pyrroles has been researched along with abt-199 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Billard, C | 1 |
| Anderson, MA; Huang, D; Roberts, A | 1 |
| Andrews, DW; Brauer, PM; Hariharan, S; Leber, B; Oakes, CC; Oppermann, S; Shi, Y; Spaner, DE; Ylanko, J; Zúñiga-Pflücker, JC | 1 |
| Davids, MS; Lampson, BL | 1 |
| Cook, SJ; Gilley, R; Sale, MJ; Stuart, K | 1 |
| Anantram, A; Degani, M | 1 |
| Carter, MJ; Cox, KL; Cragg, MS; Cummin, TEC; Dunning, L; English, VL; Fell, R; Johnson, PWM; Ma, Y; Murray, TD; Packham, G; Powell, B; Turaj, AH | 1 |
| Albert, DH; Bellin, RJ; Boyiadzis, M; Bui, MH; Cai, T; Cavazos, A; Dorritie, KA; Faivre, EJ; Feng, W; Ferguson, DC; Goodwin, NC; Han, L; Hessler, P; Huang, X; Kati, WM; Konopleva, M; Kuruvilla, VM; Lam, LT; Lin, X; Lu, X; Magoc, TJ; McDaniel, KF; Mehta, G; Plotnik, JP; Rowe, J; Shanmugavelandy, SS; Shen, Y; Uziel, T; Zha, Z; Zhang, L; Zhang, Q | 1 |
5 review(s) available for pyrroles and abt-199
| Article | Year |
|---|---|
BH3 mimetics: status of the field and new developments.
Topics: Amino Acid Motifs; Aniline Compounds; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Drug Design; Drug Screening Assays, Antitumor; Gossypol; Humans; Indoles; Molecular Mimicry; Neoplasms; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides | 2013 |
Targeting BCL2 for the treatment of lymphoid malignancies.
Topics: Aniline Compounds; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Gossypol; Hematologic Neoplasms; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides | 2014 |
The Development and Current Use of BCL-2 Inhibitors for the Treatment of Chronic Lymphocytic Leukemia.
Topics: Aniline Compounds; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Gossypol; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Neutropenia; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides; Thionucleotides | 2017 |
Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.
Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bridged Bicyclo Compounds, Heterocyclic; Drug Screening Assays, Antitumor; Humans; Indoles; MAP Kinase Signaling System; Mitochondrial Dynamics; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Oncogene Addiction; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides | 2017 |
Targeting cancer's Achilles' heel: role of BCL-2 inhibitors in cellular senescence and apoptosis.
Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Arylsulfonates; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; Cell Line, Tumor; Cellular Senescence; Drug Screening Assays, Antitumor; Gene Expression Regulation; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxyquinolines; Indoles; Molecular Structure; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Protein Conformation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrogallol; Pyrroles; Salicylates; Structure-Activity Relationship; Sulfonamides | 2019 |
3 other study(ies) available for pyrroles and abt-199
| Article | Year |
|---|---|
High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells.
Topics: Adenine; bcl-X Protein; Bridged Bicyclo Compounds, Heterocyclic; Cellular Microenvironment; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Humans; Imaging, Three-Dimensional; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Mutation; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Quinazolinones; Reproducibility of Results; Signal Transduction; Stromal Cells; Sulfonamides; Sunitinib; Up-Regulation | 2016 |
BET inhibitors synergize with venetoclax to induce apoptosis in MYC-driven lymphomas with high BCL-2 expression.
Topics: Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Mice; Nerve Tissue Proteins; Oxazoles; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Pyridines; Pyrroles; Receptors, Cell Surface; Sulfonamides | 2020 |
Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |