pyrroles and lysine
pyrroles has been researched along with lysine in 114 studies
Research
Studies (114)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (11.40) | 18.7374 |
| 1990's | 19 (16.67) | 18.2507 |
| 2000's | 41 (35.96) | 29.6817 |
| 2010's | 34 (29.82) | 24.3611 |
| 2020's | 7 (6.14) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Batlle, AM; Stella, AM | 1 |
| Barnsley, PG; Boyle, SM; Sells, BH | 1 |
| DeCaprio, AP; O'Neill, EA | 1 |
| Smith, IC | 1 |
| Barratt, MD; Chapman, D; Dodd, GH | 1 |
| Baxter, CS; Byvoet, P | 1 |
| Grunberger, D; Reich, E; Ward, DC | 1 |
| Peraino, C | 1 |
| Austic, RE; Nesheim, MC | 1 |
| Belcher, RV; Lockwood, WH; Rimington, C | 1 |
| Holbrook, JJ; Jeckel, R | 1 |
| Anthony, DC; Boekelheide, K; Graham, DG; Maschmann, NA; Richards, RG; Shaw, BR; Wolfram, JW | 1 |
| Monnier, VM; Nagaraj, RH | 1 |
| Hidalgo, FJ; Zamora, R | 1 |
| Miyata, S; Monnier, VM; Perry, G; Richey, PL; Sayre, LM; Smith, MA; Stern, D; Taneda, S; Yan, SD | 1 |
| Castellani, R; Perry, G; Richey, PL; Smith, MA | 1 |
| Bailey, AJ; Paul, RG | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV | 1 |
| Horie, K; Iida, Y; Maeda, K; Miyata, T; Sugiyama, S; Tanaka, H; Tsuyuki, M | 1 |
| DeCaprio, AP; Hauer, CR; Spink, DC; Zhu, M | 1 |
| Castellani, RJ; Cohen, ML; Harris, PL; Monnier, VM; Perry, G; Smith, MA | 1 |
| de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A | 1 |
| Deyl, Z; Miksík, I | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL | 1 |
| Block, C; Ferguson, K; Fogarty, J; Haas, C; Hampel, N; Ni, Z; Polak, J; Razmjouei, K; Seftel, AD; Vaziri, ND; Wang, RZ | 1 |
| Angelini, G; Dagna-Bricarelli, F; Dapino, D; Garibaldi, S; Odetti, P; Perry, G; Piombo, G; Smith, M; Tabaton, M; Traverso, N; Zaccheo, D | 1 |
| Boutaud, O; Brame, CJ; Oates, JA; Roberts, LJ; Salomon, RG | 1 |
| Beck, W; Deppisch, R; Hänsch, GM; Henle, T; Hergesell, O; Ritz, E | 1 |
| Kansal, MM; Liu, Y; Sayre, LM; Xu, G | 1 |
| Sayre, LM; Xu, G | 2 |
| Ames, JM; Hill, VM; Isaacs, NS; Ledward, DA | 1 |
| Angelini, G; Garibaldi, S; Marinelli, L; Menini, S; Norese, R; Odetti, P; Perry, G; Siedlak, S; Smith, MA; Tabaton, M; Traverso, N; Valentini, S; Zaccheo, D | 1 |
| Cattaneo, S; De Noni, I; Pellegrino, L | 1 |
| Alaiz, M; Hidalgo, FJ; Zamora, R | 1 |
| Cleveland, DW; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Liu, J; Nagai, R; Nakano, I; Nakashima, K; Ohama, E; Shibata, N; Takikawa, M | 1 |
| Assmann, M; Hochgürtel, M; Köck, M; Lindel, T | 1 |
| Brady, JD; Robins, SP | 1 |
| Faist, V; Hofmann, T; Lindenmeier, M | 1 |
| Costello, PJ; Henschke, PA | 1 |
| Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M | 1 |
| Hoff, HF; Hoppe, G; O'Neil, J; Salomon, RL; Wu, Z | 1 |
| Itakura, K; Uchida, K | 1 |
| Liu, J; Sayre, LM; Xu, G; Yuan, Q; Zhang, WH | 1 |
| Daimon, M; Hirata, A; Igarashi, M; Kameda, W; Kato, T; Ohnuma, H; Oizumi, T; Saitoh, T; Sugiyama, K; Yamaguchi, H | 1 |
| Beppu, M; Hata, I; Hiraoka, M; Kaji, M; Kawakami, H; Mayumi, M; Momoi, T; Sekine, K; Todoroki, Y; Tsukahara, H; Uchiyama, M; Yorifuji, T; Yoshihara, K | 1 |
| ARIMURA, GK; YUNIS, AA | 1 |
| Hiraoka, M; Ito, S; Mayumi, M; Noiri, E; Ohta, N; Sato, S; Shibata, R; Tsukahara, H | 1 |
| Hofmann, T; Lindenmeier, M | 1 |
| Aizawa, K; Hirano, K; Inakuma, T; Kiho, T; Usui, S | 1 |
| Aso, Y; Inukai, T; Sekine, K; Takanashi, K; Takebayashi, K; Yoshida, N; Yoshihara, K | 1 |
| Krzycki, JA | 1 |
| Ahmed, N; Horiuchi, S; Jono, T; Lin, X; Nagai, R; Takeya, M; Thornalley, PJ | 1 |
| Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W | 1 |
| Baer, BR; Henne, KR; Rettie, AE | 1 |
| Böhm, S; Bubenzer, C; Scheer, H; Wu, D; Zhang, L; Zhao, KH; Zhou, M | 1 |
| Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T | 1 |
| Erbersdobler, HF; Grothe, D; Hofmann, T; Lindenmeier, M; Somoza, V; Wenzel, E | 1 |
| Grube, A; Köck, M; Lichte, E | 1 |
