Page last updated: 2024-08-18

pyrroles and lysine

pyrroles has been researched along with lysine in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199013 (11.40)18.7374
1990's19 (16.67)18.2507
2000's41 (35.96)29.6817
2010's34 (29.82)24.3611
2020's7 (6.14)2.80

Authors

AuthorsStudies
Batlle, AM; Stella, AM1
Barnsley, PG; Boyle, SM; Sells, BH1
DeCaprio, AP; O'Neill, EA1
Smith, IC1
Barratt, MD; Chapman, D; Dodd, GH1
Baxter, CS; Byvoet, P1
Grunberger, D; Reich, E; Ward, DC1
Peraino, C1
Austic, RE; Nesheim, MC1
Belcher, RV; Lockwood, WH; Rimington, C1
Holbrook, JJ; Jeckel, R1
Anthony, DC; Boekelheide, K; Graham, DG; Maschmann, NA; Richards, RG; Shaw, BR; Wolfram, JW1
Monnier, VM; Nagaraj, RH1
Hidalgo, FJ; Zamora, R1
Miyata, S; Monnier, VM; Perry, G; Richey, PL; Sayre, LM; Smith, MA; Stern, D; Taneda, S; Yan, SD1
Castellani, R; Perry, G; Richey, PL; Smith, MA1
Bailey, AJ; Paul, RG1
Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV1
Horie, K; Iida, Y; Maeda, K; Miyata, T; Sugiyama, S; Tanaka, H; Tsuyuki, M1
DeCaprio, AP; Hauer, CR; Spink, DC; Zhu, M1
Castellani, RJ; Cohen, ML; Harris, PL; Monnier, VM; Perry, G; Smith, MA1
de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A1
Deyl, Z; Miksík, I1
Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL1
Block, C; Ferguson, K; Fogarty, J; Haas, C; Hampel, N; Ni, Z; Polak, J; Razmjouei, K; Seftel, AD; Vaziri, ND; Wang, RZ1
Angelini, G; Dagna-Bricarelli, F; Dapino, D; Garibaldi, S; Odetti, P; Perry, G; Piombo, G; Smith, M; Tabaton, M; Traverso, N; Zaccheo, D1
Boutaud, O; Brame, CJ; Oates, JA; Roberts, LJ; Salomon, RG1
Beck, W; Deppisch, R; Hänsch, GM; Henle, T; Hergesell, O; Ritz, E1
Kansal, MM; Liu, Y; Sayre, LM; Xu, G1
Sayre, LM; Xu, G2
Ames, JM; Hill, VM; Isaacs, NS; Ledward, DA1
Angelini, G; Garibaldi, S; Marinelli, L; Menini, S; Norese, R; Odetti, P; Perry, G; Siedlak, S; Smith, MA; Tabaton, M; Traverso, N; Valentini, S; Zaccheo, D1
Cattaneo, S; De Noni, I; Pellegrino, L1
Alaiz, M; Hidalgo, FJ; Zamora, R1
Cleveland, DW; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Liu, J; Nagai, R; Nakano, I; Nakashima, K; Ohama, E; Shibata, N; Takikawa, M1
Assmann, M; Hochgürtel, M; Köck, M; Lindel, T1
Brady, JD; Robins, SP1
Faist, V; Hofmann, T; Lindenmeier, M1
Costello, PJ; Henschke, PA1
Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M1
Hoff, HF; Hoppe, G; O'Neil, J; Salomon, RL; Wu, Z1
Itakura, K; Uchida, K1
Liu, J; Sayre, LM; Xu, G; Yuan, Q; Zhang, WH1
Daimon, M; Hirata, A; Igarashi, M; Kameda, W; Kato, T; Ohnuma, H; Oizumi, T; Saitoh, T; Sugiyama, K; Yamaguchi, H1
Beppu, M; Hata, I; Hiraoka, M; Kaji, M; Kawakami, H; Mayumi, M; Momoi, T; Sekine, K; Todoroki, Y; Tsukahara, H; Uchiyama, M; Yorifuji, T; Yoshihara, K1
ARIMURA, GK; YUNIS, AA1
Hiraoka, M; Ito, S; Mayumi, M; Noiri, E; Ohta, N; Sato, S; Shibata, R; Tsukahara, H1
Hofmann, T; Lindenmeier, M1
Aizawa, K; Hirano, K; Inakuma, T; Kiho, T; Usui, S1
Aso, Y; Inukai, T; Sekine, K; Takanashi, K; Takebayashi, K; Yoshida, N; Yoshihara, K1
Krzycki, JA1
Ahmed, N; Horiuchi, S; Jono, T; Lin, X; Nagai, R; Takeya, M; Thornalley, PJ1
Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W1
Baer, BR; Henne, KR; Rettie, AE1
Böhm, S; Bubenzer, C; Scheer, H; Wu, D; Zhang, L; Zhao, KH; Zhou, M1
Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T1
Erbersdobler, HF; Grothe, D; Hofmann, T; Lindenmeier, M; Somoza, V; Wenzel, E1
Grube, A; Köck, M; Lichte, E1
Anraku, M; Kitamura, K; Maruyama, T; Mera, K; Nakajou, K; Otagiri, M; Tomita, K1
Amano, S; Fukayama, M; Kaji, Y; Nagai, R; Oshika, T; Takazawa, Y1
Alves, CN; Andrés, J; Castillo, R; Martí, S; Moliner, V; Silla, E; Tuñón, I1
Dai, Z; Monnier, VM; Nemet, I; Shen, W1
Hidalgo, FJ; León, MM; Zamora, R1
Boonyarat, C; Grierson, DS; Kammasud, N; Saiki, I; Sakurai, H; Tsunoda, S; Vajragupta, O1
Aranganathan, S; Nalini, N; Panneer Selvam, J1
Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP1
Ahmad, W; Deng, Y; Li, L1
Aranganathan, S; Nalini, N; Panneerselvam, J1
Crabb, JW; Gu, J; Gu, X; Nagaraj, RH; Ni, J; Yuan, X; Yue, X1
Aranganathan, S; Gopalan, R; Nalini, N; Selvam, JP1
Brandsch, M; Geissler, S; Hellwig, M; Henle, T; Knütter, I; Peto, A1
Murata, M; Ono, H; Sakamoto, J; Takenaka, M1
Jakobs, C; Struys, EA1
Baur, J; Cosnier, S; Defrancq, E; Gondran, C; Holzinger, M; Perrot, H1
Murata, M; Nomi, Y; Ono, H; Sakamoto, J; Takenaka, M1
Brock, A; Cellitti, SE; Chiu, HP; Crossgrove, T; Fan, Q; Geierstanger, BH; Grünewald, J; Hao, X; Jones, DH; Lesley, SA; Okach, L; Ou, W; Patterson, P; Quinn, LL; Uno, T1
Ansorge, S; Bank, U; Biton, A; Brocke, S; Reinhold, D; Täger, M1
Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM1
Al Mourabit, A; Cachet, N; Genta-Jouve, G; Holderith, S; Jeffree, R; Oberhänsli, F; Teyssié, JL; Thomas, OP1
Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J1
Masuzaki, R; Murata, M; Nomi, Y; Ono, H; Otsuka, Y; Takenaka, M; Terasawa, N1
Heilmann, M; Ilchmann, A; Toda, M; Vieths, S1
Brimble, MA; Cooper, GJ; Woods, TM1
Cataldi, TR; Ciriello, R; Guerrieri, A1
Einsle, O; Gerhardt, S; Günther, S; Hügle, M; Jung, M; Lucas, X; Schmidtkunz, K; Schüle, R; Wohlwend, D1
Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH1
Bacher, A; Beck, P; Groll, M; Quitterer, F1
Chikazawa, M; Hagihara, Y; Hioki, Y; Maruyama, S; Matsumi, N; Miyashita, H; Nakashima, F; Otaki, N; Shibata, T; Shimozu, Y; Uchida, K1
Cataldi, TR; Ciriello, R; Crispo, F; Guerrieri, A1
Gao, H; Hua, H; Li, C; Lin, D; Peng, Y; Zheng, J1
Murata, M; Noda, K; Yamada, S1
Globisch, M; Henle, T; Kaden, D1
Bunzel, D; Franz, CM; Hellwig, M; Henle, T; Huch, M; Kulling, SE1
Déméné, H; Granier, S; Huang, W; Kobilka, BK; Laeremans, T; Manglik, A; Mas, C; Sounier, R; Steyaert, J1
Wang, K; Xing, Y; Yu, Q; Zhang, H1
Fu, Q; Li, B; Li, L; Liang, Z; Xu, Z; Zhang, X1
Amarnath, K; Amarnath, V1
Hellwig, M; Henle, T; Witte, S1
Bax, A; Levine, RL; Werner-Allen, JW1
Fu, L; Liebler, DC; Liu, K; Porter, NA; Sun, R; Tallman, KA; Tian, C; Yang, J; Yang, Y1
Li, H; Yu, SJ1
Asamitsu, S; Bando, T; Hashiya, K; Obata, S; Phan, AT; Sugiyama, H1
Albericio, F; de la Torre, BG; Govender, T; Gudimella, SK; Jad, YE1
Ciriello, R; De Gennaro, F; Frascaro, S; Guerrieri, A1
Chikazawa, M; Hioki, Y; Hirade, N; Hirose, S; Itakura, M; Kikuchi, R; Matsushita, T; Miyashita, H; Nagata, K; Shibata, T; Uchida, K; Yoshitake, J; Zhang, M1
Chen, X; Lai, Y; Lei, C; Liang, Z; Yang, Y; Yang, Z; Zeng, Y1
Cattaneo, S; De Noni, I; Mallardi, D; Masotti, F; Pica, V; Roggero, P; Stuknytė, M; Tabasso, C1
Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q1
Ha, J; Kim, M; Lee, J; Park, JS; Park, SH; Seo, D1
Cheng, T; Li, N; Li, W; Lin, G; Wang, H; Yang, X; Zhang, F; Zheng, J1
Banerjee, S1
Ciesielska, K; Muńko, M; Pluskota-Karwatka, D1
Ciesielska, K; Hoffmann, M; Muńko, M; Pluskota-Karwatka, D1

