Kainic Acid; Stereoisomerism

1999
Thioxo amino acid pyrrolidides and thiazolidides: new inhibitors of proline specific peptidases.
    Biochimica et biophysica acta, 2000, Jun-15, Volume: 1479, Issue:1-2

    Topics: Amino Acids; Animals; Dipeptidyl Peptidase 4; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Proline; Protease Inhibitors; Pyrroles; Substrate Specificity; Swine; Thiazoles

2000
Benzyl 5-carboxy-4-ethyl-3-methylpyrrole-2-carboxylate.
    Acta crystallographica. Section C, Crystal structure communications, 2000, Volume: 56 ( Pt 10)

    Topics: Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Proline; Pyrroles

2000
Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: Aldehydes; Avitaminosis; Chromatography, High Pressure Liquid; Humans; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Proline; Pyridoxal Phosphate; Pyridoxine; Pyrroles; Seizures

2001
Kinetic resolution in palladium-catalyzed asymmetric allylic alkylations by a P,O ligand system.
    Organic letters, 2001, Jul-12, Volume: 3, Issue:14

    Topics: Acetates; Catalysis; Chromatography, High Pressure Liquid; Cyclization; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Oxazoles; Palladium; Peptides; Phosphines; Proline; Pyrroles; Stereoisomerism; Structure-Activity Relationship

2001
Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis.
    Chemistry & biology, 2002, Volume: 9, Issue:2

    Topics: Amino Acyl-tRNA Synthetases; Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Catalysis; Escherichia coli; Genes, Bacterial; Multigene Family; Phenols; Prodigiosin; Proline; Protein Structure, Tertiary; Pseudomonas fluorescens; Pyrroles; Streptomyces; Substrate Specificity

2002
Precursors of 2-acetyl-1-pyrroline, a potent flavor compound of an aromatic rice variety.
    Journal of agricultural and food chemistry, 2002, Mar-27, Volume: 50, Issue:7

    Topics: Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Indicator Dilution Techniques; Nitrogen Isotopes; Ornithine; Oryza; Plant Leaves; Plant Structures; Proline; Pyrroles; Taste

2002
Conversion of pyrrole to pyrrole-2-carboxylate by cells of Bacillus megaterium in supercritical CO2.
    Chemical communications (Cambridge, England), 2001, Nov-07, Issue:21

    Topics: Bacillus megaterium; Carbon Dioxide; Catalysis; Chromatography, High Pressure Liquid; Proline; Pyrroles; Temperature; Time Factors

2001
A novel pyrroline-5-carboxylic acid and acetoacetic acid adduct in hyperprolinaemia type II.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 331, Issue:1-2

    Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Child; Female; Gas Chromatography-Mass Spectrometry; Humans; Proline; Pyridoxal Phosphate; Pyrroles; Stereoisomerism

2003
On the biosynthesis of proline in Neurospora crassa: enzymic reduction of delta1-pyrroline-5-carboxylate.
    Biochimica et biophysica acta, 1955, Volume: 17, Issue:4

    Topics: Neurospora; Neurospora crassa; Proline; Pyrroles

1955
Characterization of an enzyme reducing pyrroline-5-carboxylate to proline.
    Nature, 1956, Jun-16, Volume: 177, Issue:4520

    Topics: Humans; Liver; Oxidoreductases; Proline; Pyrroles

1956
The formation of 2-pyrrolecarboxylic acid from hydroxy-D- and allohydroxy-D-proline.
    Canadian journal of biochemistry and physiology, 1956, Volume: 34, Issue:6

    Topics: Proline; Pyrroles

1956
The interconversion of glutamic acid and proline. I. The formation of delta1-pyrroline-5-carboxylic acid from glutamic acid in Escherichia coli.
    The Journal of biological chemistry, 1957, Volume: 225, Issue:2

    Topics: Carboxylic Acids; Escherichia coli; Glutamates; Glutamic Acid; Proline; Pyrroles

1957
Conversion of hydroxyproline to pyrrole-2-carboxylic acid.
    The Journal of biological chemistry, 1957, Volume: 226, Issue:1

    Topics: Hydroxyproline; Proline; Pyrroles

1957
Hydroxyproline metabolism. II. Enzymatic preparation and properties of Delta 1-pyrroline-3-hydroxy-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. III. Enzymatic synthesis of hydroxyproline from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Amino Acids; Glutamates; Hydroxyproline; Proline; Pyrroles

