pyrroles has been researched along with kt 5720 in 375 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.27) | 18.7374 |
| 1990's | 109 (29.07) | 18.2507 |
| 2000's | 191 (50.93) | 29.6817 |
| 2010's | 73 (19.47) | 24.3611 |
| 2020's | 1 (0.27) | 2.80 |
| Authors | Studies |
|---|---|
| Kamei, C; Mukai, T; Tasaka, K | 1 |
| Doi, M; Mio, M; Nonaka, T; Tasaka, K | 1 |
| Deguchi, K; Komada, F; Morita, K; Nishikawa, M; Shirakawa, S | 1 |
| Hayashi, T; Kato, H; Koshino, Y; Kutsumi, Y; Miyabo, S; Nakai, T | 1 |
| Gray, LS; Haverstick, DM | 1 |
| Berridge, MV; Tan, AS | 1 |
| Bradbury, EM; Crissman, HA; Gadbois, DM; Tobey, RA | 1 |
| Deguchi, K; Nishikawa, M; Saitoh, M; Shirakawa, S | 1 |
| Hara, H; Kogure, K; Matsuda, Y; Onodera, H; Yoshidomi, M | 1 |
| Hatase, O; Irino, S; Norman, AW; Taoka, T; Tasaka, T; Tokuda, M | 1 |
| Jikoh, Y; Nishio, H; Okugawa, K; Segawa, T | 1 |
| Fukuzaki, H; Shuntoh, H; Tanaka, C; Taniyama, K | 1 |
| Deguchi, K; Kobayashi, K; Nishikawa, M; Omay, SB; Shirakawa, S; Toyoda, H | 1 |
| Pratt, MM; Salathe, M; Wanner, A | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Fukushima, N; Hayashi, C; Katayama, T; Misu, Y; Miyamae, T; Ueda, H | 1 |
| Morita, I; Murota, S; Nakahama, K | 1 |
| Bell, LL; Cheung, JY; Lynch, CJ; Miller, BA | 1 |
| Hirokawa, N; Okada, Y; Sato-Yoshitake, R | 1 |
| Gotoh, H | 1 |
| Absood, A; Maruno, K; Said, SI | 1 |
| Fujiwara, R; Miyabo, S; Nakai, T; Shimada, A; Tamai, T | 1 |
| Audesirk, G; Cabell, L | 1 |
| Abraham, I; McCroskey, MC; Sampson, KE | 1 |
| Marquardt, DL; Walker, LL | 1 |
| Galski, H; Gottesman, MM; Hochman, J; Lazarovici, P; Matsuda, Y; Murakata, C | 1 |
| Aston-Jones, G; Shiekhattar, R | 1 |
| Morton, DM; Tchao, R | 1 |
| McKee, M; Nathanson, JA; Scanlon, C; Scavone, C | 1 |
| Castillo, PE; Nicoll, RA; Weisskopf, MG; Zalutsky, RA | 1 |
| Abraham, I; Aristoff, PA; Laborde, AL; Sampson, KE; Shelly, JA; Skulnick, HI; Wolf, CL | 1 |
| Foegh, ML; Fournier, RS; Josephs, MD; Leszczynski, D | 1 |
| Mio, M; Nakaya, N; Shimazawa, M; Tasaka, K | 1 |
| Grimaldi, M; Navarra, P; Pozzoli, G; Preziosi, P; Schettini, G | 1 |
| Lee, JC; White, JR | 1 |
| Matthies, H; Reymann, KG | 1 |
| Herman, MD; Narahashi, T; Reuveny, E | 1 |
| Bamba, N; Hishinuma, A; Kasai, K; Shimoda, SI; So, S; Yamanaka, T | 1 |
| Basson, MD; Hong, F | 1 |
| Catravas, JD; Del Monte, MA; Marczin, N; Miyamoto, Y | 1 |
| Cronstein, BN; Landau, S; Montesinos, MC; Naime, D; Revan, S | 1 |
| Komalavilas, P; Lincoln, TM | 1 |
| Carper, HT; Mandell, GL; Sullivan, GW | 1 |
| Kawakami, T; Takenaka, T | 1 |
| Finkel, MS; Hattler, BG; Oddis, CV; Simmons, RL | 1 |
| Navaratnam, DS; Oberholtzer, JC; Scott, SP; Su, HS | 1 |
| Kampine, JP; Mizoguchi, H; Narita, M; Tseng, LF | 1 |
| Bengis-Garber, C; Gruener, N | 1 |
| Akeson, WH; Amiel, D; Sung, KL; Whittemore, DE; Yang, L | 1 |
| Satake, N; Shibata, M; Shibata, S | 1 |
| Davis, FB; Davis, PJ; Lin, HY; Thacorf, HR | 1 |
| Sansom, SC; Stockand, JD | 1 |
| Goligorsky, MS; Malbon, CC; Wang, Hy | 1 |
| Bernstein, MA; Welch, SP | 1 |
| Joe, CO; Kang, KW; Kim, DY; Koo, SK; Park, SD | 1 |
| Hruska, K; Onishi, T | 1 |
| al-Rashed, S; Hellewell, PG; Rossi, AG; Teixeira, MM | 1 |
| Kubokawa, M; Kubota, T; Mori, Y | 1 |
| Kamisato, S; Okamoto, K; Takami, N; Uemura, Y | 1 |
| Cikós, T; Kalthoff, H; Krull, NB; Ungefroren, H | 1 |
| Haikala, H; Kaheinen, P; Levijoki, J; Lindén, IB | 1 |
| Akagi, M; Akagi, R; Fukuishi, N; Matsuura, S; Nakagawa, C; Sakaguchi, M | 1 |
| Ardenghi, P; Izquierdo, I; Izquierdo, LA; Medina, JH; Netto, CA; Quevedo, J; Schröder, N | 1 |
| Allen, LF; Fatima, S; Kan, H; Malik, KU; Parmentier, JH; Ruan, Y | 1 |
| Fein, A; Tertyshnikova, S | 1 |
| Anwer, MS; Webster, CR | 1 |
| Kim, JH; Pierce, SK; Wagle, NM | 1 |
| Endo, K; Nakamura, M; Nakata, K | 1 |
| Chakrabarti, S; Law, PY; Loh, HH | 1 |
| McCarthy, TL; Millet, I; Vignery, A | 1 |
| Asano, Y; Homma, S; Iimura, O; Ikeda, U; Kusano, E; Shimada, K; Takeda, S | 1 |
| Hoffmann, EK; Jakobsen, LD; Jensen, BS; Krarup, T | 1 |
| Abraham, I; Olsen, MK; Reszka, AA | 1 |
| May, K; Sisson, JH; Spurzem, JR; Wyatt, TA | 1 |
| Coleman, R; Roma, MG; Shaw, R; Stone, V | 1 |
| Allescher, HD; Franck, H; Huber, A; Ruth, P; Schusdziarra, V; Storr, M; Trudrung, P | 1 |
| Polte, T; Schröder, H | 1 |
| Anderson, R; Feldman, C; Mahomed, AG; Theron, AJ | 1 |
| Huang, LJ; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Izquierdo, I; Jerusalinsky, D; Quevedo, J; Quillfeldt, JA; Roesler, R; Vianna, M; Zanatta, MS | 1 |
| Ardenghi, P; Barros, D; Bevilaqua, L; Izquierdo, I; Izquierdo, LA; Madruga, M; Medina, JH; Quevedo, J; Rodrigues, C; Schröder, N | 1 |
| Ardenghi, P; Bevilaqua, L; Bianchin, M; Bromberg, E; Izquierdo, I; Medina, JH; Quevedo, J; Schaeffer, E; Schmitz, PK; Schröder, N; Walz, R | 1 |
| de Koster, BM; Elferink, JG | 1 |
| Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R | 1 |
| Kubokawa, M; Kubota, T; Mori, Y; Nakamura, K; Nakaya, S; Sato, F; Yoshioka, Y | 1 |
| Cai, D; De Bellard, M; Filbin, MT; Shen, Y; Tang, S | 1 |
| Narahashi, T; Oyaizu, M | 1 |
| Amoroso, S; Annunziato, L; Cataldi, M; Colao, AM; D'Alessio, A; Di Renzo, GF; Sarnacchiaro, F; Secondo, A | 1 |
| Bryce, PJ; Dascombe, MJ; Hutchinson, IV | 1 |
| Dessauer, CW; Hume, JR; Keef, KD; Zhong, J | 1 |
| Kamei, J; Ohsawa, M | 2 |
| Boulanger, L; Poo, MM | 1 |
| Day, BN; Green, KM; Kim, JH; Prather, RS; Wang, WH | 1 |
| Kamei, J; Ohsawa, M; Tanaka, S | 1 |
| Carbajal, ME; Nguyen, B; Vitale, ML | 1 |
| Ahn, S; Ginty, DD; Linden, DJ | 1 |
| Brown, EJ; Wang, J | 1 |
| Ohuchi, K; Yamaki, K | 1 |
| Shahidullah, M; Wilson, WS | 1 |
| Malaquias, AT; Oliveira, MM | 1 |
| Broussas, M; Cornillet-Lefèbvre, P; Nguyen, P; Potron, G | 1 |
| Ito, Y; Marunaka, Y; Niisato, N | 1 |
| Izquierdo, I; Medina, JH; Netto, CA; Schröder, N | 1 |
| Hume, JR; Keef, KD; Zhong, J | 1 |
| Cassiman, JJ; Clauss, W; Cuppens, H; Van Driessche, W; Weber, WM | 1 |
| Anwyl, R; Huang, LQ; Rowan, MJ | 1 |
| Jo, H; Komalavilas, P; Lincoln, TM; Shah, PK | 1 |
| Kimura, H | 1 |
| Feijge, MA; Heemskerk, JW; Keularts, IM; van Gorp, RM; Vuist, WM | 1 |
| Heires, P; Rennard, SI; Romberger, DJ; Wyatt, TA | 1 |
| Diefenbach, TJ; Guthrie, PB; Kater, SB | 1 |
| Ardenghi, P; Barros, DM; Izquierdo, I; Izquierdo, LA; Medinam, JH; Mello e Souza, T; Rodrigues, C; Sant'Anna, MK; Vianna, M | 1 |
| Choi, BM; Chung, HT; Jun, CD; Jung, BH; Kim, YC; Kim, YM; Oh, GS; Pae, HO; Park, R; So, HS; Yoo, JC | 1 |
| Hirsch, JR; Hohendahl, A; Saleh, H; Schlatter, E; Schulte, EA; Stegemann, H | 1 |
| Agematsu, K; Hokibara, S; Komiyama, A; Nagumo, H; Nakazawa, T; Shinozaki, K; Yasui, K | 1 |
| Barros, DM; Izquierdo, I; Izquierdo, LA; Medina, JH; Vianna, MR | 1 |
| Dhanakoti, SN; Gao, Y; Nguyen, MQ; Raj, JU | 1 |
| Bellon, G; Fawzi, A; Kefalides, NA; Monboisse, JC; Robinet, A; Ziaie, Z | 1 |
| Dick, JM; Lefebvre, RA | 1 |
| Friedland, JS; Shaw, TC; Thomas, LH | 1 |
| Birdsall, NJ; Lazareno, S; Popham, A | 1 |
| Aoki, T; Mizoguchi, H; Narita, M; Ohsawa, M; Suzuki, T; Tseng, LF | 1 |
| Derweesh, IH; Weiss, RM; Wheeler, MA | 1 |
| Chung, HT; Kim, SB; Lee, HS; Pae, HO; Seo, WG; Shin, M | 1 |
| Huang, YY; Kandel, ER; Martin, KC | 1 |
| Casadei, B; Musialek, P; Paterson, DJ; Rigg, L; Terrar, DA | 1 |
| Kamei, C; Kirino, Y; Mio, M | 1 |
| Chun, JS; Kang, SS; Oh, CD; Yoon, YM | 1 |
| Gean, PW; Lin, HC; Luo, MZ; Wang, SJ | 1 |
| Fukao, M; Horowitz, B; Keef, KD; Kenyon, JL; Mason, HS | 1 |
| Arendshorst, WJ; Purdy, KE | 1 |
| Imamura, H; Inagaki, C; Kawasaki, H; Mishima, K; Otani, H | 1 |
| Hsu, WH; Prapong, T; Uemura, E | 1 |
| Gemba, M; Kohda, Y | 1 |
| Conde, M; Porras, T; Rosado, JA; Sage, SO | 1 |
| Birdsall, NJ; Lazareno, S; Popham, A; Saldanha, J | 1 |
| Akagawa, K; Kohara, K; Ogura, A; Yamaguchi, K | 1 |
| Chung, BS; Kang, CD; Kim, DW; Kim, SH; Lee, BG; Um, JH | 1 |
| Berezin, V; Bock, E; Jessen, U; Novitskaya, V; Pedersen, N; Serup, P | 1 |
| Bland, KI; Filardo, EJ; Frackelton, AR; Quinn, JA | 1 |
| Alpern, RJ; Amemiya, M; Ando, Y; Asano, Y; Kusano, E; Muto, S; Tabei, K | 1 |
| Isseroff, RR; Nuccitelli, R; Pullar, CE | 1 |
| Karle, CA; Kathöfer, S; Kiehn, J; Schoels, W; Zhang, W; Zitron, E | 1 |
| Dayer, JM; Friedland, JS; Price, NM; Shaw, TC | 1 |
| Brown, RE; Eriksson, KS; Haas, HL; Korotkova, TM | 1 |
| Makarevich, AV; Sirotkin, AV | 1 |
| Abe, T; Kamei, C; Mio, M; Shimada, K | 1 |
| Haneda, M; Inoki, K; Kikkawa, R; Koya, D; Maeda, S; Nishio, T | 1 |
| Ho, J; Lau, HK | 1 |
| Cho, KW; Cui, X; Jin, JY; Kim, SH; Kim, SZ; Lee, HS; Wen, JF; Xu, WX | 1 |
| Hirsh, JK; Silinsky, EM | 1 |
| Allescher, HD; Folmer, R; Kurjak, M; Schusdziarra, V; Storr, M | 1 |
| Fujita, N; Ishida, A; Kitazawa, R; Tsuruo, T | 1 |
| Jung, H; Kim, MS; Ko, CB; Lee, I; Lee, KM; Moon, BS; Park, R | 1 |
| Jones, SL | 1 |
| Coleman, R; Elias, E; Milkiewicz, P; Roma, MG | 1 |
| Abbruzzese, A; Beninati, S; Boccellino, M; Caraglia, M; D'Alessandro, AM; Giuberti, G; Lentini, A; Marra, M; Pepe, S | 1 |
| Ertl, RF; Kim, HJ; Kobayashi, T; Kohyama, T; Liu, X; Rennard, SI; Takizawa, H; Wen, FQ | 1 |
| Bełtowski, J; Górny, D; Marciniak, A; Wójcicka, G | 1 |
| Ellershaw, DC; Greenwood, IA; Large, WA | 1 |
| Fang, Q; Kim, HJ; Kobayashi, T; Kohyama, T; Liu, X; Rennard, SI; Wen, FQ; Wyatt, TA | 1 |
| Garber, MM; Heiman, AS | 1 |
| Hirano, J; Itazawa, S; Kubokawa, M; Nakamura, K | 1 |
| Arias, IM; Kagawa, T; Sai, Y; Varticovski, L | 1 |
| Banas, B; Bangen, P; Dohle, F; Heidenreich, S; Lang, D; Pauels, HG; Terstesse, M | 1 |
| Aguilar-Bryan, L; Bryan, J; Crane, A; Hu, M; Nakazaki, M; Seghers, V; Ullrich, S | 1 |
| Almeida, A; Bolanos, JP; Dello Russo, C; Feinstein, DL; Galea, E; Gavrilyuk, V; Palmer, J; Pelligrino, D; Weinberg, G | 1 |
| Aravamudan, B; Broadie, K | 1 |
| Alper, RH; Mize, AL | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Blanquet, PR; Derer, P; Mariani, J | 1 |
| Hsu, KS; Huang, CC | 1 |
| Abe, K; Misawa, M | 1 |
| Cao, C; Cho, KW; Han, JH; Kim, SH; Kim, SZ | 1 |
| Brailoiu, E; Dun, NJ; Miyamoto, MD | 1 |
| Dewey, WL; Elzey, MJ; Javed, RR; Smith, FL | 1 |
| Calixto, JB; El Sayah, M | 1 |
| Kwon, G; Marshall, CA; McDaniel, ML; Pappan, KL; Schaffer, JE | 1 |
| Doi, SQ; Lagranha, C; Puggina, E; Sellitti, DF | 1 |
| De Godoy, M; Li, F; Rattan, S | 1 |
| Binz, T; Brose, N; Matti, U; Nagy, G; Neher, E; Reim, K; Rettig, J; Sørensen, JB | 1 |
| Cerbán, FM; Coso, OA; Stempin, CC; Tanos, TB | 1 |
| Huang, SH; Shen, WJ; Wang, SM; Yeo, HL | 1 |
| Gounko, NV; Gramsbergen, A; IJkema-Paassen, J; Metzger, F; Swinny, JD; van der Want, JJ | 1 |
| Fukui, H; Horio, S; Kawakami, N; Miyoshi, K | 1 |
| Hirano, J; Kubokawa, M; Nakamura, K | 1 |
| Puggina, E; Sellitti, D | 1 |
| Bae, YS; Jang, MJ; Kwak, JY; Lee, MJ; Min, DS; Park, HY; Ryu, SH | 1 |
| Dewey, WL; Javed, RR; Smith, FL; Smith, PA | 1 |
| Ay, I; Tuncer, M | 1 |
| Bourreau, JP; Chan, FL; Chan, YC; He, GW; Huang, Y; Lau, CW; Yao, XQ | 1 |
| Fukasawa, Y; Hou, J; Kidokoro, Y; Kuromi, H; Sakai, T; Ueno, K | 1 |
| Domenici, MR; Martire, A; Pepponi, R; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Carpenter-Hyland, EP; Chandler, LJ; Woodward, JJ | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Fresno, M; Iñiguez, MA; Jimenez, JL; Muñoz-Fernández, MA | 1 |
| Genovese, G; Halperin, J; Luquet, CM; Tresguerres, M | 1 |
| Adams, JM; Forgèt, MA; Sisson, JH; Wyatt, TA | 1 |
| Joe, EH; Jou, I; Min, KJ; Yang, MS | 1 |
| Busse, R; Falck, JR; Fleming, I; Michaelis, UR; Schmidt, R | 1 |
| Cui, Q; Harvey, AR; Hisheh, S; Luo, JM; Park, K | 1 |
| Binder, BR; Kaun, C; Okajima, K; Uchiba, M; Wojta, J | 1 |
| Bulla, J; Florkovicová, I; Hetényi, L; Kotwica, J; Sanislo, P; Schaeffer, HJ; Sirotkin, AV | 1 |
| Ishisaki, A; Kanno, Y; Kozawa, O; Nakajima, K; Numata, O; Tokuda, H; Yoshida, M | 1 |
| Feng, L; Ji, Y; Lu, B; Pang, PT | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Fernandes, JC; Manacu, CA; Martel-Pelletier, J; Mitrovic, DR; Moldovan, F; Pelletier, JP; Roy-Beaudry, M; Shipkolye, FS | 1 |
| Inoue, K; Koizumi, S; Nasu-Tada, K | 1 |
| Chang, YC; Chen, IM; Chen, YH; Lin, CH; Lin, PJ; Lin, PL; Lu, KL; Tsai, MC | 1 |
| Grossmann, R; Sirotkin, AV | 1 |
| Chen, CT; Chen, IM; Chen, YH; Lin, CH; Lin, MS; Lin, PL; Liu, MC; Tsai, MC | 1 |
| Cox, CL; Govindaiah, G | 1 |
| Ay, B; Iyanoye, A; Pabelick, CM; Prakash, YS; Sieck, GC | 1 |
| Ferrante, RJ; Impey, S; Lee, J; Ratan, RR; Ryu, H | 1 |
| Chou, PH; Hsu, KS; Huang, CC; Yang, CH | 1 |
| Brennan, P; Clement, M; Lam, EW; McLaren, J; Shore, AM; Soeiro, I; White, PC | 1 |