Reviews

7 review(s) available for pyrroles and lysine

ArticleYear
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
New biomarkers of Maillard reaction damage to proteins.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles

1996
Advanced glycation end-products in diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Animals; Arginine; Blood Glucose; Diabetic Nephropathies; Glycation End Products, Advanced; Glycosylation; Humans; Immunohistochemistry; Lysine; Norleucine; Proteins; Pyrroles

1996
Post-translational non-enzymatic modification of proteins. I. Chromatography of marker adducts with special emphasis to glycation reactions.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Oct-10, Volume: 699, Issue:1-2

    Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Glycosylation; Imidazoles; Lysine; Malondialdehyde; Mass Spectrometry; Norleucine; Protein Processing, Post-Translational; Proteins; Pyrroles

1997
Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases.
    Current opinion in chemical biology, 2004, Volume: 8, Issue:5

    Topics: Amides; Codon; Corrinoids; Dimethylamines; Imines; Lysine; Methane; Methylamines; Methyltransferases; Models, Molecular; Pyrroles

2004
The Maillard reaction and food allergies: is there a link?
    Clinical chemistry and laboratory medicine, 2014, Jan-01, Volume: 52, Issue:1

    Topics: Arginine; Dendritic Cells; Food Hypersensitivity; Glycation End Products, Advanced; Humans; Immunoglobulin E; Lysine; Maillard Reaction; Norleucine; Pyrroles; Receptors, Scavenger; T-Lymphocytes

