pyrroles and leucine
pyrroles has been researched along with leucine in 38 studies
Research
Studies (38)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (34.21) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 14 (36.84) | 24.3611 |
| 2020's | 3 (7.89) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Adams, E; Heacock, AM | 1 |
| Ciaramitaro, D; Eisenstein, D; Huxtable, R | 1 |
| Granger, AS; Kowaloff, EM; Phang, JM | 1 |
| Levy, J; Malaisse, WJ | 1 |
| Lundgren, D; Ogur, M | 1 |
| Armstrong, SJ; Zuckerman, AJ | 1 |
| Farber, E; Landay, M; Lee, TN; Liang, H; Lieberman, MW; Starr, R; Verbin, RS | 1 |
| Charlesworth, D; Hollán, SR; Lehmann, H; Lorkin, PA; Miltényi, M; Szelényi, JG | 1 |
| Diluiso, G; Farber, E; Goldblatt, PJ; Liang, H; Saez, LM; Verbin, RS | 1 |
| Bradley, TB; Rieder, RF | 1 |
| Chiga, M; Harris, C; Reddy, J; Svoboda, D | 1 |
| Battle, A; Fukuda, H; Riley, P; Washbrook, R | 1 |
| Angeletti, RH; Grubmeyer, C; Nieves, E; Schramm, VL; Shi, W; Wang, F | 1 |
| CANDELA, JL | 1 |
| CLAMP, JR; HOUGH, L | 1 |
| Bedynek, A; Bilz, S; Demant, T; Keller, U; Schmitz, M; Wagner, S | 1 |
| Moroder, L; Schaschke, N; Stern, I; Turk, D | 1 |
| Fukuhara, S; Ishibashi, T; Kamioka, M; Maruyama, Y; Matsuoka, I; Nagata, K; Ohkawara, H; Sakamoto, N; Sakamoto, T; Sugimoto, K; Sugimoto, N; Takuwa, Y; Yokoyama, K | 1 |
| Koelsch, R; Neubert, K; Stiebitz, B; Stöckel-Maschek, A | 1 |
| Sharp, JS; Tomer, KB | 1 |
| Bergeron, J; Couture, P; Deshaies, Y; Gagné, C; Hogue, JC; Lamarche, B; Tremblay, AJ | 1 |
| Chan, LN; Fiji, HD; Kwon, O; Tamanoi, F; Watanabe, M | 1 |
| Delamere, NA; Mandal, A; Shahidullah, M | 1 |
| Fischer, JW; Freudenberger, T; Kretschmer, I; Nagy, N; Niedworok, C; Reis, H; Röck, K; Rübben, H; Szarvas, T; Vom Dorp, F | 1 |
| Abogadie, FC; Bunnett, NW; Darby, B; Grace, MS; Lieu, T; McIntyre, P; Veldhuis, N | 1 |
| Merrill, L; Vizzard, MA | 1 |
| Bachelor, M; Carreno, FR; Cunningham, JT; Nedungadi, TP; Park, YH; Saxena, A | 1 |
| Chen, L; Du, Y; Hong, Z; Jie, P; Li, Y; Lin, L; Tian, Y; Zhou, L | 1 |
| Jo, AO; Križaj, D; MacAulay, N; Phuong, TT; Ryskamp, DA; Verkman, AS; Yarishkin, O | 1 |
| Fukuda, I; Hasegawa, M; Higashino, K; Hinata, M; Horita, N; Ikeda, M; Imai, M; Imai, S; Kanemasa, T; Minami, M; Morioka, Y; Morita, A; Sakaguchi, G; Sanaki, T; Soga, M; Tsuchida, J; Yamamoto, M; Yamane, S; Yoshioka, T | 1 |
| Chen, L; Du, Y; Huang, S; Men, C; Qi, M; Wang, Z; Wu, C; Zhou, L | 1 |
| Li, B; Liang, H; Ou-Yang, Q; Xu, M | 1 |
| Chen, D; Shen, J; Tan, T; Tu, L; Wang, S; Wang, Y | 1 |
| An, D; Chen, A; Chen, L; Du, Y; Li, Y; Sha, S; Wang, Z; Wu, C; Xu, W; Zhou, L; Zhu, Y | 1 |
| An, D; Chen, L; Men, C; Qi, M; Wang, Z; Xu, W; Zhan, Y; Zhou, L | 1 |
| Amano, T; Fujii, N; Honda, Y; Kenny, GP; Kondo, N; McGarr, GW; Nishiyasu, T | 1 |
| Ding, X; Fan, X; Han, J; Ning, L; Tang, S; Wang, C | 1 |
| He, KM; Pu, JT; Teng, ZY; Wu, YF; Zhang, DG; Zhang, T | 1 |
Trials
2 trial(s) available for pyrroles and leucine
| Article | Year |
|---|---|
Effects of atorvastatin versus fenofibrate on apoB-100 and apoA-I kinetics in mixed hyperlipidemia.
