prazosin and cocaine
prazosin has been researched along with cocaine in 123 studies
Research
Studies (123)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (30.08) | 18.7374 |
| 1990's | 41 (33.33) | 18.2507 |
| 2000's | 30 (24.39) | 29.6817 |
| 2010's | 15 (12.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Doggrell, SA; Paton, DM | 1 |
| Goldberg, SR; Schindler, CW; Tella, SR | 1 |
| Branch, CA; Knuepfer, MM | 2 |
| Harris, GC; Hausken, ZE; Williams, JT | 1 |
| van Haaren, F | 1 |
| Berthold, CW; Gonzales, RA; Moerschbaecher, JM | 1 |
| Hitner, HW; Mahalik, MP | 1 |
| Bund, SJ; Heagerty, AM; Jagger, C; Stephens, N | 1 |
| Guimarães, S; Moura, D; Nunes, P; Pereira, O; Vaz-da Silva, MJ | 1 |
| Borowsky, B; Kuhn, CM | 1 |
| Malik, KU; Schwartz, DD | 1 |
| Chen, DG; Chen, RX; Li, JM; Xu, B; Zhang, L | 1 |
| Egashira, K; Morgan, JP; Morgan, KG | 1 |
| Gillis, RA; Ramwell, PW; Vargas, R | 1 |
| Foy, RA; Myles, JL; Wilkerson, RD | 1 |
| Burnstock, G; Ellis, JL; Kasakov, L; Vlaskovska, M | 1 |
| Aass, H; Osnes, JB; Skomedal, T | 1 |
| Hall, MT; Hamilton, CA; Kane, KA; Reid, JL; Rodger, IW; Wadsworth, RM | 1 |
| Andresen, MC; Nelson, SH; Steinsland, OS; Yang, M | 1 |
| Kurth, CD; Roth, RA; Wagerle, LC | 1 |
| Gonzales, RA; Moerschbaecher, JM; Mosaddeghi, M | 1 |
| Frenken, M | 1 |
| Kawasaki, H; Takasaki, K; Urabe, M | 1 |
| Broadley, KJ; Williamson, KL | 1 |
| Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Kamien, JB; Woolverton, WL | 1 |
| Pan, ZZ; Williams, JT | 1 |
| Bjellin, L; Edvinsson, L; Fallgren, B | 1 |
| Guimarães, S; Paiva, MQ; Polónia, JJ | 1 |
| Andersson, KE; Högestätt, ED; Skärby, T | 1 |
| Bradley, L; Doggrell, SA; Edmonds, SC | 1 |
| Andersson, RG; Grundström, N | 1 |
| Medgett, IC; Papanicolaou, M | 1 |
| Jeffries, WB; Pettinger, WA; Smyth, DD; Tam, LT; Wang, Y | 1 |
| Marshall, KC; Williams, JT | 1 |
| Allen, JM; McCarron, JG; McHale, NG; Thornbury, KD | 1 |
| Lafi, MA; Leake, LD | 1 |
| Rybarczyk, MC; Walland, A | 1 |
| Docherty, JR; Hyland, L | 1 |
| Barrett, JE; Tessel, RE | 1 |
| Woolverton, WL | 1 |
| Cohen, RA; Tesfamariam, B; Weisbrod, RM | 1 |
| Snoddy, AM; Tessel, RE | 1 |
| Russell, RD; Stripling, JS | 1 |
| Müller-Schweinitzer, E | 1 |
| Petersen, EN | 1 |
| Duval, N; Langer, SZ; Shepperson, NB | 1 |
| Kirpekar, SM | 1 |
| De Jonge, A; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B | 1 |
| Langer, SZ; Shepperson, NB | 1 |
| Chang, RS; Kling, P; Lotti, VJ | 1 |
| Elverdin, JC; Luchelli-Fortis, MA; Perec, CJ; Stefano, FJ | 1 |
| Kigoshi, S; Muramatsu, I; Oshita, M | 1 |
| Arnerić, SP; Barfknecht, CF; Long, JP; Mott, J; Roetker, A | 1 |
| De Mey, JG; Rusch, NJ; Vanhoutte, PM | 1 |
| Burt, RP; Chapple, CR; Marshall, I | 1 |
| Duckles, SP; Glenn, TC; Huang, SL | 1 |
| Alvarez, TA; Keller, PA; Konkol, RJ; Madden, JA | 1 |
| Billman, GE | 1 |
| Baim, DS; Carrozza, JP; Gladstone, S; Gordon, PC; Kuntz, RE; Miao, L; Morgan, JP; Núñez, BD; Ross, JN | 1 |
| Allen, JM; Hughes, GA | 1 |
| Albertson, TE; Derlet, RW; Tseng, CC | 1 |
| Andres, RL; Monga, M; Sanborn, BM; Weisbrodt, NW | 1 |
| Knuepfer, MM; Mueller, PJ | 1 |
| Lamas, JL; Spadari, RC | 1 |
| Chan, SH; Chang, AY; Chen, CF; Kuo, TB; Tsai, TH | 1 |
| El-Mas, MM; Elmallah, AI; Omar, AG; Sharabi, F | 1 |
| Ray, SM; Saunders, SS; Schoener, EP; Shivapuja, BG | 1 |
