paclitaxel and taxane
paclitaxel has been researched along with taxane in 220 studies
Research
Studies (220)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 21 (9.55) | 18.2507 |
| 2000's | 79 (35.91) | 29.6817 |
| 2010's | 74 (33.64) | 24.3611 |
| 2020's | 46 (20.91) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Alvarez, C; Baxley, R; Davies, RM; Hanuman, JB; Juchum, J; Rao, KV; Stoy, M | 1 |
| Alvarado, B; Bignami, GS; Byrnes, JB; Grothaus, PG; Harada, KE; McGuire, MT; O'Malley, S; Raybould, TJ; Waller, DF | 1 |
| Kelsey, RG; Sabin, TE; Vance, NC | 1 |
| Shuler, ML | 1 |
| Arbuck, SG; McGuire, WP; Trimble, EL | 1 |
| Diehl, V; Steinmetz, T | 1 |
| Cazzulino, DL; Hanson, RL; Nanduri, VB; Patel, RN; Szarka, LJ; Wasylyk, JM | 1 |
| Stierle, A; Stierle, D; Strobel, G | 1 |
| Capri, G; Fulfaro, F; Gianni, L; Tarenzi, E | 1 |
| Fojo, A | 1 |
| Auguste, L; Baselga, J; Currie, V; Edelman, B; Fennelly, D; Francis, P; Gilewski, TA; Gollub, M; Hochhauser, D; Hudis, CA; Moynahan, ME; Norton, L; O'Donaghue, M; Salvaggio, R; Seidman, AD; Spriggs, D; Tong, W; Yao, TJ | 1 |
| Bernacki, RJ; Ojima, I; Sharma, A; Straubinger, RM | 1 |
| Chordia, MC; DiCosmo, F; Kingston, DG; Nicholov, R | 1 |
| Locke, DC; Shao, LK | 1 |
| Kerns, EH; Lee, MS; Liu, J; Mata, MJ; Volk, KJ | 1 |
| Chidester, CG; DeKoning, TF; Dobrowolski, PJ; Gebhard, I; Johnson, RA; Kelly, RC; Lopes, NM; Mattern, SJ; McGovren, JP; Nidy, EG; Pitts, TW; Qualls, SJ; Weed, SD; Wicnienski, NA | 1 |
| Loddenkemper, R; Schönfeld, N; Serke, M | 1 |
| Ohnishi, K; Ohno, R | 1 |
| Engblom, P; Grènman, S; Helenius, H; Kulmala, J; Rantanen, V | 1 |
| Bash-Babula, J; Hait, WN; Levine, AJ; Murphy, M; White, E; Yang, JM; Zhang, CC | 1 |
| Hussain, M; Jasti, BR; Parchment, RE; Vaishampayan, U | 1 |
| Ali, S; Janoff, A; Mayhew, E; Minchey, S | 1 |
| Bombardelli, E; Cantelmo, F; Distefano, M; Fattorossi, A; Ferlini, C; Gaggini, C; Gallo, D; Mancuso, S; Proietti, E; Riva, A; Scambia, G | 1 |
| Bollbuck, B; Downing, KH; Fojo, T; Giannakakou, P; Gussio, R; Nicolaou, KC; Nogales, E; Poy, G; Sackett, D; Zaharevitz, D | 1 |
| Bonoron-Adèle, S; Platel, D; Pouna, P; Robert, J | 1 |
| He, L; Horwitz, SB; Jagtap, PG; Kingston, DG; Orr, GA; Shen, HJ | 1 |
| Bouzigon, E; Briex, M; Brun, G; Brun, JL; Chêne, G; Hocke, C; Saurel, J | 1 |
| Bombardelli, E; Colombo, T; D'Incalci, M; Monestiroli, S; Morazzoni, P; Polizzi, D; Pratesi, G; Riva, A; Tortoreto, M; Zucchetti, M; Zunino, F | 1 |
| Greco, FA; Hainsworth, JD | 1 |
| Fuero-Oderda, C; Hashimoto, M; Kirikae, F; Kirikae, T; Lin, S; Nakanoc, M; Ojima, I | 1 |
| Cappuzzo, F; Green, MR; Rocha Lima, CM; Sherman, CA | 1 |
| Kaise, H; Koyanagi, Y; Kusama, M | 1 |
| Tashiro, H | 1 |
| Bombardelli, E; Distefano, M; Ferlini, C; Lin, S; Mancuso, S; Ojima, I; Pignatelli, F; Riva, A; Scambia, G | 1 |
| Cunha, KS; de Andrade, HH; Graf, U; Reguly, ML | 1 |
| Carroll, J; Gurnani, M; Hajian, G; Johnson, RC; Mathis, JM; Nielsen, LL; Shi, B; Terracina, G | 1 |
| Ahmad, I; Ali, S; Janoff, A; Masters, G; Mayhew, E; Minchey, S; Peters, A | 1 |
| Mamer, O; Sauriol, F; Sun, DA; Zamir, LO | 1 |
| Baldini, E; Bengala, C; Conte, P; Donati, S; Gennari, A; Guarneri, V; Landucci, E; Orlandini, C; Salvadori, B | 1 |
| Calafiore, AM; Gianni, L; Licata, S; Menna, P; Minotti, G; Saponiero, A; Teodori, G | 1 |
| Malkowicz, SB; Vaughn, DJ | 1 |
| Choy, H; Kim, JS; MacRae, R; Pyo, H | 1 |
| Mark, M; Meredith, DO; Reinhart, WH; Walter, R | 1 |
| Whelan, J | 1 |
| Botti, G; Capasso, I; Comella, G; Comella, P; Cortino, GR; D'Aiuto, G; Di Bonito, M; Frasci, G; Rubulotta, R; Thomas, R; Vallone, P | 1 |
| Cassidy, PB; Fitzpatrick, FA; Kelly, RC; Moos, PJ | 1 |
| Maher, JF; Villalona-Calero, MA | 1 |
| Sparano, JA | 1 |
| Bombardelli, E; Borsotti, P; Giavazzi, R; Micheletti, G; Morazzoni, P; Nicoletti, MI; Poli, M; Rieppi, M; Riva, A; Roccabianca, P; Rossi, C; Scanziani, E; Taraboletti, G; Turatto, M | 1 |
| Hensley, ML | 1 |
| Fang, Q; Hu, S; Sun, DA; Tian, X | 1 |
| Ghosh, B; Jha, S; Jha, TB; Mukherjee, S | 1 |
| Chiba, J; Iimura, S; Ishiyama, T; Soga, T; Terasawa, H; Uoto, K; Yoshino, T | 1 |
| Bleickardt, E; Kwong, MS; Murren, JR | 1 |
| Li, Y; McClay, EF | 1 |
| Aglione, S; Bajetta, E; Bernard-Marty, C; Buzzoni, R; Del Vecchio, M; Khayat, D; Nova, P; Rixe, O; Taillibert, S; Vitali, M | 1 |
| Geney, R; Li, D; Ojima, I; Ungureanu, lM | 1 |
| Di Leo, A | 1 |
| Davidson, NE | 1 |
| Banskota, AH; Kadota, S; Kouda, K; Nguyen, NT; Tezuka, Y; Usia, T | 1 |
| Mamer, O; Sauriol, F; Shi, QW; Zamir, LO | 1 |
| Bolduc, J; Carazzato, D; Jean, C; Rocheleau, MJ | 1 |
| Agrawal, NR; Ganapathi, R; Mekhail, T | 1 |
| Markman, M | 1 |
| Gallucci, JC; Hofferberth, JE; Lo, HY; Paquette, LA | 1 |
| Lo, HY; Paquette, LA | 1 |
| Dolfinger, R; Locke, DC | 1 |
| Fountzilas, G; Gogas, H | 1 |
| Ilersich, AL; Verma, S | 1 |
| Cazemier, G; de Jong, GJ; Diallo, B; Haasnoot, W; Jaziri, M; Papadoyannis, IN; Schilt, R; Theodoridis, G | 1 |
| Howarth, J; Kenny, P; McDonnell, S; O'Connor, A | 1 |
| Bear, HD; Goble, S | 1 |
| Dai, J; Guo, D; Guo, H; Hu, Q; Ye, M; Zhang, D; Zheng, J; Zhu, W | 1 |
| Capri, G; Cresta, S; Gianni, L; Grasselli, G; Minotti, G; Perotti, A | 1 |
| Cella, D; Hudgens, S; Peterman, A; Socinski, MA; Webster, K | 1 |
| Donoghue, E; Ghersi, D; Simes, J; Wilcken, N | 1 |
| Estévez, LG; Gradishar, WJ | 1 |
| Fossella, FV; Glisson, BS; Khuri, FR; Kies, MS; Kim, ES; Munden, RF; Papadimitrakopoulou, V; Pisters, KM; Rogatko, A; Statkevich, P; Summey, C; Tighiouart, M; Zaknoen, S | 1 |
| Furmanowa, M; Syklowska-Baranek, K | 1 |
| Yu, LJ; Zhao, CF | 1 |
| Colomer, R | 1 |
| Barlesi, F; Daurès, JP; Pujol, JL | 1 |
| Tominaga, T | 1 |
| Antoniou, D; Chaimala, D; Chondrou, E; Dariotaki, F; Karydis, I; Papageorgiou, C; Pavlakou, G; Stathopoulos, GP; Veslemes, M | 1 |
| Desai, N; Figg, WD; Kerbel, RS; Lee, C; Man, S; Ng, SS; Shaked, Y; Soon-Shiong, P; Sparreboom, A | 1 |
| Bekele, BN; Chen, I; Daliani, DD; Dieringer, PY; Logothetis, CJ; Mathew, P; Pagliaro, LC; Zhou, X | 1 |
| Frense, D | 1 |
| Anderson, K; Andre, F; Buchholz, TA; Buzdar, AU; Frye, D; Gonzalez-Angulo, AM; Hess, KR; Hortobagyi, GN; Kau, SW; Kuerer, HM; Mazouni, C; Pusztai, L; Symmans, WF | 1 |
| Kanamori, T; Kawashima, T; Murakami, H; Nakamura, Y | 1 |
| Amare, M; Asmar, L; Blum, JL; Dees, EC; Gill, DP; Ilegbodu, D; McMahon, RT; O'Shaughnessy, JA; Vukelja, SJ | 1 |
| Altieri, D; Fuks, Z; Kolesnick, R | 1 |
| Cannon, M; Cmelak, AJ; Forastiere, AA; Gillison, M; Goldwasser, MA; Li, S; Murphy, B; Pinto, H; Rosenthal, DI | 1 |
| Ge, GB; He, YQ; Li, W; Liu, XB; Liu, Y; Sun, J; Wang, LM; Wang, ZT; Xiao, HB; Yang, L; Zhang, JW; Zhang, YY | 1 |
| Chen, X; Fang, W; Li, H; Liu, H; Wang, H; Zhang, Y; Zuo, M | 1 |
| Ondari, ME; Walker, KD | 1 |
| Bonfill, M; Cusidó, RM; Expósito, O; Jané, A; Moyano, E; Onrubia, M; Palazón, J; Piñol, MT | 1 |
| Erez, R; Miller, K; Satchi-Fainaro, R; Segal, E; Shabat, D | 1 |
| Mengistu, YA; Nawarathne, IN; Nevarez, DM; Walker, KD | 1 |
| Auer, G; Brenton, JD; Chen, JG; Downward, J; East, P; Eklund, AC; Endesfelder, D; Habermann, JK; Hardcastle, T; Howell, M; Kim, SN; Kschischo, M; Lee, A; Li, Q; Ng, C; Nicke, B; Ried, T; Roy, R; Schuett, M; Swanton, C; Szallasi, Z; Wylie, P | 1 |
| Chung, CH; Cmelak, AJ; Diaz, R; Gilbert, J; Jaboin, JJ; Koehler, E; Morales-Paliza, M; Murphy, BA; Murphy, PB; Phillips, JG; Shyr, Y; Stinson, S; Yarbrough, WG | 1 |
| Ge, GB; Liu, HX; Liu, Y; Sun, J; Wang, LM; Yang, L; Zhang, JW; Zhang, YY | 1 |
| Geballe, MT; Prussia, AJ; Snyder, JP; Yang, Y | 1 |
| Bekele, NB; Carter, CM; Mathew, P; Pagliaro, L; Tannir, N; Tu, SM | 1 |
| Clamp, AR; Evans, S; Griffiths, RW; Hasan, J; Jayson, GC; Kumaran, GC; Mitchell, CL; Welch, RS; Zee, YK | 1 |
| DI, GH; Hu, XC; Li, JJ; Liu, GY; Lu, JS; Shao, ZM; Wang, Y; Wang, ZH; Wu, J; Yang, WT | 1 |
| Bebek, G; Budd, GT; De, S; Downs-Kelly, E; Eng, C; Orloff, MS; Stark, GR; Tan, MH; Wesolowski, R | 1 |
| Plummer, RS; Shea, CR | 1 |
| Eastwood, A; Epstein, D; Fox, D; Rodgers, M; Soares, M; Yang, H | 1 |
| Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J | 1 |
| Rzymowska, J; Ziaja-Sołtys, M | 1 |
| Beraldi, E; Gleave, ME; Kumano, M; Naito, S; Nelson, CC; Shiota, M; Sorensen, PH; Zoubeidi, A | 1 |
| Kolewe, ME; Normanly, J; Patil, RA; Roberts, SC; Walker, EL | 1 |
| Hidaka, M; Hirose, K; Horiguchi, T; Kiyota, H; Koga, T; Shi, QW; Uchida, T | 1 |
| Birrer, M; Duska, L; Ferriss, JS; Kim, Y; Lee, JK; Levine, DA; Moskaluk, C; Theodorescu, D | 1 |
| Bouchardy, C; Dehler, S; Ess, S; Frick, H; Joerger, M; Konzelmann, I; Savidan, A; Thürlimann, B | 1 |
| Chen, CM; Liu, GY; Shao, ZM; Shen, ZZ; Wu, J; Yu, KD; Zhou, XY; Zhou, Y | 1 |
| Baker, M; Borkowski, R; DeSevo, C; Du, L; Gazdar, AF; Greer, R; Minna, JD; Pertsemlidis, A; Schageman, JJ; Subauste, MC; Suraokar, M; Wistuba, II; Yang, CR; Zhao, Z | 1 |