1960
The interconversion of glutamic acid and proline. II. The preparation and properties of delta 1-pyrroline-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1960
[Oxydation of proline by periodate and isolation of 1-pyrroline].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1959, Volume: 14B

    Topics: Oxidation-Reduction; Periodic Acid; Proline; Pyrroles

1959
THE QUANTITATIVE DETERMINATION OF PYRROLE-2-CARBOXYLIC ACID IN URINE.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Body Fluids; Carbon Isotopes; Proline; Pyrroles; Rats; Research; Spectrophotometry; Urine

1964
ROLE OF PYRROLIDINE RESIDUES IN THE STRUCTURE AND STABILIZATION OF COLLAGEN.
    Journal of molecular biology, 1964, Volume: 9

    Topics: Amino Acids; Animals; Annelida; Ascaris; Chemical Phenomena; Chemistry; Cold Temperature; Collagen; Gelatin; Hot Temperature; Proline; Pyrroles; Pyrrolidines; Research

1964
STUDIES WITH PROLINE-3,4,-H3 ON THE HYDROXYLATION OF PROLINE DURING COLLAGEN SYNTHESIS IN CHICK EMBRYOS.
    Archives of biochemistry and biophysics, 1964, Jul-20, Volume: 106

    Topics: Animals; Carbon Isotopes; Chick Embryo; Chromatography; Collagen; Glutamates; Hydroxylation; Hydroxyproline; Proline; Proteins; Pyrroles; Research; Tritium

1964
THE EFFECT OF WHOLE- AND PARTIAL-BODY X-IRRADIATION ON THE METABOLISM OF COLLAGEN IN POLYETHYLENE SPONGES AND THE URINARY EXCRETION OF PYRROLE-2-CARBOXYLIC ACID.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1964, Volume: 8

    Topics: Animals; Carbon Isotopes; Chromatography; Collagen; Fluids and Secretions; Glycine; Hydroxyproline; Polyethylene; Polyethylenes; Porifera; Proline; Proteins; Pyrroles; Radiation Effects; Rats; Research; Urine

1964
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
    The Biochemical journal, 1965, Volume: 94

    Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine

1965
[Studies on insecticides. VIII. Synthesis of 5-methyl-3-pyrrolidinecarboxylic acid].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Insecticides; Proline; Pyrroles

1962
[Photometric determination of alpha-keto-delta-aminovaleric acid (delta1-pyrroline-2-carboxylic acid) and prolines].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1962, Aug-06, Volume: 328

    Topics: Amino Acids; Amino Acids, Neutral; Carboxylic Acids; Proline; Pyrroles; Valine

1962
The interconversion of glutamic acid and proline. V. The reduction of delta 1-pyrroline-5-carboxylic acid to proline.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1962
New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Animals; Brain; Indicators and Reagents; Magnetic Resonance Spectroscopy; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Pyrroles; Pyrrolidines; Serine Endopeptidases; Structure-Activity Relationship; Swine

2003
Synthesis of fused heteroarylprolines and pyrrolopyrroles.
    The Journal of organic chemistry, 2004, Jul-09, Volume: 69, Issue:14

    Topics: Combinatorial Chemistry Techniques; Indicators and Reagents; Molecular Structure; Oxidation-Reduction; Phenylalanine; Proline; Pyrroles; Stereoisomerism; Structure-Activity Relationship

2004
A likely biogenetic gateway linking 2-aminoimidazolinone metabolites of sponges to proline: spontaneous oxidative conversion of the pyrrole-proline-guanidine pseudo-peptide to dispacamide A.
    Journal of the American Chemical Society, 2004, Aug-25, Volume: 126, Issue:33

    Topics: Amination; Animals; Biomimetic Materials; Guanidine; Imidazoles; Oxidation-Reduction; Peptides; Porifera; Proline; Pyrroles

2004
Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.
    Biochimica et biophysica acta, 2004, Nov-18, Volume: 1675, Issue:1-3

    Topics: Animals; Glutamic Acid; Liver; Male; Mitochondria; NADP; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions; Ultracentrifugation

2004
Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: Synthesis and kinetic characterization as aminopeptidase P inhibitors.
    Bioorganic & medicinal chemistry, 2005, Aug-15, Volume: 13, Issue:16

    Topics: Amino Acids; Aminopeptidases; Animals; Binding Sites; Escherichia coli; Kinetics; Leucine; Proline; Protease Inhibitors; Pyrroles; Rats; Structure-Activity Relationship; Substrate Specificity; Thiazoles