| Dehkordi, O; Dennis, GC; Millis, RM; Trouth, CO | 1 |
| Balster, RL; Gold, LH | 1 |
| Abrahams, TP; Liu, W; Varner, KJ | 1 |
| Kleven, MS; Koek, W | 1 |
| Angel, I; Deplanne, V; Palea, S | 1 |
| Betz, AL; Dombrowski, MP; Fomin, VP; Hurd, WW | 1 |
| Hayashi, N; Inagaki, R; Ishii, Y; Kunitomo, M; Muramatsu, I; Sakai, T; Shinozuka, K; Taniguchi, T | 1 |
| Kamenka, JM; Kleven, MS; Koek, W; Vignon, J | 1 |
| Conlee, RK; Hammer, RL; Kelly, KP; Ojuka, EO | 1 |
| Borda, E; Busch, L; Wald, M | 1 |
| Filip, M; Nowak, E; Papla, I | 1 |
| Blanc, G; Drouin, C; Glowinski, J; Tassin, JP; Villégier, AS | 1 |
| Blanc, G; Cotecchia, S; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Caló, G; Joyce, PI; Lambert, DG; Rizzi, D; Rowbotham, DJ | 1 |
| Bellinger, L; Cepeda-Benito, A; Ho, D; Nation, J; Wellman, P | 1 |
| Cleary, L; Docherty, JR; Vandeputte, C | 1 |
| Beemster, P; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Hillier, C; MacDonald, A; Zacharia, J | 1 |
| Platt, DM; Rowlett, JK; Spealman, RD | 2 |
| Dang, VC; Williams, JT | 1 |
| Auclair, A; Cotecchia, S; Drouin, C; Glowinski, J; Tassin, JP | 1 |
| Herndon, JG; Killiany, RJ; Luebke, JI; Moore, TL; Moss, MB; Rosene, DL; Schettler, SP | 1 |
| Kosten, TA; Zhang, XY | 2 |
| Dautreaux, B; Henry, JP; Isabelle, M; Monteil, C; Moritz, F; Mulder, P; Richard, V; Thuillez, C | 1 |
| Cao, N; Haynes, JM; Ventura, S | 1 |
| Feliu-Mojer, M; Jiménez-Rivera, CA; Vázquez-Torres, R | 1 |
| Berríos-Cartagena, N; González-Cabrera, S; Jiménez-Rivera, CA; Ortiz, JG; Rubio-Dávila, M; Silva, WI; Tirado-Costacamps, A; Vázquez-Torres, R | 1 |
| Kennedy, A; Peskind, ER; Raskind, MA; Tapp, AM | 1 |
| Baker, KE; Broadley, KJ; Herbert, AA | 1 |
| Fink, GD; Galligan, JJ; Park, J; Swain, GM | 1 |
| Freeman, KB; Riley, AL; Verendeev, A | 1 |
| Barbee, S; Clifford, PS; Elliott, AE; Hollas, CN; Nation, JR; Wellman, PJ | 1 |
| Berger, SP; Bernardi, RE; Lattal, KM; Ryabinin, AE | 1 |
| Bernardi, RE; Lattal, KM | 2 |
| Aston-Jones, G; Smith, RJ | 1 |
| Ecke, LE; Elmer, GI; Suto, N | 1 |
| Docherty, JR | 2 |
| Boughner, E; Cummins Jacklin, E; Kent, K; Kwiatkowski, D; Leri, F; MacDonald, T | 1 |
| Epstein, MP; Foster, SL; Pitts, EG; Schmidt, KT; Schroeder, JP; Smith, BM; Squires, K; Weinshenker, D | 1 |
| Dobrzański, G; Kwiatkowska, K; Pradel, K; Przewłocki, R; Solecki, WB; Szklarczyk, K | 1 |
| Barbosa-Méndez, S; Matus-Ortega, M; Salazar-Juárez, A | 1 |
| Grycel, K; Jiao, R; Khan, YM; Li, J; Liu, B; Song, R; Sun, X; Wang, L; Wang, Q; Wu, Q; Xu, Y; Zhang, B; Zhou, L; Zhou, Z; Zhu, F | 1 |
| Colomar, L; Font, L; López-Cruz, L; Luján, MA; Pastor, R; Tarragón, E | 1 |
Reviews
1 review(s) available for prazosin and cocaine
| Article | Year |
|---|---|
Support for a role for feedback regulation of norepinephrine release.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Cocaine; Cystamine; Diethylamines; Drug Synergism; Electric Stimulation; Ephedrine; Feedback; Naphthalenes; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Membranes | 1984 |
Other Studies
122 other study(ies) available for prazosin and cocaine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Effects of prazosin and phentolamine on responses to field stimulation and to noradrenaline in vas deferens and anococcygeus muscle of the rat.
