prazosin and atenolol
prazosin has been researched along with atenolol in 170 studies
Research
Studies (170)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (37.06) | 18.7374 |
| 1990's | 44 (25.88) | 18.2507 |
| 2000's | 37 (21.76) | 29.6817 |
| 2010's | 23 (13.53) | 24.3611 |
| 2020's | 3 (1.76) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Bavari, S; Besch, R; Duplantier, AJ; Jay, WB; Kota, KP; Kuehl, K; Lazić, M; Mudhasani, R; Panchal, RG; Pavić, A; Retterer, C; Sean, VA; Selaković, Ž; Šolaja, BA; Soloveva, V; Tran, JP; Vasiljević, B; Verbić, T | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Barritt, DW; Heaton, ST; Marshall, AJ; Pocock, J | 1 |
| Cleland, J; Coles, SJ; Humphreys, J; Ligueros, M; Unwin, R; Wilkins, MR | 1 |
| Guy, S; Humphreys, JE; Silke, B | 1 |
| Goldberg, SR; Schindler, CW; Tella, SR | 1 |
| Nurminen, ML; Paakkari, I | 1 |
| Malik, KU; Schwartz, DD | 1 |
| Daae, L; Talseth, T; Westlie, L | 2 |
| Kohno, M; Kurihara, N; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Boman, K; Jansson, JH; Johansson, B; Nilsson, TK | 1 |
| Lindgren, B | 1 |
| Balasubramaniam, S; Chang, S; Hickie, JB; Simons, LA | 1 |
| Elghozi, JL; Grichois, ML; Japundzic, N; Laude, D; Zitoun, P | 1 |
| Elkeles, RS; Feher, MD; Gelding, S; Henderson, AD; Poulter, C; Richmond, W; Sever, PS; Wadsworth, J | 1 |
| Bornmyr, S; De Pedis, G; Hulthén, UL; Lecerof, H; Lilja, B | 1 |
| Groppelli, A; Mancia, G; Omboni, S; Parati, G | 1 |
| Daae, LN; Talseth, T; Westlie, L | 1 |
| Engel, BT; Talan, MI | 2 |
| Rouffy, J | 1 |
| Elghozi, JL; Grichois, ML; Japundzic, N; Zitoun, P | 1 |
| Christensen, CC; Dathan, R; Dean, S; Searle, M; Westheim, A | 1 |
| Jansen, H | 1 |
| Amery, A; Fagard, R; Lijnen, P; Staessen, J | 2 |
| Baggen, MG; Birkenhäger, JC; Jansen, H; Lammers, R | 1 |
| Amery, A; Fagard, R; Lijnen, P; Lissens, W; Staessen, J | 1 |
| Bautovich, GJ; Fletcher, PJ; Gillin, AG; Horvath, JS; Hutton, BF; Tiller, DJ | 1 |
| Birkeland, S; Grong, K; Kvitting, P; Lekven, J; Westby, J | 1 |
| Duman, EL; Komsuoğlu, B; Komsuoğlu, SS; Ozgür, O | 1 |
| Costall, B; Naylor, RJ; Tan, CC | 1 |
| Cox, DA; Frick, MH; Himanen, P; Huttunen, M; Pitkäjärvi, T; Pörsti, P; Pöyhönen, L; Pyykönen, ML; Reinikainen, P; Salmela, P | 1 |
| Badskjaer, J; Faergeman, O; Jensen, H; Krusell, LR; Ott, P; Storm, TL | 1 |
| Black, H; Nash, DT; Reeves, RL; Schonfeld, G; Weidler, DJ | 1 |
| Yuwiler, A | 1 |
| Pandhi, P; Sharma, PL | 1 |
| Daae, L; Talseth, T; Vatle, S; Westlie, L | 1 |
| Guerrasio, E; Mazzola, C | 1 |
| Fioravanti, G; Giorgi, G; Legramante, A; Legramante, JM; Paies, G | 1 |
| Bredesen, J; Dale, O; Eriksen, K; Helgeland, A; Nafstad, I; Solberg, LA; Tollersrud, S | 1 |
| Jones, DL | 1 |
| Cullinane, EM; Nugent, AM; Sady, MA; Sady, SP; Thompson, PD | 1 |
| Krauss, RM; Superko, HR; Wood, PD | 1 |
| Brockway, BA; Johnson, J; Kwan, CM; Shepherd, AM; Taylor, WF | 1 |
| Itskovitz, HD; Khoury, S; Krug, K; Mollura, JL | 1 |
| Frick, MH; Halttunen, P; Himanen, P; Huttunen, M; Pitkäjärvi, T; Pörsti, P; Pöyhönen, L; Pyykönen, ML; Reinikainen, P; Salmela, P | 1 |
| Baez, MA; Garg, DC; Jallad, NS; Weidler, DJ | 1 |
| Himanen, P; Lehtonen, A; Marniemi, J; Niittymäki, K; Saraste, M | 1 |
| Cox, DA; Leader, JP; Milson, JA; Singleton, W | 1 |
| Faulkner, JK; Himanen, P; Karjalainen, U; Saraste, M | 1 |
| Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS | 1 |
| Holtzman, JL; Kaihlanen, PM; Lewin, AJ; Oberlin, JA; Rider, JA; Spindler, JS | 1 |
| Algarra Vidal, FJ; Bordes Siscar, P; Estruch Catala, G; Ferrer Reig, J; Gimeno Gascón, JV; Hernandez Martinez, M; Olague de Ros, J; Serra Flores, J | 1 |
| Johnson, J; Kwan, CM; Shepherd, AM; Taylor, WF | 1 |
| Jaillard, J; Rouffy, J | 3 |
| Aberg, H; Lithell, H; Selinus, I | 1 |
| Lowenstein, J; Neusy, AJ | 1 |
| Parnell, L; Ramsay, LE; Waller, PC | 1 |
| Green, KA; Lange Andersen, K; Ottmann, W; Piatkowski, W | 1 |
| Donker, AJ; May, JF; Schuurman, FH; ten Berge, BS; van der Veur, E; Wesseling, H | 1 |
| Ikäheimo, M; Jounela, AJ; Lilja, M; Mattila, MJ | 1 |
| Hengeveld, WL; Schouten, JA; Westerman, RF | 1 |
| Athias, P; Ettaiche, M; Klepping, J; Variot, N | 1 |
| Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ | 1 |
| Lindell, SE; Ohlsson, O | 1 |
| Cocco, F; Dessì Fulgheri, P; Dettori, S; Fiori, C; Glorioso, N; Madeddu, P; Rappelli, A; Sanna, G | 1 |
