prazosin and morphine
prazosin has been researched along with morphine in 50 studies
Research
Studies (50)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.00) | 18.7374 |
| 1990's | 9 (18.00) | 18.2507 |
| 2000's | 21 (42.00) | 29.6817 |
| 2010's | 6 (12.00) | 24.3611 |
| 2020's | 1 (2.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Figliozzi, GM; Goff, DA; Kerr, JM; Martin, EJ; Shoemaker, KR; Siani, MA; Simon, RJ; Spellmeyer, DC; Stauber, GB; Zuckermann, RN | 1 |
| Brasili, L; Di Toro, R; Giannella, M; Melchiorre, C; Piergentili, A; Pigini, M; Quaglia, W; Rossetti, L; Spampinato, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Avery, BA; Behnke, M; Chear, NJ; Hiranita, T; Kamble, SH; León, F; McCurdy, CR; McMahon, LR; Obeng, S; Patel, A; Ramanathan, S; Reeves, ME; Restrepo, LF; Sharma, A | 1 |
| Jansen van't Land, C; van der Laan, JW | 1 |
| Gebhart, GF; Zhuo, M | 1 |
| Grohs, JG; Huber, S; Raberger, G | 1 |
| Ansuategui, M; Feria, M; Naharro, L | 1 |
| Cascio, CS; Dallman, MF; Darlington, DN; Shinsako, J; Suemaru, S | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Simonato, M; Spalluto, P; Tanganelli, S; Tomasini, C | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Gregor, L; Thornhill, JA; Townsend, C | 1 |
| James, RC; Roberts, SM; Skoulis, NP | 1 |
| Buckingham, JC; Cooper, TA | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Rando, S; Simonato, M; Tanganelli, S | 1 |
| Reny-Palasse, V; Rips, R | 1 |
| Miller, D; Robblee, JA | 1 |
| Hirota, N; Kuraishi, Y; Satoh, M; Sugimoto, M; Takagi, H | 1 |
| Aleixandre, MA; García de Jalón, PD; Martin, MI | 1 |
| Alcaraz, C; Martinez-Piñero, MG; Milanés, MV; Vargas, ML | 1 |
| Gibert-Rahola, J; Maldonado, R; Micó, JA; Valverde, O | 1 |
| Fang, F; Proudfit, HK | 1 |
| Abysique, A; Bouvier, M; Orsoni, P | 1 |
| Cruz, SL; Rodríguez-Manzo, G | 1 |
| Laorden, ML; Milanés, MV | 1 |
| Chen, JY; Dafny, N; Kang, YM; Ouyang, W; Qiao, JT | 1 |
| Goto, T; Ochi, T | 1 |
| Adachi, YU; Satoh, T; Taoda, M; Uchihashi, Y; Vizi, ES; Watanabe, K | 1 |
| Blanc, G; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Blanc, G; Cotecchia, S; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Lähdesmäki, J; Ozdoğan, UK; Scheinin, M | 1 |
| Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV | 1 |
| Dang, VC; Williams, JT | 1 |
| Guo, YM; Jin, QY; Liang, C; Zhang, YR | 1 |
| Miranda, HF; Pinardi, G; Prieto, JC; Puig, MM | 1 |
| Climent, L; Horga, A; Horga, JF; Peiró, AM; Zapater, P | 1 |
Reviews
1 review(s) available for prazosin and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Other Studies
49 other study(ies) available for prazosin and morphine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Discovery of nanomolar ligands for 7-transmembrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Databases, Factual; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glycine; GTP-Binding Proteins; Ligands; Molecular Sequence Data; Molecular Structure; Oligopeptides; Peptoids; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Cell Surface; Receptors, Opioid, mu; Structure-Activity Relationship | 1994 |
1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (spipethiane), a potent and highly selective sigma1 ligand.
Topics: Animals; Guinea Pigs; Ligands; Piperidines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Structure-Activity Relationship | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Topics: Adrenergic Agents; Analgesics; Animals; Blood Proteins; CHO Cells; Cricetulus; Dopamine Agents; Guinea Pigs; Humans; Microsomes, Liver; Rats; Receptors, Adrenergic; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2020 |
Chronic infusion of clonidine does not alleviate spontaneous morphine withdrawal symptoms in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Doxazosin; Drug Implants; Eating; Food; Male; Morphine; Morphine Dependence; Motor Activity; Prazosin; Quinoxalines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1992 |
Tonic cholinergic inhibition of spinal mechanical transmission.
