pyrroles has been researched along with azd3241 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergman, L; Farde, L; Halldin, C; Johnström, P; Malmquist, J; Varnäs, K | 1 |
| Amini, N; Budd, S; Cselényi, Z; Farde, L; Halldin, C; Helin, S; Johnström, P; Jucaite, A; Kirjavainen, A; Kugler, AR; Minkwitz, M; Posener, JA; Rinne, JO; Svenningsson, P; Varnäs, K; Varrone, A | 1 |
| Georgievska, B; Kaindlstorfer, C; Kugler, AR; Mather, RJ; Poewe, W; Sommer, P; Stefanova, N; Wenning, GK | 1 |
| Al-Huniti, N; Li, J; Li, Y; Mullen, JA; Savage, A; Taylor, W; Tong, X; Xu, H; Zhou, D | 1 |
1 trial(s) available for pyrroles and azd3241
| Article | Year |
|---|---|
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Follow-Up Studies; Humans; Male; Microglia; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Protein Binding; Pyrimidines; Pyrimidinones; Pyrroles; Receptors, GABA; Severity of Illness Index | 2015 |
3 other study(ies) available for pyrroles and azd3241
| Article | Year |
|---|---|
Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing.
Topics: Animals; Brain; Carbon Radioisotopes; Dose-Response Relationship, Radiation; Female; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Peroxidase; Positron-Emission Tomography; Pyrimidinones; Pyrroles; Radiopharmaceuticals | 2015 |
Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications.
Topics: alpha-Synuclein; Animals; Brain; Disease Models, Animal; Enzyme Inhibitors; Humans; Male; Mice, Transgenic; Microglia; Motor Activity; Multiple System Atrophy; Myelin Proteolipid Protein; Neurons; Neuroprotective Agents; Nitro Compounds; Peroxidase; Propionates; Pyrimidinones; Pyrroles; Severity of Illness Index; Treatment Outcome | 2015 |
Population Pharmacokinetic Modeling With Enterohepatic Circulation for AZD3241 in Healthy Subjects and Patients With Multiple System Atrophy.
Topics: Adult; Aged; Bile; Enterohepatic Circulation; Female; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Multiple System Atrophy; Peroxidase; Pyrimidinones; Pyrroles; Random Allocation | 2018 |