Topics: Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Nortriptyline; Phentolamine; Prazosin; Quinazolines; Rats; Vas Deferens | 1978 |
Adrenoceptor mechanisms in the cardiovascular effects of cocaine in conscious squirrel monkeys.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cocaine; Heart Rate; Labetalol; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saimiri; Yohimbine | 1992 |
Adrenergic mechanisms underlying cardiac and vascular responses to cocaine in conscious rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cocaine; Dioxanes; Drug Interactions; Heart Rate; Idazoxan; Male; Metoprolol; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasodilation; Yohimbine | 1992 |
Cocaine induced synchronous oscillations in central noradrenergic neurons in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Evoked Potentials; Idazoxan; In Vitro Techniques; Kinetics; Kynurenic Acid; Locus Coeruleus; Male; Membrane Potentials; Neurons; Oscillometry; Picrotoxin; Prazosin; Rats; Rats, Wistar; Strychnine; Synapses | 1992 |
Effects of cocaine alone and in combination with prazosin or ondansetron on multiple fixed-interval fixed-ratio performance in pigeons.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Drug Interactions; Female; Food; Imidazoles; Male; Ondansetron; Prazosin; Reinforcement Schedule; Serotonin Antagonists | 1992 |
Prazosin attenuates the effects of cocaine on motor activity but not on schedule-controlled behavior in the rat.
Topics: Animals; Cocaine; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Male; Motor Activity; Prazosin; Rats; Reinforcement Schedule | 1992 |
Antagonism of cocaine-induced fetal anomalies by prazosin and diltiazem in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cocaine; Diltiazem; Dose-Response Relationship, Drug; Female; Fetal Resorption; Male; Mice; Organ Size; Prazosin; Pregnancy; Teratogens; Vasoconstriction | 1992 |
Arterial neuroeffector responses in early and mature spontaneously hypertensive rats.
Topics: Animals; Arteries; Cocaine; Electric Stimulation; Hypertension; Male; Neuroeffector Junction; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Involvement of alpha 1- and alpha 2-adrenoceptors in the responses of proximal and distal segments of the canine saphenous vein to exogenous and endogenous noradrenaline.
Topics: Animals; Cocaine; Dogs; Drug Interactions; Electric Stimulation; Female; Male; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Saphenous Vein; Tyramine; Vasoconstriction; Yohimbine | 1991 |
Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation.
Topics: Adrenocorticotropic Hormone; Animals; Biogenic Monoamines; Cocaine; Corticosterone; Dopamine; Dopamine Antagonists; Haloperidol; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Ketanserin; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Piperazines; Pituitary-Adrenal System; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stimulation, Chemical; Time Factors | 1991 |
Mechanism of neurotransmitter release elicited by the preferential alpha 1-adrenergic receptor agonist phenylephrine in superfused superior cervical ganglion cells in culture.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atenolol; Cells, Cultured; Cocaine; Cyclic AMP; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Ethanolamines; Ganglia, Sympathetic; Kidney; Methoxamine; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Potassium Chloride; Prazosin; Propranolol; Rats; Tritium | 1991 |
[Modulation of norepinephrine release in sympathetic nerve endings in renal hypertensive dogs].
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dioxanes; Dogs; Female; Hypertension, Renal; Idazoxan; Male; Nerve Endings; Norepinephrine; Prazosin; Sympathetic Nervous System; Tyramine | 1990 |
Effects of cocaine on excitation-contraction coupling of aortic smooth muscle from the ferret.
Topics: Adrenergic Fibers; Animals; Atropine; Calcium; Cocaine; Dose-Response Relationship, Drug; Endothelium, Vascular; Ferrets; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Reserpine | 1991 |
Propranolol promotes cocaine-induced spasm of porcine coronary artery.
Topics: Animals; Cocaine; Coronary Vessels; Drug Synergism; Isometric Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propranolol; Stereoisomerism; Swine; Vasoconstriction | 1991 |
Contraction of bovine coronary vascular smooth muscle induced by cocaine is not mediated by norepinephrine.
Topics: Animals; Arteries; Cattle; Cocaine; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propranolol | 1991 |
Prejunctional alpha 1-adrenoceptors modify release of [3H]noradrenaline in the guinea-pig vas deferens.
Topics: Animals; Clonidine; Cocaine; Desoxycorticosterone; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1990 |
Prazosin-sensitive component of the inotropic response to norepinephrine in rabbit heart.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1990 |
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cocaine; Dioxanes; Hypertension, Renovascular; Idazoxan; Kidney; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Potassium Chloride; Prazosin; Rabbits; Time Factors | 1990 |
Cocaine inhibits baroreflex control of blood pressure by actions at arterial baroreceptors.
Topics: Animals; Arteries; Blood Pressure; Carotid Sinus; Cocaine; Dose-Response Relationship, Drug; Nitroprusside; Osmolar Concentration; Prazosin; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex | 1990 |
Sympathetic reactivity of cerebral arteries in developing fetal lamb and adult sheep.
