Page last updated: 2024-08-18

pyrroles and abt-737

pyrroles has been researched along with abt-737 in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (16.13)29.6817
2010's26 (83.87)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shore, GC; Viallet, J1
Andreeff, M; Bornmann, W; Contractor, R; Estrov, Z; Harris, D; Kantarjian, H; Konopleva, M; Samudio, I; Tsao, T; Viallet, J; Watt, J1
Azmi, AS; Mohammad, RM1
Kang, MH; Reynolds, CP1
Letai, A; Ni Chonghaile, T1
Acoca, S; Cui, Q; Purisima, EO; Shore, GC1
Bollard, CM; Buglio, D; Derenzini, E; Illés, A; Ji, Y; Jóna, A; Khaskhely, N; Medeiros, LJ; Shafer, JA; Younes, A1
Huang, DC; Khaw, SL; Roberts, AW1
Armeanu-Ebinger, S; Ellerkamp, V; Fuchs, J; Kirchner, B; Lieber, J; Warmann, SW; Wenz, J1
Amin, S; Awwad, A; Cheng, C; Daughdrill, G; Dewey, A; Doi, K; Krishnegowda, G; Li, R; Liu, X; Liu, Y; Loughran, TP; Manieri, W; Qin, Y; Schonbrunn, E; Sebti, S; Sung, SS; Wang, HG; Wu, H1
Al-Harbi, S; Almasan, A; Choudhary, GS; Mazumder, S1
Davids, MS; Letai, A1
Chang, X; Liu, Y; Shen, X; Song, T; Zhang, Z1
Arcaro, A; Bodmer, N; Cwiek, P; Djonov, V; Ghosal, A; Gross, N; Höland, K; Largey, F; Lucia Buccarello, A; Salm, F; Schäfer, SC; Styp-Rekowska, B; Westermann, F; Wotzkow, C; Zlobec, I1
Armeanu-Ebinger, S; Dewerth, A; Fuchs, J; Hoh, A; Lieber, J; Vogt, F1
Li, X; Shen, X; Song, T; Xue, Z; Zhang, Z1
Abesada, G; Belgnaoui, SM; Beljanski, V; Ben Yebdri, F; Brown, D; Goulet, ML; Haddad, EK; He, Z; Hiscott, J; Nichols, C; Richards, S; Samuel, S; Shamy, A; Steel, C; Van Grevenynghe, J1
Amin, S; Doi, K; Gowda, K; Pandey, MK; Sharma, AK; Wang, HG1
Armeanu-Ebinger, S; Ellerkamp, V; Fuchs, J; Lieber, J; Vogt, F; Warmann, SW; Wenz, J1
Croft, A; Farrelly, ML; Hersey, P; Jiang, CC; Wroblewski, D; Zhang, XD1
Amin, S; Barth, BM; Claxton, D; Doi, K; Gowda, K; Liu, Q; Loughran, TP; Wang, HG1
Bharti, A; Chipuk, JE; Elkholi, R; Renault, TT1
Elssner, C; Jaeger, D; Kautz, N; Koehler, BC; Lorenz, S; Scherr, AL; Schulze-Bergkamen, H; Urbanik, T; Welte, S1
Armeanu-Ebinger, S; Fuchs, J; Lieber, J1
Abusneina, A; Clément, J; Gauthier, ER; Harnett, CC1
Elssner, C; Jaeger, D; Jassowicz, A; Kautz, N; Koehler, BC; Lorenz, S; Radhakrishnan, P; Scherr, AL; Schneider, M; Schulze-Bergkamen, H; Weiss, J1
Cerchietti, L; Dupont, T; Hatzi, K; Leonard, J; Malik, A; Martin, P; Melnick, A; Patel, J; Tam, W; Yang, SN1
Becher-Boveleth, N; Broecker-Preuss, M; Mann, K1
Mazur, L; Opydo-Chanek, M1
Almeida, A; Fujita, M; Lambert, K; Lu, Y; Luo, Y; Mukherjee, N; Norris, DA; Robinson, SE; Robinson, WA; Shellman, YG; Shiau, CW; Su, JC1
Carroll, SL; Gibson, LM; Graham, CD; Kaza, N; Klocke, BJ; Pruitt, HC; Roth, KA; Shevde, LA1

Reviews

6 review(s) available for pyrroles and abt-737

ArticleYear
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy.
    Journal of cellular physiology, 2009, Volume: 218, Issue:1

    Topics: Aniline Compounds; Animals; Apoptosis; Benzamides; Binding Sites; Biphenyl Compounds; Gossypol; Humans; Indoles; Lymphoma; Models, Molecular; Neoplasms; Nitrophenols; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Sulfones

2009
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Feb-15, Volume: 15, Issue:4

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Gossypol; Humans; Indoles; Mitochondria; Neoplasms; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Thionucleotides

2009
Mimicking the BH3 domain to kill cancer cells.
    Oncogene, 2008, Volume: 27 Suppl 1

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Binding, Competitive; Biphenyl Compounds; Clinical Trials as Topic; Dimerization; Drug Delivery Systems; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indoles; Mice; Mitochondria; Multigene Family; Neoplasm Proteins; Neoplasms; Nitrophenols; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Structure-Activity Relationship; Sulfonamides; Sulfones; Thionucleotides