| Espinoza-Fonseca, LM; Trujillo-Ferrara, JG | 1 |
| Baines, DL; Woollhead, AM | 1 |
| Cook, RT; Davies, AJ; Plows, LD; Walker, AJ | 1 |
| Earm, YE; Han, J; Kim, E; Kim, N; Kim, SJ; Park, WS; Son, YK; Warda, M; Youm, JB | 1 |
| Kennedy, TE; Moore, SW | 1 |
| Galski, H; Lazarovici, P; Nagler, A; Sivan, H | 1 |
| Puthenveedu, MA; von Zastrow, M; Yudowski, GA | 1 |
| Abel, T; Isiegas, C; Nguyen, PV; Young, JZ | 1 |
| Kang, SK; Kim, CH; Kim, YH; Park, YG | 1 |
| Mahadevan, D | 1 |
| Harada, N; Isobe, H; Okajima, K; Uchiba, M | 1 |
| Bost, PE; Cayla, X; Dessauge, F; Garcia, A; Guergnon, J; Langsley, G; Rebollo, A; Traincard, F | 1 |
| Hantash, BM; Reeves, JP; Thomas, AP | 1 |
| Bertone, C; Petricca, S; Rossi, F; Santiemma, V | 1 |
| Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ | 1 |
| Asai, N; Costantini, F; Enomoto, A; Fukuda, T; Pachnis, V; Takahashi, M; Wu, Z | 1 |
| Hsu, KS; Huang, CC; Lin, HJ | 1 |
| Earm, YE; Han, J; Kang, SH; Kim, E; Kim, N; Ko, EA; Ko, JH; Park, WS; Son, YK; Warda, M; Youm, JB | 1 |
| Dewey, WL; Gabra, BH; Javed, RR; Smith, FL; Smith, PA | 1 |
| Carpenter, DO; Sukocheva, OA | 1 |
| Brackenbury, WJ; Djamgoz, MB | 1 |
| Chen, YH; Tsai, MC | 1 |
| Chaudhuri, A; Gorelick, FS; Grant, WM; Husain, SZ; Kolodecik, TR | 1 |
| Abbruzzese, A; Budillon, A; Caraglia, M; Chiosi, E; Illiano, G; Improta, S; Marra, M; Naviglio, S; Romano, M; Sorrentino, A; Spina, A | 1 |
| Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M | 1 |
| Ahn, Y; Hogaboam, C; Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, L; Rennard, SI; Sugiura, H; Toews, ML; Togo, S; Wang, X | 1 |
| Das, AK; Dev, S; Fujimoto, K; Fukui, H; Horio, S; Kitamura, Y; Mishima, R; Mizuguchi, H; Takeda, N; Wakayama, Y; Yoshimura, S | 1 |
| De Ruiter, MM; De Zeeuw, CI; Hansel, C; Schmolesky, MT | 1 |
| Ciarmatori, S; Haarmann, A; Huegel, U; Kiepe, D; Tönshoff, B | 1 |
| Fleischmann, BK; Hescheler, J; Reppel, M; Reuter, H; Sasse, P; Schunkert, H | 1 |
| Earm, YE; Han, J; Jung, ID; Kang, SH; Kim, N; Ko, JH; Park, WS; Park, YM; Son, YK; Warda, M | 1 |
| Seidler, U; Tuo, BG; Wen, GR | 1 |
| Asano, M; Harada, N; Mishima, A; Nakayama, T; Nomura, N; Okajima, K; Saito, T | 1 |
| Amsellem, R; Beau, I; Cotte-Laffitte, J; Servin, AL | 1 |
| Choi, S; Lim, I; Roh, S | 1 |
| Caruso-Neves, C; Einicker-Lamas, M; Masuda, CA; Nascimento, MT; Oliveira, MM | 1 |
| Bakiri, Y; Lafourcade, M; Manzoni, OJ; Mato, S; Robbe, D | 1 |
| Kim, YS; Lee, J; Park, D | 1 |
| Chapman, J; Gaus, K; Guo, DL; Hill, M; Huby, T; Jary, E; Jessup, W; Kay, J; Kockx, M; Kritharides, L; Lesnik, P; Sabaretnam, T; Stow, JL | 1 |
| Canalli, AA; Conran, N; Costa, FF; Franco-Penteado, CF; Saad, ST; Traina, F | 1 |
| Jia, Z; Soodvilai, S; Yang, T | 1 |
| Almeida, CB; Conran, N; Costa, FF; Ferreira, RP; Lanaro, C; Saad, ST; Traina, F | 1 |
| Chang, YC; Chen, YH; Chou, HN; Lee, YL; Lin, PL; Lu, KL; Tsai, MC | 1 |
| Ahmadiani, A; Esmaeili-Mahani, S; Javan, M; Koibuchi, N; Maghsoudi, N; Motamedi, F; Shimokawa, N | 1 |
| Lu, CC; Tsai, SC | 1 |
| Arai, M; Harada, N; Katsuya, H; Komura, H; Mizuochi, Y; Okajima, K; Uchiba, M | 1 |
| Chilcoat, CD; Jones, SL; Sharief, Y | 1 |
| Bezerra, CN; Carraro-Lacroix, LR; Girardi, AC; Rebouças, NA | 1 |
| Kloc, R; Luchowska, E; Owe-Larsson, B; Urbanska, EM; Wielosz, M | 1 |
| Searl, TJ; Silinsky, EM | 1 |
| Hattori, N; Inagaki, C; Liu, B; Nakayama, Y; Yang, L | 1 |
| Ito, Y; Kashimoto, R; Kurimoto, T; Mimura, O; Miyoshi, T; Okamoto, N; Oono, S; Tagami, Y | 1 |
| Tattersall, AL; Wilkins, RJ | 1 |
| Bahr, BA; Pin, SS | 1 |
| Chung, J; Huang, SK; Peters-Golden, M; Wettlaufer, SH | 1 |
| Argaw, A; Boire, D; Bouchard, JF; Duff, G; Ptito, M | 1 |
| Ahn, Y; Holz, O; Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Magnussen, H; Mao, L; Rennard, SI; Sato, T; Sugiura, H; Togo, S; Wang, X | 1 |
| Abel, T; Gelinas, JN; Lemon, N; Nguyen, PV; Tenorio, G | 1 |
| Fujimoto, K; Fukui, H; Horio, S; Kawakami, N; Miyoshi, K; Umehara, H | 1 |
| Catalano, M; Cipriani, R; Eusebi, F; Lauro, C; Limatola, C; Sobrero, F; Trettel, F | 1 |
| Banko, JL; Gelinas, JN; Klann, E; Nguyen, PV; Peters, MM; Weeber, EJ | 1 |
| Lee, CH; Liou, HH; Lu, KL; Shen, YC; Tsai, MC | 1 |
| Allen, M; Hall, DD; Hell, JW; Lim, IA; Lu, Y; McKnight, GS; Medvedeva, Y; Usachev, YM; Zhang, M | 1 |
| Adwanikar, H; Fu, Y; Han, J; Ishola, T; Neugebauer, V; Ramsey, C; Scerbo, M | 1 |
| Alkhalaf, M; El-Mowafy, AM; Nassar, NN | 1 |
| Bertone, C; Bianco, MJ; Brama, M; Castelli, A; Rossi, F; Santiemma, V | 1 |
| Akaike, A; Izumi, Y; Kaneko, S; Katsuki, H; Kawato, Y; Kume, T; Nakagawa, T; Niidome, T; Osakada, F; Takada-Takatori, Y | 1 |
| Cai, CY; Cai, ZX; Gu, XY; Guo, HS; Qi, QH; Shan, LJ; Wang, YX; Yin, XZ | 1 |
| Tanaka, M; Watanabe, Y; Yoshimoto, K | 1 |
| Afif, H; Benderdour, M; Chabane, N; Duval, N; Fahmi, H; Martel-Pelletier, J; Mfuna-Endam, L; Motiani, RK; Pelletier, JP; Trebak, M; Zayed, N | 1 |
| Frick, A; Johnston, D; Rosenkranz, JA | 1 |
| Leite, LD; Menegaz, D; Rosso, A; Royer, C; Santos, AR; Silva, FR | 1 |
| Akaike, A; Ito, R; Izumi, Y; Katsuki, H; Kume, T; Niidome, T; Sugimoto, H; Taguchi, R; Takada-Takatori, Y | 1 |
| Cai, JB; Cao, KJ; Huang, YZ; Wang, S; Xu, DJ; Zou, JG | 1 |
| Cai, ZX; Gu, XY; Guo, HS; Li, J; Wu, TH; Yuan, H | 1 |
| Fink, DJ; Mata, M; Peng, X; Zhou, Z | 1 |
| Datta, S; Huang, MP; Siwek, DF | 1 |
| Kloc, R; Luchowska, E; Olajossy, B; Owe-Larsson, B; Urbanska, EM; Wielosz, M; Wnuk, S | 1 |
| Bhattacharjee, A; Nuwer, MO; Picchione, KE | 1 |
| Abbruzzese, A; Caraglia, M; Chiosi, E; Di Gesto, D; Illiano, F; Illiano, G; Marra, M; Naviglio, S; Romano, M; Sorrentino, A; Sorvillo, L; Spina, A | 1 |
| Cho, KW; Choi, DH; Choi, HR; Cui, HZ; Kang, DG; Lee, HS | 1 |
| Chung, KC; Kim, SS; Seo, SR | 1 |
| Chang, YC; Chen, YH; Lu, GL; Tsai, CL; Tsai, MC | 1 |
| Chen, SY; Han, G; Jose, P; Natarajan, A; White, R; Yu, P | 1 |
| Chioni, AM; Djamgoz, MB; Grose, R; Shao, D | 1 |
| Ikeda, T; Ishii, H; Kojima, Y; Masuda, Y; Sugimoto, K; Takada, K | 1 |
| Davis, JP; Kohr, MJ; Roof, SR; Traynham, CJ; Ziolo, MT | 1 |
| Harada, N; Kurihara, H; Nakagata, N; Okajima, K; Zhao, J | 2 |
| Chiosi, E; Di Gesto, D; Giordano, A; Illiano, F; Illiano, G; Naviglio, S; Spina, A | 1 |
| Ikeda, H; Kiritoshi, T; Murase, K | 1 |
| Chen, C; Ma, Y; Sun, Q; Zang, WJ; Zhang, L; Zhao, YF | 1 |
| Makarevich, AV; Rafay, J; Sirotkin, AV | 1 |
| CHEN, YH; HSIEH, CL; HSU, HY; HUANG, SS; LIN, JG; LIN, PL; LU, DY; WU, YT; YANG, HY | 1 |
| Abraham, WC; Connor, SA; Guévremont, D; Nguyen, PV; O'Dell, TJ; Tenorio, G; Williams, J | 1 |
| Chen, Z; Jin, H; Lei, Y; Luo, H; Su, C; Wang, T; Zhong, B; Zhuang, M; Zou, J | 1 |
| Archontis, G; Bischler, N; Hayes, JM; Lamprakis, C; Oikonomakos, NG; Sarrou, J; Skaltsounis, AL; Skamnaki, VT; Zographos, SE | 1 |
| Cristalli, G; Di Angelantonio, S; Grassi, F; Limatola, C; Moriconi, C; Piccioni, A; Trettel, F | 1 |
| Chang, Y; Lin, YW; Wang, SJ | 1 |
| Arita, J; Iguchi, H; Ishida, M; Kanba, S; Mitsui, T | 1 |
| Kiyokage, E; Kurokawa, K; Mizuno, K; Ohkuma, S; Shibasaki, M; Toida, K | 1 |
| Chen, Y; Wang, ZJ; Yang, C | 1 |
| Kurokawa, K; Mizuno, K; Ohkuma, S; Shibasaki, M | 1 |
| Aritake, K; Hori, M; Matsuoka, T; Michishita, M; Murata, T; Narumiya, S; Ozaki, H; Tajima, T; Urade, Y | 1 |
| Brighton, CH; Ott, SR; Quah, PS; Rogers, SM; Vanden Broeck, J; Verdonck, R; Verlinden, H; Vleugels, RK | 1 |
| Berson, DM; Van Hook, MJ; Wong, KY | 1 |
| Feng, Y; Hirasawa, Y; Nagamatsu, T; Nagao, T; Nishiyama, T | 1 |
| Fan, SS; Fang, KM; Lin, CH; Liu, YY; Tsai, CH; Tzeng, SF | 1 |
| Forbes, EM; Goodhill, GJ; Thompson, AW; Yuan, J | 1 |
| Dai, Y; Kobayashi, K; Kogure, Y; Noguchi, K; Wan, Y; Wang, S; Yamanaka, H; Zhang, W; Zhu, W | 1 |
| Bhattacharjee, R; Billiar, TR; Wang, Y; Xiang, W; Zhang, X | 1 |
| Kurokawa, K; Mizuno, K; Ohkuma, S | 1 |
| Castro, LM; Ferro, ES; Gozzo, FC; Russo, LC | 1 |
| Fisher, MJ; Liu, S; Paganini-Hill, A; Yang, F; Yu, C | 1 |
| Pabelick, CM; Prakash, YS; Sathish, V; Thompson, MA; Townsend, EA | 1 |
| Alchini, R; Charron, F; Colman, DR; Farmer, WT; Fournier, AE; Kent, CB; Lepelletier, L; Morin, S; Tessier-Lavigne, M; Yam, PT | 1 |
| Blandin, E; Brette, F; Guinamard, R; Sallé, L; Simard, C | 1 |
| Harraz, OF; Welsh, DG | 1 |
| Cheng, Q; Zhou, Y | 1 |
| Cinalli, AR; Fernandez, V; Guarracino, JF; Losavio, AS; Roquel, LI | 1 |
| Hoffman, MS; Mitchell, GS | 1 |
| Andoh, Y; Fukunaga, K; Hiwasa, T; Ishihara, A; Iwase, K; Kato, M; Matsumoto, E; Muller, D; Seki, N; Takiguchi, M; Yoshimura, S | 1 |
| Bougnoux, P; Chantôme, A; Chevalier, S; Clarysse, L; Guéguinou, M; Potier-Cartereau, M; Vandecasteele, G; Vandier, C | 1 |
| Escobar, ML; Rodríguez-Durán, LF | 1 |
| Cheung, KH; Cheung, MP; Liao, SB; O, WS; Tang, F; Wong, PF | 1 |
| Almami, I; Bonner, PL; Dickenson, JM; Hargreaves, AJ | 1 |
| Cheung, KH; Liao, SB; O, WS; Tang, F | 1 |
| Bray, JK; Chiu, GS; Darmody, PT; Freund, GG; Kwakwa, KA; McCusker, RH; Moon, ML; Walsh, JP | 1 |
| Lee, CH; Liou, HH | 1 |
| Campos, CA; Ritter, RC; Shiina, H | 1 |
| Deng, Z; Lubinski, AJ; Page, TL | 1 |
| Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS | 1 |
| Cheng, SY; Feng, H; Gao, WQ; Hou, Y; Hu, B; James, CD; Li, Y; Li, Z; Parsa, AT; Raizer, JJ; Sarkaria, JN; Xie, B; Yin, Y; Zhang, L; Zhang, W | 1 |
| Chen, Y; Hou, X; Qian, Z; Wang, Y; Yuan, J; Zhang, X; Zou, J | 1 |
| Brignell, JL; Challiss, RA; Davies, NW; Nelson, CP; Perry, MD; Willets, JM | 1 |
| El-Zohairy, SN; Ezeamuzie, CI; Oriowo, MA | 1 |
| Hernández-Cascales, J; Merino, B; Quesada, I | 1 |
| Ju, Y; Untereiner, AA; Wang, R; Wu, L | 1 |
| Hu, J; Schacher, S | 1 |
| Chang, W; Jang, DC; Jang, SS; Jin, Y; Kim, SJ; Park, JM; Shim, HG | 1 |
| Hayashi, Y; Liu, X; Morinaga, S; Nakanishi, H; Wu, Z; Yokoyama, T; Zhang, J | 1 |
| Hsieh, PC; Hung, SC; Lin, SP; Wang, YL | 1 |
| Amano, T; Hara, T; Ide, S; Kaneda, K; Kaneko, T; Minami, M; Ohno, A; Takahashi, D; Yoshioka, M | 1 |
| Abbasnejad, M; Esmaeili-Mahani, S; Pasban-Aliabadi, H | 1 |
| Ji, X; Lipsius, SL; Maxwell, JT; Mignery, GA; Pabbidi, MR; Samarel, AM | 1 |
| Bas, M; Delgado, C; Fernández-Velasco, M; Jesús Larriba, M; Manzanares, E; Martín-Nunes, L; Tamayo, M; Val-Blasco, A | 1 |
| Deng, J; Liang, AL; Tang, J; Wang, DX; Xiang, DK | 1 |
| Amar, M; Mallick, BN; Singh, A | 1 |
| Hou, L; Li, Q; Liu, Z; Zhang, G; Zhang, M; Zhang, X; Zhou, X; Zhu, L | 1 |
| Bova, S; Fusi, F; Sgaragli, G; Spiga, O; Trezza, A | 1 |
| Baran, CN; Clason, TA; Girard, BM; Hardwick, JC; May, V; Merriam, LA; Parsons, RL; Tompkins, JD | 1 |
| Apostolopoulos, V; Büsselberg, D; Caprnda, M; Hayes, A; Kruzliak, P; Matsoukas, J; Matsoukas, MT; Qaradakhi, T; Rimarova, K; Rybalka, E; Sepsi, M; Zulli, A | 1 |
| Berry, JN; Prendergast, MA; Reynolds, AR; Saunders, MA; Sharrett-Field, LJ; Winchester, S | 1 |
| Fu, Y; He, YH; Li, Y; Lin, SD; Liu, QC; Long, J; Mu, MY; Yang, FW | 1 |
| Arcella, A; Esposito, V; Fucile, S; Martinello, K; Mascia, A; Morace, R; Sciaccaluga, M | 1 |
| Bae, H; Bang, H; Choi, J; Kim, JH; Kim, T; Kim, YW; Ko, JH; Lee, D; Lim, I | 1 |
| Cerveny, L; Jiraskova, L; Karbanova, S; Ptackova, Z; Staud, F | 1 |
| Bae, H; Kim, T; Lim, I | 1 |
1 review(s) available for pyrroles and kt 5720
| Article | Year |
|---|---|
Multiple allosteric sites on muscarinic receptors.
Topics: Allosteric Site; Carbazoles; Enzyme Inhibitors; Indoles; Ligands; Molecular Structure; Mutagenesis, Site-Directed; Protein Binding; Pyrroles; Receptors, Muscarinic; Staurosporine | 2001 |
1 trial(s) available for pyrroles and kt 5720
| Article | Year |
|---|---|
Estrogen effects on human airway smooth muscle involve cAMP and protein kinase A.
Topics: Adrenergic beta-Agonists; Asthma; Bronchoconstriction; Calcium Signaling; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Estrogens; Female; Humans; Isoproterenol; Myocytes, Smooth Muscle; Pyrroles; Receptors, Adrenergic, beta; Respiratory System | 2012 |
373 other study(ies) available for pyrroles and kt 5720
| Article | Year |
|---|---|
Histamine-induced depolarization and the cyclic AMP--protein kinase A system in isolated guinea pig adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alprostadil; Animals; Carbazoles; Colforsin; Cyclic AMP; Electrophysiology; Epididymis; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Insulin; Isoproterenol; Male; Membrane Potentials; Protein Kinase C; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1992 |
Histamine-induced differentiation of HL-60 cells. The role of cAMP and protein kinase A.