2005
Maximizing the stereochemical diversity of spiro-ladder oligomers.
    Organic letters, 2006, Jun-22, Volume: 8, Issue:13

    Topics: Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polymers; Proline; Pyrroles; Spiro Compounds; Stereoisomerism

2006
Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J.
    Journal of the American Chemical Society, 2006, Oct-04, Volume: 128, Issue:39

    Topics: Carrier Proteins; Escherichia coli; Mass Spectrometry; Phenylpropionates; Prodigiosin; Proline; Pyrroles; Recombinant Proteins; Serratia

2006
Debromodispacamides B and D: isolation from the marine sponge Agelas mauritiana and stereoselective synthesis using a biomimetic proline route.
    Organic letters, 2008, Feb-07, Volume: 10, Issue:3

    Topics: Agelas; Animals; Imidazoles; Marine Biology; Molecular Structure; Proline; Pyrroles; Stereoisomerism

2008
Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:5

    Topics: Antioxidants; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Nucleus; Cells, Cultured; Cytoplasm; Down-Regulation; Drug Interactions; Endothelial Cells; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Malondialdehyde; Proline; Pyrroles; RNA, Messenger; Superoxide Dismutase; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta; Umbilical Veins

2008
N-(pyrrole-2-carboxyl) glycine a diagnostic marker of hyperprolinaemia type II: mass spectra of trimethylsilyl derivatives.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 405, Issue:1-2

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Biomarkers; Child; Glycine; Humans; Hydroxyproline; Mass Spectrometry; Metabolism, Inborn Errors; Proline; Pyrroles; Trimethylsilyl Compounds

2009
Synthesis of alpha-cyclopropyl-beta-homoprolines.
    The Journal of organic chemistry, 2009, Jun-05, Volume: 74, Issue:11

    Topics: Amino Acids, Cyclic; Oligopeptides; Proline; Pyrroles; Stereoisomerism

2009
Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Arabidopsis; Arabidopsis Proteins; Droughts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamic Acid; Hot Temperature; Medicago sativa; Mitochondria; Mutation; Nicotiana; Oxidation-Reduction; Plants; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride

2009
Experimental and computational study on the molecular energetics of 2-pyrrolecarboxylic acid and 1-methyl-2-pyrrolecarboxylic acid.
    The journal of physical chemistry. A, 2009, Sep-03, Volume: 113, Issue:35

    Topics: Calorimetry; Carboxylic Acids; Computer Simulation; Gases; Models, Molecular; Molecular Conformation; Phase Transition; Proline; Pyrroles; Thermodynamics

2009
Enantiomerically pure polyheterocyclic spiro-beta-lactams from trans-4-hydroxy-L-proline.
    The Journal of organic chemistry, 2010, Mar-19, Volume: 75, Issue:6

    Topics: Anti-Bacterial Agents; beta-Lactams; Heterocyclic Compounds; Hydroxylation; Molecular Structure; Proline; Pyrroles; Spiro Compounds; Stereoisomerism

2010
L-Proline nutrition and catabolism in Staphylococcus saprophyticus.
    Antonie van Leeuwenhoek, 2011, Volume: 99, Issue:4

    Topics: Arginine; Cell Membrane; Culture Media; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases; Staphylococcus saprophyticus

2011
Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:3

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Collagen; delta-1-Pyrroline-5-Carboxylate Reductase; DNA Mutational Analysis; Elastin; Family; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Middle Aged; Models, Biological; Mutation, Missense; Phenotype; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Young Adult

2011
A straightforward route to enantiopure 2-substituted-3,4-dehydro-β-proline via ring closing metathesis.
    Amino acids, 2011, Volume: 41, Issue:3

    Topics: Amination; Amino Acids, Cyclic; Carbonates; Esters; Iridium; Peptidomimetics; Proline; Pyrroles; Stereoisomerism

2011
Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.
    Biochemistry, 2011, Jul-12, Volume: 50, Issue:27

    Topics: Actinomycetales; Antifungal Agents; Depsipeptides; Halogenation; Indoles; Isoleucine; Multigene Family; Piperazine; Piperazines; Proline; Pyrroles; Soil Microbiology; Sulfhydryl Compounds; Tryptophan

2011
Elevation of free proline and proline-rich protein levels by simultaneous manipulations of proline biosynthesis and degradation in plants.
    Plant science : an international journal of experimental plant biology, 2011, Volume: 181, Issue:2