| Higginson, LM; Opie, LH; Thandroyen, FT; Worthington, MG | 1 |
| Brown, JE; Kitchell, BB; Kuhn, C; McLeod, AA; Sedor, FA; Shand, DG; Williams, RS | 1 |
| Hülsmann, WC; Jansen, H; Schoonderwoerd, K | 1 |
| Birkenhäger, WH; de Leeuw, PW; van Soest, GA | 1 |
| Hilakivi, I | 1 |
| Asano, Y; Imai, M; Kusano, E; Nakamura, R | 1 |
| DiBona, GF; Holdaas, H; Osborn, JL; Thames, MD | 1 |
| Carter, DC; Farah, DA; Lorimer, AR; Mills, PR; Rae, AP; Russell, RI | 1 |
| Latham, L; Lorimer, AR; McAreavey, D; McLaren, AD; Ramsey, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ | 1 |
| Freslon, JL; Giudicelli, JF; Richer, C | 1 |
| Antonini, G; Franconi, F; Giotti, A; Ledda, F; Mantelli, L; Stendardi, I | 1 |
| Brown, JE; Kitchell, BB; Kuhn, DC; McLeod, AA; Sedor, FA; Shand, DG; Williams, RS | 1 |
| Ellingsen, O; Kjekshus, J | 1 |
| Hintze, TH; Vatner, SF | 1 |
| Aärynen, M; Hämeenaho, P; Mäkelä, M; Mattila, MJ | 1 |
| Labeeuw, M; Trotta, P; Zech, PY | 1 |
| Jones, JV; Steiner, JM | 1 |
| Kigoshi, S; Muramatsu, I; Oda, Y; Takita, M | 1 |
| Shi, CZ; Zhuang, LZ | 1 |
| Formolo, JM; Penney, DG | 1 |
| Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ | 1 |
| Watson, A | 1 |
| Gertner, SB; Hey, JA; McLeod, RL | 1 |
| Bangaru, RA; Goyal, RK; Lakkad, NB; Rao, MV | 1 |
| Burrello, N; Calogero, AE; D'Agata, R; Ossino, AM; Weber, RF | 1 |
| Inada, Y; Kanagawa, R; Nishikawa, K; Ojima, M; Sanada, T; Wada, T | 1 |
| Dunbar, JC; O'Leary, DS; Wang, G; Wright-Richey, J | 1 |
| Feldman, S; Weidenfeld, J | 1 |
| Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Aubineau, P; Callebert, J; Launay, JM; Reynier-Rebuffel, AM; Seylaz, J | 1 |
| Baudrie, V; Blanc, J; Elghozi, JL; Tulen, JH | 1 |
| Elghozi, JL; Laude, D; Ponchon, P; Safa-Tisseront, V | 2 |
| Chau, NP; Dabiré, H; Jarnet, J; Mestivier, D; Safar, ME | 1 |
| Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ | 1 |
| Ferry, B; McGaugh, JL; Roozendaal, B | 1 |
| Benck, U; Clorius, JH; Ritz, E; Zuna, I | 1 |
| Hashimoto, K; Ozaki, Y; Sugiyama, A; Yatomi, Y | 1 |
| Badilini, F; Bril, A; Carré, F; Gout, B; Maison-Blanche, P; Pladys, P | 1 |
| Elghozi, JL; Girard, A; Holand, S; Laude, D | 1 |
| Katzer, C; Piper, HM; Schlüter, KD | 1 |
| Dahanukar, SA; Joglekar, SJ; Kamat, SK; Nanivadekar, AS; Patki, KC; Rege, NN; Thatte, UM; Yeolekar, ME | 1 |
| Ghosh, B; Khanam, J; Kulkarni, RV; Reddy, LH | 1 |
| Jaguste, V; Joglekar, SJ; Nanivadekar, AS | 1 |
| Ghosh, B; Reddy, LH | 2 |
| Enzminger, H; Lemmer, B; Witte, K | 1 |
| Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Hirata, Y; Imai, T; Imai, Y; Kayaba, Y; Kurihara, H; Kurihara, Y; Kuwaki, T; Morita, H; Nagai, R; Nishimatsu, H; Oh-hashi, Y; Shindo, T; Suematsu, Y; Wang, Y; Yazaki, Y | 1 |
| Brown, RA; Chen, AF; Ilg, KJ; Ren, J | 1 |
| Akai, M; Hong, B; Ju, K; Kumada, M; Kuwaki, T; Ueno, S | 1 |
| Bur, A; Derhaschnig, U; Herkner, H; Hirschl, MM; Quehenberger, P; Woisetschläger, C | 1 |
| Leenen, FH; Ruzicka, M | 1 |
| Adigun, AQ; Ajayi, AA; Asiyanbola, B; Sofowora, GG | 2 |
| Akimoto, Y; Horinouchi, T; Koike, K; Tanaka, Y | 1 |
| Anesini, C; Borda, E; Coussio, J; Ferraro, G; Turner, S | 1 |
| Gokee, A; Rocchini, AP; Yang, JQ | 1 |
| Brands, MW; Lee, DL; Webb, RC | 1 |
| Fukuda, Y; Kuwaki, T; Sakurai, T; Zhang, W | 1 |
| Baudrie, V; Elghozi, JL; Laude, D | 2 |
| Abzalov, NI; Abzalov, RR; Ziyatdinova, AI | 1 |
| Andrag, E; Clements-Jewery, H; Curtis, MJ; Hearse, DJ | 1 |
| Chopra, M; Sharma, AC | 1 |
| Froehlich, D; Graf, B; Gruber, M; Lunz, D; Trabold, B | 1 |
| Friedman, GD; Habel, LA; Udaltsova, N | 1 |
| Castania, JA; Durand, Mde T; Fazan, R; Salgado, HC; Salgado, MC | 1 |
| Hsiao, AF; Longhurst, JC; Tjen-A-Looi, SC | 1 |
| Chen, CY; Chuan, TY; Kuo, TB; Lai, CT; Tsai, SC; Wu, WY; Yang, CC | 1 |
| Chen, CY; Kuo, TB; Lai, CT; Lee, GS; Yang, CC | 1 |
| Dietrich, D; Green, I; Mugabo, P; Philander, A; Raji, I | 1 |
| Hamaguchi, S; Hasegawa, N; Ichige, S; Irie, M; Mochizuki, S; Namekata, I; Shimobayashi, M; Tanaka, H; Tanaka, Y; Tsuneoka, Y | 1 |
| Aalkjaer, C; Matchkov, VV; Mazur, A; Overgaard, CB; Postnov, DD; Søndergaard, AM | 1 |
| Asada, Y; Jiang, D; Kato, J; Kawagoe, Y; Kitamura, K | 1 |
Reviews
2 review(s) available for prazosin and atenolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Combination therapy as first-line treatment of arterial hypertension.