Topics: Carbazoles; Cell Differentiation; Cell Line; Cimetidine; Cyclic AMP; Enzyme Activation; Histamine; Humans; Indoles; Neutrophils; Peroxidase; Phagocytosis; Phosphorylation; Protein Kinases; Pyrroles; Receptors, Histamine H2 | 1992 |
Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinases; Pyrroles; Quinolones; Thromboxane A2 | 1992 |
Glucocorticoids increase Ca2+ influx through dihydropyridine-sensitive channels linked to activation of protein kinase C in vascular smooth muscle cells.
Topics: Alkaloids; Animals; Aorta; Calcium; Calcium Channels; Carbazoles; Cell Line; Cell Membrane; Cytosol; Dexamethasone; Indoles; Isradipine; Kinetics; Muscle, Smooth, Vascular; Protein Kinase C; Pyrroles; Rats; Staurosporine | 1992 |
Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. II. Interaction between phorbol ester- and cAMP-sensitive pathways.
Topics: Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Cell Aggregation; Cells, Cultured; Cyclic AMP; Humans; Indoles; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Lymphocyte Function-Associated Antigen-1; Lymphocytes; Protein Kinase C; Protein Kinases; Pyrroles; Tetradecanoylphorbol Acetate | 1992 |
The protein kinase C inhibitor, calphostin C, inhibits succinate-dependent mitochondrial reduction of MTT by a mechanism that does not involve protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow; Carbazoles; Cell Division; Cell Line; Coloring Agents; DNA Replication; Indoles; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Mitochondria; Naphthalenes; Oxidation-Reduction; Piperazines; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Succinates; Tetrazolium Salts; Thiazoles; Thymidine | 1992 |
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.
Topics: Alkaloids; Carbazoles; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Humans; In Vitro Techniques; Indole Alkaloids; Indoles; Interphase; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine | 1992 |
[Intracellular actions of antiplatelet drugs which affect cyclic AMP metabolism in platelets--their effects on Ca2+ mobilization and protein phosphorylation in human platelets].
Topics: Alprostadil; Blood Platelets; Calcium; Carbazoles; Colforsin; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Pyrroles; Thromboxane A2 | 1990 |
Staurosporine, a novel protein kinase C inhibitor, prevents postischemic neuronal damage in the gerbil and rat.
Topics: Alkaloids; Animals; Brain Ischemia; Carbazoles; Cell Survival; Gerbillinae; Hippocampus; Indoles; Male; Neurons; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Inbred WF; Staurosporine; Sulfonamides | 1990 |
Induction of differentiation of HL-60 cells by protein kinase C inhibitor, K252a.
Topics: Carbazoles; Cell Differentiation; Cell Division; DNA, Neoplasm; Humans; Indole Alkaloids; Indoles; Leukemia, Promyelocytic, Acute; Protein Kinase C; Protein Kinases; Pyrroles; Tumor Cells, Cultured | 1990 |
Effect of concanavalin A on serotonin transport into blood platelets: possible involvement of protein kinase C.
Topics: Alkaloids; Animals; Biological Transport, Active; Blood Platelets; Blood Proteins; Calcium; Calcium Radioisotopes; Carbazoles; Concanavalin A; In Vitro Techniques; Indole Alkaloids; Indoles; Lanthanum; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rabbits; Serotonin; Staurosporine | 1990 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
Forskolin potentiates G-CSF-induced proliferation of a murine myeloblastic leukemia cell line.
Topics: Animals; Carbazoles; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Indoles; Interleukin-3; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred DBA; Pyrroles; Signal Transduction; Tumor Cells, Cultured | 1994 |
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine | 1993 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Species and age-dependent differences of functional coupling between opioid delta-receptor and G-proteins and possible involvement of protein kinase C in striatal membranes.
Topics: Aging; Analgesics; Animals; Carbazoles; Cell Membrane; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Guinea Pigs; Indoles; Kinetics; Male; Naltrexone; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Species Specificity | 1994 |
Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation.
Topics: 1-Methyl-3-isobutylxanthine; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Benzeneacetamides; Bucladesine; Carbazoles; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; DNA Replication; Flavanones; Flavonoids; Glomerular Mesangium; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; Indoles; Indomethacin; Lipoxygenase Inhibitors; Male; Platelet-Derived Growth Factor; Pyrroles; Rats; Rats, Sprague-Dawley; Umbelliferones | 1994 |
Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.
Topics: Adult; Alkaloids; Analog-Digital Conversion; Biological Transport; Bucladesine; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Erythroid Precursor Cells; Erythropoietin; Genistein; Humans; Image Processing, Computer-Assisted; Indoles; Intercellular Signaling Peptides and Proteins; Intracellular Fluid; Isoflavones; Isoquinolines; Naphthalenes; Peptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Videotape Recording; Wasp Venoms | 1994 |
The activation of protein kinase A pathway selectively inhibits anterograde axonal transport of vesicles but not mitochondria transport or retrograde transport in vivo.
Topics: Adenosine Triphosphate; Animals; Astacoidea; Axonal Transport; Axons; Bucladesine; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Kinesins; Kinetics; Macromolecular Substances; Mitochondria; Organelles; Peptide Mapping; Phosphorylation; Pyrroles; Time Factors | 1995 |
Phosphorylation and adrenergic chronotropism and inotropism in guinea pig cardiac muscles.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic Agents; Adrenergic beta-Agonists; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Epinephrine; Ethers, Cyclic; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Indoles; Kinetics; Male; Myocardial Contraction; Myocardium; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Pyrroles; Receptors, Adrenergic, beta-1 | 1995 |
VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cell Cycle; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Glucagon; Histamine; Histamine Antagonists; Humans; Indoles; Kinetics; Muscle, Smooth; Pyrroles; Thymidine; Trachea; Vasoactive Intestinal Peptide | 1995 |
Effects of insulin, insulin-like growth factor-I, and phorbol esters on neutral cholesteryl esterase activity in cultured rat vascular smooth muscle cells.
Topics: Alkaloids; Animals; Aorta; Carbazoles; Cells, Cultured; Cyclic AMP; Indoles; Insulin; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; Phenylurea Compounds; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Staurosporine; Sterol Esterase; Sterol O-Acyltransferase; Tetradecanoylphorbol Acetate | 1995 |
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cells, Cultured; Dendrites; Female; Hippocampus; Imidazoles; Indoles; Isoquinolines; Naphthalenes; Neurites; Piperazines; Polycyclic Compounds; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Pyramidal Tracts; Pyrroles; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Identification of a 170 kDa membrane kinase with increased activity in KB-V1 multidrug resistant cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Calcium; Carbazoles; Carrier Proteins; Clone Cells; Cyclic AMP; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Indole Alkaloids; Indoles; KB Cells; Melanoma, Experimental; Membrane Glycoproteins; Mice; Neoplasm Proteins; Phosphatidylserines; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyrroles; Staurosporine; Transfection; Tumor Cells, Cultured; Tyrosine | 1993 |
Inhibition of protein kinase A fails to alter mast cell adenosine responsiveness.
Topics: Adenosine; Adenylyl Cyclases; Animals; Bone Marrow Cells; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Mast Cells; Mice; Mice, Inbred BALB C; Pyrroles; Receptors, Purinergic P1; Type C Phospholipases | 1994 |
KT-5720 reverses multidrug resistance in variant S49 mouse lymphoma cells transduced with the human MDR1 cDNA and in human multidrug-resistant carcinoma cells.
Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Southern; Carbazoles; Carcinoma; DNA, Complementary; Drug Resistance, Multiple; Humans; Indoles; Lymphoma; Mice; Protein Kinase C; Pyrroles; Transduction, Genetic; Tumor Cells, Cultured | 1995 |
Activation of adenylate cyclase attenuates the hyperpolarization following single action potentials in brain noradrenergic neurons independently of protein kinase A.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenylyl Cyclases; Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Indoles; Isoquinolines; Locus Coeruleus; Neurons; Norepinephrine; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Staurosporine; Thionucleotides | 1994 |
Regulation of motility and cytoskeletal organization of rat bladder carcinoma cells by cyclic AMP.
Topics: Actinin; Actins; Animals; Bucladesine; Carbazoles; Cell Membrane; Cell Movement; Cholera Toxin; Cyclic AMP; Cytoskeleton; Indoles; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rats; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Virulence Factors, Bordetella | 1994 |
Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase.
Topics: Alkaloids; Amiloride; Animals; Atrial Natriuretic Factor; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Kidney Medulla; Male; Nitric Oxide; Ouabain; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase | 1995 |
Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP.
Topics: Animals; Calcium; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Models, Biological; Nerve Fibers; Presynaptic Terminals; Pyramidal Cells; Pyrroles; Sulfonamides; Synaptic Transmission | 1994 |
K252a, KT5720, KT5926, and U98017 support paclitaxel (taxol)-dependent cells and synergize with paclitaxel.
Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbazoles; Cell Division; Cell Line; CHO Cells; Cricetinae; Drug Synergism; Indole Alkaloids; Indoles; Myosin-Light-Chain Kinase; Paclitaxel; Pyrroles; Staurosporine | 1994 |
Angiopeptin, the octapeptide analogue of somatostatin, decreases rat heart endothelial cell adhesiveness for mononuclear cells.
Topics: Amino Acid Sequence; Animals; Bucladesine; Carbazoles; Cell Adhesion; Cell Line; Endothelium, Vascular; Flow Cytometry; Heart; Indoles; Leukocytes, Mononuclear; Molecular Sequence Data; Oligopeptides; Peptides, Cyclic; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Somatostatin | 1993 |
Histamine-induced production of interleukin-1 alpha from murine bone marrow stromal cells and its inhibition by H2 blockers.
Topics: Animals; Blotting, Western; Bone Marrow; Bone Marrow Cells; Carbazoles; Cells, Cultured; Colony-Forming Units Assay; Cyclic AMP; Granulocytes; Histamine; Histamine H2 Antagonists; Indoles; Interleukin-1; Male; Methylhistamines; Mice; Mice, Inbred BALB C; Protein Kinase C; Protein Precursors; Pyrroles; Stromal Cells; T-Lymphocytes | 1993 |
Vasoactive intestinal peptide and forskolin stimulate interleukin 6 production by rat cortical astrocytes in culture via a cyclic AMP-dependent, prostaglandin-independent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Bucladesine; Carbazoles; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; Indoles; Interleukin-6; Prostaglandins; Pyrroles; Radioimmunoassay; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1994 |
Effect of protein kinase inhibitors on IL-8/NAP-1 release from human umbilical vein endothelial cells.
Topics: Alkaloids; Benzoquinones; Carbazoles; Cells, Cultured; Endothelium, Vascular; Humans; Indoles; Interleukin-1; Interleukin-8; Lactams, Macrocyclic; Protein Kinase Inhibitors; Pyrroles; Quinones; Recombinant Proteins; Rifabutin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation.
Topics: Animals; Carbazoles; Electric Stimulation; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Male; Neuronal Plasticity; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Synapses | 1993 |
The effect of polyamines on voltage-activated calcium channels in mouse neuroblastoma cells.
Topics: Alkaloids; Animals; Calcium Channels; Carbazoles; Electric Stimulation; Indoles; Membrane Potentials; Mice; Neuroblastoma; Polyamines; Protein Kinase C; Putrescine; Pyrroles; Staurosporine; Tumor Cells, Cultured | 1993 |
Growth regulation of the human papillary thyroid cancer cell line by protein tyrosine kinase and cAMP-dependent protein kinase.
Topics: Adult; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystadenoma, Papillary; Enzyme Inhibitors; Female; Growth Substances; Humans; Indoles; Protein-Tyrosine Kinases; Pyrroles; Thyroid Neoplasms; Thyrotropin; Tumor Cells, Cultured | 1994 |
Regulation of human Caco-2 intestinal epithelial brush border enzyme activity by cyclic nucleotides.
Topics: Adenylyl Cyclase Inhibitors; Alkaline Phosphatase; Alkaloids; Bucladesine; Caco-2 Cells; Carbazoles; Cell Line; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Synergism; Enzyme Inhibitors; Epithelium; Guanylate Cyclase; Homeostasis; Humans; Indoles; Intestines; Kinetics; Microvilli; Pyrroles | 1996 |
Cholera toxin enhances taurine uptake in cultures of human retinal pigment epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Carrier Proteins; Cell Line; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Phosphodiesterase Inhibitors; Pigment Epithelium of Eye; Pyrroles; Taurine | 1996 |
Adenosine A2 receptor occupancy regulates stimulated neutrophil function via activation of a serine/threonine protein phosphatase.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Carbazoles; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Humans; In Vitro Techniques; Indoles; Kinetics; Marine Toxins; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Purinergic P1 Receptor Agonists; Pyrroles; Superoxides | 1996 |
Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Nitroprusside; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thionucleotides; Time Factors | 1996 |
The specific type IV phosphodiesterase inhibitor rolipram combined with adenosine reduces tumor necrosis factor-alpha-primed neutrophil oxidative activity.
Topics: Adenosine; Carbazoles; Drug Synergism; Humans; In Vitro Techniques; Indoles; Neutrophils; Pentoxifylline; Phenethylamines; Phosphodiesterase Inhibitors; Pyrroles; Pyrrolidinones; Respiratory Burst; Rolipram; Superoxides; Tumor Necrosis Factor-alpha | 1995 |
Signal transduction mechanism responsible for changes in axoplasmic transport caused by neurotransmitters.
Topics: Acetylcholine; Animals; Axonal Transport; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epinephrine; GTP-Binding Proteins; Indoles; Mice; Mice, Inbred C57BL; Microscopy, Video; Models, Neurological; Neurons; Neurotransmitter Agents; Phosphorylation; Pyrroles; Receptor, Muscarinic M2; Receptors, Adrenergic, beta-2; Receptors, Muscarinic; Signal Transduction; Superior Cervical Ganglion | 1996 |
Protein kinase A activation is required for IL-1-induced nitric oxide production by cardiac myocytes.
Topics: Animals; Base Sequence; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Indoles; Interleukin-1; Molecular Probes; Molecular Sequence Data; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Pyrroles; Rats; RNA, Messenger | 1996 |
Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Chickens; Cochlea; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Indoles; Isoquinolines; Organ Culture Techniques; Pyrroles; Regeneration; Signal Transduction; Sulfonamides | 1996 |
Role of protein kinase C in desensitization of spinal delta-opioid-mediated antinociception in the mouse.
Topics: Analgesics; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Leucine; Enzyme Inhibitors; Indoles; Injections, Spinal; Male; Membranes; Mice; Mice, Inbred ICR; Naphthalenes; Oligopeptides; Pain Measurement; Protein Kinase C; Pyrroles; Receptors, Opioid; Receptors, Opioid, delta; Spinal Cord | 1996 |
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: a possible pathway for inhibition of the respiratory burst.
Topics: Bucladesine; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphoproteins; Phosphorylation; Pyrroles; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Signal pathways and ligament cell adhesiveness.
Topics: Adult; Alkaloids; Anterior Cruciate Ligament; Calcimycin; Calcium; Carbazoles; Cell Adhesion; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Female; Fibroblasts; Fibronectins; Glass; Humans; Indoles; Integrins; Ionophores; Male; Medial Collateral Ligament, Knee; Microscopy, Fluorescence; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Signal Transduction | 1996 |
The inhibitory effects of iberiotoxin and 4-aminopyridine on the relaxation induced by beta 1- and beta 2-adrenoceptor activation in rat aortic rings.
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Aorta, Thoracic; Atenolol; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Imines; Indoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Peptides; Propanolamines; Pyrroles; Rats; Scorpion Venoms | 1996 |
Potentiation by thyroxine of interferon-gamma-induced antiviral state requires PKA and PKC activities.
Topics: Animals; Calmodulin; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; HeLa Cells; Humans; Indoles; Interferon-gamma; L Cells; Mice; Protein Kinase C; Pyrroles; Pyrrolidinones; Rhabdoviridae Infections; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thyroxine; Time Factors; Vesicular stomatitis Indiana virus; Viral Interference | 1996 |
Mechanism of activation by cGMP-dependent protein kinase of large Ca(2+)-activated K+ channels in mesangial cells.
Topics: Adenosine Triphosphate; Alkaloids; Calcium; Carbazoles; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Humans; Indoles; Kinetics; Membrane Potentials; Okadaic Acid; Patch-Clamp Techniques; Potassium Channels; Protein Kinase Inhibitors; Pyrroles; Staurosporine | 1996 |
Temporal activation of Ca2+-calmodulin-sensitive protein kinase type II is obligate for adipogenesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Adipose Tissue; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Indoles; Mice; Pyrroles; Sulfonamides | 1997 |
Effects of spinal versus supraspinal administration of cyclic nucleotide-dependent protein kinase inhibitors on morphine tolerance in mice.
Topics: Alkaloids; Animals; Brain; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Indoles; Injections, Intraventricular; Injections, Subcutaneous; Mice; Mice, Inbred ICR; Morphine Dependence; Pain Threshold; Pyrroles; Spinal Cord; Up-Regulation | 1997 |
PKC phosphorylation disrupts gap junctional communication at G0/S phase in clone 9 cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Communication; Cells, Cultured; Clone Cells; Connexin 43; Enzyme Inhibitors; Fluorescent Dyes; Gap Junctions; Imidazoles; Indoles; Liver; Naphthalenes; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Resting Phase, Cell Cycle; S Phase; Transcription, Genetic | 1997 |
Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; G1 Phase; Gene Expression; Indoles; Microtubule-Associated Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Pyrroles; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
Characterization of the prostanoid receptors mediating inhibition of PAF-induced aggregation of guinea-pig eosinophils.
Topics: Alprostadil; Analysis of Variance; Animals; Anti-Ulcer Agents; Carbazoles; Cell Aggregation; Dinoprostone; Dose-Response Relationship, Drug; Eosinophils; Female; Guinea Pigs; Indoles; Misoprostol; Oxytocics; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandins E, Synthetic; Prostanoic Acids; Protein Kinase C; Pyrroles; Receptors, Prostaglandin; Structure-Activity Relationship | 1997 |
Modulation of inwardly rectifying ATP-regulated K+ channel by phosphorylation process in opossum kidney cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Animals; Bucladesine; Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indole Alkaloids; Indoles; Kidney; Opossums; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Potassium Channels; Protein Kinase Inhibitors; Pyrroles | 1997 |
Involvement of intracellular cyclic GMP and cyclic GMP-dependent protein kinase in alpha-elastin-induced macrophage chemotaxis.
Topics: Alkaloids; Animals; Carbazoles; Cells, Cultured; Chemotaxis; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Elastin; Enzyme Inhibitors; Indoles; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
The role of cAMP- and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan.
Topics: Alkaloids; Animals; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Guinea Pigs; Hydrazones; In Vitro Techniques; Indoles; Milrinone; Myocardial Contraction; Myocardium; Papillary Muscles; Perfusion; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Pyridazines; Pyridones; Pyrroles; Simendan; Stimulation, Chemical | 1997 |
The mechanisms of compound 48/80-induced superoxide generation mediated by A-kinase in rat peritoneal mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Bucladesine; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Granulomatous Disease, Chronic; Immunohistochemistry; Indoles; Isoproterenol; Male; Mast Cells; NADPH Oxidases; p-Methoxy-N-methylphenethylamine; Phosphoproteins; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Terpenes | 1997 |
Systemic administration of ACTH or vasopressin reverses the amnestic effect of posttraining beta-endorphin or electroconvulsive shock but not that of intrahippocampal infusion of protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arousal; beta-Endorphin; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cosyntropin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fear; Hippocampus; Indoles; Injections, Intraperitoneal; Lypressin; Male; Mental Recall; Neural Pathways; Pyrroles; Rats; Rats, Wistar; Retention, Psychology | 1997 |
Alpha-1A adrenergic receptor stimulation with phenylephrine promotes arachidonic acid release by activation of phospholipase D in rat-1 fibroblasts: inhibition by protein kinase A.
