paraoxon and sarin
paraoxon has been researched along with sarin in 29 studies
Research
Studies (29)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.79) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 12 (41.38) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Fonnum, F; Lund-Karlsen, R | 1 |
| Maxwell, DM | 1 |
| Eldefrawi, AT; Eldefrawi, ME; Silveira, CL | 1 |
| Flynn, CJ; Wecker, L | 1 |
| Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K | 1 |
| Broomfield, CA; Platteborze, PL | 1 |
| Koca, J; Ornstein, RL; Rittenhouse, RC; Zhan, CG | 1 |
| DECANDOLE, CA; McPHAIL, MK | 1 |
| COOPER, PL; KRACKOW, EH; OWENS, EJ; PUNTE, CL | 1 |
| Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA | 1 |
| Kellar, KJ | 1 |
| Amine, A; Arduini, F; Moscone, D; Palleschi, G; Ricci, F | 1 |
| Bumm, R; Eckert, S; Eyer, P; Herkert, N; Thiermann, H; Weber, G; Worek, F | 1 |
| Bahnson, BJ; Cerasoli, DM; Epstein, TM; Kirby, SD; Samanta, U | 1 |
| Clarençon, D; Herkert, NM; Lallement, G; Thiermann, H; Worek, F | 1 |
| Aurbek, N; Eyer, P; Herkert, NM; Thiermann, H; Worek, F | 1 |
| Cabal, J; Holas, O; Karasova, JZ; Korabecny, J; Kuca, K; Pikula, J; Pohanka, M | 1 |
| Thiermann, H; Wille, T; Worek, F | 1 |
| Amitai, G; Barry Sharpless, K; Berend, S; Fokin, VV; Garcia, E; Kovarik, Z; Radić, Z; Sit, RK; Taylor, P; Zhang, L | 1 |
| Fan, K; Feng, J; Jiang, H; Liang, M; Lu, D; Pan, Y; Wang, F; Yan, X; Yang, D; Yang, L; Zhao, J | 1 |
| Bahnson, BJ; Cerasoli, DM; Kirby, SD; Norris, JR; Richard Smith, J | 1 |
| Ajami, D; Amitai, G; Berend, S; Dale, T; Duggan, BM; Garcia, E; Green, C; Kovarik, Z; Radić, B; Radić, Z; Rebek, J; Taylor, P; Zhang, L | 1 |
| Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
| Jiang, X; Lees, J; Mao, L; Radic, Z; Rosenberg, YJ; Taylor, P; Zhang, L | 1 |
| Box, K; Ceckova, M; Dolezal, R; Gorecki, L; Hepnarova, V; Hrabinova, M; Jankockova, J; Jost, P; Jun, D; Kobrlova, T; Korabecny, J; Kuca, K; Malinak, D; Musilek, K; Nepovimova, E; Nguyen, TD; Outhwaite, B; Pavek, P; Pham, NL; Psotka, M; Sorf, A; Soukup, O | 1 |
| Balasubramanian, N; Chao, CK; Gerdes, JM; Thompson, CM | 1 |
| Baker, CA; Bigley, AN; Boeri, MV; Cadieux, CL; Cerasoli, DM; Chen, Y; Dao, TL; DeBus, SJ; Hung, HC; Jain, P; Jiang, S; Kasten, SA; Li, W; Liu, EJ; Ma, J; Otto, TC; Raushel, FM; Sun, F; Tsao, C; Yuan, Z; Zhang, P | 1 |
| Katalinić, M; Kovarik, Z; Primožič, I; Radman Kastelic, A; Šinko, G; Zandona, A | 1 |
| Bernal, K; Brazzolotto, X; Bzdrenga, J; Chantegreil, F; Nachon, F; Trenet, E | 1 |
Other Studies
29 other study(ies) available for paraoxon and sarin
| Article | Year |
|---|---|
The effect of locally applied cholinesterase inhibitors and oximes on the acetylcholinesterase activity in different parts of the guinea-pig eye.
Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Eye; Guinea Pigs; Isoflurophate; Obidoxime Chloride; Oculomotor Muscles; Oximes; Paraoxon; Sarin | 1976 |
The specificity of carboxylesterase protection against the toxicity of organophosphorus compounds.
Topics: Acetylcholinesterase; Animals; Brain; Carboxylic Ester Hydrolases; In Vitro Techniques; Kinetics; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman; Substrate Specificity | 1992 |
Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases.
Topics: Animals; Cholinesterase Inhibitors; Dioxolanes; Dose-Response Relationship, Drug; Echothiophate Iodide; Insecticides; Male; Myocardium; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sarin; Soman; Tritium | 1990 |
Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity.
Topics: Acetylcholinesterase; Animals; Brain; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Isoflurophate; Male; Microwaves; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman | 1986 |
Phosphotriesterase--a promising candidate for use in detoxification of organophosphates.
Topics: Adult; Animals; Aryldialkylphosphatase; Brain; Cholinesterase Reactivators; Cholinesterases; Esterases; Female; Humans; Inactivation, Metabolic; Male; Mice; Mice, Inbred Strains; Middle Aged; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Sarin; Soman | 1994 |
Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni).
Topics: Animals; Baculoviridae; Butyrylcholinesterase; Cells, Cultured; Cholinesterase Inhibitors; COS Cells; Glycosylation; Humans; Hydrolysis; Larva; Lepidoptera; Organophosphates; Organophosphorus Compounds; Paraoxon; Protein Engineering; Recombinant Proteins; Sarin; Soman | 2000 |
Mobility of the active site bound paraoxon and sarin in zinc-phosphotriesterase by molecular dynamics simulation and quantum chemical calculation.