Topics: Aging; Animals; Animals, Newborn; Arterioles; Cerebral Arteries; Cocaine; Electric Stimulation; Fetus; Norepinephrine; Pia Mater; Prazosin; Sheep; Sympathetic Nervous System | 1990 |
Effect of monoamine uptake inhibitors on norepinephrine-stimulated phosphatidylinositol hydrolysis in rat cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Desipramine; Fluoxetine; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Receptors, Adrenergic, alpha | 1989 |
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
Topics: Animals; Basilar Artery; Cocaine; Dogs; In Vitro Techniques; Indomethacin; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Spiperone; Vasoconstriction | 1989 |
Presynaptic alpha 2-adrenoceptor modulation of 5-hydroxytryptamine and noradrenaline release from vascular adrenergic nerves.
Topics: Animals; Azepines; Clonidine; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Splanchnic Circulation; Sympathetic Nervous System; Synapses | 1989 |
Do both adrenaline and noradrenaline stimulate cardiac alpha-adrenoceptors to induce positive inotropy of rat atria?
Topics: Animals; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Haloperidol; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Timolol | 1989 |
Comparison between sympathetic adrenergic and purinergic transmission in the dog mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Cocaine; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1989 |
A pharmacological analysis of the discriminative stimulus properties of d-amphetamine in rhesus monkeys.
Topics: Animals; Apomorphine; Benzazepines; Cocaine; Dextroamphetamine; Discrimination Learning; Macaca mulatta; Male; Phentolamine; Pimozide; Prazosin; Receptors, Dopamine | 1989 |
Differential actions of cocaine and amphetamine on dorsal raphe neurons in vitro.
Topics: Amphetamine; Animals; Cocaine; In Vitro Techniques; Membrane Potentials; Neurons; Prazosin; Raphe Nuclei; Rats; Serotonin; Spiperone | 1989 |
Effect of pregnancy and sex steroids on alpha 1-adrenoceptor mechanisms in the guinea-pig uterine vascular bed.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Guinea Pigs; Isoproterenol; Norepinephrine; Normetanephrine; Potassium; Prazosin; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, alpha; Uterine Contraction; Uterus; Yohimbine | 1988 |
Pharmacological characterization of postsynaptic alpha-adrenoceptor subtypes in five different dog arteries in-vitro.
Topics: Animals; Antihypertensive Agents; Arteries; Brimonidine Tartrate; Cocaine; Dogs; In Vitro Techniques; Muscle, Smooth, Vascular; Phenylephrine; Prazosin; Propiophenones; Propranolol; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Yohimbine | 1985 |
Influence of extracellular calcium and nifedipine on alpha 1- and alpha 2-adrenoceptor-mediated contractile responses in isolated rat and cat cerebral and mesenteric arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cats; Cerebral Arteries; Cocaine; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Sodium; Yohimbine | 1985 |
Cocaine potentiates the responses to methacholine and noradrenaline in the rat vas deferens.
Topics: Animals; Cocaine; Drug Synergism; In Vitro Techniques; Male; Methacholine Compounds; Muscle, Smooth; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vas Deferens | 1985 |
Inhibition of the cholinergic neurotransmission in human airways via prejunctional alpha-2-adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adult; Aged; Bronchi; Cholinergic Fibers; Cocaine; Electric Stimulation; Humans; In Vitro Techniques; Lung; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Propranolol; Synaptic Transmission; Yohimbine | 1985 |
Effects of blockade of alpha 1- and alpha 2-adrenoceptors on vasoconstrictor responses to single and twin pulse stimulation in rat tail artery.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Cocaine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred Strains; Regional Blood Flow; Tail; Vasoconstriction | 1986 |
Prazosin-induced alterations in renal alpha-adrenergic receptor function.
Topics: Adrenergic beta-Agonists; Animals; Cocaine; Electric Stimulation; Hypotension; In Vitro Techniques; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Tachycardia; Vascular Resistance; Vasoconstriction; Yohimbine | 1987 |
Membrane properties and adrenergic responses in locus coeruleus neurons of young rats.
Topics: Adrenergic alpha-Agonists; Animals; Cocaine; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Norepinephrine; Phenylephrine; Prazosin; Rats | 1987 |
Release of [3H]-noradrenaline from the sympathetic nerves to bovine mesenteric lymphatic vessels and its modification by alpha-agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cocaine; Electric Stimulation; Feedback; Lymphatic System; Mesentery; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Xylazine; Yohimbine | 1988 |
Tonic and rhythmic contractions induced by dopamine and related amines in rat vasa deferentia are pharmacologically separable.
Topics: Amines; Animals; Calcium; Carbachol; Cocaine; Dopamine; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Octopamine; Prazosin; Pyrogallol; Rats; Rats, Inbred Strains; Temperature; Tyramine; Vas Deferens | 1988 |
Permissive role of spinal alpha 1-adrenoceptors in sudomotor efferents.
Topics: Animals; Catecholamines; Cats; Cocaine; Electric Stimulation; Female; Galvanic Skin Response; Ganglia, Spinal; Hypothalamus; Male; Neurons, Efferent; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Spinal Cord; Yohimbine | 1985 |
Alpha-adrenoceptor responsiveness in the aged rat.