Topics: Adenine; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Calcimycin; Carbazoles; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Glycerides; GTP-Binding Proteins; Indoles; Lipase; Phenylephrine; Phospholipase D; Phospholipases A; Phospholipases A2; Prazosin; Pyrroles; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Transfection; Virulence Factors, Bordetella | 1998 |
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Epoprostenol; Indoles; Inositol 1,4,5-Trisphosphate; Megakaryocytes; Platelet Aggregation Inhibitors; Pyrroles; Rats; Rats, Wistar | 1998 |
Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes.
Topics: Androstadienes; Animals; Apoptosis; Bile Acids and Salts; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Solubility; Wortmannin | 1998 |
Signaling through the B cell antigen receptor regulates discrete steps in the antigen processing pathway.
Topics: Alkaloids; Animals; Antigen Presentation; Benzophenanthridines; Carbazoles; Genistein; Histocompatibility Antigens Class II; Indoles; Mice; Phenanthridines; Protein Kinases; Pyrroles; Rabbits; Receptors, Antigen, B-Cell | 1998 |
Mucin-like glycoprotein secretion is mediated by cyclic-AMP and protein kinase C signal transduction pathways in rat corneal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium, Corneal; Indoles; Male; Mucins; Naphthalenes; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Distinct differences between morphine- and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin-mu-opioid receptor complexes demonstrated by cyclic AMP-dependent protein kinase phosphorylation.
Topics: Analgesics, Opioid; Antibody Specificity; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Enzyme Inhibitors; Indoles; Morphine; Neuroblastoma; Neurons; Phosphorylation; Precipitin Tests; Pyrroles; Receptors, Opioid, mu; Tumor Cells, Cultured | 1998 |
Regulation of interleukin-6 production by prostaglandin E2 in fetal rat osteoblasts: role of protein kinase A signaling pathway.
Topics: Animals; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Indoles; Interleukin-6; Isoquinolines; Osteoblasts; Promoter Regions, Genetic; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thionucleotides; Transcription, Genetic | 1998 |
Atrial natriuretic peptide enhances IL-1 beta-stimulated nitric oxide production in cultured rat vascular smooth muscle cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Blotting, Northern; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Indoles; Interleukin-1; Intracellular Fluid; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger | 1998 |
Na+-K+-2Cl- cotransport in Ehrlich cells: regulation by protein phosphatases and kinases.
Topics: Animals; Azepines; Bradykinin; Carbazoles; Carcinoma, Ehrlich Tumor; Carrier Proteins; Chlorides; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Homeostasis; Hypertonic Solutions; Indoles; Isoquinolines; Kinetics; Marine Toxins; Mice; Myosin-Light-Chain Kinase; Naphthalenes; Osmolar Concentration; Oxazoles; Phosphoprotein Phosphatases; Potassium; Protein Kinases; Pyrroles; Sodium-Potassium-Chloride Symporters; Sulfonamides; Tumor Cells, Cultured | 1998 |
KT5720 and U-98017 inhibit MAPK and alter the cytoskeleton and cell morphology.
Topics: Animals; Antibodies; Antineoplastic Agents, Phytogenic; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Size; CHO Cells; Cricetinae; Cytoskeleton; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Indoles; Mitogen-Activated Protein Kinase Kinases; Paclitaxel; Protein Kinases; Pyrroles; Staurosporine; Tubulin | 1998 |
Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells.
Topics: Animals; Bronchi; Bucladesine; Carbazoles; Cattle; Chromatography, Ion Exchange; Cilia; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoproterenol; Kinetics; Nitroprusside; Pyrroles; Time Factors | 1998 |
Vasopressin-induced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Antioxidants; Bile Canaliculi; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Indoles; Leupeptins; Liver; Male; Microscopy, Electron, Scanning; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Tight Junctions; Vacuoles; Vasopressins | 1998 |
Protein kinase G expression in the small intestine and functional importance for smooth muscle relaxation.
Topics: Alkaloids; Animals; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Guinea Pigs; Indoles; Intestinal Mucosa; Intestine, Small; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Polymerase Chain Reaction; Pyrroles; Rats; Rats, Wistar; Thionucleotides | 1998 |
Cyclic AMP mediates endothelial protection by nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1998 |
Anti-oxidative effects of theophylline on human neutrophils involve cyclic nucleotides and protein kinase A.
Topics: Alkaloids; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Indoles; Neutrophil Activation; Neutrophils; Oxidative Stress; Phosphodiesterase Inhibitors; Pyrroles; Superoxides; Theophylline | 1998 |
Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytosol; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Pyrroles; Quinolones; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Involvement of mechanisms dependent on NMDA receptors, nitric oxide and protein kinase A in the hippocampus but not in the caudate nucleus in memory.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbazoles; Caudate Nucleus; Cues; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Indoles; Long-Term Potentiation; Male; Maze Learning; Memory; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyrroles; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Late and prolonged post-training memory modulation in entorhinal and parietal cortex by drugs acting on the cAMP/protein kinase A signalling pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Amygdala; Animals; Avoidance Learning; Benzazepines; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine Antagonists; Entorhinal Cortex; Indoles; Male; Memory; Parietal Lobe; Pyrroles; Rats; Rats, Wistar; Signal Transduction | 1997 |
Drugs acting upon the cyclic adenosine monophosphate/protein kinase A signalling pathway modulate memory consolidation when given late after training into rat hippocampus but not amygdala.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Benzazepines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine Antagonists; Hippocampus; Indoles; Male; Memory; Norepinephrine; Piperazines; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Dopamine D1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Time Factors; Timolol | 1997 |
The role of cyclic AMP and protein kinase A in stimulation of neutrophil migration by endothelins.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Carbazoles; Cell Movement; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Endothelin-2; Endothelin-3; Endothelins; Enzyme Inhibitors; Humans; Imines; Indoles; Neutrophils; Pyrroles; Thionucleotides | 1998 |
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine | 1998 |
Activation of inwardly rectifying K+ channel in OK proximal tubule cells involves cGMP-dependent phosphorylation process.
Topics: Alkaloids; Animals; Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytosol; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Indoles; Kidney Tubules, Proximal; Opossums; Patch-Clamp Techniques; Potassium Channels; Protein Kinase Inhibitors; Pyrroles | 1998 |
Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism.
Topics: Animals; Axons; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Myelin Sheath; Myelin-Associated Glycoprotein; Nerve Growth Factors; Nerve Regeneration; Neural Inhibition; Neurons; Pyrroles; Rats | 1999 |
Modulation of the neuronal nicotinic acetylcholine receptor-channel by the nootropic drug nefiracetam.
Topics: Acetylcholine; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Membrane Potentials; Naphthalenes; Neurons; Nootropic Agents; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Protein Kinase C; Pyrroles; Pyrrolidinones; Rats; Receptors, Nicotinic; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Involvement of phosphodiesterase-cGMP-PKG pathway in intracellular Ca2+ oscillations in pituitary GH3 cells.
Topics: Alkaloids; Animals; Calcium; Carbazoles; Cell Line; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 1; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Indoles; Phosphoric Diester Hydrolases; Pituitary Gland; Protein Kinases; Pyrroles; Vinca Alkaloids | 1999 |
Immunomodulatory effects of pharmacological elevation of cyclic AMP in T lymphocytes proceed via a protein kinase A independent mechanism.
Topics: Adjuvants, Immunologic; Carbazoles; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Indoles; Interferon-gamma; Interleukin-2; Isoquinolines; Lymphocyte Activation; Protein Kinase C; Pyrroles; Sulfonamides; T-Lymphocytes; Thionucleotides | 1999 |
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 1999 |
Modification of the expression of naloxone-precipitated withdrawal signs in morphine-dependent mice by diabetes: possible involvement of protein kinase C.
Topics: Animals; Behavior, Animal; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Frontal Lobe; Indoles; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Norepinephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Substance Withdrawal Syndrome | 1999 |
Gating of BDNF-induced synaptic potentiation by cAMP.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cells, Cultured; Cyclic AMP; Cycloleucine; Excitatory Postsynaptic Potentials; Indoles; Nerve Growth Factors; Neuronal Plasticity; Neurons; Neurotrophin 3; Okadaic Acid; Patch-Clamp Techniques; Pyrroles; Signal Transduction; Synapses; Synaptic Transmission; Thionucleotides; Xenopus | 1999 |
Effect of myosin light chain kinase, protein kinase A, and protein kinase C inhibition on porcine oocyte activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Carbazoles; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Enzyme Inhibitors; Exocytosis; Female; Indoles; Microscopy, Electron; Myosin-Light-Chain Kinase; Oocytes; Protein Kinase C; Pyrroles; Swine; Wortmannin | 1999 |
Possible involvement of spinal protein kinase C in thermal allodynia and hyperalgesia in diabetic mice.
Topics: Analysis of Variance; Animals; Capsaicin; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Spinal Cord | 1999 |
Possible mechanisms for insulin-induced attenuation of the antinociceptive effect of [D-Ala2, N-MePhe4, Gly-ol5]enkephalin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics, Opioid; Animals; Benzoquinones; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Hypoglycemic Agents; Indoles; Injections, Intraventricular; Insulin; Lactams, Macrocyclic; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain Measurement; Protein Kinase C; Pyrroles; Quinones; Rifabutin; Time Factors | 1999 |
Intracellular mechanisms involved in dopamine-induced actin cytoskeleton organization and maintenance of a round phenotype in cultured rat lactotrope cells.
Topics: Actins; Animals; Carbazoles; Cell Membrane; Cell Size; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Dopamine; Enzyme Inhibitors; Estrus; Female; Indoles; Kinetics; Nifedipine; Pituitary Gland, Anterior; Prolactin; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Second Messenger Systems | 1999 |
A late phase of cerebellar long-term depression requires activation of CaMKIV and CREB.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Glutamic Acid; Indoles; Long-Term Potentiation; Membrane Potentials; Mice; Neural Inhibition; Patch-Clamp Techniques; Purkinje Cells; Pyrroles; Signal Transduction; Thionucleotides; Transfection | 1999 |
Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Carbazoles; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Macrophage-1 Antigen; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyrroles; Receptors, IgG; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Participation of protein kinases in staurosporine-induced interleukin-6 production by rat peritoneal macrophages.
Topics: Animals; Carbazoles; Chromones; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Indole Alkaloids; Indoles; Interleukin-6; Isoquinolines; Macrophages, Peritoneal; Male; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Time Factors | 1999 |
Atriopeptin, sodium azide and cyclic GMP reduce secretion of aqueous humour and inhibit intracellular calcium release in bovine cultured ciliary epithelium.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Aqueous Humor; Atrial Natriuretic Factor; Calcium; Carbazoles; Cattle; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Indoles; Intraocular Pressure; Pigment Epithelium of Eye; Protein Kinase Inhibitors; Pyrroles; Sodium Azide | 1999 |
Phospholipid signalling pathways in Trypanosoma cruzi growth control.
Topics: Adenylate Cyclase Toxin; Animals; Benzylamines; Carbazoles; Cell Division; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Estrenes; Indoles; Lysophospholipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Protein Kinases; Pyrroles; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides; Trypanosoma cruzi; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: involvement of A3 adenosine receptor.
Topics: Adenosine; Bucladesine; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Indoles; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Oxygen Consumption; Pyrroles; Receptor, Adenosine A3; Receptors, Purinergic P1; Respiratory Burst; RNA, Messenger; Second Messenger Systems; Theobromine; Xanthines | 1999 |
Effects of PKA inhibitors, H-compounds, on epithelial Na+ channels via PKA-independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoquinolines; Myristic Acid; Pulmonary Alveoli; Pyrroles; Rats; Rats, Wistar; Sodium; Sodium Channels; Structure-Activity Relationship; Sulfonamides; Terbutaline | 1999 |
Novelty causes time-dependent retrograde amnesia for one-trial avoidance in rats through NMDA receptor- and CaMKII-dependent mechanisms in the hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Amnesia, Retrograde; Animals; Avoidance Learning; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Environment; Enzyme Inhibitors; Hippocampus; Indoles; Injections; Male; Psychomotor Performance; Pyrroles; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors | 1999 |
Anchoring protein is required for cAMP-dependent stimulation of L-type Ca(2+) channels in rabbit portal vein.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Barium; Calcium Channels, L-Type; Carbazoles; Carrier Proteins; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; Indoles; Isoproterenol; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Portal Vein; Proteins; Pyrroles; Rabbits | 1999 |
Capacitance measurements reveal different pathways for the activation of CFTR.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Enzyme Inhibitors; Female; Indoles; Intracellular Membranes; Isoquinolines; Mutation; Oocytes; Patch-Clamp Techniques; Pyrroles; Reference Values; Thionucleotides; Xenopus laevis | 1999 |
Role of protein kinases A and C in the induction of mGluR-dependent long-term depression in the medial perforant path of the rat dentate gyrus in vitro.
Topics: Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dentate Gyrus; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Maleimides; Neural Inhibition; Perforant Pathway; Protein Kinase C; Pyrroles; Rats; Receptors, Metabotropic Glutamate; Sulfonamides | 1999 |
Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Aorta; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Thionucleotides; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Brain; Carbazoles; Cells, Cultured; Cerebellum; Cyclic AMP; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Hydrogen Sulfide; Imines; Indoles; Neuroglia; Neurons; Oocytes; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus laevis | 2000 |
alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels.
Topics: Adrenergic alpha-Agonists; Aspirin; Blood Platelets; Brimonidine Tartrate; Calcium; Calcium Chloride; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Epinephrine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Models, Biological; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Prostaglandins E; Pyrroles; Quinoxalines; Receptors, Adrenergic, alpha-2; Stimulation, Chemical; Thapsigargin; Thimerosal; Thrombin; Time Factors | 2000 |
beta-Adrenergic agonist modulation of monocyte adhesion to airway epithelial cells in vitro.
Topics: Adrenergic beta-Agonists; Bronchi; Bucladesine; Carbazoles; Cell Adhesion; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Isoproterenol; Monocytes; Pyrroles | 2000 |
Stimulus history alters behavioral responses of neuronal growth cones.
Topics: Animals; Benzylamines; Carbazoles; Cells, Cultured; Chick Embryo; Electric Stimulation; Enzyme Inhibitors; Ganglia, Spinal; Indoles; Kinetics; Neurites; Neurons; Protein Kinase Inhibitors; Pyrroles; Sulfonamides | 2000 |
Short- and long-term memory are differentially affected by metabolic inhibitors given into hippocampus and entorhinal cortex.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Animals; Avoidance Learning; Carbazoles; Entorhinal Cortex; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Hippocampus; Indoles; Inhibition, Psychological; Male; Memory; Memory, Short-Term; Phenols; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Sodium Chloride; Staurosporine | 2000 |
Cyclic adenosine monophosphate inhibits ursolic acid-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carbazoles; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Indoles; Isoquinolines; Pyrroles; Sulfonamides; Tretinoin; Triterpenes; Ursolic Acid | 2000 |
Natriuretic peptides and diadenosine polyphosphates modulate pH regulation of rat mesangial cells.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Alkaloids; Animals; Atrial Natriuretic Factor; Carbazoles; Cells, Cultured; Dinucleoside Phosphates; Female; Gene Expression Regulation; Glomerular Mesangium; Guanidines; Hydrogen-Ion Concentration; Indoles; Platelet-Derived Growth Factor; Pyrroles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchangers; Sulfones | 1999 |
Theophylline induces neutrophil apoptosis through adenosine A2A receptor antagonism.
Topics: Adenosine; Apoptosis; Carbazoles; Cells, Cultured; Humans; Indoles; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Pyrroles; Receptor, Adenosine A2A; Signal Transduction; Theophylline; Xanthines | 2000 |
Intrahippocampal infusion of an inhibitor of protein kinase A separates short- from long-term memory.
Topics: Amnesia, Retrograde; Animals; Avoidance Learning; Behavior, Animal; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Indoles; Injections; Memory; Memory, Short-Term; Pyrroles; Rats; Rats, Wistar | 1999 |
Involvement of cGMP-dependent protein kinase in the relaxation of ovine pulmonary arteries to cGMP and cAMP.
Topics: Animals; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Indoles; Male; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Artery; Pyrroles; Sheep; Thionucleotides; Vasodilation | 2000 |
A peptide of the alpha 3(IV) chain of type IV collagen modulates stimulated neutrophil function via activation of cAMP-dependent protein kinase and Ser/Thr protein phosphatase.
Topics: Adenosine; Amino Acid Sequence; Autoantigens; Calcium; Carbazoles; Chelating Agents; Collagen; Collagen Type IV; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Antagonists; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; Indoles; Marine Toxins; Molecular Sequence Data; Neutrophils; Okadaic Acid; Oxazoles; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Pyrroles; Pyrrolidinones; Respiratory Burst; Signal Transduction; Thapsigargin; Trifluoperazine | 2000 |
Interplay between nitric oxide and vasoactive intestinal polypeptide in the pig gastric fundus smooth muscle.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Isoquinolines; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxadiazoles; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Sulfonamides; Swine; Thionucleotides; Vasoactive Intestinal Peptide | 2000 |
Regulation of IL-10 secretion after phagocytosis of Mycobacterium tuberculosis by human monocytic cells.
Topics: Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Indoles; Interleukin-10; Interleukin-8; Mycobacterium tuberculosis; Naphthalenes; Phagocytosis; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles | 2000 |
Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Carbazoles; CHO Cells; Cricetinae; Enzyme Inhibitors; Indole Alkaloids; Indoles; N-Methylscopolamine; Pyrroles; Radioligand Assay; Receptors, Muscarinic; Staurosporine | 2000 |
Role of the phosphatidylinositol-specific phospholipase C pathway in delta-opioid receptor-mediated antinociception in the mouse spinal cord.
Topics: Analgesics; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Estrenes; Indoles; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred ICR; Naphthalenes; Oligopeptides; Pain; Pain Measurement; Phosphatidylinositols; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptors, Opioid, delta; Signal Transduction; Spinal Cord; Type C Phospholipases | 2000 |
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Pyrroles; Rats; Receptors, Adrenergic, beta; Urinary Bladder; Virulence Factors, Bordetella | 2000 |
Protein kinase A or C modulates the apoptosis induced by lectin II isolated from Korean mistletoe, Viscum album var. Coloratum, in the human leukemic HL-60 cells.
Topics: Apoptosis; Bucladesine; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Indoles; Lectins; Mistletoe; Plant Lectins; Plant Preparations; Plant Proteins; Plants, Medicinal; Protein Kinase C; Pyrroles; Ribosome Inactivating Proteins, Type 2; Staurosporine; Tetradecanoylphorbol Acetate; Toxins, Biological | 2000 |
Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation.
Topics: Amygdala; Animals; Auditory Cortex; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Indoles; Isoproterenol; Long-Term Potentiation; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Thalamus; Transcription, Genetic | 2000 |
Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors.
Topics: Animals; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Heart Rate; Hydrazines; Indoles; Isoquinolines; Male; Milrinone; Models, Biological; Molsidomine; Nitric Oxide Donors; Nitrogen Oxides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Pyrroles; Quinazolines; Ryanodine; Sarcoplasmic Reticulum; Signal Transduction; Spectrometry, Fluorescence; Sulfonamides; Superoxide Dismutase; Tetrahydroisoquinolines; Thionucleotides; Time Factors; Vasodilator Agents | 2000 |
Desensitization of beta2-adrenoceptor and hypersensitization to phosphodiesterase inhibitors elicited by beta2-agonists in guinea pig eosinophils.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bucladesine; Calcimycin; Carbazoles; Cells, Cultured; Clenbuterol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Eosinophil Peroxidase; Eosinophils; Fenoterol; Guinea Pigs; Indoles; Intracellular Fluid; Ionophores; Male; Peroxidases; Phosphodiesterase Inhibitors; Pyrroles; Receptors, Adrenergic, beta-2; Theophylline; Time Factors | 2000 |
Protein kinase A regulates chondrogenesis of mesenchymal cells at the post-precartilage condensation stage via protein kinase C-alpha signaling.