Topics: Antihypertensive Agents; Atenolol; Captopril; Diltiazem; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Prazosin; Treatment Outcome | 2002 |
Trials
63 trial(s) available for prazosin and atenolol
| Article | Year |
|---|---|
Evaluation of beta blockade bendrofluazide, and prazosin in severe hypertension.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Prazosin; Propranolol; Quinazolines | 1977 |
A comparison of the effects of the selective peripheral alpha 1-blocker terazosin with the selective beta 1-blocker atenolol on blood pressure, exercise performance and the lipid profile in mild-to-moderate essential hypertension.
Topics: Adult; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Prazosin; Randomized Controlled Trials as Topic | 1992 |
Comparison of antihypertensive and lipid actions of terazosin and atenolol in essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Hypolipidemic Agents; Lipids; Male; Middle Aged; Prazosin | 1992 |
Doxazosin and atenolol as monotherapy in mild and moderate hypertension: a randomized, parallel study with a three-year follow-up.
Topics: Antihypertensive Agents; Atenolol; Cholesterol; Coronary Disease; Double-Blind Method; Doxazosin; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Norway; Prazosin; Risk Factors; Time Factors | 1991 |
Acute effects of alpha- and beta-adrenoceptor blockade on plasma atrial natriuretic peptides during exercise in elderly patients with mild hypertension.
Topics: Aged; Atenolol; Atrial Natriuretic Factor; Carteolol; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Prazosin; Ventricular Function, Left | 1991 |
Effects of doxazosin and atenolol on the fibrinolytic system in patients with hypertension and elevated serum cholesterol.
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Body Weight; Double-Blind Method; Doxazosin; Female; Fibrinolysis; Heart Rate; Humans; Hypercholesterolemia; Hypertension; Male; Plasminogen Inactivators; Prazosin; Randomized Controlled Trials as Topic; Risk Factors; Tissue Plasminogen Activator | 1991 |
Alpha-blocker therapy; a possible advance in the treatment of diabetic hypertension--results of a cross-over study of doxazosin and atenolol monotherapy in hypertensive non-insulin dependent diabetic subjects.
Topics: Adrenergic alpha-Antagonists; Aged; Atenolol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Doxazosin; Female; Glucose; Humans; Hypertension; Lipoproteins; Male; Middle Aged; Prazosin | 1990 |
Acute effects of doxazosin and atenolol on smoking-induced peripheral vasoconstriction in hypertensive habitual smokers.
Topics: Adrenergic alpha-Antagonists; Adult; Atenolol; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Plethysmography; Prazosin; Skin; Smoking; Thermography; Ultrasonography; Vascular Resistance; Vasoconstriction | 1990 |
Blood pressure and heart rate response to repeated smoking before and after beta-blockade and selective alpha 1 inhibition.
Topics: Adrenergic alpha-Antagonists; Adult; Atenolol; Blood Pressure; Doxazosin; Heart Rate; Humans; Hypertension; Prazosin; Single-Blind Method; Smoking | 1990 |
Long-term effects of doxazosin and atenolol on serum lipids and blood pressure in hypertensive smokers.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Atenolol; Double-Blind Method; Doxazosin; Female; Hemodynamics; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Retrospective Studies; Smoking | 1990 |
[Alpha-1 inhibition. Prevention of coronary risk factors].
Topics: Atenolol; Coronary Disease; Delayed-Action Preparations; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Risk Factors | 1990 |
Doxazosin in combination with atenolol in essential hypertension: a double-blind placebo-controlled multicentre trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Prazosin | 1990 |
A long-term study of atenolol and doxazosin in mild and moderate hypertension.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Cholesterol; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Risk Factors; Time Factors; Triglycerides | 1990 |
Antihypertensive effect of doxazosin and atenolol in short- and long-term double-blind comparison.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Doxazosin; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Regression Analysis | 1990 |
Short-term double-blind comparison of doxazosin and atenolol in patients with mild to moderate hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Random Allocation; Regression Analysis | 1988 |
Long-term double-blind comparison of doxazosin and atenolol in patients with mild to moderate hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Chemical Analysis; Blood Pressure; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Random Allocation; Time Factors | 1989 |
Comparison of doxazosin and atenolol in mild hypertension, and effects on exercise capacity, hemodynamics and left ventricular function.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Prazosin; Radionuclide Imaging | 1989 |
The effect of chronic antihypertensive therapy on the index of left ventricular mass in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Atenolol; Cardiac Volume; Clinical Trials as Topic; Echocardiography; Female; Follow-Up Studies; Heart Ventricles; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Male; Middle Aged; Prazosin; Random Allocation; Reserpine | 1989 |
Serum lipid changes in a one-year, multicenter, double-blind comparison of doxazosin and atenolol for mild to moderate essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Random Allocation; Time Factors | 1987 |
Multicenter, double-blind comparison of doxazosin and atenolol in patients with mild to moderate hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Lipoproteins; Male; Middle Aged; Prazosin | 1987 |
A double-blind parallel trial to assess the efficacy of doxazosin, atenolol and placebo in patients with mild to moderate systemic hypertension.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Heart Rate; Humans; Hypertension; Lipids; Placebos; Prazosin; Random Allocation | 1987 |
Comparative effects of beta-, alpha- and combined beta- plus alpha-adrenoceptor blocking agents in stress-induced increase in arterial blood pressure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cold Temperature; Double-Blind Method; Heart Rate; Humans; Isometric Contraction; Labetalol; Male; Prazosin; Propranolol; Random Allocation; Stress, Physiological | 1987 |
Comparison of the effects of doxazosin and atenolol on blood pressure and blood lipids: a one-year, double-blind study in 228 hypertensive patients.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Coronary Disease; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin | 1988 |
Doxazosin versus atenolol: a randomized comparison of calculated coronary heart disease risk reduction.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Coronary Disease; Doxazosin; Female; Heart Rate; Humans; Lipids; Male; Middle Aged; Prazosin; Random Allocation; Risk | 1988 |
A comparative study of doxazosin versus atenolol in mild-to-moderate hypertension.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Doxazosin; Electrocardiography; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin | 1988 |
Effect of atenolol or prazosin on maximal exercise performance in hypertensive joggers.