Topics: Aryldialkylphosphatase; Binding Sites; Crystallography, X-Ray; Esterases; Paraoxon; Sarin | 2001 |
Sarin and paraoxon antagonism in different.
Topics: Atropine; Autonomic Agents; Bis-Trimethylammonium Compounds; Cholinesterase Inhibitors; Humans; Paraoxon; Parathion; Phosphates; Sarin | 1957 |
Influence of physical activity on the toxicity of aerosols and vapors; inhalation toxicity of paraoxon and sarin in rats.
Topics: Administration, Inhalation; Aerosols; Animals; Autonomic Agents; Cholinesterase Inhibitors; Exercise; Motor Activity; Organophosphate Poisoning; Paraoxon; Parathion; Phosphates; Rats; Sarin | 1958 |
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors | 2006 |
Overcoming inhibitions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors | 2006 |
Fast, sensitive and cost-effective detection of nerve agents in the gas phase using a portable instrument and an electrochemical biosensor.
Topics: Biosensing Techniques; Butyrylcholinesterase; Chemical Warfare Agents; Electrochemistry; Electrodes; Environmental Monitoring; Ferrocyanides; Gases; Organothiophosphorus Compounds; Paraoxon; Sarin; Sensitivity and Specificity; Terrorism; Time Factors | 2007 |
Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Muscles; Obidoxime Chloride; Paraoxon; Perfusion; Sarin | 2008 |
Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetylcholinesterase; Animals; Brain; Cattle; Chemical Warfare Agents; Crystallography, X-Ray; Dealkylation; Humans; Insecticides; Paraoxon; Sarin; Soman; Synapses | 2009 |
Comparison of the oxime-induced reactivation of rhesus monkey, swine and guinea pig erythrocyte acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Erythrocytes; Guinea Pigs; Kinetics; Macaca mulatta; Male; Oximes; Paraoxon; Perfusion; Sarin; Sus scrofa | 2009 |
Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; Erythrocytes; Female; Guinea Pigs; Macaca mulatta; Male; Muscle, Skeletal; Oximes; Paraoxon; Sarin; Swine | 2010 |
Colorimetric dipstick for assay of organophosphate pesticides and nerve agents represented by paraoxon, sarin and VX.
Topics: Chemical Warfare Agents; Color; Colorimetry; Limit of Detection; Organophosphates; Organothiophosphorus Compounds; Paraoxon; Pesticides; Sarin | 2010 |
Effect of different buffers on kinetic properties of human acetylcholinesterase and the interaction with organophosphates and oximes.
Topics: Acetylcholinesterase; Buffers; Cholinesterase Inhibitors; Drug Interactions; Erythrocytes; Humans; Kinetics; Organophosphates; Oximes; Paraoxon; Sarin; Soman | 2011 |
Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates.
Topics: Acetamides; Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Evaluation, Preclinical; GPI-Linked Proteins; Humans; Kinetics; Models, Molecular; Organophosphates; Organophosphorus Compounds; Oximes; Paraoxon; Sarin | 2013 |
Fe3O4 magnetic nanoparticle peroxidase mimetic-based colorimetric assay for the rapid detection of organophosphorus pesticide and nerve agent.
Topics: Acetylcholinesterase; Alcohol Oxidoreductases; Biomimetic Materials; Catalysis; Chemical Warfare Agents; Colorimetry; Ferrosoferric Oxide; Hydrogen Peroxide; Magnetite Nanoparticles; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidation-Reduction; Paraoxon; Pesticides; Phosphoramides; Sarin | 2013 |
Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents.
Topics: Amino Acid Substitution; Antidotes; Aryldialkylphosphatase; Catalytic Domain; Chemical Warfare Agents; Humans; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Protein Engineering; Recombinant Proteins; Sarin; Soman; Substrate Specificity | 2013 |
Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes.
Topics: Animals; Butyrylcholinesterase; Catalysis; Chemical Warfare Agents; Female; Humans; Hydrogen-Ion Concentration; Inactivation, Metabolic; Kinetics; Mice; Mice, Inbred Strains; Organophosphates; Oximes; Paraoxon; Sarin | 2013 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor.
Topics: Acetamides; Acetylcholinesterase; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; Gases; Inhalation; Macaca; Models, Animal; Oximes; Paraoxon; Recombinant Proteins; Sarin | 2017 |
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
Topics: Animals; Antidotes; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Paraoxon; Rats; Sarin | 2018 |
The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; Enzyme Activation; Fluorescence; Humans; Kinetics; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Sarin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2018 |
Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents.
Topics: Administration, Intravenous; Animals; Female; Guinea Pigs; Male; Nanoparticles; Nerve Agents; Paraoxon; Protective Agents; Rats, Sprague-Dawley; Sarin; Survival Analysis; Time Factors; Tissue Distribution | 2019 |
Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers.
Topics: Acetylcholinesterase; Antidotes; Butyrylcholinesterase; Chemical Warfare Agents; Humans; Models, Molecular; Molecular Docking Simulation; Organophosphorus Compounds; Oximes; Paraoxon; Quinuclidines; Sarin; Structure-Activity Relationship | 2020 |
A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study.
Topics: Amino Acids; Crystallography, X-Ray; Esterases; Kinetics; Nerve Agents; Organophosphates; Organophosphorus Compounds; Paraoxon; Planctomycetales; Planctomycetes; Sarin | 2021 |