Page last updated: 2024-08-23

pravastatin and niacin

pravastatin has been researched along with niacin in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.03)	18.7374
1990's	14 (42.42)	18.2507
2000's	11 (33.33)	29.6817
2010's	7 (21.21)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Imai, K; Kobayashi, D; Nezu, J; Nozawa, T; Tamai, I; Tsuji, A	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Brown, WV; Karmally, W; Smith, DA	1
Cooper, ME; Jerums, G; Panagiotopoulos, S; Sinha, A; Tsalamandris, C	1
Harris, WS; Nelson, J; O'Keefe, JH; Windsor, SL	1
Higashida, H; Maeda, H; Ogihara, T; Sai, Y; Takanaga, H; Tamai, I; Tsuji, A	1
Gibson, CM; Pasternak, RC; Rosner, B; Sacks, FM; Stone, PH	1
Connelly, PW; Davignon, J; Gagné, C; Hayden, MR; Hegele, R; Lupien, PJ; McPherson, R; Montigny, M; Roederer, G; Tan, MH	1
Bambauer, R; Müller, UA; Schiel, R	1
Grundy, SM; Mostaza, JM; Schulz, I; Vega, GL	1
Fonseca, VA; Gardner, SF; Granberry, MC; Marx, MA; Skelton, DR; White, LM	1
Grundy, SM	1
Wehmeier, T; Ziajka, PE	1
Sinzinger, H	1
Applegate, W; Crouse, J; Davis, KB; Egan, DA; Elam, MB; Garg, R; Herd, JA; Hunninghake, DB; Kostis, JB; Pettinger, MB; Probstfield, J; Sheps, DS; Waclawiw, MA; Wilt, TJ	1
Davis, KB; Egan, DA; Garg, R; Griffin, B; Pettinger, MB; Thomason, T; Waclawiw, MA	1
Agrawal, R; Arntz, HR; Fischer, F; Linderer, T; Schnitzer, L; Schultheiss, HP; Stern, R; Wunderlich, W	1
Hsu, JC; Kashyap, ML; Sikand, G; Wong, ND	1
Applegate, WB; Crouse, JR; Davis, KB; Egan, D; Elam, MB; Garg, R; Herd, JA; Hunninghake, DB; Johnson, WC; Kennedy, JW; Kostis, JB; Sheps, DS	1
Agrawal, R; Arntz, HR; Fischer, F; Schnitzer, L; Schultheiss, HP; Stern, R; Wunderlich, W	1
Stein, EA	1
de Boer, A; Fishman, PA; Heckbert, SR; Klungel, OH; Leufkens, HG; Psaty, BM; Sullivan, SD; Veenstra, DL	1
Blazing, MA; Duvall, WL; Guyton, JR; Saxena, S	1
Lipton, AM; Lutjohann, D; Moore, C; Svetlik, D; Vega, GL; Von Bergmann, K; Weiner, MF	1
Baskin, F; Fang, X; Hynan, LS; Moore, CB; Rosenberg, RN; Vega, GL; Weiner, M	1
Hess, L; Krähenbühl, S; Krähenbühl-Melcher, A; Rätz Bravo, AE; Schlienger, RG; Tchambaz, L	1
Alsheikh-Ali, AA; Karas, RH	1
Charles, MA; Ishida, B; Kane, JP; Malloy, MJ; Pan, J; Shilian, P; Wu, X	1

Reviews

5 review(s) available for pravastatin and niacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Consensus statement: Role of therapy with "statins" in patients with hypertriglyceridemia. The American journal of cardiology, 1998, Feb-26, Volume: 81, Issue:4A Topics: Cholesterol, HDL; Cholesterol, VLDL; Clinical Trials as Topic; Consensus Development Conferences as Topic; Coronary Disease; Drug Therapy, Combination; Exercise; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Triglycerides; Weight Loss	1998
Peripheral neuropathy and lipid-lowering therapy. Southern medical journal, 1998, Volume: 91, Issue:7 Topics: Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Naphthalenes; Niacin; Peripheral Nervous System Diseases; Pravastatin; Pyrroles; Simvastatin	1998
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis]. Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38 Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis	1998
Managing dyslipidemia in the high-risk patient. The American journal of cardiology, 2002, Mar-07, Volume: 89, Issue:5A Topics: Adult; Anticholesteremic Agents; Atorvastatin; Bile Acids and Salts; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Indoles; Lovastatin; Niacin; Practice Guidelines as Topic; Pravastatin; Pyrimidines; Pyrroles; Risk; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome; United States	2002