Topics: Adult; Aged; Atenolol; Blood Pressure; Cardiac Output; Exercise Test; Heart Rate; Humans; Hypertension; Jogging; Male; Middle Aged; Oxygen Consumption; Prazosin; Running; Vascular Resistance | 1989 |
Effect of alpha- and selective beta-blockade for hypertension control on plasma lipoproteins, apoproteins, lipoprotein subclasses, and postprandial lipemia.
Topics: Apoproteins; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Eating; Humans; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Prazosin; Triglycerides | 1989 |
Forearm and finger hemodynamics, blood pressure control, and lipid changes in diabetic hypertensive patients treated with atenolol and prazosin. A brief report.
Topics: Adult; Aged; Atenolol; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Female; Fingers; Forearm; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Regional Blood Flow; Vascular Resistance | 1989 |
The long-term antihypertensive effects of prazosin and atenolol.
Topics: Atenolol; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prazosin; Time Factors | 1989 |
A long-term double-blind comparison of doxazosin and atenolol in patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Kinetics; Lipids; Male; Middle Aged; Prazosin; Random Allocation | 1986 |
Antihypertensive effect of doxazosin in hypertensive patients: comparison with atenolol.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Random Allocation | 1986 |
Double-blind comparison of the effects of long-term treatment with doxazosin or atenolol on serum lipoproteins.
Topics: Adult; Aged; Antihypertensive Agents; Apolipoproteins; Atenolol; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Humans; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Prazosin; Random Allocation; Time Factors; Triglycerides | 1986 |
The antihypertensive effects of doxazosin: a clinical overview.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Metoprolol; Middle Aged; Nadolol; Prazosin; Propanolamines; Random Allocation; Risk; Triglycerides | 1986 |
The pharmacokinetics and pharmacodynamics of doxazosin compared with atenolol during long-term double-blind treatment.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hypertension; Kinetics; Male; Middle Aged; Prazosin; Random Allocation | 1987 |
Concomitant administration of terazosin and atenolol for the treatment of essential hypertension.
Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin | 1988 |
Exercise stress test in young hypertensive patients. Response to vasodilators (prazosin) vs. beta-blocker (atenolol) agents.
Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Hypertension; Male; Prazosin | 1988 |
Forearm and finger hemodynamics, blood pressure control, and lipid changes in patients with diabetic hypertension treated with atenolol and prazosin.
Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Female; Fingers; Forearm; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Prazosin; Random Allocation; Regional Blood Flow; Vascular Resistance | 1988 |
Effects of two antihypertensive agents on lipids, lipoproteins, and apoproteins A and B. Comparison of prazosin and atenolol.
Topics: Adult; Aged; Apolipoproteins A; Apolipoproteins B; Atenolol; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Lipid Metabolism; Lipoproteins; Lipoproteins, VLDL; Male; Middle Aged; Prazosin; Random Allocation; Time Factors; Triglycerides | 1986 |
Metabolic effects of a change in antihypertensive treatment.
Topics: Animals; Atenolol; Blood Glucose; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Female; Glucose; Humans; Hypertension; Insulin; Lipid Metabolism; Lipoproteins, HDL; Male; Middle Aged; Prazosin; Triglycerides | 1986 |
Effects of prazosin, atenolol, and thiazide diuretic on plasma lipids in patients with essential hypertension.
Topics: Atenolol; Benzothiadiazines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Lipid Metabolism; Lipids; Male; Prazosin; Random Allocation; Sodium Chloride Symporter Inhibitors; Time Factors; Triglycerides | 1986 |
Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Prazosin; Random Allocation | 1987 |
[Comparative study of the effects of prazosin and atenolol on plasma lipids of hypertensive patients].
Topics: Atenolol; Clinical Trials as Topic; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Quinazolines | 1985 |
Working ability and exercise tolerance during treatment of mild hypertension. II. A comparison between atenolol and prazosin medication.
Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Disability Evaluation; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Physical Endurance; Physical Exertion; Prazosin; Quinazolines; Random Allocation; Work Capacity Evaluation | 1985 |
A comparison of labetalol and prazosin combined with atenolol in non-responders to atenolol plus hydrochlorothiazide in uncomplicated hypertension.
Topics: Adult; Atenolol; Chlorothiazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Prazosin; Random Allocation; Time Factors | 1985 |
Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.
Topics: Adult; Atenolol; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Physical Exertion; Prazosin | 1985 |
Prazosin once or twice daily?
Topics: Adult; Aged; Amiloride; Atenolol; Blood Pressure; Chlorthalidone; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Propranolol; Quinazolines | 1985 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol | 1980 |
Hemodynamic and metabolic responses to exercise after adrenoceptor blockade in humans.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atenolol; Epinephrine; Fatty Acids, Nonesterified; Glycogen; Hemodynamics; Humans; Male; Norepinephrine; Physical Exertion; Prazosin; Propranolol | 1984 |
Comparison of three adrenoreceptor blocking agents in patients with cirrhosis and portal hypertension.
Topics: Atenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Portal Vein; Prazosin; Propranolol; Quinazolines | 1984 |
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Minoxidil; Prazosin | 1984 |
Hemodynamic and metabolic responses to exercise after alpha 1-, beta 1-, and nonselective beta-adrenoceptor blockade in man.
Topics: Adult; Atenolol; Blood Glucose; Catecholamines; Fatty Acids, Nonesterified; Hemodynamics; Humans; Lactates; Male; Physical Exertion; Prazosin; Propranolol; Quinazolines | 1984 |
[Prazosin in exercise-induced angina pectoris. An open study of work capacity after a single dose of prazosin, isosorbide dinitrate, atenolol and nifedipine].
Topics: Adult; Aged; Angina Pectoris; Atenolol; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Physical Exertion; Prazosin; Quinazolines | 1984 |
Prazosin enhances the antihypertensive effects of beta-blockers during isometric and dynamic exercise.