Topics: Aging; Anesthesia; Animals; Blood Pressure; Cocaine; Decerebrate State; Ethanolamines; Heart Rate; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Xylazine | 1986 |
Antagonism of the behavioral effects of cocaine and d-amphetamine by prazosin.
Topics: Animals; Behavior, Animal; Bupropion; Cocaine; Columbidae; Dextroamphetamine; Male; Prazosin; Propiophenones; Saimiri | 1986 |
Evaluation of the role of norepinephrine in the reinforcing effects of psychomotor stimulants in rhesus monkeys.
Topics: Animals; Cocaine; Female; Fluoxetine; Macaca mulatta; Male; Norepinephrine; Prazosin; Psychomotor Performance; Reinforcement, Psychology; Self Administration | 1987 |
Endothelium inhibits responses of rabbit carotid artery to adrenergic nerve stimulation.
Topics: Animals; Biological Assay; Biological Products; Carotid Arteries; Cocaine; Electric Stimulation; Electrophysiology; Endothelium, Vascular; Hydrocortisone; Male; Methylene Blue; Nitric Oxide; Norepinephrine; Pargyline; Prazosin; Rabbits; Sympathetic Nervous System; Vasoconstriction | 1987 |
Prazosin: effect on psychomotor-stimulant cues and locomotor activity in mice.
Topics: Amphetamine; Animals; Cocaine; Cues; Discrimination, Psychological; Fluoxetine; Male; Mice; Mice, Inbred ICR; Motor Activity; Pimozide; Prazosin; Propranolol; Stereotyped Behavior | 1985 |
Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression.
Topics: Amphetamine; Anesthetics, Local; Animals; Biogenic Amines; Cocaine; Drug Interactions; Haloperidol; Kindling, Neurologic; Lidocaine; Male; Metergoline; Prazosin; Propranolol; Rats; Seizures; Yohimbine | 1985 |
Alpha-adrenoceptors, 5-hydroxytryptamine receptors and the action of dihydroergotamine in human venous preparations obtained during saphenectomy procedures for varicose veins.
Topics: Cocaine; Dihydroergotamine; Humans; In Vitro Techniques; Norepinephrine; Pizotyline; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Saphenous Vein; Vasoconstriction; Yohimbine | 1984 |
Pre- and postsynaptic alpha-adrenoceptor antagonism by neuroleptics in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Blood Pressure; Clonidine; Cocaine; Heart Rate; Phentolamine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1981 |
Dopamine decreases mesenteric blood flow in the anaesthetised dog through the stimulation of postsynaptic alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Cocaine; Dogs; Dopamine; Prazosin; Splanchnic Circulation; Tyramine; Yohimbine | 1982 |
Heterogeneity of the interaction between alpha 1- and alpha 2-adrenoceptor agonists with their respective receptors in the vascular system of the pithed rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Cocaine; Dopamine; Electric Stimulation; Emetics; Ethanolamines; Hemodynamics; Male; Naphthols; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetrahydronaphthalenes; Yohimbine | 1984 |
Postjunctional alpha 1-adrenoceptors: preferential innervation of alpha 1-adrenoceptors and the role of neuronal uptake.
Topics: Animals; Blood Pressure; Cats; Cocaine; Muscle, Smooth, Vascular; Neurons; Phenylephrine; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Regional Blood Flow; Spleen; Time Factors | 1982 |
Pre- and postsynaptic adrenergic activation by norepinephrine reuptake inhibitors in the field-stimulated rat vas deferens.
Topics: Amitriptyline; Animals; Chlorpromazine; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Protriptyline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1981 |
Alpha-1 adrenoceptors mediate secretory responses to norepinephrine in innervated and denervated rat submaxillary glands.
Topics: Animals; Clonidine; Cocaine; Denervation; Female; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Submandibular Gland | 1984 |
Nonadrenergic nature of prazosin-resistant, sympathetic contraction in the dog mesenteric artery.
Topics: Animals; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hydroxydopamines; In Vitro Techniques; Male; Mesenteric Arteries; Nicotine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Tetrodotoxin; Tyramine; Vasoconstriction | 1984 |
Effects of semirigid methoxamine analogs on vascular smooth muscle: studies of methoxy-2-aminotetralin and 2-aminoindane derivatives.
Topics: Animals; Cocaine; Dogs; In Vitro Techniques; Indans; Indenes; Methoxamine; Methysergide; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Prazosin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1982 |
Effect of BL-5111-A, prazosin and phentolamine on responses of canine cutaneous veins to adrenergic activation.
Topics: Animals; Cocaine; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Prazosin; Propranolol; Quinazolines; Saphenous Vein; Sympathomimetics | 1980 |
Evidence for a functional alpha 1A- (alpha 1C-) adrenoceptor mediating contraction of the rat epididymal vas deferens and an alpha 1B-adrenoceptor mediating contraction of the rat spleen.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Cocaine; Epididymis; Estradiol; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Vasoconstrictor Agents | 1995 |
Cocaine promotes an apparent direct vasoconstrictor effect of neuropeptide Y in the rat tail artery.