| Bhat, A; Cardonick, E; Gilmandyar, D; Somer, R | 1 |
| Bustam, AZ; Ng, CH; Phua, CE; Saad, M; Taib, NA; Teh, YC; Yip, CH; Yusof, MM | 1 |
| Chen, X; Fang, W; Jin, J; Lang, L; Li, Y; Zhou, Q; Zhu, Z | 1 |
| Cen, P; Du, XL; Giordano, SH; Lairson, DR; Parikh, RC | 1 |
| Hertz, DL; Krens, SD; McLeod, HL | 1 |
| Cho, YJ; Hwang, YS; Jeong, YY; Kim, HC; Kim, IS; Kim, MJ; Kim, SH; Lee, GW; Lee, JD; Lee, S; Ling, H; Oh, SY | 1 |
| Dong, W; Feng, L; Giordano, SH; Hortobagyi, GN; Jiralerspong, S; Kim, ES | 1 |
| Kudlowitz, D; Muggia, F | 1 |
| Cai, P; Fang, WS; Lu, P; Sharom, FJ | 1 |
| Hirsh, V; Hon, JK; Okamoto, I; Orsini, J; Page, RD; Renschler, MF; Sakai, H; Socinski, MA; Zhang, H | 1 |
| Baek, KH; Hasan, MM; Jeon, JH; Kim, HS; Kim, SH; Moon, B; Shim, SH; Song, JY | 1 |
| Akslen, LA; Birkeland, E; Bredholt, T; Halle, MK; Krakstad, C; Salvesen, HB; Tangen, IL; Trovik, J; Werner, HM; Wik, E | 1 |
| Abraham, JE; Bowden, SJ; Burns, R; Caldas, C; Dorling, L; Dunn, JA; Earl, HM; Guo, Q; Hardy, R; Hiller, L; Ingle, S; Jones, L; Pharoah, PP; Poole, CJ; Tyrer, J; Vallier, AL | 1 |
| Imada, K; Inokuchi, J; Itsumi, M; Kashiwagi, E; Naito, S; Shiota, M; Takeuchi, A; Tatsugami, K; Uchiumi, T; Yokomizo, A | 1 |
| de Bruijn, P; Ghobadi Moghaddam-Helmantel, IM; Gibson, AA; Gui, C; Hagenbuch, B; Hu, S; Mathijssen, RH; Nieuweboer, AJ; Sparreboom, A | 1 |
| Fujimoto, M; Fujisawa, Y; Kadono, T; Miyagawa, T; Nakamura, Y; Yoshino, K | 1 |
| Boggs, DH; Burrows, W; Hanna, A; Horiba, N; Morris, CG; Suntharalingam, M; Tarabolous, C | 1 |
| Chen, QH; Kingston, DG | 1 |
| Burt, HM; Jackson, JK; Letchford, K; Leung, D; Wan, CPL | 1 |
| Fridley, BL; Ghosh, TM; Gupta, P; Lamba, JK; Mehta, G; Yu, Q | 1 |
| Colbert, PL; Lee, JH; Vermeer, DW; Vermeer, PD; Wieking, BG | 1 |
| Chenchik, A; Kandel, ES; Makhanov, M; Matveev, V; Zynda, ER | 1 |
| Aliño, SF; Bosó, V; de la Cueva, H; Herrero, MJ; Marqués, MR; Megias, JE; Montalar, J; Palomar, L; Poveda, JL; Rojas, L; Santaballa, A | 1 |
| Altabella, T; Cusido, RM; Goossens, A; Moyano, E; Notredame, C; Onrubia, M; Osuna, L; Palazon, J; Ramírez-Estrada, K; Vanden Bossche, R | 1 |
| Alqahtani, S; Ambudkar, SV; Ashby, CR; Chen, ZS; Kaddoumi, A; Kathawala, RJ; Shukla, S; Wang, YJ; Zhang, YK | 1 |
| Jiang, J; Liu, H; Liu, Z; Lv, J; Wang, L; Wang, Q; Wen, X; Zheng, X; Zhou, X | 1 |
| Bonfill, M; Cusido, RM; Moyano, E; Osuna, L; Palazon, J; Ramirez-Estrada, K; Tapia, N | 1 |
| Logie, J; McLaughlin, CK; Shoichet, MS; Tam, RY | 1 |
| Alba, E; Álvarez, I; Andrés, R; Aramendía, JM; Barnadas, A; Batista, N; Calvo, L; Ciruelos, E; Cortés, J; de Dueñas, EM; de la Haba, J; de la Peña, FA; Galve, E; García-Palomo, A; García-Sáenz, JÁ; González-Martín, A; Llombart, A; Lluch, A; López, R; López-Vivanco, G; Martín, M; Martínez-Jáñez, N; Plazaola, A; Rodríguez-Lescure, Á; Ruiz, M; Sánchez-Rovira, P; Santaballa, A; Seguí, MÁ; Tusquets, I; Zamora, P | 1 |
| Anthes, LE; Corkery, DP; Dellaire, G; Holly, A; Lahsaee, S | 1 |
| Hasegawa, J; Hirota, M; Ikenaga, M; Kameda, C; Kawabata, R; Kawase, T; Kimura, Y; Koga, C; Matsumura, T; Murakami, M; Noura, S; Shimizu, J; Yoshikawa, M | 1 |
| Pugliano, L; Ryan, C; Tsoi, D; White, M; Woodward, N | 1 |
| Chen, Z; Du, F; He, D; Jin, J; Li, H; Lu, H; Ma, X; Pan, Q; Tang, C; Wang, Y; Yao, X; Zang, X; Zhang, P | 1 |
| Ardizzoni, A; Barbera, S; Belani, C; Belvedere, O; Boni, L; Brunsvig, PF; Buffoni, L; Caroti, C; Ceschia, T; Cortinovis, D; D'Alessandro, V; de Marinis, F; Di Maio, M; Favaretto, A; Grimaldi, A; Grossi, F; Huber, RM; Loreggian, L; Morrica, B; Navarria, P; Parisi, S; Ricardi, U; Scagliotti, GV; Scolaro, T; Tiseo, M; Tixi, L | 1 |
| Jodrell, DI; Koh, SB; Lin, Y; Lyons, SK; Mascalchi, P; Richards, FM; Rodriguez, E | 1 |
| Díaz, JF; Downing, KH; Hejab, NMA; Howes, S; Kellogg, EH; Miller, JH; Nogales, E; Northcote, P | 1 |
| Faria, C; Force, RW; Margunato-Debay, S; Patel, MB; Peterson, T; Pugmire, BA; Weiss, J | 1 |
| Chang, JT; Hui, RL; Millares, M; Rashid, N; Schottinger, JE; Spence, MM | 1 |
| Awale, S; Dang, PH; Duong, TTT; Nguyen, HX; Nguyen, MTT; Nguyen, NT; Nguyen, PT; Phan, NHT; Tran, TKT; Vu, TKT; Vuong, HC | 1 |
| de Boer, M; Dercksen, MW; Joore, MA; Lobbezoo, DJA; Peters, FPJ; Peters, NAJB; Ramaekers, BLT; Smilde, TJ; Tjan-Heijnen, VCG; van de Wouw, AJ; van den Berkmortel, F; van Kampen, RJW; van Riel, JMG | 1 |
| Bharadwaj, G; Lam, KS; Li, X; Li, Y; Macarenco, AC; Narayanan, A; Nhan, V; Shi, Y; Vieira, LS; Xiao, W; Yang, D; Yang, S | 1 |
| Picard, M | 1 |
| Bagdas, D; Bigbee, JW; Chen, ZJ; Damaj, MI; Del Fabbro, E; Fang, X; Gewirtz, DA; Kyte, SL; Lichtman, AH; Meade, JA; Schurman, LD; Toma, W | 1 |
| Brunner, AL; Cain, J; Cancilla, B; Cattaruzza, F; Evans, JW; Fischer, MM; Hoey, T; Hussein, R; Kapoun, A; Murriel, C; O'Young, G; Wang, M; Yen, WC; Yeung, VP | 1 |
| Hu, Q; Xie, B; Xu, Z; Zhang, W; Zhang, X; Zheng, J; Zhou, J | 1 |
| Abu-Khalaf, M; Brandt, DS; Burrello, T; Chagpar, A; DiGiovanna, MP; Foldi, J; Frederick, C; Hatzis, C; Hofstatter, EW; Horowitz, N; Killelea, B; Lannin, D; Mougalian, S; Pusztai, L; Rispoli, L; Sabbath, K; Sanft, T; Silber, A | 1 |
| Laoitthi, P; Parinyanitikul, N; Poovorawan, N; Rattananupong, T; Sithidetphaiboon, P; Sriuranpong, V; Tanpipattanakul, W; Thanasanvimon, S | 1 |
| Bonfill, M; Cusidó, RM; Moyano, E; Palazón, J; Sanchez-Muñoz, R | 1 |
| Georgalas, I; Kanakis, M; Makatsoris, T; Pharmakakis, N | 1 |
| Blohmer, JU; Braun, S; Denkert, C; Elkin, EP; Fasching, PA; Gerber, B; Hahnen, E; Hartman, AR; Jackisch, C; Klare, P; Kümmel, S; Lederer, B; Loibl, S; Nekljudova, V; Paepke, S; Penn, S; Reid, J; Rezai, M; Rhiem, K; Salat, CT; Schem, C; Schmutzler, R; Schneeweiss, A; Timms, KM; Untch, M; von Minckwitz, G; Weber, KE; Zahm, DM | 1 |
| Duran, GE; Sikic, BI | 1 |
| Altman, RB; Cormier, O; Katzenellenbogen, JA; Liu, T; Lo, YC; Nettles, KW; Stearns, T | 1 |
| Aoki, D; Arai, M; Matoda, M; Michimae, H; Mizuno, M; Nakai, H; Nakanishi, T; Nomura, H; Saito, M; Saito, T; Sasagawa, M; Sugiyama, T; Takahashi, F; Tokunaga, H; Ushijima, K; Watanabe, Y; Yaegashi, N | 1 |
| Chon, HJ; Chung, HC; Jung, M; Kang, B; Kim, C; Kim, HS; Kim, JH; Nam, CM; Rha, SY | 1 |
| Dvorak, P; Ehrlichova, M; Flasarova, D; Hlavac, V; Kocik, M; Mohelnikova-Duchonova, B; Ojima, I; Oliverius, M; Soucek, P; Strouhal, O | 1 |
| Damizia, M; Di Francesco, L; Lavia, P; Le Pera, L; Rovella, P; Schininà, ME; Staid, DS; Verrico, A | 1 |
| Brunken, L; Hassan, N; Jackson, J; Mellor, C; Mitchell, E; Ng'andu, K; O'Brien, A; Paus, R; Purba, TS; Shahmalak, A; Smart, E | 1 |
| Balolong-Garcia, JC; Cruz-Ordinario, MVB; Pandy, JGP; Que, FVF | 1 |
| Nawarathne, IN; Sullivan, SA; Walker, KD | 1 |
| Deng, M; Li, Z; Liu, B; Lv, Q; Xin, X; Zhang, Y; Zhang, Z; Zhao, Z | 1 |
| Calixto, JB; Campos, MM; da Costa, R; Fernandes, ES; Maia, JRLCB; Passos, GF; Quintão, NLM | 1 |
| Brás, R; Caiado, J; Castells, M; Costa, L; Paulino, M | 1 |
| Hara, F; Iwamoto, T; Mukai, H; Ohashi, Y; Uemura, Y; Watanabe, T | 1 |
| d'Espaux, L; Dennis, JA; Keasling, JD; Li, RA; Malcı, K; Martinez, JL; Nowrouzi, B; Rios-Solis, L; Semião, AJC; Wallace, S; Walls, LE; Wong, J | 1 |
| Beerepoot, LV; Creemers, GJ; de Vos-Geelen, J; Dijksterhuis, WPM; Haj Mohammad, N; Lemmens, VEPP; Pape, M; Slingerland, M; van Laarhoven, HWM; van Oijen, MGH; van Voorthuizen, T; Verhoeven, RHA | 1 |
| Chang, PM; Fang, CY; Hsiao, M; Hsieh, HL; Jan, YH; Lai, TC; Liu, CY; Yang, YF | 1 |
| Joerger, M; Kloft, C; Muth, M; Ojara, FW | 1 |
| Fischbach, C; Kalish, M; Pabst, L; Petit, T; Pflumio, C; Pivot, X; Velten, M | 1 |
| Li, L; Shu, X; Wang, N; Wang, T; Wang, Z; Zhang, F; Zhuang, W | 1 |
| Alasino, RV; Beltramo, DM; Bierbrauer, KL; Comini, LR; Leonhard, V | 1 |
| Abdeddaim, C; Clatot, F; Even, C; Guiard, E; Johnson, A; Perréard, M; Rambeau, A; Vauléon, E | 1 |
| Cicka, D; Doyle, S; Du, Y; Fan, D; Fu, H; Ivanov, AA; Mo, X; Niu, Q; Qian, K; Shu, C; Wuhafu, A; Zheng, X | 1 |
| Al-Wahsh, H; Ferraiuolo, RM; Fifield, BA; Gupta, R; Hamm, C; Hussein, A; Kay, A; Kulkarni, S; Mailloux, E; Mathews, J; Porter, LA | 1 |
| Borazanci, E; Custodio, JM; Fleming, GF; Grauer, A; Greenstein, AE; Munster, PN; Pashova, HI; Sachdev, JC; Sharma, MR; Shepherd, SP; Tudor, IC | 1 |
| Mellerick, A; Nicolae, R; Siderov, J; Uccellini, A; Wong, V; Yeo, B | 1 |
| Antonio-Aguirre, B; Armenta-Quiroga, AS; Catalán, R; Espinosa-Fernandez, JR; Estrada-Mena, FJ; Freyria, A; Guijosa, A; Ortega-Treviño, MF; Perez-Ortiz, AC; Villarreal-Garza, C | 1 |
| Bamneshin, M; Cusido, RM; Mirjalili, MH; Naghavi, MR; Palazón, J | 1 |
| Etminan, M; Maberley, D; Mikelberg, F; Sodhi, M; Yeung, SN | 1 |
| Drier, SW; Ekwueme, DU; Fairley, TL; Gogate, A; Reeder-Hayes, KE; Rocque, GB; Rotter, J; Trogdon, JG; Wheeler, SB | 1 |
| Lungang, L; Nowrouzi, B; Rios-Solis, L | 1 |