    Topics: Arabidopsis; Bacterial Proteins; Cell Wall; Chloroplasts; Cytosol; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Medicago sativa; Mutation; Nicotiana; Phosphotransferases (Carboxyl Group Acceptor); Plant Proteins; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; RNA, Antisense; RNA, Plant; Salinity; Stress, Physiological

2011
Production of anticancer polyenes through precursor-directed biosynthesis.
    Organic & biomolecular chemistry, 2011, Sep-21, Volume: 9, Issue:18

    Topics: Antineoplastic Agents; Fungi; HeLa Cells; Humans; Inhibitory Concentration 50; Neoplasms; Polyenes; Proline; Pyrones; Pyrroles

2011
New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis.
    Chembiochem : a European journal of chemical biology, 2011, Oct-17, Volume: 12, Issue:15

    Topics: Alkaloids; Animals; Axinella; Imidazoles; Lysine; Metabolic Networks and Pathways; Proline; Pyrroles

2011
Biosynthesis of the nargenicin A1 pyrrole moiety from Nocardia sp. CS682.
    Applied microbiology and biotechnology, 2012, Volume: 93, Issue:2

    Topics: Acyl-CoA Dehydrogenase; Adenosine Triphosphate; Biosynthetic Pathways; Carrier Proteins; Cloning, Molecular; Genes, Bacterial; Lactones; Nocardia; Proline; Pyrroles; Transferases

2012
Labelless impedance immunosensor based on polypyrrole-pyrolecarboxylic acid copolymer for hCG detection.
    Talanta, 2011, Oct-15, Volume: 85, Issue:5

    Topics: Antigens; Biosensing Techniques; Chorionic Gonadotropin; Limit of Detection; Proline; Pyrroles

2011
Total syntheses of (-)-hanishin, (-)-longamide B, and (-)-longamide B methyl ester via a novel preparation of N-substituted pyrrole-2-carboxylates [corrected].
    Organic letters, 2012, Feb-17, Volume: 14, Issue:4

    Topics: Esters; Hydrogenation; Methylation; Molecular Structure; Proline; Pyrroles

2012
Ornithine-delta-aminotransferase and proline dehydrogenase genes play a role in non-host disease resistance by regulating pyrroline-5-carboxylate metabolism-induced hypersensitive response.
    Plant, cell & environment, 2012, Volume: 35, Issue:7

    Topics: Arabidopsis; Disease Resistance; Gene Expression Regulation, Plant; Gene Silencing; Mitochondria; Nicotiana; Ornithine-Oxo-Acid Transaminase; Plant Proteins; Proline; Proline Oxidase; Pseudomonas syringae; Pyrroles; Reactive Oxygen Species

2012
Molecular structure, spectral studies, intra and intermolecular interactions analyses in a novel ethyl 4-[3-(2-chloro-phenyl)-acryloyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate and its dimer: A combined DFT and AIM approach.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 94

    Topics: Dimerization; Electrons; Entropy; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Proline; Pyrroles; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Vibration

2012
A network perspective on metabolic inconsistency.
    BMC systems biology, 2012, May-14, Volume: 6

    Topics: Adenoma; Adipates; Adrenal Glands; Aldosterone; Humans; Metabolic Networks and Pathways; Proline; Pyrroles; Systems Biology; Transcriptome

2012
A study of proline metabolism in canola (Brassica napus L.) seedlings under salt stress.
    Molecules (Basel, Switzerland), 2012, May-16, Volume: 17, Issue:5

    Topics: Brassica napus; Gene Expression Regulation, Plant; Phosphotransferases (Alcohol Group Acceptor); Plant Roots; Plant Shoots; Proline; Proline Oxidase; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Salt Tolerance; Seedlings; Sodium Chloride

2012
The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast.
    FEBS letters, 2012, Jul-30, Volume: 586, Issue:16

    Topics: Anions; Cell Death; Dose-Response Relationship, Drug; Gene Expression Regulation, Fungal; Mitochondria; Models, Biological; Oxidative Stress; Oxygen Consumption; Proline; Pyrroles; Reactive Oxygen Species; Saccharomyces cerevisiae; Superoxides; Time Factors

2012
Synthesis of 4-hydroxy-β3-homoprolines and their insertion in α/β/α-tripeptides.
    Amino acids, 2013, Volume: 44, Issue:2

    Topics: Molecular Structure; Oligopeptides; Proline; Pyrroles; Stereoisomerism

2013
The synthesis of low molecular weight pyrrolo[2,3-c]pyridine-7-one scaffold.
    Molecular diversity, 2012, Volume: 16, Issue:4