Topics: Age Factors; Animals; Cocaine; Drug Synergism; Male; Neuropeptide Y; Norepinephrine; Prazosin; Rats; Rats, Inbred F344; Tail; Vasoconstriction | 1995 |
Cocaine and benzoylecgonine constrict cerebral arteries by different mechanisms.
Topics: Animals; Calcium; Cats; Cerebral Arteries; Cocaine; Female; Male; Norepinephrine; Oxidopamine; Prazosin; Ryanodine; Sympathectomy, Chemical; Vasoconstriction; Vasomotor System; Verapamil; Yohimbine | 1995 |
The effect of adrenergic receptor antagonists on cocaine-induced ventricular fibrillation: alpha but not beta adrenergic receptor antagonists prevent malignant arrhythmias independent of heart rate.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Cocaine; Dogs; Heart Rate; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Ventricular Fibrillation | 1994 |
Cardiogenic shock induced by cocaine in swine with normal coronary arteries.
Topics: Animals; Blood Pressure; Cardiac Output; Cocaine; Coronary Circulation; Coronary Vessels; Female; Male; Myocardial Ischemia; Prazosin; Regional Blood Flow; Shock, Cardiogenic; Stroke Volume; Swine | 1994 |
Causes of differential cardiovascular sensitivity to cocaine. I: Studies in conscious rats.
Topics: Adrenal Medulla; Amphetamine; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Central Nervous System; Cocaine; Dose-Response Relationship, Drug; Eicosanoids; Heparin; Male; Pentolinium Tartrate; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta | 1994 |
Neural modulation of bovine mesenteric lymph node contraction.
Topics: Adenosine Triphosphate; Animals; Atropine; Cattle; Cocaine; Electric Stimulation; Evoked Potentials; Isometric Contraction; Lymph Nodes; Mesentery; Neurons; Phentolamine; Prazosin; Propranolol; Tetrodotoxin; Yohimbine | 1993 |
Acute cocaine toxicity: the effect of agents in non-seizure-induced death.
Topics: Animals; Anticonvulsants; Cocaine; Diazepam; Electrodes, Implanted; Electroencephalography; Male; Nifedipine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Respiratory Tract Diseases; Seizures | 1993 |
Cocaine acutely increases rat myometrial contractile activity by mechanisms other than potentiation of adrenergic pathways.
Topics: Animals; Catecholamines; Cocaine; Female; In Vitro Techniques; Myometrium; Prazosin; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Reserpine; Uterine Contraction; Yohimbine | 1993 |
Coronary vascular effects of cocaine in rats.
Topics: Animals; Cocaine; Coronary Vessels; Ergonovine; Hemodynamics; Male; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Effect of testosterone on the response of young rat vas deferens to norepinephrine.
Topics: Animals; Barium; Barium Compounds; Carbachol; Chlorides; Cocaine; Estradiol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Wistar; Testosterone; Vas Deferens | 1993 |
Power spectral analysis of electroencephalographic desynchronization induced by cocaine in rats: correlation with evaluation of noradrenergic neurotransmission at the medial prefrontal cortex.
Topics: Adrenergic Agents; Animals; Benzylamines; Cocaine; Electroencephalography; Extracellular Space; Male; Microinjections; Norepinephrine; Osmolar Concentration; Prazosin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Time Factors; Yohimbine | 1995 |
Prazosin-induced blockade of extraneuronal uptake facilitates dopaminergic modulation of muscle twitches in rat vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Estradiol; In Vitro Techniques; Male; Muscle Contraction; Prazosin; Rats; Rats, Wistar; Synaptic Transmission; Vas Deferens | 1995 |
Alpha 1-adrenergic receptor antagonist blocks acute cocaine action on the compound action potential of the auditory nerve in the chinchilla.
Topics: Adrenergic alpha-Antagonists; Animals; Chinchilla; Cocaine; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Auditory; Prazosin; Signal Processing, Computer-Assisted; Vestibulocochlear Nerve | 1995 |
Cardiorespiratory effects of cocaine and procaine at the ventral brainstem.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cats; Cocaine; Female; Hemodynamics; Injections, Intraventricular; Male; Medulla Oblongata; Narcotics; Prazosin; Procaine; Propranolol; Respiration | 1996 |
Evaluation of the cocaine-like discriminative stimulus effects and reinforcing effects of modafinil.
Topics: Adrenergic Agents; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ephedrine; Macaca mulatta; Male; Modafinil; Narcotics; Prazosin; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 1996 |
Blockade of alpha-2 adrenergic receptors in the rostral ventrolateral medulla attenuates the sympathoinhibitory response to cocaine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blood Pressure; Cocaine; Idazoxan; Male; Medulla Oblongata; Microinjections; Piperoxan; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sympatholytics | 1996 |
Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers.