Topics: Animals; Cadherins; Carbazoles; Cartilage; Cell Differentiation; Chick Embryo; Chondrogenesis; Cyclic AMP-Dependent Protein Kinases; Embryonic Induction; Enzyme Inhibitors; Fibronectins; Flavonoids; Indoles; Isoenzymes; Isoquinolines; Mesoderm; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Pyrroles; Receptors, Fibronectin; Signal Transduction; Sulfonamides | 2000 |
Activation of group II metabotropic glutamate receptors induces long-term depression of synaptic transmission in the rat amygdala.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Amino Acids, Dicarboxylic; Amygdala; Animals; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indoles; Isoproterenol; Male; Neural Inhibition; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time | 2000 |
Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid.
Topics: 8,11,14-Eicosatrienoic Acid; Adenine; ADP Ribose Transferases; Antibodies; Carbazoles; Cells, Cultured; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Indoles; Kidney; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channel beta Subunits; Large-Conductance Calcium-Activated Potassium Channels; Potassium Channels; Potassium Channels, Calcium-Activated; Pyrroles | 2001 |
Iloprost inhibits inositol-1,4,5-trisphosphate-mediated calcium mobilization stimulated by angiotensin II in cultured preglomerular vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Calcium Channels, L-Type; Calcium-Transporting ATPases; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Iloprost; Indoles; Inositol 1,4,5-Trisphosphate; Kidney Glomerulus; Milrinone; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrroles; Rats; Thapsigargin | 2001 |
Involvement of anion exchange in the hypoxia/reoxygenation-induced changes in pH(i) and.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Bicarbonates; Calcium; Carbazoles; Cells, Cultured; Chlorides; Electric Stimulation; Enzyme Inhibitors; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Ion Transport; Male; Muscle Contraction; Naphthalenes; Oxygen; Papillary Muscles; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley | 2001 |
G protein and cAMP-dependent protein kinase mediate amyloid beta-peptide inhibition of neuronal glucose uptake.
Topics: Adenylyl Cyclases; Amyloid beta-Peptides; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; GTP-Binding Proteins; Hippocampus; Indoles; Neurons; Peptide Fragments; Pyrroles; Rats; Rats, Sprague-Dawley | 2001 |
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Carcinogens; Cephaloridine; Cephalosporins; Cyclic AMP; Enzyme Inhibitors; Free Radicals; Gluconeogenesis; In Vitro Techniques; Indoles; Kidney Cortex; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; p-Aminohippuric Acid; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.
Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates | 2001 |
Increase in number of functional release sites by cyclic AMP-dependent protein kinase in cultured neurons isolated from hippocampal dentate gyrus.
Topics: Animals; Animals, Newborn; Calcium; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Dentate Gyrus; Enzyme Inhibitors; Exocytosis; Extracellular Space; Indoles; Long-Term Potentiation; Neurotransmitter Agents; Potassium Chloride; Presynaptic Terminals; Protein Kinases; Pyrroles; Rats; Signal Transduction; Strontium; Synaptic Transmission; Thionucleotides | 2001 |
Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance.
Topics: Antigens, Nuclear; Antineoplastic Agents; Carbazoles; Cyclic AMP-Dependent Protein Kinases; DNA Helicases; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; Ku Autoantigen; NF-kappa B; Nuclear Proteins; Pyrroles; Sulfonamides; Tumor Cells, Cultured | 2001 |
The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells.
Topics: Animals; Arachidonic Acid; Axons; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genes, fos; Genes, Reporter; Hippocampus; Indoles; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Neoplasm Proteins; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Neurites; PC12 Cells; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Pyrroles; Rats; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thionucleotides; Transcription, Genetic; Transfection | 2001 |
Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis.
Topics: Adenylyl Cyclases; Breast Neoplasms; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Humans; Indoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-raf; Pyrroles; Receptors, Cell Surface; Receptors, Estrogen; Receptors, G-Protein-Coupled; Tamoxifen; Tumor Cells, Cultured | 2002 |
Glucagon acutely inhibits but chronically activates Na(+)/H(+) antiporter 3 activity in OKP cells.
Topics: Animals; Biological Transport; Carbazoles; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Glucagon; Hydrogen-Ion Concentration; Indoles; Kidney; Opossums; Pyrroles; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2002 |
Cyclic AMP-dependent protein kinase A plays a role in the directed migration of human keratinocytes in a DC electric field.
Topics: Azepines; Carbazoles; Cell Movement; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Inhibitors; Epithelium; Humans; Indoles; Keratinocytes; Myosin-Light-Chain Kinase; Naphthalenes; Protein Kinase C; Pyrroles; Signal Transduction; Wound Healing | 2001 |
Rapid component I(Kr) of the guinea-pig cardiac delayed rectifier K(+) current is inhibited by beta(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Indoles; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Xamoterol | 2002 |
Differential regulation of MMP-1/9 and TIMP-1 secretion in human monocytic cells in response to Mycobacterium tuberculosis.
Topics: Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Indoles; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Monocytes; Mycobacterium tuberculosis; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Zymosan | 2002 |
Selective excitation of GABAergic neurons in the substantia nigra of the rat by orexin/hypocretin in vitro.
Topics: Animals; Carbazoles; Carrier Proteins; Dopamine; Electrophysiology; gamma-Aminobutyric Acid; Indoles; Intracellular Signaling Peptides and Proteins; Male; Neurons; Neuropeptides; Orexins; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Substantia Nigra; Thapsigargin | 2002 |
Growth hormone can regulate functions of porcine ovarian granulosa cells through the cAMP/protein kinase A system.
Topics: Animals; Apoptosis; Carbazoles; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Granulosa Cells; Growth Hormone; Immunohistochemistry; In Situ Nick-End Labeling; Indoles; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Oxytocin; Prostaglandins F; Pyrroles; Swine | 2002 |
The influence of the protein kinase A system in differentiation of HL-60-Eo cells to eosinophils induced by histamine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Eosinophils; Histamine; HL-60 Cells; Humans; Indoles; Oligonucleotides, Antisense; Protein Subunits; Pyrroles; Thymidine | 2001 |
Cyclic AMP inhibits stretch-induced overexpression of fibronectin in glomerular mesangial cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Bucladesine; Carbazoles; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Epoprostenol; Fibronectins; Gene Expression Regulation; Glomerular Mesangium; Indoles; Male; Mitogen-Activated Protein Kinases; Nuclear Proteins; Oligonucleotides; Protein Binding; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Transcription Factor AP-1 | 2002 |
Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Isoquinolines; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Rats; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2002 |
Protein kinase-dependent and Ca(2+)-independent cAMP inhibition of ANP release in beating rabbit atria.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Indoles; Myocardial Contraction; Myocardium; Nifedipine; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rabbits; Staurosporine | 2002 |
Inhibition of spontaneous acetylcholine secretion by 2-chloroadenosine as revealed by a protein kinase inhibitor at the mouse neuromuscular junction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Acetylcholine; Animals; Carbazoles; Carrier Proteins; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Neuromuscular Junction; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrroles; Staurosporine; Thionucleotides | 2002 |
Okadaic acid inhibits relaxant neural transmission in rat gastric fundus in vitro.
Topics: Animals; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Gastrointestinal Agents; Hydrazines; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitrogen Oxides; Okadaic Acid; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Purinones; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Vasoactive Intestinal Peptide | 2002 |
Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone.
Topics: Animals; Bone and Bones; Carbazoles; Carrier Proteins; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Endothelium, Vascular; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoclasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Pyridines; Pyrroles; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; RNA, Messenger; Transforming Growth Factor beta | 2002 |
Sunghyangjungisan protects PC12 cells against neurotoxicity elicited by withdrawal of trophic support via CRE activation.
Topics: Animals; Carbazoles; Caspase 3; Caspase Inhibitors; Culture Media, Serum-Free; Cyclic AMP Response Element-Binding Protein; Cytoprotection; DNA Fragmentation; Dose-Response Relationship, Drug; Indoles; Medicine, East Asian Traditional; Neuroprotective Agents; PC12 Cells; Phosphorylation; Plant Extracts; Plants, Medicinal; Pyrroles; Rats; Serine Proteinase Inhibitors; Time Factors | 2002 |
Protein kinase A regulates beta2 integrin avidity in neutrophils.
Topics: Carbazoles; CD18 Antigens; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flow Cytometry; Humans; Indoles; Isoquinolines; Kinetics; Ligands; Neutrophils; Pyrroles; Signal Transduction; Sulfonamides | 2002 |
Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analysis of Variance; Animals; Bucladesine; Calcium; Carbazoles; Chelating Agents; Cholagogues and Choleretics; Cholestasis; Cholic Acids; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Indoles; Liver; Male; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Taurochenodeoxycholic Acid; Taurolithocholic Acid | 2002 |
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells.
Topics: Actin Cytoskeleton; Apoptosis; Carbazoles; Cell Cycle; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Epithelial Cells; Flow Cytometry; Humans; Indoles; Inhibitory Concentration 50; KB Cells; Microscopy, Fluorescence; Pyrroles; Theophylline; Time Factors; Transglutaminases; Tumor Cells, Cultured | 2002 |
Prostacyclin analogs inhibit fibroblast migration.
Topics: Becaplermin; Carbazoles; Cell Line; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epoprostenol; Fibroblasts; Fibronectins; Humans; Indoles; Lung; Osmolar Concentration; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyrroles | 2002 |
The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Indoles; Kidney Cortex; Kidney Medulla; Male; Okadaic Acid; Phosphodiesterase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2002 |
Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Carbazoles; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Membrane Potentials; Muscle, Smooth, Vascular; Naphthalenes; Norepinephrine; Phenanthridines; Portal Vein; Prazosin; Propranolol; Pyrroles; Pyrrolidinones; Rabbits; Tetradecanoylphorbol Acetate | 2002 |
PGD(2) modulates fibroblast-mediated native collagen gel contraction.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Collagen; Cyclic GMP; Enzyme Inhibitors; Estrenes; Fatty Acids, Unsaturated; Fibroblasts; Gels; Humans; Hydrazines; Indoles; Lung; Mesylates; Naphthalenes; Prostaglandin Antagonists; Prostaglandin D2; Protein Kinase C; Pyrroles; Pyrrolidinones; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Thionucleotides; Type C Phospholipases; Wound Healing; Xanthenes; Xanthones | 2002 |
The in vitro effects of Pb acetate on NO production by C6 glial cells.
Topics: Animals; Carbazoles; Cytokines; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Glioma; Indoles; Neuroglia; Nitric Oxide; Organometallic Compounds; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Staurosporine; Tumor Cells, Cultured | 2002 |
Protein kinase G activates inwardly rectifying K(+) channel in cultured human proximal tubule cells.
Topics: Adult; Algorithms; Alkaloids; Atrial Natriuretic Factor; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Female; Guanylate Cyclase; Humans; Indoles; Kidney Tubules, Proximal; Microscopy, Electron, Scanning; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Stimulation, Chemical | 2002 |
Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.
Topics: Androstadienes; Animals; Bile Acids and Salts; Bile Canaliculi; Carbazoles; Cell Line; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; ras Proteins; Rats; Time Factors; Wortmannin | 2002 |
Protein kinase C (PKC) dependent induction of tissue factor (TF) by mesangial cells in response to inflammatory mediators and release during apoptosis.
Topics: Apoptosis; Calcium; Carbazoles; Cell Line; Cells, Cultured; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glomerular Mesangium; Humans; Hydrogen Peroxide; Indoles; Inflammation Mediators; Interleukin-1; Lipopolysaccharides; Naphthalenes; Protein Kinase C; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboplastin; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets.
Topics: Animals; ATP-Binding Cassette Transporters; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Mice; Mice, Knockout; Peptide Fragments; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrroles; Receptors, Drug; Reference Values; Sulfonamides; Sulfonylurea Receptors | 2002 |
Peroxisome proliferator-activated receptor gamma thiazolidinedione agonists increase glucose metabolism in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Carbazoles; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glycolysis; Hypoglycemic Agents; In Vitro Techniques; Indoles; Kinetics; Lactates; Monosaccharide Transport Proteins; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism.
Topics: Acetylcysteine; Animals; Antibodies; Blotting, Western; Caenorhabditis elegans Proteins; Carbazoles; Carrier Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Drosophila; Drosophila Proteins; Drug Interactions; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Helminth Proteins; Horseradish Peroxidase; Immunohistochemistry; Indoles; Insect Proteins; Maleimides; Microscopy, Confocal; Multienzyme Complexes; Mutation; Neomycin; Neuromuscular Junction; Oligopeptides; Phorbol Esters; Phospholipid Ethers; Presynaptic Terminals; Proteasome Endopeptidase Complex; Pyrroles; Pyrrolidinones; Synapses; Tumor Suppressor Proteins; Type C Phospholipases | 2003 |
Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbazoles; Cell Membrane; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Naphthalenes; Ovariectomy; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Staurosporine | 2002 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin | 2003 |
Reexamination of the role of hyperpolarization-activated cation channels in short- and long-term plasticity at hippocampal mossy fiber synapses.
Topics: Animals; Carbazoles; Cesium; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Cyclopropanes; Dizocilpine Maleate; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glycine; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Indoles; Ion Channels; Long-Term Potentiation; Membrane Potentials; Mice; Mice, Inbred ICR; Mossy Fibers, Hippocampal; Nerve Tissue Proteins; Neuronal Plasticity; Patch-Clamp Techniques; Potassium Channels; Pyrimidines; Pyrroles; Synapses | 2003 |
Astrocyte stellation induced by Rho kinase inhibitors in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Astrocytes; Carbazoles; Cell Size; Cells, Cultured; Cerebral Cortex; Colchicine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gout Suppressants; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Phalloidine; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; rho-Associated Kinases | 2003 |
Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes.
Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Aminobenzoates; Animals; Atrial Natriuretic Factor; Benzophenanthridines; Benzothiazoles; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Heart; Heart Atria; Imines; Indoles; Isoquinolines; Ketanserin; Male; Myocytes, Cardiac; Neomycin; para-Aminobenzoates; Perfusion; Phenanthridines; Piperazines; Piperidines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Staurosporine; Sulfonamides; Thiazoles; Type C Phospholipases | 2003 |
Inositol derivatives modulate spontaneous transmitter release at the frog neuromuscular junction.
Topics: Action Potentials; Animals; Antibodies; Carbazoles; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Enzyme Inhibitors; In Vitro Techniques; Indoles; Inositol; Inositol Polyphosphate 5-Phosphatases; Isoquinolines; Liposomes; Neuromuscular Junction; Neurotransmitter Agents; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Pyrroles; Rana pipiens; Sulfonamides | 2003 |
The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA.
Topics: Analgesics; Animals; Brain; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Enzyme Inhibitors; Indoles; Injections, Intraventricular; Isoquinolines; Male; Maleimides; Mice; Morphine; Morphine Dependence; Pain; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrroles | 2003 |
New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium; Calcium Channels; Capsaicin; Carbazoles; Conotoxins; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Indoles; Iris; Maleimides; Muscle Contraction; Nicardipine; omega-Agatoxin IVA; Peptide Fragments; Piperidines; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Receptors, Calcitonin Gene-Related Peptide; Receptors, Drug; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Swine; Tachykinins | 2003 |
cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Apoptosis; Carbazoles; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; Indoles; Islets of Langerhans; Isoquinolines; Mice; Palmitates; Pyrroles; Signal Transduction; Sulfonamides | 2004 |
cAMP inhibits natriuretic peptide receptor-B activity and increases C-type natriuretic peptide in FRTL-5 rat thyroid cells.
Topics: Animals; Bucladesine; Calcium; Carbazoles; Cell Line; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Guanylate Cyclase; Immunohistochemistry; Indoles; Isoquinolines; Natriuretic Peptide, C-Type; Pyrroles; Rats; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Thyroid Gland; Thyrotropin; Time Factors | 2004 |
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.
Topics: Adenine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Procaterol; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Suramin; Xamoterol | 2004 |
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.
Topics: Alanine; Animals; Blotting, Western; Calcineurin; Calcium; Carbazoles; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Exocytosis; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Kidney; Membrane Potentials; Membrane Proteins; Models, Biological; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Photolysis; Pyrethrins; Pyrroles; Secretory Vesicles; Synaptosomal-Associated Protein 25; Threonine; Time Factors; Transfection | 2004 |
Arginase induction promotes Trypanosoma cruzi intracellular replication in Cruzipain-treated J774 cells through the activation of multiple signaling pathways.
Topics: Animals; Arginase; Arginine; Carbazoles; Cell Division; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Enzyme Induction; Genistein; Growth Inhibitors; Imidazoles; Indoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Protozoan Proteins; Pyridines; Pyrroles; Signal Transduction; Trypanosoma cruzi | 2004 |
Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Animals; Benzylamines; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Glycerol; Hydroxycholesterols; Indoles; Lignans; Lipolysis; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naphthalenes; Oleic Acid; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles | 2004 |
Corticotropin-releasing factor and urocortin differentially modulate rat Purkinje cell dendritic outgrowth and differentiation in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calbindins; Carbazoles; Cell Count; Cell Differentiation; Corticotropin-Releasing Hormone; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavonoids; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Indoles; Linear Models; Neuroprotective Agents; Purkinje Cells; Pyrimidines; Pyrroles; Rats; S100 Calcium Binding Protein G; Time Factors; Urocortins | 2004 |
Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy.
Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Carbazoles; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Histamine H1 Antagonists; Humans; Indoles; Isoproterenol; Phosphorylation; Pyrilamine; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Histamine H1 | 2004 |
Regulation of an inwardly rectifying K+ channel by nitric oxide in cultured human proximal tubule cells.
Topics: Adult; Carbazoles; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Indoles; Kidney Tubules, Proximal; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles | 2004 |
Cyclic adenosine monophosphate (cAMP) increases natriuretic peptide receptor C (NPR-C) expression in human aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Atrial Natriuretic Factor; Bucladesine; Carbazoles; Cell Culture Techniques; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Guanylate Cyclase; Humans; Indoles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Binding; Pyrroles; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Signal Transduction | 2004 |
Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase.
Topics: Bucladesine; Carbazoles; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Humans; Indoles; Phospholipase D; Phosphorylation; Pyrroles; rhoA GTP-Binding Protein | 2004 |
PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice.
Topics: Analgesics, Opioid; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Tolerance; Hypothermia, Induced; Indoles; Injections, Intraventricular; Injections, Spinal; Male; Maleimides; Mice; Morphine; Pain Measurement; Protein Kinase C; Pyrroles; Tail | 2004 |
Mechanism of CGRP-induced vasodilation in the rat isolated perfused kidney.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Indoles; Indomethacin; Kidney; Nitroarginine; Octoxynol; Peptide Fragments; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Vasodilation | 2004 |
The relaxant effect of urocortin in rat pulmonary arteries.
Topics: Animals; Barium Compounds; Carbazoles; Chlorides; Corticotropin-Releasing Hormone; Endothelium; Indoles; Muscle Relaxation; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Pulmonary Artery; Pyrroles; Rats; Urocortins | 2004 |
Repetitive exposures to nicotine induce a hyper-responsiveness via the cAMP/PKA/CREB signal pathway in Drosophila.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Brain Chemistry; Carbazoles; Conditioning, Classical; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Indoles; Male; Motor Activity; Nicotine; Nicotinic Agonists; Protein Synthesis Inhibitors; Pyrroles; Reflex, Startle; Rolipram; Signal Transduction; Time Factors | 2004 |
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Topics: Adenosine; Animals; Carbazoles; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Indoles; Male; Membrane Potentials; N-Methylaspartate; Phenethylamines; Phenylacetates; Pregnancy; Purinergic P1 Receptor Agonists; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Triazines; Triazoles | 2004 |
Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors.
Topics: Action Potentials; Adaptation, Physiological; Animals; Bicuculline; Biomarkers; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dendrites; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indoles; N-Methylaspartate; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Transport; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Strychnine; Synapses; Synapsins; Tetrodotoxin | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Carbazoles; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclooxygenase 2; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Indoles; Isoquinolines; Jurkat Cells; Luciferases; Membrane Proteins; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrroles; RNA, Messenger; Rolipram; Sulfonamides; T-Lymphocytes; Transcription Factors; Transcriptional Activation; Transfection | 2004 |
Modulation of ion uptake across posterior gills of the crab Chasmagnathus granulatus by dopamine and cAMP.
