pd 142893 has been researched along with bq 123 in 18 studies
| Studies (pd 142893) | Trials (pd 142893) | Recent Studies (post-2010) (pd 142893) | Studies (bq 123) | Trials (bq 123) | Recent Studies (post-2010) (bq 123) |
|---|---|---|---|---|---|
| 64 | 0 | 3 | 1,391 | 63 | 152 |
| Protein | Taxonomy | pd 142893 (IC50) | bq 123 (IC50) |
|---|---|---|---|
| Endothelin-1 receptor | Homo sapiens (human) | 0.017 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 0.014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allcock, GH; Corder, R; Mickley, EJ; Vane, JR; Warner, TD | 1 |
| Mayhan, WG; Rubinstein, I | 1 |
| Nambi, P; Ohlstein, EH; Semler, DE; Slater, C; Stern, PH | 1 |
| Beck, GR; Douglas, SA; Elliott, JD; Feuerstein, G; Gleason, JG; Lago, MA; Nambi, P; Ohlstein, EH; Ruffolo, RR | 1 |
| Battistini, B; Corder, R; Doherty, AM; Warner, TD | 1 |
| Cody, WL; Davis, LS; Doherty, AM; Haleen, SJ; Keiser, JA | 1 |
| Allcock, GH; Corder, R; Vane, JR; Warner, TD | 1 |
| Allcock, GH; Mickley, EJ; Vane, JR; Warner, TD | 1 |
| de Wit, D; Kimura, S; Masaki, T; Masuda, Y; Mizuguchi, T; Moroi, K; Nishiyama, M; Saito, T; Tanaka, H; Yanagisawa, M | 1 |
| Cheng, XM; Flynn, MA; Haleen, SJ; Reynolds, EE; Welch, KM | 1 |
| Alvarez, BV; Camilión de Hurtado, MC; Cingolani, HE; Ennis, IL | 1 |
| Alvarez, BV; Cingolani, HE; de Hurtado, MC; Ennis, IL | 1 |
| Goto, K | 1 |
| Asham, E; Boulos, PB; Burnstock, G; Fredericks, S; Loizidou, M; Miller, K; Shankar, A; Taylor, I | 1 |
| Gardner, A; Hoang, D; Macarthur, H; Westfall, TC | 1 |
| Chebanu, LM; Chebanu, NV; Ivanov, VM; Kobets, VA; Moraru, IL; Popovich, IM; Popovich, MI; Todirash, MP | 1 |
| Amon, M; Bächle, A; Harder, Y; Menger, MD; Mörsdorf, P; Pittet, B; Wettstein, R | 1 |
| Meoli, DF; White, RJ | 1 |
2 review(s) available for pd 142893 and bq 123
| Article | Year |
|---|---|
Endothelin receptor antagonists: actions and rationale for their development.
Topics: Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Disease Models, Animal; Drug Design; Endothelin Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Humans; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Pyrimidines; Receptors, Endothelin; Sulfonamides | 1994 |
[Endothelin receptors].
Topics: Animals; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; GTP-Binding Proteins; Humans; Oligopeptides; Peptides, Cyclic; Piperidines; Receptors, Endothelin; Signal Transduction | 2000 |
16 other study(ies) available for pd 142893 and bq 123
| Article | Year |
|---|---|
Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors.
Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Endothelin Receptor Antagonists; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Muscle, Smooth; Muscle, Smooth, Vascular; Oligopeptides; Peptides, Cyclic; Rabbits; Rats; Rats, Wistar; Vasodilator Agents; Viper Venoms | 1993 |
Effects of endothelin receptor antagonists on bradykinin-induced increases in macromolecular efflux.
Topics: Animals; Bradykinin; Calcium; Capillary Permeability; Cricetinae; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Male; Microscopy, Fluorescence; Oligopeptides; Peptides, Cyclic; Receptors, Endothelin; Venules | 1994 |
Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Calcium; Cell Line; Cell Membrane; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Osteosarcoma; Peptides, Cyclic; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Viper Venoms | 1995 |
Nonpeptide endothelin receptor antagonists. II. Pharmacological characterization of SB 209670.
Topics: Adult; Animals; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Female; Humans; In Vitro Techniques; Indans; Male; Middle Aged; Oligopeptides; Peptides, Cyclic; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vasoconstriction | 1994 |
Effects of selective endothelin antagonists on the hemodynamic response to cyclosporin A.