Topics: Adult; Atenolol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Prazosin; Propanolamines; Quinazolines; Sotalol | 1981 |
Double-blind cross-over comparison of hydralazine and prazosin in hypertensive subjects on a beta-adrenoceptor blocking agent (atenolol).
Topics: Atenolol; Double-Blind Method; Drug Therapy, Combination; Humans; Hydralazine; Hypertension; Prazosin; Propanolamines; Quinazolines | 1980 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin | 1993 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs | 1997 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States | 1999 |
Renal hemodynamic changes during smoking: effects of adrenoreceptor blockade.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Cohort Studies; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Kidney; Male; Norepinephrine; Prazosin; Renal Circulation; Renin; Smoking | 1999 |
Effect of prazosin GITS, atenolol, nifedipine SR, and enalapril on ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Delayed-Action Preparations; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Platelet Aggregation; Prazosin; Single-Blind Method | 1998 |
Prazosin GITS vs atenolol in patients with hypertension and normal lipid profile: a randomized, controlled multicenter study. Hyderabad Hypertension Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Delayed-Action Preparations; Female; Heart; Humans; Hypertension; Lipids; Male; Middle Aged; Prazosin; Time Factors; Treatment Outcome | 1998 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome | 2001 |
[Effects of terazosine and atenolol on serum lipids in essential hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Lipids; Male; Middle Aged; Prazosin; Prospective Studies; Triglycerides | 2002 |
Adjunctive sympathoplegic therapy to ACE inhibition in Blacks with congestive heart failure: a comparison of alpha-1 with beta-1 blockade on exercise tolerance and cardiac sympathovagal reflex activity.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Black People; Blood Pressure; Drug Therapy, Combination; Enalapril; Exercise Tolerance; Female; Heart Failure; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nigeria; Prazosin; Prospective Studies; Respiration; Single-Blind Method | 2003 |
Other Studies
105 other study(ies) available for prazosin and atenolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action.
Topics: Animals; Antiviral Agents; Chrysenes; Ebolavirus; Hemorrhagic Fever, Ebola; Lysosomes; Mice; Surface-Active Agents; Virus Internalization; Zebrafish | 2019 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
Adrenoceptor mechanisms in the cardiovascular effects of cocaine in conscious squirrel monkeys.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cocaine; Heart Rate; Labetalol; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saimiri; Yohimbine | 1992 |
Role of peripheral and central catecholaminergic and cholinergic mechanisms in the cardiovascular effects of thyrotropin-releasing hormone.
Topics: Animals; Atenolol; Atropine Derivatives; Blood Pressure; Brain; Butoxamine; Cerebral Ventricles; Fenclonine; Haloperidol; Heart Rate; Injections, Intraperitoneal; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Reserpine; Thyrotropin-Releasing Hormone; Vagotomy; Yohimbine | 1991 |
Mechanism of neurotransmitter release elicited by the preferential alpha 1-adrenergic receptor agonist phenylephrine in superfused superior cervical ganglion cells in culture.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atenolol; Cells, Cultured; Cocaine; Cyclic AMP; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Ethanolamines; Ganglia, Sympathetic; Kidney; Methoxamine; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Potassium Chloride; Prazosin; Propranolol; Rats; Tritium | 1991 |
The cost-benefit approach to pricing new medicines: doxazosin versus beta-blocker treatment in Sweden.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cost-Benefit Analysis; Doxazosin; Humans; Hypertension; Lipoproteins, HDL; Male; Middle Aged; Prazosin; Sweden | 1990 |
The effects of adrenergic blockade on lipoproteins using the rat as an experimental model.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Celiprolol; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Lipids; Lipoproteins; Male; Pindolol; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Triglycerides | 1990 |
Spectral analysis of blood pressure and heart rate in conscious rats: effects of autonomic blockers.
Topics: Animals; Atenolol; Atropine; Autonomic Nerve Block; Autonomic Nervous System; Blood Pressure; Fourier Analysis; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Prazosin; Rats; Rats, Inbred Strains; Spectrum Analysis | 1990 |
Autonomic blockade does not prevent learned heart rate attenuation during exercise.
Topics: Animals; Atenolol; Atropine Derivatives; Autonomic Nervous System; Blood Pressure; Conditioning, Operant; Dose-Response Relationship, Drug; Heart Rate; Macaca mulatta; Male; Oxygen; Parasympatholytics; Physical Conditioning, Animal; Prazosin; Vagus Nerve; Vascular Resistance | 1991 |
[Nervous mechanisms of spontaneous oscillations of systolic blood pressure and heart rate].
Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Biological Clocks; Blood Pressure; Heart Rate; Male; Prazosin; Rats; Rats, Inbred Strains; Spectrum Analysis; Systole | 1990 |
The mode of action of alpha 1-adrenoceptor blockers on blood lipids.
Topics: Animals; Atenolol; Cholesterol, Dietary; Cholesterol, HDL; Cricetinae; Doxazosin; Humans; Lipoprotein Lipase; Mesocricetus; Prazosin; Propranolol; Time Factors; Triglycerides | 1990 |
Effects of doxazosin on lipids, lipoprotein lipases, and cholesterol synthesis in the golden hamster.
Topics: Adrenergic alpha-Antagonists; Animals; Atenolol; Cholesterol; Cholesterol, Dietary; Cricetinae; Doxazosin; Insulin; Lipase; Lipoprotein Lipase; Liver; Male; Mesocricetus; Norepinephrine; Prazosin; Propranolol; Thyroid Hormones; Triglycerides | 1989 |
Does alpha 1-adrenergic blockade influence regional blood flow regulation in hearts with coronary artery occlusion?
Topics: Animals; Atenolol; Cats; Coronary Circulation; Coronary Disease; Doxazosin; Female; Male; Prazosin; Vasodilator Agents | 1989 |
Mechanism of action of apomorphine on rat gastric secretion.
Topics: Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Apomorphine; Atenolol; Drug Interactions; Gastric Acid; Gastric Mucosa; Male; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors; Yohimbine | 1985 |
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1987 |
The influence of atenolol and prazosin on serum lipids and atherosclerosis in minipigs fed a hyperlipidemic diet.