| Anraku, M; Kitamura, K; Maruyama, T; Mera, K; Nakajou, K; Otagiri, M; Tomita, K | 1 |
| Amano, S; Fukayama, M; Kaji, Y; Nagai, R; Oshika, T; Takazawa, Y | 1 |
| Alves, CN; Andrés, J; Castillo, R; Martí, S; Moliner, V; Silla, E; Tuñón, I | 1 |
| Dai, Z; Monnier, VM; Nemet, I; Shen, W | 1 |
| Hidalgo, FJ; León, MM; Zamora, R | 1 |
| Boonyarat, C; Grierson, DS; Kammasud, N; Saiki, I; Sakurai, H; Tsunoda, S; Vajragupta, O | 1 |
| Aranganathan, S; Nalini, N; Panneer Selvam, J | 1 |
| Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP | 1 |
| Ahmad, W; Deng, Y; Li, L | 1 |
| Aranganathan, S; Nalini, N; Panneerselvam, J | 1 |
| Crabb, JW; Gu, J; Gu, X; Nagaraj, RH; Ni, J; Yuan, X; Yue, X | 1 |
| Aranganathan, S; Gopalan, R; Nalini, N; Selvam, JP | 1 |
| Brandsch, M; Geissler, S; Hellwig, M; Henle, T; Knütter, I; Peto, A | 1 |
| Murata, M; Ono, H; Sakamoto, J; Takenaka, M | 1 |
| Jakobs, C; Struys, EA | 1 |
| Baur, J; Cosnier, S; Defrancq, E; Gondran, C; Holzinger, M; Perrot, H | 1 |
| Murata, M; Nomi, Y; Ono, H; Sakamoto, J; Takenaka, M | 1 |
| Brock, A; Cellitti, SE; Chiu, HP; Crossgrove, T; Fan, Q; Geierstanger, BH; Grünewald, J; Hao, X; Jones, DH; Lesley, SA; Okach, L; Ou, W; Patterson, P; Quinn, LL; Uno, T | 1 |
| Ansorge, S; Bank, U; Biton, A; Brocke, S; Reinhold, D; Täger, M | 1 |
| Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM | 1 |
| Al Mourabit, A; Cachet, N; Genta-Jouve, G; Holderith, S; Jeffree, R; Oberhänsli, F; Teyssié, JL; Thomas, OP | 1 |
| Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J | 1 |
| Masuzaki, R; Murata, M; Nomi, Y; Ono, H; Otsuka, Y; Takenaka, M; Terasawa, N | 1 |
| Heilmann, M; Ilchmann, A; Toda, M; Vieths, S | 1 |
| Brimble, MA; Cooper, GJ; Woods, TM | 1 |
| Cataldi, TR; Ciriello, R; Guerrieri, A | 1 |
| Einsle, O; Gerhardt, S; Günther, S; Hügle, M; Jung, M; Lucas, X; Schmidtkunz, K; Schüle, R; Wohlwend, D | 1 |
| Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH | 1 |
| Bacher, A; Beck, P; Groll, M; Quitterer, F | 1 |
| Chikazawa, M; Hagihara, Y; Hioki, Y; Maruyama, S; Matsumi, N; Miyashita, H; Nakashima, F; Otaki, N; Shibata, T; Shimozu, Y; Uchida, K | 1 |
| Cataldi, TR; Ciriello, R; Crispo, F; Guerrieri, A | 1 |
| Gao, H; Hua, H; Li, C; Lin, D; Peng, Y; Zheng, J | 1 |
| Murata, M; Noda, K; Yamada, S | 1 |
| Globisch, M; Henle, T; Kaden, D | 1 |
| Bunzel, D; Franz, CM; Hellwig, M; Henle, T; Huch, M; Kulling, SE | 1 |
| Déméné, H; Granier, S; Huang, W; Kobilka, BK; Laeremans, T; Manglik, A; Mas, C; Sounier, R; Steyaert, J | 1 |
| Wang, K; Xing, Y; Yu, Q; Zhang, H | 1 |
| Fu, Q; Li, B; Li, L; Liang, Z; Xu, Z; Zhang, X | 1 |
| Amarnath, K; Amarnath, V | 1 |
| Hellwig, M; Henle, T; Witte, S | 1 |
| Bax, A; Levine, RL; Werner-Allen, JW | 1 |
| Fu, L; Liebler, DC; Liu, K; Porter, NA; Sun, R; Tallman, KA; Tian, C; Yang, J; Yang, Y | 1 |
| Li, H; Yu, SJ | 1 |
| Asamitsu, S; Bando, T; Hashiya, K; Obata, S; Phan, AT; Sugiyama, H | 1 |
| Albericio, F; de la Torre, BG; Govender, T; Gudimella, SK; Jad, YE | 1 |
| Ciriello, R; De Gennaro, F; Frascaro, S; Guerrieri, A | 1 |
| Chikazawa, M; Hioki, Y; Hirade, N; Hirose, S; Itakura, M; Kikuchi, R; Matsushita, T; Miyashita, H; Nagata, K; Shibata, T; Uchida, K; Yoshitake, J; Zhang, M | 1 |
| Chen, X; Lai, Y; Lei, C; Liang, Z; Yang, Y; Yang, Z; Zeng, Y | 1 |
| Cattaneo, S; De Noni, I; Mallardi, D; Masotti, F; Pica, V; Roggero, P; Stuknytė, M; Tabasso, C | 1 |
| Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q | 1 |
| Ha, J; Kim, M; Lee, J; Park, JS; Park, SH; Seo, D | 1 |
| Cheng, T; Li, N; Li, W; Lin, G; Wang, H; Yang, X; Zhang, F; Zheng, J | 1 |
| Banerjee, S | 1 |
| Ciesielska, K; Muńko, M; Pluskota-Karwatka, D | 1 |
| Ciesielska, K; Hoffmann, M; Muńko, M; Pluskota-Karwatka, D | 1 |
Reviews
7 review(s) available for pyrroles and lysine
| Article | Year |
|---|---|
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles | 1996 |
New biomarkers of Maillard reaction damage to proteins.
Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles | 1996 |
Advanced glycation end-products in diabetic nephropathy.
Topics: Animals; Arginine; Blood Glucose; Diabetic Nephropathies; Glycation End Products, Advanced; Glycosylation; Humans; Immunohistochemistry; Lysine; Norleucine; Proteins; Pyrroles | 1996 |
Post-translational non-enzymatic modification of proteins. I. Chromatography of marker adducts with special emphasis to glycation reactions.
Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Glycosylation; Imidazoles; Lysine; Malondialdehyde; Mass Spectrometry; Norleucine; Protein Processing, Post-Translational; Proteins; Pyrroles | 1997 |
Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases.
Topics: Amides; Codon; Corrinoids; Dimethylamines; Imines; Lysine; Methane; Methylamines; Methyltransferases; Models, Molecular; Pyrroles | 2004 |
The Maillard reaction and food allergies: is there a link?
Topics: Arginine; Dendritic Cells; Food Hypersensitivity; Glycation End Products, Advanced; Humans; Immunoglobulin E; Lysine; Maillard Reaction; Norleucine; Pyrroles; Receptors, Scavenger; T-Lymphocytes | 2014 |
Review of pentosidine and pyrraline in food and chemical models: formation, potential risks and determination.
Topics: Arginine; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Food Analysis; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Lysine; Molecular Structure; Norleucine; Pyrroles; Risk Factors; Uremia | 2018 |
Trials
1 trial(s) available for pyrroles and lysine
| Article | Year |
|---|---|
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde | 2003 |
Other Studies
106 other study(ies) available for pyrroles and lysine
| Article | Year |
|---|---|
Delta aminolaevulinate dehydratase: its mechanism of action.
Topics: Histidine; Lysine; Macromolecular Substances; Models, Biological; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Sulfhydryl Compounds | 1978 |
Synthesis of messenger RNA coding for elongation factors G and Ts during nutritional shift-up in Escherichia coli K-12.
Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Escherichia coli; Kinetics; Lysine; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Protein Biosynthesis; Pyrroles; Ribosomal Proteins; Ribosomes; RNA, Messenger; Transcription, Genetic; Tritium | 1976 |
Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2,5-hexanedione exposure.
Topics: Animals; Axons; Brain Stem; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Hexanones; In Vitro Techniques; Ketones; Lysine; Male; Pyrroles; Rats; Rats, Inbred Strains; Spinal Cord | 1985 |
A study of the conformational properties of bovine pancreatic ribonuclease A by electron paramagnetic resonance.
Topics: Animals; Binding Sites; Bromine; Cattle; Chemical Phenomena; Chemistry, Physical; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Imides; Lysine; Methods; Pancreas; Pyrroles; Ribonucleases; Temperature | 1968 |
A spin label for tyrosine residues.
Topics: Chemical Phenomena; Chemistry; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen-Ion Concentration; Imidazoles; Lysine; Peptides; Pyrroles; Tyrosine | 1969 |
Effects of carcinogens and other agents on histone methylation in rat liver nuclei by endogenous histone lysine methyltransferase.
Topics: Adenosine; Animals; Azo Compounds; Benz(a)Anthracenes; Carbon Radioisotopes; Carcinogens; Cell Nucleus; Dimethylformamide; Ethionine; Fluorenes; Histones; Homocysteine; Liver; Lysine; Mesylates; Methylation; Methyltransferases; Nitrosamines; Nitrosoguanidines; Nitrosourea Compounds; Pyrimidines; Pyrroles; Rats; Ribonucleosides; S-Adenosylmethionine | 1974 |
7-Deazanebularin. Coding properties of triplets and polynucleotides.
Topics: Adenine; Adenine Nucleotides; Amino Acids; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Genetic Code; Lysine; Nucleosides; Peptide Biosynthesis; Polynucleotides; Pyrimidines; Pyrroles; Ribonucleotides; Ribosomes; RNA, Transfer; Tritium | 1972 |
Functional properties of ornithine-ketoacid aminotransferase from rat liver.