2014
Review of pentosidine and pyrraline in food and chemical models: formation, potential risks and determination.
    Journal of the science of food and agriculture, 2018, Volume: 98, Issue:9

    Topics: Arginine; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Food Analysis; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Lysine; Molecular Structure; Norleucine; Pyrroles; Risk Factors; Uremia

2018

Trials

1 trial(s) available for pyrroles and lysine

ArticleYear
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde

2003

Other Studies

106 other study(ies) available for pyrroles and lysine

ArticleYear
Delta aminolaevulinate dehydratase: its mechanism of action.
    The International journal of biochemistry, 1978, Volume: 9, Issue:12

    Topics: Histidine; Lysine; Macromolecular Substances; Models, Biological; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Sulfhydryl Compounds

1978
Synthesis of messenger RNA coding for elongation factors G and Ts during nutritional shift-up in Escherichia coli K-12.
    Biochemical and biophysical research communications, 1976, Aug-09, Volume: 71, Issue:3

    Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Escherichia coli; Kinetics; Lysine; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Protein Biosynthesis; Pyrroles; Ribosomal Proteins; Ribosomes; RNA, Messenger; Transcription, Genetic; Tritium

1976
Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2,5-hexanedione exposure.
    Toxicology and applied pharmacology, 1985, Volume: 78, Issue:2

    Topics: Animals; Axons; Brain Stem; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Hexanones; In Vitro Techniques; Ketones; Lysine; Male; Pyrroles; Rats; Rats, Inbred Strains; Spinal Cord

1985
A study of the conformational properties of bovine pancreatic ribonuclease A by electron paramagnetic resonance.
    Biochemistry, 1968, Volume: 7, Issue:2

    Topics: Animals; Binding Sites; Bromine; Cattle; Chemical Phenomena; Chemistry, Physical; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Imides; Lysine; Methods; Pancreas; Pyrroles; Ribonucleases; Temperature

1968
A spin label for tyrosine residues.
    Biochimica et biophysica acta, 1969, Dec-23, Volume: 194, Issue:2

    Topics: Chemical Phenomena; Chemistry; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Imidazoles; Lysine; Peptides; Pyrroles; Tyrosine

1969
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
    Cancer research, 1974, Volume: 34, Issue:6

    Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine

1974
7-Deazanebularin. Coding properties of triplets and polynucleotides.
    The Journal of biological chemistry, 1972, Feb-10, Volume: 247, Issue:3

    Topics: Adenine; Adenine Nucleotides; Amino Acids; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Genetic Code; Lysine; Nucleosides; Peptide Biosynthesis; Polynucleotides; Pyrimidines; Pyrroles; Ribonucleotides; Ribosomes; RNA, Transfer; Tritium

1972
Functional properties of ornithine-ketoacid aminotransferase from rat liver.
    Biochimica et biophysica acta, 1972, Nov-10, Volume: 289, Issue:1

    Topics: Animals; Apoproteins; Binding Sites; Buffers; Carbon Isotopes; Carboxylic Acids; Catalysis; Drug Stability; Glutamates; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Liver; Lysine; Ornithine; Phosphates; Pyridoxal Phosphate; Pyridoxamine; Pyrroles; Rats; Time Factors; Transaminases; Tromethamine

1972
Arginine, ornithine and proline metabolism of chicks: influence of diet and heredity.
    The Journal of nutrition, 1971, Volume: 101, Issue:10

    Topics: Amino Acid Oxidoreductases; Amino Acids; Aminoisobutyric Acids; Animals; Arginase; Arginine; Chickens; Depression, Chemical; Diet; Glutamates; Histidine; Kidney; Liver; Lysine; Organ Specificity; Ornithine; Oxidoreductases; Proline; Pyrroles; Selection, Genetic; Species Specificity; Stimulation, Chemical; Threonine; Transaminases; Tyrosine

1971
The excretion of porphyrin-peptide conjugates in porphyria variegata.
    Clinical science, 1968, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Aged; Bilirubin; Child; Child, Preschool; Chromatography, Paper; Cysteine; Feces; Female; Hematoporphyrins; Humans; Infant; Lysine; Male; Middle Aged; Peptides; Phenylalanine; Porphyrias; Porphyrins; Pyrroles

1968
A peptide containing a reactive lysyl group from ox liver glutamate dehydrogenase.
    The Biochemical journal, 1969, Volume: 111, Issue:5

    Topics: Amino Acid Sequence; Animals; Cattle; Chymotrypsin; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Lysine; Peptides; Pyrroles; Sulfur Isotopes; Trypsin

1969
Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking.
    Toxicology and applied pharmacology, 1982, Volume: 64, Issue:3

    Topics: Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanes; Hexanones; Lysine; Nervous System Diseases; Pyrroles

1982
Protein modification by the degradation products of ascorbate: formation of a novel pyrrole from the Maillard reaction of L-threose with proteins.
    Biochimica et biophysica acta, 1995, Nov-15, Volume: 1253, Issue:1

    Topics: Aminocaproates; Arginine; Blood Proteins; Caproates; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Fluorescence; Glycation End Products, Advanced; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Models, Chemical; Proteins; Pyrroles; Ribonuclease, Pancreatic; Spectrophotometry; Tetroses

1995
Linoleic acid oxidation in the presence of amino compounds produces pyrroles by carbonyl amine reactions.
    Biochimica et biophysica acta, 1995, Oct-05, Volume: 1258, Issue:3

    Topics: Aldehydes; Butylamines; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Epoxy Compounds; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Lipoxygenase; Lysine; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Pyrroles; Spectrometry, Fluorescence

1995
Advanced Maillard reaction end products are associated with Alzheimer disease pathology.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jun-07, Volume: 91, Issue:12