Topics: Animals; Arteriosclerosis; Atenolol; Body Weight; Cholesterol, Dietary; Diet; Female; gamma-Glutamyltransferase; Glutathione; Hyperlipidemias; Lipids; Liver; Male; Prazosin; Swine; Swine, Miniature; Vitamin E | 1988 |
Hypothalamic alpha-adrenergic blockade modifies drinking and blood pressure responses to central angiotensin II in conscious rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Atenolol; Blood Pressure; Cerebral Ventricles; Drinking Behavior; Hippocampus; Injections, Intraventricular; Male; Phentolamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Yohimbine | 1988 |
Effect of sympathetic blockade on diurnal variation of hemodynamic patterns.
Topics: Animals; Atenolol; Blood Pressure; Cardiac Output; Circadian Rhythm; Diastole; Drug Interactions; Heart Rate; Hemodynamics; Isoproterenol; Macaca mulatta; Male; Prazosin; Reference Values; Stroke Volume; Sympathetic Nervous System; Systole; Vascular Resistance | 1989 |
Ischemia- and reperfusion-induced arrhythmias in conscious rats--studies with prazosin and atenolol.
Topics: Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Male; Myocardial Reperfusion Injury; Myocardium; Prazosin; Rats; Rats, Inbred Strains; Tachycardia; Ventricular Fibrillation | 1988 |
Characterization of postjunctional adrenoceptor subtypes in isolated rat myocardial cells in culture.
Topics: Action Potentials; Albuterol; Animals; Atenolol; Cells, Cultured; Clonidine; Heart; Heart Rate; Isoproterenol; Methoxamine; Myocardium; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic | 1985 |
The effects of pindolol and prazosin on hand blood flow in patients with cold extremities and on treatment with beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cold Temperature; Female; Hand; Humans; Hypertension; Male; Middle Aged; Pindolol; Prazosin; Propanolamines; Quinazolines; Regional Blood Flow | 1981 |
[Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Chlorthalidone; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Metoprolol; Middle Aged; Prazosin; Renin; Sotalol; Spironolactone | 1981 |
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Atenolol; Coronary Circulation; Coronary Disease; Isoproterenol; Metoprolol; Perfusion; Phentolamine; Prazosin; Propranolol; Rats; Time Factors; Ventricular Fibrillation; Yohimbine | 1983 |
Regulation of liver lipase. II. Involvement of the alpha 1-receptor.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cholesterol, HDL; Ether; Lipase; Liver; Male; Metoprolol; Norepinephrine; Prazosin; Propranolol; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Aldosterone response to antihypertensive treatment.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Dipeptides; Enalapril; Ethanolamines; Humans; Hypertension; Middle Aged; Prazosin; Pyridazines; Renin; Renin-Angiotensin System; Vasodilator Agents; Verapamil | 1982 |
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages | 1983 |
Distribution of alpha-adrenergic receptors in the rabbit nephron.
Topics: Animals; Atenolol; Female; Isoproterenol; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Norepinephrine; Phenoxybenzamine; Prazosin; Quinazolines; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha; Tissue Distribution | 1984 |
Renal adrenoceptor mediation of antinatriuretic and renin secretion responses to low frequency renal nerve stimulation in the dog.
Topics: Animals; Atenolol; Dogs; Electric Stimulation; Female; Kidney; Male; Natriuresis; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Renin | 1983 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Relationship, Drug; Hydrochlorothiazide; Hypertension; Male; Nicardipine; Nifedipine; Prazosin; Rats; Rats, Inbred Strains; Time Factors; Vasodilator Agents | 1980 |
Reoxygenation dysrhythmias in the isolated guinea-pig heart: sensitivity to prazosin, atenolol and practolol.
Topics: Animals; Arrhythmias, Cardiac; Atenolol; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Oxygen; Perfusion; Practolol; Prazosin; Quinazolines | 1983 |
Comparative effects of prazosin and atenolol on plasma lipids in hypertensive patients.
Topics: Adult; Atenolol; Blood Pressure; Cholesterol; Female; Heart Rate; Humans; Hypertension; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Prazosin; Quinazolines; Triglycerides | 1984 |
Mechanism of constriction of large coronary arteries by beta-adrenergic receptor blockade.
Topics: Animals; Arteries; Atenolol; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Vascular Resistance; Vasoconstriction | 1983 |
[Treatment of severe resistant arterial hypertension with captopril. 58 patients, including 38 treated for more than 6 months (author's transl)].
Topics: Adult; Aged; Atenolol; Captopril; Diet, Sodium-Restricted; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Proline | 1981 |
Effects of propranolol and atenolol on immobilization stress-induced hypertension and down-regulation of central beta-adrenoceptors in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cerebral Cortex; Dihydroalprenolol; Down-Regulation; Drinking; Hypertension; Immobilization; Male; Prazosin; Propranolol; Rats; Rats, Wistar; Stress, Psychological; Weight Gain | 1995 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine | 1993 |
Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat.
Topics: Animals; Atenolol; Blood Pressure; Body Weight; Carbon Monoxide; Cardiomegaly; Heart Rate; Lung; Male; Organ Size; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1993 |
Don't get stung with the adrenergic blockers (beta or alpha)!
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anaphylaxis; Animals; Antihypertensive Agents; Atenolol; Bees; Contraindications; Drug Interactions; Epinephrine; Humans; Insect Bites and Stings; Male; Middle Aged; Prazosin | 1995 |
Hemodynamic profile of activation of histamine H3 receptors by R-alpha-methylhistamine in the guinea pig.
Topics: Animals; Atenolol; Guinea Pigs; Hemodynamics; Hexamethonium; Histamine Agonists; Male; Methylhistamines; Prazosin; Receptors, Histamine H3; Verapamil | 1996 |
Effect of chronic treatment with atenolol and prazosin in streptozotocin induced diabetic rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Diabetes Mellitus, Experimental; Female; Hemodynamics; Lipids; Prazosin; Rats; Rats, Wistar; Streptozocin | 1996 |
Interaction between prolactin and catecholamines on hypothalamic GnRH release in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Corticotropin-Releasing Hormone; Depression, Chemical; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Organ Culture Techniques; Phentolamine; Prazosin; Prolactin; Propanolamines; Propranolol; Rats; Rats, Sprague-Dawley; Yohimbine | 1996 |
Combined effects of the angiotensin II antagonist candesartan cilexetil (TCV-116) and other classes of antihypertensive drugs in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Hydrochlorothiazide; Male; Nitrobenzenes; Piperazines; Prazosin; Rats; Rats, Inbred SHR; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles | 1996 |
Mechanisms mediating insulin-induced hypotension in rats. A role for nitric oxide and autonomic mediators.