    Topics: Alkylation; Cyclization; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Proline; Pyridines; Pyridones; Pyrroles

2012
A novel Δ(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation.
    Journal of plant physiology, 2013, Feb-15, Volume: 170, Issue:3

    Topics: Gene Expression Regulation, Plant; Medicago truncatula; Nitrogen; Nitrogen Fixation; Ornithine-Oxo-Acid Transaminase; Plant Growth Regulators; Proline; Pyrroles; Stress, Physiological; Symbiosis

2013
Spiroheterocyclization of methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates by the action of 3-(arylamino)-1H-inden-1-ones.
    Molecules (Basel, Switzerland), 2012, Nov-22, Volume: 17, Issue:12

    Topics: Cinnamates; Indenes; Molecular Structure; Proline; Pyrroles; Structure-Activity Relationship

2012
Role of the putative osmosensor Arabidopsis histidine kinase1 in dehydration avoidance and low-water-potential response.
    Plant physiology, 2013, Volume: 161, Issue:2

    Topics: Abscisic Acid; Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Blotting, Western; Dehydration; Dioxygenases; Gene Expression Regulation, Plant; Ligases; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; Mutation; Osmolar Concentration; Plant Stomata; Plant Transpiration; Proline; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Water; Water-Electrolyte Balance

2013
Pharmacokinetic evaluation of the interaction between hepatitis C virus protease inhibitor boceprevir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and pravastatin.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6

    Topics: Adolescent; Adult; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Interactions; Female; Hepacivirus; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pravastatin; Proline; Protease Inhibitors; Pyrroles; Treatment Outcome; Young Adult

2013
Study to elucidate formation pathways of selected roast-smelling odorants upon extrusion cooking.
    Journal of agricultural and food chemistry, 2013, Oct-30, Volume: 61, Issue:43

    Topics: Cooking; Flavoring Agents; Glucose; Maillard Reaction; Odorants; Oryza; Proline; Pyrroles

2013
Sensomics analysis of key hazelnut odorants (Corylus avellana L. 'Tonda Gentile') using comprehensive two-dimensional gas chromatography in combination with time-of-flight mass spectrometry (GC×GC-TOF-MS).
    Journal of agricultural and food chemistry, 2013, Jun-05, Volume: 61, Issue:22

    Topics: Acetylation; Carbon Isotopes; Corylus; Distillation; Food Handling; Food Inspection; Food Quality; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Italy; Limit of Detection; Nuts; Odorants; Olfactometry; Proline; Pyrroles; Pyrrolidines; Sensation; Volatile Organic Compounds

2013
Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.
    Environmental microbiology, 2014, Volume: 16, Issue:3

    Topics: Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Base Sequence; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutation; Proline; Promoter Regions, Genetic; Pyrroles; Sequence Alignment; Trans-Activators

2014
Effect of drought and combined drought and heat stress on polyamine metabolism in proline-over-producing tobacco plants.
    Plant physiology and biochemistry : PPB, 2013, Volume: 73

    Topics: Adaptation, Physiological; Arabidopsis Proteins; Droughts; Genes, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Malondialdehyde; Multienzyme Complexes; Nicotiana; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Phosphotransferases (Alcohol Group Acceptor); Plant Leaves; Plant Proteins; Plant Roots; Polyamine Oxidase; Polyamines; Proline; Putrescine; Pyrroles; Spermidine; Spermine; Transformation, Genetic; Water

2013
Synthetically useful noncatalytic strategy: a stereocontrolled rapid cyclization of a three component system to afford hexahydropyrrolizines.
    Chemical communications (Cambridge, England), 2013, Nov-04, Volume: 49, Issue:85

    Topics: Aldehydes; Catalysis; Cyclization; Esters; Hydrolysis; Molecular Structure; Proline; Pyrroles; Stereoisomerism; Time Factors

2013
Context of action of proline dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis.
    BMC plant biology, 2014, Jan-13, Volume: 14

    Topics: Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species

2014
Asymmetric domino aza-Michael addition/[3 + 2] cycloaddition reactions as a versatile approach to α,β,γ-triamino acid derivatives.
    Organic letters, 2014, Feb-21, Volume: 16, Issue:4

    Topics: Amino Acids; Cycloaddition Reaction; Molecular Structure; Peptides; Proline; Pyrazoles; Pyrroles; Stereoisomerism

2014
Metal-free, one-pot conversion of proline derivatives into 2-aryl-3-iodo pyrrolidines by a sequential scission-iodination-arylation process.
    Organic & biomolecular chemistry, 2014, Dec-21, Volume: 12, Issue:47