Topics: Adult; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Atorvastatin; Fenofibrate; Heptanoic Acids; Humans; Hyperlipidemias; Kinetics; Leucine; Lipids; Male; Middle Aged; Pyrroles | 2004 |
Differential effect of fenofibrate and atorvastatin on in vivo kinetics of apolipoproteins B-100 and B-48 in subjects with type 2 diabetes mellitus with marked hypertriglyceridemia.
Topics: Anticholesteremic Agents; Apolipoprotein B-100; Apolipoprotein B-48; Atorvastatin; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Fenofibrate; Heptanoic Acids; Humans; Hypertriglyceridemia; Kinetics; Leucine; Male; Middle Aged; Pyrroles; Triglycerides | 2008 |
Other Studies
36 other study(ies) available for pyrroles and leucine
| Article | Year |
|---|---|
Formation and excretion of pyrrole-2-carboxylic acid. Whole animal and enzyme studies in the rat.
Topics: Alcohol Oxidoreductases; Amino Acid Oxidoreductases; Amino Acids; Animals; Carboxylic Acids; Catalase; Cattle; Chromatography, Ion Exchange; D-Amino-Acid Oxidase; Guinea Pigs; Humans; Hydroxyproline; Kidney; Kinetics; Leucine; Liver; Proline; Pyrroles; Rats; Swine | 1975 |
The effect of a pyrrolizidine alkaloid, monocrotaline, and a pyrrole, dehydroretronecine, on the biochemical functions of the pulmonary endothelium.
Topics: Adenosine Monophosphate; Animals; Blood Pressure; Endothelium; Heart; In Vitro Techniques; Leucine; Lung; Male; Monocrotaline; Norepinephrine; Organ Size; Plants, Toxic; Pyrroles; Pyrrolizidine Alkaloids; Rats; Senecio; Serotonin; Time Factors; Tissue Distribution | 1978 |
Alterations in proline metabolic enzymes with mammalian development.
Topics: Aging; Animals; Carboxylic Acids; Female; Kidney; Kinetics; Leucine; Liver; Mitochondria, Liver; Organ Specificity; Oxidoreductases; Oxygenases; Pregnancy; Proline; Pyrroles; Rats; Stereoisomerism; Valine | 1976 |
The stimulus-secretion coupling of glucose-induced insulin release-XVII. Effects of sulfonylureas and diazoxide on insular biosynthetic activity.
Topics: Animals; Cyclohexanes; Cyclopentanes; Diazoxide; Glucose; Hormones; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Oxidation-Reduction; Peptide Biosynthesis; Proinsulin; Pyrazines; Pyrroles; Rats; Sulfonylurea Compounds; Tolbutamide | 1975 |
Amino acid inhibition of a 1 -pyrroline-5-carboxylate dehydrogenase preparation from beef kidney mitochondria.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; Animals; Cattle; Glutamates; Glycine; Kidney; Leucine; Mitochondria; Pyrroles; Serine; Valine | 1972 |
The effects of lasiocarpine, retrorsine and retronecine pyrrole on human embryo lung and liver cells in culture.
Topics: Alkaloids; Alkylation; Autoradiography; Cells, Cultured; DNA; Heterocyclic Compounds; Humans; Leucine; Liver; Lung; Mitosis; Protein Biosynthesis; Pyrroles; Pyrrolizidine Alkaloids; RNA; Thymidine; Time Factors; Tritium; Uridine | 1972 |
A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation.
Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Cycloheximide; Cytarabine; DNA; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Ketones; Leucine; Male; Mechlorethamine; Protein Biosynthesis; Proteins; Pyrroles; Radiation Effects; Rats; RNA; Thymidine; Time Factors | 1970 |
Unstable haemoglobin disease caused by Hb Santa Ana- 88 (F4) Leu leads to Pro.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Amino Acid Sequence; Anemia, Hemolytic; Blood Group Antigens; Blood Protein Electrophoresis; Cell Membrane Permeability; Cell Survival; Chemistry Techniques, Analytical; Child; Chromium Isotopes; Electrophoresis, Disc; Electrophoresis, Paper; Erythrocytes, Abnormal; Erythropoiesis; Glucosephosphate Dehydrogenase; Glutathione; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Hungary; Immunogenetics; Iron Isotopes; Leucine; Lipids; Male; Mutation; Proline; Pyrroles | 1970 |
Effects of inhibitors of protein synthesis on structure and function of the crypts of the small intestine.
