Page last updated: 2024-08-25

oxazolidin-2-one and torcetrapib

oxazolidin-2-one has been researched along with torcetrapib in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (18.92)29.6817
2010's29 (78.38)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Duriez, P1
Hegele, RA; Joy, TR1
Bloomfield, D; Briscoe, RJ; Brown, PN; Cumiskey, AM; Ehrhart, J; Forrest, MJ; Hershey, JC; Keller, WJ; Ma, X; McPherson, HE; Messina, E; Peterson, LB; Sharif-Rodriguez, W; Siegl, PK; Sinclair, PJ; Sparrow, CP; Stevenson, AS; Sun, SY; Tsai, C; Vargas, H; Walker, M; West, SH; White, V; Woltmann, RF1
Hegele, RA; Joy, T1
Masterjohn, C1
Shinkai, H2
Stroes, ES; Vergeer, M1
Böhm, M; Laufs, U; Pöss, J1
Addona, G; Bierilo, KK; Chen, Q; Chen, Y; Elowe, NH; Eveland, S; Fisher, TS; Frantz-Wattley, B; Garcia-Calvo, M; Houde, C; Hubbard, B; Kavana, M; Koblan, KS; Milot, D; O'Neill, EA; Porter, G; Ranalletta, M; Sinclair, P; Sitlani, A; Sparrow, C; Tung, E1
Hausenloy, DJ; Opie, L; Yellon, DM1
Blum-Kaelin, D; Chaput, E; Clerc, RG; Dernick, G; Huber, W; Kakutani, M; Magg, C; Matile, H; Maugeais, C; Niesor, EJ; Ogawa, N; Okamoto, H; Pflieger, P; Schmid, G; Takahashi, D; Thoma, R; von der Mark, E1
Katsnelson, A1
Athyros, VG; Katsiki, N; Mikhailidis, DP1
Devaraj, S; Jialal, I1
Niesor, EJ1
Ghosh, RK; Ghosh, SM1
Fisher, EA; Hewing, B1
Deanfield, J; Kastelein, J; Landmesser, U; Lüscher, TF; von Eckardstein, A1
Duivenvoorden, R; Fayad, ZA1
Akhlaghi, F; Mohammadpour, AH1
Cai, J; Chen, C; Hu, Z; Li, C; Li, Y; Liu, L; Luo, H; Pei, F; Zeng, C; Zhang, W; Zhou, F; Zhou, L1
deGoma, EM; Rader, DJ1
Francis, DP; Keene, D; Price, C; Shun-Shin, MJ1
McCullough, PA; Shin, HJ1
Even, S; Montezano, AC; Neves, KB; Nguyen Dinh Cat, A; Palacios, R; Rios, FJ; Touyz, RM1
Barter, PJ; Kastelein, JJ; Nicholls, SJ; Rye, KA1
Boekholdt, SM; Hovingh, GK; Ray, KK1
Quintão, EC1
Barkas, F; Elisaf, M; Filippatos, TD; Klouras, E1
Avorn, J; Franklin, JM; Hey, SP; Kesselheim, AS1
Cao, Y; Hao, D; Yang, Z; Yuan, X; Zhang, L; Zhang, S1
Charles, MA; Johns, DG; Krauss, RM; Lei, D; Peng, B; Ren, G; Rye, KA; Yang, M; Zhang, L; Zhang, M1
Corsini, A; Macchi, C; Matsuzawa, Y; Ruscica, M; Sirtori, CR; Yamashita, S1
Ahsan, M; Dixit, SM; Senapati, S1
Bis, JC; Charoen, P; Chaturvedi, N; Drenos, F; Finan, C; Franceschini, N; Gaunt, TR; Giambartolomei, C; Gordillo-Marañón, M; Hingorani, AD; Hughes, AD; Hunt, NB; Kivimaki, M; Lawlor, DA; Mook-Kanamori, DO; O'Donnell, CJ; Papacosta, O; Price, JF; Schmidt, AF; Sofat, R; Wannamethee, G; Wong, A; Zwierzyna, M1