    Topics: Catalysis; Decarboxylation; Halogenation; Oxidation-Reduction; Proline; Pyrroles; Pyrrolidines; Stereoisomerism

2014
Microwave-promoted, metal- and catalyst-free decarboxylative α,β-difunctionlization of secondary α-amino acids via pseudo-four-component reactions.
    Organic letters, 2014, Nov-07, Volume: 16, Issue:21

    Topics: Aldehydes; Catalysis; Imino Acids; Ketones; Metals; Microwaves; Molecular Structure; Proline; Pyrroles; Stereoisomerism

2014
One-pot synthesis of pyrrole-2-carboxylates and -carboxamides via an electrocyclization/oxidation sequence.
    The Journal of organic chemistry, 2014, Dec-05, Volume: 79, Issue:23

    Topics: Catalysis; Copper; Cyclization; Electrochemistry; Esters; Oxidation-Reduction; Proline; Pyrroles; Stereoisomerism

2014
Exogenous proline application ameliorates toxic effects of arsenate in Solanum melongena L. seedlings.
    Ecotoxicology and environmental safety, 2015, Volume: 117

    Topics: Antioxidants; Arsenates; Catalase; Chlorophyll; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Photosynthesis; Photosystem II Protein Complex; Proline; Pyrroles; Reactive Oxygen Species; Seedlings; Solanum melongena; Superoxide Dismutase

2015
An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.
    PLoS pathogens, 2015, Volume: 11, Issue:5

    Topics: Biological Transport; Cell Proliferation; Drug Resistance, Multiple; Energy Metabolism; Gene Expression Regulation; Gene Knockout Techniques; Membrane Potential, Mitochondrial; Metabolomics; Mitochondria; Mitochondrial Membrane Transport Proteins; Parasitic Sensitivity Tests; Pentamidine; Proline; Protein Structure, Tertiary; Protozoan Proteins; Pyrroles; Recombinant Proteins; RNA Interference; Trypanocidal Agents; Trypanosoma brucei brucei

2015
Grassland species differentially regulate proline concentrations under future climate conditions: an integrated biochemical and modelling approach.
    The New phytologist, 2015, Volume: 208, Issue:2

    Topics: Climate; Glutamic Acid; Grassland; Metabolic Networks and Pathways; Models, Biological; Monte Carlo Method; Ornithine; Proline; Pyrroles; RNA, Messenger; Species Specificity; Thermodynamics

2015
2-Acetyl-1-pyrroline augmentation in scented indica rice (Oryza sativa L.) varieties through Δ(1)-pyrroline-5-carboxylate synthetase (P5CS) gene transformation.
    Applied biochemistry and biotechnology, 2015, Volume: 177, Issue:7

    Topics: Agrobacterium; Genetic Engineering; Odorants; Oryza; Phosphotransferases (Alcohol Group Acceptor); Proline; Pyrroles; Regeneration; Seeds; Transformation, Genetic; Volatile Organic Compounds

2015
Interaction of Mg with heavy metals (Cu, Cd) in T. aestivum with special reference to oxidative and proline metabolism.
    Journal of plant research, 2016, Volume: 129, Issue:3

    Topics: Ascorbate Peroxidases; Carotenoids; Catalase; Chlorophyll; Chlorophyll A; Hydrogen Peroxide; Magnesium; Malondialdehyde; Metals, Heavy; Oxidation-Reduction; Plant Roots; Plant Shoots; Proline; Pyrroles; Superoxide Dismutase; Triticum

2016
Submicron magnetic core conducting polypyrrole polymer shell: Preparation and characterization.
    Materials science & engineering. C, Materials for biological applications, 2016, Apr-01, Volume: 61

    Topics: Electrochemical Techniques; Magnetics; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polymers; Proline; Pyrroles; Spectroscopy, Fourier Transform Infrared; Surface Properties

2016
Supplementation of 2-Ap, Zn and La Improves 2-Acetyl-1-Pyrroline Concentrations in Detached Aromatic Rice Panicles In Vitro.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Culture Media; Inflorescence; Lanthanum; Oryza; Proline; Proline Oxidase; Pyrroles; Seeds; Tissue Culture Techniques; Zinc

2016
Manganese-induced regulations in growth, yield formation, quality characters, rice aroma and enzyme involved in 2-acetyl-1-pyrroline biosynthesis in fragrant rice.
    Plant physiology and biochemistry : PPB, 2016, Volume: 103