| Dilawari, A; Graham, D; Isaacs, C; Kurian, S; Lynce, F; Mainor, C; McNamara, D; Mohebtash, M; Ottaviano, Y; Pohlmann, PR; Rao, S; Swain, SM; Swanson, N; Tan, M; Warren, R; Wu, T | 1 |
| Accetta, C; Carbognin, L; D'Angelo, T; Di Giorgio, D; Di Leone, A; Fabi, A; Franceschini, G; Fuso, P; Garganese, G; Giannarelli, D; Magno, S; Masetti, R; Muratore, M; Paris, I; Pavese, F; Sanchez, AM; Scambia, G; Terribile, DA; Tiberi, G | 1 |
| Cao, M; Li, H; Lv, Z; Ma, F; Mo, H; Pan, B; Song, G; Sun, X; Teng, Y; Xu, B; Yan, X; Zhai, J; Zhao, F; Zhao, J | 1 |
| Amato, O; Bria, E; Canino, F; Carbognin, L; Cumerlato, E; Dieci, MV; Fassan, M; Garufi, G; Genovesi, E; Giannarelli, D; Giorgi, CA; Griguolo, G; Guarneri, V; Lo Mele, M; Massa, D; Michieletto, S; Miglietta, F; Piacentini, F; Saibene, T; Tornincasa, A; Trudu, L; Zarrilli, G | 1 |
| Cao, M; Li, H; Lv, Z; Ma, F; Mo, H; Pan, B; Sun, X; Xu, B; Zhai, J; Zhao, F; Zhao, J | 1 |
| Feng, R; Li, L; Yin, J; Zhang, J; Zhang, X; Zheng, Y | 1 |
| Altmann, KH; Bargsten, K; Díaz, JF; Estevez-Gallego, J; Fang, WS; Gago, F; Gaillard, N; Josa-Prado, F; Kamimura, S; Li, S; Lucena-Agell, D; Ma, Y; Mühlethaler, T; Oliva, MA; Prota, AE; Steinmetz, MO | 1 |
| Asano, Y; Fujimura, T; Fujisawa, Y; Hashimoto, A; Ishizuki, S; Ito, T; Kambayashi, Y; Kato, H; Maekawa, T; Matsushita, S; Segawa, K; Yamamoto, J; Yoshino, K | 1 |
| Cardoso, AM; Coelho, RS; Maia, CJ; Nascimento, D; Passarinha, LA; Rocha, SM; Socorro, S | 1 |
| Costa, J; Jabaley, T; Lynch, DM; Mazzola, E; Menon, S | 1 |
| Cathcart-Rake, EJ; Childs, DS; Kochan, DC; Novotny, PJ; Orme, JJ; Ruddy, KJ; Tevaarwerk, AJ | 1 |
| Cantor, E; Dang, C; Gardner, L; Jiang, G; Ly, RC; Miller, KD; Northfelt, D; Osei, W; Philips, S; Schneider, BP; Shen, F; Skaar, T; Sledge, GW; Wu, X; Xue, G | 1 |
| Kubota, K; Kunitoh, H; Maruyama, R; Matsuda, A; Ohira, T; Okamoto, H; Seto, T; Tsuboi, M; Yamaoka, K | 1 |
| Dang, CT; Du Toit, Y; Hurvitz, SA; Knott, A; Polito, L; Restuccia, E; Sanglier, T; Shim, J; Swain, SM | 1 |
| Contorno, T; McGwin, G; Owsley, C; Vicinanzo, MG | 1 |
| Aoyama, S; Iwamoto, H; Izumi, K; Kadomoto, S; Kadono, Y; Kamijima, T; Kano, H; Mizokami, A; Naito, R; Nakagawa, R; Nakagawa-Goto, K; Nakata, H; Saito, Y; Shimada, T; Toriumi, R; Yaegashi, H | 1 |
| Baek, JM; Jeon, YW; Kang, YJ; Kim, D; Kim, YS; Oh, SJ; Rhu, J; Yang, YJ; Yi, JP; Yoon, CI | 1 |
| Bhangale, T; Chandler, GS; Crow, M; Hackos, DH; Jung, M; Kaminker, JS; Khan, Z; Maiya, V; McCarthy, MI; Mohindra, R | 1 |
| Egawa, G; Endo, Y; Fujii, H; Ishikawa, M; Kabashima, K; Yonekura, S | 1 |
| Chan, PY; Diaz, JF; Essif, JN; Fang, WS; Gago, F; Goossens, K; Hortigüela, R; Josa-Prado, F; Li, S; Liu, S; Lucena-Agell, D; Ma, Y; Matesanz, R; Risinger, A; Wang, H; Wang, Y | 1 |
| Chen, H; Deng, Y; Zhang, M | 1 |
| Chen, C; Li, CX; Xie, WL; Xu, JH; Zhang, MF | 1 |
| Ai, X; Hao, X; Lei, S; Li, W; Wang, Y; Xu, H; Yang, G; Yang, Y; Zhang, S | 1 |
Reviews
46 review(s) available for paclitaxel and taxane
| Article | Year |
|---|---|
Bioreactor engineering as an enabling technology to tap biodiversity. The case of taxol.
Topics: Biological Products; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cells, Cultured; Conservation of Natural Resources; Culture Techniques; Microtubules; Paclitaxel; Plant Cells; Plants; Taxoids; Trees | 1994 |
Options for primary chemotherapy of epithelial ovarian cancer: taxanes.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cisplatin; Docetaxel; Female; Humans; Ovarian Neoplasms; Paclitaxel; Remission Induction; Taxoids | 1994 |
The role of taxanes in the treatment of breast cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Clinical Trials, Phase II as Topic; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Humans; Paclitaxel; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Taxoids | 1996 |
Taxanes.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Clinical Trials as Topic; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Humans; Paclitaxel; Taxoids | 1996 |
[New antitumor drugs for non-Hodgkin's lymphoma].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Clinical Trials as Topic; Cyclophosphamide; Docetaxel; Doxorubicin; Drug Administration Schedule; Humans; Lymphoma, Non-Hodgkin; Paclitaxel; Prednisone; Rituximab; Taxoids; Vincristine | 1998 |
Taxanes: an overview of the pharmacokinetics and pharmacodynamics.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Docetaxel; Drug Interactions; Humans; Male; Mitosis; Molecular Structure; Paclitaxel; Prostatic Neoplasms; Taxoids | 1999 |
Advances in treatment of inoperable NSCLC: gemcitabine doublets--a promising alternative.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Deoxycytidine; Disease-Free Survival; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Gemcitabine; Humans; Lung Neoplasms; Paclitaxel; Randomized Controlled Trials as Topic; Remission Induction; Taxoids; Vinblastine; Vinorelbine | 2000 |
[Neoadjuvant chemotherapy for breast-conservative surgery].
Topics: Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Female; Humans; Paclitaxel; Premedication; Taxoids; Treatment Outcome | 2000 |
[Standard chemotherapy for metastatic breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Paclitaxel; Practice Guidelines as Topic; Prognosis; Taxoids | 2000 |
Epirubicin/taxane combinations in breast cancer: experience from several Italian trials.
Topics: Breast Neoplasms; Bridged-Ring Compounds; Docetaxel; Drug Therapy, Combination; Epirubicin; Female; Humans; Italy; Meta-Analysis as Topic; Paclitaxel; Taxoids | 2001 |
Recent developments in chemotherapy for bladder cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bridged-Ring Compounds; Carboplatin; Deoxycytidine; Gemcitabine; Humans; Neoadjuvant Therapy; Paclitaxel; Taxoids; Urinary Bladder Neoplasms | 2001 |
Role of taxanes in the combined modality treatment of patients with locally advanced non-small cell lung cancer.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Docetaxel; Guidelines as Topic; Lung Neoplasms; Multicenter Studies as Topic; Neoplasm Staging; Paclitaxel; Taxoids; Treatment Outcome | 2001 |
Taxanes and capecitabine in combination: rationale and clinical results.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Deoxycytidine; Docetaxel; Drug Administration Schedule; Drug Synergism; Fluorouracil; Humans; Paclitaxel; Survival Analysis; Taxoids; Thymidine Phosphorylase; Treatment Outcome; Up-Regulation | 2002 |
Taxanes for breast cancer: an evidence-based review of randomized phase II and phase III trials.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Disease Progression; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Medicine; Female; Genes, erbB-2; Humans; Infusions, Intravenous; Neoadjuvant Therapy; Neoplasm Staging; Paclitaxel; Quality of Life; Randomized Controlled Trials as Topic; Survival Analysis; Taxoids; Treatment Outcome | 2000 |
Epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Combined Modality Therapy; Deoxycytidine; Docetaxel; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; Ifosfamide; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Platinum Compounds; Practice Guidelines as Topic; Tamoxifen; Taxoids; Topotecan; Vinblastine; Vinorelbine | 2002 |
Camptothecin and taxane regimens for small-cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Camptothecin; Carcinoma, Small Cell; Docetaxel; Humans; Irinotecan; Lung Neoplasms; Paclitaxel; Randomized Controlled Trials as Topic; Taxoids | 2002 |
Systemic chemotherapy for the treatment of metastatic melanoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carmustine; Cisplatin; Clinical Trials as Topic; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Paclitaxel; Tamoxifen; Taxoids; Temozolomide | 2002 |
Metastatic melanoma: chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Cisplatin; Clinical Trials as Topic; Cytokines; Dacarbazine; Genetic Therapy; Humans; Immunotherapy; Interferon-alpha; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Paclitaxel; Tamoxifen; Taxoids; Thalidomide | 2002 |
Overcoming multidrug resistance in taxane chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Bridged-Ring Compounds; Clinical Trials as Topic; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Models, Molecular; Paclitaxel; Taxoids | 2002 |
The European experience with docetaxel in the treatment of early-stage breast cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Europe; Female; Genes, p53; Humans; Multicenter Studies as Topic; Paclitaxel; Randomized Controlled Trials as Topic; Taxoids | 2002 |
Ongoing US cooperative group trials using taxanes in the adjuvant setting.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Multicenter Studies as Topic; Paclitaxel; Randomized Controlled Trials as Topic; Risk Factors; Taxoids; Trastuzumab; United States | 2002 |
Tubulin interacting agents: novel taxanes and epothilones.