    Topics: Alzheimer Disease; Arginine; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Lysine; Maillard Reaction; Neurofibrillary Tangles; Norleucine; Pyrroles

1994
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
    Brain research, 1996, Oct-21, Volume: 737, Issue:1-2

    Topics: Aged; Aged, 80 and over; Arginine; Cerebral Cortex; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Heme Oxygenase (Decyclizing); Humans; Immunohistochemistry; Locus Coeruleus; Lysine; Microscopy, Immunoelectron; Middle Aged; Neurons; Norleucine; Oxidative Stress; Parkinson Disease; Pyrroles; Substantia Nigra

1996
Characterization of glutathione conjugates of pyrrolylated amino acids and peptides by liquid chromatography-mass spectrometry and tandem mass spectrometry with electrospray ionization.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Jan-24, Volume: 688, Issue:2

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrochemistry; Glutathione; Hexanones; Lysine; Mass Spectrometry; Oligopeptides; Oxidation-Reduction; Pyrroles

1997
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease.
    Neuroscience letters, 1997, Aug-08, Volume: 231, Issue:2

    Topics: Adolescent; Arginine; Astrocytes; Brain Diseases; Child; Cross-Linking Reagents; Crystallins; Demyelinating Diseases; Glycation End Products, Advanced; Humans; Inclusion Bodies; Lysine; Norleucine; Pyrroles

1997
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
    The Biochemical journal, 1997, Oct-01, Volume: 327 ( Pt 1)

    Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases

1997
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
    The Journal of clinical investigation, 1997, Dec-15, Volume: 100, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits

1997
Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS.
    Urology, 1997, Volume: 50, Issue:6

    Topics: Adult; Aged; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Electron Probe Microanalysis; Endothelium; Enzyme Induction; Erectile Dysfunction; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norleucine; Penis; Pyrroles

1997
Early glycoxidation damage in brains from Down's syndrome.
    Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3

    Topics: Aldehydes; Amyloid beta-Protein Precursor; Arginine; Brain; Cerebral Cortex; Down Syndrome; Gestational Age; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lysine; Norleucine; Oxidation-Reduction; Oxidative Stress; Pyrroles; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

1998
Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway.
    Biochemistry, 1999, Jul-20, Volume: 38, Issue:29

    Topics: Chromatography, Liquid; Cross-Linking Reagents; Lysine; Mass Spectrometry; Oligopeptides; Prostaglandin H2; Prostaglandins E; Prostaglandins H; Pyrroles; Schiff Bases; Time Factors

1999
Advanced glycated end-products (AGE) during haemodialysis treatment: discrepant results with different methodologies reflecting the heterogeneity of AGE compounds.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:8

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Female; Fluorescence; Glycation End Products, Advanced; Hemofiltration; Humans; Lysine; Male; Middle Aged; Molecular Weight; Norleucine; Pyrroles; Renal Dialysis

1999
Rapid cross-linking of proteins by 4-ketoaldehydes and 4-hydroxy-2-alkenals does not arise from the lysine-derived monoalkylpyrroles.
    Chemical research in toxicology, 1999, Volume: 12, Issue:9

    Topics: Aldehydes; Animals; Cattle; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanones; Lysine; Proteins; Pyrroles; Ribonuclease, Pancreatic; Schiff Bases; Serum Albumin, Bovine

1999
Structural elucidation of a 2:2 4-ketoaldehyde-amine adduct as a model for lysine-directed cross-linking of proteins by 4-ketoaldehydes.
    Chemical research in toxicology, 1999, Volume: 12, Issue:9

    Topics: Aldehydes; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; Lysine; Methylamines; Models, Chemical; Molecular Conformation; Molecular Structure; Pyrroles; Schiff Bases

1999
Effect of high hydrostatic pressure on the volatile components of a glucose-lysine model system.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:9

    Topics: Furans; Glucose; Hydrostatic Pressure; Ketones; Lysine; Models, Chemical; Pyrans; Pyrazines; Pyridines; Pyrroles; Volatilization

1999
Lipoperoxidation is selectively involved in progressive supranuclear palsy.
    Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:5

    Topics: Aged; Aldehydes; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxides; Lysine; Mesencephalon; Middle Aged; Norleucine; Pyrroles; Reference Values; Supranuclear Palsy, Progressive; tau Proteins; Thiobarbituric Acid Reactive Substances

2000
Formation of protein bound lysine-derived galactosyl and glucosyl pyrroles in heated model systems.
    Die Nahrung, 2000, Volume: 44, Issue:3

    Topics: Caseins; Chromatography, High Pressure Liquid; Dietary Carbohydrates; Food Analysis; Galactose; Glucose; Hot Temperature; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Protein Binding; Pyrroles; Reference Standards

2000
Contribution of pyrrole formation and polymerization to the nonenzymatic browning produced by amino-carbonyl reactions.
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:8

    Topics: alpha-Linolenic Acid; Amines; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Polymers; Pyrroles

2000
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Animals; Arginine; Female; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Immunoelectron; Middle Aged; Mutation; Norleucine; Pyrroles; Superoxide Dismutase; Superoxide Dismutase-1

2000
Synthesis of the marine natural product nalpha-(4-bromopyrrolyl-2-carbonyl)-L-homoarginine, a putative biogenetic precursor of the pyrrole-imidazole alkaloids.
    Journal of natural products, 2000, Volume: 63, Issue:11

    Topics: Alkaloids; Animals; Homoarginine; Hydroxylation; Imidazoles; Lysine; Magnetic Resonance Spectroscopy; Porifera; Pyrroles; Spectrometry, Mass, Fast Atom Bombardment

2000
Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: Avidin; Benzaldehydes; Binding Sites; Binding, Competitive; Biotinylation; Carboxylic Acids; Cathepsin K; Cathepsins; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Indicators and Reagents; Lysine; Mass Spectrometry; Models, Chemical; Papain; Peptides; Pyrroles; Trypsin