Topics: Animals; Apoproteins; Binding Sites; Buffers; Carbon Isotopes; Carboxylic Acids; Catalysis; Drug Stability; Glutamates; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Liver; Lysine; Ornithine; Phosphates; Pyridoxal Phosphate; Pyridoxamine; Pyrroles; Rats; Time Factors; Transaminases; Tromethamine | 1972 |
Arginine, ornithine and proline metabolism of chicks: influence of diet and heredity.
Topics: Amino Acid Oxidoreductases; Amino Acids; Aminoisobutyric Acids; Animals; Arginase; Arginine; Chickens; Depression, Chemical; Diet; Glutamates; Histidine; Kidney; Liver; Lysine; Organ Specificity; Ornithine; Oxidoreductases; Proline; Pyrroles; Selection, Genetic; Species Specificity; Stimulation, Chemical; Threonine; Transaminases; Tyrosine | 1971 |
The excretion of porphyrin-peptide conjugates in porphyria variegata.
Topics: Adolescent; Adult; Aged; Bilirubin; Child; Child, Preschool; Chromatography, Paper; Cysteine; Feces; Female; Hematoporphyrins; Humans; Infant; Lysine; Male; Middle Aged; Peptides; Phenylalanine; Porphyrias; Porphyrins; Pyrroles | 1968 |
A peptide containing a reactive lysyl group from ox liver glutamate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Cattle; Chymotrypsin; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Lysine; Peptides; Pyrroles; Sulfur Isotopes; Trypsin | 1969 |
Studies of the molecular pathogenesis of hexane neuropathy. II. Evidence that pyrrole derivatization of lysyl residues leads to protein crosslinking.
Topics: Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanes; Hexanones; Lysine; Nervous System Diseases; Pyrroles | 1982 |
Protein modification by the degradation products of ascorbate: formation of a novel pyrrole from the Maillard reaction of L-threose with proteins.
Topics: Aminocaproates; Arginine; Blood Proteins; Caproates; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Fluorescence; Glycation End Products, Advanced; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Models, Chemical; Proteins; Pyrroles; Ribonuclease, Pancreatic; Spectrophotometry; Tetroses | 1995 |
Linoleic acid oxidation in the presence of amino compounds produces pyrroles by carbonyl amine reactions.
Topics: Aldehydes; Butylamines; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Epoxy Compounds; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Lipoxygenase; Lysine; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Pyrroles; Spectrometry, Fluorescence | 1995 |
Advanced Maillard reaction end products are associated with Alzheimer disease pathology.
Topics: Alzheimer Disease; Arginine; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Lysine; Maillard Reaction; Neurofibrillary Tangles; Norleucine; Pyrroles | 1994 |
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Topics: Aged; Aged, 80 and over; Arginine; Cerebral Cortex; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Heme Oxygenase (Decyclizing); Humans; Immunohistochemistry; Locus Coeruleus; Lysine; Microscopy, Immunoelectron; Middle Aged; Neurons; Norleucine; Oxidative Stress; Parkinson Disease; Pyrroles; Substantia Nigra | 1996 |
Characterization of glutathione conjugates of pyrrolylated amino acids and peptides by liquid chromatography-mass spectrometry and tandem mass spectrometry with electrospray ionization.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrochemistry; Glutathione; Hexanones; Lysine; Mass Spectrometry; Oligopeptides; Oxidation-Reduction; Pyrroles | 1997 |
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease.
Topics: Adolescent; Arginine; Astrocytes; Brain Diseases; Child; Cross-Linking Reagents; Crystallins; Demyelinating Diseases; Glycation End Products, Advanced; Humans; Inclusion Bodies; Lysine; Norleucine; Pyrroles | 1997 |
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases | 1997 |
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits | 1997 |
Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS.
Topics: Adult; Aged; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Electron Probe Microanalysis; Endothelium; Enzyme Induction; Erectile Dysfunction; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norleucine; Penis; Pyrroles | 1997 |
Early glycoxidation damage in brains from Down's syndrome.
Topics: Aldehydes; Amyloid beta-Protein Precursor; Arginine; Brain; Cerebral Cortex; Down Syndrome; Gestational Age; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lysine; Norleucine; Oxidation-Reduction; Oxidative Stress; Pyrroles; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 1998 |
Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway.
Topics: Chromatography, Liquid; Cross-Linking Reagents; Lysine; Mass Spectrometry; Oligopeptides; Prostaglandin H2; Prostaglandins E; Prostaglandins H; Pyrroles; Schiff Bases; Time Factors | 1999 |
Advanced glycated end-products (AGE) during haemodialysis treatment: discrepant results with different methodologies reflecting the heterogeneity of AGE compounds.
Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Female; Fluorescence; Glycation End Products, Advanced; Hemofiltration; Humans; Lysine; Male; Middle Aged; Molecular Weight; Norleucine; Pyrroles; Renal Dialysis | 1999 |
Rapid cross-linking of proteins by 4-ketoaldehydes and 4-hydroxy-2-alkenals does not arise from the lysine-derived monoalkylpyrroles.
Topics: Aldehydes; Animals; Cattle; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Hexanones; Lysine; Proteins; Pyrroles; Ribonuclease, Pancreatic; Schiff Bases; Serum Albumin, Bovine | 1999 |
Structural elucidation of a 2:2 4-ketoaldehyde-amine adduct as a model for lysine-directed cross-linking of proteins by 4-ketoaldehydes.