Topics: Animals; Blood Pressure; Cyclosporine; Endothelin Receptor Antagonists; Hemodynamics; Kidney; Male; Oligopeptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renal Circulation; Vascular Resistance | 1994 |
Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF.
Topics: Amino Acid Sequence; Animals; Aorta, Thoracic; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Oligopeptides; Peptides, Cyclic; Pulmonary Artery; Rabbits; Rats; Rats, Wistar; Receptors, Endothelin; Stomach; Vasoconstrictor Agents; Vasodilation; Viper Venoms | 1993 |
Characterization of endothelin receptors mediating the effects of the endothelin/sarafotoxin peptides on autonomic neurotransmission in the rat vas deferens and guinea-pig ileum.
Topics: Amino Acid Sequence; Animals; Autonomic Nervous System; Electric Stimulation; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Oligopeptides; Peptides, Cyclic; Rats; Rats, Wistar; Receptors, Endothelin; Synaptic Transmission; Vas Deferens; Vasoconstrictor Agents; Viper Venoms | 1993 |
Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse.
Topics: Animals; Aorta; Endothelin-1; Gastric Fundus; In Vitro Techniques; Mice; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Oligopeptides; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin B; Receptors, Endothelin | 1997 |
Endothelin B receptors on human endothelial and smooth-muscle cells show equivalent binding pharmacology.
Topics: Binding, Competitive; Bosentan; Cells, Cultured; Endothelin Receptor Antagonists; Endothelium, Vascular; Humans; Immunohistochemistry; Indicators and Reagents; Muscle, Smooth, Vascular; Oligopeptides; Peptides, Cyclic; Radioligand Assay; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides | 1998 |
Stretch-induced alkalinization of feline papillary muscle: an autocrine-paracrine system.
Topics: Alkalies; Alkaloids; Amiloride; Angiotensin II; Animals; Anti-Arrhythmia Agents; Autocrine Communication; Benzophenanthridines; Cats; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Heart; Hydrogen-Ion Concentration; Losartan; Muscle Contraction; Muscle Fibers, Skeletal; Oligopeptides; Papillary Muscles; Paracrine Communication; Peptides, Cyclic; Phenanthridines; Protein Kinase C; Sodium-Hydrogen Exchangers | 1998 |
Stimulation of myocardial Na(+)-independent Cl(-)-HCO(3)(-) exchanger by angiotensin II is mediated by endogenous endothelin.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Alkalies; Angiotensin II; Animals; Antiporters; Bicarbonates; Buffers; Carbon Dioxide; Cats; Chloride-Bicarbonate Antiporters; Endothelin Receptor Antagonists; Endothelins; Hydrogen-Ion Concentration; Methylamines; Myocardium; Oligopeptides; Peptides, Cyclic; Rats; Receptor, Endothelin A; Sodium | 2000 |
Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET(A) receptor antagonism.
Topics: Adult; Aged; Aged, 80 and over; Animals; Colon; Colorectal Neoplasms; Endothelin Receptor Antagonists; Endothelin-1; Female; Humans; Immunohistochemistry; Liver Neoplasms; Male; Middle Aged; Neoplasm Transplantation; Neoplasms, Experimental; Oligopeptides; Peptides, Cyclic; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B | 2001 |
Endothelin-induced modulation of neuropeptide Y and norepinephrine release from the rat mesenteric bed.
Topics: Animals; Antihypertensive Agents; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Male; Mesenteric Arteries; Neuropeptide Y; Norepinephrine; Oligopeptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstrictor Agents; Viper Venoms | 2002 |
[Changes of activity of the endothelial system in experimental heart failure].
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Norepinephrine; Oligopeptides; Peptides, Cyclic; Rats; Vasoconstriction; Ventricular Function, Left | 2005 |
Selective blockade of endothelin-B receptor improves survival of critically perfused musculocutaneous flaps.
Topics: Animals; Arterioles; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Graft Survival; Ischemia; Mice; Mice, Inbred C57BL; Microcirculation; Microscopy, Fluorescence; Models, Animal; Necrosis; Oligopeptides; Peptides, Cyclic; Piperidines; Regional Blood Flow; Surgical Flaps; Time Factors; Venules | 2007 |
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase.
Topics: Animals; Antihypertensive Agents; Aorta; Becaplermin; Cell Line; Cell Movement; Cells, Cultured; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Peptides, Cyclic; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Signal Transduction; Tunica Media | 2010 |