Reviews

18 review(s) available for oxazolidin-2-one and torcetrapib

ArticleYear
The end of the road for CETP inhibitors after torcetrapib?
    Current opinion in cardiology, 2009, Volume: 24, Issue:4

    Topics: Amides; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2009
Cholesteryl ester transfer protein inhibitors as high-density lipoprotein raising agents.
    Expert opinion on therapeutic patents, 2009, Volume: 19, Issue:9

    Topics: Amides; Animals; Anticholesteremic Agents; Atherosclerosis; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Clinical Trials, Phase III as Topic; Esters; Humans; Oxazolidinones; Patents as Topic; Quinolines; Sulfhydryl Compounds

2009
The pharmacology and off-target effects of some cholesterol ester transfer protein inhibitors.
    The American journal of cardiology, 2009, Nov-16, Volume: 104, Issue:10 Suppl

    Topics: Aldosterone; Amides; Animals; Anticholesteremic Agents; Atherosclerosis; Blood Pressure; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Corticosterone; Esters; Humans; Hydrocortisone; Hypercholesterolemia; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2009
[HDL and CETP in atherogenesis].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:5

    Topics: Amides; Anticholesteremic Agents; Atherosclerosis; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Coronary Artery Disease; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Style; Nicotinic Acids; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Sulfhydryl Compounds; Treatment Outcome

2010
Different effects of compounds decreasing cholesteryl ester transfer protein activity on lipoprotein metabolism.
    Current opinion in lipidology, 2011, Volume: 22, Issue:4

    Topics: Amides; Animals; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Clinical Trials as Topic; Esters; Humans; Lipoproteins, HDL; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2011
Current status of CETP inhibitors in the treatment of hyperlipidemia: an update.
    Current clinical pharmacology, 2012, Volume: 7, Issue:2

    Topics: Amides; Animals; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Esters; Humans; Hyperlipidemias; Oxazolidinones; Quinolines; Risk Factors; Sulfhydryl Compounds

2012
Rationale for cholesteryl ester transfer protein inhibition.
    Current opinion in lipidology, 2012, Volume: 23, Issue:4

    Topics: Amides; Animals; Benzodiazepines; Cholesterol Ester Transfer Proteins; Drug Discovery; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2012
Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases.
    Vascular health and risk management, 2012, Volume: 8

    Topics: Amides; Animals; Biomarkers; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Esters; Humans; Hypolipidemic Agents; Oxazolidinones; Quinolines; Sulfhydryl Compounds; Treatment Outcome

2012
Safety of CETP inhibition.
    Current opinion in lipidology, 2012, Volume: 23, Issue:6

    Topics: Amides; Animals; Benzodiazepines; Cholesterol Ester Transfer Proteins; Esters; Humans; Oxazolidinones; Quinolines; Safety; Sulfhydryl Compounds

2012
Cholesteryl ester transfer protein inhibitors in the treatment of dyslipidemia: a systematic review and meta-analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Amides; Anticholesteremic Agents; Benzodiazepines; Blood Pressure; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Dyslipidemias; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Sulfhydryl Compounds; Treatment Outcome; Triglycerides

2013
Future of cholesteryl ester transfer protein inhibitors.
    Annual review of medicine, 2014, Volume: 65

    Topics: Amides; Anticholesteremic Agents; Atherosclerosis; Benzodiazepines; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2014
Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients.
    BMJ (Clinical research ed.), 2014, Jul-18, Volume: 349

    Topics: Amides; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Coronary Disease; Esters; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, HDL; Myocardial Infarction; Niacin; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Stroke; Sulfhydryl Compounds

2014
Focus on lipids: high-density lipoprotein cholesterol and its associated lipoproteins in cardiac and renal disease.
    Nephron. Clinical practice, 2014, Volume: 127, Issue:1-4

    Topics: Amides; Apolipoprotein A-I; Benzodiazepines; Black or African American; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Esters; Heart Diseases; Humans; Hyperlipoproteinemias; Kidney Diseases; Liver; Niacin; Observational Studies as Topic; Oxazolidinones; Prospective Studies; Quinolines; Randomized Controlled Trials as Topic; Risk; Sulfhydryl Compounds; Triglycerides; White People