Topics: Aldehydes; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; Lysine; Methylamines; Models, Chemical; Molecular Conformation; Molecular Structure; Pyrroles; Schiff Bases | 1999 |
Effect of high hydrostatic pressure on the volatile components of a glucose-lysine model system.
Topics: Furans; Glucose; Hydrostatic Pressure; Ketones; Lysine; Models, Chemical; Pyrans; Pyrazines; Pyridines; Pyrroles; Volatilization | 1999 |
Lipoperoxidation is selectively involved in progressive supranuclear palsy.
Topics: Aged; Aldehydes; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxides; Lysine; Mesencephalon; Middle Aged; Norleucine; Pyrroles; Reference Values; Supranuclear Palsy, Progressive; tau Proteins; Thiobarbituric Acid Reactive Substances | 2000 |
Formation of protein bound lysine-derived galactosyl and glucosyl pyrroles in heated model systems.
Topics: Caseins; Chromatography, High Pressure Liquid; Dietary Carbohydrates; Food Analysis; Galactose; Glucose; Hot Temperature; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Protein Binding; Pyrroles; Reference Standards | 2000 |
Contribution of pyrrole formation and polymerization to the nonenzymatic browning produced by amino-carbonyl reactions.
Topics: alpha-Linolenic Acid; Amines; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Polymers; Pyrroles | 2000 |
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Animals; Arginine; Female; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Immunoelectron; Middle Aged; Mutation; Norleucine; Pyrroles; Superoxide Dismutase; Superoxide Dismutase-1 | 2000 |
Synthesis of the marine natural product nalpha-(4-bromopyrrolyl-2-carbonyl)-L-homoarginine, a putative biogenetic precursor of the pyrrole-imidazole alkaloids.
Topics: Alkaloids; Animals; Homoarginine; Hydroxylation; Imidazoles; Lysine; Magnetic Resonance Spectroscopy; Porifera; Pyrroles; Spectrometry, Mass, Fast Atom Bombardment | 2000 |
Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.
Topics: Avidin; Benzaldehydes; Binding Sites; Binding, Competitive; Biotinylation; Carboxylic Acids; Cathepsin K; Cathepsins; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Indicators and Reagents; Lysine; Mass Spectrometry; Models, Chemical; Papain; Peptides; Pyrroles; Trypsin | 2001 |
Cross-linking of proteins by 3-(trifluoromethyl)-2,5-hexanedione. Model studies implicate an unexpected amine-dependent defluorinative substitution pathway competing with pyrrole formation.
Topics: Cross-Linking Reagents; Hexanones; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Neurotoxins; Proteins; Pyrroles; Ribonucleases | 2002 |
Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modulating activity.
Topics: Antioxidants; Bread; Caco-2 Cells; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Malondialdehyde; NADPH-Ferrihemoprotein Reductase; Polymers; Proteins; Pyrroles | 2002 |
Mousy off-flavor of wine: precursors and biosynthesis of the causative N-heterocycles 2-ethyltetrahydropyridine, 2-acetyltetrahydropyridine, and 2-acetyl-1-pyrroline by Lactobacillus hilgardii DSM 20176.
Topics: Acetaldehyde; Acylation; Cations, Divalent; Deuterium; Ethanol; Fructose; Heterocyclic Compounds; Lactobacillus; Lysine; Metals; Ornithine; Pyridines; Pyrroles; Taste; Wine | 2002 |
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.
Topics: Acetylcysteine; Aldehydes; Animals; Arteriosclerosis; Biological Transport; Cathepsin B; Cholesterol Esters; Chromatography, Liquid; Humans; Intracellular Membranes; Lipoproteins, LDL; Lysine; Lysosomes; Macrophages, Peritoneal; Mice; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Pyrroles; Spectrometry, Mass, Electrospray Ionization | 2003 |
Lysine-derived fluorophores formed by autoxidation of linoleic acid.
Topics: Ascorbic Acid; Catalysis; Chromatography, High Pressure Liquid; Edetic Acid; Ferric Compounds; Fluoresceins; Imines; Linoleic Acid; Lipid Peroxidation; Lysine; Proteins; Pyrroles; Time Factors | 2003 |
Model studies on protein side chain modification by 4-oxo-2-nonenal.
Topics: Acetylcysteine; Aldehydes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Histidine; Imidazoles; Linoleic Acid; Lysine; Magnetic Resonance Spectroscopy; Oxygen; Proteins; Pyrroles; Ribonucleases; Stereoisomerism; Structure-Activity Relationship | 2003 |
Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes.
Topics: Acrolein; Adult; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Norleucine; Pyrroles; Smoking | 2003 |
Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adolescent; Adult; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles; Regression Analysis | 2003 |
AMINO ACID TRANSPORT IN BLOOD CELLS. II. PATTERNS OF TRANSPORT OF SOME AMINO ACIDS IN MAMMALIAN RETICULOCYTES AND MATURE RED BLOOD CELLS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Benzoates; Biological Transport; Blood Cells; Erythrocytes; Ethylmaleimide; Glycine; Histidine; Ion Transport; Lysine; Pharmacology; Potassium; Puromycin; Pyrroles; Rats; Research; Reticulocytes; Sodium | 1965 |
High levels of urinary pentosidine, an advanced glycation end product, in children with acute exacerbation of atopic dermatitis: relationship with oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Dermatitis, Atopic; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles | 2003 |
Influence of baking conditions and precursor supplementation on the amounts of the antioxidant pronyl-L-lysine in bakery products.
Topics: Antioxidants; Bread; Caseins; Cooking; Ethanol; Gas Chromatography-Mass Spectrometry; Glucose; Lysine; Pyrroles; Solubility | 2004 |
Tomato paste fraction inhibiting the formation of advanced glycation end-products.
Topics: Arginine; Blotting, Western; Chemical Fractionation; Enzyme-Linked Immunosorbent Assay; Food; Glucose; Glycation End Products, Advanced; Lysine; Molecular Weight; Nitroblue Tetrazolium; Norleucine; Oxidation-Reduction; Pyrroles; Rutin; Serum Albumin, Bovine; Solanum lycopersicum; Spectrometry, Fluorescence | 2004 |
Dissociation between urinary pyrraline and pentosidine concentrations in diabetic patients with advanced nephropathy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; beta 2-Microglobulin; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Lysine; Pyrroles; Reference Values; Regression Analysis | 2004 |
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors | 2004 |
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis | 2005 |
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2005 |
Amino acid residues associated with enzymatic activities of the isomerizing phycoviolobilin-lyase PecE/F.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Histidine; Isomerism; Kinetics; Lyases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phycobilins; Phycocyanin; Protein Subunits; Pyrroles; Sequence Deletion; Tetrapyrroles; Tryptophan | 2005 |
Immunohistochemical localization of advanced glycation end products in pinguecula.
Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles | 2006 |
Influence of feeding malt, bread crust, and a pronylated protein on the activity of chemopreventive enzymes and antioxidative defense parameters in vivo.
Topics: Albumins; Animals; Antioxidants; Bread; Chemoprevention; Diet; Edible Grain; Glucuronosyltransferase; Glutathione Transferase; Glycation End Products, Advanced; Lysine; Male; Pyrroles; Rats; Rats, Wistar | 2005 |
Isolation and synthesis of 4-bromopyrrole-2-carboxyarginine and 4-bromopyrrole-2-carboxy-N(epsilon)-lysine from the marine sponge Stylissa caribica.
Topics: Alkaloids; Animals; Arginine; Caribbean Region; Lysine; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrroles | 2006 |
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Proteins; Case-Control Studies; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Neutrophils; Norleucine; Oxidative Stress; Protein Carbonylation; Pyrroles; Renal Dialysis; Respiratory Burst; Serum Albumin | 2005 |
Advanced glycation end product deposits in climatic droplet keratopathy.
Topics: Antibodies, Monoclonal; Arginine; Cornea; Corneal Diseases; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Pyrroles | 2007 |
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Crystallography, X-Ray; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Lysine; Magnesium; Models, Chemical; Propane; Protein Conformation; Pyrroles; Structure-Activity Relationship; Triazoles | 2007 |
Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dehydroascorbic Acid; Histidine; Imidazoles; Lens, Crystalline; Lysine; Maillard Reaction; Nuclear Magnetic Resonance, Biomolecular; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Tetroses | 2007 |
Effect of tocopherols in the antioxidative activity of oxidized lipid-amine reaction products.
Topics: alpha-Tocopherol; Antioxidants; Gas Chromatography-Mass Spectrometry; Lipids; Lysine; Olive Oil; Phosphatidylethanolamines; Phosphatidylserines; Plant Oils; Pyrroles | 2007 |
Novel inhibitor for fibroblast growth factor receptor tyrosine kinase.
Topics: Chemistry, Pharmaceutical; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Fibroblast Growth Factor 1; Humans; Hydrogen Bonding; Indoles; JNK Mitogen-Activated Protein Kinases; Lysine; Models, Chemical; Molecular Conformation; Oxindoles; Propionates; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1 | 2007 |
Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anticarcinogenic Agents; Antigens, Nuclear; Antioxidants; Biomarkers, Tumor; Bread; Carcinogens; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Lysine; Male; Precancerous Conditions; Pyrroles; Random Allocation; Rats; Rats, Wistar | 2008 |
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin | 2008 |
Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides.
Topics: Amino Acid Sequence; Glycation End Products, Advanced; Glycolipids; Glycosides; Glycosylation; Imidazoles; Lysine; Models, Biological; Norleucine; Pyrroles; Schiff Bases; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization | 2008 |
Inhibitory effect of bread crust antioxidant pronyl-lysine on two different categories of colonic premalignant lesions induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Bread; Colon; Lysine; Male; Precancerous Conditions; Pyrroles; Rats; Rats, Wistar | 2009 |
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.
Topics: Aged; Aged, 80 and over; Arginine; Autoantibodies; Biomarkers; Blood Proteins; Case-Control Studies; Chromatography, Liquid; Female; Fluorometry; Humans; Logistic Models; Lysine; Macular Degeneration; Male; Mass Spectrometry; Middle Aged; Pyrroles | 2009 |
Chemopreventive efficacy of pronyl-lysine on lipid peroxidation and antioxidant status in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Cecum; Colon; Colonic Neoplasms; Lipid Peroxidation; Lysine; Male; Pyrroles; Rats; Rats, Wistar | 2009 |
Transport of free and peptide-bound pyrraline at intestinal and renal epithelial cells.
Topics: Alanine; Amino Acid Transport Systems; Animals; Biological Transport; Caco-2 Cells; Cell Line; Dipeptides; Epithelial Cells; Humans; Intestinal Mucosa; Kidney; Kidney Tubules, Proximal; Lysine; Norleucine; Opossums; Peptides; Pyrroles; Rats | 2009 |
Novel yellow compounds, dilysyldipyrrolones A and B, formed from xylose and lysine by the Maillard reaction.
Topics: Aminocaproates; Aminocaproic Acid; Chromatography, High Pressure Liquid; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Molecular; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Xylose | 2009 |
Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation.
Topics: Aldehyde Dehydrogenase; Cell Line; Fibroblasts; Humans; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Neoplasm Proteins; Picolinic Acids; Pipecolic Acids; Pyrroles | 2010 |
Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film.
Topics: Biosensing Techniques; Chelating Agents; Copper; DNA Probes; DNA, Viral; Electric Impedance; Electrochemical Techniques; Glucose Oxidase; HIV; Lysine; Microelectrodes; Nitrilotriacetic Acid; Nucleic Acid Hybridization; Pyrroles; Quartz | 2010 |
Conditions for the formation of dilysyl-dipyrrolones A and B, and novel yellow dipyrrolone derivatives formed from xylose and amino acids in the presence of lysine.
Topics: Aminocaproates; Aminocaproic Acid; Hydrogen-Ion Concentration; Lysine; Maillard Reaction; Pyrroles; Solutions; Xylose | 2011 |
Site-specific protein modifications through pyrroline-carboxy-lysine residues.
Topics: Culture Media; Escherichia coli; Lysine; Nuclear Magnetic Resonance, Biomolecular; Proteins; Pyrroles | 2011 |
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
Topics: Animals; CD13 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Dipeptidyl Peptidase 4; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Pyrroles; Pyrrolidines; Thiazoles; Transgenes | 2011 |
Polyamines are traps for reactive intermediates in furan metabolism.
Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine | 2011 |
New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis.
Topics: Alkaloids; Animals; Axinella; Imidazoles; Lysine; Metabolic Networks and Pathways; Proline; Pyrroles | 2011 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
Formation mechanism and characterization of dilysyl-dipyrrolones, the Maillard-type yellow pigments.
Topics: Aminocaproates; Anti-Bacterial Agents; Antioxidants; Bacteria; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Molecular Structure; Pyrroles; Ribose; Xylose | 2013 |
Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts.
Topics: Diabetes Mellitus; Glycation End Products, Advanced; Isotope Labeling; Lysine; Mass Spectrometry; Norleucine; Pyrroles | 2013 |
A novel amperometric biosensor based on a co-crosslinked L-lysine-α-oxidase/overoxidized polypyrrole bilayer for the highly selective determination of L-lysine.
Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Electrochemical Techniques; Electrodes; Hydrogen-Ion Concentration; Lysine; Oxidation-Reduction; Polymers; Pyrroles | 2013 |
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.
Topics: Acetylation; Histone Code; Histones; Humans; Lysine; Pyrroles | 2013 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
The formation of pyrroline and tetrahydropyridine rings in amino acids catalyzed by pyrrolysine synthase (PylD).
Topics: Catalysis; Catalytic Domain; Ligases; Lysine; Pyridines; Pyrroles | 2014 |
Lysine pyrrolation is a naturally-occurring covalent modification involved in the production of DNA mimic proteins.
Topics: Amino Acid Sequence; Animals; Benzothiazoles; Diamines; DNA; Ethidium; Female; Fluorescent Dyes; Humans; Immunoblotting; Lupus Erythematosus, Systemic; Lysine; Male; Mice, Inbred BALB C; Mice, Inbred MRL lpr; Models, Molecular; Molecular Sequence Data; Molecular Structure; Organic Chemicals; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Pyrroles; Quinolines; Spectrometry, Fluorescence | 2014 |
Quantification of l-lysine in cheese by a novel amperometric biosensor.
Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Cheese; Electrodes; Lysine; Polymers; Pyrroles | 2015 |
N-acetyl lysine/glutathione-derived pyrroles as potential ex vivo biomarkers of bioactivated furan-containing compounds.
Topics: Activation, Metabolic; Animals; Bile; Biomarkers; Furans; Glutathione; Lysine; Male; Microsomes, Liver; Pyrroles; Rats, Sprague-Dawley | 2015 |
Isolation, identification, and formation conditions of a novel Maillard yellowish pigment, pyrrolothiazolate.
Topics: Coloring Agents; Cysteine; Glucose; Lysine; Maillard Reaction; Pyrroles; Thiazines | 2015 |
4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts.
Topics: Aldehydes; Arachis; Cooking; Hot Temperature; Lipids; Lysine; Molecular Structure; Peanut Oil; Plant Oils; Pyrroles | 2015 |
Stability of Individual Maillard Reaction Products in the Presence of the Human Colonic Microbiota.
Topics: Adult; Bacteria; Colon; Female; Gastrointestinal Microbiome; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Norleucine; Pyridones; Pyrroles | 2015 |
Propagation of conformational changes during μ-opioid receptor activation.
Topics: Allosteric Regulation; Animals; Binding Sites; Heterotrimeric GTP-Binding Proteins; Lysine; Mice; Models, Molecular; Morphinans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Single-Chain Antibodies; Structure-Activity Relationship; Substrate Specificity | 2015 |
Lysine-doped polypyrrole/spider silk protein/poly(l-lactic) acid containing nerve growth factor composite fibers for neural application.