Trials

14 trial(s) available for pravastatin and niacin

Article	Year
Complementary effects of pravastatin and nicotinic acid in the treatment of combined hyperlipidaemia in diabetic and non-diabetic patients. Journal of cardiovascular risk, 1994, Volume: 1, Issue:3 Topics: Adult; Aged; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hyperlipidemias; Male; Middle Aged; Niacin; Pravastatin; Treatment Outcome; Triglycerides	1994
Effects of pravastatin with niacin or magnesium on lipid levels and postprandial lipemia. The American journal of cardiology, 1995, Sep-01, Volume: 76, Issue:7 Topics: Adult; Apolipoprotein A-I; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Eating; Humans; Hypertriglyceridemia; Lipids; Magnesium; Niacin; Pravastatin; Risk Factors; Triglycerides	1995
Effect on coronary atherosclerosis of decrease in plasma cholesterol concentrations in normocholesterolaemic patients. Harvard Atherosclerosis Reversibility Project (HARP) Group. Lancet (London, England), 1994, Oct-29, Volume: 344, Issue:8931 Topics: Anticholesteremic Agents; Cardiac Catheterization; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Gemfibrozil; Humans; Lipids; Male; Middle Aged; Niacin; Pravastatin; Treatment Outcome	1994
Comparative efficacy and safety of pravastatin, nicotinic acid and the two combined in patients with hypercholesterolemia. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Drug Combinations; Female; Flushing; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Nausea; Niacin; Placebos; Pravastatin; Single-Blind Method; Triglycerides	1994
Four years' treatment efficacy of patients with severe hyperlipidemia. Lipid lowering drugs versus LDL-apheresis. The International journal of artificial organs, 1995, Volume: 18, Issue:12 Topics: Adolescent; Adult; Anticholesteremic Agents; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Longitudinal Studies; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Quality of Life	1995
Comparison of pravastatin with crystalline nicotinic acid monotherapy in treatment of combined hyperlipidemia. The American journal of cardiology, 1997, May-01, Volume: 79, Issue:9 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Humans; Hyperlipidemias; Middle Aged; Niacin; Pravastatin; Risk Factors; Triglycerides	1997
Combination of low-dose niacin and pravastatin improves the lipid profile in diabetic patients without compromising glycemic control. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fructosamine; Humans; Hypercholesterolemia; Lipoprotein(a); Male; Middle Aged; Niacin; Pravastatin; Prospective Studies	1997
Compliance to multiple interventions in a high risk population. Annals of epidemiology, 1999, Volume: 9, Issue:7 Topics: Adult; Aged; Anticholesteremic Agents; Anticoagulants; Antioxidants; Aspirin; Data Interpretation, Statistical; Double-Blind Method; Female; Humans; Male; Niacin; Patient Compliance; Peripheral Vascular Diseases; Placebos; Platelet Aggregation Inhibitors; Pravastatin; Time Factors; Warfarin	1999
[Short- and long-term effects of intensified versus conventional antilipidemic therapy in patients with coronary heart disease. Results from the Lipid-Coronary Artery Disease (L-CAD) Study]. Zeitschrift fur Kardiologie, 1999, Volume: 88, Issue:8 Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Coronary Disease; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Niacin; Pravastatin; Prospective Studies; Treatment Outcome	1999
Effective and safe modification of multiple atherosclerotic risk factors in patients with peripheral arterial disease. American heart journal, 2000, Volume: 140, Issue:5 Topics: Aged; Anticholesteremic Agents; Anticoagulants; Antioxidants; Arteriosclerosis; Aspirin; Cholesterol, LDL; Feasibility Studies; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Niacin; Platelet Aggregation Inhibitors; Pravastatin; Risk Factors; Self Medication; Time Factors; Treatment Outcome; Triglycerides; Vitamins; Warfarin	2000
Beneficial effects of pravastatin (+/-colestyramine/niacin) initiated immediately after a coronary event (the randomized Lipid-Coronary Artery Disease [L-CAD] Study). The American journal of cardiology, 2000, Dec-15, Volume: 86, Issue:12 Topics: Adult; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Chemoprevention; Chi-Square Distribution; Cholesterol, LDL; Cholestyramine Resin; Confidence Intervals; Coronary Angiography; Coronary Artery Disease; Coronary Disease; Coronary Vessels; Drug Combinations; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Niacin; Odds Ratio; Peripheral Vascular Diseases; Pravastatin; Regression Analysis; Statistics, Nonparametric; Stroke; Survival Rate; Treatment Outcome	2000
Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. Archives of neurology, 2003, Volume: 60, Issue:4 Topics: Aged; Alzheimer Disease; Brain; Cholesterol 24-Hydroxylase; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Simvastatin; Steroid Hydroxylases; Treatment Outcome	2003
Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients. Neurology, 2003, Jun-24, Volume: 60, Issue:12 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Blood Platelets; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Niacin; Pravastatin; Protein Processing, Post-Translational; Simvastatin; Single-Blind Method	2003
Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes. Metabolism: clinical and experimental, 2011, Volume: 60, Issue:2 Topics: Aged; Apolipoprotein A-I; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; High-Density Lipoproteins, Pre-beta; Humans; Hypolipidemic Agents; Lipids; Male; Middle Aged; Niacin; Pravastatin; Retrospective Studies; Simvastatin	2011