Topics: Animals; Antihypertensive Agents; Atenolol; Atropine; Autonomic Nervous System; Blood Glucose; Blood Pressure; Cohort Studies; Enzyme Inhibitors; Heart Rate; Hexamethonium; Hypoglycemic Agents; Hypotension; Insulin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prazosin; Rats; Rats, Wistar | 1996 |
Involvement of amygdalar alpha adrenoceptors in hypothalamo-pituitary-adrenocortical responses.
Topics: Adrenal Cortex; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Atenolol; Hypothalamo-Hypophyseal System; Immunohistochemistry; Injections; Male; Norepinephrine; Photic Stimulation; Pituitary-Adrenal System; Prazosin; Rats; Receptors, Adrenergic, alpha | 1996 |
NE inhibits cerebrovascular mast cell exocytosis induced by cholinergic and peptidergic agonists.
Topics: Adrenergic Antagonists; Animals; Atenolol; Carbachol; Cerebral Arteries; Cerebrovascular Circulation; Exocytosis; In Vitro Techniques; Kinetics; Male; Mast Cells; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Serotonin; Timolol | 1997 |
Autonomic components of the cardiovascular responses to an acoustic startle stimulus in rats.
Topics: Acoustic Stimulation; Adrenergic alpha-Antagonists; Animals; Atenolol; Atropine Derivatives; Autonomic Nerve Block; Autonomic Nervous System; Blood Pressure; Evaluation Studies as Topic; Evoked Potentials, Auditory; Heart Rate; Hemodynamics; Male; Parasympatholytics; Prazosin; Random Allocation; Rats; Rats, Wistar; Sympatholytics | 1997 |
Contribution of the autonomic nervous system to blood pressure and heart rate variability changes in early experimental hyperthyroidism.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Heart Rate; Hyperthyroidism; Male; Prazosin; Rats; Rats, Wistar; Stress, Physiological; Thyroxine | 1998 |
Quantification of sympathetic and parasympathetic tones by nonlinear indexes in normotensive rats.
Topics: Animals; Atenolol; Atropine; Blood Pressure; Diastole; Hexamethonium; Male; Parasympathetic Nervous System; Prazosin; Rats; Rats, Inbred WKY; Reference Values; Sympathetic Nervous System; Systole | 1998 |
Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism.
Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart Rate; Hyperthyroidism; Male; Prazosin; Rats; Rats, Wistar; Tachycardia; Thyroid Hormones; Thyroxine; Vagus Nerve | 1998 |
Involvement of alpha1-adrenoceptors in the basolateral amygdala in modulation of memory storage.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amygdala; Animals; Atenolol; Avoidance Learning; Male; Memory; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine | 1999 |
Sphingosine 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart.
Topics: Adenylyl Cyclases; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atenolol; Coronary Circulation; Dogs; Female; Lysophospholipids; Male; Myocardial Contraction; Myocardium; Perfusion; Prazosin; Second Messenger Systems; Sphingosine; Tachycardia, Sinus | 2000 |
Influence of sympathetic heart rate modulation on RT interval rate adaptation in conscious dogs.
Topics: Acoustic Stimulation; Adaptation, Physiological; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Atrial Function; Cardiac Pacing, Artificial; Consciousness; Dogs; Electrocardiography; Heart; Heart Rate; Prazosin; Sympathetic Nervous System | 2000 |
Antihypertensive monotherapy and cardiovascular responses to an acoustic startle stimulus.
Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Analysis of Variance; Antihypertensive Agents; Atenolol; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Prazosin; Reflex, Startle; Stroke Volume; Vascular Resistance | 2001 |
A N-terminal PTHrP peptide fragment void of a PTH/PTHrP-receptor binding domain activates cardiac ET(A) receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Cell Separation; Endothelin Receptor Antagonists; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Parathyroid Hormone-Related Protein; Peptides, Cyclic; Phenylephrine; Prazosin; Proteins; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Receptors, Parathyroid Hormone; Vasoconstrictor Agents; Viper Venoms | 2001 |
Comparison of skin permeability of drugs in mice and human cadaver skin.
Topics: Administration, Cutaneous; Adult; Animals; Atenolol; Cadaver; Epidermis; Humans; Male; Mice; Minoxidil; Permeability; Prazosin; Propranolol; Skin Absorption; Species Specificity | 2000 |
Enhancer aided in vitro permeation of atenolol and prazosin hydrochloride through mice skin.
Topics: Administration, Cutaneous; Animals; Atenolol; Dimethyl Sulfoxide; Dimethylformamide; Ethanol; Fatty Alcohols; Mice; Prazosin; Skin Absorption | 2001 |
Altered melatonin production in TGR(mREN2)27 rats: on the regulation by adrenergic agonists, antagonists and angiotensin II in cultured pinealocytes.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Angiotensin II; Animals; Animals, Genetically Modified; Atenolol; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Norepinephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2001 |
Elevated sympathetic nervous activity in mice deficient in alphaCGRP.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Baroreflex; Blood Pressure; Calcitonin Gene-Related Peptide; Gene Targeting; Heart Rate; Mice; Mice, Knockout; Muscarinic Antagonists; Prazosin; Sympathetic Nervous System; Vascular Resistance | 2001 |
Effect of physicochemical parameters on skin permeability of antihypertensive.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Atenolol; Chemical Phenomena; Chemistry, Physical; Diltiazem; Female; In Vitro Techniques; Mice; Permeability; Prazosin; Propranolol; Reserpine; Skin | 2001 |
Dietary Mg(2+) supplementation restores impaired vasoactive responses in isolated rat aorta induced by chronic ethanol consumption.
Topics: Animals; Aorta, Thoracic; Atenolol; Blood Pressure; Body Weight; Dietary Supplements; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Female; In Vitro Techniques; Magnesium; Male; Nitroprusside; Norepinephrine; Potassium Chloride; Prazosin; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Changes in blood pressure and heart rate by repetitive transcranial magnetic stimulation in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Autonomic Nervous System; Blood Pressure; Electric Stimulation; Heart Rate; Male; Prazosin; Rats; Rats, Inbred WKY; Transcranial Magnetic Stimulation | 2002 |
For the patient. New treatments for heart failure in Black people. Adjunctive sympathoplegic therapy to ACE inhibition in Blacks with congestive heart failure: a comparison of alpha-1 with beta-1 blockade on exercise tolerance and cardiac sympathovagal re
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Black People; Clinical Trials as Topic; Drug Therapy, Combination; Enalapril; Exercise Tolerance; Heart Failure; Humans; Hypertension; Nigeria; Prazosin; Renin-Angiotensin System | 2003 |
The beta3-adrenoceptor-mediated relaxation induced by dopamine in guinea pig taenia caecum.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzazepines; Butoxamine; Cecum; Dopamine; Dopamine Antagonists; Guinea Pigs; Haloperidol; Male; Muscle Relaxation; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic, beta-3; Yohimbine | 2003 |
Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.