Topics: Antineoplastic Agents; Apoptosis; Bridged-Ring Compounds; Clinical Trials as Topic; Drug Delivery Systems; Drug Resistance, Neoplasm; Epothilones; Humans; Paclitaxel; Taxoids; Tubulin | 2003 |
Managing taxane toxicities.
Topics: Antineoplastic Agents, Phytogenic; Arthralgia; Bridged-Ring Compounds; Docetaxel; Drug Hypersensitivity; Humans; Neutropenia; Paclitaxel; Peripheral Nervous System Diseases; Taxoids; Thrombocytopenia | 2003 |
The role of taxanes as a component of neoadjuvant chemotherapy for breast cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Clinical Trials as Topic; Docetaxel; Humans; Neoadjuvant Therapy; Paclitaxel; Taxoids | 2003 |
Emerging role of taxanes in adjuvant and neoadjuvant therapy for breast cancer: the potential and the questions.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Docetaxel; Female; Humans; Neoadjuvant Therapy; Paclitaxel; Taxoids | 2003 |
Cardiotoxic effects of anthracycline-taxane combinations.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Clinical Trials as Topic; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Female; Heart Diseases; Humans; Paclitaxel; Risk; Taxoids | 2003 |
Taxane containing regimens for metastatic breast cancer.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Disease Progression; Female; Humans; Paclitaxel; Randomized Controlled Trials as Topic; Tamoxifen; Taxoids | 2003 |
Evidence-based use of neoadjuvant taxane in operable and inoperable breast cancer.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Clinical Trials as Topic; Docetaxel; Female; Humans; Paclitaxel; Taxoids; Treatment Outcome | 2004 |
What is the best schedule for administration of gemcitabine-taxane?
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Deoxycytidine; Drug Administration Schedule; Drug Synergism; Female; Gemcitabine; Humans; Neoplasm Metastasis; Paclitaxel; Receptor, ErbB-2; Remission Induction; Taxoids; Trastuzumab | 2005 |
Should chemotherapy combinations for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials, Phase III as Topic; Deoxycytidine; Epirubicin; Gemcitabine; Humans; Ifosfamide; Lung Neoplasms; Paclitaxel; Randomized Controlled Trials as Topic; Survival Rate; Taxoids; Vinblastine; Vinorelbine | 2006 |
[Clinical trials of vnorelbine in breast cancer--its scientific usefulness and development history until regulatory approval].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Approval; Female; Fluorouracil; Humans; Japan; Lung Neoplasms; Male; Paclitaxel; Taxoids; Vinblastine; Vinorelbine | 2006 |
Taxanes: perspectives for biotechnological production.
Topics: Bridged-Ring Compounds; Cell Culture Techniques; Docetaxel; Molecular Structure; Paclitaxel; Taxoids; Taxus | 2007 |
Inclusion of taxanes, particularly weekly paclitaxel, in preoperative chemotherapy improves pathologic complete response rate in estrogen receptor-positive breast cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Paclitaxel; Prognosis; Receptors, Estrogen; Survival Analysis; Taxoids; Tumor Burden | 2007 |
Bevacizumab in combination with a taxane for the first-line treatment of HER2-negative metastatic breast cancer.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Breast Neoplasms; Bridged-Ring Compounds; Deoxycytidine; Disease-Free Survival; Docetaxel; Drug Therapy, Combination; Female; Gemcitabine; Humans; Neoplasm Metastasis; Paclitaxel; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Taxoids | 2011 |
Maternal and fetal outcomes of taxane chemotherapy in breast and ovarian cancer during pregnancy: case series and review of the literature.
Topics: Antineoplastic Agents; Birth Weight; Breast Neoplasms; Bridged-Ring Compounds; Cohort Studies; Docetaxel; Female; Gestational Age; Humans; Ovarian Neoplasms; Paclitaxel; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Retrospective Studies; Taxoids | 2012 |
Defining risks of taxane neuropathy: insights from randomized clinical trials.
Topics: Axons; Bridged-Ring Compounds; Docetaxel; Drug-Related Side Effects and Adverse Reactions; Humans; Nanoparticles; Neoplasms; Paclitaxel; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Taxoids | 2013 |
Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Lactones; Macrolides; Marine Biology; Microtubules; Molecular Structure; Paclitaxel; Taxoids; Tubulin | 2014 |
Nab-Paclitaxel in Metastatic Breast Cancer: Defining the Best Patient Profile.
Topics: Albumins; Animals; Breast Neoplasms; Bridged-Ring Compounds; Female; Humans; Nanoparticles; Paclitaxel; Taxoids | 2016 |
Management of patients treated with pertuzumab in the Australian clinical practice setting.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Australia; Breast Neoplasms; Bridged-Ring Compounds; Disease Management; Disease Progression; Docetaxel; Female; Humans; Neoplasm Recurrence, Local; Paclitaxel; Receptor, ErbB-2; Taxoids; Trastuzumab | 2016 |
Management of Hypersensitivity Reactions to Taxanes.
Topics: Allergens; Animals; Antineoplastic Agents; Bridged-Ring Compounds; Desensitization, Immunologic; Docetaxel; Drug Hypersensitivity; Humans; Paclitaxel; Skin Tests; Taxoids | 2017 |
Triple negative breast cancer and platinum-based systemic treatment: a meta-analysis and systematic review.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; Bridged-Ring Compounds; Carboplatin; Female; Humans; Mutation; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Progression-Free Survival; Randomized Controlled Trials as Topic; Taxoids; Triple Negative Breast Neoplasms | 2019 |
Taxane-induced neurotoxicity: Pathophysiology and therapeutic perspectives.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Docetaxel; Humans; Paclitaxel; Taxoids | 2020 |
Role of TDM-based dose adjustments for taxane anticancer drugs.
Topics: Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Docetaxel; Female; Humans; Paclitaxel; Taxoids | 2021 |
Recent Research Progress in Taxol Biosynthetic Pathway and Acylation Reactions Mediated by
Topics: Acylation; Acyltransferases; Amino Acid Sequence; Antineoplastic Agents; Biosynthetic Pathways; Bridged-Ring Compounds; Ligases; Mixed Function Oxygenases; Paclitaxel; Plant Extracts; Taxoids; Taxus; Transcriptome | 2021 |
Pharmacogenetics of taxane-induced neurotoxicity in breast cancer: Systematic review and meta-analysis.
Topics: Breast Neoplasms; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Female; Genetic Markers; Humans; Liver-Specific Organic Anion Transporter 1; Neurotoxicity Syndromes; Paclitaxel; Peripheral Nervous System Diseases; Pharmacogenetics; Polymorphism, Single Nucleotide; Taxoids | 2022 |
Long Noncoding RNAs in Taxane Resistance of Breast Cancer.
Topics: Breast Neoplasms; Female; Humans; Paclitaxel; RNA, Long Noncoding; Taxoids | 2023 |
Trials
22 trial(s) available for paclitaxel and taxane
| Article | Year |
|---|---|
Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: a phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Docetaxel; Female; Humans; Infusions, Intravenous; Middle Aged; Paclitaxel; Taxoids | 1996 |
A phase I-II study on a gemcitabine-cyclophosphamide-fluorouracil/folinic acid triplet combination in anthracycline- and taxane-refractory breast cancer patients.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Cyclophosphamide; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Gemcitabine; Humans; Leucovorin; Middle Aged; Neoplasm Metastasis; Paclitaxel; Survival Rate; Taxoids | 2002 |
Population-based pharmacoeconomic model for adopting capecitabine/docetaxel combination treatment for anthracycline-pretreated metastatic breast cancer.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Budgets; Capecitabine; Cost-Benefit Analysis; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Female; Fluorouracil; Follow-Up Studies; Humans; Neoplasm Metastasis; Ontario; Paclitaxel; Population Surveillance; Survival Analysis; Taxoids; Trastuzumab; Treatment Outcome; Vinblastine; Vinorelbine; Women's Health | 2003 |
Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma.
Topics: Adult; Aged; Alkyl and Aryl Transferases; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Drug Therapy, Combination; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Paclitaxel; Piperidines; Pyridines; Remission Induction; Survival Rate; Taxoids; Treatment Outcome | 2005 |
Thalidomide/estramustine/paclitaxel in metastatic androgen-independent prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Disease Progression; Estramustine; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Paclitaxel; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Rate; Taxoids; Thalidomide; Time Factors; Treatment Outcome | 2006 |
Inclusion of taxanes, particularly weekly paclitaxel, in preoperative chemotherapy improves pathologic complete response rate in estrogen receptor-positive breast cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Paclitaxel; Prognosis; Receptors, Estrogen; Survival Analysis; Taxoids; Tumor Burden | 2007 |
Phase II trial of capecitabine and weekly paclitaxel in patients with metastatic breast cancer previously treated with every-3-week taxane therapy.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Chemotherapy, Adjuvant; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Humans; Middle Aged; Paclitaxel; Taxoids | 2007 |
Phase II trial of chemoradiation for organ preservation in resectable stage III or IV squamous cell carcinomas of the larynx or oropharynx: results of Eastern Cooperative Oncology Group Study E2399.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Deglutition Disorders; Female; Follow-Up Studies; Humans; Laryngeal Neoplasms; Laryngectomy; Male; Middle Aged; Neoplasm Staging; Oropharyngeal Neoplasms; Paclitaxel; Pharyngectomy; Platinum; Radiotherapy, Adjuvant; Recovery of Function; Salvage Therapy; Speech Disorders; Taxoids; Treatment Outcome | 2007 |
A modular Phase I study of lenalidomide and paclitaxel in metastatic castration-resistant prostate cancer following prior taxane therapy.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Combined Modality Therapy; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Lenalidomide; Male; Middle Aged; Nausea; Neutropenia; Orchiectomy; Paclitaxel; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Analysis; Taxoids; Thalidomide; Treatment Outcome; Vomiting | 2010 |
Patient-reported neuropathy and taxane-associated symptoms in a phase 3 trial of nab-paclitaxel plus carboplatin versus solvent-based paclitaxel plus carboplatin for advanced non-small-cell lung cancer.
Topics: Adult; Aged; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Paraneoplastic Polyneuropathy; Quality of Life; Taxoids | 2014 |
Randomized phase III PITCAP trial and meta-analysis of induction chemotherapy followed by thoracic irradiation with or without concurrent taxane-based chemotherapy in locally advanced NSCLC.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Female; Humans; Induction Chemotherapy; Male; Meta-Analysis as Topic; Middle Aged; Neoplasm Staging; Paclitaxel; Survival Rate; Taxoids; Treatment Outcome | 2016 |
Real-world and trial-based cost-effectiveness analysis of bevacizumab in HER2-negative metastatic breast cancer patients: a study of the Southeast Netherlands Breast Cancer Consortium.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Bridged-Ring Compounds; Cost-Benefit Analysis; Disease Progression; Docetaxel; Female; Health Resources; Humans; Kaplan-Meier Estimate; Netherlands; Paclitaxel; Quality-Adjusted Life Years; Receptor, ErbB-2; Taxoids | 2017 |
Single-arm, neoadjuvant, phase II trial of pertuzumab and trastuzumab administered concomitantly with weekly paclitaxel followed by 5-fluoruracil, epirubicin, and cyclophosphamide (FEC) for stage I-III HER2-positive breast cancer.