Topics: Animals; Biological Transport; Brachyura; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Epithelium; Gills; Indoles; Ions; Male; Membrane Potentials; Pyrroles; Sodium-Potassium-Exchanging ATPase; Time Factors | 2004 |
Both cAMP and cGMP are required for maximal ciliary beat stimulation in a cell-free model of bovine ciliary axonemes.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbazoles; Cattle; Cell-Free System; Cilia; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Indoles; Nucleotides, Cyclic; Pyrroles | 2005 |
Protein kinase A mediates microglial activation induced by plasminogen and gangliosides.
Topics: Animals; Carbazoles; Cell Line; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gangliosides; Gene Expression Regulation; Indoles; Interleukin-1; Isoquinolines; Mice; Microglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plasminogen; Pyrroles; Rats; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha | 2004 |
Cytochrome P4502C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Carbazoles; Celecoxib; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; DNA, Antisense; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Humans; Indoles; Membrane Proteins; Molecular Sequence Data; Morphogenesis; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrroles; Recombinant Fusion Proteins; RNA, Messenger; Stress, Mechanical; Sulfaphenazole; Sulfonamides; Transcription Factors; Transduction, Genetic; Umbilical Veins | 2005 |
Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells.
Topics: Animals; Axons; Carbazoles; Cell Survival; Chromones; Ciliary Neurotrophic Factor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Flavonoids; Indoles; MAP Kinase Signaling System; Morpholines; Nerve Regeneration; Optic Nerve Injuries; Peroneal Nerve; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Inbred F344; Receptor, Ciliary Neurotrophic Factor; Retinal Ganglion Cells; Signal Transduction; STAT3 Transcription Factor; Thionucleotides; Trans-Activators; Tyrphostins; Up-Regulation | 2004 |
Inhibition of the endothelial cell activation by antithrombin in vitro.
Topics: Anti-Inflammatory Agents; Antithrombins; Blotting, Western; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Immunohistochemistry; Immunoprecipitation; In Vitro Techniques; Indoles; Interleukin-1; Lipopolysaccharides; NF-kappa B; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Pyrroles; RNA, Messenger; Time Factors; Trans-Activators; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
Thrombopoietin regulates proliferation, apoptosis, secretory activity and intracellular messengers in porcine ovarian follicular cells: involvement of protein kinase A.
Topics: Androstenedione; Animals; Apoptosis; Carbazoles; CDC2 Protein Kinase; Cell Proliferation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Estradiol; Female; Immunoblotting; Immunohistochemistry; Indoles; Inhibins; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Ovarian Follicle; Oxytocin; Phosphotyrosine; Progesterone; Pyrroles; Swine; Thrombopoietin; Transforming Growth Factor beta | 2004 |
Adenylyl cyclase-cAMP system inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Topics: Adenylyl Cyclases; Adjuvants, Immunologic; Animals; Animals, Newborn; Bucladesine; Carbazoles; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Indoles; Mice; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Osteoblasts; Osteocalcin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Pyrroles; Triiodothyronine | 2005 |
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic beta-Agonists; Amino Acids; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Dendritic Spines; Disks Large Homolog 4 Protein; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Immunoprecipitation; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Membrane Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Kinase Inhibitors; Pseudopodia; Pyrroles; Rats; Receptor, trkB; Thionucleotides; Transfection | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production.
Topics: Aminoquinolines; Apoptosis; Carbazoles; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagenases; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelin-1; Enzyme Induction; Female; Guanylate Cyclase; Humans; Imidazoles; Indoles; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis, Knee; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Pyrroles; Signal Transduction | 2005 |
Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA.
Topics: Adenosine Diphosphate; Animals; Carbazoles; Cell Membrane; Cell Proliferation; Cell Separation; Cells, Cultured; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fibronectins; Fluorescent Antibody Technique; Immunohistochemistry; Indoles; Integrin beta1; Membrane Proteins; Microglia; Pyrroles; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12 | 2005 |
Effects of rolipram on induction of action potential bursts in central snail neurons.
Topics: Action Potentials; Animals; Carbazoles; Cell Membrane; Central Nervous System; Colforsin; Cyclic AMP; Estrenes; Ganglia, Invertebrate; Indoles; Magnesium; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phospholipases; Phosphoric Diester Hydrolases; Pyrroles; Pyrrolidinones; Rolipram; Signal Transduction; Snails; Synaptic Transmission | 2005 |
The role of protein kinase A and cyclin-dependent (CDC2) kinase in the control of basal and IGF-II-induced proliferation and secretory activity of chicken ovarian cells.
Topics: Animals; Carbazoles; Cell Growth Processes; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 2; Estradiol; Female; Granulosa Cells; Indoles; Insulin-Like Growth Factor II; Kinetin; Ovarian Follicle; Progesterone; Protein Kinase Inhibitors; Pyrroles; Testosterone; Theca Cells; Vasotocin | 2006 |
Effects of a new isoquinolinone derivative on induction of action potential bursts in central snail neuron.
Topics: Action Potentials; Animals; Calcium; Carbazoles; Chlorpheniramine; Cimetidine; Estrenes; Indoles; Isoquinolines; Lithium; Magnesium; Neomycin; Neurons; Phospholipases; Potassium; Pyridines; Pyrroles; Pyrrolidinones; Snails; Sulfonamides | 2005 |
Excitatory actions of dopamine via D1-like receptors in the rat lateral geniculate nucleus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Bromocriptine; Carbazoles; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Geniculate Bodies; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Prazosin; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tetrodotoxin; Thionucleotides | 2005 |
Cyclic nucleotide regulation of store-operated Ca2+ influx in airway smooth muscle.
Topics: Animals; Calcium; Calcium Channels; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Indoles; Muscle, Smooth; Pyrroles; Swine; Trachea | 2006 |
Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons.
Topics: Animals; Antioxidants; Carbazoles; Catalytic Domain; Chromatin Immunoprecipitation; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Deferoxamine; DNA, Mitochondrial; Humans; Indoles; Mice; Mitochondria; Neurons; Oxidative Stress; Phosphorylation; Protein Subunits; Pyrroles; Rats; Signal Transduction | 2005 |
Neonatal isolation accelerates the developmental switch in the signalling cascades for long-term potentiation induction.
Topics: Age Factors; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Indoles; Long-Term Potentiation; Maternal Deprivation; Neurons; Peptide Fragments; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Signal Transduction; Synaptic Transmission | 2005 |
Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes.
Topics: B-Lymphocytes; Blotting, Western; Carbazoles; Cell Proliferation; Cell Transformation, Viral; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D2; Cyclins; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Humans; Indoles; Interleukin-2; Isoquinolines; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrroles; Sulfonamides; T-Lymphocytes; Transcription, Genetic | 2006 |
The existence of a second allosteric site on the M1 muscarinic acetylcholine receptor and its implications for drug design.
Topics: Allosteric Site; Carbazoles; Drug Design; Indoles; Models, Molecular; Protein Structure, Tertiary; Pyrroles; Receptor, Muscarinic M1 | 2006 |
Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers.
Topics: Amiloride; Biological Transport; Biotinylation; Brefeldin A; Carbazoles; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Epithelial Sodium Channels; Genistein; Green Fluorescent Proteins; Humans; Immunoblotting; Immunoprecipitation; Indoles; Ions; Lung; Microscopy, Confocal; Protein Structure, Tertiary; Protein Transport; Protein-Tyrosine Kinases; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium Channels; Transfection | 2006 |
Phagocytosis by Lymnaea stagnalis haemocytes: a potential role for phosphatidylinositol 3-kinase but not protein kinase A.
Topics: Animals; Carbazoles; Chromones; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hemocytes; Indoles; Lymnaea; Morpholines; Phagocytosis; Phosphatidylinositol 3-Kinases; Pyrroles | 2006 |
Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells.
Topics: Animals; Carbazoles; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Indoles; Isoquinolines; Male; Muscle, Smooth, Vascular; Potassium Channels, Voltage-Gated; Pyrroles; Rabbits; Sulfonamides; Thionucleotides | 2006 |
Protein kinase A regulates the sensitivity of spinal commissural axon turning to netrin-1 but does not switch between chemoattraction and chemorepulsion.
Topics: Animals; Axons; Blotting, Western; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Indoles; Nerve Growth Factors; Netrin-1; Neurons; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors; Tumor Suppressor Proteins | 2006 |
In vitro and in vivo reversal of MDR1-mediated multidrug resistance by KT-5720: implications on hematological malignancies.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Carbazoles; Cell Line, Tumor; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Mice, Transgenic; Multiple Myeloma; Pyrroles | 2006 |
Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane.
Topics: Adrenergic beta-Agonists; Animals; Carbazoles; Cell Membrane; Cells, Cultured; Diagnostic Imaging; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Green Fluorescent Proteins; Hippocampus; Indoles; Isoproterenol; Microscopy, Video; Microtubule-Associated Proteins; Neurons; Pyrroles; Rats; Receptors, Adrenergic, beta-2; Time Factors; Transfection | 2006 |
Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic tagging.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Female; Hippocampus; In Vitro Techniques; Indoles; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Okadaic Acid; Pyrroles; Signal Transduction; Synapses | 2006 |
cAMP-PKA signaling pathway regulates bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
Topics: Animals; Antibodies; Bone Resorption; Carbazoles; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Lysosomes; Mannose; Mice; Monensin; Naphthalenes; Osteoclasts; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Receptor, IGF Type 2; Signal Transduction; Sulfonamides | 2006 |
Will MDR-1/P-gp modulators provide clinical benefit in hematologic malignancies?
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Carbazoles; Cell Line, Tumor; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Mice, Transgenic; Multiple Myeloma; Pyrroles | 2006 |
Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats.
Topics: Animals; Antithrombins; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Endotoxins; Ganglia, Spinal; Gene Expression Regulation; Hypotension; Indoles; Indomethacin; Lung; Male; Neurons, Afferent; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peptide Fragments; Polyunsaturated Alkamides; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; RNA, Messenger; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2006 |
A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes.
Topics: Amino Acid Sequence; Animals; Apoptosis; B-Lymphocytes; bcl-Associated Death Protein; Carbazoles; Cattle; Cell Proliferation; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Recombinant Fusion Proteins; Serine; Sulfonamides; Theileria annulata; Theileriasis; Up-Regulation | 2006 |
Regulation of the cardiac L-type calcium channel in L6 cells by arginine-vasopressin.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Arginine Vasopressin; Barium; Calcium Channels, L-Type; Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Estrenes; GTP-Binding Proteins; Indoles; Myocardium; Protein Kinase C; Pyrroles; Pyrrolidinones; Rats | 2006 |
Ghrelin inhibits angiotensin II-induced migration of human aortic endothelial cells.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Angiotensin II; Aorta; Carbazoles; Cell Movement; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Ghrelin; Humans; Indoles; Oligopeptides; Peptide Hormones; Proto-Oncogene Proteins c-akt; Pyrroles | 2007 |
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles | 2007 |
Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.
Topics: Animals; Anthracenes; Carbazoles; Cell Movement; Colon; Enteric Nervous System; Glial Cell Line-Derived Neurotrophic Factor; Indoles; Mice; Mice, Mutant Strains; Mutation; Neural Crest; Proto-Oncogene Proteins c-ret; Pyrroles; Signal Transduction | 2006 |
Repeated cocaine administration promotes long-term potentiation induction in rat medial prefrontal cortex.
Topics: Animals; Benzazepines; Carbazoles; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electrophysiology; Enzyme Inhibitors; gamma-Aminobutyric Acid; Indoles; Long-Term Potentiation; Male; Motor Activity; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Pyrroles; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Dopamine D1; Receptors, GABA-A; Stimulation, Chemical | 2007 |
Direct modulation of Ca(2+)-activated K(+) current by H-89 in rabbit coronary arterial smooth muscle cells.
Topics: Animals; Carbazoles; Coronary Circulation; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indoles; Isoquinolines; Membrane Potentials; Muscle, Smooth, Vascular; Okadaic Acid; Patch-Clamp Techniques; Phosphoprotein Phosphatases; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Pyrroles; Rabbits; Sulfonamides; Thionucleotides; Time Factors; Vascular Resistance | 2007 |
PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Temperature; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Drug Implants; Drug Tolerance; Enzyme Inhibitors; Hot Temperature; Hypothermia; Indoles; Injections, Intraventricular; Isoquinolines; Male; Maleimides; Mice; Morphine; Pain; Protein Kinase C; Pyrroles; Reaction Time | 2006 |
Anti-apoptotic effects of 3,5,3'-tri-iodothyronine in mouse hepatocytes.
Topics: Animals; Annexin A5; Apoptosis; Biomarkers; Carbazoles; Caspase 8; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Flow Cytometry; Hepatocytes; In Situ Nick-End Labeling; Indoles; Male; Mice; Phosphorylation; Pyrroles; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Triiodothyronine; Tumor Necrosis Factor-alpha | 2006 |
Nerve growth factor enhances voltage-gated Na+ channel activity and Transwell migration in Mat-LyLu rat prostate cancer cell line.
Topics: Animals; Carbazoles; Cell Line, Tumor; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Indole Alkaloids; Indoles; Male; NAV1.7 Voltage-Gated Sodium Channel; Nerve Growth Factor; Patch-Clamp Techniques; Prostatic Neoplasms; Pyrroles; Rats; Receptors, Nerve Growth Factor; RNA, Messenger; Sodium Channels; Time Factors; Up-Regulation | 2007 |
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron.
Topics: Action Potentials; Alkaloids; Animals; Benzophenanthridines; Calcium; Carbazoles; Electrophysiology; Enzyme Inhibitors; Estrenes; Ganglia, Invertebrate; Hallucinogens; In Vitro Techniques; Indoles; Isoquinolines; Magnesium; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrroles; Pyrrolidinones; Snails; Sulfonamides; Tetradecanoylphorbol Acetate | 2007 |
Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Precursors; Guanine Nucleotide Exchange Factors; Indoles; Male; Pancreas, Exocrine; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley | 2007 |
Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Apoptosis; Carbazoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Immunologic Factors; Indoles; Interferon-alpha; Pyrroles; Signal Transduction | 2007 |
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea | 2007 |
Prostacyclin analogs inhibit fibroblast contraction of collagen gels through the cAMP-PKA pathway.
Topics: Carbazoles; Cell Survival; Cells, Cultured; Collagen; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epoprostenol; Extracellular Matrix; Fibroblasts; Fibronectins; Gels; Humans; Indoles; Lung; Pyrroles | 2007 |
Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cyclic GMP; Enzyme Inhibitors; HeLa Cells; Histamine; Histamine H1 Antagonists; Humans; Indoles; Luciferases; Protein Kinase C; Pyrilamine; Pyrroles; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Transfection; Tritium; Up-Regulation | 2007 |
The neuropeptide corticotropin-releasing factor regulates excitatory transmission and plasticity at the climbing fibre-Purkinje cell synapse.
Topics: Animals; Animals, Newborn; Carbazoles; Cerebellum; Corticotropin-Releasing Hormone; Drug Interactions; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indoles; Neuronal Plasticity; Peptide Fragments; Purkinje Cells; Pyrroles; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2007 |
Signaling mechanisms leading to regulation of proliferation and differentiation of the mesenchymal chondrogenic cell line RCJ3.1C5.18 in response to IGF-I.
Topics: Animals; Antigens, Differentiation; Butadienes; Carbazoles; Cell Differentiation; Cell Line; Cell Proliferation; Chondrocytes; Chromones; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Indoles; Insulin-Like Growth Factor I; Isoquinolines; Maleimides; MAP Kinase Signaling System; Mesoderm; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Sulfonamides | 2007 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fetal Development; Gestational Age; Heart; Heart Ventricles; Indoles; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Pyrroles; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2007 |
Acute hypoxia induces vasodilation and increases coronary blood flow by activating inward rectifier K(+) channels.
Topics: Acute Disease; Adenine; Animals; Blood Pressure; Carbazoles; Coronary Circulation; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Glyburide; Hypoxia; In Vitro Techniques; Indoles; Male; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyrroles; Rabbits; Signal Transduction; Thionucleotides; Vasodilation | 2007 |
Phosphatidylinositol 3-kinase is involved in prostaglandin E2-mediated murine duodenal bicarbonate secretion.
Topics: Androstadienes; Animals; Bicarbonates; Calcium Signaling; Carbazoles; Chromones; Cyclic AMP; Dinoprostone; Duodenum; Flavonoids; Genistein; Imines; Indoles; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Sulfonamides; Verapamil; Wortmannin | 2007 |
Atrial natriuretic peptide reduces ischemia/reperfusion-induced spinal cord injury in rats by enhancing sensory neuron activation.
Topics: 6-Ketoprostaglandin F1 alpha; Anilides; Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Capsaicin; Carbazoles; Cells, Cultured; Cinnamates; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Indomethacin; Male; Neurons, Afferent; Peroxidase; Psychomotor Performance; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord; Spinal Cord Diseases; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2007 |
A protein kinase A-dependent mechanism by which rotavirus affects the distribution and mRNA level of the functional tight junction-associated protein, occludin, in human differentiated intestinal Caco-2 cells.
Topics: Animals; Caco-2 Cells; Carbazoles; Cell Fractionation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Indoles; Intestines; Isoquinolines; Membrane Proteins; Microscopy, Confocal; Occludin; Octoxynol; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Rotavirus; Sulfonamides; Thionucleotides; Tight Junctions; Transcription, Genetic; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein | 2007 |
Involvement of protein kinase A in nitric oxide stimulating effect on a BK(Ca) channel of human dermal fibroblasts.
Topics: Adenylyl Cyclases; Adolescent; Carbazoles; Cells, Cultured; Child; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dermis; Electrophysiology; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Patch-Clamp Techniques; Pyrroles; Signal Transduction | 2007 |
Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C.
Topics: Animals; Biological Transport; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Inositol; Kinetics; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sphingosine; Staurosporine; Trypanosoma cruzi | 2007 |
Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Cannabinoid Receptor Modulators; Carbazoles; Chlorides; Colforsin; Cyclic AMP; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; In Vitro Techniques; Indoles; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrroles; Signal Transduction | 2008 |
Rosmarinic acid induces melanogenesis through protein kinase A activation signaling.
Topics: Animals; Carbazoles; Cell Line, Tumor; Cinnamates; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Depsides; Enzyme Activation; Indoles; Isoquinolines; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Rosmarinic Acid; Signal Transduction; Sulfonamides | 2007 |
Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network.
Topics: Actins; Animals; Apolipoprotein A-I; Apolipoproteins E; Calcium Signaling; Carbazoles; Carrier Proteins; Cell Line; Cell Transplantation; Chelating Agents; Colchicine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Female; Humans; Indoles; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubules; Peptide Fragments; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Sulfonamides; Time Factors; Tubulin Modulators; Vinblastine | 2007 |
Role for cAMP-protein kinase A signalling in augmented neutrophil adhesion and chemotaxis in sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Carbazoles; Cell Adhesion; Chemotaxis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fibronectins; Humans; Hydroxyurea; Indoles; Interleukin-8; Male; Middle Aged; Neutrophils; Pyrroles; Signal Transduction | 2007 |
Hydrogen peroxide stimulates chloride secretion in primary inner medullary collecting duct cells via mPGES-1-derived PGE2.
Topics: Amiloride; Animals; Biological Transport; Carbazoles; Cells, Cultured; Chlorides; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Intramolecular Oxidoreductases; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Mice; Mice, Knockout; Microsomes; Oxidants; Prostaglandin-E Synthases; Protein Kinase Inhibitors; Pyrroles; Sodium Chloride; Sulfonamides | 2007 |
Inhibition of caspase-dependent spontaneous apoptosis via a cAMP-protein kinase A dependent pathway in neutrophils from sickle cell disease patients.
