prazosin and digoxin
prazosin has been researched along with digoxin in 39 studies
Research
Studies (39)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (46.15) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 7 (17.95) | 29.6817 |
| 2010's | 10 (25.64) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ebner, T; Ishiguro, N; Kishimoto, W; Schaefer, O; Shimizu, H | 1 |
| Balimane, PV; Frost, CE; Gan, J; Han, YH; He, K; Herbst, JJ; Humphreys, WG; Kolb, J; Shou, W; Wang, L; Zhang, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Atwell, RB | 1 |
| Ajayi, AA; Akintomide, AO; Osodi, OO | 1 |
| Guyatt, GH | 1 |
| Copur, S; Oram, E; Oto, A; Tokgözoğlu, L; Uğurlu, S | 1 |
| Halawa, B; Mazurek, W | 1 |
| Friedman, WF; George, BL | 1 |
| Gokhale, RD; Plunkett, LM; Tackett, RL; Vallner, JJ | 1 |
| Silke, B; Taylor, SH | 1 |
| Opie, LH | 1 |
| Plunkett, LM; Tackett, RL | 1 |
| Blaufox, MD; Lee, HB; Scharf, SC; Wexler, JP | 1 |
| Beekman, RH; Crowley, DC; Dick, M; Rocchini, AP; Rosenthal, A | 1 |
| Bertel, O | 1 |
| Gale, EV; Kuan, P; Reuben, SR; Wilde, PM | 1 |
| Chatterjee, K; Stern, L | 1 |
| Baglivo, HP; del Rio, M; Pujadas, G | 1 |
| Benzing, G; Dillon, TR; Janos, GG; Kaplan, S; Meyer, RA | 1 |
| Clarke, GM; Cope, GD; Hockings, BE; Taylor, RR | 1 |
| Fantini, F; Franchi, F; Michelucci, A; Morace, G; Porciani, MC | 1 |
| Takahashi, M; Uehara, Y | 1 |
| Kakumoto, M; Kobayashi, H; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Annaert, PP; Augustijns, PF; Baes, M; De Bruyn, T; Peeters, A; Sahi, J; Ye, ZW | 1 |
Reviews
2 review(s) available for prazosin and digoxin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The treatment of heart failure. A methodological review of the literature.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Diuretics; Heart Diseases; Humans; Hydralazine; Nitrates; Piperazines; Prazosin; Pyridines; Research Design | 1986 |
Trials
1 trial(s) available for prazosin and digoxin
| Article | Year |
|---|---|
The treatment of heart failure. A methodological review of the literature.
Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Diuretics; Heart Diseases; Humans; Hydralazine; Nitrates; Piperazines; Prazosin; Pyridines; Research Design | 1986 |
Other Studies
37 other study(ies) available for prazosin and digoxin
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Base Sequence; Dipeptidyl-Peptidase IV Inhibitors; DNA Primers; Drug Evaluation, Preclinical; Drug Interactions; HEK293 Cells; Humans; In Vitro Techniques; Linagliptin; LLC-PK1 Cells; Purines; Quinazolines; Swine | 2013 |
Characterization of efflux transporters involved in distribution and disposition of apixaban.
Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line, Transformed; Cell Membrane Permeability; Cyclosporine; Digoxin; Diketopiperazines; Dose-Response Relationship, Drug; Drug Interactions; Fibrinolytic Agents; Heterocyclic Compounds, 4 or More Rings; Humans; Ketoconazole; Male; Naproxen; Neoplasm Proteins; Pyrazoles; Pyridones; Rats | 2013 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
The use of alpha blockade in the treatment of congestive heart failure associated with dirofilariasis and mitral valvular incompetence.
Topics: Animals; Digoxin; Dirofilariasis; Dog Diseases; Dogs; Female; Furosemide; Heart Failure; Male; Mitral Valve Insufficiency; Prazosin; Quinazolines | 1979 |
The influence of captopril on intrahospital mortality and duration of hospitalization in Nigerians with congestive heart failure.
Topics: Captopril; Digoxin; Diuretics; Drug Therapy, Combination; Heart Failure; Hospital Mortality; Hospitals, State; Humans; Length of Stay; Nigeria; Prazosin; Retrospective Studies | 1992 |
Effects of oral prazosin on total plasma digoxin levels.
Topics: Administration, Oral; Adult; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Prazosin | 1988 |
[Interaction of digoxin with hydralazine and prazosin].
Topics: Adult; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Male; Middle Aged; Prazosin | 1986 |
Treatment of congestive heart failure by altering loading conditions of the heart.
Topics: Captopril; Cardiac Output; Child; Digoxin; Dopamine; Drug Therapy, Combination; Heart; Heart Failure; Humans; Hydralazine; Infant; Infant, Newborn; Nitroglycerin; Nitroprusside; Prazosin; Vasodilator Agents | 1985 |
Prazosin alters free and total plasma digoxin levels in dogs.