Topics: Adult; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Bridged-Ring Compounds; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Epirubicin; Female; Fluorouracil; Humans; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Receptor, ErbB-2; Taxoids; Trastuzumab | 2018 |
Survival analysis of carboplatin added to an anthracycline/taxane-based neoadjuvant chemotherapy and HRD score as predictor of response-final results from GeparSixto.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Breast; Bridged-Ring Compounds; Carboplatin; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Mastectomy; Middle Aged; Mutation; Neoadjuvant Therapy; Paclitaxel; Polyethylene Glycols; Prognosis; Recombinational DNA Repair; Survival Analysis; Taxoids; Triple Negative Breast Neoplasms | 2018 |
Effect of Taxane Plus Platinum Regimens vs Doxorubicin Plus Cisplatin as Adjuvant Chemotherapy for Endometrial Cancer at a High Risk of Progression: A Randomized Clinical Trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Disease Progression; Doxorubicin; Endometrial Neoplasms; Female; Humans; Middle Aged; Paclitaxel; Risk; Taxoids; Treatment Outcome | 2019 |
Randomised phase II trial comparing four front-line doublets in Asian patients with metastatic gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asian People; Bridged-Ring Compounds; Cisplatin; Disease-Free Survival; Docetaxel; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Paclitaxel; Prospective Studies; Stomach Neoplasms; Taxoids | 2019 |
NSAS-BC02 substudy of chemotherapy-induced amenorrhea (CIA) in premenopausal patients who received either taxane alone or doxorubicin(A) cyclophosphamide(C) followed by taxane as postoperative chemotherapy.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Humans; Incidence; Lymphatic Metastasis; Mastectomy; Middle Aged; Paclitaxel; Premenopause; Prognosis; Prospective Studies; Receptors, Estrogen; Retrospective Studies; Taxoids; Young Adult | 2020 |
A prospective phase II clinical trial identifying the optimal regimen for carboplatin plus standard backbone of anthracycline and taxane-based chemotherapy in triple negative breast cancer.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Canada; Carboplatin; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Paclitaxel; Prospective Studies; Taxoids; Treatment Outcome; Triple Negative Breast Neoplasms | 2022 |
Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors.
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Glucocorticoids; Humans; Isoquinolines; Paclitaxel; Pancreatic Neoplasms; Pyrazoles; Pyridines; Receptors, Glucocorticoid; Taxoids | 2022 |
HALT-D: a randomized open-label phase II study of crofelemer for the prevention of chemotherapy-induced diarrhea in patients with HER2-positive breast cancer receiving trastuzumab, pertuzumab, and a taxane.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diarrhea; Docetaxel; Female; Humans; Paclitaxel; Quality of Life; Receptor, ErbB-2; Taxoids; Trastuzumab | 2022 |
Quality of life with docetaxel plus cisplatin versus paclitaxel plus carboplatin in patients with completely resected non-small cell lung cancer: quality of life analysis of TORG 0503.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; Humans; Lung Neoplasms; Paclitaxel; Quality of Life; Taxoids | 2023 |
A randomized controlled trial using surgical gloves to prevent chemotherapy-induced peripheral neuropathy by paclitaxel in breast cancer patients (AIUR trial).
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Gloves, Surgical; Humans; Paclitaxel; Peripheral Nervous System Diseases; Quality of Life; Taxoids | 2023 |
Other Studies
153 other study(ies) available for paclitaxel and taxane
| Article | Year |
|---|---|
A new large-scale process for taxol and related taxanes from Taxus brevifolia.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Paclitaxel; Pilot Projects; Plants, Medicinal; Taxoids | 1995 |
Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and "total taxanes" in Taxus brevifolia extracts by enzyme immunoassay.
Topics: Alkaloids; Animals; Antibodies, Monoclonal; Antibody Specificity; Bridged-Ring Compounds; Cross Reactions; Drugs, Chinese Herbal; Female; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Paclitaxel; Plant Extracts; Plant Leaves; Plants, Medicinal; Taxoids | 1995 |
Seasonal and tissue variation in taxane concentrations of Taxus brevifolia.
Topics: Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Paclitaxel; Seasons; Taxoids; Trees | 1994 |
[Taxanes--a new generation of cytostatic drugs].
Topics: Bridged Bicyclo Compounds; Bridged-Ring Compounds; Humans; Neoplasm Staging; Neoplasms; Paclitaxel; Survival Rate; Taxoids | 1993 |
Site-specific enzymatic hydrolysis of taxanes at C-10 and C-13.
Topics: Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Nocardiaceae; Paclitaxel; Substrate Specificity; Taxoids | 1994 |
Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew.
Topics: Antibodies, Monoclonal; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chromatography, Thin Layer; Culture Media; Humans; Immunoenzyme Techniques; KB Cells; Mitosporic Fungi; Paclitaxel; Spectrometry, Mass, Fast Atom Bombardment; Taxoids; Trees | 1993 |
Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Carcinoma; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Docetaxel; Drug Carriers; Female; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Paclitaxel; Taxoids | 1995 |
Molecular mobility of nitroxyl-labelled taxol during tubulin assembly.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Nitrogen Oxides; Paclitaxel; Spin Labels; Taxoids; Temperature; Tubulin | 1997 |
Determination of paclitaxel and related taxanes in bulk drug and injectable dosage forms by reversed phase liquid chromatography.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Dosage Forms; Fluorobenzenes; Paclitaxel; Phenols; Reference Standards; Reproducibility of Results; Taxoids; Thermodynamics | 1997 |
Miniaturized HPLC and ionspray mass spectrometry applied to the analysis of Paclitaxel and taxanes.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Mass Spectrometry; Paclitaxel; Taxoids | 1997 |
12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure.
Topics: Alkaloids; Animals; Antineoplastic Agents; Bridged-Ring Compounds; Crystallography, X-Ray; Female; Humans; Melanoma, Experimental; Mice; Mice, Inbred Strains; Molecular Conformation; Molecular Structure; Ovarian Neoplasms; Paclitaxel; Taxoids; Tumor Cells, Cultured | 1997 |
[New cytostatics in the therapy of non-small cell bronchial carcinoma].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Bronchial Neoplasms; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Paclitaxel; Taxoids; Vinblastine; Vinorelbine | 1998 |
Additive and supra-additive cytotoxicity of cisplatin-taxane combinations in ovarian carcinoma cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cell Division; Cisplatin; Drug Synergism; Female; Humans; Ovarian Neoplasms; Paclitaxel; Taxoids; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biopolymers; Bleomycin; Bridged-Ring Compounds; Cytarabine; DNA Damage; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Mice; Microtubule-Associated Proteins; Microtubules; Neoplasm Proteins; Paclitaxel; Rats; Taxoids; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays; Vinblastine; Vinca Alkaloids | 1999 |
A differential scanning calorimetry study of phosphocholines mixed with paclitaxel and its bromoacylated taxanes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Acylation; Bridged-Ring Compounds; Calorimetry, Differential Scanning; Dimyristoylphosphatidylcholine; Lipid Bilayers; Paclitaxel; Phosphatidylcholines; Taxoids | 2000 |
Anti-tumour activity of a panel of taxanes toward a cellular model of human cervical cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Bridged-Ring Compounds; Cell Cycle; DNA, Neoplasm; Docetaxel; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Paclitaxel; Taxoids; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2000 |
A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells.
Topics: Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Diterpenes; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Mutation; Paclitaxel; Protein Conformation; Structure-Activity Relationship; Taxoids; Thiazoles; Tubulin; Tumor Cells, Cultured | 2000 |
Preclinical evaluation of the cardiotoxicity of taxane-anthracycline combinations using the model of isolated perfused rat heart.
Topics: Animals; Anthracyclines; Bridged-Ring Compounds; Chemotherapy, Cancer, Regional Perfusion; Docetaxel; Doxorubicin; Drug Administration Schedule; Drug Combinations; Drug Synergism; Epirubicin; Heart; Liver; Male; Paclitaxel; Rats; Rats, Sprague-Dawley; Taxoids | 2000 |
A common pharmacophore for Taxol and the epothilones based on the biological activity of a taxane molecule lacking a C-13 side chain.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Humans; Models, Molecular; Paclitaxel; Protein Conformation; Structure-Activity Relationship; Taxoids | 2000 |
[Prognostic factors for survival of ovarian epithelial cancers: apropos of 287 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Paclitaxel; Prognosis; Risk Factors; Survival Rate; Taxoids | 2000 |
Oral efficacy and bioavailability of a novel taxane.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Paclitaxel; Taxoids; Transplantation, Heterologous; Treatment Outcome; Tumor Cells, Cultured | 2000 |
Management of patients with cancer of unknown primary site.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma; Etoposide; Evaluation Studies as Topic; Female; Humans; Male; Neoplasms, Unknown Primary; Paclitaxel; Prognosis; Survival Rate; Taxoids | 2000 |
Structural significance of the acyl group at the C-10 position and the A ring of the taxane core of paclitaxel for inducing nitric oxide and tumor necrosis factor production by murine macrophages.
Topics: Acylation; Animals; Bridged-Ring Compounds; Cell Division; Cells, Cultured; Enzyme Induction; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Paclitaxel; Taxoids; Tumor Necrosis Factor-alpha | 2000 |
Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Bridged-Ring Compounds; Cell Division; DNA Fragmentation; Dose-Response Relationship, Drug; G2 Phase; Humans; Mitosis; Paclitaxel; Taxoids; Tubulin; Tumor Cells, Cultured | 2000 |
Taxanes: the genetic toxicity of paclitaxel and docetaxel in somatic cells of Drosophila melanogaster.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Biotransformation; Bridged-Ring Compounds; Docetaxel; Drosophila melanogaster; Female; Genetic Markers; Larva; Male; Mutagenicity Tests; Paclitaxel; Radiation-Sensitizing Agents; Taxoids | 2001 |
Derivation and initial characterization of a mouse mammary tumor cell line carrying the polyomavirus middle T antigen: utility in the development of novel cancer therapeutics.
Topics: Adenoviridae; Alkyl and Aryl Transferases; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Bridged-Ring Compounds; Cell Division; Cisplatin; Deoxycytidine; Dose-Response Relationship, Drug; Farnesyltranstransferase; Female; Gemcitabine; Gene Transfer Techniques; Genes, p53; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Sequence Analysis, DNA; Taxoids; Time Factors; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2000 |
Hydrolyzable hydrophobic taxanes: synthesis and anti-cancer activities.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bridged-Ring Compounds; Cell Cycle; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms; Paclitaxel; Taxoids; Tubulin; Tumor Cells, Cultured | 2001 |
Biotransformation of a 4(20),11(12)-taxadiene derivative.
Topics: Alkenes; Antineoplastic Agents; Biotransformation; Bridged-Ring Compounds; Cunninghamella; Diterpenes; Fungi; Hydroxylation; Magnetic Resonance Spectroscopy; Paclitaxel; Stereoisomerism; Substrate Specificity; Taxoids | 2001 |
Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Heart; Humans; Myocardium; Paclitaxel; Taxoids; Tubulin; Vinblastine; Vinorelbine | 2001 |
Commercial taxane formulations induce stomatocytosis and increase blood viscosity.
Topics: Aged; Antineoplastic Agents, Phytogenic; Blood Viscosity; Bridged-Ring Compounds; Cardiovascular System; Docetaxel; Dose-Response Relationship, Drug; Erythrocytes; Female; Humans; Male; Middle Aged; Paclitaxel; Rheology; Surface-Active Agents; Taxoids; Time Factors | 2001 |
Targeted taxane therapy for cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Docosahexaenoic Acids; Humans; Neoplasms; Paclitaxel; Polyglutamic Acid; Prodrugs; Taxoids | 2002 |
Cyclooxygenase-2 induction by paclitaxel, docetaxel, and taxane analogues in human monocytes and murine macrophages: structure-activity relationships and their implications.
Topics: Animals; Antineoplastic Agents, Phytogenic; Binding, Competitive; Bridged-Ring Compounds; Cells, Cultured; Cyclooxygenase 2; Docetaxel; Enzyme Induction; Humans; Immunoenzyme Techniques; Isoenzymes; Macrophages; Membrane Proteins; Mice; Microtubules; Molecular Structure; Monocytes; Paclitaxel; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Structure-Activity Relationship; Taxoids; Tubulin | 2002 |
Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bridged-Ring Compounds; Cell Division; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neovascularization, Physiologic; Ovarian Neoplasms; Paclitaxel; Taxoids; Time Factors; Tubulin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
Regio- and stereoselective hydroxylation of taxoids by filamentous fungi.