Topics: 3,3'-Diaminobenzidine; Animals; Argentina; Aspirin; Atenolol; Butoxamine; Dinoprostone; Dobutamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Forecasting; Larrea; Masoprocol; Peroxidase; Plant Extracts; Plant Leaves; Prazosin; Propranolol; Rats; Rats, Wistar; Submandibular Gland; Water | 2004 |
Hypertension and insulin resistance are not directly related in obese dogs.
Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System | 2004 |
Sympathetic and angiotensin-dependent hypertension during cage-switch stress in mice.
Topics: Angiotensins; Animals; Atenolol; Blood Pressure; Heart Rate; Housing, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Motor Activity; Prazosin; Stress, Psychological; Sympathetic Nervous System | 2004 |
Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ataxin-3; Atenolol; Baroreflex; Blood Pressure; Bradycardia; Consciousness; Deep Brain Stimulation; Female; Heart Rate; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Muscle, Skeletal; Neurons; Neuropeptides; Nuclear Proteins; Orexins; Phenylephrine; Prazosin; Transcription Factors; Vasodilation | 2006 |
Optimal frequency ranges for extracting information on cardiovascular autonomic control from the blood pressure and pulse interval spectrograms in mice.
Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovascular Physiological Phenomena; Heart Rate; Hydralazine; Male; Mice; Mice, Inbred C57BL; Parasympathomimetics; Prazosin; Signal Processing, Computer-Assisted; Sympatholytics; Telemetry; Vasodilation; Vasodilator Agents | 2007 |
Peculiarities of regulation of heart rate and stroke volume in rats during ontogeny.
Topics: Adrenergic Antagonists; Age Factors; Animals; Atenolol; Atropine; Cardiac Output; Heart Rate; Muscarinic Antagonists; Phentolamine; Plethysmography, Impedance; Prazosin; Propranolol; Rats; Stroke Volume | 2006 |
Applicability of recent methods used to estimate spontaneous baroreflex sensitivity to resting mice.
Topics: Algorithms; Animals; Antihypertensive Agents; Atenolol; Atropine; Baroreflex; Blood Pressure; Fourier Analysis; Hydralazine; Male; Mice; Mice, Inbred C57BL; Parasympatholytics; Prazosin; Pulse; Rest | 2008 |
Complex adrenergic and inflammatory mechanisms contribute to phase 2 ventricular arrhythmias in anaesthetized rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Catecholamines; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Heart Rate; Leukocyte Count; Male; Neutrophil Infiltration; Neutrophils; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic | 2009 |
Contractile response of norepinephrine is modulated by caspase-3 in adult rat ventricular myocytes isolated from septic rat heart.
Topics: Adrenergic alpha-Agonists; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Atenolol; Caspase 3; Cells, Cultured; Gene Expression; Male; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Prazosin; Quinolines; Rats; Rats, Sprague-Dawley; Sepsis | 2009 |
Restoration of neutrophil immunocompetence after cardiopulmonary bypass by beta-adrenergic blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Butoxamine; Catecholamines; Coronary Artery Bypass; Cytokines; Epinephrine; Flow Cytometry; Free Radicals; Humans; Immunocompetence; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Naphthyridines; Neutrophils; Pindolol; Prazosin | 2010 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment | 2011 |
Hemodynamic responses to aortic depressor nerve stimulation in conscious L-NAME-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Atenolol; Atropine Derivatives; Baroreflex; Blood Pressure; Electric Stimulation; Heart Rate; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Parasympatholytics; Prazosin; Rats; Rats, Wistar | 2011 |
Central and peripheral mechanisms underlying gastric distention inhibitory reflex responses in hypercapnic-acidotic rats.
Topics: Acidosis; Adrenergic alpha-1 Receptor Antagonists; Anesthetics; Animals; Atenolol; Atropine Derivatives; Blood Pressure; Bradycardia; Gastric Dilatation; Heart Rate; Hypercapnia; Kainic Acid; Male; Medulla Oblongata; Parasympathetic Nervous System; Parasympatholytics; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex; Sympathetic Nervous System; Sympatholytics | 2011 |
Sleep disturbance among spontaneously hypertensive rats is mediated by an α1-adrenergic mechanism.
Topics: Animals; Atenolol; Blood Pressure; Male; Prazosin; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Sleep; Sleep Wake Disorders | 2012 |
Unstable sleep and higher sympathetic activity during late-sleep periods of rats: implication for late-sleep-related higher cardiovascular events.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; Baroreflex; Blood Pressure; Electroencephalography; Male; Polysomnography; Prazosin; Rats; Rats, Inbred WKY; Sleep; Sleep Deprivation | 2013 |
Effects of hippadine on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats.
Topics: Amaryllidaceae Alkaloids; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Crinum; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hypertension; Male; Medicine, African Traditional; Prazosin; Rats; Rats, Inbred SHR; Rats, Wistar; South Africa | 2014 |
Involvement of alpha- and beta-adrenoceptors in the automaticity of the isolated guinea pig pulmonary vein myocardium.
Topics: Animals; Atenolol; Atrial Fibrillation; Carbazoles; Carvedilol; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocardium; Norepinephrine; Prazosin; Propanolamines; Pulmonary Veins; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction | 2017 |
Rat mesenteric small artery neurogenic dilatation is predominantly mediated by β
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Antinematodal Agents; Atenolol; Male; Mesenteric Arteries; Piperazines; Prazosin; Quinazolines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Suramin; Tissue Culture Techniques; Vasoconstriction; Vasodilation | 2019 |
Augmented blood pressure variability following continuous infusion of noradrenaline in rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Atenolol; Blood Pressure; Heart Rate; Isoproterenol; Male; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Sympathetic Nervous System | 2020 |