Topics: Animals; Autoradiography; Carbon Isotopes; Cycloheximide; DNA; Epithelial Cells; Epithelium; Histocytochemistry; Intestine, Small; Ketones; Leucine; Male; Microscopy, Electron; Mitosis; Protein Biosynthesis; Proteins; Pyrroles; Rats; RNA; Uridine | 1971 |
Hemoglobin Gun Hill: an unstable protein associated with chronic hemolysis.
Topics: Adult; Blood Cell Count; Blood Protein Electrophoresis; Carbon Isotopes; Child; Chromium Isotopes; Feces; Female; Hematocrit; Heme; Hemoglobinometry; Hemoglobins, Abnormal; Humans; Iron Isotopes; Jaundice; Leucine; Male; Nitrogen; Pyrroles; Reticulocytes; Urobilinogen; White People | 1968 |
Polyribosome disaggregation in rat liver by lasiocarpine.
Topics: Alkaloids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cycloheximide; Leucine; Liver; Male; Orotic Acid; Protein Biosynthesis; Pyrroles; Rats; Ribosomes; Time Factors | 1969 |
Stimulation of tetrapyrrole synthesis in mammalian epithelial cells in culture by exposure to aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Cattle; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Epithelium; gamma-Aminobutyric Acid; Glutamic Acid; Heme; Kinetics; Leucine; Mammals; Pyrroles; Radioisotope Dilution Technique; Tetrapyrroles | 1997 |
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Chromatography, High Pressure Liquid; Deuterium; Diphosphates; Enzyme Inhibitors; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Leucine; Macromolecular Substances; Magnesium; Magnesium Compounds; Mass Spectrometry; Molecular Sequence Data; Pepsin A; Peptide Fragments; Phenylalanine; Protons; Pyrimidinones; Pyrroles | 2001 |
[INSULIN SECRETION IN VIVO AND IN VITRO].
Topics: Alloxan; Coenzymes; Dogs; Glucose; In Vitro Techniques; Insulin; Leucine; Metabolism; Pharmacology; Phosphocreatine; Pyrroles; Pyruvates; Rabbits; Research | 1964 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft.
Topics: Animals; Binding Sites; Cathepsin B; Cattle; Crystallography, X-Ray; Cysteine Proteinase Inhibitors; Dipeptides; Epoxy Compounds; Kidney; Leucine; Molecular Conformation; Molecular Structure; Oligopeptides; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Pyridines; Pyrroles | 2004 |
Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.
Topics: Actins; Aorta; Atorvastatin; Blotting, Western; Cells, Cultured; Cytoskeleton; Densitometry; Detergents; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Guanosine Diphosphate; Guanosine Triphosphate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leucine; Lipid Metabolism; Octoxynol; Polyethylene Glycols; Protein Prenylation; Pyrroles; rhoA GTP-Binding Protein; Signal Transduction; Thrombin; Time Factors | 2005 |
Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: Synthesis and kinetic characterization as aminopeptidase P inhibitors.
Topics: Amino Acids; Aminopeptidases; Animals; Binding Sites; Escherichia coli; Kinetics; Leucine; Proline; Protease Inhibitors; Pyrroles; Rats; Structure-Activity Relationship; Substrate Specificity; Thiazoles | 2005 |
Effects of anion proximity in peptide primary sequence on the rate and mechanism of leucine oxidation.
Topics: Amino Acid Sequence; Anions; Free Radicals; Leucine; Mass Spectrometry; Molecular Structure; Molecular Weight; Oxidation-Reduction; Peptides; Pyrroles | 2006 |
Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Catalysis; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytoskeleton; Cytosol; Drug Discovery; Enzyme Inhibitors; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Leucine; Mice; NIH 3T3 Cells; Phosphines; Protein Prenylation; Protein Transport; Pyridines; Pyrroles; rhoA GTP-Binding Protein; Sulfonamides | 2011 |
TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity.
Topics: Adenosine Triphosphate; Animals; Calcium; Connexin 43; Connexins; Dose-Response Relationship, Drug; Enzyme Activation; Epithelium; Eye Proteins; Glycyrrhetinic Acid; Lens, Crystalline; Leucine; Morpholines; Osmotic Pressure; Probenecid; Propidium; Pyrroles; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Sulfonamides; Swine; Time Factors; Tissue Culture Techniques; TRPV Cation Channels | 2012 |
Inhibitory role of the small leucine-rich proteoglycan biglycan in bladder cancer.
Topics: Animals; Biglycan; Gene Expression Regulation, Neoplastic; Humans; Indoles; Leucine; Male; Mice; Mice, Nude; Niacinamide; Phenylurea Compounds; Pyrroles; RNA, Messenger; Sorafenib; Sunitinib; Urinary Bladder Neoplasms | 2013 |
The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo.
