Page last updated: 2024-08-18

pyrroles and kb 3022

pyrroles has been researched along with kb 3022 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Awata, N; Nakada, Y; Shimada, H1
Akimoto, K; Hanamori, M; Mizuno, T; Nakagawa, H1
Awata, N; Ikuta, Y; Kawashima, T; Nakada, Y1
Obata, Y; Oda, M; Yamamoto, N; Yokota, K2
Oda, M; Yamashita, A; Yokota, K1
Oda, M; Yamamoto, N; Yamashita, A; Yokota, K2
Morimoto, Y; Oda, M; Yamamoto, N; Yamashita, A; Yokota, K1
Oda, M; Yamamoto, N; Yamashita, A; Yokota, K; Yoshidomi, M1
Matsuo, K; Oda, M; Yamashita, A; Yokota, K1
Kondo, K; Nakashima, M; Shimazawa, M; Takiguchi, Y; Umemura, K1

Other Studies

12 other study(ies) available for pyrroles and kb 3022

ArticleYear
[Determination of the main metabolite (desethyl KBT-3022) of a new antiplatelet agent, KBT-3022 in plasma by gas chromatography].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992, Volume: 112, Issue:6

    Topics: Administration, Oral; Animals; Chromatography, Gas; Dogs; Platelet Aggregation Inhibitors; Pyrroles; Thiazoles

1992
Photo-stability of the new antiplatelet agent, KBT-3022 (ethyl 2-[4,5-bis(4-methoxyphenyl)thiazole-2-yl]pyrrol-1-ylacetate) in aqueous solutions containing acetonitrile.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:11

    Topics: Acetonitriles; Drug Stability; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Light; Platelet Aggregation Inhibitors; Pyrroles; Spectrophotometry, Ultraviolet; Temperature; Thiazoles

1992
Determination of the antiplatelet agent. KB-3022, and its metabolite by high-performance liquid chromatography.
    Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Humans; Male; Platelet Aggregation Inhibitors; Pyrroles; Rats; Rats, Inbred Strains; Thiazoles

1990
Inhibitory effect of KBT-3022, a new anti-platelet agent, on infiltration of polymorphonuclear leukocytes induced by leukotriene B4 or formyl-methionyl-leucyl-phenylalanine in mice.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:3

    Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Indomethacin; Leukocytes; Leukotriene B4; Mice; Mice, Inbred Strains; N-Formylmethionine Leucyl-Phenylalanine; Platelet Aggregation Inhibitors; Pyrroles; Thiazoles

1995
Anti-thrombotic activity of KBT-3022 in experimental models of thrombosis.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:2

    Topics: Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Extracorporeal Circulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Mice; Mice, Inbred Strains; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Silver Nitrate; Thiazoles; Thrombosis; Ticlopidine

1995
The effects of KBT-3022, a new anti-platelet agent, on hemorheological properties in guinea pigs.
    Thrombosis and haemostasis, 1995, Volume: 73, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Aspirin; Blood Viscosity; Diphosphoglyceric Acids; Drug Evaluation, Preclinical; Erythrocyte Deformability; Fibrinogen; Guinea Pigs; Hematocrit; Hemorheology; Pentoxifylline; Plasma; Platelet Aggregation Inhibitors; Pyrroles; Thiazoles; Ticlopidine

1995
Effect of KBT-3022, a new diphenylthiazole derivative, on platelet functions.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Edema; Erythema; Gastric Mucosa; Guinea Pigs; Humans; Mice; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Rats; Serotonin; Species Specificity; Thiazoles; Thrombin; Ultraviolet Rays

1995
Effect of KBT-3022, a new cyclooxygenase inhibitor, on experimental brain edema in vitro and in vivo.
    European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3

    Topics: Animals; Arachidonic Acid; Aspirin; Brain; Brain Edema; Brain Ischemia; Cyclooxygenase Inhibitors; Gerbillinae; Guinea Pigs; In Vitro Techniques; Indomethacin; Lipid Peroxidation; Male; Pyrroles; Thiazoles

1996
Protective effect of KBT-3022, a new cyclooxygenase inhibitor, in cerebral hypoxia and ischemia.
    Japanese journal of pharmacology, 1995, Volume: 69, Issue:4

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hypoxia; Male; Mice; Pyrroles; Thiazoles

1995
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine

1996
The mechanism of action of KBT-3022, a new antiplatelet agent.
    General pharmacology, 1997, Volume: 28, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acid; Blood Platelets; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Guinea Pigs; In Vitro Techniques; Intramolecular Oxidoreductases; Isomerases; Male; Phosphatidic Acids; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rabbits; Thiazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase

1997
Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022.
    European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3

    Topics: Animals; Aspirin; Femoral Artery; Light; Male; Phenylacetates; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Thiazoles; Thrombosis

1997