2014
The controversy over the use of cholesteryl ester transfer protein inhibitors: is there some light at the end of the tunnel?
    European journal of clinical investigation, 2016, Volume: 46, Issue:6

    Topics: Amides; Animals; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Benzodiazepines; Cholesterol Ester Transfer Proteins; Esters; Humans; Hypercholesterolemia; Mice; Oxazolidinones; Quinolines; Rabbits; Sulfhydryl Compounds

2016
Cholesteryl ester transfer protein inhibitors: challenges and perspectives.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:8

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Esters; Humans; Lipids; Lipoprotein(a); Lipoproteins, HDL; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2016
Success, Failure, and Transparency in Biomarker-Based Drug Development: A Case Study of Cholesteryl Ester Transfer Protein Inhibitors.
    Circulation. Cardiovascular quality and outcomes, 2017, Volume: 10, Issue:6

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Biomarkers, Pharmacological; Cholesterol Ester Transfer Proteins; Drug Approval; Drug Discovery; Dyslipidemias; Endpoint Determination; Esters; Humans; Lipids; Oxazolidinones; Predictive Value of Tests; Quinolines; Reproducibility of Results; Sulfhydryl Compounds; Time Factors; Treatment Outcome

2017
Cholesteryl ester transfer protein: An enigmatic pharmacology - Antagonists and agonists.
    Atherosclerosis, 2018, Volume: 278

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Esters; Humans; Lignans; Lipoproteins, HDL; Lipoproteins, VLDL; Oxazolidinones; Probucol; Quinolines; Sulfhydryl Compounds; Triglycerides

2018
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
    Nature communications, 2021, 09-24, Volume: 12, Issue:1

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Coronary Disease; Esters; Humans; Mendelian Randomization Analysis; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2021

Other Studies

19 other study(ies) available for oxazolidin-2-one and torcetrapib

ArticleYear
Treating high-density lipoprotein cholesterol: a return to inhibition of cholesteryl ester transfer protein?
    Current atherosclerosis reports, 2008, Volume: 10, Issue:3

    Topics: Anticholesteremic Agents; Atherosclerosis; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Heart Diseases; Humans; Oxazolidinones; Quinolines; Risk Factors

2008
The failure of torcetrapib: what have we learned?
    British journal of pharmacology, 2008, Volume: 154, Issue:7

    Topics: Aldosterone; Anticholesteremic Agents; Blood Pressure; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Humans; Hyperaldosteronism; Oxazolidinones; Quinolines

2008
Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone.
    British journal of pharmacology, 2008, Volume: 154, Issue:7

    Topics: Adrenal Cortex; Aldosterone; Animals; Anticholesteremic Agents; Blood Pressure; Cholesterol Ester Transfer Proteins; Corticosterone; Dogs; Drug Evaluation, Preclinical; Female; Macaca mulatta; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle, Smooth, Vascular; Oxazolidinones; Quinolines; Rats; Rats, Sprague-Dawley; Species Specificity

2008
Effect of cholesteryl ester transfer protein inhibitor on vitamin E transport should be studied.
    American heart journal, 2009, Volume: 158, Issue:1

    Topics: Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Humans; Hypercholesterolemia; Oxazolidinones; Quinolines; Treatment Outcome; Triglycerides; Vitamin E

2009
Biochemical characterization of cholesteryl ester transfer protein inhibitors.
    Journal of lipid research, 2010, Volume: 51, Issue:9

    Topics: Amides; Animals; Anticholesteremic Agents; Blood Proteins; Cholesterol Ester Transfer Proteins; Esters; Humans; Mice; Molecular Structure; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2010
Dissociating HDL cholesterol from cardiovascular risk.
    Lancet (London, England), 2010, Jul-31, Volume: 376, Issue:9738

    Topics: Amides; Anticholesteremic Agents; Biomarkers; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxazolidinones; Predictive Value of Tests; Primary Prevention; Quinolines; Risk Assessment; Risk Factors; Secondary Prevention; Sulfhydryl Compounds