Topics: Animals; Biogenic Monoamines; Cholinergic Antagonists; Drug Interactions; Endorphins; Hot Temperature; Injections, Spinal; Male; Morphine; Naloxone; Pain Measurement; Parasympatholytics; Physical Stimulation; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic; Spinal Cord; Synaptic Transmission; Tail; Yohimbine | 1991 |
Cardiovascular and side effects of flesinoxan in conscious hypertensive dogs. Modulation by prazosin.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hypertension, Renal; Morphine; Pentobarbital; Physical Exertion; Piperazines; Prazosin; Sympatholytics | 1991 |
Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats.
Topics: Analgesics; Animals; Clomipramine; Endorphins; Female; Formaldehyde; Morphine; Naloxone; Norepinephrine; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Role of alpha-adrenergic mechanism in effects of morphine on the hypothalamo-pituitary-adrenocortical and cardiovascular systems in the rat.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Blood Pressure; Corticosterone; Heart Rate; Hypothalamo-Hypophyseal System; Male; Morphine; Pituitary-Adrenal System; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Yohimbine | 1989 |
Changes in cortical acetylcholine and gamma-aminobutyric acid outflow during morphine withdrawal involve alpha-1 and alpha-2 receptors.
Topics: Acetylcholine; Animals; Clonidine; Dioxanes; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Naloxone; Prazosin; Receptors, Adrenergic, alpha; Substance Withdrawal Syndrome | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
Intravenous morphine infusion (IMF) to drug-naive, conscious rats evokes bradycardic, hypotensive effects, but pressor actions are elicited after IMF to rats previously given morphine.
Topics: Animals; Atropine; Blood Pressure; Guanethidine; Heart Rate; Infusions, Intravenous; Male; Morphine; Naloxone; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Time Factors | 1989 |
A centrally-mediated effect of morphine to diminish hepatocellular glutathione.
Topics: Adrenalectomy; Animals; Epinephrine; Glutathione; Hydrocortisone; Injections, Intraventricular; Liver; Male; Mice; Mice, Inbred ICR; Morphine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1987 |
Interrelationships of opioidergic and adrenergic mechanisms controlling the secretion of corticotrophin releasing factor in the rat.
Topics: Adrenocorticotropic Hormone; alpha-Methyltyrosine; Animals; Blood Pressure; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; In Vitro Techniques; Male; Methyltyrosines; Morphine; Naloxone; Pituitary-Adrenal System; Prazosin; Rats; Rats, Inbred Strains | 1987 |
Inversion of the alpha-2 and alpha-1 noradrenergic control of the cortical release of acetylcholine and gamma-aminobutyric acid in morphine-tolerant guinea pigs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Clonidine; Dioxanes; Drug Tolerance; Female; gamma-Aminobutyric Acid; Guinea Pigs; Idazoxan; Locus Coeruleus; Male; Morphine; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha | 1988 |
Potentiation by TRH of the effect of imipramine on the forced-swimming test.
Topics: Animals; Drug Synergism; Drug Tolerance; Imipramine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone; Yohimbine | 1985 |
Perioperative management of a patient with a malignant pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; alpha-Methyltyrosine; Anesthesia, Epidural; Bone Cements; Femoral Neoplasms; Humans; Male; Methylmethacrylates; Methyltyrosines; Morphine; Pain, Postoperative; Pheochromocytoma; Prazosin; Preanesthetic Medication | 1985 |
Effects of morphine on noxious stimuli-induced release of substance P from rabbit dorsal horn in vivo.
Topics: Animals; Male; Methysergide; Morphine; Naloxone; Pain; Prazosin; Rabbits; Spinal Cord; Substance P | 1983 |
Changes in clonidine effect on longitudinal muscle-myenteric plexus strip preparation by morphine treatments.