Topics: Animals; Cocaine; Desipramine; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Tegmental Area | 1998 |
The adrenergic, cholinergic and NANC nerve-mediated contractions of the female rabbit bladder neck and proximal, medial and distal urethra.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Autonomic Nervous System; Cocaine; Electric Stimulation; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Parasympathetic Nervous System; Prazosin; Rabbits; Sympathetic Nervous System; Urethra; Urinary Bladder; Vasoconstrictor Agents; Yohimbine | 1998 |
Cocaine augments contractility of the pregnant human uterus by both adrenergic and nonadrenergic mechanisms.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Cocaine; Female; Humans; In Vitro Techniques; Methoxamine; Myometrium; Prazosin; Pregnancy; Receptors, Adrenergic, alpha; Sensitivity and Specificity; Uterine Contraction | 1998 |
Persistent release of noradrenaline caused by anticancer drug 4'-epidoxorubicin in rat tail artery in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Antibiotics, Antineoplastic; Arteries; Calcium; Cocaine; Culture Media; Electric Stimulation; Epirubicin; In Vitro Techniques; Male; Muscle Tonus; Norepinephrine; Prazosin; Rats; Rats, Wistar; Tail; Tetrodotoxin; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Pharmacological characterization of the discriminative stimulus properties of the phencyclidine analog, N-[1-(2-benzo(b)thiophenyl)-cyclohexyl]piperidine.
Topics: Animals; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Male; Norepinephrine; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 1999 |
Cocaine and exercise: alpha-1 receptor blockade does not alter muscle glycogenolysis or blood lactacidosis.
Topics: Acidosis, Lactic; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cocaine; Glycogen; Lactic Acid; Male; Muscle, Skeletal; Physical Conditioning, Animal; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Time Factors | 2000 |
Influence of castration on the response of the rat vas deferens to fluoxetine.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Castration; Cocaine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Male; Muscle Contraction; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Prazosin; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Testosterone; Vas Deferens | 2000 |
On the role of serotonin2A/2C receptors in the sensitization to cocaine.
Topics: Animals; Cocaine; Ketanserin; Male; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin | 2001 |
Critical role of alpha1-adrenergic receptors in acute and sensitized locomotor effects of D-amphetamine, cocaine, and GBR 12783: influence of preexposure conditions and pharmacological characteristics.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Habituation, Psychophysiologic; Hyperkinesis; Male; Neurons; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sodium Chloride; Synaptic Transmission | 2002 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
The effect of guanethidine and local anesthetics on the electrically stimulated mouse vas deferens.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cocaine; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Prazosin; Prilocaine; Procaine; Tetrodotoxin; Vas Deferens | 2002 |
Cocaine-induced hypophagia and hyperlocomotion in rats are attenuated by prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drinking; Eating; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley | 2002 |
Investigation of postjunctional alpha1- and alpha2-adrenoceptor subtypes in vas deferens from wild-type and alpha(2A/D)-adrenoceptor knockout mice.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Cocaine; Electric Stimulation; Imidazoles; Indoles; Isoindoles; Isometric Contraction; Male; Mice; Mice, Knockout; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic; Suramin; Thymine; Vas Deferens; Yohimbine | 2003 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Norepinephrine; Prazosin; Propranolol; Psychomotor Agitation; Rats; Rats, Wistar | 2003 |
Alpha1-adrenoceptor subtypes involved in vasoconstrictor responses to exogenous and neurally released noradrenaline in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; In Vitro Techniques; Male; Muscle, Skeletal; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors.
Topics: Animals; Carrier Proteins; Citalopram; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Heroin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Saimiri; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiophenes; Vesicular Biogenic Amine Transport Proteins | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
5-HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Administration Schedule; Drug Interactions; Fluorobenzenes; Male; Mice; Mice, Knockout; Microdialysis; Motor Activity; Narcotics; Phenols; Prazosin; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Time Factors | 2004 |
Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Mapping; Clonidine; Cocaine; Cognition Disorders; Discrimination Learning; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Macaca mulatta; Male; Membrane Proteins; Memory; Nerve Tissue Proteins; Neuropsychological Tests; Prazosin; Prefrontal Cortex; Radioligand Assay; Receptors, Catecholamine; Statistics as Topic; Tritium | 2005 |
Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Prazosin; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Reward | 2005 |
Role of alpha1-adrenoreceptors in cocaine-induced NADPH oxidase expression and cardiac dysfunction.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cardiomegaly; Cardiomyopathies; Cocaine; Male; Myocardium; NADPH Oxidases; Phenylephrine; Prazosin; Random Allocation; Rats; Rats, Wistar; Vasoconstrictor Agents; Ventricular Dysfunction, Left | 2005 |
Saw palmetto is an indirectly acting sympathomimetic in the rat-isolated prostate gland.
Topics: Amphetamine; Animals; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Male; Nifedipine; Phentolamine; Plant Extracts; Prazosin; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Serenoa; Sympathomimetics; Tyramine; Urinary Bladder; Vas Deferens | 2006 |
Previous exposure to cocaine enhances cocaine self-administration in an alpha 1-adrenergic receptor dependent manner.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Reinforcement Schedule; Self Administration | 2007 |
Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cocaine; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Yohimbine | 2006 |
AMPA and NMDA receptors in P2 fractions of cocaine and cocaine-prazosin-treated rats.