2008
Overcoming blocks in apoptosis with BH3-mimetic therapy in haematological malignancies.
    Pathology, 2011, Volume: 43, Issue:6

    Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Hematologic Neoplasms; Humans; Indoles; Molecular Mimicry; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides

2011
Targeting the B-cell lymphoma/leukemia 2 family in cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Sep-01, Volume: 30, Issue:25

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Drug Resistance, Neoplasm; Humans; Indoles; Molecular Targeted Therapy; Neoplasms; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Thionucleotides; Treatment Outcome

2012
The role of BH3-mimetic drugs in the treatment of pediatric hepatoblastoma.
    International journal of molecular sciences, 2015, Feb-16, Volume: 16, Issue:2

    Topics: Antibodies, Monoclonal; Apoptosis; Biphenyl Compounds; Child; Drug Resistance, Neoplasm; Hepatoblastoma; Humans; Indoles; Liver Neoplasms; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand

2015

Other Studies

25 other study(ies) available for pyrroles and abt-737

ArticleYear
Modulating the bcl-2 family of apoptosis suppressors for potential therapeutic benefit in cancer.
    Hematology. American Society of Hematology. Education Program, 2005

    Topics: Animals; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Genes, myc; Humans; Indoles; Models, Animal; Neoplasms; Nitrophenols; Oncogenes; Piperazines; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Pyrroles; Sulfonamides

2005
Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
    Cancer research, 2008, May-01, Volume: 68, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; AraC Transcription Factor; Biomimetics; Biphenyl Compounds; Cells, Cultured; Drug Synergism; HL-60 Cells; Humans; Indoles; Leukemia; Mice; Mice, Knockout; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nitrophenols; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Tumor Stem Cell Assay; U937 Cells

2008
Molecular dynamics study of small molecule inhibitors of the Bcl-2 family.
    Proteins, 2011, Volume: 79, Issue:9

    Topics: Alanine; Amino Acid Sequence; Biphenyl Compounds; Humans; Indoles; Molecular Conformation; Molecular Dynamics Simulation; Molecular Sequence Data; Nitrophenols; Piperazines; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sequence Alignment; Sulfonamides; Thermodynamics

2011
The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitors.
    Experimental hematology, 2011, Volume: 39, Issue:10

    Topics: Acetylation; Apoptosis; Apoptosis Regulatory Proteins; Benzamides; Biphenyl Compounds; Boronic Acids; Bortezomib; Cyclin-Dependent Kinase Inhibitor p21; Deoxycytidine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Hodgkin Disease; Humans; Indoles; Lymphoma, Non-Hodgkin; Neoplasm Proteins; Nitrophenols; Piperazines; Protein Processing, Post-Translational; Pyrazines; Pyridines; Pyrroles; Sulfonamides; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein

2011
Apoptosis sensitizers enhance cytotoxicity in hepatoblastoma cells.
    Pediatric surgery international, 2012, Volume: 28, Issue:2

    Topics: Apoptosis; Benzamides; Benzopyrans; Biphenyl Compounds; Blotting, Western; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Hepatoblastoma; Humans; Indoles; Liver Neoplasms; Nitriles; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Sulfones; Tumor Cells, Cultured

2012
Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation.
    The Journal of biological chemistry, 2012, Mar-23, Volume: 287, Issue:13

    Topics: Animals; bcl-X Protein; Biphenyl Compounds; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Jurkat Cells; K562 Cells; Leukemia; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides

2012
Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells.
    Cancer research, 2012, Jun-15, Volume: 72, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biphenyl Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Gossypol; Humans; Indoles; Leukemia, B-Cell; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Phosphorylation; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; RNA Interference; RNA, Small Interfering; Sulfonamides

2012
S1, a novel pan-BH3 mimetic, induces apoptosis in Mcl-1-overexpressing cells through Bak.
    Journal of pharmacological sciences, 2012, Volume: 119, Issue:4

    Topics: Acenaphthenes; Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Biphenyl Compounds; Cell Line, Tumor; Humans; Mice; Mice, Inbred BALB C; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Tumor Burden; Xenograft Model Antitumor Assays

2012
RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.
    Oncogene, 2013, Aug-22, Volume: 32, Issue:34

    Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Biphenyl Compounds; Blotting, Western; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Enzyme Activation; Fibroblast Growth Factor 2; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Nitrophenols; Oligonucleotide Array Sequence Analysis; Piperazines; Protein Kinase C-delta; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Receptor, Fibroblast Growth Factor, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sulfonamides

2013
BH3 mimetics reduce adhesion and migration of hepatoblastoma and hepatocellular carcinoma cells.
    Experimental cell research, 2013, Jun-10, Volume: 319, Issue:10