Topics: Animals; Clonidine; Guinea Pigs; Morphine; Muscle, Smooth; Myenteric Plexus; Naloxone; Prazosin; Yohimbine | 1983 |
Catecholaminergic mediation of morphine-induced activation of pituitary-adrenocortical axis in the rat: implication of alpha- and beta-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Animals; Corticosterone; Corticotropin-Releasing Hormone; Dopamine; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Male; Morphine; Norepinephrine; Pituitary-Adrenal System; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reserpine | 1994 |
Study of the mechanisms involved in behavioral changes induced by flunitrazepam in morphine withdrawal.
Topics: Animals; Behavior, Animal; Dogs; Dose-Response Relationship, Drug; Flunitrazepam; Male; Mice; Mice, Inbred Strains; Morphine; Prazosin; Propranolol; Substance Withdrawal Syndrome | 1995 |
Antinociception produced by microinjection of morphine in the rat periaqueductal gray is enhanced in the foot, but not the tail, by intrathecal injection of alpha1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Behavior, Animal; Dioxanes; Female; Foot; Idazoxan; Injections, Spinal; Microinjections; Morphine; Narcotics; Nociceptors; Pain; Periaqueductal Gray; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spinal Cord; Tail | 1998 |
Evidence for supraspinal nervous control of external anal sphincter motility in the cat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anal Canal; Animals; Blood Pressure; Brimonidine Tartrate; Cats; Clonidine; Efferent Pathways; Electric Stimulation; Electromyography; Enkephalin, Leucine; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Locus Coeruleus; Male; Morphine; Narcotics; Nicergoline; Norepinephrine; Peripheral Nerves; Phenylephrine; Prazosin; Quinoxalines; Reflex; Spinal Cord | 1998 |
Gender differences in the cardiovascular responses to morphine and naloxone in spinal rats.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Prazosin; Rats; Rats, Wistar; Sex Factors; Spinal Cord | 2000 |
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catecholamines; Dopamine; Heart Ventricles; Male; Morphine; Morphine Dependence; Norepinephrine; Normetanephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
Norepinephrine modulates single hypothalamic arcuate neurons via alpha(1)and beta adrenergic receptors.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Cromakalim; Female; Glyburide; In Vitro Techniques; Locus Coeruleus; Magnesium; Male; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine | 2000 |
The antinociceptive effect of FR140423 in mice: involvement of spinal alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptors; Pain Measurement; Phentolamine; Prazosin; Propranolol; Pyrazoles; Receptors, Adrenergic, alpha-2; Spinal Cord; Sulfoxides; Yohimbine | 2000 |
Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of alpha2-adrenoceptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Berberine; Chromatography, High Pressure Liquid; Dexmedetomidine; Dose-Response Relationship, Drug; Feedback; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney Cortex; Male; Morphine; Norepinephrine; Piperazines; Prazosin; Prednisone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium | 2001 |
Cortical alpha 1-adrenergic regulation of acute and sensitized morphine locomotor effects.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Cerebral Cortex; Drug Administration Schedule; Injections, Intraperitoneal; Injections, Intraventricular; Male; Morphine; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2001 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
Influence of prazosin and clonidine on morphine analgesia, tolerance and withdrawal in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Pain; Prazosin; Substance Withdrawal Syndrome; Weight Loss | 2003 |
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine | 2003 |
Effects of imipramine on the expression and development of morphine dependence in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Gene Expression; Genes, fos; Heart Ventricles; Immunohistochemistry; Injections, Subcutaneous; Male; Morphine; Myocytes, Cardiac; Naloxone; Normetanephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Time Factors; Yohimbine | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
[Analysis of 37 drugs in whole blood by HPLC after solid phase extraction].
Topics: Chromatography, High Pressure Liquid; Doxapram; Doxepin; Estazolam; Forensic Medicine; Humans; Morphine; Papaverine; Pharmaceutical Preparations; Prazosin; Procaine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solvents | 2006 |
Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain.
Topics: Acetaminophen; Acute Disease; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Ketoprofen; Male; Mice; Morphine; Muscarinic Antagonists; Naltrexone; Narcotic Antagonists; Pain; Prazosin | 2008 |
Ketanserin potentiates morphine-induced antinociception mediated by kappa-receptor activation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Ketanserin; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Pain; Pain Measurement; Pain Threshold; Prazosin; Pyrrolidines; Receptors, Adrenergic, alpha-1; Receptors, Opioid, kappa; Receptors, Serotonin, 5-HT2; Serotonin Antagonists | 2011 |