Topics: Animals; HEK293 Cells; Humans; Hyperalgesia; Leucine; Male; Mice, Inbred C57BL; Morpholines; Oligopeptides; Pain; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, PAR-2; Sulfonamides; TRPV Cation Channels; Trypsin | 2014 |
Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats.
Topics: Administration, Intravesical; Animals; Disease Models, Animal; Gene Expression Regulation; Leucine; Male; Morpholines; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Time Factors; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Incontinence, Stress; Urodynamics; Urological Agents | 2014 |
Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells.
Topics: Angiotensin II; Animals; Calcium; Cell Line; Cells, Cultured; Hypothalamus; Leucine; Membrane Microdomains; Morpholines; Protein Transport; Pyrroles; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; src-Family Kinases; Sulfonamides; TRPV Cation Channels | 2014 |
Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways.
Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Down-Regulation; Enzyme Activation; Hippocampus; Imidazoles; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Leucine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Morpholines; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; TRPV Cation Channels | 2015 |
TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.
Topics: Animals; Aquaporin 4; Calcium; Calcium Signaling; Cell Size; Gene Expression; Homeostasis; Leucine; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Neuroglia; Oocytes; Potassium Channels, Inwardly Rectifying; Pyrroles; Retina; Sulfonamides; TRPV Cation Channels; Water; Xenopus | 2015 |
Sensitization of transient receptor potential vanilloid 4 and increasing its endogenous ligand 5,6-epoxyeicosatrienoic acid in rats with monoiodoacetate-induced osteoarthritis.
Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Ganglia, Spinal; Hand Strength; Iodoacetic Acid; Leucine; Male; Morpholines; Neurons; Osteoarthritis; Pain; Pain Measurement; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; TRPV Cation Channels | 2018 |
Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Evoked Potentials; Glycine; Hippocampus; Leucine; Mice; Mice, Inbred ICR; Morpholines; Patch-Clamp Techniques; Protein Kinase C; Pyramidal Cells; Pyrroles; Receptors, Glycine; Signal Transduction; Strychnine; Sulfonamides; TRPV Cation Channels | 2018 |
TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling.
Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Glioma; Humans; Leucine; Morpholines; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Pyrroles; rac1 GTP-Binding Protein; Signal Transduction; Sulfonamides; TRPV Cation Channels | 2018 |
TRPV4 channels stimulate Ca
Topics: Animals; Apoptosis; Brain Injuries; Calcium; Cell Death; Cell Survival; Cerebral Hemorrhage; Endoplasmic Reticulum Stress; Inositol 1,4,5-Trisphosphate Receptors; Leucine; Male; Mice; Mice, Inbred C57BL; Morpholines; Neurons; Pyrroles; Sulfonamides; TRPV Cation Channels; Unfolded Protein Response | 2019 |
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice.
Topics: Animals; Astrocytes; Epilepsy, Temporal Lobe; Inflammasomes; Inflammation; Leucine; Male; Mice; Mice, Inbred ICR; Microglia; Morpholines; Neurons; Pilocarpine; Pyrroles; Status Epilepticus; Sulfonamides; TRPV Cation Channels | 2019 |
Transient receptor potential vanilloid 4 is involved in the upregulation of connexin expression following pilocarpine-induced status epilepticus in mice.
Topics: Animals; Connexin 43; Connexins; Epilepsy; Gap Junction beta-1 Protein; Hippocampus; Leucine; Male; Mice; Mice, Inbred ICR; Morpholines; Pilocarpine; Pyrroles; Status Epilepticus; Sulfonamides; TRPV Cation Channels | 2019 |
TRPV4 channel blockade does not modulate skin vasodilation and sweating during hyperthermia or cutaneous postocclusive reactive and thermal hyperemia.
Topics: Adult; Female; Humans; Hyperemia; Hyperthermia; Leucine; Male; Membrane Transport Modulators; Microdialysis; Morpholines; Piperidines; Pyrroles; Quinolines; Regional Blood Flow; Skin; Sulfonamides; Sweating; Time Factors; TRPV Cation Channels; Vasodilation; Young Adult | 2021 |
Role of TRPV4-P2X7 Pathway in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion.
Topics: Animals; Ganglia, Spinal; Hyperalgesia; Leucine; Male; Morpholines; Nerve Compression Syndromes; Neuralgia; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Wistar; Receptors, Purinergic P2X7; Rosaniline Dyes; Signal Transduction; Sulfonamides; TRPV Cation Channels | 2021 |
Transient receptor potential vanilloid 4 promotes the growth of non-small cell lung cancer by regulating Foxp3.
Topics: A549 Cells; Aged; Apoptosis; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Female; Forkhead Transcription Factors; Humans; Leucine; Lung Neoplasms; Male; Middle Aged; Morpholines; Pyrroles; Sulfonamides; TRPV Cation Channels | 2022 |