2001
Cross-linking of proteins by 3-(trifluoromethyl)-2,5-hexanedione. Model studies implicate an unexpected amine-dependent defluorinative substitution pathway competing with pyrrole formation.
    The Journal of organic chemistry, 2002, May-03, Volume: 67, Issue:9

    Topics: Cross-Linking Reagents; Hexanones; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Neurotoxins; Proteins; Pyrroles; Ribonucleases

2002
Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modulating activity.
    Journal of agricultural and food chemistry, 2002, Nov-20, Volume: 50, Issue:24

    Topics: Antioxidants; Bread; Caco-2 Cells; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Malondialdehyde; NADPH-Ferrihemoprotein Reductase; Polymers; Proteins; Pyrroles

2002
Mousy off-flavor of wine: precursors and biosynthesis of the causative N-heterocycles 2-ethyltetrahydropyridine, 2-acetyltetrahydropyridine, and 2-acetyl-1-pyrroline by Lactobacillus hilgardii DSM 20176.
    Journal of agricultural and food chemistry, 2002, Nov-20, Volume: 50, Issue:24

    Topics: Acetaldehyde; Acylation; Cations, Divalent; Deuterium; Ethanol; Fructose; Heterocyclic Compounds; Lactobacillus; Lysine; Metals; Ornithine; Pyridines; Pyrroles; Taste; Wine

2002
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Feb-01, Volume: 23, Issue:2

    Topics: Acetylcysteine; Aldehydes; Animals; Arteriosclerosis; Biological Transport; Cathepsin B; Cholesterol Esters; Chromatography, Liquid; Humans; Intracellular Membranes; Lipoproteins, LDL; Lysine; Lysosomes; Macrophages, Peritoneal; Mice; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Pyrroles; Spectrometry, Mass, Electrospray Ionization

2003
Lysine-derived fluorophores formed by autoxidation of linoleic acid.
    Chemistry and physics of lipids, 2003, Volume: 123, Issue:2

    Topics: Ascorbic Acid; Catalysis; Chromatography, High Pressure Liquid; Edetic Acid; Ferric Compounds; Fluoresceins; Imines; Linoleic Acid; Lipid Peroxidation; Lysine; Proteins; Pyrroles; Time Factors

2003
Model studies on protein side chain modification by 4-oxo-2-nonenal.
    Chemical research in toxicology, 2003, Volume: 16, Issue:4

    Topics: Acetylcysteine; Aldehydes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Histidine; Imidazoles; Linoleic Acid; Lysine; Magnetic Resonance Spectroscopy; Oxygen; Proteins; Pyrroles; Ribonucleases; Stereoisomerism; Structure-Activity Relationship

2003
Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes.
    Endocrine journal, 2003, Volume: 50, Issue:1

    Topics: Acrolein; Adult; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Norleucine; Pyrroles; Smoking

2003
Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes.
    Pediatric research, 2003, Volume: 54, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adolescent; Adult; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles; Regression Analysis

2003
AMINO ACID TRANSPORT IN BLOOD CELLS. II. PATTERNS OF TRANSPORT OF SOME AMINO ACIDS IN MAMMALIAN RETICULOCYTES AND MATURE RED BLOOD CELLS.
    The Journal of laboratory and clinical medicine, 1965, Volume: 66

    Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Benzoates; Biological Transport; Blood Cells; Erythrocytes; Ethylmaleimide; Glycine; Histidine; Ion Transport; Lysine; Pharmacology; Potassium; Puromycin; Pyrroles; Rats; Research; Reticulocytes; Sodium

1965
High levels of urinary pentosidine, an advanced glycation end product, in children with acute exacerbation of atopic dermatitis: relationship with oxidative stress.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Dermatitis, Atopic; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles

2003
Influence of baking conditions and precursor supplementation on the amounts of the antioxidant pronyl-L-lysine in bakery products.
    Journal of agricultural and food chemistry, 2004, Jan-28, Volume: 52, Issue:2

    Topics: Antioxidants; Bread; Caseins; Cooking; Ethanol; Gas Chromatography-Mass Spectrometry; Glucose; Lysine; Pyrroles; Solubility

2004
Tomato paste fraction inhibiting the formation of advanced glycation end-products.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:1

    Topics: Arginine; Blotting, Western; Chemical Fractionation; Enzyme-Linked Immunosorbent Assay; Food; Glucose; Glycation End Products, Advanced; Lysine; Molecular Weight; Nitroblue Tetrazolium; Norleucine; Oxidation-Reduction; Pyrroles; Rutin; Serum Albumin, Bovine; Solanum lycopersicum; Spectrometry, Fluorescence

2004
Dissociation between urinary pyrraline and pentosidine concentrations in diabetic patients with advanced nephropathy.
    The Journal of laboratory and clinical medicine, 2004, Volume: 144, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; beta 2-Microglobulin; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Lysine; Pyrroles; Reference Values; Regression Analysis

2004
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
    Journal of biochemistry, 2004, Volume: 136, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors

2004
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
    Stroke, 2005, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis

2005
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
    Chemical research in toxicology, 2005, Volume: 18, Issue:5

    Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes

2005
Amino acid residues associated with enzymatic activities of the isomerizing phycoviolobilin-lyase PecE/F.
    Biochemistry, 2005, Jun-07, Volume: 44, Issue:22

    Topics: Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Histidine; Isomerism; Kinetics; Lyases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phycobilins; Phycocyanin; Protein Subunits; Pyrroles; Sequence Deletion; Tetrapyrroles; Tryptophan

2005
Immunohistochemical localization of advanced glycation end products in pinguecula.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles

2006
Influence of feeding malt, bread crust, and a pronylated protein on the activity of chemopreventive enzymes and antioxidative defense parameters in vivo.
    Journal of agricultural and food chemistry, 2005, Oct-19, Volume: 53, Issue:21