Other Studies

14 other study(ies) available for pravastatin and niacin

Article	Year
Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2 Topics: Biological Transport; Carbon Radioisotopes; Cell Membrane; Cells, Cultured; Estrone; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Intestine, Small; Organic Anion Transporters; Pravastatin; Radiopharmaceuticals; Time Factors; Tritium	2003
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Treating hyperlipidemia, Part III: Drug therapy. Geriatrics, 1987, Volume: 42, Issue:8 Topics: Aged; Enzyme Inhibitors; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Pravastatin	1987
Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids. Biochemical and biophysical research communications, 1995, Sep-14, Volume: 214, Issue:2 Topics: Animals; Biological Transport; Carboxylic Acids; Carrier Proteins; CHO Cells; Cricetinae; Female; Hydrogen-Ion Concentration; Ibuprofen; Intestinal Mucosa; Lactates; Mandelic Acids; Membrane Proteins; Monocarboxylic Acid Transporters; Niacin; Oocytes; Pravastatin; Propionates; Protons; Rabbits; Recombinant Proteins; RNA, Complementary; RNA, Messenger; Stereoisomerism; Transcription, Genetic; Transfection; Valproic Acid; Xenopus laevis	1995
Rationale and design of the Arterial Disease Multiple Intervention Trial (ADMIT) pilot study. The American journal of cardiology, 1999, Feb-15, Volume: 83, Issue:4 Topics: Adult; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Niacin; Peripheral Vascular Diseases; Pilot Projects; Pravastatin; Randomized Controlled Trials as Topic; Research Design	1999
Dietitian intervention improves lipid values and saves medication costs in men with combined hyperlipidemia and a history of niacin noncompliance. Journal of the American Dietetic Association, 2000, Volume: 100, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cost-Benefit Analysis; Dietary Services; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids; Male; Medical Records; Middle Aged; Niacin; Pravastatin; Retrospective Studies; Time Factors; Treatment Refusal; Triglycerides	2000
Lipid-lowering drug use and cardiovascular events after myocardial infarction. The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5 Topics: Cholesterol; Clofibrate; Cohort Studies; Coronary Artery Disease; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Myocardial Infarction; Niacin; Pravastatin; Risk Factors; Simvastatin; Stroke; Treatment Outcome	2002
Targeting cardiovascular risk associated with both low density and high density lipoproteins using statin-niacin combination therapy. Journal of cardiovascular risk, 2002, Volume: 9, Issue:6 Topics: Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Coronary Disease; Drug Therapy, Combination; Female; Flushing; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Niacin; Pravastatin; Retrospective Studies; Risk Factors; Treatment Outcome	2002
Prevalence of potentially severe drug-drug interactions in ambulatory patients with dyslipidaemia receiving HMG-CoA reductase inhibitor therapy. Drug safety, 2005, Volume: 28, Issue:3 Topics: Aged; Ambulatory Care; Aryl Hydrocarbon Hydroxylases; Atorvastatin; Comorbidity; Cross-Sectional Studies; Cyclosporine; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Indoles; Male; Niacin; Oxidoreductases, N-Demethylating; Physicians; Pravastatin; Prevalence; Product Surveillance, Postmarketing; Pyrroles; Simvastatin; Time Factors	2005
Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system). The American journal of cardiology, 2007, Feb-01, Volume: 99, Issue:3 Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Chemical and Drug Induced Liver Injury; Drug Prescriptions; Drug Therapy, Combination; Dyslipidemias; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Diseases; Lovastatin; Niacin; Pravastatin; Prevalence; Pyrroles; Retrospective Studies; Rhabdomyolysis; Risk Factors; Simvastatin; United States; United States Food and Drug Administration	2007

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