2010
Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport.
    Journal of lipid research, 2010, Volume: 51, Issue:12

    Topics: Amides; Animals; Anticholesteremic Agents; Bile Acids and Salts; Binding Sites; Biological Transport; Cholesterol; Cholesterol Ester Transfer Proteins; Cricetinae; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Esters; High-Density Lipoproteins, Pre-beta; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2010
Good news for 'good' cholesterol.
    Nature, 2010, Nov-18, Volume: 468, Issue:7322

    Topics: Amides; C-Reactive Protein; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Esters; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2010
Trial watch: hope renewed for strategy to raise HDL cholesterol.
    Nature reviews. Drug discovery, 2011, Volume: 10, Issue:1

    Topics: Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Clinical Trials, Phase II as Topic; Dyslipidemias; Humans; Oxazolidinones; Quinolines; Risk Factors

2011
The DEFINE study: a bright future for CETP inhibitors?
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:3

    Topics: Animals; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Dyslipidemias; Humans; Oxazolidinones; Quinolines

2011
Novel cholesteryl ester transfer protein inhibitors: promising therapy for dyslipidemia?
    Metabolic syndrome and related disorders, 2011, Volume: 9, Issue:3

    Topics: Cholesterol Ester Transfer Proteins; Drugs, Investigational; Dyslipidemias; Humans; Hypolipidemic Agents; Molecular Targeted Therapy; Oxazolidinones; Quinolines

2011
Increasing high-density lipoprotein cholesterol by cholesteryl ester transfer protein-inhibition: a rocky road and lessons learned? The early demise of the dal-HEART programme.
    European heart journal, 2012, Volume: 33, Issue:14

    Topics: Acute Coronary Syndrome; Amides; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Early Termination of Clinical Trials; Esters; Humans; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Sulfhydryl Compounds

2012
Future of cholesteryl ester transfer protein (CETP) inhibitors: a pharmacological perspective.
    Clinical pharmacokinetics, 2013, Volume: 52, Issue:8

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Coronary Artery Disease; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2013
Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:1

    Topics: Adipocytes; Aldosterone; Amides; Animals; Cell Line; Cholesterol Ester Transfer Proteins; Esters; Humans; Mice; NADPH Oxidases; Oxazolidinones; Phosphorylation; Quinolines; Reactive Oxygen Species; STAT3 Transcription Factor; Sulfhydryl Compounds

2015
Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP Inhibition as a Strategy to Reduce Cardiovascular Risk: The Pro Case.
    Circulation, 2015, Aug-04, Volume: 132, Issue:5

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Esters; Humans; Lipid Metabolism, Inborn Errors; Mice; Oxazolidinones; Quinolines; Rabbits; Risk Factors; Sulfhydryl Compounds; Treatment Outcome

2015
Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP as a Target to Lower CVD Risk: Suspension of Disbelief?
    Circulation, 2015, Aug-04, Volume: 132, Issue:5

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Esters; Humans; Lipid Metabolism, Inborn Errors; Mice; Oxazolidinones; Quinolines; Rabbits; Risk Factors; Sulfhydryl Compounds; Treatment Outcome

2015
Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:10

    Topics: Anticholesteremic Agents; Benzodiazepines; Binding Sites; Cholesterol Ester Transfer Proteins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Oxazolidinones; Protein Binding; Protein Structure, Secondary; Quinolines; Solvents; Thermodynamics

2018
Assessing the mechanisms of cholesteryl ester transfer protein inhibitors.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017, Volume: 1862, Issue:12

    Topics: Amides; Cholesterol Ester Transfer Proteins; Esters; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Multiprotein Complexes; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2017
Steering the Lipid Transfer To Unravel the Mechanism of Cholesteryl Ester Transfer Protein Inhibition.
    Biochemistry, 2019, 09-10, Volume: 58, Issue:36

    Topics: Binding Sites; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Humans; Hydrophobic and Hydrophilic Interactions; Lipoproteins, HDL; Lipoproteins, LDL; Molecular Dynamics Simulation; Oxazolidinones; Protein Binding; Protein Conformation; Quinolines

2019
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