    Topics: Albumins; Animals; Antioxidants; Bread; Chemoprevention; Diet; Edible Grain; Glucuronosyltransferase; Glutathione Transferase; Glycation End Products, Advanced; Lysine; Male; Pyrroles; Rats; Rats, Wistar

2005
Isolation and synthesis of 4-bromopyrrole-2-carboxyarginine and 4-bromopyrrole-2-carboxy-N(epsilon)-lysine from the marine sponge Stylissa caribica.
    Journal of natural products, 2006, Volume: 69, Issue:1

    Topics: Alkaloids; Animals; Arginine; Caribbean Region; Lysine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrroles

2006
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Proteins; Case-Control Studies; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Neutrophils; Norleucine; Oxidative Stress; Protein Carbonylation; Pyrroles; Renal Dialysis; Respiratory Burst; Serum Albumin

2005
Advanced glycation end product deposits in climatic droplet keratopathy.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:1

    Topics: Antibodies, Monoclonal; Arginine; Cornea; Corneal Diseases; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Pyrroles

2007
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Amino Acid Sequence; Amino Acid Substitution; Crystallography, X-Ray; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Lysine; Magnesium; Models, Chemical; Propane; Protein Conformation; Pyrroles; Structure-Activity Relationship; Triazoles

2007
Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine.
    Archives of biochemistry and biophysics, 2007, Jul-01, Volume: 463, Issue:1

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dehydroascorbic Acid; Histidine; Imidazoles; Lens, Crystalline; Lysine; Maillard Reaction; Nuclear Magnetic Resonance, Biomolecular; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Tetroses

2007
Effect of tocopherols in the antioxidative activity of oxidized lipid-amine reaction products.
    Journal of agricultural and food chemistry, 2007, May-30, Volume: 55, Issue:11

    Topics: alpha-Tocopherol; Antioxidants; Gas Chromatography-Mass Spectrometry; Lipids; Lysine; Olive Oil; Phosphatidylethanolamines; Phosphatidylserines; Plant Oils; Pyrroles

2007
Novel inhibitor for fibroblast growth factor receptor tyrosine kinase.
    Bioorganic & medicinal chemistry letters, 2007, Sep-01, Volume: 17, Issue:17

    Topics: Chemistry, Pharmaceutical; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Fibroblast Growth Factor 1; Humans; Hydrogen Bonding; Indoles; JNK Mitogen-Activated Protein Kinases; Lysine; Models, Chemical; Molecular Conformation; Oxindoles; Propionates; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1

2007
Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis.
    Investigational new drugs, 2008, Volume: 26, Issue:6

    Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anticarcinogenic Agents; Antigens, Nuclear; Antioxidants; Biomarkers, Tumor; Bread; Carcinogens; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Lysine; Male; Precancerous Conditions; Pyrroles; Random Allocation; Rats; Rats, Wistar

2008
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin

2008
Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides.
    BMB reports, 2008, Jul-31, Volume: 41, Issue:7

    Topics: Amino Acid Sequence; Glycation End Products, Advanced; Glycolipids; Glycosides; Glycosylation; Imidazoles; Lysine; Models, Biological; Norleucine; Pyrroles; Schiff Bases; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization

2008
Inhibitory effect of bread crust antioxidant pronyl-lysine on two different categories of colonic premalignant lesions induced by 1,2-dimethylhydrazine.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2009, Volume: 18, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Bread; Colon; Lysine; Male; Precancerous Conditions; Pyrroles; Rats; Rats, Wistar

2009
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.
    Molecular & cellular proteomics : MCP, 2009, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Arginine; Autoantibodies; Biomarkers; Blood Proteins; Case-Control Studies; Chromatography, Liquid; Female; Fluorometry; Humans; Logistic Models; Lysine; Macular Degeneration; Male; Mass Spectrometry; Middle Aged; Pyrroles

2009
Chemopreventive efficacy of pronyl-lysine on lipid peroxidation and antioxidant status in rat colon carcinogenesis.
    Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Cecum; Colon; Colonic Neoplasms; Lipid Peroxidation; Lysine; Male; Pyrroles; Rats; Rats, Wistar

2009
Transport of free and peptide-bound pyrraline at intestinal and renal epithelial cells.
    Journal of agricultural and food chemistry, 2009, Jul-22, Volume: 57, Issue:14

    Topics: Alanine; Amino Acid Transport Systems; Animals; Biological Transport; Caco-2 Cells; Cell Line; Dipeptides; Epithelial Cells; Humans; Intestinal Mucosa; Kidney; Kidney Tubules, Proximal; Lysine; Norleucine; Opossums; Peptides; Pyrroles; Rats

2009
Novel yellow compounds, dilysyldipyrrolones A and B, formed from xylose and lysine by the Maillard reaction.
    Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:9

    Topics: Aminocaproates; Aminocaproic Acid; Chromatography, High Pressure Liquid; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Molecular; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Xylose

2009
Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation.
    FEBS letters, 2010, Jan-04, Volume: 584, Issue:1

    Topics: Aldehyde Dehydrogenase; Cell Line; Fibroblasts; Humans; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Neoplasm Proteins; Picolinic Acids; Pipecolic Acids; Pyrroles

2010
Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film.
    Analytical chemistry, 2010, Feb-01, Volume: 82, Issue:3

    Topics: Biosensing Techniques; Chelating Agents; Copper; DNA Probes; DNA, Viral; Electric Impedance; Electrochemical Techniques; Glucose Oxidase; HIV; Lysine; Microelectrodes; Nitrilotriacetic Acid; Nucleic Acid Hybridization; Pyrroles; Quartz

2010
Conditions for the formation of dilysyl-dipyrrolones A and B, and novel yellow dipyrrolone derivatives formed from xylose and amino acids in the presence of lysine.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:2