Topics: Absidia; Biotransformation; Bridged-Ring Compounds; Fungi; Hydroxylation; Magnetic Resonance Spectroscopy; Molecular Structure; Paclitaxel; Stereoisomerism; Taxoids | 2002 |
Variation in content of taxol and related taxanes in Eastern Himalayan populations of Taxus wallichiana.
Topics: Asia, Western; Bridged-Ring Compounds; Paclitaxel; Plant Structures; Plants, Medicinal; Seasons; Taxoids; Taxus | 2002 |
New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 2.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Indicators and Reagents; Magnetic Resonance Spectroscopy; Paclitaxel; Solubility; Stereoisomerism; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2002 |
Three new C-14 oxygenated taxanes from the wood of Taxus yunnanensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Survival; Colonic Neoplasms; Diterpenes; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Fibrosarcoma; Humans; Hydrolysis; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Plants, Medicinal; Stereoisomerism; Taxoids; Taxus; Trees; Tumor Cells, Cultured | 2002 |
New minor taxanes analogues from the needles of Taxus canadenis.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Plant Leaves; Spectrometry, Mass, Fast Atom Bombardment; Taxoids; Taxus | 2003 |
Evaluation of a silica-based monolithic column in the HPLC analysis of taxanes.
Topics: Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drug Contamination; Molecular Conformation; Paclitaxel; Silicon Dioxide; Spectrophotometry, Ultraviolet; Taxoids | 2003 |
A delicate balance of energetics. Subtleties associated with alpha-ketol-based bridge migration to afford 9-keto-10beta-p-methoxybenzyloxytaxanes.
Topics: Bridged-Ring Compounds; Catalysis; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Cyclization; Hydroxylation; Indicators and Reagents; Molecular Structure; Oxidation-Reduction; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Taxoids; Thermodynamics | 2003 |
Chemical modification of a highly functionalized taxane. The consequences of an absent bridgehead double bond on oxetane D-ring construction.
Topics: Bridged-Ring Compounds; Catalysis; Combinatorial Chemistry Techniques; Cyclization; Indicators and Reagents; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Paclitaxel; Structure-Activity Relationship; Taxoids; Thermodynamics | 2003 |
Dependence of selectivity on eluent composition and temperature in the HPLC separation of taxanes using fluorinated and hydrocarbon phases.
Topics: Acetonitriles; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fluorocarbon Polymers; Paclitaxel; Solvents; Taxoids; Temperature | 2003 |
Immunoaffinity chromatography for the sample pretreatment of Taxus plant and cell extracts prior to analysis of taxanes by high-performance liquid chromatography.
Topics: Antibodies; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Immunochemistry; Immunoconjugates; Immunoglobulin G; Ovalbumin; Paclitaxel; Plant Extracts; Sepharose; Serum Albumin, Bovine; Solvents; Spectrophotometry, Ultraviolet; Taxoids; Taxus; Triterpenes | 2002 |
The design and synthesis of guanosine compounds with in vitro activity against the colon cancer cell line SW480: non-taxane derived mimics of taxol?
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Line, Tumor; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Guanosine; Humans; Microtubules; Paclitaxel; Structure-Activity Relationship; Taxoids | 2003 |
Substrate specificity for the hydroxylation of polyoxygenated 4(20),11-taxadienes by Ginkgo cell suspension cultures.
Topics: Alkenes; Biotransformation; Bridged-Ring Compounds; Cells, Cultured; Diterpenes; Ginkgo biloba; Hydroxylation; Molecular Structure; Paclitaxel; Plants, Medicinal; Substrate Specificity; Taxoids | 2003 |
Measuring the side effects of taxane therapy in oncology: the functional assesment of cancer therapy-taxane (FACT-taxane).
Topics: Antineoplastic Agents, Phytogenic; Attitude to Health; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Quality of Life; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Taxoids | 2003 |
Taxane production in suspension culture of Taxus x media var. Hicksii carried out in flasks and bioreactor.
Topics: Bioreactors; Bridged-Ring Compounds; Paclitaxel; Taxoids; Taxus | 2005 |
[LC-ESI-MS metabolic profiling analysis of taxanes from the extracts of Taxus chinensis cell cultures].
Topics: Alkaloids; Bridged-Ring Compounds; Cells, Cultured; Chromatography, Liquid; Molecular Structure; Molecular Weight; Paclitaxel; Plant Extracts; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Taxoids; Taxus | 2005 |
Predictive value of D-dimer plasma levels in response and progressive disease in patients with lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bridged-Ring Compounds; Camptothecin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Deoxycytidine; Disease Progression; Docetaxel; Female; Fibrin Fibrinogen Degradation Products; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Patient Compliance; Predictive Value of Tests; Prospective Studies; Survival Analysis; Taxoids; Treatment Outcome; Vinblastine | 2006 |
Influence of formulation vehicle on metronomic taxane chemotherapy: albumin-bound versus cremophor EL-based paclitaxel.
Topics: Albumins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aorta; Bridged-Ring Compounds; Cell Proliferation; Endothelium, Vascular; Female; Humans; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Paclitaxel; Polyethylene Glycols; Rats; Surface-Active Agents; Taxoids | 2006 |
[A recurrent ovarian cancer patient who achieved a complete response following irinotecan plus CDDP therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bridged-Ring Compounds; CA-125 Antigen; Camptothecin; Carcinoma, Endometrioid; Cisplatin; Drug Administration Routes; Drug Resistance, Neoplasm; Female; Humans; Irinotecan; Laparotomy; Ovarian Neoplasms; Paclitaxel; Remission Induction; Taxoids | 2007 |
A CERTain role for ceramide in taxane-induced cell death.
Topics: Bridged-Ring Compounds; Cell Death; Ceramides; Chromosomal Instability; Drug Resistance, Neoplasm; Humans; Mitosis; Paclitaxel; Polyploidy; Protein Folding; Protein Serine-Threonine Kinases; RNA, Small Interfering; Spindle Apparatus; Taxoids; Tumor Cells, Cultured | 2007 |
Taxane's substituents at C3' affect its regioselective metabolism: different in vitro metabolism of cephalomannine and paclitaxel.
Topics: Adult; Animals; Antineoplastic Agents; Biotransformation; Bridged-Ring Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Male; Microsomes, Liver; Middle Aged; Paclitaxel; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Swine; Swine, Miniature; Taxoids | 2008 |
Lx2-32c, a novel taxane and its antitumor activities in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Mice; Mice, Nude; Microtubules; Paclitaxel; Stomach Neoplasms; Taxoids; Tubulin; Xenograft Model Antitumor Assays | 2008 |
The taxol pathway 10-O-acetyltransferase shows regioselective promiscuity with the oxetane hydroxyl of 4-deacetyltaxanes.
Topics: Acetylation; Acetyltransferases; Antineoplastic Agents; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Heterocyclic Compounds; Hydroxylation; Magnetic Resonance Spectroscopy; Molecular Structure; Paclitaxel; Stereoisomerism; Substrate Specificity; Taxoids; Taxus | 2008 |
Effect of taxol feeding on taxol and related taxane production in Taxus baccata suspension cultures.
Topics: Bridged-Ring Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Paclitaxel; Taxoids; Taxus | 2009 |
Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate.
Topics: Acrylamides; Alendronate; Angiogenesis Inhibitors; Antineoplastic Agents; Bone Neoplasms; Bridged-Ring Compounds; Cathepsin B; Cells, Cultured; Humans; Paclitaxel; Polymers; Taxoids; Vascular Endothelial Growth Factor A | 2009 |
An N-aroyltransferase of the BAHD superfamily has broad aroyl CoA specificity in vitro with analogues of N-dearoylpaclitaxel.
Topics: Acyl Coenzyme A; Acyltransferases; Biocatalysis; Bridged-Ring Compounds; Escherichia coli; Kinetics; Paclitaxel; Plant Proteins; Substrate Specificity; Taxoids; Taxus | 2009 |
Chromosomal instability determines taxane response.
Topics: Bridged-Ring Compounds; Cell Survival; Chromosomal Instability; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Microtubules; Neoplasms; Paclitaxel; Polymerase Chain Reaction; Prognosis; Taxoids | 2009 |
Hypothyroidism as a consequence of intensity-modulated radiotherapy with concurrent taxane-based chemotherapy for locally advanced head-and-neck cancer.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Combined Modality Therapy; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Hypothyroidism; Male; Middle Aged; Paclitaxel; Radiation Injuries; Radiography; Radiotherapy, Intensity-Modulated; Retrospective Studies; Risk Factors; Taxoids; Thyroid Gland | 2010 |
C-7 configuration as one of determinants in taxanes metabolism by human cytochrome P450 enzymes.
Topics: Bridged-Ring Compounds; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Docetaxel; Enzyme Inhibitors; Female; Humans; Hydroxylation; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Conformation; Paclitaxel; Recombinant Proteins; Taxoids | 2009 |
Cyclostreptin and microtubules: is a low-affinity binding site required?
Topics: Binding Sites; Bridged-Ring Compounds; Epothilones; Excipients; Microtubules; Molecular Dynamics Simulation; Paclitaxel; Polycyclic Compounds; Taxoids; Tubulin | 2010 |
Outcomes after multiple lines of chemotherapy for platinum-resistant epithelial cancers of the ovary, peritoneum, and fallopian tube.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; CA-125 Antigen; Carcinoma; Carcinoma, Ovarian Epithelial; Cisplatin; Cytotoxins; Deoxycytidine; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fallopian Tube Neoplasms; Female; Gemcitabine; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Platinum; Polyethylene Glycols; Prognosis; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Taxoids; Treatment Outcome | 2011 |
[Retrospective analysis of trastuzumab treatment in 141 patients with Her-2 positive breast cancer].
Topics: Adult; Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Carboplatin; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paclitaxel; Receptor, ErbB-2; Retrospective Studies; Survival Rate; Taxoids; Trastuzumab; Treatment Failure | 2010 |
Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer.
Topics: Adenosine Triphosphate; Adult; Aged; Anthracyclines; Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Cell Line, Tumor; Cluster Analysis; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Profiling; HEK293 Cells; Humans; Kinesins; Middle Aged; Neoplasm Staging; Paclitaxel; Protein Binding; Taxoids; Vincristine | 2012 |
Dermatopathologic effects of taxane therapy.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Biopsy; Breast Neoplasms; Bridged-Ring Compounds; Cell Cycle; Docetaxel; Female; Humans; Leiomyosarcoma; Male; Mitosis; Paclitaxel; Skin; Skin Diseases; Taxoids | 2011 |
The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets.
Topics: Acetyltransferases; Acyltransferases; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Isomerases; Paclitaxel; Plant Components, Aerial; Plant Roots; Taxoids; Taxus | 2011 |
The determination of changes in the expression of genes for selected specific transcriptional factors in in vitro ductal breast cancer cells under the influence of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Pharmacological; Breast Neoplasms; Bridged-Ring Compounds; Carcinoma, Ductal, Breast; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotide Array Sequence Analysis; Paclitaxel; Primary Cell Culture; Prognosis; Taxoids; Transcription Factors; Tumor Cells, Cultured | 2011 |
Clusterin is a critical downstream mediator of stress-induced YB-1 transactivation in prostate cancer.
Topics: Apoptosis; Benzoquinones; Bridged-Ring Compounds; Cell Line, Tumor; Cell Proliferation; Clusterin; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leupeptins; Male; Paclitaxel; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; RNA, Small Interfering; Taxoids; Transcriptional Activation; Y-Box-Binding Protein 1 | 2011 |
Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in Taxus suspension cultures.
Topics: Acetates; Bridged-Ring Compounds; Cell Culture Techniques; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Paclitaxel; Plant Cells; Plant Proteins; Taxoids; Taxus | 2012 |
Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
Topics: Animals; Antineoplastic Agents; Bridged-Ring Compounds; Humans; Microtubules; Molecular Structure; Nocodazole; Paclitaxel; Polymerization; Structure-Activity Relationship; Taxoids; Tubulin | 2012 |
Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Carboplatin; Chemotherapy, Adjuvant; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Paclitaxel; Platinum Compounds; Predictive Value of Tests; Taxoids | 2012 |
A population-based study on the patterns of use of different chemotherapy regimens in Swiss patients with early breast cancer.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Capecitabine; Carboplatin; Confidence Intervals; Cyclophosphamide; Deoxycytidine; Doxorubicin; Epirubicin; Female; Fluorouracil; Gemcitabine; Health Services Accessibility; Humans; Logistic Models; Lymphatic Metastasis; Medication Adherence; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Paclitaxel; Receptors, Estrogen; Switzerland; Taxoids; Vinblastine; Vinorelbine | 2012 |
Association of HER-2 copy number and HER-2/CEP-17 ratio with neoadjuvant taxane-containing chemotherapy sensitivity in locally advanced breast cancer.