Topics: Animals; Cocaine; Drug Interactions; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 2006 |
Beneficial effects of prazosin for visual hallucinations associated with chronic cocaine abuse.
Topics: Adrenergic alpha-Antagonists; Chronic Disease; Cocaine-Related Disorders; Crack Cocaine; Hallucinations; Humans; Male; Middle Aged; Prazosin; Secondary Prevention | 2006 |
Vasoconstriction of porcine left anterior descending coronary artery by ecstasy and cathinone is not an indirect sympathomimetic effect.
Topics: Alkaloids; Animals; Cocaine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Swine; Sympathomimetics; Vasoconstriction | 2007 |
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Extinction, Psychological; Fluoxetine; Flupenthixol; Grooming; Hydrocortisone; Injections, Intravenous; Norepinephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-2; Saimiri; Saliva; Self Administration; Thiophenes | 2007 |
Differences in sympathetic neuroeffector transmission to rat mesenteric arteries and veins as probed by in vitro continuous amperometry and video imaging.
Topics: Animals; Cocaine; Electrophysiology; Glyoxylates; Mesenteric Arteries; Mesenteric Veins; Oxidation-Reduction; Prazosin; Pyridoxal Phosphate; Rats; Sympathetic Nervous System; Vasoconstriction; Video Recording; Yohimbine | 2007 |
Noradrenergic antagonism enhances the conditioned aversive effects of cocaine.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Taste | 2008 |
Lobeline attenuates progressive ratio breakpoint scores for intracranial self-stimulation in rats.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lobeline; Male; Medial Forebrain Bundle; Nicotinic Agonists; Prazosin; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration | 2008 |
Post-retrieval disruption of a cocaine conditioned place preference by systemic and intrabasolateral amygdala beta2- and alpha1-adrenergic antagonists.
Topics: Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug Administration Routes; Mental Recall; Microinjections; Oncogene Proteins v-fos; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley | 2009 |
A role for alpha-adrenergic receptors in extinction of conditioned fear and cocaine conditioned place preference.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Antagonists; Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Fear; Male; Mice; Mice, Inbred C57BL; Prazosin; Receptors, Adrenergic, alpha-1 | 2010 |
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Guanfacine; Imidazoles; Imidazoline Receptors; Isoquinolines; Male; Motor Activity; Naphthyridines; Prazosin; Propranolol; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2011 |
Cocaine self-administration is not dependent upon mesocortical α1 noradrenergic signaling.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine; Dopamine Antagonists; Male; Norepinephrine; Prazosin; Prefrontal Cortex; Rats; Reinforcement, Psychology; Reward; Self Administration; Ventral Tegmental Area | 2012 |
Prazosin differentially affects extinction of cocaine conditioned place preference on the basis of dose and initial preference.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Prazosin; Rats; Rats, Sprague-Dawley | 2012 |
Prazosin has low potency at α1A-adrenoceptors and high potency at α1D -adrenoceptors in rat vas deferens.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Piperazines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Thymine; Vas Deferens | 2013 |
Effects of desipramine on prazosin potency at α1A- and α1D-adrenoceptors in rat vas deferens: implications for the α1L-adrenoceptor subclassification.
Topics: Animals; Cocaine; Desipramine; Male; Muscle Contraction; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens | 2014 |
Memory of a drug lapse: Role of noradrenaline.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Animals; Basolateral Nuclear Complex; Clonidine; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Heroin; Locus Coeruleus; Male; Memory; Narcotics; Norepinephrine; Prazosin; Propranolol; Rats, Sprague-Dawley; Spatial Behavior; Substance-Related Disorders | 2015 |
Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Extinction, Psychological; Food; Male; Norepinephrine; Nucleus Accumbens; Prazosin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Reinforcement Schedule; Self Administration; Ventral Tegmental Area | 2017 |
Noradrenergic signaling in the VTA modulates cocaine craving.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Craving; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Idazoxan; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area | 2018 |
Synergistic interactions between mirtazapine and prazosin prevent the induction and expression of behavioral sensitization to cocaine in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Locomotion; Male; Mianserin; Mirtazapine; Prazosin; Rats; Rats, Wistar | 2017 |
A single dose of cocaine potentiates glutamatergic synaptic transmission onto locus coeruleus neurons.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Cocaine; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Injections, Intraperitoneal; Locus Coeruleus; Mice; Mice, Inbred C57BL; Microtomy; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tissue Culture Techniques | 2017 |
Drug-free and context-dependent locomotor hyperactivity in DBA/2 J mice previously treated with repeated cocaine: Relationship with behavioral sensitization and role of noradrenergic receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Association; Behavior, Animal; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Injections, Intraperitoneal; Locomotion; Male; Memory; Mice; Mice, Inbred DBA; Norepinephrine; Prazosin; Propranolol; Psychomotor Agitation; Receptors, Adrenergic | 2019 |