    Topics: Aminocaproates; Aminocaproic Acid; Hydrogen-Ion Concentration; Lysine; Maillard Reaction; Pyrroles; Solutions; Xylose

2011
Site-specific protein modifications through pyrroline-carboxy-lysine residues.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jun-28, Volume: 108, Issue:26

    Topics: Culture Media; Escherichia coli; Lysine; Nuclear Magnetic Resonance, Biomolecular; Proteins; Pyrroles

2011
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
    Immunobiology, 2011, Volume: 216, Issue:12

    Topics: Animals; CD13 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Dipeptidyl Peptidase 4; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Pyrroles; Pyrrolidines; Thiazoles; Transgenes

2011
Polyamines are traps for reactive intermediates in furan metabolism.
    Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11

    Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine

2011
New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis.
    Chembiochem : a European journal of chemical biology, 2011, Oct-17, Volume: 12, Issue:15

    Topics: Alkaloids; Animals; Axinella; Imidazoles; Lysine; Metabolic Networks and Pathways; Proline; Pyrroles

2011
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
    Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2

    Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels

2013
Formation mechanism and characterization of dilysyl-dipyrrolones, the Maillard-type yellow pigments.
    Food & function, 2013, Volume: 4, Issue:7

    Topics: Aminocaproates; Anti-Bacterial Agents; Antioxidants; Bacteria; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Molecular Structure; Pyrroles; Ribose; Xylose

2013
Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts.
    Amino acids, 2013, Volume: 45, Issue:2

    Topics: Diabetes Mellitus; Glycation End Products, Advanced; Isotope Labeling; Lysine; Mass Spectrometry; Norleucine; Pyrroles

2013
A novel amperometric biosensor based on a co-crosslinked L-lysine-α-oxidase/overoxidized polypyrrole bilayer for the highly selective determination of L-lysine.
    Analytica chimica acta, 2013, Sep-17, Volume: 795

    Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Electrochemical Techniques; Electrodes; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Polymers; Pyrroles

2013
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.
    Angewandte Chemie (International ed. in English), 2013, Dec-23, Volume: 52, Issue:52

    Topics: Acetylation; Histone Code; Histones; Humans; Lysine; Pyrroles

2013
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness

2014
The formation of pyrroline and tetrahydropyridine rings in amino acids catalyzed by pyrrolysine synthase (PylD).
    Angewandte Chemie (International ed. in English), 2014, Jul-28, Volume: 53, Issue:31

    Topics: Catalysis; Catalytic Domain; Ligases; Lysine; Pyridines; Pyrroles

2014
Lysine pyrrolation is a naturally-occurring covalent modification involved in the production of DNA mimic proteins.
    Scientific reports, 2014, Jun-18, Volume: 4

    Topics: Amino Acid Sequence; Animals; Benzothiazoles; Diamines; DNA; Ethidium; Female; Fluorescent Dyes; Humans; Immunoblotting; Lupus Erythematosus, Systemic; Lysine; Male; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Models, Molecular; Molecular Sequence Data; Molecular Structure; Organic Chemicals; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Pyrroles; Quinolines; Spectrometry, Fluorescence

2014
Quantification of l-lysine in cheese by a novel amperometric biosensor.
    Food chemistry, 2015, Feb-15, Volume: 169

    Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Cheese; Electrodes; Lysine; Polymers; Pyrroles

2015
N-acetyl lysine/glutathione-derived pyrroles as potential ex vivo biomarkers of bioactivated furan-containing compounds.
    Chemical research in toxicology, 2015, Mar-16, Volume: 28, Issue:3

    Topics: Activation, Metabolic; Animals; Bile; Biomarkers; Furans; Glutathione; Lysine; Male; Microsomes, Liver; Pyrroles; Rats, Sprague-Dawley

2015
Isolation, identification, and formation conditions of a novel Maillard yellowish pigment, pyrrolothiazolate.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:8

    Topics: Coloring Agents; Cysteine; Glucose; Lysine; Maillard Reaction; Pyrroles; Thiazines

2015
4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts.
    Journal of agricultural and food chemistry, 2015, Jun-03, Volume: 63, Issue:21

    Topics: Aldehydes; Arachis; Cooking; Hot Temperature; Lipids; Lysine; Molecular Structure; Peanut Oil; Plant Oils; Pyrroles

2015
Stability of Individual Maillard Reaction Products in the Presence of the Human Colonic Microbiota.
    Journal of agricultural and food chemistry, 2015, Aug-05, Volume: 63, Issue:30

    Topics: Adult; Bacteria; Colon; Female; Gastrointestinal Microbiome; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Norleucine; Pyridones; Pyrroles

2015
Propagation of conformational changes during μ-opioid receptor activation.
    Nature, 2015, Aug-20, Volume: 524, Issue:7565

    Topics: Allosteric Regulation; Animals; Binding Sites; Heterotrimeric GTP-Binding Proteins; Lysine; Mice; Models, Molecular; Morphinans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Single-Chain Antibodies; Structure-Activity Relationship; Substrate Specificity

2015
Lysine-doped polypyrrole/spider silk protein/poly(l-lactic) acid containing nerve growth factor composite fibers for neural application.
    Materials science & engineering. C, Materials for biological applications, 2015, Nov-01, Volume: 56

    Topics: Animals; Axons; Lactic Acid; Lysine; Male; Nanofibers; Nerve Growth Factor; Nerve Regeneration; Neurites; PC12 Cells; Polyesters; Polymers; Pyrroles; Rats; Rats, Wistar; Schwann Cells; Silk; Spiders; Tissue Scaffolds

2015
Formation and elimination of pyrraline in the Maillard reaction in a saccharide-lysine model system.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:7

    Topics: Carbohydrates; Hot Temperature; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Pyrroles; Time Factors