Topics: Adolescent; Adult; Aged; Algorithms; Antineoplastic Agents; Axilla; Breast Neoplasms; Bridged-Ring Compounds; Carboplatin; Chromosomes, Human, Pair 17; Female; Gene Dosage; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Logistic Models; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Prospective Studies; Receptor, ErbB-2; Taxoids; Young Adult | 2012 |
miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers.
Topics: Antineoplastic Agents; Base Sequence; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Paclitaxel; rap1 GTP-Binding Proteins; RNA Interference; RNA, Messenger; STAT3 Transcription Factor; Taxoids | 2012 |
Risk of treatment related death and febrile neutropaenia with taxane-based adjuvant chemotherapy for breast cancer in a middle income country outside a clinical trial setting.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Carboplatin; Cause of Death; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Doxorubicin; Epirubicin; Female; Fever; Fluorouracil; Humans; Malaysia; Middle Aged; Neutropenia; Paclitaxel; Retrospective Studies; Risk Factors; Taxoids | 2012 |
Lx2-32c, a novel taxane derivative, exerts anti-resistance activity by initiating intrinsic apoptosis pathway in vitro and inhibits the growth of resistant tumor in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Bridged-Ring Compounds; Caspase 3; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Female; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Microtubules; Mitochondria; Neoplasms; Paclitaxel; Poly(ADP-ribose) Polymerases; Polymerization; Proto-Oncogene Proteins c-bcl-2; Taxoids; Xenograft Model Antitumor Assays | 2012 |
Comparative effectiveness of platinum-based chemotherapy versus taxane and other regimens for ovarian cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cisplatin; Cohort Studies; Comparative Effectiveness Research; Female; Humans; Ovarian Neoplasms; Paclitaxel; Platinum Compounds; SEER Program; Taxoids | 2013 |
Pharmacogenetics, enzyme probes and therapeutic drug monitoring as potential tools for individualizing taxane therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Bridged-Ring Compounds; Docetaxel; Drug Monitoring; Female; Humans; Neoplasms; Paclitaxel; Pharmacogenetics; Precision Medicine; Taxoids | 2013 |
Clinical Significance of ABCG2 Haplotype-tagging Single Nucleotide Polymorphisms in Patients With Unresectable Non-Small Cell Lung Cancer Treated With First-line Platinum-based Chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Cisplatin; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; Haplotypes; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Paclitaxel; Polymorphism, Single Nucleotide; Predictive Value of Tests; Survival Rate; Taxoids; Treatment Outcome | 2015 |
Obesity, diabetes, and survival outcomes in a large cohort of early-stage breast cancer patients.
Topics: Anthracyclines; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Composition; Body Mass Index; Breast Neoplasms; Bridged-Ring Compounds; Cohort Studies; Diabetes Mellitus; Disease-Free Survival; Female; Humans; Middle Aged; Obesity; Paclitaxel; Receptor, ErbB-2; Receptors, Estrogen; Survival; Tamoxifen; Taxoids; Treatment Outcome | 2013 |
A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Bridged-Ring Compounds; Caspase 8; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; G2 Phase Cell Cycle Checkpoints; HeLa Cells; Humans; MCF-7 Cells; Microscopy, Fluorescence; Molecular Structure; Neoplasms; Paclitaxel; Polymerization; RNA Interference; Taxoids; Tubulin | 2013 |
Metabolic engineering of Nicotiana benthamiana for the increased production of taxadiene.
Topics: Acetates; Alkenes; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cyclopentanes; Diterpenes; Gene Silencing; Humans; Isomerases; Metabolic Engineering; Metabolic Networks and Pathways; Nicotiana; Oxylipins; Paclitaxel; Plant Growth Regulators; Polyisoprenyl Phosphates; Taxoids; Taxus | 2014 |
Stathmin protein level, a potential predictive marker for taxane treatment response in endometrial cancer.
Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Bridged-Ring Compounds; Cell Line, Tumor; Endometrial Neoplasms; Female; Gene Knockdown Techniques; Humans; Neoplasm Metastasis; Paclitaxel; Stathmin; Taxoids; Treatment Outcome | 2014 |
Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bridged-Ring Compounds; Female; Genome-Wide Association Study; Humans; Middle Aged; Neoplasm Staging; Odds Ratio; Paclitaxel; Peripheral Nervous System Diseases; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Taxoids | 2014 |
Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Humans; Male; Paclitaxel; Prostatic Neoplasms; Ribosomal Protein S6 Kinases; Signal Transduction; Taxoids; Y-Box-Binding Protein 1 | 2014 |
Influence of drug formulation on OATP1B-mediated transport of paclitaxel.
Topics: Animals; Antineoplastic Agents; Biological Transport; Bridged-Ring Compounds; Cell Line; Chemistry, Pharmaceutical; CHO Cells; Cricetulus; Docetaxel; Drug Interactions; HEK293 Cells; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Mice; Mice, Inbred DBA; Mice, Knockout; Oocytes; Organic Anion Transporters; Paclitaxel; Taxoids; Tissue Distribution; Xenopus laevis | 2014 |
Chemoradiotherapy with taxane is superior to conventional surgery and radiotherapy in the management of cutaneous angiosarcoma: a multicentre, retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Chemoradiotherapy; Combined Modality Therapy; Docetaxel; Drug Administration Schedule; Female; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Retrospective Studies; Scalp; Skin Neoplasms; Taxoids; Treatment Outcome | 2014 |
Analysis of pathological complete response rates with paclitaxel-based regimens in trimodality therapy for esophageal cancer.
Topics: Aged; Antineoplastic Agents; Antineoplastic Protocols; Bridged-Ring Compounds; Chemoradiotherapy; Combined Modality Therapy; Disease-Free Survival; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Paclitaxel; Remission Induction; Retrospective Studies; Taxoids | 2015 |
Mixed molecular weight copolymer nanoparticles for the treatment of drug-resistant tumors: formulation development and cytotoxicity.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Bridged-Ring Compounds; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Docetaxel; Drug Carriers; Drug Resistance, Neoplasm; Humans; Micelles; Molecular Weight; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Taxoids | 2014 |
Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer.
Topics: Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA-Binding Proteins; Female; Genetic Association Studies; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; NAD(P)H Dehydrogenase (Quinone); Nausea; Neoplasm Staging; Neutropenia; Paclitaxel; Polymorphism, Single Nucleotide; Taxoids; Thrombocytopenia | 2014 |
EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity.
Topics: Animals; Antineoplastic Agents; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Ephrin-B1; Head and Neck Neoplasms; HEK293 Cells; Human papillomavirus 6; Humans; Immunoblotting; MCF-7 Cells; Mice, Inbred C57BL; Microscopy, Confocal; Microtubule-Associated Proteins; Microtubules; Oncogene Proteins, Viral; Paclitaxel; Protein Binding; Repressor Proteins; RNA Interference; Taxoids | 2015 |
Protein kinase A type II-α regulatory subunit regulates the response of prostate cancer cells to taxane treatment.
Topics: Bridged-Ring Compounds; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Docetaxel; Humans; Male; Paclitaxel; Prostatic Neoplasms; Protein Kinase Inhibitors; Taxoids | 2014 |
SNPs and taxane toxicity in breast cancer patients.
Topics: Aged; Breast Neoplasms; Bridged-Ring Compounds; Cytochrome P-450 CYP3A; DNA-Binding Proteins; Docetaxel; Drug-Related Side Effects and Adverse Reactions; Endonucleases; Female; Genetic Association Studies; Humans; Middle Aged; Mucositis; Paclitaxel; Polymorphism, Single Nucleotide; Taxoids | 2014 |
Transcript profiling of jasmonate-elicited Taxus cells reveals a β-phenylalanine-CoA ligase.
Topics: Amino Acid Sequence; Amplified Fragment Length Polymorphism Analysis; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Computer Simulation; Cyclopentanes; Cytosol; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Genetic Association Studies; Ligases; Models, Molecular; Oxylipins; Paclitaxel; Phenylalanine; Plant Proteins; RNA, Messenger; Sequence Alignment; Tandem Mass Spectrometry; Taxoids; Taxus | 2016 |
ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bridged-Ring Compounds; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Paclitaxel; Taxoids | 2015 |
Pharmacokinetic synergy from the taxane extract of Taxus chinensis improves the bioavailability of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Bridged-Ring Compounds; Drug Synergism; Humans; Male; MCF-7 Cells; Mice, Inbred ICR; Molecular Structure; Paclitaxel; Plant Extracts; Rats, Sprague-Dawley; Taxoids; Taxus | 2015 |
Changes in gene transcription and taxane production in elicited cell cultures of Taxus × media and Taxus globosa.
Topics: Alkaloids; Amino Acids; Bridged-Ring Compounds; Cell Culture Techniques; Cyclodextrins; Indenes; Paclitaxel; Taxoids; Taxus; Transcription, Genetic | 2015 |
Innovative use of the taxol binding peptide overcomes key challenges of stable and high drug loading in polymeric nanomicelles.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Bridged-Ring Compounds; Cell Line, Tumor; Docetaxel; Drug Carriers; Drug Delivery Systems; Humans; Micelles; Molecular Sequence Data; Neoplasms; Paclitaxel; Peptides; Polyethylene Glycols; Taxoids | 2015 |
Estrogen receptor alpha (ESR1)-signaling regulates the expression of the taxane-response biomarker PRP4K.
Topics: Animals; Biomarkers, Tumor; Bridged-Ring Compounds; Cell Survival; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Humans; Mice; Paclitaxel; Protein Serine-Threonine Kinases; Ribonucleoprotein, U4-U6 Small Nuclear; Signal Transduction; Structure-Activity Relationship; Tamoxifen; Taxoids; Tumor Cells, Cultured | 2016 |
[A Case of Taxane-Pretreated Metastatic Gastric Cancer with Excellent Response to Nab-Paclitaxel].
Topics: Adenocarcinoma; Aged; Albumins; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Paclitaxel; Stomach Neoplasms; Taxoids | 2015 |
Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Bridged-Ring Compounds; Doxorubicin; Endothelium, Vascular; Female; Humans; MCF-7 Cells; Mice, Nude; Microvessels; Neoplasm Proteins; Neovascularization, Pathologic; Paclitaxel; Receptors, Notch; RNA Interference; Signal Transduction; Specific Pathogen-Free Organisms; Taxoids; Xenograft Model Antitumor Assays | 2016 |
A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level.
Topics: Antimitotic Agents; Automation; Biological Assay; Bridged-Ring Compounds; Cell Cycle; Cell Death; Cell Line, Tumor; DNA Replication; Fluorescence; Genes, Reporter; HEK293 Cells; Humans; Image Processing, Computer-Assisted; Mitosis; Paclitaxel; Single-Cell Analysis; Spatio-Temporal Analysis; Taxoids; Time-Lapse Imaging; Ubiquitination | 2017 |
Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
Topics: Antineoplastic Agents; Binding Sites; Bridged-Ring Compounds; Cryoelectron Microscopy; Image Processing, Computer-Assisted; Macrolides; Microtubules; Paclitaxel; Proteins; Taxoids; Tubulin | 2017 |
Comparative Effectiveness and Resource Usage in Patients Receiving First-line Taxane-based Chemotherapy for Stage IV Non-Small-cell Lung Cancer in a US Community Oncology Setting.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Community Networks; Female; Humans; Lung Neoplasms; Male; Nanoparticles; Neoplasm Staging; Paclitaxel; Retrospective Studies; Survival Analysis; Taxoids; United States; Withholding Treatment | 2017 |
Treatment Patterns and Overall Survival Associated with First-Line Systemic Therapy for Patients with Advanced Non-Small Cell Lung Cancer.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bridged-Ring Compounds; Carboplatin; Carcinoma, Non-Small-Cell Lung; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Pemetrexed; Proportional Hazards Models; Retrospective Studies; Taxoids | 2017 |
α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana.
