pyrroles has been researched along with cs 0777 in 8 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (12.50) | 29.6817 |
2010's | 7 (87.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Carrothers, TJ; Inaba, S; Moberly, JB; Rohatagi, S; Shimozato, T; Truitt, KE; Zahir, H | 1 |
Hsu, C; Moberly, JB; Noveck, RJ; Rohatagi, S; Truitt, KE; Zahir, H | 1 |
Honda, T; Inaba, S; Kubota, K; Matsuoka, T; Nara, F; Tamura, M; Watanabe, N; Yahara, C; Yonesu, K | 1 |
Chen, S; Ford, DM; Moberly, JB; Mochizuki, T; Truitt, KE; Vollmer, TL; Zahir, H | 1 |
Inaba, S; Kubota, K; Sakurai, H; Shinagawa, A; Takanaka, K | 1 |
Goto, M; Ikeda, T; Inaba, S; Iwabuchi, H; Izumi, T; Takahashi, M; Tanaka, H | 1 |
Doi-Komuro, H; Goto, M; Inaba, SI; Inoue, R; Izumi, T; Kagari, T; Oshima, K; Shimozato, T; Tanaka, H; Tanaka-Takanaka, K; Tomisato, W; Yuita, H | 1 |
Inaba, SI; Izumi, T; Kubota, K; Sakurai, H; Tanaka-Takanaka, K; Yamaguchi-Goto, M; Yonesu, K | 1 |
2 trial(s) available for pyrroles and cs 0777
Article | Year |
---|---|
Use of an exposure-response model to aid early drug development of an oral sphingosine 1-phosphate receptor modulator.
Topics: Administration, Oral; Adolescent; Adult; Amino Alcohols; CD4-Positive T-Lymphocytes; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lymphocyte Count; Lymphocyte Subsets; Lymphocytes; Lysophospholipids; Male; Middle Aged; Models, Biological; Prodrugs; Pyrroles; Receptors, Lysosphingolipid; Sphingosine; Young Adult | 2009 |
Pharmacological modulation of peripheral T and B lymphocytes by a selective sphingosine 1-phosphate receptor-1 modulator.
Topics: Adult; Amino Alcohols; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lymphocyte Count; Male; Pyrroles; Receptors, Lysosphingolipid; Young Adult | 2012 |
6 other study(ies) available for pyrroles and cs 0777
Article | Year |
---|---|
Purification and identification of activating enzymes of CS-0777, a selective sphingosine 1-phosphate receptor 1 modulator, in erythrocytes.
Topics: Amino Alcohols; Animals; Enzyme Inhibitors; Erythrocytes; Fructose; HEK293 Cells; Humans; Morpholines; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Prodrugs; Pyrroles; Rats; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors | 2011 |
Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: results from a 12-week, open-label pilot study in multiple sclerosis patients.
Topics: Administration, Oral; Amino Alcohols; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Immunologic; Down-Regulation; Humans; Lymphocyte Subsets; Lymphopenia; Lysophospholipids; Multiple Sclerosis; Pilot Projects; Pyrroles; Receptors, Lysosphingolipid; Sphingosine | 2012 |
Identification of a metabolizing enzyme in human kidney by proteomic correlation profiling.
Topics: Alkaline Phosphatase; Amino Alcohols; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Isoenzymes; Kidney; Propylene Glycols; Proteomics; Pyrroles; Sphingosine | 2013 |
Pharmacokinetics and disposition of CS-0777, a sphingosine 1-phosphate receptor modulator, in rats and monkeys.
Topics: Administration, Oral; Algorithms; Amino Alcohols; Animals; Biotransformation; Feces; Hydroxylation; Injections, Intravenous; Intestinal Absorption; Macaca fascicularis; Male; Oxidation-Reduction; Phosphorylation; Protein Binding; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Tissue Distribution | 2015 |
Evaluation of species difference in peripheral lymphocyte reduction effect of CS-0777, a sphingosine 1-phosphate receptor modulator, based on a pharmacokinetic/pharmacodynamic model analysis.
Topics: Administration, Oral; Amino Alcohols; Animals; Dose-Response Relationship, Drug; Female; Lymphocytes; Macaca fascicularis; Male; Pyrroles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Lysosphingolipid; Species Specificity | 2016 |
Enzymatic kinetics regarding reversible metabolism of CS-0777, a sphingosine 1-phosphate receptor modulator, via phosphorylation and dephosphorylation in humans.
Topics: Alkaline Phosphatase; Amino Alcohols; Enzyme Inhibitors; Erythrocytes; Female; Fructose; Humans; Intestine, Small; Kidney; Kinetics; Levamisole; Male; Microsomes, Liver; Morpholines; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Pyrroles; Receptors, Lysosphingolipid; Recombinant Proteins | 2018 |