2016
Scavenging 4-Oxo-2-nonenal.
    Chemical research in toxicology, 2015, Oct-19, Volume: 28, Issue:10

    Topics: Aldehydes; Free Radical Scavengers; Lipid Peroxidation; Lysine; Proteins; Pyridoxamine; Pyrroles

2015
Free and Protein-Bound Maillard Reaction Products in Beer: Method Development and a Survey of Different Beer Types.
    Journal of agricultural and food chemistry, 2016, Sep-28, Volume: 64, Issue:38

    Topics: Amino Acids; Beer; Food Handling; Lysine; Maillard Reaction; Norleucine; Ornithine; Pyridones; Pyrimidines; Pyrroles; Tandem Mass Spectrometry

2016
Superoxide is the critical driver of DOPAL autoxidation, lysyl adduct formation, and crosslinking of α-synuclein.
    Biochemical and biophysical research communications, 2017, May-27, Volume: 487, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Binding Sites; Cross-Linking Reagents; Enzyme Activation; Lysine; Oxidation-Reduction; Oxygen; Protein Binding; Pyrroles; Reactive Oxygen Species; Superoxide Dismutase

2017
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
    Molecular & cellular proteomics : MCP, 2017, Volume: 16, Issue:10

    Topics: Aldehydes; Amides; Cell Line; Cysteine; Histone Code; Humans; Lipid Peroxidation; Lysine; Oxidation-Reduction; Proteome; Proteomics; Pyrroles; Schiff Bases

2017
Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Mar-20, Volume: 24, Issue:17

    Topics: Base Pairing; Base Sequence; Binding Sites; DNA; G-Quadruplexes; Guanine; Imidazoles; Ligands; Lysine; Nylons; Protons; Pyrroles; Thermodynamics

2018
Solid-Phase Synthesis of Pyrrole Derivatives through a Multicomponent Reaction Involving Lys-Containing Peptides.
    ACS combinatorial science, 2018, 04-09, Volume: 20, Issue:4

    Topics: Catalysis; Combinatorial Chemistry Techniques; Iron Compounds; Lysine; Microwaves; Molecular Structure; Nitrogen; Peptides; Pyrroles; Small Molecule Libraries; Solid-Phase Synthesis Techniques; Styrenes

2018
A novel approach for the selective analysis of l-lysine in untreated human serum by a co-crosslinked l-lysine-α-oxidase/overoxidized polypyrrole bilayer based amperometric biosensor.
    Bioelectrochemistry (Amsterdam, Netherlands), 2018, Volume: 124

    Topics: Allosteric Regulation; Amino Acid Oxidoreductases; Biosensing Techniques; Cross-Linking Reagents; Electrochemical Techniques; Enzymes, Immobilized; Humans; Kinetics; Lysine; Microscopy, Electron, Scanning; Oxidation-Reduction; Polymers; Pyrroles; Substrate Specificity

2018
Apolipoprotein E binds to and reduces serum levels of DNA-mimicking, pyrrolated proteins.
    The Journal of biological chemistry, 2019, 07-12, Volume: 294, Issue:28

    Topics: Adult; Amino Acid Sequence; Animals; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Biophysical Phenomena; DNA; Female; Humans; Hyperlipidemias; Kinetics; Lysine; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Mimicry; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Pyrroles

2019
Pyrraline Formation Modulated by Sodium Chloride and Controlled by Encapsulation with Different Coating Materials in the Maillard Reaction.
    Biomolecules, 2019, 11-10, Volume: 9, Issue:11

    Topics: Amylose; Deoxyglucose; Glucose; Glycation End Products, Advanced; Hot Temperature; Lysine; Maillard Reaction; Norleucine; Pyrroles; Sodium Chloride; Zea mays

2019
Effect of protein fortification on heat damage and occurrence of β-casomorphins in (un)digested donor human milk intended for nutrition of preterm infants.
    Food chemistry, 2020, Jun-01, Volume: 314

    Topics: Animals; Cattle; Digestion; Endorphins; Female; Food, Fortified; Hot Temperature; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lysine; Lysinoalanine; Milk Proteins; Milk, Human; Norleucine; Pasteurization; Pyrroles

2020
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
    Food chemistry, 2020, Jul-01, Volume: 317

    Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde

2020
The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.
    International journal of molecular sciences, 2020, Apr-28, Volume: 21, Issue:9

    Topics: Benzamides; Cell Survival; Cycloheximide; Gene Expression Regulation; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Lysine; NF-kappa B; Piperazines; Protein Kinase C; Protein Processing, Post-Translational; Protein Stability; Pyridines; Pyrroles; Sequestosome-1 Protein; Signal Transduction; Tumor Necrosis Factor-alpha; Ubiquitin Thiolesterase

2020
Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsine.
    Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 2020, Volume: 38, Issue:4

    Topics: Animals; Carcinogens; Immunologic Tests; Liver; Lysine; Mice; Proteins; Pyrroles; Pyrrolizidine Alkaloids

2020
Biophysical and mass spectrometry based characterization of methylglyoxal-modified myoglobin: Role of advanced glycation end products in inducing protein structural alterations.
    International journal of biological macromolecules, 2021, Dec-15, Volume: 193, Issue:Pt B

    Topics: Glycation End Products, Advanced; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Myoglobin; Norleucine; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Pyrroles; Pyruvaldehyde

2021
New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues.
    Bioorganic chemistry, 2022, Volume: 125

    Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Furans; Lysine; Pyrroles; Rats; Tandem Mass Spectrometry

2022
Structural characterisation and pH-dependent preference of pyrrole cross-link isoforms from reactions of oxoenal with cysteine and lysine side chains as model systems.
    Amino acids, 2023, Volume: 55, Issue:9

    Topics: Amines; Amino Acids; Cysteine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Isoforms; Pyrroles

2023