    Topics: Actins; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Caspase Inhibitors; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Movement; Cytoskeleton; Enzyme Activation; Fluorescent Antibody Technique; Hepatoblastoma; Humans; Indoles; Neoplasm Metastasis; Nitrophenols; Oligopeptides; Piperazines; Proteolysis; Pseudopodia; Pyrroles; Sulfonamides

2013
Pan-BH3 mimetic S1 exhibits broad-spectrum antitumour effects by cooperation between Bax and Bak.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:3

    Topics: Acenaphthenes; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Biphenyl Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Protein Binding; Pyrroles; RNA, Small Interfering; Sulfonamides

2013
BCL-2 inhibitors sensitize therapy-resistant chronic lymphocytic leukemia cells to VSV oncolysis.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2013, Volume: 21, Issue:7

    Topics: Animals; Biphenyl Compounds; Blotting, Western; Cell Line, Tumor; Cell Survival; Cells, Cultured; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoprecipitation; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Nitrophenols; Oncolytic Viruses; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Vesicular stomatitis Indiana virus

2013
Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biphenyl Compounds; Caspases; Cell Line, Tumor; Cell Survival; Drug Synergism; Drug Therapy, Combination; Epithelial Cells; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Inhibitory Concentration 50; Membrane Proteins; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins; Pyrroles; Signal Transduction; Skin; Sulfonamides

2013
BH3-mimetic drugs prevent tumour onset in an orthotopic mouse model of hepatoblastoma.
    Experimental cell research, 2014, Mar-10, Volume: 322, Issue:1

    Topics: Animals; Biomimetic Materials; Biphenyl Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatoblastoma; Humans; Indoles; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Nude; Mice, Transgenic; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Pyrroles; Sulfonamides

2014
OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Biphenyl Compounds; Calcium; Cell Line, Tumor; Cytosol; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Humans; Indoles; Melanoma; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Unfolded Protein Response; Up-Regulation

2013
Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression.
    Cancer biology & therapy, 2014, Volume: 15, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Bone Marrow Cells; Cell Line, Tumor; Coculture Techniques; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; Heterografts; Humans; Leukemia, Myeloid, Acute; Male; Mice, Inbred C57BL; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Pyrroles; RNA Interference; Stromal Cells; Sulfonamides

2014
B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.
    The Journal of biological chemistry, 2014, Sep-19, Volume: 289, Issue:38

    Topics: Aniline Compounds; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; bcl-X Protein; Benzamides; Benzopyrans; BH3 Interacting Domain Death Agonist Protein; Biphenyl Compounds; HeLa Cells; Humans; Indoles; Membrane Proteins; Mice; Mitochondria, Liver; Mitochondrial Membranes; Molecular Mimicry; Myeloid Cell Leukemia Sequence 1 Protein; Nitriles; Nitrophenols; Permeability; Piperazines; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins; Pyrroles; Sulfonamides; Sulfones; Unilamellar Liposomes

2014
Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cadherins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Indoles; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides

2014
Inhibition of MCL-1 by obatoclax sensitizes Sp2/0-Ag14 hybridoma cells to glutamine deprivation-induced apoptosis.
    Cell biochemistry and function, 2015, Volume: 33, Issue:5

    Topics: Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Glutamine; Humans; Hybridomas; Indoles; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sensitivity and Specificity; Sulfonamides

2015
Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.
    BMC cancer, 2015, Nov-19, Volume: 15

    Topics: Antineoplastic Agents; Autophagy; Biphenyl Compounds; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Indoles; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction; Sulfonamides

2015
Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: Animals; Biphenyl Compounds; Blotting, Western; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; Male; Mice; Mice, Nude; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-bcl-6; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Cell Death Induction by the Indirubin Derivative 7BIO and the BH3 Mimetic Drugs ABT-737 and GX15-070 in Medullary Thyroid Carcinoma Cells.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2016, Volume: 124, Issue:5

    Topics: BH3 Interacting Domain Death Agonist Protein; Biphenyl Compounds; Carcinoma, Neuroendocrine; Cell Death; Cell Line, Tumor; Humans; Indoles; Molecular Mimicry; Nitrophenols; Piperazines; Protein Kinase Inhibitors; Pyrroles; Sulfonamides; Thyroid Neoplasms

2016
Comparison of in vitro antileukemic activity of obatoclax and ABT-737.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Flow Cytometry; Humans; Indoles; Leukemia; Nitrophenols; Piperazines; Pyrroles; Sulfonamides

2016
Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.
    Oncotarget, 2017, Jul-18, Volume: 8, Issue:29

    Topics: Animals; Antineoplastic Agents; Bcl-2-Like Protein 11; Biphenyl Compounds; Cell Line, Tumor; Cell Self Renewal; Cell Survival; Disease Models, Animal; Drug Synergism; Female; Gene Knockout Techniques; Humans; Melanocytes; Melanoma; Mice; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Neoplastic Stem Cells; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Xenograft Model Antitumor Assays

2017
BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Line, Tumor; Chemokine CXCL12; Down-Regulation; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Indoles; Molecular Mimicry; Neurilemmoma; Nitrophenols; Piperazines; Poly (ADP-Ribose) Polymerase-1; Protein Binding; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides

2017