Topics: Animals; Axons; Lactic Acid; Lysine; Male; Nanofibers; Nerve Growth Factor; Nerve Regeneration; Neurites; PC12 Cells; Polyesters; Polymers; Pyrroles; Rats; Rats, Wistar; Schwann Cells; Silk; Spiders; Tissue Scaffolds | 2015 |
Formation and elimination of pyrraline in the Maillard reaction in a saccharide-lysine model system.
Topics: Carbohydrates; Hot Temperature; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Pyrroles; Time Factors | 2016 |
Scavenging 4-Oxo-2-nonenal.
Topics: Aldehydes; Free Radical Scavengers; Lipid Peroxidation; Lysine; Proteins; Pyridoxamine; Pyrroles | 2015 |
Free and Protein-Bound Maillard Reaction Products in Beer: Method Development and a Survey of Different Beer Types.
Topics: Amino Acids; Beer; Food Handling; Lysine; Maillard Reaction; Norleucine; Ornithine; Pyridones; Pyrimidines; Pyrroles; Tandem Mass Spectrometry | 2016 |
Superoxide is the critical driver of DOPAL autoxidation, lysyl adduct formation, and crosslinking of α-synuclein.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Binding Sites; Cross-Linking Reagents; Enzyme Activation; Lysine; Oxidation-Reduction; Oxygen; Protein Binding; Pyrroles; Reactive Oxygen Species; Superoxide Dismutase | 2017 |
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Topics: Aldehydes; Amides; Cell Line; Cysteine; Histone Code; Humans; Lipid Peroxidation; Lysine; Oxidation-Reduction; Proteome; Proteomics; Pyrroles; Schiff Bases | 2017 |
Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.
Topics: Base Pairing; Base Sequence; Binding Sites; DNA; G-Quadruplexes; Guanine; Imidazoles; Ligands; Lysine; Nylons; Protons; Pyrroles; Thermodynamics | 2018 |
Solid-Phase Synthesis of Pyrrole Derivatives through a Multicomponent Reaction Involving Lys-Containing Peptides.
Topics: Catalysis; Combinatorial Chemistry Techniques; Iron Compounds; Lysine; Microwaves; Molecular Structure; Nitrogen; Peptides; Pyrroles; Small Molecule Libraries; Solid-Phase Synthesis Techniques; Styrenes | 2018 |
A novel approach for the selective analysis of l-lysine in untreated human serum by a co-crosslinked l-lysine-α-oxidase/overoxidized polypyrrole bilayer based amperometric biosensor.
Topics: Allosteric Regulation; Amino Acid Oxidoreductases; Biosensing Techniques; Cross-Linking Reagents; Electrochemical Techniques; Enzymes, Immobilized; Humans; Kinetics; Lysine; Microscopy, Electron, Scanning; Oxidation-Reduction; Polymers; Pyrroles; Substrate Specificity | 2018 |
Apolipoprotein E binds to and reduces serum levels of DNA-mimicking, pyrrolated proteins.
Topics: Adult; Amino Acid Sequence; Animals; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Biophysical Phenomena; DNA; Female; Humans; Hyperlipidemias; Kinetics; Lysine; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Mimicry; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Pyrroles | 2019 |
Pyrraline Formation Modulated by Sodium Chloride and Controlled by Encapsulation with Different Coating Materials in the Maillard Reaction.
Topics: Amylose; Deoxyglucose; Glucose; Glycation End Products, Advanced; Hot Temperature; Lysine; Maillard Reaction; Norleucine; Pyrroles; Sodium Chloride; Zea mays | 2019 |
Effect of protein fortification on heat damage and occurrence of β-casomorphins in (un)digested donor human milk intended for nutrition of preterm infants.
Topics: Animals; Cattle; Digestion; Endorphins; Female; Food, Fortified; Hot Temperature; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lysine; Lysinoalanine; Milk Proteins; Milk, Human; Norleucine; Pasteurization; Pyrroles | 2020 |
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde | 2020 |
The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.
Topics: Benzamides; Cell Survival; Cycloheximide; Gene Expression Regulation; HEK293 Cells; HeLa Cells; HT29 Cells; Humans; Lysine; NF-kappa B; Piperazines; Protein Kinase C; Protein Processing, Post-Translational; Protein Stability; Pyridines; Pyrroles; Sequestosome-1 Protein; Signal Transduction; Tumor Necrosis Factor-alpha; Ubiquitin Thiolesterase | 2020 |
Antibody-based detection of lysine modification of hepatic protein in mice treated with retrorsine.
Topics: Animals; Carcinogens; Immunologic Tests; Liver; Lysine; Mice; Proteins; Pyrroles; Pyrrolizidine Alkaloids | 2020 |
Biophysical and mass spectrometry based characterization of methylglyoxal-modified myoglobin: Role of advanced glycation end products in inducing protein structural alterations.
Topics: Glycation End Products, Advanced; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Myoglobin; Norleucine; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Pyrroles; Pyruvaldehyde | 2021 |
New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues.
Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Furans; Lysine; Pyrroles; Rats; Tandem Mass Spectrometry | 2022 |
Structural characterisation and pH-dependent preference of pyrrole cross-link isoforms from reactions of oxoenal with cysteine and lysine side chains as model systems.
Topics: Amines; Amino Acids; Cysteine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Isoforms; Pyrroles | 2023 |