Topics: Animals; Digoxin; Dogs; Drug Interactions; Kinetics; Myocardial Contraction; Prazosin; Quinazolines; Radioimmunoassay | 1985 |
The pharmacokinetic, pharmacodynamic and haemodynamic effects of acute and chronic alpha-adrenoceptor blockade in chronic heart failure.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Digoxin; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Kinetics; Male; Middle Aged; Prazosin; Quinazolines | 1981 |
Calcium ions, drug action and the heart--with special reference to calcium antagonist drugs.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Catecholamines; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Digoxin; Drug Interactions; Heart; Heart Failure; Humans; Hypertension; Myocardial Contraction; Myocardial Infarction; Myocardium; Prazosin; Sinoatrial Node; Structure-Activity Relationship; Ventricular Fibrillation | 1984 |
Central alpha receptors and their role in digoxin cardiotoxicity.
Topics: Animals; Blood Pressure; Brain; Depression, Chemical; Digoxin; Dogs; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Male; Myocardial Contraction; Prazosin; Receptors, Adrenergic, alpha; Yohimbine | 1983 |
Pharmacologic alterations in Tc-99m binding by red blood cells: concise communication.
Topics: Animals; Blood Pressure; Captopril; Digoxin; Drug Interactions; Erythrocytes; Female; Hematocrit; Hypertension; Prazosin; Proline; Protein Binding; Quinazolines; Rats; Rats, Inbred Strains; Technetium; Time Factors | 1983 |
Vasodilator therapy in children: acute and chronic effects in children with left ventricular dysfunction or mitral regurgitation.
Topics: Adolescent; Captopril; Cardiac Catheterization; Child; Child, Preschool; Digoxin; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Hydralazine; Infant; Mitral Valve Insufficiency; Prazosin; Time Factors; Vasodilator Agents | 1984 |
[Current aspects of drug treatment of patients with congestive heart failure].
Topics: Blood Pressure; Digoxin; Diuretics; Heart Failure; Humans; Nitroglycerin; Prazosin; Vasodilator Agents | 1983 |
Haemodynamic effects of prazosin in CHF.
Topics: Cardiac Catheterization; Cardiac Output; Digoxin; Drug Therapy, Combination; Furosemide; Heart Failure; Hemodynamics; Humans; Prazosin; Quinazolines | 1981 |
Congestive cardiomyopathy: therapeutic approach.
Topics: Administration, Oral; Blood Pressure; Cardiac Output; Cardiomyopathies; Cardiotonic Agents; Digoxin; Heart Failure; Heart Rate; Hemodynamics; Humans; Prazosin; Vascular Resistance; Vasodilator Agents; Venous Pressure | 1982 |
[Usefulness of prazosin in the treatment of hypertensive patients with low cardiac output].
Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output, Low; Digoxin; Female; Heart Function Tests; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Prazosin; Vascular Resistance | 1980 |
Vasodilator therapy for congestive heart failure.
Topics: Adolescent; Adult; Child; Child, Preschool; Digoxin; Diuretics; Drug Therapy, Combination; Ferricyanides; Heart Failure; Humans; Infant; Nitroprusside; Prazosin; Quinazolines | 1980 |
Comparison of vasodilator drug prazosin with digoxin in aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Digoxin; Female; Hemodynamics; Humans; Male; Middle Aged; Prazosin; Quinazolines; Time Factors | 1980 |
[Evaluation of long-term treatment with isosorbide dinitrate and prazosin in cardiac insufficiency].
Topics: Adult; Aged; Digoxin; Drug Evaluation; Female; Furosemide; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Prazosin; Quinazolines; Time Factors | 1980 |
Hemodynamic changes during administration of drugs for mitral regurgitation in dogs.
Topics: Animals; Captopril; Cardiotonic Agents; Digoxin; Dog Diseases; Dogs; Echocardiography, Doppler, Color; Enalapril; Hemodynamics; Hydralazine; Mitral Valve Insufficiency; Prazosin; Vasodilator Agents | 1998 |
Effects of alpha-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport.
Topics: Adrenergic alpha-Antagonists; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Daunorubicin; Digoxin; Doxazosin; Drug Resistance, Multiple; HeLa Cells; Humans; Neoplasm Proteins; Prazosin; Vinblastine | 2009 |
Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
Topics: 1-Methyl-4-phenylpyridinium; Adolescent; Adult; Biological Transport; Corticosterone; Cryopreservation; Digoxin; Estradiol; Estrone; Hepatocytes; Humans; Male; Membrane Transport Proteins; Middle Aged; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 1; Prazosin; Rifampin; RNA, Messenger; Solute Carrier Organic Anion Transporter Family Member 1B3; Symporters; Taurocholic Acid | 2011 |