Topics: alpha-Glucosidases; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Diterpenes; Glycoside Hydrolase Inhibitors; Humans; Molecular Structure; Paclitaxel; Plant Bark; Taxoids; Taxus | 2017 |
Cholic acid-based novel micellar nanoplatform for delivering FDA-approved taxanes.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Cell Line, Tumor; Cholic Acid; Docetaxel; Drug Carriers; Humans; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Taxoids | 2017 |
Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Hyperalgesia; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nicotine; Paclitaxel; Peripheral Nervous System Diseases; Receptors, Cholinergic; Taxoids | 2018 |
RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Topics: Animals; Bridged-Ring Compounds; Colorectal Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Proteins; Paclitaxel; Taxoids; Thrombospondins; Tumor Microenvironment; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2017 |
Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition.
Topics: Biomarkers, Tumor; Bridged-Ring Compounds; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Gefitinib; Gene Knockdown Techniques; Humans; Mutation; Neoplastic Stem Cells; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Taxoids | 2018 |
Incidence of infusion hypersensitivity reaction after withholding dexamethasone premedication in early breast cancer patients not experiencing two previous cycles of infusion hypersensitivity reaction for weekly paclitaxel chemotherapy.
Topics: Adult; Aged; Breast Neoplasms; Bridged-Ring Compounds; Cohort Studies; Dexamethasone; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Middle Aged; Paclitaxel; Premedication; Retrospective Studies; Taxoids | 2018 |
Advances in the Regulation of In Vitro Paclitaxel Production: Methylation of a Y-Patch Promoter Region Alters BAPT Gene Expression in Taxus Cell Cultures.
Topics: Bridged-Ring Compounds; Cells, Cultured; DNA Methylation; Gene Expression Regulation, Plant; Metabolic Networks and Pathways; Paclitaxel; Plant Proteins; Promoter Regions, Genetic; Taxoids; Taxus; Transcriptome | 2018 |
Taxane Induced Cystoid Macular Edema: Case Report and Integrated Pathogenic Theory.
Topics: Aged; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Humans; Macular Edema; Male; Paclitaxel; Taxoids | 2019 |
The Syk inhibitor R406 is a modulator of P-glycoprotein (ABCB1)-mediated multidrug resistance.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Bridged-Ring Compounds; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Neoplasm Recurrence, Local; Ovarian Neoplasms; Oxazines; Paclitaxel; Pyridines; RNA, Small Interfering; Syk Kinase; Taxoids | 2019 |
Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site.
Topics: Antineoplastic Agents; Binding Sites; Bridged-Ring Compounds; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Ligands; Microtubule Proteins; Models, Molecular; Paclitaxel; Selective Estrogen Receptor Modulators; Taxoids; Tubulin; Tubulin Modulators; Tumor Microenvironment | 2019 |
KRAS pathway expression changes in pancreatic cancer models by conventional and experimental taxanes.
Topics: Albumins; Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bridged-Ring Compounds; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Signal Transduction; Taxoids; Transcriptome | 2019 |
Importin-β/karyopherin-β1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region.
Topics: beta Karyopherins; Bridged-Ring Compounds; Drug Synergism; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Microtubules; Mitosis; Nuclear Pore Complex Proteins; Paclitaxel; Protein Binding; Taxoids | 2020 |
CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia.
Topics: Alopecia; Antineoplastic Agents; Bridged-Ring Compounds; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Docetaxel; Humans; Keratinocytes; Models, Theoretical; Organ Culture Techniques; Paclitaxel; Piperazines; Protein Kinase Inhibitors; Pyridines; Stem Cells; Taxoids | 2019 |
CoA recycling by a benzoate coenzyme A ligase in cascade reactions with aroyltransferases to biocatalyze paclitaxel analogs.
Topics: Alkaloids; Antineoplastic Agents; Benzoic Acid; Biocatalysis; Bridged-Ring Compounds; Carboxylic Acids; Catalysis; Coenzyme A Ligases; Escherichia coli; Kinetics; Paclitaxel; Rhodopseudomonas; Substrate Specificity; Taxoids | 2020 |
Downregulation of GPSM2 is associated with primary resistance to paclitaxel in breast cancer.
Topics: Aged; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mice; Middle Aged; Paclitaxel; RNA, Messenger; Taxoids; Xenograft Model Antitumor Assays | 2020 |
Rapid desensitization to antineoplastic drugs in an outpatient immunoallergology clinic: Outcomes and risk factors.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Bridged-Ring Compounds; Cetuximab; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Male; Middle Aged; Neoplasms; Outpatients; Paclitaxel; Portugal; Retrospective Studies; Risk Factors; Skin Tests; Taxoids; Trastuzumab; Young Adult | 2020 |
Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies.
Topics: Bridged-Ring Compounds; Metabolic Engineering; Paclitaxel; Saccharomyces cerevisiae; Taxoids | 2021 |
Hospital volume and beyond first-line palliative systemic treatment in metastatic oesophagogastric adenocarcinoma: A population-based study.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Esophageal Neoplasms; Esophagogastric Junction; Female; Hospitalization; Hospitals, High-Volume; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Netherlands; Paclitaxel; Palliative Care; Ramucirumab; Stomach Neoplasms; Taxoids | 2020 |
Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway.
Topics: Animals; Apoptosis; Breast Neoplasms; Bridged-Ring Compounds; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Mice, Inbred NOD; Mice, SCID; Microtubules; NF-kappa B; Paclitaxel; Prognosis; Protein Serine-Threonine Kinases; RNA, Small Interfering; Signal Transduction; Taxoids | 2020 |
Persistent taxane-induced neuropathy in elderly patients treated for localized breast cancer.
Topics: Aged; Breast Neoplasms; Bridged-Ring Compounds; Cohort Studies; Female; Humans; Paclitaxel; Peripheral Nervous System Diseases; Quality of Life; Taxoids | 2020 |
Self-assembled micelles of the (lipo) glycopeptides, teicoplanin, as taxane nanocarriers.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Cell Line, Tumor; Drug Carriers; Glycopeptides; Humans; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Solubility; Taxoids; Teicoplanin | 2021 |
Impact of previous nivolumab treatment on the response to taxanes in patients with recurrent/metastatic head and neck squamous cell carcinoma.
Topics: Aged; Bridged-Ring Compounds; Disease Progression; Docetaxel; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Retrospective Studies; Squamous Cell Carcinoma of Head and Neck; Taxoids; Treatment Outcome | 2021 |
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells.
Topics: Bridged-Ring Compounds; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Paclitaxel; Taxoids; Tumor Suppressor Protein p53 | 2022 |
Taxane-induced neuropathy: How serious is this problem for patients with early breast cancer?
Topics: Breast Neoplasms; Female; Humans; Paclitaxel; Peripheral Nervous System Diseases; Prospective Studies; Retrospective Studies; Taxoids | 2023 |
Gene expression pattern and taxane biosynthesis in a cell suspension culture of Taxus baccata L. subjected to light and a phenylalanine ammonia lyase (PAL) inhibitor.
Topics: Bridged-Ring Compounds; Cell Culture Techniques; Flavonoids; Gene Expression; Paclitaxel; Phenols; Phenylalanine Ammonia-Lyase; Taxoids; Taxus | 2022 |
Risk of Ocular Adverse Events With Taxane-Based Chemotherapy.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bridged-Ring Compounds; Child; Docetaxel; Female; Humans; Lacrimal Apparatus Diseases; Macular Edema; Middle Aged; Optic Nerve Diseases; Paclitaxel; Retrospective Studies; Tamoxifen; Taxoids | 2022 |
Cost-Effectiveness of Pharmacologic Treatment Options for Women With Endocrine-Refractory or Triple-Negative Metastatic Breast Cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carboplatin; Cost-Benefit Analysis; Doxorubicin; Female; Humans; Paclitaxel; Quality of Life; Taxoids | 2023 |
Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae.
Topics: Alkenes; Aminolevulinic Acid; Antioxidants; Bridged-Ring Compounds; Cytochrome P-450 Enzyme System; Diterpenes; Epoxy Compounds; Flavin-Adenine Dinucleotide; Hemin; Iron; Paclitaxel; Saccharomyces cerevisiae; Taxoids | 2022 |
Prospective Study Investigating the Efficacy and Safety of a Scalp Cooling Device for the Prevention of Alopecia in Women Undergoing (Neo)Adjuvant Chemotherapy for Breast Cancer.
Topics: Adult; Alopecia; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Cyclophosphamide; Docetaxel; Female; Humans; Paclitaxel; Prospective Studies; Scalp; Taxoids | 2022 |
Association of Taxane Type With Patient-Reported Chemotherapy-Induced Peripheral Neuropathy Among Patients With Breast Cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Docetaxel; Female; Humans; Middle Aged; Paclitaxel; Patient Reported Outcome Measures; Peripheral Nervous System Diseases; Prospective Studies; Quality of Life; Taxoids | 2022 |
Incorporating weekly carboplatin in anthracycline and paclitaxel-containing neoadjuvant chemotherapy for triple-negative breast cancer: propensity-score matching analysis and TIL evaluation.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Humans; Lymphocytes, Tumor-Infiltrating; Neoadjuvant Therapy; Paclitaxel; Triple Negative Breast Neoplasms | 2023 |
Serum sodium ions and chloride ions associated with taxane-induced peripheral neuropathy in Chinese patients with early-stage breast cancer: A nation-wide multicenter study.
Topics: Breast Neoplasms; Chlorides; East Asian People; Female; Humans; Paclitaxel; Peripheral Nervous System Diseases; Taxoids | 2023 |
Study on the thermal stability of nab-paclitaxel during hyperthermic intraperitoneal chemotherapy.
Topics: Albumin-Bound Paclitaxel; Humans; Hyperthermic Intraperitoneal Chemotherapy; Paclitaxel; Polymers; Serum Albumin, Human; Taxoids | 2023 |
Structural insight into the stabilization of microtubules by taxanes.
Topics: Microtubules; Paclitaxel; Taxoids; Tubulin | 2023 |
Treatment for taxane-resistant cutaneous angiosarcoma: A multicenter study of 50 Japanese cases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; East Asian People; Female; Hemangiosarcoma; Humans; Paclitaxel; Retrospective Studies; Skin Neoplasms; Taxoids | 2023 |
STEAP1 Knockdown Decreases the Sensitivity of Prostate Cancer Cells to Paclitaxel, Docetaxel and Cabazitaxel.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Humans; Male; Oxidoreductases; Paclitaxel; Prostate; Prostatic Neoplasms; Taxoids | 2023 |
A Three-Step Taxane Titration Protocol Decreases Hypersensitivity Reactions During First and Second Exposures.
Topics: Docetaxel; Drug Hypersensitivity; Epinephrine; Humans; Paclitaxel; Prospective Studies; Taxoids | 2023 |
An evaluation of the effect of lithium on taxane-induced neuropathy.
Topics: Antineoplastic Agents; Humans; Lithium; Paclitaxel; Peripheral Nervous System Diseases; Retrospective Studies; Taxoids | 2023 |
Cytochrome P450 Oxidoreductase (POR) Associated with Severe Paclitaxel-Induced Peripheral Neuropathy in Patients of European Ancestry from ECOG-ACRIN E5103.
Topics: Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Humans; Paclitaxel; Peripheral Nervous System Diseases; Quality of Life | 2023 |
Real-World First-Line Use of Pertuzumab With Different Taxanes for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: A Comparative Effectiveness Study Using US Electronic Health Records.
Topics: Breast Neoplasms; Docetaxel; Electronic Health Records; Female; Humans; Paclitaxel; Retrospective Studies; Taxoids; Trastuzumab | 2023 |
The Association Between Taxane Use and Lacrimal Disorders.
Topics: Docetaxel; Humans; Lacrimal Apparatus Diseases; Paclitaxel; Taxoids; United States | 2023 |
Novel α-Trifluoromethyl Chalcone Exerts Antitumor Effects Against Prostate Cancer Cells.
Topics: Androgen Antagonists; Androgens; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Humans; Male; Paclitaxel; Prostatic Neoplasms; Receptors, Androgen; Taxoids | 2023 |
Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Female; Humans; Lung Neoplasms; Paclitaxel; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Receptors, G-Protein-Coupled; Taxoids | 2023 |
Clinical benefit of switching from paclitaxel to docetaxel or vice versa in cutaneous angiosarcoma patients resistant to first taxane chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Hemangiosarcoma; Humans; Paclitaxel; Skin Neoplasms; Taxoids | 2023 |
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Topics: Microtubules; Paclitaxel; Taxoids; Tubulin | 2023 |
Computational redesign of taxane-10β-hydroxylase for de novo biosynthesis of a key paclitaxel intermediate.
Topics: Cytochrome P-450 Enzyme System; Escherichia coli; Paclitaxel; Taxoids; Taxus | 2023 |
Immunotherapy as a later-line option for
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Lung Neoplasms; Paclitaxel; Taxoids | 2023 |