Compounds > piperidine
Page last updated: 2024-08-18

piperidine and urea

piperidine has been researched along with urea in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's6 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roy, K; Thomas Leonard, J1
Brady, AE; Bridges, TM; Conn, PJ; Daniels, RN; Lindsley, CW; Miller, NR1
Ahn, K; Beidler, D; Bhattacharya, K; Cravatt, BF; Johnson, DS; Kamtekar, S; Lazerwith, S; Liimatta, M; Long, JZ; McKinney, MK; Mileni, M; Sadagopan, N; Smith, SE; Stevens, RC; Stiff, C; Swaney, S; Van Becelaere, K; Weerapana, E; Zhang, Y1
Alonso-Galicia, M; Berger, JP; Chen, HS; Chen, Y; Colletti, SL; Deng, Q; Ding, FX; Pai, LY; Roy, S; Shen, HC; Tata, JR; Tong, V; Tong, X; Xu, S; Zhang, B; Zhang, X; Zhou, G1
De Lombaert, S; Eldrup, AB; Farrow, NA; Kukulka, A; Soleymanzadeh, F1
D'Anna, F; Frenna, V; Ghelfi, F; Marullo, S; Spinelli, D1
Deng, SX; Hammock, BD; Morisseau, C; Newcomer, ME; Pakhomova, S; Pecic, S; Rinderspacher, A; Zhu, Z1
Aaltonen, N; Häyrinen, J; Käsnänen, H; Korhonen, J; Kuusisto, A; Laitinen, JT; Laitinen, T; Lehtonen, M; Navia-Paldanius, D; Nevalainen, T; Pantsar, T; Pasonen-Seppänen, S; Poso, A; Ribas, CR; Rönkkö, J; Savinainen, JR; Takabe, P1
Conway, JG; Demarest, KT; Gaul, MD; Ho, G; Kuo, GH; Lenhard, JM; Li, Y; Liang, Y; Lu, H; Murray, WV; Tang, Y; Yang, SM; Zhang, R1
Chang, M; Hua, J; Huang, CS; L'Heureux, A; Lam, PY; Lapointe, P; Martel, A; Price, LA; Qiao, JX; Rehfuss, R; Ruel, R; Thibeault, C; Wexler, RR; Wu, Q; Zheng, J1

Other Studies

10 other study(ies) available for piperidine and urea

ArticleYear
Comparative QSAR modeling of CCR5 receptor binding affinity of substituted 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas.
    Bioorganic & medicinal chemistry letters, 2006, Sep-01, Volume: 16, Issue:17

    Topics: Amides; Piperidines; Quantitative Structure-Activity Relationship; Receptors, CCR5; Urea

2006
Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen.
    Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20

    Topics: Allosteric Regulation; Allosteric Site; Amides; Benzimidazoles; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Chemical; Nitrogen; Piperidines; Receptor, Muscarinic M1; Structure-Activity Relationship; Sulfonamides; Urea

2008
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.
    Chemistry & biology, 2009, Apr-24, Volume: 16, Issue:4

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Brain; Crystallography, X-Ray; Endocannabinoids; Enzyme Inhibitors; Humans; Male; Pain; Piperazine; Piperazines; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Structure-Activity Relationship; Urea

2009
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, Sep-15, Volume: 19, Issue:18

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Blood Pressure; Epoxide Hydrolases; Humans; Hypertension; Models, Molecular; Piperidines; Protein Binding; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Urea

2009
Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Administration, Oral; Animals; Binding Sites; Computer Simulation; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Microsomes, Liver; Piperidines; Rats; Urea

2010
Acid- and base-catalysis in the mononuclear rearrangement of some (Z)-arylhydrazones of 5-amino-3-benzoyl-1,2,4-oxadiazole in toluene: effect of substituents on the course of reaction.
    The Journal of organic chemistry, 2011, Apr-15, Volume: 76, Issue:8

    Topics: Alkalies; Amines; Biological Products; Catalysis; Dioxanes; Hydrazones; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Oxadiazoles; Piperidines; Structure-Activity Relationship; Temperature; Toluene; Trichloroacetic Acid; Urea; Water

2011
Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors.
    Bioorganic & medicinal chemistry letters, 2013, Jan-15, Volume: 23, Issue:2

    Topics: Anti-Inflammatory Agents; Catalytic Domain; Epoxide Hydrolases; Humans; Inhibitory Concentration 50; Microsomes, Liver; Models, Molecular; Molecular Structure; Piperidines; Protease Inhibitors; Solubility; Structure-Activity Relationship; Urea; Vasodilator Agents

2013
Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase.
    Chemistry & biology, 2013, Mar-21, Volume: 20, Issue:3

    Topics: Animals; Benzodioxoles; Enzyme Inhibitors; HEK293 Cells; Humans; Mice; Monoacylglycerol Lipases; Piperazine; Piperazines; Piperidines; Rats; Substrate Specificity; Triazoles; Urea

2013
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Administration, Oral; Animals; Body Weight; Diet; Enzyme Activation; Enzyme Inhibitors; Mice; Mice, Inbred C57BL; Obesity; Piperidines; Protein Binding; Rats; Stearoyl-CoA Desaturase; Structure-Activity Relationship; Urea

2013
Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Adenosine Diphosphate; Amines; Animals; Blood Platelets; Half-Life; Humans; Microsomes, Liver; Piperidines; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Agonists; Rats; Receptors, Purinergic P2Y1; Structure-Activity Relationship; Urea

2013