Topics: Adult; Anemia, Sickle Cell; Annexin A5; Antisickling Agents; Apoptosis; Biomarkers; Carbazoles; Case-Control Studies; Caspase 3; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Flow Cytometry; Gene Expression; Humans; Hydroxyurea; Indoles; Male; Neutrophils; Prostaglandins E; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2007 |
Bursts of potential elicited by d-amphetamine in central snail neuron: effect of sodium azide.
Topics: Action Potentials; Animals; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dextroamphetamine; Estrenes; Ganglia, Invertebrate; Indoles; Intracellular Space; Neomycin; Neurons; Patch-Clamp Techniques; Pyrroles; Pyrrolidinones; Snails; Sodium Azide | 2007 |
Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats.
Topics: Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Proteins; Hyperalgesia; Immunoblotting; Indoles; Male; Morphine; Nifedipine; Polymerase Chain Reaction; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord | 2008 |
The cyclic AMP-dependent protein kinase A pathway is involved in progesterone effects on calcitonin secretion from TT cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blotting, Western; Calcitonin; Carbazoles; Cell Line, Tumor; Cell Nucleus; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression; Humans; Indoles; Mifepristone; Progesterone; Progestins; Pyrroles; Receptors, Progesterone; RNA, Messenger; Signal Transduction; Time Factors | 2007 |
Antithrombin inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression.
Topics: Antithrombins; Carbazoles; Cell Survival; Early Growth Response Protein 1; Epoprostenol; Extracellular Signal-Regulated MAP Kinases; Heparin; Humans; Indoles; Lipopolysaccharides; Models, Biological; Monocytes; Phosphorylation; Platelet Aggregation Inhibitors; Pyrroles; Tumor Necrosis Factor-alpha | 2008 |
Tonic protein kinase A activity maintains inactive beta2 integrins in unstimulated neutrophils by reducing myosin light-chain phosphorylation: role of myosin light-chain kinase and Rho kinase.
Topics: Adult; Carbazoles; CD18 Antigens; Cell Adhesion; Cyclic AMP-Dependent Protein Kinases; Homeostasis; Humans; Indoles; Myosin-Light-Chain Kinase; Neutrophils; Oligopeptides; Phosphorylation; Pyrroles; rho-Associated Kinases | 2008 |
Mechanisms underlying the long-term regulation of NHE3 by parathyroid hormone.
Topics: Animals; Biotinylation; Carbazoles; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Indoles; Kidney; Luciferases; Opossums; Parathyroid Hormone; Plasmids; Promoter Regions, Genetic; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2008 |
Memantine increases brain production of kynurenic acid via protein kinase A-dependent mechanism.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Carbazoles; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Male; Memantine; Neurons; Piperidines; Pyrroles; Rats; Rats, Wistar | 2008 |
Mechanisms of neuromodulation as dissected using Sr2+ at motor nerve endings.
Topics: 4-Aminopyridine; Amifampridine; Animals; Calcium; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Evoked Potentials; In Vitro Techniques; Nerve Endings; Neuromuscular Junction; Neurotransmitter Agents; Potassium Channel Blockers; Pyrroles; Ranidae; Statistics, Nonparametric; Strontium; Thionucleotides | 2008 |
GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220.
Topics: A Kinase Anchor Proteins; Amyloid beta-Peptides; Animals; Apoptosis; Carbazoles; Cells, Cultured; Crotonates; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GABA Agonists; GABA Antagonists; Hippocampus; Isoquinolines; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Peptide Fragments; Phosphinic Acids; Phosphorylation; Protein Kinase Inhibitors; Protein Subunits; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Signal Transduction; Sulfonamides | 2008 |
Cilostazol promotes survival of axotomized retinal ganglion cells in adult rats.
Topics: Animals; Axotomy; Carbazoles; Cell Survival; Cilostazol; Cyclodextrins; Dose-Response Relationship, Drug; Drug Interactions; Male; Optic Nerve Injuries; Phosphodiesterase Inhibitors; Pyrroles; Rats; Rats, Wistar; Retinal Ganglion Cells; Stilbamidines; Tetrazoles | 2008 |
Modulation of Na+-H+ exchange isoforms NHE1 and NHE3 by insulin-like growth factor-1 in isolated bovine articular chondrocytes.
Topics: Animals; Benzophenanthridines; Carbazoles; Cartilage, Articular; Cation Transport Proteins; Cattle; Cells, Cultured; Chondrocytes; Cycloheximide; Drug Combinations; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrostatic Pressure; Insulin-Like Growth Factor I; Male; Osmotic Pressure; Protein Synthesis Inhibitors; Pyrroles; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2008 |
Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists.
Topics: Adenylyl Cyclases; Adrenomedullin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Carbazoles; Cell Membrane; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; Kinetics; Ligands; Protein Kinase C; Pyrroles; Receptors, Calcitonin Gene-Related Peptide; Sulfonamides | 2008 |
Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.
Topics: Carbazoles; Catalytic Domain; Cell Line; Cell Proliferation; Collagen Type I; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Fibroblasts; Guanine Nucleotide Exchange Factors; Humans; Lung; Protein Kinase C-delta; Pyrroles; rap1 GTP-Binding Proteins | 2008 |
Protein kinase A modulates retinal ganglion cell growth during development.
Topics: Animals; Animals, Newborn; Carbazoles; Cells, Cultured; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Mesocricetus; Mice; Pyrroles; Retinal Ganglion Cells | 2008 |
Prostacyclin analogs stimulate VEGF production from human lung fibroblasts in culture.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adult; Carbazoles; Cell Culture Techniques; Cells, Cultured; Epoprostenol; Fibroblasts; Humans; Iloprost; Lung; Prostaglandins I; Pyrroles; RNA, Messenger; Stimulation, Chemical; Vascular Endothelial Growth Factor A | 2008 |
Beta-adrenergic receptor activation during distinct patterns of stimulation critically modulates the PKA-dependence of LTP in the mouse hippocampus.
Topics: Adrenergic beta-Agonists; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Female; Hippocampus; Intracellular Signaling Peptides and Proteins; Isoproterenol; Locus Coeruleus; Long-Term Potentiation; Memory; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Nerve Net; Neuronal Plasticity; Pyrroles; Receptors, Adrenergic, beta; RGS Proteins; Synaptic Transmission | 2008 |
Down-regulation of histamine H1 receptors by beta2-adrenoceptor-mediated inhibition of H1 receptor gene transcription.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Astrocytoma; Carbazoles; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Fenoterol; Humans; Promoter Regions, Genetic; Pyrroles; Receptors, Histamine H1; RNA Stability; RNA, Messenger; Transcription, Genetic | 2008 |
Chemokine CXCL8 modulates GluR1 phosphorylation.
Topics: Animals; Animals, Newborn; Calcium; Carbazoles; Cells, Cultured; Cerebellum; Chelating Agents; Chemotaxis; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Humans; Interleukin-8; Mutation; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors; Transfection | 2008 |
Activation of exchange protein activated by cyclic-AMP enhances long-lasting synaptic potentiation in the hippocampus.
Topics: Animals; Butadienes; Carbazoles; Cyclic AMP; Dactinomycin; Emetine; Extracellular Signal-Regulated MAP Kinases; Female; Guanine Nucleotide Exchange Factors; Hippocampus; Isoproterenol; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Synaptic Transmission; Transcription, Genetic | 2008 |
d-Amphetamine inhibits inwardly rectifying potassium channels in Xenopus oocytes expression system.
Topics: Animals; Carbazoles; Dextroamphetamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Female; Isoquinolines; Membrane Potentials; Microinjections; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Serine; Sulfonamides; Xenopus | 2008 |
AKAP150-anchored PKA activity is important for LTD during its induction phase.
Topics: A Kinase Anchor Proteins; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Gene Deletion; Hippocampus; Isoquinolines; Long-Term Synaptic Depression; Male; Mice; Pyrroles; Sulfonamides | 2008 |
PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior.
Topics: Amygdala; Animals; Arthritis; Behavior; Butadienes; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Indoles; Male; Maleimides; Neuronal Plasticity; Neurons; Nitriles; Pain; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thionucleotides | 2008 |
Resveratrol reverses ET-1-evoked mitogenic effects in human coronary arterial cells by activating the kinase-G to inhibit ERK-enzymes.
Topics: Antineoplastic Agents, Phytogenic; Carbazoles; Cell Division; Cells, Cultured; Coronary Vessels; Cyclic GMP-Dependent Protein Kinases; Drug Interactions; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogens; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Protein Kinase Inhibitors; Pyrroles; Resveratrol; Stilbenes | 2009 |
Ghrelin induces proliferation in human aortic endothelial cells via ERK1/2 and PI3K/Akt activation.
Topics: Adenine; Androstadienes; Aorta; Carbazoles; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Flavonoids; Ghrelin; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Wortmannin | 2008 |
Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.
Topics: alpha-Methyltyrosine; Animals; Antineoplastic Agents; Butyrates; Carbazoles; Cell Differentiation; Cell Line, Tumor; Cyclic CMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Neuroblastoma; Norepinephrine; Phenotype; Pyrroles; Tretinoin; Tyrosine 3-Monooxygenase | 2008 |
Dendroaspis natriuretic peptide relaxes gastric antral circular smooth muscle of guinea-pig through the cGMP/cGMP-dependent protein kinase pathway.
Topics: Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Elapid Venoms; Female; Guinea Pigs; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Muscle Relaxation; Muscle, Smooth; Patch-Clamp Techniques; Peptides; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Pyloric Antrum; Pyrroles; Signal Transduction | 2008 |
Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line.
Topics: Animals; Base Sequence; Brain Stem; Bucladesine; Carbazoles; Cell Line, Tumor; Colforsin; Conserved Sequence; Corticotropin-Releasing Hormone; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Promoter Regions, Genetic; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Relaxin; Sulfonamides | 2009 |
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aged; Antibodies; Carbazoles; Cells, Cultured; Chondrocytes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1beta; Isoquinolines; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Osteoarthritis; Prostaglandin D2; Pyrroles; Receptors, Immunologic; Receptors, Leukotriene B4; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Th2 Cells | 2008 |
Kinase-dependent modification of dendritic excitability after long-term potentiation.
Topics: Animals; Butadienes; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Flavonoids; In Vitro Techniques; Learning; Long-Term Potentiation; Male; Nitriles; Protein Kinase Inhibitors; Pyramidal Cells; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Role of 1alpha,25(OH)2 vitamin D3 on alpha-[1-(14)C]MeAIB accumulation in immature rat testis.
Topics: Age Factors; Animals; beta-Alanine; Bucladesine; Calcitriol; Carbazoles; Carbon Radioisotopes; Dose-Response Relationship, Drug; Intracellular Space; Ion Channels; Male; Protein Biosynthesis; Pyrroles; Rats; Rats, Wistar; Testis; Testosterone; Time Factors | 2009 |
Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Rapid component I(Kr) of cardiac delayed rectifier potassium currents in guinea-pig is inhibited by alpha(1)-adrenoreceptor activation via protein kinase A and protein kinase C-dependent pathways.
Topics: Animals; Benzophenanthridines; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Kinetics; Myocytes, Cardiac; Patch-Clamp Techniques; Phenylephrine; Potassium; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrroles; Receptors, Adrenergic, alpha-1 | 2009 |
Effects of Dendroaspis natriuretic peptide on delayed rectifier potassium currents and its mechanism.
Topics: Aminoquinolines; Animals; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Elapid Venoms; Electrophysiology; Enzyme Inhibitors; Female; Guinea Pigs; Intercellular Signaling Peptides and Proteins; Male; Patch-Clamp Techniques; Peptides; Potassium Channels, Voltage-Gated; Pyrroles; Signal Transduction | 2009 |
HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury.
Topics: Animals; Arginase; Axons; Blotting, Western; Carbazoles; Cell Line; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Ganglia, Spinal; Genetic Therapy; Genetic Vectors; Immunochemistry; Myelin Proteins; Nerve Tissue Proteins; Neurites; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Simplexvirus; Spinal Cord; Spinal Cord Injuries | 2009 |
Improvement of two-way active avoidance memory requires protein kinase a activation and brain-derived neurotrophic factor expression in the dorsal hippocampus.
Topics: Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Hippocampus; Memory; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sleep | 2009 |
beta-adrenergic enhancement of brain kynurenic acid production mediated via cAMP-related protein kinase A signaling.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic Agents; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; In Vitro Techniques; Kynurenic Acid; L-Lactate Dehydrogenase; Male; Neuroglia; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Thionucleotides; Transaminases | 2009 |
cAMP-dependent kinase does not modulate the Slack sodium-activated potassium channel.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Calcineurin; Carbazoles; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Kinetics; Membrane Potentials; Models, Genetic; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Sodium-Activated; Pyrroles; Rats; Transfection | 2009 |
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Apoptosis; Breast Neoplasms; Carbazoles; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Female; G1 Phase; Humans; Leptin; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction | 2009 |
Aqueous extract of Zanthoxylum schinifolium elicits contractile and secretory responses via beta1-adrenoceptor activation in beating rabbit atria.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Carbazoles; Cardiotonic Agents; Cardiovascular Agents; Cyclic AMP; Diltiazem; Heart Atria; Hemodynamics; Imidazoles; Plant Extracts; Plant Leaves; Plant Stems; Propanolamines; Propranolol; Pyrroles; Rabbits; Receptors, Adrenergic, beta-1; Stroke Volume; Zanthoxylum | 2009 |
Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78).
Topics: Adenylyl Cyclases; Calcineurin; Carbazoles; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Half-Life; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Muscle Proteins; Neurons; Protein Kinase Inhibitors; Protein Stability; Pyrroles; Sulfonamides | 2009 |
Arsenic trioxide modulates the central snail neuron action potential.
Topics: Action Potentials; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carbazoles; Estrenes; Neomycin; Neurons; Oxides; Pyrroles; Pyrrolidinones; Snails; Type C Phospholipases | 2009 |
The d5 dopamine receptor mediates large-conductance, calcium- and voltage-activated potassium channel activation in human coronary artery smooth muscle cells.
Topics: Carbazoles; Cells, Cultured; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Humans; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Myocytes, Smooth Muscle; Oligonucleotides, Antisense; Pyrroles; Receptors, Dopamine D1; Receptors, Dopamine D5 | 2010 |
Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration.
Topics: Animals; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinases; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Humans; Infant, Newborn; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Neoplasm Invasiveness; Phosphorylation; Pyrroles; Rats; Sodium Channels; Stromal Cells; Tetrodotoxin; Up-Regulation | 2010 |
Expression of thrombin-activatable fibrinolysis inhibitor (TAFI) is up-regulated by increase in intracellular cyclic AMP levels in cultured HepG2 cells.
Topics: Base Sequence; Bucladesine; Carbazoles; Carboxypeptidase B2; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; DNA Primers; Humans; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Signal Transduction; Transcription, Genetic; Transfection; Up-Regulation | 2009 |
cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes.
Topics: Animals; Calcium; Calcium-Binding Proteins; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Molsidomine; Muscle Cells; Myocytes, Cardiac; Okadaic Acid; Phosphorylation; Pyrroles | 2010 |
Effects of topical application of alpha-D-glucosylglycerol on dermal levels of insulin-like growth factor-i in mice and on facial skin elasticity in humans.
Topics: Administration, Topical; Animals; Capsaicin; Carbazoles; Dermis; Elasticity; Face; Female; Ganglia, Spinal; Genes; Glucosides; Humans; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons, Afferent; Pyrroles; RNA, Messenger; Sensory Receptor Cells; Skin; TRPV Cation Channels | 2010 |
Stimulation of Fc gammaRI on primary sensory neurons increases insulin-like growth factor-I production, thereby reducing reperfusion-induced renal injury in mice.
Topics: Acetophenones; Animals; Antibodies; Apoptosis; Calcitonin Gene-Related Peptide; Carbazoles; Caspase 3; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Immunoglobulin Fc Fragments; Immunoglobulin G; Insulin-Like Growth Factor I; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Phospholipase A2 Inhibitors; Phospholipases A2; Pyrroles; Receptors, IgG; Reperfusion Injury; Sensory Receptor Cells | 2010 |
Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A down-regulation in breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activators; Female; Humans; Leptin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; Signal Transduction; STAT3 Transcription Factor; Time Factors; Up-Regulation | 2010 |
Long-term potentiation of neuronal excitation in the central nucleus of the rat amygdala revealed by imaging with a voltage-sensitive dye.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Animals, Newborn; Anisomycin; Biophysics; Calcium; Carbazoles; Colforsin; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyrroles; Rats; Rats, Wistar; Time Factors; Valine; Voltage-Sensitive Dye Imaging | 2010 |
Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes.
Topics: Animals; Calcium; Calcium Channels; Carbazoles; Cell Shape; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ghrelin; Heart Ventricles; Homeostasis; Male; Membrane Potentials; Myocytes, Cardiac; Oligopeptides; Pyrroles; Rats; Rats, Wistar; Receptors, Ghrelin; Sarcomeres | 2010 |
Comparison of effects of protein kinase A, mitogen-activated protein kinase, and cyclin-dependent kinase blockers on rabbit ovarian granulosa cell functions.
Topics: Animals; Carbazoles; Cell Extracts; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinases; Female; Flavonoids; Granulosa Cells; Insulin-Like Growth Factor I; Kinetin; Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Pyrroles; Rabbits | 2010 |
Action potential bursts in central snail neurons elicited by paeonol: roles of ionic currents.
Topics: 4-Aminopyridine; Acetophenones; Action Potentials; Animals; Calcium; Carbazoles; Charybdotoxin; Electric Conductivity; Indoles; Ion Channels; Nervous System Physiological Phenomena; Neurons; Potassium; Pyrroles; Reaction Time; Snails; Tetraethylammonium | 2010 |
'Silent' priming of translation-dependent LTP by ß-adrenergic receptors involves phosphorylation and recruitment of AMPA receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Biophysics; Carbazoles; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Phosphorylation; Propranolol; Pyrroles; Receptors, Adrenergic, beta; Receptors, AMPA; Serine | 2010 |
Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer.
Topics: Adult; Aged; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Enzyme Activators; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prostaglandins E; Protein Kinase C; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Xanthones | 2011 |
Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: the role of water molecules examined.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Carbazoles; DNA Primers; Indoles; Kinetics; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphorylase Kinase; Pyrroles; Sequence Homology, Amino Acid; Staurosporine; Water | 2011 |
Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human (alpha)3(beta)4 nicotinic receptor.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiological Phenomena; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Receptor, Adenosine A2A; Receptors, Nicotinic; Signal Transduction; Superior Cervical Ganglion; Transfection; Triazoles | 2011 |
Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A.
Topics: 4-Aminopyridine; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbazoles; Cerebral Cortex; Clonazepam; Cyclic AMP-Dependent Protein Kinases; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Indoles; Isoquinolines; Macrolides; Male; Maleimides; Membrane Potentials; Nerve Endings; omega-Conotoxins; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sulfonamides; Synaptosomes; Thiazepines; Ubiquinone | 2011 |
cAMP response element-binding protein (CREB) is required for epidermal growth factor (EGF)-induced cell proliferation and serum response element activation in neural stem cells isolated from the forebrain subventricular zone of adult mice.
Topics: Animals; Blotting, Western; Carbazoles; Cell Growth Processes; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Female; Isoquinolines; Mice; Neural Stem Cells; Prosencephalon; Protein Kinase Inhibitors; Pyrroles; Serum Response Element; Sulfonamides; Transcriptional Activation | 2011 |
Dopamine D1 receptor signaling system regulates ryanodine receptor expression after intermittent exposure to methamphetamine in primary cultures of midbrain and cerebral cortical neurons.