    Topics: Gene Expression Regulation, Plant; Manganese; Ornithine-Oxo-Acid Transaminase; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles; Seeds

2016
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA.
    Bioscience reports, 2016, Volume: 36, Issue:6

    Topics: Bacterial Proteins; Chimera; DNA-Binding Proteins; Escherichia coli; Membrane Proteins; Proline; Proline Oxidase; Protein Binding; Protein Domains; Pyrroles; Rhodobacter capsulatus

2016
Total Synthesis and Stereochemical Revision of the 2-Formylpyrrole Alkaloid Hemerocallisamine I.
    Journal of natural products, 2017, 06-23, Volume: 80, Issue:6

    Topics: Alkaloids; Liliaceae; Molecular Structure; Proline; Pyrroles; Stereoisomerism

2017
Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation.
    Plant physiology, 2017, Volume: 175, Issue:1

    Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Binding Sites; Glutamate-5-Semialdehyde Dehydrogenase; Multienzyme Complexes; Mutation; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Plant Growth Regulators; Proline; Promoter Regions, Genetic; Pyrroles; Signal Transduction; Transcription Factors; Transcriptional Activation

2017
Identification of Δ
    Plant signaling & behavior, 2017, Nov-02, Volume: 12, Issue:11

    Topics: Gene Expression Regulation, Plant; Lotus; Ornithine-Oxo-Acid Transaminase; Osmotic Pressure; Proline; Pyrroles; Stress, Physiological

2017
Remote C-H Hydroxylation by an α-Ketoglutarate-Dependent Dioxygenase Enables Efficient Chemoenzymatic Synthesis of Manzacidin C and Proline Analogs.
    Journal of the American Chemical Society, 2018, 01-24, Volume: 140, Issue:3

    Topics: AlkB Enzymes; Biocatalysis; Escherichia coli; Hydroxylation; Ketoglutaric Acids; Models, Molecular; Proline; Pyrimidines; Pyrroles; Streptomyces; Substrate Specificity

2018
An Ancestral Allele of
    Plant physiology, 2018, Volume: 178, Issue:2

    Topics: Adaptation, Physiological; Alleles; Arabidopsis; Chromosome Mapping; Chromosomes, Plant; Droughts; Hordeum; Plant Roots; Proline; Pyrroles; Quantitative Trait Loci; Water

2018
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea

2019
Synthesis of di- and trihydroxy proline derivatives from D-glycals: Application in the synthesis of polysubstituted pyrrolizidines and bioactive 1C-aryl/alkyl pyrrolidines.
    Carbohydrate research, 2019, Mar-01, Volume: 475

    Topics: Deoxyglucose; Molecular Structure; Proline; Pyrroles

2019
Different tillage induces regulation in 2-acetyl-1-pyrroline biosynthesis in direct-seeded fragrant rice.
    BMC plant biology, 2019, Jul-12, Volume: 19, Issue:1

    Topics: Odorants; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles; Seeds

2019
Foliar application of sodium selenate induces regulation in yield formation, grain quality characters and 2-acetyl-1-pyrroline biosynthesis in fragrant rice.
    BMC plant biology, 2019, Nov-15, Volume: 19, Issue:1

    Topics: Antioxidants; Biomass; Catalase; Edible Grain; Gene Expression Regulation, Plant; Malondialdehyde; Oryza; Peroxidases; Plant Proteins; Proline; Pyrroles; Selenic Acid; Superoxide Dismutase

2019
Characterization and expression analysis of P5CS (Δ1-pyrroline-5-carboxylate synthase) gene in two distinct populations of the Atlantic Forest native species Eugenia uniflora L.
    Molecular biology reports, 2020, Volume: 47, Issue:2

    Topics: Aldehyde Dehydrogenase; Droughts; Eugenia; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Ligases; Multienzyme Complexes; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Plants; Proline; Pyrroles; Stress, Physiological

2020
Different Reaction Specificities of F
    Journal of the American Chemical Society, 2020, 02-19, Volume: 142, Issue:7

    Topics: Benzodiazepines; Catalysis; Depsipeptides; Lincomycin; Models, Molecular; Oxidoreductases; Peptides, Cyclic; Proline; Pyrroles; Riboflavin; Substrate Specificity; Tyrosine

2020
Selenium-silicon (Se-Si) induced modulations in physio-biochemical responses, grain yield, quality, aroma formation and lodging in fragrant rice.
    Ecotoxicology and environmental safety, 2020, Jun-15, Volume: 196