Topics: Animals; Benzazepines; Carbazoles; Cells, Cultured; Central Nervous System Stimulants; Cerebral Cortex; Dactinomycin; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Mesencephalon; Methamphetamine; Mice; Neurons; Pregnancy; Protein Synthesis Inhibitors; Pyrroles; Quinpirole; Receptors, Dopamine D1; Ryanodine Receptor Calcium Release Channel; Signal Transduction | 2011 |
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
Topics: Analysis of Variance; Anilides; Animals; Ankyrins; Antineoplastic Agents, Phytogenic; Capsaicin; Carbazoles; Central Nervous System; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Oligopeptides; Paclitaxel; Pain Measurement; Physical Stimulation; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, PAR-2; Sulfonamides; Time Factors; TRPV Cation Channels; Tryptases; Type C Phospholipases | 2011 |
β₁-adrenergic receptor up-regulation induced by nadolol is mediated via signal transduction pathway coupled to α₁-adrenergic receptors.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Benzophenanthridines; Carbazoles; Cells, Cultured; Cerebral Cortex; Dopamine beta-Hydroxylase; Embryo, Mammalian; Enzyme Inhibitors; Mice; Mice, Inbred ICR; Nadolol; Neurons; Pyrroles; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Signal Transduction; Time Factors; Up-Regulation | 2011 |
EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals.
Topics: Animals; Carbazoles; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Flavonoids; Gastrointestinal Motility; Ileum; Isoxazoles; Lipopolysaccharides; Macrophages; Male; Mice; Nitric Oxide Synthase Type II; Pyrroles; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfones; Up-Regulation | 2012 |
Critical role for protein kinase A in the acquisition of gregarious behavior in the desert locust.
Topics: Animals; Behavior, Animal; Carbazoles; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Grasshoppers; Molecular Sequence Data; Protein Kinase Inhibitors; Pyrroles; RNA Interference | 2012 |
Dopaminergic modulation of ganglion-cell photoreceptors in rat.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Actins; Animals; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; In Vitro Techniques; Light; Light Signal Transduction; Male; Membrane Potentials; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Pyrroles; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Retina; Retinal Ganglion Cells; Rod Opsins; Sodium Channel Blockers; Tetrodotoxin; Visual Pathways | 2012 |
Involvement of protein kinase C in reduction of aggregated protein and phosphorylation of CREB in glomeruli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Cattle; CREB-Binding Protein; Cyclic AMP; Enzyme Inhibitors; Kidney Glomerulus; Male; Mice; Mice, Inbred ICR; Oxidative Phosphorylation; Protein Kinase C; Pyrroles; Serum Albumin, Bovine | 2012 |
Mps one binder 2 gene upregulation in the stellation of astrocytes induced by cAMP-dependent pathway.
Topics: Animals; Astrocytes; Blotting, Western; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fluorescent Antibody Technique; Nerve Tissue Proteins; Pyrroles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2012 |
Calcium and cAMP levels interact to determine attraction versus repulsion in axon guidance.
Topics: Animals; Animals, Newborn; Axons; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carbazoles; Cells, Cultured; Chemotaxis; Computer Simulation; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Growth Cones; Models, Neurological; Myelin-Associated Glycoprotein; Nerve Growth Factor; Neurites; Neurons; Potassium; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Superior Cervical Ganglion; Thionucleotides | 2012 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
cAMP prevents TNF-induced apoptosis through inhibiting DISC complex formation in rat hepatocytes.
Topics: Animals; Apoptosis; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Death Domain Receptor Signaling Adaptor Proteins; Hepatocytes; Pyrroles; Rats; Tumor Necrosis Factor-alpha | 2012 |
Dopamine D1 receptors regulate type 1 inositol 1,4,5-trisphosphate receptor expression via both AP-1- and NFATc4-mediated transcriptional processes.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blotting, Western; Calcineurin; Calcium Signaling; Carbazoles; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Chromatin Immunoprecipitation; Cyclic AMP; Dopamine Agonists; Enzyme Inhibitors; Immunohistochemistry; Inositol 1,4,5-Trisphosphate Receptors; Mice; Microscopy, Fluorescence; Neurons; NFATC Transcription Factors; Pyrroles; Receptors, Dopamine D1; Signal Transduction; Transcription Factor AP-1; Transcription, Genetic | 2012 |
Inhibition of thimet oligopeptidase by siRNA alters specific intracellular peptides and potentiates isoproterenol signal transduction.
Topics: Amino Acid Sequence; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Genes, Reporter; HEK293 Cells; Humans; Isoproterenol; Luciferases; Metalloendopeptidases; Peptides; Protein Kinase Inhibitors; Pyrroles; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties.
Topics: Actins; Brain; Capillary Permeability; Carbazoles; Cells, Cultured; Cilostazol; Claudin-5; Dipyridamole; Drug Interactions; Electric Impedance; Endothelial Cells; Histamine; Humans; Isoquinolines; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Pyrroles; Rolipram; Sulfonamides; Tetrazoles | 2012 |
14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing.
Topics: 14-3-3 Proteins; Amino Acids; Analysis of Variance; Animals; Axons; Bacterial Proteins; Basic Helix-Loop-Helix Transcription Factors; beta-Galactosidase; Carbazoles; Cells, Cultured; Chemotaxis; Chickens; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Electroporation; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Hedgehog Proteins; Kruppel-Like Transcription Factors; Luminescent Proteins; Mice; Mice, Transgenic; Neurons; Piperazines; Pregnancy; Protein Isoforms; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Simplexvirus; Spinal Cord Injuries; Time Factors; Wnt1 Protein; Zinc Finger Protein Gli2 | 2012 |
Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Signaling; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Evaluation, Preclinical; Guanine Nucleotide Exchange Factors; Heart Ventricles; Isoproterenol; Male; Myocytes, Cardiac; Potassium; Pyrroles; Rats; Rats, Wistar | 2013 |
Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Carbazoles; Cations, Divalent; Cerebral Arteries; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Endothelium, Vascular; Female; Gene Expression Regulation; Isoproterenol; Nickel; Nifedipine; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability.
Topics: Action Potentials; Animals; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Ganglia, Spinal; Male; Neurons; Protein Kinase Inhibitors; Pyrroles; Rabbits | 2013 |
Inosine induces presynaptic inhibition of acetylcholine release by activation of A3 adenosine receptors at the mouse neuromuscular junction.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Carbazoles; Diaphragm; Dihydropyridines; Ethylmaleimide; Female; Inosine; Male; Mice; Neuromuscular Junction; Phrenic Nerve; Pyrroles; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2013 |
Spinal 5-HT7 receptors and protein kinase A constrain intermittent hypoxia-induced phrenic long-term facilitation.
Topics: Animals; Arterial Pressure; Blood Gas Analysis; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Enzyme Inhibitors; Hypoglossal Nerve; Hypoxia; Injections, Spinal; Long-Term Potentiation; Male; NADPH Oxidases; Phenols; Phrenic Nerve; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, G-Protein-Coupled; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Sulfonamides | 2013 |
The secretogranin II gene is a signal integrator of glutamate and dopamine inputs.
Topics: Animals; Bucladesine; Calcium; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dopamine; Extracellular Signal-Regulated MAP Kinases; Glutamine; Hippocampus; Ionomycin; Mice; Neuroglia; Neurons; Neurotransmitter Agents; Oligonucleotide Array Sequence Analysis; Pyrroles; RNA, Messenger; Secretogranin II; Signal Transduction | 2014 |
cAMP-PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3-Orai1 complex.
Topics: Adrenergic beta-Agonists; Azepines; Calcium; Calcium Channels; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Isoproterenol; Membrane Microdomains; Niacinamide; ORAI1 Protein; Phosphodiesterase 4 Inhibitors; Protein Binding; Protein Kinase Inhibitors; Pyrroles; Small-Conductance Calcium-Activated Potassium Channels | 2014 |
NMDA receptor activation and PKC but not PKA lead to the modification of the long-term potentiation in the insular cortex induced by conditioned taste aversion: differential role of kinases in metaplasticity.
Topics: Animals; Avoidance Learning; Benzophenanthridines; Carbazoles; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Long-Term Potentiation; Male; Piperazines; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Taste | 2014 |
Adrenomedullin increases the short-circuit current in the rat prostate: Receptors, chloride channels, the effects of cAMP and calcium ions and implications on fluid secretion.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium Channel Blockers; Calcium Channels; Carbazoles; Chloride Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Male; Nifedipine; ortho-Aminobenzoates; Peptide Fragments; Prostate; Pyrroles; Rats; Rats, Sprague-Dawley; Semen | 2014 |
Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection.
Topics: Animals; Carbazoles; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; GTP-Binding Proteins; Indoles; Protein Glutamine gamma Glutamyltransferase 2; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transglutaminases | 2014 |
Adrenomedullin increases the short-circuit current in the mouse seminal vesicle: actions on chloride secretion.
Topics: Adrenomedullin; Animals; Carbazoles; Chloride Channels; Chlorides; Cyclic AMP-Dependent Protein Kinases; Electrophysiological Phenomena; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; ortho-Aminobenzoates; Pyrroles; Seminal Vesicles | 2014 |
Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety.
Topics: Adenosine; Amygdala; Animals; Anxiety; Brain; Carbazoles; Caspase 1; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Exploratory Behavior; Feeding Behavior; Glyburide; Interleukin-1beta; Ion Transport; KATP Channels; Locomotion; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Potassium; Pyrroles; Receptor, Adenosine A2A; Receptors, Interleukin-1 Type I | 2014 |
Pregabalin activates ROMK1 channels via cAMP-dependent protein kinase and protein kinase C.
Topics: Analgesics; Animals; Anticonvulsants; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Female; gamma-Aminobutyric Acid; Isoquinolines; Oocytes; Potassium Channels, Inwardly Rectifying; Pregabalin; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Sulfonamides; Xenopus laevis | 2014 |
Central vagal afferent endings mediate reduction of food intake by melanocortin-3/4 receptor agonist.
Topics: alpha-MSH; Animals; Carbazoles; Eating; Male; Microinjections; Nerve Endings; Neurons, Afferent; Nodose Ganglion; Peptides, Cyclic; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Rats; Receptor, Melanocortin, Type 4; Solitary Nucleus; Synapsins; Vagus Nerve | 2014 |
Zeta inhibitory peptide (ZIP) erases long-term memories in a cockroach.
Topics: Animals; Benzophenanthridines; Carbazoles; Cell-Penetrating Peptides; Cockroaches; Conditioning, Psychological; Lipopeptides; Memory, Long-Term; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyrroles | 2015 |
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons.
Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones | 2015 |
Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.
Topics: Animals; Brain Neoplasms; Carbazoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Female; Glioblastoma; HEK293 Cells; Humans; Isoquinolines; Mice; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyrroles; rac GTP-Binding Proteins; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Sulfonamides | 2015 |
β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amrinone; Animals; Arrhythmias, Cardiac; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Electric Stimulation; Electrocardiography; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guinea Pigs; Heart Failure; In Vitro Techniques; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Pyrroles; Receptors, Adrenergic, beta-2; Thionucleotides; Ventricular Function | 2015 |
Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B.
Topics: A Kinase Anchor Proteins; Adenylyl Cyclases; Animals; Calcineurin; Carbazoles; Caveolae; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Ion Channel Gating; Isoproterenol; Male; Mesenteric Arteries; Myocytes, Smooth Muscle; Potassium Channels, Voltage-Gated; Pyrroles; Rats, Wistar | 2015 |
Cyclic Adenosine Monophosphate-Mediated Enhancement of Vascular Endothelial Growth Factor Released by Differentiated Human Monocytic Cells: The Role of Protein Kinase A.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Albuterol; Atenolol; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Ethanolamines; Humans; Isoproterenol; Lipopolysaccharides; Macrophages; Procaterol; Pyrroles; Vascular Endothelial Growth Factor A | 2015 |
Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol.
Topics: Animals; Atrial Function, Right; Calcium Signaling; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Glucagon; Heart Atria; Heart Rate; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Myocardium; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2015 |
Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying Mechanisms.
Topics: Animals; Carbazoles; CCAAT-Enhancer-Binding Protein-beta; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystathionine gamma-Lyase; Gluconeogenesis; Glucose; Hepatocytes; Hydrogen Sulfide; Liver; Mice; Mice, Knockout; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pyrroles; Receptors, Glucocorticoid; Transcription Factors | 2016 |
Persistent Associative Plasticity at an Identified Synapse Underlying Classical Conditioning Becomes Labile with Short-Term Homosynaptic Activation.
Topics: Animals; Aplysia; Benzophenanthridines; Biophysics; Carbazoles; Cells, Cultured; Conditioning, Classical; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; FMRFamide; Ganglia, Sensory; Long-Term Potentiation; Nerve Net; Patch-Clamp Techniques; Pyrroles; Sensory Receptor Cells; Serotonin; Synapses; Time Factors | 2015 |
mGlu1 receptor mediates homeostatic control of intrinsic excitability through Ih in cerebellar Purkinje cells.
Topics: Action Potentials; Animals; Carbazoles; Chromones; Cyclic AMP-Dependent Protein Kinases; Homeostasis; Naphthalenes; Neuronal Plasticity; Purkinje Cells; Pyrroles; Rats; Receptors, Metabotropic Glutamate; Tetrodotoxin | 2016 |
An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons.
Topics: Alprostadil; Animals; Carbazoles; Dinoprostone; In Vitro Techniques; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Male; Methyl Ethers; Mice; Mice, Inbred C57BL; Pyrroles; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2016 |
Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes, Beige; Adipocytes, Brown; Carbazoles; Cell Differentiation; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Gene Expression Regulation; Humans; Indomethacin; Insulin; Mesenchymal Stem Cells; Mitochondria; Primary Cell Culture; Pyrroles; RNA, Small Interfering; Triiodothyronine | 2016 |
Activation of adenylate cyclase-cyclic AMP-protein kinase A signaling by corticotropin-releasing factor within the dorsolateral bed nucleus of the stria terminalis is involved in pain-induced aversion.
Topics: Adenylyl Cyclases; Animals; Carbazoles; Colforsin; Conditioning, Classical; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Male; Pain; Pyrroles; Rats; Rats, Sprague-Dawley; Septal Nuclei; Signal Transduction | 2016 |
Orexin-A Protects Human Neuroblastoma SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Neurotoxicity: Involvement of PKC and PI3K Signaling Pathways.
Topics: Benzophenanthridines; Calcium; Carbazoles; Cell Line, Tumor; Cell Survival; Chromones; Cyclooxygenase 2; HSP70 Heat-Shock Proteins; Humans; Intracellular Space; Membrane Potential, Mitochondrial; Morpholines; Neuroblastoma; Neuroprotective Agents; Neurotoxins; NF-E2-Related Factor 2; Orexin Receptors; Orexins; Oxidopamine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Signal Transduction | 2017 |
Inhibition of cAMP-Dependent PKA Activates β2-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A2 via Raf-1/MEK/ERK and IP3-Dependent Ca2+ Signaling in Atrial Myocytes.
Topics: Animals; Calcium Signaling; Carbazoles; Cats; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Female; Group IV Phospholipases A2; Heart Atria; Inositol 1,4,5-Trisphosphate Receptors; Male; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Proto-Oncogene Proteins c-raf; Pyrroles; Receptors, Adrenergic, beta-2; Signal Transduction | 2016 |
Calcitriol (1,25-dihydroxyvitamin D
Topics: Animals; Calcitriol; Calcium Channels, L-Type; Calcium Signaling; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitation Contraction Coupling; Mice; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Pyrroles; Receptors, Calcitriol | 2017 |
Effects of baicalin on alveolar fluid clearance and α-ENaC expression in rats with LPS-induced acute lung injury.
Topics: Acute Lung Injury; Adenylyl Cyclase Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Edema; Epithelial Cells; Epithelial Sodium Channels; Flavonoids; Ionomycin; Lipopolysaccharides; Lung; Male; Mice; Protein Kinase Inhibitors; Pyrroles; Rats; Water | 2017 |
Noradrenergic β-Adrenoceptor-Mediated Intracellular Molecular Mechanism of Na-K ATPase Subunit Expression in C6 Cells.
Topics: Animals; Carbazoles; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Intracellular Fluid; Protein Subunits; Pyrroles; Rats; Receptors, Adrenergic, beta; Sodium; Sodium-Potassium-Exchanging ATPase | 2018 |
Participation of Antidiuretic Hormone (ADH) in Asthma Exacerbations Induced by Psychological Stress via PKA/PKC Signal Pathway in Airway-Related Vagal Preganglionic Neurons (AVPNs).
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Asthma; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cytokines; Disease Models, Animal; Eosinophils; Female; Mice; Mice, Inbred BALB C; Morpholines; Neurons; Ovalbumin; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Receptors, Vasopressin; Signal Transduction; Spiro Compounds; Stress, Psychological; Vasopressins | 2017 |
Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophysiological Phenomena; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Models, Molecular; Molecular Docking Simulation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Peptide Fragments; Protein Kinase Inhibitors; Pyrroles; Rats, Wistar; Sulfonamides; Tail; Vasodilation | 2017 |
Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability.
Topics: Adenylyl Cyclases; Animals; Carbazoles; Clathrin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endosomes; Flavonoids; Guinea Pigs; Heart; Humans; MAP Kinase Signaling System; Myocardium; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrroles; Receptors, G-Protein-Coupled; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I | 2017 |
Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms.
Topics: Animals; Aorta, Abdominal; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Hyperhomocysteinemia; In Vitro Techniques; Male; Molecular Docking Simulation; Oligopeptides; Protein Kinase Inhibitors; Pyrroles; Rabbits; Signal Transduction; Vascular Diseases | 2017 |
Broad-spectrum protein kinase inhibition by the staurosporine analog KT-5720 reverses ethanol withdrawal-associated loss of NeuN/Fox-3.
Topics: Animals; Antigens, Nuclear; Carbazoles; DNA-Binding Proteins; Ethanol; Hippocampus; Nerve Tissue Proteins; Nuclear Proteins; Organ Culture Techniques; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Staurosporine; Substance Withdrawal Syndrome | 2017 |
Prostaglandin E1 protects hepatocytes against endoplasmic reticulum stress-induced apoptosis via protein kinase A-dependent induction of glucose-regulated protein 78 expression.
Topics: Alprostadil; Apoptosis; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; Humans; Isoquinolines; Phosphorylation; Pyrroles; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfonamides; Thapsigargin; Transcription Factor CHOP; Unfolded Protein Response; X-Box Binding Protein 1 | 2017 |
Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adolescent; Adult; Animals; Baclofen; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Drug Resistant Epilepsy; Enzyme Inhibitors; Epilepsy; Epilepsy, Temporal Lobe; Female; GABA-B Receptor Agonists; Humans; Inhibitory Postsynaptic Potentials; Male; Middle Aged; Muscarinic Agonists; Neocortex; Patch-Clamp Techniques; Pertussis Toxin; Pilocarpine; Protein Kinase C; Pyramidal Cells; Pyrroles; Rats; Receptors, GABA-A; Receptors, GABA-B; Temporal Lobe | 2018 |
Effects of Nitric Oxide on Voltage-Gated K⁺ Currents in Human Cardiac Fibroblasts through the Protein Kinase G and Protein Kinase A Pathways but Not through S-Nitrosylation.
Topics: Action Potentials; Adenine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Myofibroblasts; Nitric Oxide; Oxadiazoles; Potassium Channels, Voltage-Gated; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine | 2018 |
Expression of Concentrative Nucleoside Transporters ( SLC28A) in the Human Placenta: Effects of Gestation Age and Prototype Differentiation-Affecting Agents.
Topics: Carbazoles; Cell Differentiation; Cell Line, Tumor; Equilibrative Nucleoside Transport Proteins; Female; Gene Expression Regulation, Developmental; Gestational Age; Humans; Membrane Transport Proteins; Placenta; Pregnancy; Pyrroles; RNA, Messenger; Up-Regulation | 2018 |
Effects of nitric oxide on apoptosis and voltage-gated calcium channels in human cardiac myofibroblasts.
Topics: Apoptosis; Calcium Channels; Carbazoles; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Fibroblasts; Guanylate Cyclase; Humans; Myofibroblasts; Nitric Oxide; Nitric Oxide Donors; Pyrroles; Signal Transduction | 2020 |