    Topics: Antioxidants; Dose-Response Relationship, Drug; Edible Grain; Malondialdehyde; Odorants; Oryza; Proline; Pyrroles; Selenium; Silicon; Soil

2020
Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools.
    The Biochemical journal, 2020, 05-29, Volume: 477, Issue:10

    Topics: Cytosol; Electron Transport; Glutamic Acid; Mitochondria; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Trypanosoma cruzi

2020
Structure of Thermococcus litoralis Δ
    Acta crystallographica. Section D, Structural biology, 2020, May-01, Volume: 76, Issue:Pt 5

    Topics: Archaeal Proteins; NAD; Proline; Protein Binding; Protein Conformation; Pyrroles; Pyrroline Carboxylate Reductases; Thermococcus

2020
Facile Synthesis of NH-Free 5-(Hetero)Aryl-Pyrrole-2-Carboxylates by Catalytic C-H Borylation and Suzuki Coupling.
    Molecules (Basel, Switzerland), 2020, Apr-30, Volume: 25, Issue:9

    Topics: Catalysis; Chemistry Techniques, Synthetic; Cyclization; Molecular Structure; Oxidative Coupling; Proline; Pyrroles

2020
Match-mismatch effects in two-fold transfer of chirality within a Möbius metallo-receptor.
    Chemical communications (Cambridge, England), 2020, Aug-11, Volume: 56, Issue:64

    Topics: Chelating Agents; Ligands; Macrocyclic Compounds; Molecular Conformation; Phenethylamines; Proline; Pyrroles; Stereoisomerism

2020
Exogenous proline induces regulation in 2-acetyl-1-pyrroline (2-AP) biosynthesis and quality characters in fragrant rice (Oryza sativa L.).
    Scientific reports, 2020, 08-18, Volume: 10, Issue:1

    Topics: China; Edible Grain; Gene Expression Regulation, Plant; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles

2020
Molybdenum improves 2-acetyl-1-pyrroline, grain quality traits and yield attributes in fragrant rice through efficient nitrogen assimilation under cadmium toxicity.
    Ecotoxicology and environmental safety, 2021, Mar-15, Volume: 211

    Topics: Cadmium; Edible Grain; Molybdenum; Nitrate Reductase; Nitrogen; Odorants; Oryza; Perfume; Photosynthesis; Plant Proteins; Proline; Pyrroles

2021
Lanthanum (La) improves growth, yield formation and 2-acetyl-1-pyrroline biosynthesis in aromatic rice (Oryza sativa L.).
    BMC plant biology, 2021, May-25, Volume: 21, Issue:1

    Topics: Antioxidants; Chlorophyll; Edible Grain; Lanthanum; Oryza; Photosynthesis; Plant Proteins; Proline; Proline Oxidase; Pyrroles; Seeds

2021
Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Binding Sites; Cysteine; Humans; Kinetics; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Thiazolidines

2021
Resolving the Hydride Transfer Pathway in Oxidative Conversion of Proline to Pyrrole.
    Biochemistry, 2022, 02-01, Volume: 61, Issue:3

    Topics: Biocatalysis; Bone Morphogenetic Protein 3; Carrier Proteins; Catalytic Domain; Flavins; Hydrogen Bonding; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction; Oxidoreductases; Proline; Protein Conformation; Pyrroles; Quantum Theory

2022
Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars.
    Scientific reports, 2022, 03-10, Volume: 12, Issue:1

    Topics: Amino Acids; gamma-Aminobutyric Acid; Ornithine; Oryza; Proline; Putrescine; Pyrroles; Pyruvaldehyde; Salt Stress

2022
Foliar application of procyanidins enhanced the biosynthesis of 2-acetyl-1-pyrroline in aromatic rice (Oryza sativa L.).
    BMC plant biology, 2022, Jul-29, Volume: 22, Issue:1

    Topics: gamma-Aminobutyric Acid; Odorants; Oryza; Proanthocyanidins; Proline; Pyrroles

2022
Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by
    ACS chemical biology, 2022, 09-16, Volume: 17, Issue:9

    Topics: Anti-Bacterial Agents; Biological Products; Carbon; Mixed Function Oxygenases; Multigene Family; Proline; Pyrroles; Serine; Streptomyces

2022
Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II.
    Communications biology, 2022, 09-21, Volume: 5, Issue:1

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Biomarkers; Phosphates; Proline; Proline Oxidase; Pyridoxal; Pyrroles

2022